GenomeNet

Database: Pfam
Entry: LMP
LinkDB: LMP
Original site: LMP 
#=GF ID   LMP
#=GF AC   PF04778.11
#=GF DE   LMP repeated region
#=GF AU   Kerrison ND
#=GF SE   Pfam-B_2380 (release 7.6)
#=GF GA   26.00 26.00;
#=GF TC   26.80 26.70;
#=GF NC   25.90 25.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   7543881
#=GF RT   Selection of Mycoplasma hominis PG21 deletion mutants by
#=GF RT   cultivation in the presence of monoclonal antibody 552. 
#=GF RA   Jensen LT, Ladefoged S, Birkelund S, Christiansen G; 
#=GF RL   Infect Immun 1995;63:3336-3347.
#=GF DR   INTERPRO; IPR006864;
#=GF CC   This family consists of a repeated sequence element found in the
#=GF CC   LMP group of surface-located membrane proteins of Mycoplasma
#=GF CC   hominis.  The the number of repeats in the protein affects the
#=GF CC   tendency of cells to spontaneously  aggregate.  Agglutination
#=GF CC   may be an important factor in colonisation. Non-agglutinating
#=GF CC   microorganisms might easily be distributed whereas  aggregation
#=GF CC   might provide a better chance to avoid an antibody response
#=GF CC   since some of the epitopes may be buried [1].
#=GF SQ   13
#=GS D1J7V1_MYCHP/966-1125  AC D1J7V1.1
#=GS D1J7V1_MYCHP/809-965   AC D1J7V1.1
#=GS D1J7V1_MYCHP/652-808   AC D1J7V1.1
#=GS D1J8L6_MYCHP/132-286   AC D1J8L6.1
#=GS D1J7J0_MYCHP/206-362   AC D1J7J0.1
#=GS D1J7V1_MYCHP/494-651   AC D1J7V1.1
#=GS S8C103_9LAMI/29-159    AC S8C103.1
#=GS D1J7J0_MYCHP/363-519   AC D1J7J0.1
#=GS D1J7V1_MYCHP/337-493   AC D1J7V1.1
#=GS D1J7J0_MYCHP/834-990   AC D1J7J0.1
#=GS D1J7J0_MYCHP/677-833   AC D1J7J0.1
#=GS D1J7J1_MYCHP/185-329   AC D1J7J1.1
#=GS D1J7J0_MYCHP/520-676   AC D1J7J0.1
D1J7V1_MYCHP/966-1125             .................SANTLLAKLTDKDNTIQQAKTELEKEVQKANQAVASNN...TASMQSAKSSLDAKVTEITKKLETFNKDKDAKFKELEQTRKDIDEFI.KQIENDPqtkkNYQNIVKNLKDKKAEKNSITFSNNKKEIQDANKSLQDELNNAKITKKGITDFYNS-KKQLEDLIK...............
D1J7V1_MYCHP/809-965              .................SANTLLAKLTDKDNTIQQAKTELEKEVQKANQAVASNN...TASMQSAKSSLDAKVTEITKKLETFNKDKDVKFKELEQTRKDIDEFI.NTNKTNP....NYSTLISELTSKRDSKNSVTNSSNKSDIETANTELKQALAKANTDKDQADNLARSTKEQLNKSI-s..............
D1J7V1_MYCHP/652-808              .................NANQLLNKLVDSDKDIQKAKTELSQEIQSASQELNLNN...PTSMQSAKESLDAKVTEITKKLETFNKDKDVKFKELEKTRKDIDEFI.NTNKTNP....NYSTLISELTSKRDSKNSVTNSSNKSDIETANTELKQALAKANTDKAQADNLAKSTKEQLNNSI-s..............
D1J8L6_MYCHP/132-286              ...............vm--RMLDNKLIDNDVDIQKTKKDLNSQIINALEIFNKNN...IDEINNLNKSLTFKISEVEDILIKFKQSKEQEFEKLQKTRKLVEEFLaKDVVKSD....YYANIVRNLNREVSRRGNVSISSNKSEIVAANINLNEVL---KQSKEFVENDMQKLRDSLISLI-v..............
D1J7J0_MYCHP/206-362              .................QANQLLPQLSDNDSEIAKAKKSLDAEIKNANQAVASNN...TASMQSAKSSLDAKVAEITKKLETFNKDKEAKFNELKQTRNQIQEFI.NTNKNNP....NYSELISQLTSKRDSKNSVTDSSNKSDIESANTELKQALAKANADKVQADNLAKSIKEQLNNSV-s..............
D1J7V1_MYCHP/494-651              .................KANTLLPQLNDNDSEIVKAKESLNAEITNANKAVNQND...NASMQSAKSSLDDKVTKIQNQLTEFNKDKDAKFKELEQTRKDIDNFLtDDVKNNP....NYATLVKDLTNAKDDKKSVTKSSNKSEIIAANDELKQALDKAKVAKDQIDEANKSIKEQLSDSI-t..............
S8C103_9LAMI/29-159               .........ialsarin---------------------ALESEISQLRQQLSERDg.fISHLESQLESLDASVIDAEDKLAAAQQEKENLTRENEQLSSAVKKLN.RDVAKLE...iFRKTLMKSLQEDEDSQVSVTNYSSASRLIANNDD-------------------------------dvsnqaqlppedset
D1J7J0_MYCHP/363-519              .................NANTLSAKLTDKDNTIQQAKTELEKEVQKADQAIKSNN...TASMQSAKSSLDAKVAEITKKLETFNKDKEAKFNELKQTRNQIQEFI.NTNKNNP....NYSELISQLTSKRDSKNSVTDSSNKSDIESANTELKQALAKANADKVQADNLAKSIKEQLNNSV-s..............
D1J7V1_MYCHP/337-493              .................NAKEFKKLLIDNDQKIVDLKSNLDNEISKAEQSL-SKD...KESMESANDLLNTKLIEYKEILNKFNQEKEAKFNELEQTRKNIENFLtDEVKNNP....NYATLVKDLTNAKDAKKSVTNSSNKSDIIAANEALIQALADANKAKDQVDEANKSIKEQLNALID...............
D1J7J0_MYCHP/834-990              .................NANTLSAKLTDKDNTIQQAKTELEKEVQKANQAIKSNN...TASMQSAKSSLDAKVAEITKKLETFNKDKEAKFNELKQTRNQIQEFI.NTNKNNP....NYSELISQLTSKRDSKNSVTDSSNKSDIESANTELKQALNTAKAKKSSIDNELRPLKNDLQSKIE...............
D1J7J0_MYCHP/677-833              .................NANTLSAKLTDKDNTIQQAKTELEKEVQKANQAIKSNN...TASMQSAKSSLDAKVAEITKKLETFNKDKEAKFNELKQTRNQIQEFI.NTNKNNP....NYSELISQLTSKRDSKNSVTDSSNKSDIESANTELKQALAKANADKVQADNLAKSIKEQLNNSV-s..............
D1J7J1_MYCHP/185-329              kaiidsepsknvdssre------------------------------LQIFNDSNveaKSTLEDIDKKIDAAIRANNDLNEKIQNYKSAKLSDLESSRNDLSNFI.ANDLKNP....VYKEIADKINEKIKEVKGVGKNSTIKELQAAIKTLADAKEKAIKEKAWIDRV-------------gikkvleiqrs....
D1J7J0_MYCHP/520-676              .................NANTLSAKLTDKDNTIQQAKTELEKEVQKADQAIKSNN...TASMQSAKSWLDAKVAEITKKLETFNKDKEAKFNELKQTRNQIQEFI.NTNKNNP....NYSELISQLTSKRDSKNSVTDSSNKSDIESANTELKQALAKANADKVQADNLAKSIKEQLNNSV-s..............
#=GC seq_cons                     .................sANpL.sKLsDpDssIQpAKo-L-pElppAsQAlsSNN...sASMQSAKSSLDAKVsEITKKLETFNKDKEAKFpELcQTRppIpEFI.sssKNNP....NYupLlspLTsK+DSKNSVTsSSNKSDIpuANsELKQALsKApscKsQsDNhs+SlKEQLsspl.s..............
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