GenomeNet

Database: Pfam
Entry: LOH1CR12
LinkDB: LOH1CR12
Original site: LOH1CR12 
#=GF ID   LOH1CR12
#=GF AC   PF10158.4
#=GF DE   Tumour suppressor protein
#=GF AU   KOGs, Finn RD, Coggill PC
#=GF SE   KOGs (KOG4515)
#=GF GA   23.20 23.20;
#=GF TC   23.30 23.20;
#=GF NC   23.10 23.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11896457
#=GF RT   A detailed transcriptional map of the chromosome 12p12 tumour
#=GF RT   suppressor locus. 
#=GF RA   Montpetit A, Boily G, Sinnett D; 
#=GF RL   Eur J Hum Genet. 2002;10:62-71.
#=GF DR   INTERPRO; IPR018780;
#=GF CC   This is a region of 130 amino acids that is the most conserved
#=GF CC   region of hypothetical proteins involved in loss of
#=GF CC   heterozygosity and thus tumour suppression [1]. The exact
#=GF CC   function is not known.
#=GF SQ   152
#=GS E9BY13_CAPO3/94-225   AC E9BY13.1
#=GS H3FK84_PRIPA/46-173   AC H3FK84.1
#=GS E2BHD6_HARSA/148-276  AC E2BHD6.1
#=GS D9MT74_9MUSC/107-162  AC D9MT74.1
#=GS Q16ZQ2_AEDAE/218-278  AC Q16ZQ2.1
#=GS G7PJV8_MACFA/61-191   AC G7PJV8.1
#=GS B5LFR2_DROSI/196-246  AC B5LFR2.1
#=GS F6JGP5_DROSI/194-244  AC F6JGP5.1
#=GS F7IJ41_CALJA/18-143   AC F7IJ41.1
#=GS G3MRS5_9ACAR/80-210   AC G3MRS5.1
#=GS Q29H95_DROPS/187-318  AC Q29H95.1
#=GS F1PDM0_CANFA/1-124    AC F1PDM0.1
#=GS H9HD41_ATTCE/151-279  AC H9HD41.1
#=GS G3MPH3_9ACAR/113-243  AC G3MPH3.1
#=GS H2VS43_CAEJA/125-293  AC H2VS43.1
#=GS F1LER0_ASCSU/66-211   AC F1LER0.1
#=GS G1LW93_AILME/61-191   AC G1LW93.1
#=GS H3J1M7_STRPU/112-242  AC H3J1M7.1
#=GS F6JGP6_DROSI/194-244  AC F6JGP6.1
#=GS B4L2E2_DROMO/213-344  AC B4L2E2.1
#=GS H9K1A3_APIME/141-269  AC H9K1A3.1
#=GS F6PG67_MONDO/60-190   AC F6PG67.1
#=GS D9MT67_DROMI/107-162  AC D9MT67.1
#=GS D9MT57_DROMI/107-162  AC D9MT57.1
#=GS F6J1X7_DROME/194-244  AC F6J1X7.1
#=GS F7IJ39_CALJA/61-191   AC F7IJ39.1
#=GS B0X6W7_CULQU/191-321  AC B0X6W7.1
#=GS A8WU98_CAEBR/68-220   AC A8WU98.1
#=GS B4YWY4_DROME/187-217  AC B4YWY4.1
#=GS H2R1T3_PANTR/61-191   AC H2R1T3.1
#=GS A9YGP1_DROME/194-244  AC A9YGP1.1
#=GS G1NS04_MELGA/1-74     AC G1NS04.2
#=GS G3WJ41_SARHA/52-182   AC G3WJ41.1
#=GS B3RIX6_TRIAD/60-187   AC B3RIX6.1
#=GS F1NG32_CHICK/1-128    AC F1NG32.1
#=GS B4R391_DROSI/3-74     AC B4R391.1
#=GS G1KCT8_ANOCA/61-191   AC G1KCT8.1
#=GS F6YM09_ORNAN/20-144   AC F6YM09.1
#=GS F6JD79_DROSN/196-236  AC F6JD79.1
#=GS F6JD45_DROYA/196-236  AC F6JD45.1
#=GS D9MT69_9MUSC/107-162  AC D9MT69.1
#=GS F7IJ40_CALJA/8-140    AC F7IJ40.1
#=GS D9MT52_DROAI/107-162  AC D9MT52.1
#=GS L12R1_BOVIN/61-191    AC Q08DP2.1
#=GS G3RZM1_GORGO/61-191   AC G3RZM1.1
#=GS F6YFS9_MACMU/18-143   AC F6YFS9.1
#=GS G3S234_GORGO/8-139    AC G3S234.1
#=GS B4JL73_DROGR/199-330  AC B4JL73.1
#=GS D2A5H3_TRICA/132-262  AC D2A5H3.1
#=GS G1SZM8_RABIT/61-191   AC G1SZM8.1
#=GS L12R1_XENLA/61-191    AC Q5PPY2.1
#=GS D4XWZ8_9MOLU/51-172   AC D4XWZ8.1
#=GS C3Y7G4_BRAFL/27-157   AC C3Y7G4.1
#=GS C1BUN3_9MAXI/100-225  AC C1BUN3.1
#=GS I1G2L4_AMPQE/79-210   AC I1G2L4.1
#=GS A8PQW4_BRUMA/61-192   AC A8PQW4.1
#=GS H2ZJF3_CIOSA/56-186   AC H2ZJF3.1
#=GS E3M4S4_CAERE/66-216   AC E3M4S4.1
#=GS A9YGP9_DROME/194-244  AC A9YGP9.1
#=GS A7UV35_ANOGA/193-323  AC A7UV35.1
#=GS G0PJX7_CAEBE/66-169   AC G0PJX7.1
#=GS B3N1E3_DROAN/199-330  AC B3N1E3.1
#=GS B7PUZ3_IXOSC/77-207   AC B7PUZ3.1
#=GS A3Z3Y6_9SYNE/7-111    AC A3Z3Y6.1
#=GS H2L613_ORYLA/18-143   AC H2L613.1
#=GS B5LFR0_DROSI/196-246  AC B5LFR0.1
#=GS B4YWZ4_DROME/187-231  AC B4YWZ4.1
#=GS H3BGN5_LATCH/61-191   AC H3BGN5.1
#=GS E4YFP3_OIKDI/154-281  AC E4YFP3.1
#=GS F6JD97_DROTE/196-236  AC F6JD97.1
#=GS H2NGM6_PONAB/61-191   AC H2NGM6.1
#=GS B1H257_RAT/61-191     AC B1H257.1
#=GS A9YGP3_DROME/194-244  AC A9YGP3.1
#=GS B5LFP8_DROSI/196-246  AC B5LFP8.1
#=GS A9YGN8_DROME/194-244  AC A9YGN8.1
#=GS L12R1_DANRE/61-181    AC Q5XIX8.1
#=GS D3PHH9_9MAXI/100-225  AC D3PHH9.1
#=GS F6JD90_DROTE/196-236  AC F6JD90.1
#=GS F6JD75_DROSN/196-236  AC F6JD75.1
#=GS F6JGP7_DROSI/194-244  AC F6JGP7.1
#=GS B4YWY1_DROME/187-217  AC B4YWY1.1
#=GS L12R1_CHICK/50-180    AC Q5ZJA9.1
#=GS A7S969_NEMVE/67-200   AC A7S969.1
#=GS E5SUA4_TRISP/41-126   AC E5SUA4.1
#=GS E0W036_PEDHC/143-295  AC E0W036.1
#=GS F6JGQ5_DROSI/194-244  AC F6JGQ5.1
#=GS D5G9I7_TUBMM/160-269  AC D5G9I7.1
#=GS C3Y7G6_BRAFL/36-166   AC C3Y7G6.1
#=GS Q4S181_TETNG/61-191   AC Q4S181.1
#=GS G3P5C9_GASAC/40-170   AC G3P5C9.1
#=GS F1NRC3_CHICK/20-150   AC F1NRC3.1
#=GS F6JD44_DROYA/196-236  AC F6JD44.1
#=GS B4GY33_DROPE/187-318  AC B4GY33.1
#=GS B4YWZ3_DROME/187-217  AC B4YWZ3.1
#=GS F6JD52_DROYA/196-236  AC F6JD52.1
#=GS L12R1_MOUSE/61-191    AC Q9D920.1
#=GS B4Q1I2_DROYA/196-327  AC B4Q1I2.1
#=GS B5LFQ9_DROSI/196-246  AC B5LFQ9.1
#=GS G9K8F1_MUSPF/41-176   AC G9K8F1.1
#=GS F4WS06_ACREC/144-272  AC F4WS06.1
#=GS B4M1I1_DROVI/204-335  AC B4M1I1.1
#=GS H9JNP2_BOMMO/137-197  AC H9JNP2.1
#=GS Q86IZ8_DICDI/148-265  AC Q86IZ8.1
#=GS H3D892_TETNG/61-191   AC H3D892.1
#=GS F6JMB5_DROSI/163-212  AC F6JMB5.1
#=GS F6JMA3_DROSI/163-212  AC F6JMA3.1
#=GS D2H874_AILME/43-173   AC D2H874.1
#=GS H0ZR43_TAEGU/61-194   AC H0ZR43.1
#=GS B4YWY2_DROME/187-217  AC B4YWY2.1
#=GS G3P5D3_GASAC/61-191   AC G3P5D3.1
#=GS F4QE00_DICFS/190-323  AC F4QE00.1
#=GS F6J1X5_DROME/194-244  AC F6J1X5.1
#=GS E9I4E3_DAPPU/1-92     AC E9I4E3.1
#=GS G3SX70_LOXAF/61-191   AC G3SX70.1
#=GS B4YWY5_DROME/187-217  AC B4YWY5.1
#=GS G5BYG0_HETGA/61-191   AC G5BYG0.1
#=GS H2TN35_TAKRU/61-191   AC H2TN35.1
#=GS H0VRS9_CAVPO/61-191   AC H0VRS9.1
#=GS E2AAE7_CAMFO/145-273  AC E2AAE7.1
#=GS B3NT23_DROER/196-327  AC B3NT23.1
#=GS G3V1P3_HUMAN/42-172   AC G3V1P3.1
#=GS H2TN36_TAKRU/18-143   AC H2TN36.1
#=GS F6JD67_DROSN/196-236  AC F6JD67.1
#=GS O01902_CAEEL/64-216   AC O01902.2
#=GS F6YM17_ORNAN/61-191   AC F6YM17.1
#=GS G0NAV5_CAEBE/66-218   AC G0NAV5.1
#=GS F6YFT8_MACMU/61-191   AC F6YFT8.1
#=GS G3HB29_CRIGR/31-161   AC G3HB29.1
#=GS E9Q2W8_MOUSE/62-192   AC E9Q2W8.1
#=GS L12R1_XENTR/61-191    AC A8E5U3.1
#=GS F6RB72_XENTR/61-153   AC F6RB72.1
#=GS G6DBX6_DANPL/125-260  AC G6DBX6.1
#=GS H0XJX8_OTOGA/61-191   AC H0XJX8.1
#=GS B4IK77_DROSE/196-327  AC B4IK77.1
#=GS L12R1_HUMAN/61-191    AC Q969J3.1
#=GS A9YGP0_DROME/194-244  AC A9YGP0.1
#=GS Q9VYT1_DROME/196-327  AC Q9VYT1.1
#=GS H2L611_ORYLA/62-192   AC H2L611.1
#=GS F6TND5_HORSE/61-191   AC F6TND5.1
#=GS D9MT53_DROMI/107-162  AC D9MT53.1
#=GS D9MT70_9MUSC/107-162  AC D9MT70.1
#=GS F6JDA1_DROTE/196-236  AC F6JDA1.1
#=GS E1FL87_LOALO/61-192   AC E1FL87.1
#=GS G5E1G7_9PIPI/13-68    AC G5E1G7.1
#=GS G1PU12_MYOLU/61-191   AC G1PU12.1
#=GS Q16I41_AEDAE/1-131    AC Q16I41.1
#=GS B4NDQ2_DROWI/211-342  AC B4NDQ2.1
#=GS F6JD91_DROTE/196-236  AC F6JD91.1
#=GS F6J1X6_DROME/194-244  AC F6J1X6.1
#=GS A9YGN7_DROSI/194-244  AC A9YGN7.1
#=GS F6JD71_DROSN/196-236  AC F6JD71.1
#=GS G1QTL9_NOMLE/61-191   AC G1QTL9.1
E9BY13_CAPO3/94-225              ..............................TFLPILRSAIDNNwylSS.R..D.FE....sVDVQ....LESSAIMTLASRTQQ....HFAHLADRVS...SEQNAIDESIRRTEVVTARA.....SAALAQRQKNATRMAG.AAAE...IQSMIKTLTSLQA...............ATQRLSESCRQLNALLPES-----------vqeplngp.............
H3FK84_PRIPA/46-173              ..............................RFLPILRSAIGRR...D-.-..-.IC.....EHRD....ISPRPFLQLSLRLSN....HFALCAKAVN...MKQSQLSGAMKTMDNRLVEM.....TAEITERKRRLDRLCE.ALER...VELMNNELMKMND...............SFGALTASLEDLTLLLPSNMILPPLRITP-p....................
E2BHD6_HARSA/148-276             ..............................MFLPIMRGTLNLP...PGvR..D.PE.....VLER....LDPVGLFNLCARYQH....HLNTNAQTVA...AEQAAL---CASMETDLAKM.....LNQAVERQKRFARFAE.QLNK...VHELSRQLTRCHS...............QLNQTLESLETLNNLLPVEERLEPFVWTT-g....................
D9MT74_9MUSC/107-162             ..............................QFLPVLRESISSA...TYtR..D.AE.....ILER....LHSQHLINICTRMQT....HLNLCACYVS...SEQNHLV-------------.....----------------.----...-------------...............------------------------------.....................
Q16ZQ2_AEDAE/218-278             ..............................MFLPVMRGTLSLP...AN.R..D.PE.....VLER....LHPNHMINMCSRLQS....HFNTCATQVA...SEQQQITNKIKEV-------.....----------------.----...-------------...............------------------------------.....................
G7PJV8_MACFA/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GVDQTVPLLDRLNSLLPESERLEPFSMKPD.....................
B5LFR2_DROSI/196-246             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
F6JGP5_DROSI/194-244             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
F7IJ41_CALJA/18-143              ............................ss-------GLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLLDRLNSMLPEGERLEPFSMKPD.....................
G3MRS5_9ACAR/80-210              ..............................QFWPILKGSLHSP...II.C..D.TD.....VGER....LDHRAVNRLTSRYQE....HLRQCAEVVS...TEQNALAARIREVDYAVSTL.....NTMMTERQKKFGKYVE.QLLK...VHELSNLLQTTES...............LLAKTVEQLDQLNRQLPPDEQLEPFVMVT-g....................
Q29H95_DROPS/187-318             ..............................QFLPVLRESISSA...TYtR..D.AE.....ILER....LHSQHLINICTRMQT....HLNLCACYVS...SEQNHLVERTKVVSNSITTL.....FASFVDMQKTYASYAE.QFAK...IRSVSHQLSRCNS...............LLHENIASLEAINNFLDDEDRLEPFVWRTD.....................
F1PDM0_CANFA/1-124               ..............................-------GLLSGQ...TS.P..T.NT.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSMLPEGERLEPFSMKPD.....................
H9HD41_ATTCE/151-279             ..............................MFLPIMRGTLNLP...PGvR..D.PE.....ILER....LDPVGLFNLCARYQH....HLNTNAQVIA...AEQVTL---CTNMETEFGKV.....LHLAVDRQKKFAKFTE.QINK...VHELSRQLTRCHS...............LLNQTLESLETLNNLLPIEERLEPFVWTT-g....................
G3MPH3_9ACAR/113-243             ..............................QFWPILKGSLHSP...II.C..D.TD.....VGER....LDHRAVNRLTSRYQE....HLRQCAEVVS...TEQNALAARIREVDYAVSTL.....NTMMTERQKKFGKYVE.QLLK...VHELSKLLQTTES...............LLAKTVEQLDQLNRQLPPDEQLEPFVMVT-g....................
H2VS43_CAEJA/125-293             ..............................RFLPVIPSVIGKK...DP.H..I.SGqtvsyTHQK....ISSRPFFRLATRLQE....HFSLNAKMVA...AQQSKIPVSCKSVETRLVKL.....CEETRARKCQHDAFIV.ALGG...LNQLHEDICRIQVflklnlvnifkllklLLEEIVPVVETLNEILVPEDRLPLLNL---gsvldrspvpssdsslqstpr
F1LER0_ASCSU/66-211              ..............................KFYPVLRSALNQA...SL.R..D.PP....dITMK....IGPRPILRFACRLQD....HLAQCALAVA...TEQDALTAVIKNVEYALSSI.....TSKVTERKKRFDRLAG.ELQR...ARELQTQIINVRF...............LLQDLVPCVETLNEILPVEERLPSLNL---grvlertpvmssgessp....
G1LW93_AILME/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NT.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSMLPEGERLEPFSMKPE.....................
H3J1M7_STRPU/112-242             ..............................TFMPILKGTHSVP...QV.E..D.PN.....QMEK....MDHRQLLLLCLRYQH....HLRQCSEAVT...FDQNALTGRIKEVDAIIHSI.....MQSMAERQKRFAKHAE.QIQK...INEMSGTLKRVQM...............SVDQLIPLMDRLNSVLPDAERLEPFTMRP-t....................
F6JGP6_DROSI/194-244             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
B4L2E2_DROMO/213-344             ..............................QFLPVLRESISSA...TYtR..D.PE.....ILER....LNSQHLLNICSRMQT....HLNLCASHVA...SEQNHLVERTKVVSNSITTL.....FASFVDMQKTYASYAE.QFAK...IRGVSQQLSRCNS...............LLHENIASLEAINNFLDDDDRLEPFVWRTD.....................
H9K1A3_APIME/141-269             ..............................MFLPIMRGTLNLP...PGvR..D.PE.....VLER....LNPIGLFNLCARYQH....HLNTNAQMIA...TEQASL---CINIEPEVTKI.....LNLATERQKKFAKFAE.QLNK...IHELSKQLTKCHS...............LLNQTLESLETLNNLLPIEDRLEPFVWTT-g....................
F6PG67_MONDO/60-190              ..............................TFQPLLKGLLSGQ...TS.P..T.NT.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVS...FDQNALVKRIKEMDLTVETL.....FGFMQERQKRYSKYAE.QIQK...VNEISSILRRIQM...............GIDQTVPLMERLNNLLPESERLEPFSMKPD.....................
D9MT67_DROMI/107-162             ..............................QFLPVLRESISSA...TYtR..D.AE.....ILER....LHSQHLINICTRMQT....HLNLCACYVS...SEQNHLV-------------.....----------------.----...-------------...............------------------------------.....................
D9MT57_DROMI/107-162             ..............................QFLPVLRESISSA...TYtR..D.AE.....ILER....LHSQHLINICTRMQT....HLNLCACYVS...SEQNHLV-------------.....----------------.----...-------------...............------------------------------.....................
F6J1X7_DROME/194-244             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLINICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
F7IJ39_CALJA/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLLDRLNSMLPEGERLEPFSMKPD.....................
B0X6W7_CULQU/191-321             ..............................MFLPVMRGTLSLP...AN.R..D.PE.....VLER....LQPAHMVNMCSRLQS....HFNTCATQVA...QEQQQITNKIKETDQEISSA.....LAQLVQKQKLYTSYAE.TFSK...VRLISQQLTRCND...............ILNQNIESMEYLNNLLELEDRLEPFVWKTE.....................
A8WU98_CAEBR/68-220              ..............................RFLPVIPAVIGKR...DP.S..S.NQsa.syTHQK....ISSRPFFRLASRLQE....HFALNAKAVA...ADQSKIPAICKSVEAKMIKL.....IEETQSHKAQHDAFKT.ALNG...LNQLHDDISKIQC...............LLEDIVPMVETLNEILVPEDRLPPLNL---gsvldrspvpssdssfqstpr
B4YWY4_DROME/187-217             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLI--------....----------...--------------------.....----------------.----...-------------...............------------------------------.....................
H2R1T3_PANTR/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLLDRLNSMLPEGERLEPFTMKPD.....................
A9YGP1_DROME/194-244             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLINICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
G1NS04_MELGA/1-74                .............................f-------------...--.-..-.--.....----....---------------....----------...----------KQMDLSVETL.....YSLMQERQKKYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSMLPESEQLEPFSMKPD.....................
G3WJ41_SARHA/52-182              ..............................TFQPLLKGLLSGQ...TS.P..T.NT.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVS...FDQNALVKRIKEMDITVETL.....FGYMQERQKKYSKYAE.QIQK...VNEISSILRRIQM...............GIDQTVPLMERLNSLLPENERLEPFSMKPD.....................
B3RIX6_TRIAD/60-187              ..............................KFSPLMRGSLNLP...VM.R..D.SG.....FLSK....MESKHVISYVNRYEE....HLRLCSQMIT...NDQVMLASRMKEIDYLMDLV.....HNKVAERQQKLNHFAV.CART...IQTIESDIQRIQK...............NLEDSTALAEQFNDLLPEGHKLEPLS----r....................
F1NG32_CHICK/1-128               ..............................---PCFAGLLSGQ...TS.P..T.NT.....KLEK....LDPHQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....YSFMQERQKKYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSMLPESEQLEPFSMKPD.....................
B4R391_DROSI/3-74                ..........................iisf-------------...--.-..-.--.....----....---------------....----------...---------------CITTL.....FAGFVDMQKTYASYAE.QFAK...IRSISHQLSRCNS...............LLHENIASLEAINNFLDDEDRLEPFVWRTD.....................
G1KCT8_ANOCA/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NI.....KLEK....LDSQQVLQLCLRYQE....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....YSLMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDLTIPLMERLNSMLPESEQLEPFSMKPD.....................
F6YM09_ORNAN/20-144              .............................g-------GLLSSQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FGFMQERQKRYAKYAE.QIQK...VNEMSATLRRIQM...............GIDQTGPLVDRLNCLLPQSERLEPFSTHPD.....................
F6JD79_DROSN/196-236             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICARMQT....HL--------...--------------------.....----------------.----...-------------...............------------------------------.....................
F6JD45_DROYA/196-236             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICARMQT....HL--------...--------------------.....----------------.----...-------------...............------------------------------.....................
D9MT69_9MUSC/107-162             ..............................QFLPVLRESISSA...TYtR..D.AE.....ILER....LHSQHLINICTRMQT....HLNLCACYVS...SEQNHLV-------------.....----------------.----...-------------...............------------------------------.....................
F7IJ40_CALJA/8-140               ......................vfnnllnf------EGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLLDRLNSMLPEGERLEPFSMKPD.....................
D9MT52_DROAI/107-162             ..............................QFLPVLRESISSA...TYtR..D.AE.....ILER....LHSQHLINICTRMQT....HLNLCACYVS...SEQNHLV-------------.....----------------.----...-------------...............------------------------------.....................
L12R1_BOVIN/61-191               ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLLERLNSLLPEAERLEPFSVKPD.....................
G3RZM1_GORGO/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLLDRLNSMLPEGERLEPFSMKPD.....................
F6YFS9_MACMU/18-143              ............................ss-------GLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GVDQTVPLLDRLNSLLPESERLEPFSMKPD.....................
G3S234_GORGO/8-139               .......................vfselvk------EGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLLDRLNSMLPEGERLEPFSMKPD.....................
B4JL73_DROGR/199-330             ..............................QFLPVLRESISSA...TYtR..D.AE.....ILER....LHSQHLLNICGRMQT....HLNLCASHVA...SEQNHLVERTKVVSNSITTL.....FASFVDMQKTYASYAE.QFAK...IRGVSQQLSRCNS...............LLHENIASLEAINNFLDDEDRLEPFVWRTD.....................
D2A5H3_TRICA/132-262             ..............................MFLPIMRATLNLP...AA.R..D.PE.....VLER....LDPAPLHKLCVKYQT....HLTACANLIA...TEQNQLTQKVRETDGEIARI.....INGLGERQKRFAKYAE.KLSK...VQELSHQLNRCHM...............LLNQTLESMETLNNHLDIEDRLEPFVWTT-g....................
G1SZM8_RABIT/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NT.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSLLPEGERLEPFSVKP-g....................
L12R1_XENLA/61-191               ..............................TFQPLLKGLLSGQ...TS.P..T.NV.....RLER....LDSPQVLQLCVRYQE....HLHQCAEAVS...FDQNALVKRIKEMDSSVDGL.....YSLMQERQKRFAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMEKLNIMLPEGERLEPFCMSPD.....................
D4XWZ8_9MOLU/51-172              ...........dtnsktnsiipvalyakpl-------------...--.-..-.--.....KFEK....IKSEYFLT--FKGIE....RLKLTGDSLN...FDENNFTKSEKQTAEEFENV.....YKNFVRADKLHKSFDS.IIEE...IKETQETISSIPN...............LLYETYSNLEKMNESL--------------lklnpyt..............
C3Y7G4_BRAFL/27-157              ..............................TFLPIMRGSLNVP...NM.R..D.PD.....VLDK....LDSKEVLKMCLRYQE....HMKQCAEAVA...FDQNSLTNRTKEMDFAITAL.....TNMMTEHQKKYAKYAE.QIMK...INEMSQTLKRCQM...............AVDQLLPLMDRLNSVLPEEQRLEPFTMRP-g....................
C1BUN3_9MAXI/100-225             .............................s-FLPIMRG-----...SS.R..D.PD.....ILER....LDVRGFNALVQRYSN....HLRYTSKIIK...DTQSEINKSIKETEALSASV.....LDQMNKNSSSYSKYAE.KLAK...ASVMSRALNKCHS...............SLNENIERMEVLNNMLPMEERLEPFVWTT-g....................
I1G2L4_AMPQE/79-210              ..............................KFWPILKSTLDYE...YP.L..E.-S.....FQKG....LSSPDLLSLSQDYKK....HLNLIAQVIA...NKQRALASRMKDIEMFSAGI.....AQQLEKRHERIEKALP.HLER...VNELSQVLDNIGS...............LLDDVVPLMNRINYSLPESSRLEQLTV---hksth................
A8PQW4_BRUMA/61-192              ..............................KFYPILKSSLNQP...DL.R..DsPE.....ATPK....VNARPVLKFACRLQE....HFSRCANTVV...VEQELLGNSMKHVDRNITLL.....LVQFAEQKKSMDRFQN.YLEK...MNDLQAHISNLRF...............LFQDLMPVINTLNEILPEHKRLPLL-----didcl................
H2ZJF3_CIOSA/56-186              ..............................KFLPLLPNSLAVP...ES.RpiT.AE.....LSGQ....LDVQSCIRACGRLQD....HLNQCASAVS...FDQKALETKIKEVDKVGVSV.....MQHMTERQRAFAKHAE.HSRK...VDDISTTLNRVRM...............NLEQTLSLVDELNMSLPEELRLEKLNL---i....................
E3M4S4_CAERE/66-216              ..............................RFLPVIPAVIGKR...DS.Q..S.NQga.syTHQK....ISSRPFFRLATRLQE....HFALNAKAVA...ADQAKIPANCKSVEAKMIRL.....IEETRAHKSQHDGFVA.ALTG...LNKLHDDICRIQI...............LLENIVPMVETLNEILIPEDRLPPLNL---gsvldrspvcssdsslqst..
A9YGP9_DROME/194-244             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLINICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
A7UV35_ANOGA/193-323             ..............................MFLPVMRGTLTLP...AN.R..D.PE.....VLER....LQPTHLINMCSRLQS....HFNTCAVHVS...SEQQQITNRIKEVDQEVSSA.....LAQLVQKQKLYTSYAE.TFSK...VRQISQQLTRCND...............ILNQNIESMEYLNNLLSVDDRLEPFVWKTE.....................
G0PJX7_CAEBE/66-169              ..............................RFLPVIPAVIGKR...DP.Q..P.SQaa.syTHQK....ISSRPFSRLALRLQE....HFAVNAKAVA...ADQAKIPATCKSVEAKMIRL.....VEETKTHKAEHDAFVV.ALSG...LNKLHEEISRIQ-...............------------------------------.....................
B3N1E3_DROAN/199-330             ..............................QFLPVLRESITSA...TYtR..D.AE.....ILER....LHSQHLVNICTRMQT....HLNLCANYVS...SEQNHLVERTKVVSNSITTL.....FASFVDMQKTYASYAE.QFVK...IRNVSHQLSRCNS...............LLHENIASLEAINNFLDDEDRLEPFVWRTD.....................
B7PUZ3_IXOSC/77-207              ..............................QFLPILRGSLHSP...II.C..D.AD.....VADK....LDHRAVNRLASRYQD....HLRQCAEVVS...TEQNALASRIREMDYAVSTL.....SNMLTERQKKFAKYVE.QLSR...VHELSGMLQTSQT...............LLTKTIEQLDTLNKLLPPDEQLEPFIMVT-g....................
A3Z3Y6_9SYNE/7-111               .....................rkpsslich-------------...--.-..-.--.....---V....LSSAQSFRLAAAMTQsvsfRITRTAEDVA...QTLNALSQRLVKLEQRLESL.....ELQLRQQQQAGTMAAE.ELER...LDGVDLILQECQD...............LLRES-------------------------eaitepss.............
H2L613_ORYLA/18-143              ............................ss-------GVLSGQ...TS.P..S.SL.....SLER....LDAAQVLQLCIRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSIMQERQKRYAKYAE.QIQK...VNEMSMILRRIQM...............GIDQTVPLMERLNNMLPESERLEPFSMRA-d....................
B5LFR0_DROSI/196-246             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
B4YWZ4_DROME/187-231             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLINICTRMQT....HLNL------...--------------------.....----------------.----...-------------...............------------------------------ph...................
H3BGN5_LATCH/61-191              .............................a-FQPLLKGLLSGQ...TS.P..S.NS.....RLEK....LDPHQVMQLSRRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVEAL.....YSVMQDRQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMEKLNSLLPESERLEPFGMKPD.....................
E4YFP3_OIKDI/154-281             ........aqlawlsrekrvdavitgkvld-------------...--.-..-.--.....-FQT....FASYNLTAICSEISV....FLDTSAAEIA...TKQTGIQKQIGQFDQSMAKI.....DENIE--KQNMSKFCS.ELNK...LETMKNRTEGLSK...............NLHDLASSINSINQKLPEEKRLPPLK----f....................
F6JD97_DROTE/196-236             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICARMQT....HL--------...--------------------.....----------------.----...-------------...............------------------------------.....................
H2NGM6_PONAB/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLLDRLNSMLPEGERLEPFSMKPD.....................
B1H257_RAT/61-191                ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....RLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FCFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSMLPEAERLEPFSMRPE.....................
A9YGP3_DROME/194-244             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLINICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
B5LFP8_DROSI/196-246             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
A9YGN8_DROME/194-244             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLINICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
L12R1_DANRE/61-181               ..............................TFQPLLKGVLSGQ...TS.P..S.TV.....CLEK....LDSAQVLQLCVRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVEAL.....FSIMQERQKRYAKYAE.QIQK...VNEMSMILRRIQM...............GIDQTVPLMERLNNMLPE------------sl...................
D3PHH9_9MAXI/100-225             .............................s-FLPIMRG-----...SS.R..D.PD.....ILER....LDVRGFNALVQRYSN....HLRYTSKIIK...DTQSEINKSIKETEALSASV.....LDQMNKNSSSYSKYAE.KLAK...ASDMSRALNKCHS...............SLNENIERMEVLNNMLPMEERLEPFVWTT-g....................
F6JD90_DROTE/196-236             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICARMQT....HL--------...--------------------.....----------------.----...-------------...............------------------------------.....................
F6JD75_DROSN/196-236             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICARMQT....HL--------...--------------------.....----------------.----...-------------...............------------------------------.....................
F6JGP7_DROSI/194-244             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
B4YWY1_DROME/187-217             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLI--------....----------...--------------------.....----------------.----...-------------...............------------------------------.....................
L12R1_CHICK/50-180               ..............................TFQPLLKGLLSGQ...TS.P..T.NT.....KLEK....LDPHQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....YSFMQERQKKYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSMLPESEQLEPFSMKPD.....................
A7S969_NEMVE/67-200              .........................yiplv--RPILNASVQVT...PA.R..E.LE.....RLEK....FDLRPALKLCSRYED....HLRQCSEAVA...FDQDMLASRIKEVDVNSTAV.....LSAVNDRHRKLVHVIA.HLKK...VEEMSFTLRRIDA...............SMKKIVPLIDRLNNILPEEERLDPFSFEP-g....................
E5SUA4_TRISP/41-126              ..................eqlesefltklk-------------...--.-..-.--.....----....---------------....----------...------------VDSMLSKL.....RPYPVIKFKQFARLNG.DLSQ...IENLYMQVASISS...............LLKEVVSLADRVNALLPERNRLPPLS----tlirtee..............
E0W036_PEDHC/143-295             mflpimrgtlnlpgkyknfiqviccihcqk--------VIFFK...RM.R..D.PE.....ILER....LDPQDLLGLCKKLQN....YMSLCVNCAT...KNQNQIINRIREVDFELCHL.....VVSLGERQKKLVKETE.KISK...IKEISVMLNKCHS...............QLNHSLELIEILNNALPSKYRLEPFVWTT-g....................
F6JGQ5_DROSI/194-244             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
D5G9I7_TUBMM/160-269             ..........................alsa-------------...--.-..-.--.....----....-----VSRLCSEYQS....SLQTEVDGLV...EAQSHIDARMKEADKLTAQA.....LKTTKIRTERLDSESS.GLKGgsaVDALAEAAEATHT...............TLTSIVTTLLAIDEMLPAQERLSPLT----sahk.................
C3Y7G6_BRAFL/36-166              ..............................TFLPIMRGSLNVP...NM.R..D.PD.....VLDK....LDSKEVLKMCLRYQE....HMKQCAEAVA...FDQNSLTNRTKEMDFAIAAL.....TNMMTDHQKKYAKYAE.QIMK...INEMSQTLKRCQM...............AVDQLLPLMDRLNSVLPEEQRLEPFSMRP-g....................
Q4S181_TETNG/61-191              ..............................TFQPLLKGVLSGQ...TS.P..S.SV.....CLER....LDAAQVLQLCVRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSIMQERQKRYAKYAE.QIQK...VNEMSMILRRIQM...............GIDQTVPLMERLNNMLPESERLEPFSMRPD.....................
G3P5C9_GASAC/40-170              ..............................TFQPLLKGVLSGQ...TS.P..S.SV.....CLER....LDAAQVLQLCIRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSIMQERQKRYAKYAE.QIQK...VNEMSMILRRIQM...............GIDQTVPLMERLNNMLPESERLEPFSMRPD.....................
F1NRC3_CHICK/20-150              ...........................vcs---PCFAGLLSGQ...TS.P..T.NT.....KLEK....LDPHQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....YSFMQERQKKYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSMLPESEQLEPFSMKPD.....................
F6JD44_DROYA/196-236             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICARMQT....HL--------...--------------------.....----------------.----...-------------...............------------------------------.....................
B4GY33_DROPE/187-318             ..............................QFLPVLRESISSA...TYtR..D.AE.....ILER....LHSQHLINICTRMQT....HLNLCACYVS...SEQNHLVERTKVVSNSITTL.....FASFVDMQKTYASYAE.QFAK...IRSVSHQLSRCNS...............LLHENIASLEAINNFLDDEDRLEPFVWRTD.....................
B4YWZ3_DROME/187-217             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLI--------....----------...--------------------.....----------------.----...-------------...............------------------------------.....................
F6JD52_DROYA/196-236             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICARMQT....HL--------...--------------------.....----------------.----...-------------...............------------------------------.....................
L12R1_MOUSE/61-191               ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FCFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSMLPEAERLEPFSMKPE.....................
B4Q1I2_DROYA/196-327             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICARMQT....HLNLCASYVA...SEQNHLVERTKVVSNSITTL.....FAGFVDMQKTYASYAE.QFAK...IRSISHQLSRCNS...............LLHENIASLEAINNFLDDDDRLEPFVWRTD.....................
B5LFQ9_DROSI/196-246             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
G9K8F1_MUSPF/41-176              ..............................TFQPLLKGLLSGQ...TS.P..T.NT.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETLxvetrFSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSLLPESERLEPFSMKPE.....................
F4WS06_ACREC/144-272             ..............................MFLPIMRGTLNLP...PGvR..D.PE.....VLER....LDPVGLFNLCARYQH....HLNTNAQIIA...AEQVTL---CTSMETEFGKV.....LNLAVDRQKKFVKFTE.QINK...VHELSRQLTRCHS...............LLNQTLESLETLNNLLPIEERLEPFVWTT-g....................
B4M1I1_DROVI/204-335             ..............................QFLPVLRESISSA...TYtR..D.TE.....ILER....LHSQHLLNICGRMQT....HLNLCASHVA...SEQNHLVERTKVVSNSITTL.....FASFVDMQKTYASYAE.HFAK...IRSVSQQLSRCNS...............LLHENIASLETINNFLDDEDRLEPFVWRTD.....................
H9JNP2_BOMMO/137-197             ..............lqglvtvsrrafkfes-------------...--.-..-.--.....-LLG....LDYKPWVRLTTRLQA....HLAACAHPLA...AEEVSLASKIKETI------.....----------------.----...-------------...............------------------------------qdi..................
Q86IZ8_DICDI/148-265             .................ikylkkkhhisip-------------...--.-..-.--.....---E....MDHRGYLNLCIDIQN....YLKNSTGYIH...EKQNEILQKIRDVETKQAKK.....ITNIMQIKTSDATHAQfGIKE..vMDKVKGNLDKSKE...............IIHKISFLIEKIESTLPEDE----------inel.................
H3D892_TETNG/61-191              ..............................TFQPLLKGVLSGQ...TS.P..S.SV.....CLER....LDAAQVLQLCVRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSIMQERQKRYAKYAE.QIQK...VNEMSMILRRIQM...............GIDQTVPLMERLNNMLPESERLEPFSMRPD.....................
F6JMB5_DROSI/163-212             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICTRMQT....HLNLCASYVA...S-------------------.....----------------.----...-------------...............------------------------------.....................
F6JMA3_DROSI/163-212             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICTRMQT....HLNLCASYVA...S-------------------.....----------------.----...-------------...............------------------------------.....................
D2H874_AILME/43-173              ..............................TFQPLLKGLLSGQ...TS.P..T.NT.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSMLPEGERLEPFSMKPE.....................
H0ZR43_TAEGU/61-194              ..............................TFQPLLKGLLSGQ...TS.P..A.NT.....KLEK....LDPQQVLQLCLRYQD....HLHQCAEAVAgcgFDQNALVKRIKEMDLSVETL.....YSLMQERQKKYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSLLPEGEQLEPFSMKPD.....................
B4YWY2_DROME/187-217             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLI--------....----------...--------------------.....----------------.----...-------------...............------------------------------.....................
G3P5D3_GASAC/61-191              ..............................TFQPLLKGVLSGQ...TS.P..S.SV.....CLER....LDAAQVLQLCIRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSIMQERQKRYAKYAE.QIQK...VNEMSMILRRIQM...............GIDQTVPLMERLNNMLPESERLEPFSMRPD.....................
F4QE00_DICFS/190-323             ...........ipiikqdslldrianiadk-------------...--.H..H.RP.....TLPM....INVDPVERLLSSYGS....YLKSTSHELG...DKQESLNKKLKEMELLCSKG.....HQLMLKHVTLIKQTTN.ILPD...INKLNQNIKETQM...............IMNNVLDTIERLTSILPNHD----------eeliefsqs............
F6J1X5_DROME/194-244             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LKSQHLINICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
E9I4E3_DAPPU/1-92                .............................m-------------...--.-..-.--.....----....---------------....--KQNAETVV...TEQNQLAQSSKDIEAQFAAI.....MTALTERQKMYAKYAE.KLAR...IHEVSHSLTRCQL...............ALATALDSIETLNRQLPTSDRLEEFIWST-g....................
G3SX70_LOXAF/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NT.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLFVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSMLPESERLEPFSMKPD.....................
B4YWY5_DROME/187-217             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLI--------....----------...--------------------.....----------------.----...-------------...............------------------------------.....................
G5BYG0_HETGA/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NT.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALIKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSLLPEGERLEPFSMKPE.....................
H2TN35_TAKRU/61-191              ..............................TFQPLLKGVLSGQ...TS.P..S.SV.....YLER....LDAAQVLQLCIRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSIMQERQKRYAKYAE.QIQK...VNEMSMILRRIQM...............GIDQTVPLMERLNNMLPESERLEPFSMRPD.....................
H0VRS9_CAVPO/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSLLPEGERLEPFSMKPE.....................
E2AAE7_CAMFO/145-273             ..............................MFLPIMRGTLNLP...PGvR..D.PE.....VLER....LDPVGLFNLCARYQH....HLNTNAQTIA...MEQVSL---CTNVEAEFAKA.....LNFAVDRQKKFARFAE.QLNK...VHELSRQLTRCHS...............LLNQTLESLETLNNLLPIEERLEPFVWTT-g....................
B3NT23_DROER/196-327             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICARMQT....HLNLCASYVA...SEQNHLVERTKVVSNSITTL.....FAGFVDMQKTYASYAE.QFAK...IRSISHQLSRCNS...............LLHENIASLEAINNFLDDDDRLEPFVWRTD.....................
G3V1P3_HUMAN/42-172              ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLLDRLNSMLPEGERLEPFSMKPD.....................
H2TN36_TAKRU/18-143              ............................st-------GVLSGQ...TS.P..S.SV.....YLER....LDAAQVLQLCIRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSIMQERQKRYAKYAE.QIQK...VNEMSMILRRIQM...............GIDQTVPLMERLNNMLPESERLEPFSMRPD.....................
F6JD67_DROSN/196-236             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICARMQT....HL--------...--------------------.....----------------.----...-------------...............------------------------------.....................
O01902_CAEEL/64-216              ..............................RFLPVIPAVIGKR...DP.Q..T.NQga.syTHQK....ISSRPFFRLATRLQE....HFAVNAKAVA...ADQAKIPATCKSVEAKMIRL.....IEETRAHKEQHDGFMA.ALSG...LNQLHDDICSIQI...............ILEDIVPMVETLNEILTPDERLPPLNL---gsvldrspvpssdsslqstpr
F6YM17_ORNAN/61-191              ..............................TFQPLLKGLLSSQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FGFMQERQKRYAKYAE.QIQK...VNEMSATLRRIQM...............GIDQTGPLVDRLNCLLPQSERLEPFSTHPD.....................
G0NAV5_CAEBE/66-218              ..............................RFLPVIPAVIGKR...DP.Q..S.SQaa.syTHQK....ISSRPFSRLALRLQE....HFAVNAKAVA...ADQAKIPATCKSVEAKMIRL.....VEETKTHKAEHDAFVV.ALSG...LNKLHEEISRIQI...............ILEDIVPMVETLNEILTPDERLPQLNL---gsvldrspvpssesslqstpr
F6YFT8_MACMU/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GVDQTVPLLDRLNSLLPESERLEPFSMKPD.....................
G3HB29_CRIGR/31-161              ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FCFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSMLPEAERLEPFSMRPE.....................
E9Q2W8_MOUSE/62-192              ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FCFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSMLPEAERLEPFSMKPE.....................
L12R1_XENTR/61-191               ..............................TFQPLLKGLLSGQ...TS.P..T.NV.....RLER....LDSPQVLQLCVRYQE....HLHQCAEAVS...FDQNALVKRIKEMDSSVDGL.....YSLMQERQKRFAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMEKLNIMLPEGERLEPFCMSPD.....................
F6RB72_XENTR/61-153              ..............................TFQPLLKGLLSGQ...TS.P..T.NV.....RLER....LDSPQVLQLCVRYQE....HLHQCAEAVS...FDQNALVKRIKEMDSSVDGL.....YSLMQERQKRFAKYAE.QIQK...VNEMS--------...............------------------------------.....................
G6DBX6_DANPL/125-260             ..............................TFLPIMRGTLGLP...GA.K..D.PE.....VLEGlyigLDSRPWIRMSSRVQA....HLAACAQPLA...ADEINLASKIKEADTEITRL.....YTAAVEKQRSNARHAE.RLSR...VRELHHQLSRCNS...............LLNQTLQDIEELNQLLPEDKRLQPFVWN--enk..................
H0XJX8_OTOGA/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QMQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSTLPESERLEPFSMKPD.....................
B4IK77_DROSE/196-327             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICTRMQT....HLNLCASYVA...SEQNHLVERTKVVSNSITTL.....FAGFVDMQKTYASYAE.QFAK...IRSISHQLSRCNS...............LLHENIASLEAINNFLDDEDRLEPFVWRTD.....................
L12R1_HUMAN/61-191               ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLLDRLNSMLPEGERLEPFSMKPD.....................
A9YGP0_DROME/194-244             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLINICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
Q9VYT1_DROME/196-327             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLINICTRMQT....HLNLCASYVA...SEQNHLVERTKVVSNSITTL.....FAGFVDMQKTYASYAE.QFAK...IRSISHQLSRCNS...............LLHENIASLEAINNFLDDEDRLEPFVWRTD.....................
H2L611_ORYLA/62-192              ..............................TFQPLLKGVLSGQ...TS.P..S.SL.....SLER....LDAAQVLQLCIRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSIMQERQKRYAKYAE.QIQK...VNEMSMILRRIQM...............GIDQTVPLMERLNNMLPESERLEPFSMRA-d....................
F6TND5_HORSE/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSLLPEGERLEPFSMKPD.....................
D9MT53_DROMI/107-162             ..............................QFLPVLRESISSA...TYtR..D.AE.....ILER....LHSQHLINICTRMQT....HLNLCACYVS...SEQNHLV-------------.....----------------.----...-------------...............------------------------------.....................
D9MT70_9MUSC/107-162             ..............................QFLPVLRESISSA...TYtR..D.AE.....ILER....LHSQHLINICTRMQT....HLNLCACYVS...SEQNHLV-------------.....----------------.----...-------------...............------------------------------.....................
F6JDA1_DROTE/196-236             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICARMQT....HL--------...--------------------.....----------------.----...-------------...............------------------------------.....................
E1FL87_LOALO/61-192              ..............................KFYPILKSSLNQP...SL.R..DsPE.....TIFK....VNARPVLKFAYRLQE....HLSKCANVVA...VEQESLGNSIKNIDRDIAVL.....LVQFGDRKRLMDRFQN.YLEQ...MNGLRAHISNLRF...............LFQDLIPVTKTLNEILPEQKRLPLL-----didcl................
G5E1G7_9PIPI/13-68               ..............................TFQPLLKGLLSGQ...TS.P..T.NV.....RLER....LDSPQVLQLCVRYQD....HLHQCAEAVS...FDQNALVK------------.....----------------.----...-------------...............------------------------------.....................
G1PU12_MYOLU/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NT.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLMERLNSMLPEGERLEPFSMKPD.....................
Q16I41_AEDAE/1-131               ..............................MFLPVMRGTLSLP...AN.R..D.PE.....VLER....LHPNHMINMCSRLQS....HFNTCATQVA...SEQQQITNKIKEVDQEISSA.....LAQLVQKQKLYTSYAE.TFSK...VRVISQQLTRCND...............ILNQNIESMEYLNNLLDVDDRLEPFVWKTE.....................
B4NDQ2_DROWI/211-342             ..............................QFLPVLRESITSA...TYtR..D.SE.....ILER....LHSQHLTNICTRMQT....HLNLCATHVA...SEQNHLVERTKVVSNSITTL.....FASFVDMQKTYASYAE.QFAK...IRGISQQLSRCNS...............LLHENIASLEAINNYLDDEDRLEPFVWRTD.....................
F6JD91_DROTE/196-236             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICARMQT....HL--------...--------------------.....----------------.----...-------------...............------------------------------.....................
F6J1X6_DROME/194-244             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLINICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
A9YGN7_DROSI/194-244             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICTRMQT....HLNLCASYVA...SE------------------.....----------------.----...-------------...............------------------------------.....................
F6JD71_DROSN/196-236             ..............................QFLPVLRESITSA...TNtR..D.AE.....ILER....LNSQHLVNICARMQT....HL--------...--------------------.....----------------.----...-------------...............------------------------------.....................
G1QTL9_NOMLE/61-191              ..............................TFQPLLKGLLSGQ...TS.P..T.NA.....KLEK....LDSQQVLQLCLRYQD....HLHQCAEAVA...FDQNALVKRIKEMDLSVETL.....FSFMQERQKRYAKYAE.QIQK...VNEMSAILRRIQM...............GIDQTVPLLDRLNSMLPESERLEPFSMKPD.....................
#=GC seq_cons                    ..............................pF.PlL+tslout...Ts....s.sp.....hLE+....LsSppllplChRhQs....HLp.CAphVA....-QstLstphKph-.thtpl.....ht.h.ptpcpaspasp.pht+...lpphpt.lpchp................hlpp.l..h-tlNphLs.tcpL..hsh........................
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