#=GF ID   K-cyclin_vir_C
#=GF AC   PF09080.5
#=GF DE   K cyclin, C terminal
#=GF AU   Sammut SJ
#=GF SE   pdb_1g3n
#=GF GA   25.30 25.30;
#=GF TC   25.70 134.40;
#=GF NC   24.10 25.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Cyclin
#=GF RN   [1]
#=GF RM   11124804
#=GF RT   Structural basis of inhibition of CDK-cyclin complexes by INK4
#=GF RT   inhibitors. 
#=GF RA   Jeffrey PD, Tong L, Pavletich NP; 
#=GF RL   Genes Dev. 2000;14:3115-3125.
#=GF DR   INTERPRO; IPR015164;
#=GF DR   SCOP; 1g3n; fa;
#=GF CC   Members of this family adopt a secondary structure consisting of
#=GF CC   a five alpha-helix cyclin fold. Interaction with cyclin
#=GF CC   dependent kinases (CDKs) at a PSTAIRE sequence motif within the
#=GF CC   catalytic cleft of CDK results in the regulation of CDK activity
#=GF CC   [1].
#=GF SQ   10
#=GS O40946_HHV8/148-253   AC O40946.1
#=GS O40946_HHV8/148-253   DR PDB; 1G3N C; 148-253;
#=GS O40946_HHV8/148-253   DR PDB; 1G3N G; 148-253;
#=GS O12682_HHV8/148-253   AC O12682.1
#=GS P88962_HHV8/148-253   AC P88962.1
#=GS Q98147_HHV8/148-253   AC Q98147.1
#=GS Q9WRM3_9GAMA/148-246  AC Q9WRM3.1
#=GS Q9J2H1_9GAMA/148-246  AC Q9J2H1.1
#=GS Q53CR8_9GAMA/148-246  AC Q53CR8.1
#=GS E5LC00_HHV8/148-253   AC E5LC00.1
#=GS F5HC81_HHV8/148-253   AC F5HC81.1
#=GS Q77Q36_HHV8P/148-253  AC Q77Q36.1
O40946_HHV8/148-253              AVLATDVTSFLLLKLLGGSQHLDFWHHEVNTLITKALVDPKTGSLPASIISAAGCALLVPANVIPQDTHSGGVVPQLASILGCDVSVLQAAVEQILTSVSDFDL.RI...
#=GR O40946_HHV8/148-253   SS    ---CHHHHHHHHHHHS-SSTTHHHHHHHHHHHHHHHHCSTTGGGS-HHHHHHHHHHHHS-GGGS--XXXXX-HHHHHHHHHT--HHHHHHHHHHHHHHHHH---.--...
O12682_HHV8/148-253              AVLATDVTSFLLLKLLGGSQHLDFWHHEVDTLITKALVDPKTGSLPASIISAAGCALLVPANVIPQDTHSGGVVPQLASILGCDVSVLQAAVEQILTSVSDFDL.RI...
P88962_HHV8/148-253              AVLATDVTSFLLLKLLGGSQHLDFWHHEVNTLITKALVDPKTGSLPASIISAAGCALLVPANVIPQDTHSGGVVPQLASILGCDVSVLQAAVEQILTSVSDFDL.RI...
Q98147_HHV8/148-253              AVLATDVTSFLLLKLVGGSQHLDFWHHEVNTLITKALVDPKTGSLPASIISAAGCALLVPANVIPQDTHSGGVVPQLASILGCDVSVLQAAVEQILTSVSDFDL.RI...
Q9WRM3_9GAMA/148-246             AVLPTDAIGPTLFKSGFTKEQLFALHSQVVESVHKAIVNPATGGLPPSLVAAA-CALFSLGAAAPPPA-------RLAEAVGVSAATLAAAAESVATTLREFDE.--dhi
Q9J2H1_9GAMA/148-246             AVLPTDAIGPTLFKSGFTKEQLFALHSQVVESVHKAIVNPATGGLPPSLVAAA-CALFSLGAAAPPPA-------RLAEAVGVSAATLAAAAESVATTLREFDEdRI...
Q53CR8_9GAMA/148-246             AVLPTDAIGPALFKSGFTKEQLFALHSRVVESVHKAIVNPVTGGLSPSLVAAA-CALFSLGAAAPPLD-------KLAEAIGVSAATLTAAAESVATTLRELDEdRI...
E5LC00_HHV8/148-253              AVLATDVTSFLLLKLLGGSQHLDFWHHEVNTLITKALVDPKTGSLPASIISAAGCALLVPANVIPQDTHSGGVVPQLASILGCDVSVLQAAVEQILTSVSDFDL.RI...
F5HC81_HHV8/148-253              AVLATDVTSFLLLKLLGGSQHLDFWHHEVNTLITKALVDPKTGSLPASIISAAGCALLVPANVIPQDTHSGGVVPQLASILGCDVSVLQAAVEQILTSVSDFDL.RI...
Q77Q36_HHV8P/148-253             AVLATDVTSFLLLKLLGGSQHLDFWHHEVNTLITKALVDPKTGSLPASIISAAGCALLVPANVIPQDTHSGGVVPQLASILGCDVSVLQAAVEQILTSVSDFDL.RI...
#=GC SS_cons                     ---CHHHHHHHHHHHS-SSTTHHHHHHHHHHHHHHHHCSTTGGGS-HHHHHHHHHHHHS-GGGS--XXXXX-HHHHHHHHHT--HHHHHHHHHHHHHHHHH---.--...
#=GC seq_cons                    AVLATDVTSFLLLKLLGGSQHLDFWHHEVNTLITKALVDPKTGSLPASIISAAGCALLVPANVIPQDTHSGGVVPQLASILGCDVSVLQAAVEQILTSVSDFDL.RI...
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