GenomeNet

Database: Pfam
Entry: Kelch_2
LinkDB: Kelch_2
Original site: Kelch_2 
#=GF ID   Kelch_2
#=GF AC   PF07646.10
#=GF DE   Kelch motif
#=GF AU   Finn RD
#=GF SE   Context Domains
#=GF GA   21.30 21.30;
#=GF TC   21.30 21.30;
#=GF NC   21.20 21.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Repeat
#=GF WK   Kelch_motif
#=GF RN   [1]
#=GF RM   8126718
#=GF RT   Drosophila kelch motif is derived from a common enzyme fold. 
#=GF RA   Bork P, Doolittle RF; 
#=GF RL   J Mol Biol 1994;236:1277-1282.
#=GF RN   [2]
#=GF RM   2002850
#=GF RT   Novel thioether bond revealed by a 1.7 A crystal structure of
#=GF RT   galactose oxidase. 
#=GF RA   Ito N, Phillips SE, Stevens C, Ogel ZB, McPherson MJ, Keen JN,
#=GF RA   Yadav KD, Knowles PF; 
#=GF RL   Nature 1991;350:87-90.
#=GF RN   [3]
#=GF RM   15475350
#=GF RT   Crystal structure of the Kelch domain of human Keap1. 
#=GF RA   Li X, Zhang D, Hannink M, Beamer LJ; 
#=GF RL   J Biol Chem 2004;279:54750-54758.
#=GF DR   INTERPRO; IPR011498;
#=GF DR   SCOP; 1gof; fa;
#=GF CC   The kelch motif was initially discovered in Kelch
#=GF CC   (Swiss:Q04652). In this protein there are six copies of the
#=GF CC   motif.  It has been shown that Swiss:Q04652 is related to
#=GF CC   Galactose Oxidase [1] for which a structure has been solved [2].
#=GF CC   The kelch motif forms a beta sheet.  Several of these sheets
#=GF CC   associate to form a beta propeller structure as found in
#=GF CC   Pfam:PF00064, Pfam:PF00400 and Pfam:PF00415.
#=GF SQ   698
#=GS F6HAE8_VITVI/332-380    AC F6HAE8.1
#=GS F7DPY2_ORNAN/67-113     AC F7DPY2.1
#=GS F1A0D1_DICPU/235-278    AC F1A0D1.1
#=GS G6Z7A6_VIBCL/256-318    AC G6Z7A6.1
#=GS RABEK_HUMAN/30-82       AC Q7Z6M1.1
#=GS H2N8X3_PONAB/231-277    AC H2N8X3.1
#=GS G7AE79_VIBCL/256-318    AC G7AE79.1
#=GS B9FFS6_ORYSJ/235-292    AC B9FFS6.1
#=GS G7G667_9GAMM/241-299    AC G7G667.1
#=GS G1SFN8_RABIT/179-233    AC G1SFN8.1
#=GS D2A260_TRICA/12-62      AC D2A260.1
#=GS FBX42_HUMAN/231-277     AC Q6P3S6.1
#=GS D8TFE7_SELML/114-160    AC D8TFE7.1
#=GS Q10AZ7_ORYSJ/137-180    AC Q10AZ7.1
#=GS E0W0R9_PEDHC/299-354    AC E0W0R9.1
#=GS G1N686_MELGA/199-260    AC G1N686.2
#=GS F4QE47_DICFS/309-356    AC F4QE47.1
#=GS F8YZM5_VIBCL/256-318    AC F8YZM5.1
#=GS H3B3K4_LATCH/230-276    AC H3B3K4.1
#=GS G7AQ17_VIBCL/256-318    AC G7AQ17.1
#=GS H2MBZ4_ORYLA/13-63      AC H2MBZ4.1
#=GS H0V387_CAVPO/231-277    AC H0V387.1
#=GS G3X961_MOUSE/295-349    AC G3X961.1
#=GS A3F4K1_BRAJU/70-117     AC A3F4K1.1
#=GS A2P7A7_VIBCL/60-110     AC A2P7A7.1
#=GS I1JR48_SOYBN/27-72      AC I1JR48.1
#=GS F1N1V7_BOVIN/533-580    AC F1N1V7.1
#=GS G7AYJ7_VIBCL/60-110     AC G7AYJ7.1
#=GS F1L6W8_ASCSU/198-237    AC F1L6W8.1
#=GS G3NH48_GASAC/202-240    AC G3NH48.1
#=GS F0ZFQ5_DICPU/218-263    AC F0ZFQ5.1
#=GS C6RWJ2_VIBCL/60-110     AC C6RWJ2.1
#=GS E3WSG5_ANODA/77-122     AC E3WSG5.1
#=GS F8ZAA1_VIBCL/256-318    AC F8ZAA1.1
#=GS G2HEE4_PANTR/127-174    AC G2HEE4.1
#=GS B0R0N5_DANRE/297-351    AC B0R0N5.1
#=GS G2WNS3_YEASK/453-507    AC G2WNS3.1
#=GS A3CC67_ORYSJ/548-597    AC A3CC67.1
#=GS D3PFJ0_9MAXI/124-165    AC D3PFJ0.1
#=GS F1PIC6_CANFA/40-92      AC F1PIC6.1
#=GS G1PDW7_MYOLU/33-85      AC G1PDW7.1
#=GS G1TSS6_RABIT/179-233    AC G1TSS6.1
#=GS D8SF38_SELML/51-139     AC D8SF38.1
#=GS B3L5C2_PLAKH/1535-1580  AC B3L5C2.1
#=GS G3NJD1_GASAC/180-229    AC G3NJD1.1
#=GS G3PWG8_GASAC/38-85      AC G3PWG8.1
#=GS G1MDT2_AILME/33-85      AC G1MDT2.1
#=GS D7MSB0_ARALL/226-275    AC D7MSB0.1
#=GS H9GFN8_ANOCA/32-90      AC H9GFN8.1
#=GS G3UYQ6_MOUSE/196-235    AC G3UYQ6.1
#=GS H3DA96_TETNG/202-244    AC H3DA96.1
#=GS D7LGU6_ARALL/331-379    AC D7LGU6.1
#=GS C3ZRY1_BRAFL/4-49       AC C3ZRY1.1
#=GS G7JET4_MEDTR/205-253    AC G7JET4.1
#=GS B6KKQ9_TOXGO/274-321    AC B6KKQ9.1
#=GS E7F8I0_DANRE/179-229    AC E7F8I0.1
#=GS H2MU97_ORYLA/446-492    AC H2MU97.1
#=GS C2IUJ7_VIBCL/60-110     AC C2IUJ7.1
#=GS H2RN59_TAKRU/123-170    AC H2RN59.1
#=GS G6DC02_DANPL/69-114     AC G6DC02.1
#=GS G3WZJ4_SARHA/228-281    AC G3WZJ4.1
#=GS Q3TBJ0_MOUSE/231-277    AC Q3TBJ0.1
#=GS D3BI36_POLPA/878-922    AC D3BI36.1
#=GS ADO3_ARATH/523-571      AC Q9C9W9.1
#=GS G1SFN8_RABIT/127-174    AC G1SFN8.1
#=GS MDE6_SCHPO/313-368      AC O13730.2
#=GS D2W2E6_NAEGR/480-524    AC D2W2E6.1
#=GS G3QWG1_GORGO/127-174    AC G3QWG1.1
#=GS D9XZ45_9ACTO/287-333    AC D9XZ45.1
#=GS E1GGQ5_LOALO/13-59      AC E1GGQ5.1
#=GS B9TSM5_VIBCL/60-110     AC B9TSM5.1
#=GS D6EWM0_STRLI/287-333    AC D6EWM0.1
#=GS D7L3U2_ARALL/184-228    AC D7L3U2.1
#=GS B8B6M1_ORYSI/439-484    AC B8B6M1.1
#=GS Q2PQA6_IPONI/527-576    AC Q2PQA6.2
#=GS Q9N3K6_CAEEL/250-304    AC Q9N3K6.4
#=GS Q0V6K4_PHANO/296-341    AC Q0V6K4.2
#=GS D1K1C9_9BACE/207-258    AC D1K1C9.1
#=GS C3Y6T2_BRAFL/406-452    AC C3Y6T2.1
#=GS H2QBP4_PANTR/295-349    AC H2QBP4.1
#=GS A9TQY8_PHYPA/367-412    AC A9TQY8.1
#=GS H3DIP0_TETNG/208-252    AC H3DIP0.1
#=GS D2H3W7_AILME/12-64      AC D2H3W7.1
#=GS A8K403_HUMAN/30-82      AC A8K403.1
#=GS D3ZU48_RAT/229-288      AC D3ZU48.1
#=GS I1IGC2_BRADI/315-363    AC I1IGC2.1
#=GS G6ZTD1_VIBCL/256-318    AC G6ZTD1.1
#=GS G1MIV3_AILME/231-290    AC G1MIV3.1
#=GS G6DC02_DANPL/12-62      AC G6DC02.1
#=GS F7BC57_CIOIN/453-498    AC F7BC57.2
#=GS Q2M0L4_DROPS/237-299    AC Q2M0L4.1
#=GS F6YWZ1_XENTR/226-272    AC F6YWZ1.1
#=GS G7A3X0_VIBCL/60-110     AC G7A3X0.1
#=GS F1S6K3_PIG/65-124       AC F1S6K3.1
#=GS F9APY4_VIBCL/256-318    AC F9APY4.1
#=GS Q10G19_ORYSJ/328-376    AC Q10G19.1
#=GS H1QRG3_9ACTO/287-333    AC H1QRG3.1
#=GS B9PET0_POPTR/198-243    AC B9PET0.1
#=GS C1FF12_MICSR/277-326    AC C1FF12.1
#=GS B4DYA4_HUMAN/100-147    AC B4DYA4.1
#=GS H2MBZ2_ORYLA/179-231    AC H2MBZ2.1
#=GS D8SGH9_SELML/270-316    AC D8SGH9.1
#=GS F7G0N8_MACMU/127-174    AC F7G0N8.1
#=GS A2P7A7_VIBCL/256-318    AC A2P7A7.1
#=GS A5GFR1_PIG/127-174      AC A5GFR1.1
#=GS I1CIA7_RHIO9/63-107     AC I1CIA7.1
#=GS Q01IG2_ORYSA/235-292    AC Q01IG2.1
#=GS Q54DR2_DICDI/624-669    AC Q54DR2.1
#=GS G1QWW7_NOMLE/127-174    AC G1QWW7.1
#=GS D7M627_ARALL/184-228    AC D7M627.1
#=GS Q640Y8_XENLA/229-275    AC Q640Y8.1
#=GS B4QRP4_DROSI/237-299    AC B4QRP4.1
#=GS C6RWJ2_VIBCL/256-318    AC C6RWJ2.1
#=GS B9T305_RICCO/36-81      AC B9T305.1
#=GS FK119_ARATH/281-326     AC Q9FHS6.1
#=GS H0ZBB5_TAEGU/297-351    AC H0ZBB5.1
#=GS G7AE79_VIBCL/60-110     AC G7AE79.1
#=GS RABEK_MOUSE/38-90       AC Q8VCH5.2
#=GS F1SUS5_PIG/231-277      AC F1SUS5.1
#=GS Q7T0L8_XENLA/175-226    AC Q7T0L8.1
#=GS D2GZD0_AILME/127-174    AC D2GZD0.1
#=GS H3BWT9_TETNG/199-244    AC H3BWT9.1
#=GS G3HR72_CRIGR/127-174    AC G3HR72.1
#=GS G3I8S0_CRIGR/30-82      AC G3I8S0.1
#=GS Q58D25_BOVIN/127-174    AC Q58D25.1
#=GS A2ZF69_ORYSI/412-461    AC A2ZF69.1
#=GS C3R804_9BACE/207-258    AC C3R804.1
#=GS A3GW53_VIBCL/60-110     AC A3GW53.1
#=GS E6ZHY5_DICLA/204-242    AC E6ZHY5.1
#=GS C3Y0B6_BRAFL/177-231    AC C3Y0B6.1
#=GS B9HQ70_POPTR/262-310    AC B9HQ70.1
#=GS H2KW89_ORYSJ/412-461    AC H2KW89.1
#=GS Q9H863_HUMAN/295-349    AC Q9H863.1
#=GS BSL3_ARATH/335-383      AC Q9SHS7.2
#=GS G1QG03_MYOLU/33-85      AC G1QG03.1
#=GS B0BMQ5_XENTR/123-170    AC B0BMQ5.1
#=GS C7ABG8_9PERO/78-123     AC C7ABG8.1
#=GS D8RGL3_SELML/52-97      AC D8RGL3.1
#=GS A2AUF7_MOUSE/30-82      AC A2AUF7.1
#=GS D2YUR8_VIBMI/60-111     AC D2YUR8.1
#=GS G3GRV0_CRIGR/295-349    AC G3GRV0.1
#=GS E4ZUC7_LEPMJ/299-344    AC E4ZUC7.1
#=GS F4JTC8_ARATH/179-233    AC F4JTC8.1
#=GS A4S6T4_OSTLU/252-312    AC A4S6T4.1
#=GS Q69ZY9_MOUSE/386-431    AC Q69ZY9.1
#=GS H9GFN8_ANOCA/95-148     AC H9GFN8.1
#=GS DYHA_CHLRE/242-287      AC Q39610.2
#=GS B9DFZ9_ARATH/346-394    AC B9DFZ9.1
#=GS F9C7K0_VIBCL/256-318    AC F9C7K0.1
#=GS G3W8W5_SARHA/231-277    AC G3W8W5.1
#=GS D7KTY2_ARALL/255-306    AC D7KTY2.1
#=GS D8T597_SELML/250-296    AC D8T597.1
#=GS I1ER38_AMPQE/92-138     AC I1ER38.1
#=GS F6WMY4_MACMU/50-109     AC F6WMY4.1
#=GS G3UZG5_MOUSE/238-292    AC G3UZG5.1
#=GS G7TT25_VIBCL/256-318    AC G7TT25.1
#=GS H0VY93_CAVPO/30-82      AC H0VY93.1
#=GS B3NCS7_DROER/237-299    AC B3NCS7.1
#=GS D3BTW1_POLPA/43-94      AC D3BTW1.1
#=GS A6AAX6_VIBCL/256-318    AC A6AAX6.1
#=GS F6Y220_HORSE/30-82      AC F6Y220.1
#=GS G7AYJ7_VIBCL/256-318    AC G7AYJ7.1
#=GS F4PX99_DICFS/141-192    AC F4PX99.1
#=GS F7D4B0_ORNAN/263-317    AC F7D4B0.1
#=GS Q4RGQ9_TETNG/31-77      AC Q4RGQ9.1
#=GS H2ZPI2_CIOSA/14-64      AC H2ZPI2.1
#=GS I1EEN6_AMPQE/12-68      AC I1EEN6.1
#=GS A6XSM5_VIBCL/60-110     AC A6XSM5.1
#=GS I1EH79_AMPQE/73-119     AC I1EH79.1
#=GS G1TB68_RABIT/41-90      AC G1TB68.1
#=GS C1BJY1_OSMMO/30-77      AC C1BJY1.1
#=GS F7A7N9_CIOIN/139-183    AC F7A7N9.2
#=GS Q7T0L8_XENLA/123-170    AC Q7T0L8.1
#=GS G3T4W1_LOXAF/33-82      AC G3T4W1.1
#=GS A8PB65_BRUMA/12-60      AC A8PB65.1
#=GS G7PZX8_MACFA/261-315    AC G7PZX8.1
#=GS C3Y4D4_BRAFL/69-114     AC C3Y4D4.1
#=GS F7IB88_CALJA/127-174    AC F7IB88.1
#=GS TEA1_SCHPO/187-237      AC P87061.1
#=GS A1EML8_VIBCL/256-318    AC A1EML8.1
#=GS Q7XQF7_ORYSJ/235-292    AC Q7XQF7.2
#=GS G3SPX3_LOXAF/231-277    AC G3SPX3.1
#=GS G6ZTD1_VIBCL/60-110     AC G6ZTD1.1
#=GS G5BF23_HETGA/111-170    AC G5BF23.1
#=GS G5BRU7_HETGA/231-277    AC G5BRU7.1
#=GS D8SBH5_SELML/325-373    AC D8SBH5.1
#=GS H2PTE2_PONAB/30-82      AC H2PTE2.1
#=GS H3A8T9_LATCH/127-174    AC H3A8T9.1
#=GS D0GZF1_VIBMI/60-111     AC D0GZF1.1
#=GS C3NPQ4_VIBCJ/256-318    AC C3NPQ4.1
#=GS B3KUG0_HUMAN/50-109     AC B3KUG0.1
#=GS D0HTD7_VIBCL/256-318    AC D0HTD7.1
#=GS H9EXQ7_MACMU/30-81      AC H9EXQ7.1
#=GS A2DLV0_TRIVA/176-217    AC A2DLV0.1
#=GS G3WES4_SARHA/177-231    AC G3WES4.1
#=GS F7A134_HORSE/231-277    AC F7A134.1
#=GS D4V5F4_BACVU/239-289    AC D4V5F4.1
#=GS I0YWR7_9CHLO/60-108     AC I0YWR7.1
#=GS G4VLQ8_SCHMA/174-218    AC G4VLQ8.1
#=GS G7NEQ9_MACMU/30-82      AC G7NEQ9.1
#=GS G2XER2_VERDV/219-269    AC G2XER2.1
#=GS C6Z128_9BACE/239-289    AC C6Z128.1
#=GS C0PGG9_MAIZE/517-566    AC C0PGG9.1
#=GS H2ZPI1_CIOSA/14-63      AC H2ZPI1.1
#=GS Q17MZ7_AEDAE/183-232    AC Q17MZ7.1
#=GS Q0UYG2_PHANO/500-541    AC Q0UYG2.2
#=GS Q5T1S4_HUMAN/30-82      AC Q5T1S4.1
#=GS G1N686_MELGA/265-318    AC G1N686.2
#=GS F7H8K3_CALJA/30-82      AC F7H8K3.1
#=GS H2UB19_TAKRU/193-237    AC H2UB19.1
#=GS A8J896_CHLRE/142-199    AC A8J896.1
#=GS C3Y0B6_BRAFL/125-172    AC C3Y0B6.1
#=GS C7E146_ALLCE/526-575    AC C7E146.1
#=GS BSL2_ARATH/346-394      AC Q9SJF0.2
#=GS F9BC51_VIBCL/256-318    AC F9BC51.1
#=GS F8ZWJ4_VIBCL/60-110     AC F8ZWJ4.1
#=GS E3TPZ7_HELAN/487-535    AC E3TPZ7.1
#=GS A6XSM5_VIBCL/256-318    AC A6XSM5.1
#=GS F6QAS8_MONDO/410-454    AC F6QAS8.1
#=GS I1PDW9_ORYGL/228-276    AC I1PDW9.1
#=GS F6VRA1_CALJA/174-233    AC F6VRA1.1
#=GS G7BMY0_VIBCL/256-318    AC G7BMY0.1
#=GS D4A902_RAT/307-352      AC D4A902.1
#=GS I1LU05_SOYBN/328-376    AC I1LU05.1
#=GS I1FU57_AMPQE/486-531    AC I1FU57.1
#=GS E3LIN1_CAERE/13-62      AC E3LIN1.1
#=GS G3SSV4_LOXAF/231-290    AC G3SSV4.1
#=GS G4Z963_PHYSP/224-268    AC G4Z963.1
#=GS D8S0V4_SELML/324-372    AC D8S0V4.1
#=GS B8BN16_ORYSI/333-381    AC B8BN16.1
#=GS G7B8B4_VIBCL/211-273    AC G7B8B4.1
#=GS D7KC25_ARALL/5-39       AC D7KC25.1
#=GS I1PH45_ORYGL/137-180    AC I1PH45.1
#=GS F7ETH8_MACMU/231-277    AC F7ETH8.1
#=GS A6ZVZ3_YEAS7/453-507    AC A6ZVZ3.1
#=GS F1Q7L5_DANRE/339-393    AC F1Q7L5.1
#=GS A5F7D0_VIBC3/60-110     AC A5F7D0.1
#=GS F8ZLK5_VIBCL/60-110     AC F8ZLK5.1
#=GS H2LXQ8_ORYLA/496-542    AC H2LXQ8.1
#=GS RABEK_BOVIN/30-82       AC Q5EA50.1
#=GS G1EAN7_POPBA/521-569    AC G1EAN7.1
#=GS Q0JC97_ORYSJ/235-292    AC Q0JC97.1
#=GS D8T5E7_SELML/487-536    AC D8T5E7.1
#=GS I1R0V6_ORYGL/431-480    AC I1R0V6.1
#=GS A7F712_SCLS1/290-336    AC A7F712.1
#=GS E5UWN5_9BACE/192-242    AC E5UWN5.1
#=GS A1EML8_VIBCL/60-110     AC A1EML8.1
#=GS B5HNN3_9ACTO/287-334    AC B5HNN3.1
#=GS Q3UBU7_MOUSE/219-265    AC Q3UBU7.1
#=GS G0RT87_HYPJQ/86-136     AC G0RT87.1
#=GS E0S5S5_ENCIT/251-288    AC E0S5S5.1
#=GS H2MBZ4_ORYLA/120-172    AC H2MBZ4.1
#=GS G1N083_MELGA/231-277    AC G1N083.1
#=GS I1E8X2_AMPQE/98-144     AC I1E8X2.1
#=GS F6WMX8_MACMU/238-292    AC F6WMX8.1
#=GS Q9H863_HUMAN/231-290    AC Q9H863.1
#=GS F8ZLK5_VIBCL/256-318    AC F8ZLK5.1
#=GS E9Q1Z9_MOUSE/307-352    AC E9Q1Z9.1
#=GS F3BI92_PSEHA/241-299    AC F3BI92.1
#=GS A8E601_XENLA/244-291    AC A8E601.1
#=GS Q54S48_DICDI/89-140     AC Q54S48.1
#=GS H8JYH0_VIBCL/60-110     AC H8JYH0.1
#=GS B5VSS5_YEAS6/453-507    AC B5VSS5.1
#=GS H2MBZ1_ORYLA/179-231    AC H2MBZ1.1
#=GS B8ANI2_ORYSI/328-376    AC B8ANI2.1
#=GS E7EQZ8_HUMAN/100-147    AC E7EQZ8.1
#=GS F1PIC5_CANFA/63-115     AC F1PIC5.1
#=GS H0WRB2_OTOGA/231-277    AC H0WRB2.1
#=GS H9G3V0_ANOCA/148-192    AC H9G3V0.1
#=GS D6B7Q7_9ACTO/291-335    AC D6B7Q7.1
#=GS D9XCB8_STRVR/287-333    AC D9XCB8.1
#=GS C8ZIB6_YEAS8/453-507    AC C8ZIB6.1
#=GS G7BX52_VIBCL/256-318    AC G7BX52.1
#=GS D7MPB2_ARALL/280-326    AC D7MPB2.1
#=GS F7A7Z8_CALJA/45-104     AC F7A7Z8.1
#=GS C3NPQ4_VIBCJ/60-110     AC C3NPQ4.1
#=GS G2HHE1_PANTR/295-349    AC G2HHE1.1
#=GS H0YUV7_TAEGU/231-277    AC H0YUV7.1
#=GS A3ERC8_9BACT/301-346    AC A3ERC8.1
#=GS C2I2C0_VIBCL/60-110     AC C2I2C0.1
#=GS H2RN62_TAKRU/13-63      AC H2RN62.1
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C3ZRY1_BRAFL/4-49                  .................p-CAAHAGT..VC............DGKI.FISGG..A...............................................................---V.Y.G..D...F....V.....N.T..M...S...TYD..P..TENQWDNKAVMG.....................
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G3WZJ4_SARHA/228-281               ..................PRSGFSVA.mAP............SGRT.LLFGG..Vcd..........................................................eeeEESI.E.G..D...F....F.....N.D..L...Y...FYD..I..TKNRWFTGQ---lk...................
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D3BI36_POLPA/878-922               .................e-RYGHSTT..IL............GEKM.IVFGG..T...............................................................---N.K.L..K...D....L.....N.D..I...N...ILQ..L..DTNSWMP-----ppss.................
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G8JL41_MOUSE/5-51                  ..................PRVGHSCS..YFppv.....gdaeSGKI.FIVGG..A...............................................................---N.P.N..Q...S....F.....S.D..V...H...TMD..L..A-----------sgcle................
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H2MBZ2_ORYLA/127-174               ..................ARDGHSAC..VL............GKSM.YIFGG..Y...............................................................-EQL.A.D..C...F....S.....N.D..I...H...KLD..T..TAMVWSLINAKG.....................
G0SSY5_VIBMI/60-111                .................a-RNDAAYT..VC............GDRL.YVFSG..Ag............................................................veKGNN.H.P..T...V....L.....M.D..G...Y...VFD..S..KTNCWAQLK---shp..................
E1GHC7_LOALO/13-62                 ..................RRVNHAAV..AL............NDKI.YSFGG..Yc.............................................................sGELY.D.G..S...Q....P.....V.D..V...H...VLD..T..GNYRWRKLS---vq...................
D3B2S2_POLPA/121-166               ..................PRSRHSAS..LV............NNKI.YIYGG..S...............................................................---D.G.S..R...S....F.....N.S..L...Y...VLD..L..STMRWSIPNC--ng...................
F6U1D7_MACMU/30-82                 ..................ARVGHSCS..YLppv.....gnakTGKV.FIVGG..A...............................................................---N.P.N..R...S....F.....S.D..V...H...AMD..L..GKHQWDLVTCKG.....................
H2ZPI0_CIOSA/18-67                 ..................RRVNHAAV..IV............DHRI.FMFGG..Yc.............................................................mGEDY.K.Q..Q...R....P.....I.D..V...H...VFN..T..YSYRWKK-----iisk.................
C5Y3X8_SORBI/521-570               ................pr-LDHVAVS..LP............CGRI.IIFGG..S...............................................................IAGL.H.S..P...A....Q.....L.F..L...I...DPA..E..EKPTWRILNVPG.....................
F6WMY4_MACMU/114-168               ..................PRSGFSVA.mAP............NHQT.LFFGG..Vcd..........................................................eeeEESL.A.G..E...F....F.....N.D..L...Y...FYD..A..TRNRWFEGQLK-k....................
Q16NJ1_AEDAE/86-142                ..................ARSGHRIV..GN............DSAL.YCFGG..Fnpnm......................................................avvnnDDDE.T.S..S...L....F.....Q.E..L...W...KYD..F..IKNEWTLL----mdp..................
G7P3Z0_MACFA/127-174               ..................ARDGHSAC..VL............GKIM.YIFGG..Y...............................................................-EQQ.A.D..C...F....S.....N.D..I...H...KLD..T..STMTWTLICTKG.....................
D7MFQ3_ARALL/164-213               ..........avaisvte--------..LI............DRKI.YVIGG..S...............................................................DTLS.P.L..K...S....P.....S.R.sM...M...VYD..T..DTEMWELRTRP-d....................
G3WZJ5_SARHA/262-315               ..................PRSGFSVA.mAP............SGRT.LLFGG..Vcd..........................................................eeeEESI.E.G..D...F....F.....N.D..L...Y...FYD..I..TKNRWFTGQ---lk...................
A1F187_VIBCL/256-318               .................g-LAGHFFG..EI............DNKI.IVIGG..Ayfigsqd.................................................afikgnlYAHN.G.L..I...K....H.....F.S..S...N...VWI..F..DGKSWENKCQL-d....................
D6M5W0_9ACTO/446-496               .................t-RYPQSSV..LP............DDSV.LVSGG..Se.............................................................dYRGR.G.D..S...N....I.....H.Q..A...R...LYD..T..RTNTFRRVADP-e....................
F6S3K5_CALJA/30-78                 ..................ARVGHSCS..YLppv.....gnakRGKV.FIVGG..A...............................................................---N.P.N..R...S....F.....S.D..V...H...AMD..L..ETRTWT------mp...................
Y1773_VIBCH/256-318                .................g-LAGHFFG..EI............DNKI.IVIGG..Ayfigsqd.................................................afikgnlYAHN.G.L..I...K....H.....F.S..S...N...VWI..F..DGKSWENKCQL-d....................
B4M877_DROVI/237-297               ..................RSGCCIAA..AP............DGKI.YVWGG..Yartsmkk.................................................dldrgitHTDM.F.A..L...D....V.....D.K..N...-...-GS..G..NKYKWSTVKAG-g....................
I1FVA2_AMPQE/109-150               ..................RRYGHACV..AY............GDKI.FMYGG..R...............................................................--ND.D.D..G...S....F.....R.V..M...E...CFD..I..TRSMW-------lk...................
D7KVS5_ARALL/527-575               .................r-LDHVAVS..MP............CGRV.IIFGG..S...............................................................IAGL.H.S..P...S....Q.....L.F..L...I...DPA..E..EKPSWRILNVPG.....................
H2QBP4_PANTR/231-290               ..................RSGCQMSV..TP............QGGI.VVYGG..Yskqrvkk.................................................dvdkgtrHSDM.F.L..L...K....P.....E.D..G...-...--R..E..DKWVWTRMNPSG.....................
E9ITH8_SOLIN/98-144                ..................GRRGHTAL..VH............RGQM.LIYGG..Y...............................................................--QD.L.R..G...S....S.....S.E..L...W...AFH..F..ETESWHLLSS--se...................
#=GC seq_cons                      ...................pssauss..sh............ss+l.hlaGG..h................................................................ttt.t.s..p...h..........s.-..l...h...hhD..h..pphpWpphp........................
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