GenomeNet

Database: Pfam
Entry: L27_2
LinkDB: L27_2
Original site: L27_2 
#=GF ID   L27_2
#=GF AC   PF09045.5
#=GF DE   L27_2
#=GF AU   Mistry J, Sammut SJ
#=GF SE   pdb_1y76
#=GF GA   20.90 20.90;
#=GF TC   21.00 21.40;
#=GF NC   20.00 18.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   L27_domain
#=GF RN   [1]
#=GF RM   15863617
#=GF RT   A unified assembly mode revealed by the structures of tetrameric
#=GF RT   L27 domain complexes formed by mLin-2/mLin-7 and Patj/Pals1
#=GF RT   scaffold proteins. 
#=GF RA   Feng W, Long JF, Zhang M; 
#=GF RL   Proc Natl Acad Sci U S A. 2005;102:6861-6866.
#=GF DR   INTERPRO; IPR015132;
#=GF CC   The L27_2 domain is a protein-protein interaction domain capable
#=GF CC   of organising scaffold proteins into supramolecular assemblies
#=GF CC   by formation of heteromeric L27_2 domain complexes. L27_2
#=GF CC   domain-mediated protein assemblies have been shown to play
#=GF CC   essential roles in cellular processes including asymmetric cell
#=GF CC   division, establishment and maintenance of cell polarity, and
#=GF CC   clustering of receptors and ion channels. Members of this family
#=GF CC   form specific heterotetrameric complexes, in which each domain
#=GF CC   contains three alpha-helices. The two N-terminal helices of each
#=GF CC   L27_2 domain pack together to form a tight, four-helix bundle in
#=GF CC   the heterodimer, whilst the third helix of each L27_2 domain
#=GF CC   forms another four-helix bundle that assembles the two units of
#=GF CC   the heterodimer into a tetramer [1].
#=GF SQ   113
#=GS F6T1W3_MACMU/7-64     AC F6T1W3.1
#=GS G1S7E0_NOMLE/6-63     AC G1S7E0.1
#=GS H2XN51_CIOIN/6-63     AC H2XN51.1
#=GS A7SRG3_NEMVE/6-63     AC A7SRG3.1
#=GS F7HHK2_CALJA/6-63     AC F7HHK2.1
#=GS F7C8K6_CALJA/6-63     AC F7C8K6.1
#=GS H2PS57_PONAB/6-63     AC H2PS57.1
#=GS Q1LXN3_DANRE/12-69    AC Q1LXN3.2
#=GS D4A2W4_RAT/6-63       AC D4A2W4.1
#=GS G1JT17_CHICK/6-63     AC G1JT17.1
#=GS MPDZ_HUMAN/6-63       AC O75970.2
#=GS E1C4T3_CHICK/8-65     AC E1C4T3.1
#=GS MPDZ_RAT/6-63         AC O55164.1
#=GS F1MAD2_RAT/8-65       AC F1MAD2.1
#=GS G3UJR8_LOXAF/7-64     AC G3UJR8.1
#=GS Q3TUR5_MOUSE/84-141   AC Q3TUR5.1
#=GS F8WGE8_MOUSE/6-63     AC F8WGE8.1
#=GS H3AIS3_LATCH/6-63     AC H3AIS3.1
#=GS G5AP53_HETGA/6-63     AC G5AP53.1
#=GS E1BLF1_BOVIN/8-65     AC E1BLF1.2
#=GS G3NFP8_GASAC/6-63     AC G3NFP8.1
#=GS H2LIZ8_ORYLA/2-56     AC H2LIZ8.1
#=GS F1MMT3_BOVIN/21-78    AC F1MMT3.2
#=GS G1RY01_NOMLE/8-65     AC G1RY01.1
#=GS D3ZKZ2_RAT/8-65       AC D3ZKZ2.1
#=GS INADL_MOUSE/8-65      AC Q63ZW7.2
#=GS INADL_MOUSE/8-65      DR PDB; 3UIT A; 8-65;
#=GS INADL_MOUSE/8-65      DR PDB; 3UIT C; 9-65;
#=GS INADL_MOUSE/8-65      DR PDB; 3UIT B; 9-65;
#=GS INADL_MOUSE/8-65      DR PDB; 3UIT D; 8-65;
#=GS G3TKC2_LOXAF/6-63     AC G3TKC2.1
#=GS H2LHB5_ORYLA/6-63     AC H2LHB5.1
#=GS G1SLR4_RABIT/7-64     AC G1SLR4.1
#=GS H2N775_PONAB/8-65     AC H2N775.1
#=GS H3J2N7_STRPU/190-247  AC H3J2N7.1
#=GS F7FYD6_CALJA/6-63     AC F7FYD6.1
#=GS F7I9N8_CALJA/8-65     AC F7I9N8.1
#=GS A2ADS8_MOUSE/8-65     AC A2ADS8.1
#=GS A2ADL9_MOUSE/8-65     AC A2ADL9.1
#=GS G1NGL1_MELGA/8-65     AC G1NGL1.1
#=GS G3QRZ2_GORGO/10-67    AC G3QRZ2.1
#=GS G9K5R4_MUSPF/8-65     AC G9K5R4.1
#=GS B3S1C8_TRIAD/1-58     AC B3S1C8.1
#=GS F7DEH9_MONDO/6-63     AC F7DEH9.1
#=GS H2LES7_ORYLA/9-66     AC H2LES7.1
#=GS F6S559_HORSE/10-67    AC F6S559.1
#=GS G3Q7B3_GASAC/6-63     AC G3Q7B3.1
#=GS F1N9G0_CHICK/1-57     AC F1N9G0.1
#=GS H2RX16_TAKRU/10-67    AC H2RX16.1
#=GS Q4SXL4_TETNG/1-54     AC Q4SXL4.1
#=GS G1S7E1_NOMLE/6-63     AC G1S7E1.1
#=GS G1KH21_ANOCA/8-65     AC G1KH21.1
#=GS F5H1U9_HUMAN/6-63     AC F5H1U9.1
#=GS D3YUX2_MOUSE/6-63     AC D3YUX2.1
#=GS E9QMC3_MOUSE/6-63     AC E9QMC3.1
#=GS G7PSC6_MACFA/7-64     AC G7PSC6.1
#=GS H2YMG8_CIOSA/6-63     AC H2YMG8.1
#=GS D3ZCM0_RAT/6-63       AC D3ZCM0.1
#=GS G1TA76_RABIT/8-65     AC G1TA76.1
#=GS H3CK11_TETNG/47-103   AC H3CK11.1
#=GS G3S205_GORGO/6-63     AC G3S205.1
#=GS H2YMG7_CIOSA/6-63     AC H2YMG7.1
#=GS E7EMF0_HUMAN/8-65     AC E7EMF0.1
#=GS B7ZMI4_HUMAN/6-63     AC B7ZMI4.1
#=GS A8DZE1_DANRE/12-69    AC A8DZE1.1
#=GS Q4SAP7_TETNG/1-58     AC Q4SAP7.1
#=GS G7MHB0_MACMU/8-65     AC G7MHB0.1
#=GS E7EPZ1_HUMAN/6-63     AC E7EPZ1.1
#=GS A2ADS6_MOUSE/8-65     AC A2ADS6.1
#=GS E2QYC9_CANFA/8-65     AC E2QYC9.1
#=GS G1KL12_ANOCA/10-67    AC G1KL12.1
#=GS H9G1B4_MACMU/6-63     AC H9G1B4.1
#=GS F8W8T2_HUMAN/8-65     AC F8W8T2.1
#=GS Q3UGL9_MOUSE/8-65     AC Q3UGL9.1
#=GS F6RHB2_MONDO/6-63     AC F6RHB2.1
#=GS MPDZ_MOUSE/6-63       AC Q8VBX6.2
#=GS G7NFZ9_MACMU/7-64     AC G7NFZ9.1
#=GS H0WLW5_OTOGA/8-65     AC H0WLW5.1
#=GS F7DF31_MONDO/8-65     AC F7DF31.1
#=GS D2HP61_AILME/1-58     AC D2HP61.1
#=GS F7IC03_CALJA/8-65     AC F7IC03.1
#=GS D3ZI45_RAT/8-65       AC D3ZI45.1
#=GS D3ZWH6_RAT/8-65       AC D3ZWH6.1
#=GS H2R430_PANTR/6-63     AC H2R430.1
#=GS F6REK9_XENTR/5-62     AC F6REK9.1
#=GS B2RQR2_MOUSE/6-63     AC B2RQR2.1
#=GS F7CPH6_CALJA/8-65     AC F7CPH6.1
#=GS A5PKX9_HUMAN/8-65     AC A5PKX9.1
#=GS G3WB42_SARHA/6-63     AC G3WB42.1
#=GS G5BSM7_HETGA/8-65     AC G5BSM7.1
#=GS F7FV02_MONDO/6-63     AC F7FV02.1
#=GS H0WTI1_OTOGA/6-63     AC H0WTI1.1
#=GS D2H2X4_AILME/6-63     AC D2H2X4.1
#=GS F6ZZY6_HORSE/8-65     AC F6ZZY6.1
#=GS H2N774_PONAB/8-65     AC H2N774.1
#=GS H0VDJ5_CAVPO/7-64     AC H0VDJ5.1
#=GS F1PGC1_CANFA/6-63     AC F1PGC1.1
#=GS F6T1X2_MACMU/7-64     AC F6T1X2.1
#=GS F1PGB9_CANFA/6-63     AC F1PGB9.1
#=GS F1QUF9_DANRE/8-65     AC F1QUF9.1
#=GS G3PTR0_GASAC/11-62    AC G3PTR0.1
#=GS G1L4U6_AILME/6-63     AC G1L4U6.1
#=GS F7IC28_CALJA/8-65     AC F7IC28.1
#=GS H2YMG6_CIOSA/6-63     AC H2YMG6.1
#=GS F7DEI7_MONDO/8-65     AC F7DEI7.1
#=GS G3T0Y3_LOXAF/8-65     AC G3T0Y3.1
#=GS G1LYY8_AILME/8-65     AC G1LYY8.1
#=GS INADL_HUMAN/8-65      AC Q8NI35.3
#=GS INADL_HUMAN/8-65      DR PDB; 1VF6 B; 10-65;
#=GS INADL_HUMAN/8-65      DR PDB; 1VF6 A; 12-65;
#=GS G1P3E1_MYOLU/7-64     AC G1P3E1.1
#=GS H2PZ54_PANTR/8-65     AC H2PZ54.1
#=GS F6QSL1_XENTR/6-63     AC F6QSL1.1
#=GS H3D171_TETNG/10-67    AC H3D171.1
#=GS G1P825_MYOLU/8-65     AC G1P825.1
#=GS H2ZX49_LATCH/5-62     AC H2ZX49.1
#=GS G3GZE2_CRIGR/1-56     AC G3GZE2.1
#=GS F8W8B3_HUMAN/8-65     AC F8W8B3.1
#=GS G3X2X5_SARHA/8-65     AC G3X2X5.1
F6T1W3_MACMU/7-64                ....DKNRALQAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
G1S7E0_NOMLE/6-63                ....DKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQG-n.....
H2XN51_CIOIN/6-63                elek----AALIIKRIQNQLKRQGDYSNDAELEAMKSLMESPLFKKMAQLQASIQQLKKEV-v.....
A7SRG3_NEMVE/6-63                ....ETSRVVQILDGFQRKLESQGDYDNGEDLERIKAMLKSPLFHQLLAVQQSLRELNTQ--yh....
F7HHK2_CALJA/6-63                ....DKNRALQAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
F7C8K6_CALJA/6-63                ....DKNRALQAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
H2PS57_PONAB/6-63                ....DKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
Q1LXN3_DANRE/12-69               ....ERQQVLQALERLQSKLVQREEWTHSDRLGTLKEALQSPLFSHILTLQHSVKQLKDQLN......
D4A2W4_RAT/6-63                  ....DKNRALQAAERLQSKLKERGDVANEDKLSLLKSVLQSPLFSQILSLQTSLQQLKDQVN......
G1JT17_CHICK/6-63                ....DTHRALQAVERLQAKLRDRGDIANEEKLNLLKSVLQSPLFNQILNLQTSVQQLRDQVN......
MPDZ_HUMAN/6-63                  ....DKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
E1C4T3_CHICK/8-65                ....DKQQVLQIIDRLQAKLREKRDVQHNENLSVLRNTLRSPLFNQILTLQQSIKQLKDQLN......
MPDZ_RAT/6-63                    ....DKNRALQAAERLQSKLKERGDVANEDKLSLLKSVLQSPLFSQILSLQTSLQQLKDQVN......
F1MAD2_RAT/8-65                  ....EKMQVLQVLDRLRGKLQEKGDTTQNEKLSAFYETLKSPLFNQILTLQQSIKQLKGQLS......
G3UJR8_LOXAF/7-64                ....DKNRALRAAERLQAKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQNLKEQV-d.....
Q3TUR5_MOUSE/84-141              ....DKNRALQAAERLQSKLKERGDVANEDKLSLLKSVLQSPLFSQILNLQTSLQQLKDQV-g.....
F8WGE8_MOUSE/6-63                ....DKNRALQAAERLQSKLKERGDVANEDKLSLLKSVLQSPLFSQILNLQTSLQQLKDQVN......
H3AIS3_LATCH/6-63                ....DTQRALQAVERLQAKLRDCGDAANEEKLSLLKSVLQSPLFNQILNLQSSVQQLRDQM-m.....
G5AP53_HETGA/6-63                ....DKNRALQAAERLQAKLRERGDVANEDKLSLLKSVLQSPLFSQILNLQASVQQLKDQVN......
E1BLF1_BOVIN/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSLFYETLKSPLFNQILTLQQSIKQLKGQLS......
G3NFP8_GASAC/6-63                ....ERQQVVGALERLRAKLVQREDWTHSETLGNLSETLQSPLFSHILTLQHSIQQLRSQLN......
H2LIZ8_ORYLA/2-56                ....DTQCALEAVERLQAKLKERGETPTQDKLSLLKTVLQSPLFLHILSLQES---------qrnppa
F1MMT3_BOVIN/21-78               ....DKNRALQAAERLQAKLRERGDAANEDKLNLLKSVLQSPLFSQILNFQTSIQQLKDQVN......
G1RY01_NOMLE/8-65                ....DKLQVLQVLDRLKMKLQEKGDMSQNEKLSMFYETLKSPLFNQILTLQQSIKQLKGQLN......
D3ZKZ2_RAT/8-65                  ....EKMQVLQVLDRLRGKLQEKGDTTQNEKLSAFYETLKSPLFNQILTLQQSIKQLKGQLS......
INADL_MOUSE/8-65                 ....EKMQVLQVLDRLRGKLQEKGDTTQNEKLSAFYETLKSPLFNQILTLQQSIKQLKGQLS......
#=GR INADL_MOUSE/8-65      SS    ....--CHHHHHHHHHHHHHHHHT--TTHHHHHHHHHHHH-HHHHHHHHHHHH-TTB-S-CT......
G3TKC2_LOXAF/6-63                ....DKNRALRAAERLQAKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQNLKEQV-d.....
H2LHB5_ORYLA/6-63                ....DTQRALQAVERLQAKLKERGEVPTEEKLSLLKSVLQSPLFHQILALQKSVQHLKEQVN......
G1SLR4_RABIT/7-64                ....DKNRALQAAERLQAKLRERGDVANEDKLSLLKSVLQSPLFSQILNLQTSMQQLKDQVN......
H2N775_PONAB/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSMFYETLKSPLFNQILTLQQSIKQLKGQLN......
H3J2N7_STRPU/190-247             ....DTQRAVSVLQGLQGRLVAAGEPELGEQFASMIDLLASPSFRHLLNLQQSVRELKHHI-d.....
F7FYD6_CALJA/6-63                ....DKNRALQAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
F7I9N8_CALJA/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSVFYETLKSPLFNQILTLQQSIKQLKGQLN......
A2ADS8_MOUSE/8-65                ....EKMQVLQVLDRLRGKLQEKGDTTQNEKLSAFYETLKSPLFNQILTLQQSIKQLKGQLS......
A2ADL9_MOUSE/8-65                ....EKMQVLQVLDRLRGKLQEKGDTTQNEKLSAFYETLKSPLFNQILTLQQSIKQLKGQLS......
G1NGL1_MELGA/8-65                ....DKQQVLQIIDRLQAKLREKRDVQHNENLTVLRNTLRSPLFNQILTLQQSIKQLKDQLN......
G3QRZ2_GORGO/10-67               ....DKNRALHAAQRLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
G9K5R4_MUSPF/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSLFYETLKSPLFNQILTLQQSIRQLKGQLS......
B3S1C8_TRIAD/1-58                ....DTSRALAVLSKFHNKLKTDGFESHAQNLSKVRDMLQHPVFGHLLNMQSSMGDM-----iekvc.
F7DEH9_MONDO/6-63                ....DTSRALQAAERLQVKLRERGDVANEDKLSLLKSVLQSPLFSQILNLQTSVQQLKDQVN......
H2LES7_ORYLA/9-66                ....ERQQVLGALERLRAKLVQREEWTHSDRLANLQVALQSPLFSHILTLQHSIKQLRDQLS......
F6S559_HORSE/10-67               ....DKNRALQAAERLQAKLRERGDVANEDKLNLLKSVLQSPLFSQILNLQTSVQQLKEQVN......
G3Q7B3_GASAC/6-63                ....DTQRALQAVERLQAKLKERGEVPTEEKLSLLKSVLQSPLFHQILALQKSVQHLRDQV-k.....
F1N9G0_CHICK/1-57                ....-THRALQAVERLQAKLRDRGDIANEEKLNLLKSVLQSPLFNQILNLQTSVQQLRDQVN......
H2RX16_TAKRU/10-67               ....DTQRALQAVERLQAKLKERGEVPTEEKLNLLRSVLQSPLFHQILALQKSVQHLRDQ--th....
Q4SXL4_TETNG/1-54                ....----VLGALERLQTKLVQREEWSHSGAVGTLRQTLQSPLLSHILTLQQSIRQLRNQL-t.....
G1S7E1_NOMLE/6-63                ....DKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQG-n.....
G1KH21_ANOCA/8-65                ....DKQQVLQILEHLLMKLHERGDTSHSENLAFLYNTLKNPLFNHMLTLQQSIKQLKEQL-t.....
F5H1U9_HUMAN/6-63                ....DKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
D3YUX2_MOUSE/6-63                ....DKNRALQAAERLQSKLKERGDVANEDKLSLLKSVLQSPLFSQILNLQTSLQQLKDQVN......
E9QMC3_MOUSE/6-63                ....DKNRALQAAERLQSKLKERGDVANEDKLSLLKSVLQSPLFSQILNLQTSLQQLKDQVN......
G7PSC6_MACFA/7-64                ....DKNRALQAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
H2YMG8_CIOSA/6-63                .ele---KAAVVLKRLQNQLKRQGDYSHDAELDAMKSLMESPLFKKMVQLQASIQQLKK---eas...
D3ZCM0_RAT/6-63                  ....DKNRALQAAERLQSKLKERGDVANEDKLSLLKSVLQSPLFSQILSLQTSLQQLKDQVN......
G1TA76_RABIT/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSVFCETLRSPLFNQILTLQQSIKQLKGQLS......
H3CK11_TETNG/47-103              ..vt---SVLGALERLQTKLVQREEWSHSGAVGTLRQTLQSPLLSHILTLQQSIRQLRNQL-t.....
G3S205_GORGO/6-63                ....DKNRALHAAQRLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
H2YMG7_CIOSA/6-63                .ele---KAAVVLKRLQNQLKRQGDYSHDAELDAMKSLMESPLFKKMVQLQASIQQLKK---eas...
E7EMF0_HUMAN/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSMFYETLKSPLFNQILTLQQSIKQLKGQLN......
B7ZMI4_HUMAN/6-63                ....DKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
A8DZE1_DANRE/12-69               ....ERQQVLQALERLQSKLVQREEWTHSDRLGTLKEALQSPLFSHILTLQHSVKQLKDQV-m.....
Q4SAP7_TETNG/1-58                ....DTQRALQAVERLQARLKERGEVPTEEKLSLLRSVLQSPLFHQILALQKSVQHLRDQVN......
G7MHB0_MACMU/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSVFYETLKSPLFNQILTLQQSIKQLKGQLN......
E7EPZ1_HUMAN/6-63                ....DKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
A2ADS6_MOUSE/8-65                ....EKMQVLQVLDRLRGKLQEKGDTTQNEKLSAFYETLKSPLFNQILTLQQSIKQLKGQLS......
E2QYC9_CANFA/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSLFYETLQSPLFNQILTLQQSIKQLKGQLS......
G1KL12_ANOCA/10-67               ....DTHRALQAVERLQVKLRERGDTSNEEKLSLLKSVLQSPLFNQILNLQICLPQSRDQVN......
H9G1B4_MACMU/6-63                ....DKNRALQAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
F8W8T2_HUMAN/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSMFYETLKSPLFNQILTLQQSIKQLKGQLN......
Q3UGL9_MOUSE/8-65                ....EKMQVLQVLDRLRGKLQEKGDTTQNEKLSAFYETLKSPLFNQILTLQQSIKQLKGQLS......
F6RHB2_MONDO/6-63                ....DTSRALQAAERLQVKLRERGDVANEDKLSLLKSVLQSPLFSQILNLQTSVQQLKDQVN......
MPDZ_MOUSE/6-63                  ....DKNRALQAAERLQSKLKERGDVANEDKLSLLKSVLQSPLFSQILNLQTSLQQLKDQVN......
G7NFZ9_MACMU/7-64                ....DKNRALQAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
H0WLW5_OTOGA/8-65                ....DKLQVLQVLDRLKGKLQEKGDTSQNEKLSLFYETLRSPLFNQILTLQQSIKQLKGQLS......
F7DF31_MONDO/8-65                ...n-KLQILQVLERLQMKLQDRGDTSQNEKLALFCETLKSPLFNQILTIQQSIRQLKGQLS......
D2HP61_AILME/1-58                ....DKLQVLQVLDRLKMKLQEKGDTSQSEKLSLFYETLRSPLFNQILTLQQSIKQLKGQLS......
F7IC03_CALJA/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSVFYETLKSPLFNQILTLQQSIKQLKGQLN......
D3ZI45_RAT/8-65                  ....EKMQVLQVLDRLRGKLQEKGDTTQNEKLSAFYETLKSPLFNQILTLQQSIKQLKGQLS......
D3ZWH6_RAT/8-65                  ....EKMQVLQVLDRLRGKLQEKGDTTQNEKLSAFYETLKSPLFNQILTLQQSIKQLKGQLS......
H2R430_PANTR/6-63                ....DKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
F6REK9_XENTR/5-62                ....DKAQVLLIAERLQKKLKDKGDLSHHEKMCILRDTLKSPLFNQILTVQQSIKQLKEQVS......
B2RQR2_MOUSE/6-63                ....DKNRALQAAERLQSKLKERGDVANEDKLSLLKSVLQSPLFSQILNLQTSLQQLKDQVN......
F7CPH6_CALJA/8-65                ....DKNRALQAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
A5PKX9_HUMAN/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSMFYETLKSPLFNQILTLQQSIKQLKGQLN......
G3WB42_SARHA/6-63                ....DTSRALQAAERLQAKLRERGDIANEDKLSLLKSVLQSPLFSQILNLQTSVQQLKDQVN......
G5BSM7_HETGA/8-65                ....DKLQVLQVLQRLRAKLQDRGDTSQHSTLSAFCDTLQSPLFTQILALQKSLRQLKGQLS......
F7FV02_MONDO/6-63                ....DTSRALQAAERLQVKLRERGDVANEDKLSLLKSVLQSPLFSQILNLQTSVQQLKDQVN......
H0WTI1_OTOGA/6-63                ....DKNRALQAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILNLQTSVQQLKDQVN......
D2H2X4_AILME/6-63                ....DKNRALQAAERLQAKLRERGDVANEDKLNLLKSVLQSPLFSQILNLQTSVQQLKDQVN......
F6ZZY6_HORSE/8-65                ....DKLQVLQVLDRLKMKLQEKGDASQNEKLSVFYETLKSPLFNQILTLQQSIKQLKGQLS......
H2N774_PONAB/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSMFYETLKSPLFNQILTLQQSIKQLKGQLN......
H0VDJ5_CAVPO/7-64                ....DKNRALQAAERLQAKLRERGDIANEDKLSLLKSVLQSPLFSQILNLQASVQQLKDQVS......
F1PGC1_CANFA/6-63                ....DKNRALQAAERLQAKLRERGDVANEDKLNLLKSVLQSSLFSQILNLQTSVQRLKDQVN......
F6T1X2_MACMU/7-64                ....DKNRALQAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVN......
F1PGB9_CANFA/6-63                ....DKNRALQAAERLQAKLRERGDVANEDKLNLLKSVLQSSLFSQILNLQTSVQRLKDQVN......
F1QUF9_DANRE/8-65                ....ERQQVLQALERLQSKLVQREEWTHSDRLGTLKEALQSPLFSHILTLQHSVKQLKDQLN......
G3PTR0_GASAC/11-62               ....DAQLALEAVERLQAKLKERGEAPTQEKLSLLKTVLQSPLFHNILSLQQA---------qrk...
G1L4U6_AILME/6-63                ....DKNRALQAAERLQAKLRERGDVANEDKLNLLKSVLQSPLFSQILNLQTSVQQLKDQVN......
F7IC28_CALJA/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSVFYETLKSPLFNQILTLQQSIKQLKGQLN......
H2YMG6_CIOSA/6-63                .ele---KAAVVLKRLQNQLKRQGDYSHDAELDAMKSLMESPLFKKMVQLQASIQQLKK---eas...
F7DEI7_MONDO/8-65                ...n-KLQILQVLERLQMKLQDRGDTSQNEKLALFCETLKSPLFNQILTIQQSIRQLKGQLS......
G3T0Y3_LOXAF/8-65                ....DKIQVLQVLERLKMKLQEKGDTSQNEKLSTFYETLRSPLFNQILTLQQSIKQLKGQLS......
G1LYY8_AILME/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQSEKLSLFYETLRSPLFNQILTLQQSIKQLKGQLS......
INADL_HUMAN/8-65                 ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSMFYETLKSPLFNQILTLQQSIKQLKGQLN......
#=GR INADL_HUMAN/8-65      SS    ....XXXHHHHHHHHHHHHHHHCT--TTHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHH......
G1P3E1_MYOLU/7-64                ....DKNRALQAAERLQAKLRERGDVANEDKLNLLKSVLQSPLFSQILNLQTSVQQLKDQVN......
H2PZ54_PANTR/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSMFYETLKSPLFNQILTLQQSIKQLKGQLN......
F6QSL1_XENTR/6-63                ....DTHRALQAVERLQVKVRERGDIANEEKLCLLKSVLQSPLFNQILSLQTSLQHLREQVN......
H3D171_TETNG/10-67               ....DTQRALQAVERLQARLKERGEVPTEEKLSLLRSVLQSPLFHQILALQKSVQHLRDQVN......
G1P825_MYOLU/8-65                ....DKLQVLPILDRLKVKLQEKGDTSQIEKLSMFYETLKSPLFNQILTLQQSIKQLKGQLS......
H2ZX49_LATCH/5-62                ....DKQHVLQAIDRLKTKLREKGDTSQTEKLNILHDTVQSPLFNQILTIQHSIKQLKEQVS......
G3GZE2_CRIGR/1-56                ....--MQVLQVLDRLRMKLQEKGDTTQNEKLSAFYEMLKSPLFNQILTLQQSIKQLKGQLS......
F8W8B3_HUMAN/8-65                ....DKLQVLQVLDRLKMKLQEKGDTSQNEKLSMFYETLKSPLFNQILTLQQSIKQLKGQLN......
G3X2X5_SARHA/8-65                ...n-KLQILQVLERLQMKLHERGDTSQHERLVLFSETLKSPLFNQILTIQQSIKQLKGQLS......
#=GC SS_cons                     ....XXCHHHHHHHHHHHHHHHCT--TTHHHHHHHHHHHH-HHHHHHHHHHHHHCCCHCHCC......
#=GC seq_cons                    ....DKppsLQshERLQsKL+ERGDsupp-KLSlL+ssLQSPLFsQILoLQpSlpQLKcQls......
//
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