GenomeNet

Database: Pfam
Entry: Kelch_2
LinkDB: Kelch_2
Original site: Kelch_2 
#=GF ID   Kelch_2
#=GF AC   PF07646.11
#=GF DE   Kelch motif
#=GF AU   Finn RD
#=GF SE   Context Domains
#=GF GA   21.30 21.30;
#=GF TC   21.30 21.30;
#=GF NC   21.20 21.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Repeat
#=GF WK   Kelch_motif
#=GF RN   [1]
#=GF RM   8126718
#=GF RT   Drosophila kelch motif is derived from a common enzyme fold. 
#=GF RA   Bork P, Doolittle RF; 
#=GF RL   J Mol Biol 1994;236:1277-1282.
#=GF RN   [2]
#=GF RM   2002850
#=GF RT   Novel thioether bond revealed by a 1.7 A crystal structure of
#=GF RT   galactose oxidase. 
#=GF RA   Ito N, Phillips SE, Stevens C, Ogel ZB, McPherson MJ, Keen JN,
#=GF RA   Yadav KD, Knowles PF; 
#=GF RL   Nature 1991;350:87-90.
#=GF RN   [3]
#=GF RM   15475350
#=GF RT   Crystal structure of the Kelch domain of human Keap1. 
#=GF RA   Li X, Zhang D, Hannink M, Beamer LJ; 
#=GF RL   J Biol Chem 2004;279:54750-54758.
#=GF DR   INTERPRO; IPR011498;
#=GF DR   SCOP; 1gof; fa;
#=GF CC   The kelch motif was initially discovered in Kelch
#=GF CC   (Swiss:Q04652). In this protein there are six copies of the
#=GF CC   motif.  It has been shown that Swiss:Q04652 is related to
#=GF CC   Galactose Oxidase [1] for which a structure has been solved [2].
#=GF CC   The kelch motif forms a beta sheet.  Several of these sheets
#=GF CC   associate to form a beta propeller structure as found in
#=GF CC   Pfam:PF00064, Pfam:PF00400 and Pfam:PF00415.
#=GF SQ   1399
#=GS F6HAE8_VITVI/332-380      AC F6HAE8.1
#=GS F7DPY2_ORNAN/67-113       AC F7DPY2.1
#=GS K5NLL3_VIBCL/60-110       AC K5NLL3.1
#=GS G6Z7A6_VIBCL/256-318      AC G6Z7A6.1
#=GS RABEK_HUMAN/30-82         AC Q7Z6M1.1
#=GS H2N8X3_PONAB/231-277      AC H2N8X3.1
#=GS G7AE79_VIBCL/256-318      AC G7AE79.1
#=GS K2TGS7_VIBCL/256-318      AC K2TGS7.1
#=GS D2A260_TRICA/12-62        AC D2A260.1
#=GS FBX42_HUMAN/231-277       AC Q6P3S6.1
#=GS D8TFE7_SELML/114-160      AC D8TFE7.1
#=GS J3MH47_ORYBR/494-543      AC J3MH47.1
#=GS I1L1A1_SOYBN/452-503      AC I1L1A1.1
#=GS X6LH38_RETFI/80-128       AC X6LH38.1
#=GS E0W0R9_PEDHC/299-354      AC E0W0R9.1
#=GS F8YZM5_VIBCL/256-318      AC F8YZM5.1
#=GS G7IG65_MEDTR/518-567      AC G7IG65.1
#=GS H3B3K4_LATCH/230-276      AC H3B3K4.1
#=GS K4E059_TRYCR/89-133       AC K4E059.1
#=GS H0V387_CAVPO/231-277      AC H0V387.1
#=GS G3X961_MOUSE/295-349      AC G3X961.1
#=GS A3F4K1_BRAJU/70-117       AC A3F4K1.1
#=GS S9WKC0_9CETA/127-174      AC S9WKC0.1
#=GS F1N1V7_BOVIN/533-580      AC F1N1V7.1
#=GS G7AYJ7_VIBCL/60-110       AC G7AYJ7.1
#=GS F1L6W8_ASCSU/198-237      AC F1L6W8.1
#=GS F6GXH8_VITVI/460-509      AC F6GXH8.1
#=GS M3WBY7_FELCA/127-174      AC M3WBY7.1
#=GS E3LIN1_CAERE/92-138       AC E3LIN1.1
#=GS G3NH48_GASAC/202-240      AC G3NH48.1
#=GS F0ZFQ5_DICPU/218-263      AC F0ZFQ5.1
#=GS F2Y9J4_POPTN/376-427      AC F2Y9J4.1
#=GS W5MMD3_LEPOC/108-153      AC W5MMD3.1
#=GS T1KHK1_TETUR/73-117       AC T1KHK1.1
#=GS M0SR93_MUSAM/324-372      AC M0SR93.1
#=GS L7LU91_9ACAR/11-60        AC L7LU91.1
#=GS X6MNZ0_RETFI/284-331      AC X6MNZ0.1
#=GS M4Q7C3_PICAB/525-574      AC M4Q7C3.1
#=GS M7IWY5_VIBCL/256-318      AC M7IWY5.1
#=GS U5G7U3_POPTR/393-441      AC U5G7U3.1
#=GS G2HEE4_PANTR/127-174      AC G2HEE4.1
#=GS M3ZXA1_XIPMA/127-174      AC M3ZXA1.1
#=GS G2WNS3_YEASK/453-507      AC G2WNS3.1
#=GS K7F2R9_PELSI/127-174      AC K7F2R9.1
#=GS F6H7M2_VITVI/379-421      AC F6H7M2.1
#=GS V4RRZ3_9ROSI/333-381      AC V4RRZ3.1
#=GS H0Z3C2_TAEGU/127-174      AC H0Z3C2.1
#=GS Q4N2C8_THEPA/245-291      AC Q4N2C8.1
#=GS G1TSS6_RABIT/179-233      AC G1TSS6.1
#=GS D8SF38_SELML/51-139       AC D8SF38.1
#=GS H3CAX0_TETNG/98-147       AC H3CAX0.1
#=GS B3L5C2_PLAKH/1535-1580    AC B3L5C2.1
#=GS T1KHK2_TETUR/12-62        AC T1KHK2.1
#=GS W1P673_AMBTC/23-64        AC W1P673.1
#=GS H9GFN8_ANOCA/32-90        AC H9GFN8.1
#=GS L5JQ81_PTEAL/127-174      AC L5JQ81.1
#=GS K7LTX5_SOYBN/329-377      AC K7LTX5.1
#=GS H3DA96_TETNG/202-244      AC H3DA96.1
#=GS F2Y9J4_POPTN/441-490      AC F2Y9J4.1
#=GS M0TUD0_MUSAM/234-281      AC M0TUD0.1
#=GS M4DVN8_BRARP/182-226      AC M4DVN8.1
#=GS G7JET4_MEDTR/205-253      AC G7JET4.1
#=GS J1ZK28_VIBCL/60-110       AC J1ZK28.1
#=GS E7F8I0_DANRE/179-229      AC E7F8I0.1
#=GS H2MU97_ORYLA/446-492      AC H2MU97.1
#=GS L8TDP9_VIBCL/60-110       AC L8TDP9.1
#=GS H2RN59_TAKRU/123-170      AC H2RN59.1
#=GS I1JWM9_SOYBN/176-222      AC I1JWM9.1
#=GS G3WZJ4_SARHA/228-281      AC G3WZJ4.1
#=GS M1A5G1_SOLTU/325-373      AC M1A5G1.1
#=GS M6YJ37_9LEPT/255-305      AC M6YJ37.1
#=GS W8C5K4_CERCA/237-295      AC W8C5K4.1
#=GS M7KKQ3_VIBCL/60-110       AC M7KKQ3.1
#=GS G3QWG1_GORGO/127-174      AC G3QWG1.1
#=GS I1CB51_RHIO9/144-186      AC I1CB51.1
#=GS W7J3Q9_PLAFA/248-295      AC W7J3Q9.1
#=GS M7G5I3_VIBCL/256-318      AC M7G5I3.1
#=GS K4DAP9_SOLLC/326-374      AC K4DAP9.1
#=GS A0A024VGY3_PLAFA/248-295  AC A0A024VGY3.1
#=GS K5JL42_VIBCL/256-318      AC K5JL42.1
#=GS M7GMS6_VIBCL/42-92        AC M7GMS6.1
#=GS Q55F00_DICDI/354-405      AC Q55F00.1
#=GS Q4S2E2_TETNG/77-121       AC Q4S2E2.1
#=GS Q0V6K4_PHANO/296-341      AC Q0V6K4.2
#=GS W1PI88_AMBTC/516-565      AC W1PI88.1
#=GS V6K0L0_STRRC/286-330      AC V6K0L0.1
#=GS U3JDH3_FICAL/127-174      AC U3JDH3.1
#=GS D2H3W7_AILME/12-64        AC D2H3W7.1
#=GS J1BV06_VIBCL/42-92        AC J1BV06.1
#=GS I1L1A1_SOYBN/520-569      AC I1L1A1.1
#=GS I1IGC2_BRADI/315-363      AC I1IGC2.1
#=GS I6WZC5_SOLTU/325-373      AC I6WZC5.1
#=GS M4DR01_BRARP/493-540      AC M4DR01.1
#=GS G6ZTD1_VIBCL/256-318      AC G6ZTD1.1
#=GS G6DC02_DANPL/12-62        AC G6DC02.1
#=GS F0Z8C8_DICPU/424-468      AC F0Z8C8.1
#=GS F6YWZ1_XENTR/226-272      AC F6YWZ1.1
#=GS G7A3X0_VIBCL/60-110       AC G7A3X0.1
#=GS U3EDS9_CALJA/127-174      AC U3EDS9.1
#=GS F9APY4_VIBCL/256-318      AC F9APY4.1
#=GS H1QRG3_9ACTO/287-333      AC H1QRG3.1
#=GS D8SGH9_SELML/270-316      AC D8SGH9.1
#=GS F7G0N8_MACMU/127-174      AC F7G0N8.1
#=GS V4LZI9_EUTSA/123-167      AC V4LZI9.1
#=GS I1CIA7_RHIO9/63-107       AC I1CIA7.1
#=GS W4G0E9_9STRA/376-421      AC W4G0E9.1
#=GS J1G248_VIBCL/256-318      AC J1G248.1
#=GS A0A024WHD7_PLAFA/248-295  AC A0A024WHD7.1
#=GS V4K8R5_EUTSA/253-304      AC V4K8R5.1
#=GS Q640Y8_XENLA/229-275      AC Q640Y8.1
#=GS L8PB22_STRVR/269-315      AC L8PB22.1
#=GS V4UK68_9ROSI/459-510      AC V4UK68.1
#=GS R0LA12_ANAPL/199-260      AC R0LA12.1
#=GS FK119_ARATH/281-326       AC Q9FHS6.1
#=GS K5UBN1_VIBCL/256-318      AC K5UBN1.1
#=GS G7AE79_VIBCL/60-110       AC G7AE79.1
#=GS A0A016UCJ0_9BILA/114-159  AC A0A016UCJ0.1
#=GS RABEK_MOUSE/38-90         AC Q8VCH5.2
#=GS T1EVR6_HELRO/420-470      AC T1EVR6.1
#=GS Q7T0L8_XENLA/175-226      AC Q7T0L8.1
#=GS D3ZU48_RAT/139-198        AC D3ZU48.2
#=GS L8RN27_VIBCL/60-110       AC L8RN27.1
#=GS W4IY87_PLAFP/248-295      AC W4IY87.1
#=GS S4AMA3_9ACTO/446-496      AC S4AMA3.1
#=GS H3BWT9_TETNG/199-244      AC H3BWT9.1
#=GS S9PNP2_SCHOY/187-237      AC S9PNP2.1
#=GS A2ZF69_ORYSI/412-461      AC A2ZF69.1
#=GS V7AZ23_PHAVU/600-649      AC V7AZ23.1
#=GS L8SQX3_VIBCL/238-300      AC L8SQX3.1
#=GS A3GW53_VIBCL/60-110       AC A3GW53.1
#=GS E6ZHY5_DICLA/204-242      AC E6ZHY5.1
#=GS M1B080_SOLTU/63-111       AC M1B080.1
#=GS Q7T0L8_XENLA/73-118       AC Q7T0L8.1
#=GS L8T3D1_VIBCL/256-318      AC L8T3D1.1
#=GS K5NC85_VIBCL/256-318      AC K5NC85.1
#=GS Q9H863_HUMAN/295-349      AC Q9H863.1
#=GS A0A016X7K7_VIBCL/256-318  AC A0A016X7K7.1
#=GS G1QG03_MYOLU/33-85        AC G1QG03.1
#=GS J1C0Q0_VIBCL/238-300      AC J1C0Q0.1
#=GS A0A023EZQ3_TRIIF/443-488  AC A0A023EZQ3.1
#=GS C7ABG8_9PERO/78-123       AC C7ABG8.1
#=GS K4BMI1_SOLLC/205-251      AC K4BMI1.1
#=GS D2YUR8_VIBMI/60-111       AC D2YUR8.1
#=GS W4X1B8_ATTCE/68-114       AC W4X1B8.1
#=GS F4JTC8_ARATH/179-233      AC F4JTC8.1
#=GS A4S6T4_OSTLU/252-312      AC A4S6T4.1
#=GS M0RIU1_MUSAM/49-105       AC M0RIU1.1
#=GS U6CVW6_NEOVI/231-277      AC U6CVW6.1
#=GS W5FZS9_WHEAT/149-197      AC W5FZS9.1
#=GS U1HKS1_ENDPU/132-178      AC U1HKS1.1
#=GS M7KNU7_VIBCL/60-110       AC M7KNU7.1
#=GS U3IGC9_ANAPL/295-349      AC U3IGC9.1
#=GS C3YDG5_BRAFL/374-418      AC C3YDG5.1
#=GS V6HUQ4_9LEPT/307-350      AC V6HUQ4.1
#=GS Z7LPI8_VIBCL/256-318      AC Z7LPI8.1
#=GS A2ZS74_ORYSJ/21-66        AC A2ZS74.1
#=GS A2EYS7_TRIVA/161-201      AC A2EYS7.1
#=GS F1NL86_CHICK/297-350      AC F1NL86.2
#=GS D8T597_SELML/250-296      AC D8T597.1
#=GS Q4WIA6_ASPFU/298-343      AC Q4WIA6.1
#=GS D7M9B7_ARALL/18-58        AC D7M9B7.1
#=GS I1ER38_AMPQE/92-138       AC I1ER38.1
#=GS S7UP60_TOXGO/274-321      AC S7UP60.1
#=GS F6WMY4_MACMU/50-109       AC F6WMY4.1
#=GS G3UZG5_MOUSE/238-292      AC G3UZG5.1
#=GS A0A023GJ22_9ACAR/169-231  AC A0A023GJ22.1
#=GS D3BTW1_POLPA/43-94        AC D3BTW1.1
#=GS A6AAX6_VIBCL/256-318      AC A6AAX6.1
#=GS F6Y220_HORSE/30-82        AC F6Y220.1
#=GS D8TFK4_SELML/244-290      AC D8TFK4.1
#=GS Q4RGQ9_TETNG/31-77        AC Q4RGQ9.1
#=GS U9UV38_RHIID/33-79        AC U9UV38.1
#=GS I1FD97_AMPQE/13-68        AC I1FD97.1
#=GS C1BJY1_OSMMO/30-77        AC C1BJY1.1
#=GS K5QJB7_VIBCL/256-318      AC K5QJB7.1
#=GS G7PZX8_MACFA/261-315      AC G7PZX8.1
#=GS S7P2V0_MYOBR/127-174      AC S7P2V0.1
#=GS A1EML8_VIBCL/256-318      AC A1EML8.1
#=GS A0A024TDL8_9STRA/28-71    AC A0A024TDL8.1
#=GS L1IA53_GUITH/180-229      AC L1IA53.1
#=GS Q7XQF7_ORYSJ/235-292      AC Q7XQF7.2
#=GS W5Q6K8_SHEEP/513-560      AC W5Q6K8.1
#=GS G5BF23_HETGA/111-170      AC G5BF23.1
#=GS G5BRU7_HETGA/231-277      AC G5BRU7.1
#=GS T1KHH6_TETUR/226-272      AC T1KHH6.1
#=GS M7H9U4_VIBCL/60-110       AC M7H9U4.1
#=GS I3MDN6_SPETR/127-174      AC I3MDN6.1
#=GS G3U206_LOXAF/76-123       AC G3U206.1
#=GS V4UAC7_9ROSI/384-425      AC V4UAC7.1
#=GS C3NPQ4_VIBCJ/256-318      AC C3NPQ4.1
#=GS B3KUG0_HUMAN/50-109       AC B3KUG0.1
#=GS H9EXQ7_MACMU/30-81        AC H9EXQ7.1
#=GS A2DLV0_TRIVA/176-217      AC A2DLV0.1
#=GS B8NFT0_ASPFN/298-343      AC B8NFT0.1
#=GS U4U9L6_DENPD/198-244      AC U4U9L6.1
#=GS G4VLQ8_SCHMA/174-218      AC G4VLQ8.1
#=GS K3XVW2_SETIT/531-580      AC K3XVW2.1
#=GS L8S244_VIBCL/60-110       AC L8S244.1
#=GS M7KTH9_VIBCL/256-318      AC M7KTH9.1
#=GS A0A015NIK5_9GLOM/24-73    AC A0A015NIK5.1
#=GS Q5T1S4_HUMAN/30-82        AC Q5T1S4.1
#=GS H2VY09_CAEJA/91-137       AC H2VY09.2
#=GS C0SE39_PARBP/170-213      AC C0SE39.1
#=GS H2NRQ7_PONAB/223-277      AC H2NRQ7.2
#=GS U3IGC9_ANAPL/229-290      AC U3IGC9.1
#=GS C3Y0B6_BRAFL/125-172      AC C3Y0B6.1
#=GS D8KWE2_ZONAL/75-122       AC D8KWE2.1
#=GS BSL2_ARATH/346-394        AC Q9SJF0.2
#=GS U3JL00_FICAL/232-278      AC U3JL00.1
#=GS F9BC51_VIBCL/256-318      AC F9BC51.1
#=GS H2WD59_CAEJA/740-787      AC H2WD59.2
#=GS F8ZWJ4_VIBCL/60-110       AC F8ZWJ4.1
#=GS M7GMS6_VIBCL/238-300      AC M7GMS6.1
#=GS E3TPZ7_HELAN/487-535      AC E3TPZ7.1
#=GS K7G180_PELSI/231-277      AC K7G180.1
#=GS I1PDW9_ORYGL/228-276      AC I1PDW9.1
#=GS F6VRA1_CALJA/174-233      AC F6VRA1.1
#=GS M7F4Q4_VIBCL/256-318      AC M7F4Q4.1
#=GS M7U0I3_BOTF1/420-463      AC M7U0I3.1
#=GS U3EKJ0_CALJA/231-290      AC U3EKJ0.1
#=GS E3LIN1_CAERE/13-62        AC E3LIN1.1
#=GS E7A2H1_SPORE/637-682      AC E7A2H1.1
#=GS K5P1R2_VIBCL/256-318      AC K5P1R2.1
#=GS J9PBL7_CANFA/231-277      AC J9PBL7.1
#=GS J9PVN1_NICAT/469-520      AC J9PVN1.1
#=GS M6QF44_9LEPT/306-349      AC M6QF44.1
#=GS B8BN16_ORYSI/333-381      AC B8BN16.1
#=GS W5JCG1_ANODA/100-156      AC W5JCG1.1
#=GS D7KC25_ARALL/5-39         AC D7KC25.1
#=GS F7ETH8_MACMU/231-277      AC F7ETH8.1
#=GS F2D1N3_HORVD/555-604      AC F2D1N3.1
#=GS J1VHH0_VIBCL/60-110       AC J1VHH0.1
#=GS A5F7D0_VIBC3/60-110       AC A5F7D0.1
#=GS L5LMA5_MYODS/30-82        AC L5LMA5.1
#=GS K5LRE3_VIBCL/256-318      AC K5LRE3.1
#=GS F8ZLK5_VIBCL/60-110       AC F8ZLK5.1
#=GS J1EZM8_VIBCL/60-110       AC J1EZM8.1
#=GS G1EAN7_POPBA/521-569      AC G1EAN7.1
#=GS Q0JC97_ORYSJ/235-292      AC Q0JC97.1
#=GS L8R6Z8_VIBCL/60-110       AC L8R6Z8.1
#=GS D8T5E7_SELML/487-536      AC D8T5E7.1
#=GS M2R5U3_CERS8/141-183      AC M2R5U3.1
#=GS A1EML8_VIBCL/60-110       AC A1EML8.1
#=GS M7HBT1_VIBCL/60-110       AC M7HBT1.1
#=GS S7P2V0_MYOBR/179-233      AC S7P2V0.1
#=GS F6WMX8_MACMU/238-292      AC F6WMX8.1
#=GS Q9H863_HUMAN/231-290      AC Q9H863.1
#=GS M1BRQ0_SOLTU/537-586      AC M1BRQ0.1
#=GS W9R647_9ROSA/466-517      AC W9R647.1
#=GS B2GNL1_DANRE/30-83        AC B2GNL1.1
#=GS B5VSS5_YEAS6/453-507      AC B5VSS5.1
#=GS H2MBZ1_ORYLA/179-231      AC H2MBZ1.1
#=GS J9PVN1_NICAT/534-583      AC J9PVN1.1
#=GS L7FFY9_9ACTO/287-332      AC L7FFY9.1
#=GS B9RAN1_RICCO/235-291      AC B9RAN1.1
#=GS U3IHU3_ANAPL/536-582      AC U3IHU3.1
#=GS R1CNV6_EMIHU/334-379      AC R1CNV6.1
#=GS D9XCB8_STRVR/287-333      AC D9XCB8.1
#=GS U6LPN7_9EIME/44-91        AC U6LPN7.1
#=GS M7L092_VIBCL/60-110       AC M7L092.1
#=GS L8SQX3_VIBCL/42-92        AC L8SQX3.1
#=GS D7MPB2_ARALL/280-326      AC D7MPB2.1
#=GS A1CYV4_NEOFI/298-343      AC A1CYV4.1
#=GS N0CVG9_9ACTO/292-336      AC N0CVG9.1
#=GS B9ILX1_POPTR/327-378      AC B9ILX1.2
#=GS U6CVZ1_NEOVI/275-329      AC U6CVZ1.1
#=GS W1NEZ6_AMBTC/331-379      AC W1NEZ6.1
#=GS R7V2S1_CAPTE/12-68        AC R7V2S1.1
#=GS K5ME45_VIBCL/256-318      AC K5ME45.1
#=GS D7FKT7_ECTSI/323-370      AC D7FKT7.1
#=GS A3ERC8_9BACT/301-346      AC A3ERC8.1
#=GS M7M6V3_VIBCL/60-110       AC M7M6V3.1
#=GS H2MVY2_ORYLA/239-285      AC H2MVY2.1
#=GS M7JHX6_VIBCL/60-110       AC M7JHX6.1
#=GS B9ILX1_POPTR/392-441      AC B9ILX1.2
#=GS C0PKL8_MAIZE/127-173      AC C0PKL8.1
#=GS U5FPT8_POPTR/184-230      AC U5FPT8.1
#=GS C7GSG4_YEAS2/453-507      AC C7GSG4.1
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F6HAE8_VITVI/332-380                 .....................................PRYQHAAV..FV............NA.RL.HVSGG..A..............................................................lGG..GR.M.V..E...D....S.....S..S..V...A...V.L...D..T..AAGVWCDTK---sv...................
F7DPY2_ORNAN/67-113                  .....................................PMAGHSSC..VI............ED.KM.IVFGG..S...............................................................--..LG.S.R..Q...M....S.....N..D..V...W...V.L...D..L..EQWAWSKPNVS-g....................
K5NLL3_VIBCL/60-110                  ....................................a-RNDAAYT..VC............GN.KL.YVFSG..Ag............................................................ieGN..NS.F.P..T...V....L.....M..D..G...Y...V.F...D..S..QINQWKRLE---rt...................
G6Z7A6_VIBCL/256-318                 ....................................g-LAGHFFG..EI............DN.KI.IVIGG..Ayfigsqd.................................................afikgnlYA..HN.G.L..I...K....H.....F..S..S...N...V.W...I..F..DGKSWENKCQL-d....................
RABEK_HUMAN/30-82                    .....................................ARVGHSCS..YLppv.....gnakRG.KV.FIVGG..A...............................................................--..-N.P.N..R...S....F.....S..D..V...H...T.M...D..L..GKHQWDLDTCKG.....................
H2N8X3_PONAB/231-277                 .....................................PMAGHSSC..VI............DD.KM.IVFGG..S...............................................................--..LG.S.R..Q...M....S.....N..D..V...W...V.L...D..L..EQWAWSKPN---isg..................
G7AE79_VIBCL/256-318                 ....................................g-LAGHFFG..EI............DN.KI.IVIGG..Ayfigsqd.................................................afikgnlYA..HN.G.L..I...K....H.....F..S..S...N...V.W...I..F..DGKSWENKCQL-d....................
K2TGS7_VIBCL/256-318                 ....................................g-LAGHFFG..EI............DN.KI.IVIGG..Ayfigsqd.................................................afikgnlYA..HN.G.L..I...K....H.....F..S..S...N...V.W...I..F..DGKSWENKCQL-d....................
D2A260_TRICA/12-62                   ....................................k-RVNHAAV..AV............GH.KI.YSFGG..Yc.............................................................tGE..DS.K.A..Y...T....S.....M..D..V...H...V.L...N..T..TTFRWTKHP---vsd..................
FBX42_HUMAN/231-277                  .....................................PMAGHSSC..VI............DD.KM.IVFGG..S...............................................................--..LG.S.R..Q...M....S.....N..D..V...W...V.L...D..L..EQWAWSKPN---isg..................
D8TFE7_SELML/114-160                 .....................................PRDIHTCS..SY............KN.CC.IVMGG..E...............................................................--..DG.G.N..A...Y....L.....Y..D..V...H...I.L...D..T..ETMAWREVK---ttg..................
J3MH47_ORYBR/494-543                 ...................................pr-LDHVAVS..LP............GG.RV.LIFGG..S...............................................................VA..GL.H.S..A...S....Q.....L..Y..L...L...D.P...T..E..EKPTWRILNVPG.....................
I1L1A1_SOYBN/452-503                 .....................................RLGHTLSV..YG............GR.KI.LMFGG..La............................................................ksGA..LR.F.R..S...S....D.....V..F..T...M...D.L...S..E..EEPCWRCVTGSG.....................
X6LH38_RETFI/80-128                  ....................................p-LDGYAYV..CI............ND.II.LFFGG..Q..............................................................yYK..NN.N.N..I...V....S.....K..S..V...H...K.Y...S..I..QGKKWTT-----fkdi.................
E0W0R9_PEDHC/299-354                 ....................................pRSGCSIAV..GP............NN.KA.YTFGG..Vvde.........................................................eesEE..DI.C.G..T...F....L.....N..D..F...N...V.L...D..L..ERRTWKPGTLLG.....................
F8YZM5_VIBCL/256-318                 ....................................g-LAGHFFG..EI............DN.KI.IVIGG..Ayfigsqd.................................................afikgnlYA..HN.G.L..I...K....H.....F..S..S...N...V.W...I..F..DGKSWENKCQL-d....................
G7IG65_MEDTR/518-567                 ...................................pr-LDHVAVS..LP............GG.RI.LIFGG..S...............................................................VA..GL.H.S..A...S....Q.....L..Y..I...L...D.P...T..D..EKPTWRILNVPG.....................
H3B3K4_LATCH/230-276                 .....................................PMAGHSSS..VI............GD.KM.IVFGG..S...............................................................--..LG.S.R..Q...M....S.....N..E..V...W...V.L...D..L..EQWAWSKP----nitc.................
K4E059_TRYCR/89-133                  .....................................GRANHSAI..MH............EK.RM.IIFGG..H...............................................................--..-R.N.L..E...V....F.....D..D..M...Y...L.V...N..L..ETMRWEKVN---ye...................
H0V387_CAVPO/231-277                 .....................................PMAGHSSC..VI............DD.KM.IVFGG..S...............................................................--..LG.S.R..Q...M....S.....S..D..V...W...V.L...D..L..EQWAWSKPNV--tg...................
G3X961_MOUSE/295-349                 ....................................a-RSGFSVA.vAP............NH.QI.LVFGG..Vcd..........................................................eeeEE..SL.E.G..S...F....F.....S..D..L...Y...I.Y...D..S..AKSRWF------aaqlkg...............
A3F4K1_BRAJU/70-117                  .....................................GRSSHGIA..VI............GD.KL.YSFGG..E...............................................................-Y..DT.N.V..G...I....D.....N..D..L...H...V.F...D..F..NTQTWSIAPAKG.....................
S9WKC0_9CETA/127-174                 .....................................ARDGHSAC..VL............GK.TM.YIFGG..Y...............................................................-E..QL.A.D..C...F....S.....N..D..I...H...K.L...D..T..STMTWTLICTKG.....................
F1N1V7_BOVIN/533-580                 ...............................ghgepg------IA..VL............DS.RI.YVLGG..R...............................................................-S..HN.R.G..S...R....T.....G..Y..V...H...I.Y...D..A..GRDRWEEGPQL-d....................
G7AYJ7_VIBCL/60-110                  ....................................a-RNDAAYT..VC............GN.KL.YVFSG..Ag............................................................ieGN..NS.F.P..T...V....L.....M..D..G...Y...V.F...D..S..QINQWKRLE---rt...................
F1L6W8_ASCSU/198-237                 ....................................k-LASHSAS..IV............GD.SM.IVFGG..S...............................................................--..-M.G.N..C...S....S.....N..E..I...W...V.L...D..I..PGRVW-------l....................
F6GXH8_VITVI/460-509                 ...................................pr-LDHVAVS..LP............GG.RI.LIFGG..S...............................................................VA..GL.H.S..A...S....Q.....L..Y..L...L...D.P...T..D..EKPTWRILNVPG.....................
M3WBY7_FELCA/127-174                 .....................................ARDGHSAC..VL............GK.TM.YIFGG..Y...............................................................-E..QL.A.D..C...F....S.....N..D..I...H...K.L...D..T..STMTWTLICTKG.....................
E3LIN1_CAERE/92-138                  ....................................q-RYGHTAV..EY............NG.KA.YVWGG..R...............................................................--..ND.D.Y..G...A....C.....N..L..M...H...E.Y...D..P..AKNMWRKVE---idg..................
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H2RN60_TAKRU/121-168                 .....................................ARDGHSAC..VL............LK.SM.YIFGG..Y...............................................................-E..QL.A.D..C...F....S.....N..D..I...H...K.L...D..T..TTMVWSLINAKG.....................
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K2WSB6_VIBCL/60-110                  ....................................a-RNDAAYT..VC............GN.KL.YVFSG..Ag............................................................ieGN..NS.F.P..T...V....L.....M..D..G...Y...V.F...D..S..QINQWKRLE---rt...................
U6CRC2_NEOVI/30-82                   .....................................ARVGHSCS..YLppv.....gdakSG.KV.FIVGG..A...............................................................--..-D.P.H..R...S....F.....S..D..V...H...I.L...D..L..GTYRWDLAA---veg..................
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M7I4C6_VIBCL/256-318                 ....................................g-LAGHFFG..EI............DN.KI.IVIGG..Ayfigsqd.................................................afikgnlYA..HN.G.L..I...K....H.....F..S..S...N...V.W...I..F..DGKSWENKCQL-d....................
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I1MGZ0_SOYBN/460-509                 ...................................pr-LDHVAVS..LP............GG.RI.LIFGG..S...............................................................VA..GL.H.S..A...S....Q.....L..Y..I...L...D.P...T..D..EKPTWRILNVPG.....................
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G3UZ63_MOUSE/264-318                 ....................................a-RSGFSVA.vAP............NH.QI.LVFGG..Vcd..........................................................eeeEE..SL.E.G..S...F....F.....S..D..L...Y...I.Y...D..S..AKSRWF------aaqlkg...............
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J1L008_VIBCL/60-110                  ....................................a-RNDAAYT..VC............GN.KL.YVFSG..Ag............................................................ieGN..NS.F.P..T...V....L.....M..D..G...Y...V.F...D..S..QINQWKRLE---rt...................
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H2RN62_TAKRU/68-115                  .....................................ARDGHSAC..VL............LK.SM.YIFGG..Y...............................................................-E..QL.A.D..C...F....S.....N..D..I...H...K.L...D..T..TTMVWSLINAKG.....................
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G1EAN1_POPBA/392-441                 ...................................pr-LDHVAVS..LP............GG.RI.LIFGG..S...............................................................VA..GL.H.S..A...S....Q.....L..Y..L...L...D.P...T..D..EKPTWRILNVPG.....................
A5GFR4_PIG/13-59                     .....................................RRVNHAAV..AV............GH.RV.YSFGG..Yc.............................................................sGE..DY.E.T..L...R....Q.....I..D..V...H...I.F...N..A..DTHKWS------tp...................
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J9PWI0_NICAT/532-581                 ...................................pr-LDHVAVT..MP............CG.RI.IIFGG..S...............................................................IA..GL.H.S..P...S....Q.....L..F..L...L...D.P...S..E..EKPLWRTLNVPG.....................
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H9FW55_MACMU/231-290                 .....................................RSGCQMSV..TP............QG.GI.VIYGG..Yskqrvkk.................................................dvdkgtrHS..DM.F.L..L...K....P.....E..D..G...-...-.-...R..E..DKWVWTRMNPSG.....................
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U9UID6_RHIID/33-79                   .....................................PRSGHTAT..LI............GD.KI.YFIGG..Y...............................................................--..-N.F.S..I...S....Pk...eS..D..V...F...Y.Y...D..G..NKLAWVEVN---sq...................
Q6C2P9_YARLI/252-296                 ...................................qv--YGHSST..TV............GA.KI.FSFGG..T...............................................................--..-N.G.A..Q...C....T.....N..D..M...Y...C.F...N..T..DAHTLKK-----idrs.................
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E4Z4D4_OIKDI/63-109                  .....................................ARYQSSVA..ML............NN.IL.YVFGG..Y...............................................................--..VD.S.L..T...A....L.....N..D..S...W...Y.F...S..P..KKETWDRVVC--sk...................
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I1HQ19_BRADI/280-332                 ...........................pvpcsltcgr------LL..NL............GE.KL.VMVGG..I...............................................................AK..HN.R.P..D...I....I.....K..G..I...G...I.W...E..L..DKKQWQEVGRMP.....................
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K5P1R2_VIBCL/60-110                  ....................................a-RNDAAYT..VC............GN.KL.YVFSG..Ag............................................................ieGN..NS.F.P..T...V....L.....M..D..G...Y...V.F...D..S..QINQWKRLE---rt...................
R0LAW3_ANAPL/127-174                 .....................................ARDGHSAC..VL............AK.SM.FIFGG..Y...............................................................-E..QL.A.D..C...F....S.....N..D..I...H...K.L...D..T..TNMMWTLISAKG.....................
C5IFV3_HORVU/450-501                 .....................................RLGHTLSV..YG............GR.KI.LMFGG..La............................................................ksGP..LK.F.R..S...S....D.....V..F..T...M...D.L...S..E..EEPCWRCVTGSG.....................
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K7FHC9_PELSI/32-79                   .....................................ARVGHNCL..YLpsg.....ptagKG.QV.VIVGG..A...............................................................--..-D.P.S..G...S....F.....S..D..A...H...I.I...D..L..DRHQWS------m....................
M0THX5_MUSAM/477-526                 ...................................pr-LDHVAVS..LP............GG.RI.LIFGG..S...............................................................VA..GL.H.S..A...S....Q.....L..Y..L...L...D.P...T..E..EKPTWRILNVPG.....................
A8PB65_BRUMA/5-53                    ....................................k-RVNHAAV..AL............ND.QI.YSFGG..Yc.............................................................sGE..LY.D.G..S...Q....P.....V..D..V...H...V.L...D..T..GNYRWRKLT---v....................
A0A016UD33_9BILA/114-159             .....................................PRAYHGAV..LC............NE.KM.IIFGG..F...............................................................--..-N.G.R..E...Y....F.....Q..H..A...K...L.F...D..L..NKKNWEYVTNM-h....................
H2MBZ2_ORYLA/127-174                 .....................................ARDGHSAC..VL............GK.SM.YIFGG..Y...............................................................-E..QL.A.D..C...F....S.....N..D..I...H...K.L...D..T..TAMVWSLINAKG.....................
K5TA77_VIBCL/256-318                 ....................................g-LAGHFFG..EI............DN.KI.IVIGG..Ayfigsqd.................................................afikgnlYA..HN.G.L..I...K....H.....F..S..S...N...V.W...I..F..DGKSWENKCQL-d....................
W5LQ86_ASTMX/127-174                 .....................................ARDGHSAC..VL............GK.SM.YIFGG..Y...............................................................-E..QL.A.D..C...F....S.....N..D..I...H...K.L...D..T..TTMSWSLINA--tg...................
G0SSY5_VIBMI/60-111                  ....................................a-RNDAAYT..VC............GD.RL.YVFSG..Ag............................................................veKG..NN.H.P..T...V....L.....M..D..G...Y...V.F...D..S..KTNCWAQLK---shp..................
F6U1D7_MACMU/30-82                   .....................................ARVGHSCS..YLppv.....gnakTG.KV.FIVGG..A...............................................................--..-N.P.N..R...S....F.....S..D..V...H...A.M...D..L..GKHQWDLVTCKG.....................
H2ZPI0_CIOSA/18-67                   .....................................RRVNHAAV..IV............DH.RI.FMFGG..Yc.............................................................mGE..DY.K.Q..Q...R....P.....I..D..V...H...V.F...N..T..YSYRWKK-----iisk.................
Q16NJ1_AEDAE/86-142                  .....................................ARSGHRIV..GN............DS.AL.YCFGG..Fnpnm......................................................avvnnDD..DE.T.S..S...L....F.....Q..E..L...W...K.Y...D..F..IKNEWTLL----mdp..................
G7P3Z0_MACFA/127-174                 .....................................ARDGHSAC..VL............GK.IM.YIFGG..Y...............................................................-E..QQ.A.D..C...F....S.....N..D..I...H...K.L...D..T..STMTWTLICTKG.....................
G3WZJ5_SARHA/262-315                 .....................................PRSGFSVA.mAP............SG.RT.LLFGG..Vcd..........................................................eeeEE..SI.E.G..D...F....F.....N..D..L...Y...F.Y...D..I..TKNRWFTGQ---lk...................
D6M5W0_STRSH/446-496                 ....................................t-RYPQSSV..LP............DD.SV.LVSGG..Se.............................................................dYR..GR.G.D..S...N....I.....H..Q..A...R...L.Y...D..T..RTNTFRRVADP-e....................
F6S3K5_CALJA/30-78                   .....................................ARVGHSCS..YLppv.....gnakRG.KV.FIVGG..A...............................................................--..-N.P.N..R...S....F.....S..D..V...H...A.M...D..L..ETRTWT------mp...................
V4M6C2_EUTSA/34-81                   .....................................PRSSHAVA..VV............GD.KL.YSFGG..E...............................................................-L..TS.N.V..P...I....D.....K..D..L...H...V.F...D..L..NTHTWSIAP---atg..................
J3PX82_PUCT1/110-156                 .....................................PRQQHSAL..RL............GE.KM.FVFGG..V...............................................................--..DG.Q.T..S...K....L.....C..D..M...W...A.L...D..L..LSYAWYEVACEG.....................
I1FVA2_AMPQE/109-150                 .....................................RRYGHACV..AY............GD.KI.FMYGG..R...............................................................--..ND.D.D..G...S....F.....R..V..M...E...C.F...D..I..TRSMW-------lk...................
H2QBP4_PANTR/231-290                 .....................................RSGCQMSV..TP............QG.GI.VVYGG..Yskqrvkk.................................................dvdkgtrHS..DM.F.L..L...K....P.....E..D..G...-...-.-...R..E..DKWVWTRMNPSG.....................
E9ITH8_SOLIN/98-144                  .....................................GRRGHTAL..VH............RG.QM.LIYGG..Y...............................................................--..QD.L.R..G...S....S.....S..E..L...W...A.F...H..F..ETESWHLLSS--se...................
#=GC seq_cons                        ......................................pssauss..hh............ss.+l.hlaGG..t................................................................t..tt.t.s..p...h..........p..c..l...h...s.h...D..h..pphpWpphp........................
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