GenomeNet

Database: Pfam
Entry: LmjF365940-deam
LinkDB: LmjF365940-deam
Original site: LmjF365940-deam 
#=GF ID   LmjF365940-deam
#=GF AC   PF14421.5
#=GF DE   A distinct subfamily of CDD/CDA-like deaminases
#=GF PI   CDD_CDA_1;
#=GF AU   Iyer LM, Zhang D, Aravind L
#=GF SE   Manual
#=GF GA   45.70 45.70;
#=GF TC   69.30 47.30;
#=GF NC   33.60 45.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   21890906
#=GF RT   Evolution of the deaminase fold and multiple origins of
#=GF RT   eukaryotic editing and mutagenic nucleic acid deaminases from
#=GF RT   bacterial toxin systems.
#=GF RA   Iyer LM, Zhang D, Rogozin IB, Aravind L;
#=GF RL   Nucleic Acids Res. 2011; [Epub ahead of print]
#=GF DR   INTERPRO; IPR032723;
#=GF CC   A distinct branch of the CDD/CDA-like deaminases prototyped by 
#=GF CC   Leishmania LmjF36.5940. Members of this family are widely
#=GF CC   distributed across several microbial eukaryotes such as
#=GF CC   kinetoplastids,  chlorophyte algae, stramenopiles and the
#=GF CC   alveolate Perkinsus. Domain  architectures suggest that these
#=GF CC   proteins might possess mRNA editing  or DNA mutagenizing
#=GF CC   activity [1].
#=GF SQ   68
#=GS Q38A89_TRYB2/370-497      AC Q38A89.1
#=GS D0N437_PHYIT/361-620      AC D0N437.1
#=GS K3X7R0_PYTUL/360-635      AC K3X7R0.1
#=GS X6NWX0_RETFI/12-193       AC X6NWX0.1
#=GS T0RET2_9STRA/307-526      AC T0RET2.1
#=GS W2YLS7_PHYPR/372-640      AC W2YLS7.1
#=GS C5KBD0_PERM5/165-215      AC C5KBD0.1
#=GS V5B3J9_TRYCR/369-492      AC V5B3J9.1
#=GS W4FWW5_9STRA/333-560      AC W4FWW5.1
#=GS W6L9Z6_9TRYP/266-396      AC W6L9Z6.1
#=GS C1N795_MICPC/486-700      AC C1N795.1
#=GS A0A0G4GFE1_VITBC/70-165   AC A0A0G4GFE1.1
#=GS X6MRZ3_RETFI/270-501      AC X6MRZ3.1
#=GS W7U454_9STRA/578-921      AC W7U454.1
#=GS A0A024TN09_9STRA/318-550  AC A0A024TN09.1
#=GS A0A0S4IPY9_BODSA/226-297  AC A0A0S4IPY9.1
#=GS Q4Q0G6_LEIMA/412-538      AC Q4Q0G6.1
#=GS W6L9Z6_9TRYP/394-461      AC W6L9Z6.1
#=GS V5B3J9_TRYCR/487-561      AC V5B3J9.1
#=GS A4IE07_LEIIN/127-253      AC A4IE07.1
#=GS M4BQJ0_HYAAE/354-656      AC M4BQJ0.1
#=GS A0A0L0FHB9_9EUKA/31-302   AC A0A0L0FHB9.1
#=GS S9TLD4_9TRYP/274-402      AC S9TLD4.1
#=GS A0A0G4EQ48_VITBC/40-135   AC A0A0G4EQ48.1
#=GS W6KP16_9TRYP/361-493      AC W6KP16.1
#=GS A4IE07_LEIIN/250-318      AC A4IE07.1
#=GS A0A024GRI2_9STRA/349-596  AC A0A024GRI2.1
#=GS Q4CXE8_TRYCC/369-492      AC Q4CXE8.1
#=GS B7GB54_PHATC/685-977      AC B7GB54.1
#=GS Q38A89_TRYB2/494-566      AC Q38A89.1
#=GS C5KBD0_PERM5/70-172       AC C5KBD0.1
#=GS Q4DNI7_TRYCC/487-561      AC Q4DNI7.1
#=GS Q4CXE8_TRYCC/487-561      AC Q4CXE8.1
#=GS C5KHT8_PERM5/164-214      AC C5KHT8.1
#=GS A0A0M0JEH7_9EUKA/250-416  AC A0A0M0JEH7.1
#=GS A0A0G4ECT7_VITBC/249-344  AC A0A0G4ECT7.1
#=GS Q4DNI7_TRYCC/369-492      AC Q4DNI7.1
#=GS K2NCU0_TRYCR/486-560      AC K2NCU0.1
#=GS H3GUA2_PHYRM/361-650      AC H3GUA2.1
#=GS W2PRR7_PHYPN/372-640      AC W2PRR7.1
#=GS A0A0M9G3M3_9TRYP/540-608  AC A0A0M9G3M3.1
#=GS A0A0N7L3D3_9STRA/339-619  AC A0A0N7L3D3.1
#=GS C5KHT8_PERM5/69-171       AC C5KHT8.1
#=GS C1EFE8_MICCC/391-596      AC C1EFE8.1
#=GS D7G3E7_ECTSI/557-885      AC D7G3E7.1
#=GS A0A061J7V9_TRYRA/488-561  AC A0A061J7V9.1
#=GS A4HQB2_LEIBR/418-544      AC A4HQB2.1
#=GS S9TLD4_9TRYP/398-468      AC S9TLD4.1
#=GS A0A023AZW5_GRENI/30-125   AC A0A023AZW5.1
#=GS A0A0G4GFE1_VITBC/164-210  AC A0A0G4GFE1.1
#=GS A4HQB2_LEIBR/540-610      AC A4HQB2.1
#=GS K2NCU0_TRYCR/368-491      AC K2NCU0.1
#=GS A0A067CZ46_SAPPC/307-527  AC A0A067CZ46.1
#=GS K0SZS5_THAOC/573-878      AC K0SZS5.1
#=GS W6KP16_9TRYP/490-557      AC W6KP16.1
#=GS A0A0N0P9C3_LEPSE/542-611  AC A0A0N0P9C3.1
#=GS X6LM34_RETFI/14-135       AC X6LM34.1
#=GS A0A0S4IPY9_BODSA/82-231   AC A0A0S4IPY9.1
#=GS A0A0N0P9C3_LEPSE/419-545  AC A0A0N0P9C3.1
#=GS G5AGH2_PHYSP/357-655      AC G5AGH2.1
#=GS V9EIB2_PHYPR/372-640      AC V9EIB2.1
#=GS A0A0W8CV57_PHYNI/361-629  AC A0A0W8CV57.1
#=GS A0A0M9G3M3_9TRYP/416-542  AC A0A0M9G3M3.1
#=GS A0A0G4IVG2_PLABS/332-537  AC A0A0G4IVG2.1
#=GS W4FZ70_9STRA/317-544      AC W4FZ70.1
#=GS A0A061J7V9_TRYRA/369-492  AC A0A061J7V9.1
#=GS X6N209_RETFI/83-179       AC X6N209.1
#=GS Q4Q0G6_LEIMA/534-603      AC Q4Q0G6.1
Q38A89_TRYB2/370-497                 .............rt--LDLKREGAKSFFTNITLEILQFr..sTMADCSWRKKDpMRQVVTSLMtyVDHKk..cHCNVTCGSRRHwsmhkpalssngngm......................snatfpdhswctcprsTVMAVNYELSTPSGSRCSEQNALGK-LAS-----------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------mgl..........
D0N437_PHYIT/361-620                 ..............a-LTQMIVREMRKFRDQFLAAEGE-....GEVAGFWLRKS.RKPVLAVLL..IEKP....AAELGGRPTIV.....................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGL..............................NLTAGG..nSSS.VT.SPT.ASED..tG............DDA....................................kR-Kepsqgasfdktast...............................................................................................stapaelhvveaanP--Qvlsvrvrpaavqsslssaa................tnnstvaaragrgrgrgrgKREL.........................................ETKNANL.........TSPRKP...................................kRPrTFSFDEVAEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQIM.............
K3X7R0_PYTUL/360-635                 ..............a-MTQTLVKEMRIFRDQFLQAEGE-....GEVGNFWLRKS.RKPVLAVLL..IEKE....--DAQGVKRLI.....................................................VHRGMNCEVSMPTGSLCAERNAIGSALASDPTLKRRALKMIGVLSL..............................NLEGGG...GSS.VQkREE.TTTS..vS............TTFadiphvg.......................kfqisklK--...........................................................................................................................---Eeatttetttlrgdneeasdlgvta.....varsqavsatsinvtgasslfirspKRRL.........................................EVENSNY.........QSPRKPkrprtfscddtsv..........eallsasesktdrNP.LAPCGACKEWLVKIAE.....ANPAFRVVTFDNS.RCRSVYVNQIM.............
X6NWX0_RETFI/12-193                  .tqvgnrnvlaaeaf------------------------....-----------.-QPILAIVV..IQKP....------NEPIE.....................................................YFRGVNMEVAMSTGSLCAERNAIGSAFVSDPSIRREYFKMVAVLQM.............................pNLPSTT..rMSK.LD.RDP.PPLRlekA............QHH.....................................--Y...........................................................................................................................SAST......................................................HRNQ.........................................AMLSQSNp.......fG--KNKlspsthlk...................vdedgledqNP.RGPCGACAEWLKKIAE.....VNPNFKIVTFSDV.KLAK-------flff.........
T0RET2_9STRA/307-526                 ...........plvl----RLVDEMKAFRDCFVDGQHL-....GEVGSFWLRKS.RKPVLAILL..IQKT....--LPNGETALV.....................................................VHRGMNCEVSMPTGSLCAERNAIGSALANDPTLHRNALKMIGVLSV..............................NLAPSS..sTTA.LP.LPR.TVSL..pTpimp....tvraA-Adcsspkakk..................pkrprtfscdGTT...........................................................................................................................PAVAs....................................................aLAEI.........................................SAPKKEV.........PAPEDR....................................NP.LGPCGACNEWLLKIAE.....ANPSFKIITFGSM.ECDSIYVHQ--ll...........
W2YLS7_PHYPR/372-640                 ..............a-MTQMIVREMRKFRDQFLAAEGE-....GEVAGFWLRKS.RKPVLAVLL..IEKP....AAELGGRPTIV.....................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGL..............................NLTAGG...NIS.VT.SPT.ASED..tA............DDKke................................psdG-Atfdkkt..............................................................................................................stavepaN--Sqvlpvrvrpaavqssrss..................aavnnlsvddagrgrgrgKRAL.........................................ETKNANL.........TSPRKPkrprtfsfdeva...........veemmrasappdrNP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m............
C5KBD0_PERM5/165-215                 ............ptk------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................------M.........NDGHTD....................................NP.LWPCGACSEWLKKIQQ.....SVPNFRVLAFDSV.EMNVIYE----rfl..........
V5B3J9_TRYCR/369-492                 ..............n-IVDLRKEPEGSFLSKLCPIIMSFr..qKNAHVSWRKKDpNRPVVTSLItyIDPEe..cDCQVDCSGRGRppalikpngrege..........................ekhprstwctctrsFVLAVNYELSTPSGSRCSEQNALGK-LAS-----------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------mgl..........
W4FWW5_9STRA/333-560                 ..............p-LVARAVDEIKAFRDQFVQGEHL-....GEVGQFWLRKS.RKPVLAVLL..VEKR....--TSSGDVQVV.....................................................VHRGMNCEVSMPTGSLCAERNAIGSALANDPTLLRQSLKMIAVLSVslhplklapppppslsstslllpappalilA----H...ATT.TT.VTT.----...-............--Avea..............................spktGRK...........................................................................................................................PKRP......................................................-RTIscdas..............................vpsiqaALDAVDAs.......aATEKDL....................................NP.LAPCGACNEWLLKIAE.....ANPSFKIVTFDSI.DCDSVYIHQ--ll...........
W6L9Z6_9TRYP/266-396                 ............qvv---PLAKEPADSFLWKVTRLIQGFr..dGHAHCSWRKHNpSRTVVTSVLtyVDVR....ACGCGGITPEAeeeeegerggaaalppip.................pekdigfparswcscprrWEVGVNYELSTPSGSRCSEQNAMGK-LAS-----------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------lgv..........
C1N795_MICPC/486-700                 ..............a-IISRMVDEMKKHRDAYVAAASEK...tNELGAFWLRKT.RKPVLAVLC..VRKK...gKTG----RGHE.....................................................FYRGVNLEVSMPTGSLCSERNVIGTALACDPTLRRADLFGVAVLSL..............................KKTGGE..gSGS.GN.AQKgGVIN...Gg..........vRDG.....................................GTA...........................................................................................................................PPTP......................................................VPGS.........................................SFAGGAS.........RNASYAndlsglgsgp................tcrpvaeddlNP.LHPCGACKEWLYKIAE.....VNPGFKVVMFTDA.SCEEVFVKTV-g............
A0A0G4GFE1_VITBC/70-165              .............pl---KRLVDEMRRFVNDWKSFEAA-....GEMDPFWHRKS.SKTVLAVVM..VVNK....------SGQEM.....................................................FYRGMNSEISLPSGSNCAERSAISTCISNSLDVRRSDFRAIAV---..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------ad...........
X6MRZ3_RETFI/270-501                 .............kd--VQKIVHEMESWKDDFSIKMKAP...kSEIETFWLRKS.YQPILAVVM..IQKP....------NEPIQ.....................................................YFRGVNMEVAMSTGSLCAERNAIGSAFVSDPSIRREYFKMVAVLQM.............................pDLSSAA..kISK.FD.REQ.SPQP...Syycy....hfffF-CfflflllfmhafppplrlekaqhhysafmhrnqtifnQSN...........................................................................................................................PFGN......................................................-RQS.........................................VDTKMNE.........KAPEDN....................................NP.RGPCGACSEWLKKIAE.....VNPNFKIVTFSDV.E----------litflfflp....
W7U454_9STRA/578-921                 ............ara---RLVAQEMLRYKEEVLLHYRQGl..cADLSTFWLRKT.EKPVLAVLL..VQKD....------RARPL.....................................................LYRGCNMEVSMPTGSLCAERNAIGSALAADLTLKRRDLKVVAVLSVsfg........................kngNTGGGGg.gGDG.GR.KPE.GTAK...Aldav....fasiDT-.....................................--AprvasqttdrnhsysdsctghsignaqprgllgprkgdagasertggsmmasvgdqegpwtpssrrtgaqeevfdglspprttiirsysvkdlngcgqdgafgkpspaecrgrphassmdsldPKS-......................................................----.........................................-------.........-----SkstspiiplsnlrvdgggrdqqgpgamtirveaddlNP.LKPCGACMEWLKKIAE.....KNPEFRVATFTDE.ACRGIYTEF--vs...........
A0A024TN09_9STRA/318-550             ..............p-IVTRLVNEVKSFRDQFVQGEHL-....GEVGQFWLRKS.RKPVLAVLL..IEKL....---VDGTPTIV.....................................................VHRGMNCEVSMPTGSLCAERNAIGSALANDPTLLRQSLKMIAVLSVtlhs.....................hpkqvA---MA...SAA.QPpCSS.T---...-............--Alpidapppvlvnvp.........ssiqpsnverspkaGRK...........................................................................................................................PKRPrtiscda.......................................svpaiqaaLTAV.........................................DAATAMA.........KAEKDL....................................NP.LAPCGACNEWLLKIAE.....ANPSFKIVTFDSI.DCDSVYIHQ--ll...........
A0A0S4IPY9_BODSA/226-297             ..........amgla------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................-TCN......................................................LREI.........................................FVHGDM-.........HNNEDP....................................NP.LFPCGVCENMLRRITHdvqkeYGGDVTLYMFDQVrEPKKLVCIPVQ.............
Q4Q0G6_LEIMA/412-538                 ..............t-IIDLKKEQPNTFFSNATRIIQNFc..rTHAHCSWRKHNpSRLVVTSVLtfVDVNk..cHCHLNGDNPEDthderidapitadie.......................amgtpsgswcqcmrgGVIAVNYELSTPSGSRCSEQNAMGK-LAS-----------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------lgv..........
W6L9Z6_9TRYP/394-461                 ............lgv------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................PTWS......................................................VREL.........................................FVHGA--.........-NVVNI....................................NP.LFPCGVCDNMLQKVDKdvrtrYGGEVRLFMFDET.VPSKVVYLPM-s............
V5B3J9_TRYCR/487-561                 ..........lasmg------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................--L...........................................................................................................................PTSA......................................................IREI.........................................FVHGEML.........GSKKDP....................................NP.LFPCGVCENMLRKVTRdvhdaYGGDVVLYMFDSTvNPKKLVYLPIN.............
A4IE07_LEIIN/127-253                 ..............s-IIDLKKEQPNTFFSNATRMIQSFc..rTHAHCSWRKHDpSRPVVTSVLtfVDVNk..cHCHLNGDNPENtheehidapipadie.......................emgtpsgswcqcmrrGVIAVNYELSTPSGSRCSEQNAMGK-LAS-----------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------lgv..........
M4BQJ0_HYAAE/354-656                 ..............a-MTQRIVVEMKTFRDQFLAAEGQ-....GELASFWLRKS.RKPVLAVLL..IEKA....ASRSNESPTVV.....................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGL..............................NLAGGDi.gSSDlVT.GST.PLIS...T............DQS.....................................EERvqedgkteeellqvhtsavttfveptl....................................................................vsgksgskttadvevavepdriqwtvsgP--Rlsedegakglilnde.......................cgqhcrasegcghgkrS--Reh.....................................vnEVTSRSL.........TKPKRPrtfscdelisd..............smresrtlpdrNP.LAPCGACKEWLVKIAE.....ANPSFRVITFDNA.HCRHVYINQI-i............
A0A0L0FHB9_9EUKA/31-302              svaretfqpwpchiv--------------------EDGD....SEINEFWLRKT.KKPVLSVLR..YTKP....------GEESQ.....................................................YVYGMNIEVSMPTGSLCSERNAIGTAIASDPSLKRKDFDMIAILSIsl..........................peLANAST...PAV.TP.NPA.RRDR..rS............TEL.....................................DTNqtdtnqtqtslttehgmlkgskgsa.........................................................................htlanvlsdvaqnagptttdgtksaA--Tskppgsqplmnavp..........................prgfyedclaplkrF--Nsdlqa..............................ltigneE-----Fiw.....pqEKKRTE...................................lNP.LDPCGSCMEWLRKIAE.....VNPDMKIVTFDSS.SCERLYVKNV-i............
S9TLD4_9TRYP/274-402                 .............cv--VNLSKEPPESFFSRVTNIIKSFsvegRNAHCSWRKNDpTRPLVTSVFtyVDVN....TCRCGDVSRVLnvdddasvraeldpvt.....................eniglpprvwctcarhYVVAVNYELSTPSGSRCSEQNAMGK-LAS-----------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------lgv..........
A0A0G4EQ48_VITBC/40-135              ...........plkr-----LVDEARRYVNEWKSLE---....SQMDSFWHRKS.SKIVLAVVM..VVEK....-------GRLR.....................................................FYRGMNSEISLPSGSNCAERSAISTCISNMLTVRRSDFRAIAVVD-..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------pkd..........
W6KP16_9TRYP/361-493                 ..............k-VTRLSKEPADSFLVRVTDIINGFr..aLHAHCSWRKHNpHRTVVTSILtyVDVR....GCQCGLLPPGSplrggdedddnafpalpsi...............ppgaaiglperswctcarrWEVGVNYELSTPSGSRCSEQNAMGK-LAS-----------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------lgv..........
A4IE07_LEIIN/250-318                 ............slg------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................--V...........................................................................................................................PTWG......................................................VREV.........................................FVHGR--.........-AAKEP....................................NP.LFPCGVCENMLRRVTKdvlahYGGDVTLYMFDAT.TPRKIVFLTI-p............
A0A024GRI2_9STRA/349-596             ..............p-MVQLVVQEMCIFRDQFLQAQ-GK....GEVESFWLRKS.RKPVLAVLL..VEKH....--EQDGSVRLL.....................................................VHRGMNCEVSMPTGSLCAERNAIGSALAQDPTLCRRSLKMIAVLGV..............................NLLESK...TSV.IT.TTR.TITD...ScelnpprteslsD--.....................................--Nvynniithksqneglklssir................................................................................atcqmtlsrafecereaghalsPSRP......................................................KRPRtfs...................................iddYTIGESQ........lSKIGDR....................................NP.LAPCGACKEWLMKIAE.....ANPSFRVITFENA.DCHNVYISQIM.............
Q4CXE8_TRYCC/369-492                 ..............n-IVDLRKEPEGSFLSKLCPIIMSFr..qKNAHVSWRKKDpNRPVVTSLItyIDPEe..cDCQVDCSGRGRppalmkpngrere..........................ekhprstwctctrsFVLAVNYELSTPSGSRCSEQNALGK-LAS-----------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------mgl..........
B7GB54_PHATC/685-977                 ..............p-YRHLVIDEMKAFQAEMIKTLQGQ....NDIHRFWLRKT.HKPVLAVLL..VEQE....-------GQPI.....................................................LYRGTNMEVSMPTGSLCAERNVIGTALAANPSLRRQDLKMIAVLAVpwq.......................ekltDMGSAGtlrSSE.EP.FPA.LASS..sAsltsi.mctttlES-.....................................--Gegrktsigseheewilssapaggedgstgattnktrl................................................ppakselgnsfdlvdsgvpssssgvastapdrqpnddiPSTP......................................................VRRI.........................................ALFSRSG.........TVARKSqqavvl.......................vqstrdlNP.LPPCGACNEWLKKIAE.....CNPYFCVLTFTDA.ECHGVYCTPCQ.............
Q38A89_TRYB2/494-566                 ...........smgl------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................PTCA......................................................VREV.........................................FVHGEHQ.........GSKKDP....................................NP.LFPCGVCENMLRKVAHdvleiHGGDVMLYMYDSThNPKRLVYLPI-t............
C5KBD0_PERM5/70-172                  ..........ptavl------ANKLREYMERTTADG---....FQPEPFFHRKS.GKLVLSMLH..VRME....------DGSDE.....................................................FFEGINGEVSLPTGSLCSERAAIAHARSVHPRINRGMFMGIAVIDV..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------ptkmndgh.....
Q4DNI7_TRYCC/487-561                 ..........lasmg------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................--L...........................................................................................................................PTSA......................................................IREI.........................................FVHGEML.........GSKKDP....................................NP.LFPCGVCENMLRKVTRdvhdaYGGDVVLYMFDSTvNPKKLVYLPIN.............
Q4CXE8_TRYCC/487-561                 ..........lasmg------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................--L...........................................................................................................................PTSA......................................................IREI.........................................FVHGEML.........GSKKDP....................................NP.LFPCGVCENMLRKVTRdvhdtYGGDVVLYMFDSTvNPKKLVYLPIN.............
C5KHT8_PERM5/164-214                 ............ptk------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................------M.........NDGHTD....................................NP.LWPCGACSEWLKKIQE.....SVPNFRVLAFDSI.EMNVIYE----rfl..........
A0A0M0JEH7_9EUKA/250-416             ...........eekg-----LVDEMVQYKRQFEAVRDSN...tHELGTFWLRKT.GKAVLAVLL..TKSP....------LGELT.....................................................FWRGMNVEVSMPTGTLCAERNAIGNALAGDHSVHRRDMLAVAVLSV..............................TL----...---.--.---.----...-............---.....................................-SP...........................................................................................................................PKHE......................................................VTDQ.........................................ALERT--.........TSPDDEv.................................alNP.LDPCGACMEWLRKIAE.....VNPDFKVLTFTST.SCEKVFITPI-g............
A0A0G4ECT7_VITBC/249-344             ............plk----RIVDEARRYVNEWKSLE---....GQMDSFWHRKS.SKIVLAVVM..VVDK....------NGQER.....................................................FYRGMNSEISLPSGSNCAERAAISACISNSLTVRRSDFRAIAVVD-..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------pk...........
Q4DNI7_TRYCC/369-492                 ..............n-IVDLRKEPEGSFLSKLCPIIMSFr..qKNAHVSWRKKDpNRPVVTSLItyIDPEe..cDCQVDCSGRGRppalikpngrere..........................ekhprstwcnctrsFVLAVNYELSTPSGSRCSEQNALGK-LAS-----------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------mgl..........
K2NCU0_TRYCR/486-560                 ..........lasmg------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................--L...........................................................................................................................PTSA......................................................IREI.........................................FVHGEML.........GSKKDP....................................NP.LFPCGVCENMLRKVTRdvhdtYGGDIVLYMFDSTvNPKKLVYLPIN.............
H3GUA2_PHYRM/361-650                 ..............a-LTQMIVREMRMFRDQFLAAEGE-....GEVASFWLRKS.RKPVLAVLL..IEKP....AAVAGERPTIV.....................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGL..............................NLSGSG...SNV.ISpTPS.ETRG...Sereg....gavgDDG.....................................NKKpseaqaaa...........................................................................................................gptfdqptS--Tstagptapalpvrirpacvqsspep....pdankpaerqgsvggvgrgrgrgrgKRAL.........................................ENKNANL.........TSPRKPkrprtfsfdeva...........veemmrasappdrNP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m............
W2PRR7_PHYPN/372-640                 ..............a-MTQMIVREMRKFRDQFLAAEGE-....GEVAGFWLRKS.RKPVLAVLL..IEKP....AAELGGRPTIV.....................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGL..............................NLTAGG...NIS.VT.SPT.ASED...T............ADD.....................................KKE...........................................................................................................................PSDSatfdkktstavepansqvlpvrvrpt..avqssrssaavnnlsvddagrgrgrgKRAL.........................................ETKNANL.........TSPRKPkrprtfsfdeva...........veemmrasappdrNP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m............
A0A0M9G3M3_9TRYP/540-608             ............lgv------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................PTWG......................................................VREV.........................................FVHGM--.........NIKKEA....................................NP.LFPCGVCENMLQKVTKdvmshYGGDVTLYMFDAT.HPRKIVFLTI-p............
A0A0N7L3D3_9STRA/339-619             ..............a-MTQMIVNEMQQFRDQFLEAEGQ-....GEVAGFWLRKS.RKPVLAVLL..IEKP....-AIDGGRPTIV.....................................................MQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGL..............................NLTAGG..nTSP.TT.SDD.RVQD...Thtiae..tiettD--.....................................-SAttnrtvdttkaqisavqtcrshseqssf..................................................................ssvltvnstflsiqnarqhddvaiekergQTRR......................................................KRQL.........................................RITNANL.........RSPRKPkrprtfsfddma...........viemmrasepldrNP.LAPCGACKEWLVKIAE.....ANPSFRVITFENA.RCRNVYINQL-m............
C5KHT8_PERM5/69-171                  ..........ptavl------ANKLRDYMERTTADG---....FQPDPFFHRKS.GKLVLSMLH..VRME....------DGRDE.....................................................FFEGINGEVSLPTGSLCSERAAIAHARSVHPRINRGMFMGIAVIDV..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------ptkmndgh.....
C1EFE8_MICCC/391-596                 ..............r-LVTGMVQEMKKHRDVFLSMSHSK....HELGEFWLRKT.QKPVLAVLC..VRRRrdgpDDAAHGDAKPQ.....................................................YFRGVNLEVSMPTGSLCSERNAIGNALASDPALRRKDLFGIAVLSLgkg........................digATSGGGv.gGGA.MS.RES.SFVN..lAql........aaGN-.....................................GGD...........................................................................................................................DLSL......................................................CRPV.........................................TGGG---.........GGRGDL....................................NP.LKPCGACKEWLLKIAE.....VNPGFKVLMFGDV.SCDDVYIKNV-s............
D7G3E7_ECTSI/557-885                 ...............AYTRQAFDAPAG-DANGEAVVGGDt..rDDLASFWLRKT.KKPVLAVLL..VQKK....------GGRPQ.....................................................LFRGTNMEVSMPTGSLCAERNVIGSALTSDLSLLRRDIKAVAVLSVahl.......................ggppASTATT...AAA.VP.IDE.RKEG...Asltg....itavDSG.....................................GGRsgwpgaagmgsavgssl........................................................................................ttscapsplsltpamkvsPKSAllrtetgagaedke..........................rlegvrqvrrktkvV--RsiastpkrgvgsggiaaggwekspltdsgggggggrgdgggGMYSDDQgggggsnhhRHPRTSrssivah.....................vppetlcsNP.LKPCGACMEWLKKIAE.....VNPDFKVITFTDS.RCGGVYIEDV-a............
A0A061J7V9_TRYRA/488-561             ...........asmg------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................--L...........................................................................................................................PTSA......................................................IREV.........................................FVHGENR.........RAQTDP....................................NP.LFPCGVCENMLRRVTRdvyetYGGDVVLYMFDSTvNPKKLVYLPV-n............
A4HQB2_LEIBR/418-544                 ..............n-IIDLKKEHPNSFFSNATRMIQHFc..rTRAHCSWRKHDpTRPVVTSVLtfVDVNr..cHCHRNGDNPYNtheehieasfpsdie.......................amgtpsgawcqcmrrGVIAVNYELSTPSGSRCSEQNAMGK-LAS-----------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------lgv..........
S9TLD4_9TRYP/398-468                 ...........aslg------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................--V...........................................................................................................................PTWS......................................................VREV.........................................FVYGL--.........NPKKES....................................NP.LFPCGVCENMLQKVNSdiskhYGNEATLFMFDAT.KPHKVVYLPV-a............
A0A023AZW5_GRENI/30-125              ......edtkflvgh-------------MRQFAQDYQA-....AKPDTYWHRKS.GQVVLAVLL..LRIH....-------GKLQ.....................................................TVRGINSELSLPSGSVCAERAAIAAALAQHLSIARSDFVSIAVLA-..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------pnna.........
A0A0G4GFE1_VITBC/164-210             ............adp------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........---KDE...................................lNP.IAPCGVCDEWLQKIQE.....ESPGFSIVTFTTS.ECNEI------rerc.........
A4HQB2_LEIBR/540-610                 ...........aslg------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................--V...........................................................................................................................PTWG......................................................VREV.........................................FVHGM--.........ASKKEA....................................NP.LFPCGVCENMLQRVTKdvlahYGGDITLYMFDAT.TPRKIVFLPI-p............
K2NCU0_TRYCR/368-491                 ..............n-IVDLRKEPEGSFLSKVCPIIMSFr..qKNAHVSWRKKDpNRPVVTSLItyIDPDe..cNCQVDCSGRGRpptlmepnsrege..........................ekhprstwctctrsFVLAVNYELSTPSGSRCSEQNALGK-LAS-----------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------mgl..........
A0A067CZ46_SAPPC/307-527             ..............p-LVQRLVDEMKSFRDCFVDGQHL-....GEVGSFWLRKS.RKPVLAILL..IQKT....--LPTGETALV.....................................................VHRGMNCEVSMPTGSLCAERNAIGSALANDPTLHRNALKMIGVLSVn............................lAPPSTS...TSS.LP.LPR.TVSL..pTpitp...tvraaT-Dcsspkakkp...................krprtfscdGTT...........................................................................................................................PAVAs....................................................aLAEI.........................................SAPKKEV.........PAPEDR....................................NP.LGPCGACNEWLLKIAE.....ANPSFKIITFGSM.ECDSIYVHQ--ll...........
K0SZS5_THAOC/573-878                 ............evs----RVTVEMKAFRVEFLQSVKEGg..rSDLREFWLRKT.RKPVLAVLL..VQKP....------NHEPV.....................................................LYRGTNMEVSMPTGSLCAERNVIGTALASDPGLKREDLKMVAVLSVrmpkdrtyrni.......lpppggmsfcqpTATATS...SSD.LA.KEV.EARP...K............QDV.....................................GMKktlsmssftsiaeglpsp......................................................................................encvneswemdllsgfdktPTAEeaayvetpkegmlipeln.................lrnrpsdasdgsvsgsstpKRRI.........................................ALYKKKN.........RNKAGGkrqtlvvqql...............eadligflqdmNP.LKPCGACNEWLKKIAE.....SNPHFKVLTFTDE.NQAGVYVMPCQ.............
W6KP16_9TRYP/490-557                 ............slg------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................--V...........................................................................................................................PTWS......................................................VREL.........................................FVHGS--.........--SEHV....................................NP.LFPCGVCDNMLQRVAKdvrtrYGGEIRLYMFDAT.VPSKVVSLP--ms...........
A0A0N0P9C3_LEPSE/542-611             ............slg------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................--V...........................................................................................................................PTWG......................................................VREV.........................................FVHVM--.........NAKKEA....................................NP.LFPCGVCENMLQKVTKdvmshYGGDVTLYMFDAT.QPRKIVFLTI-p............
X6LM34_RETFI/14-135                  ............kdv---QKIVYEMERWKDDFVIKMKAP...kSEIETFWLRKS.FQPILAIVV..IQKP....------NEPIE.....................................................YFRGVNMEVAMSTGSLCAERNAIGSAFVSDPSIRREYFKMVAVLQM.............................pNLPSTT..rM--.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------skldrelspqpsg
A0A0S4IPY9_BODSA/82-231              ............rti---DLSKLPASNFFKKVVKITLDFr..gSNAHKSWRKQDaTRPIVTSLItyVDST....TCFCQAHGTISasqtpslgpmgrgssslsspqrqgstggtshyidasaaagaypenswcrcprkWELAVNYELSTPSGSRCSEQNCLGK-LA------------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------amglat.......
A0A0N0P9C3_LEPSE/419-545             ..............n-IVDLKKEDSRSFFSVVTRMMLNFp..tVHAHKSWRKHDsTRPVVTSVLtfVDVNt..cHCHRCGHSPENaceehidavipadia.......................vvgvprgswchctrrAVIAVNYELSTPSGSRCSEQNAMGK-LAS-----------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------lgv..........
G5AGH2_PHYSP/357-655                 ..............a-MTQMIVREMRIFRDQFLAAEGD-....GEVASFWLRKS.RKPVLAVLL..IEKP....AAVVGDRPTIV.....................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLSRRALKMIAVLGL..............................NLTAEG..pSSN.VT.SPT.ASET..rGsereg.patctkD--.....................................--Tkgngngkrdp......................................................................................................sdaeatfdkptS--TstepgpelvaqpqpltvrirpageqsspernslslaaasprarshvggagrgrgKRGP.........................................ETKNANL.........TSPRKPkrprtfsmddva...........vdemlrasgppdrNP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m............
V9EIB2_PHYPR/372-640                 ..............a-MTQMIVREMRKFRDQFLAAEGE-....GEVAGFWLRKS.RKPVLAVLL..IEKP....AAELGGRPTIV.....................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGL..............................NLTAGG...NIS.VT.SPT.ASED..tA............DDKke................................psdG-Atfdkkt..............................................................................................................stavepaN--Sqvllvrvrpaavqssrss..................aavnnlsvddagrgrgrgKRAL.........................................ETKNANL.........TSPRKPkrprtfsfdeva...........veemmrasappdrNP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m............
A0A0W8CV57_PHYNI/361-629             ...............AITQMIVREMRKFRDQFLAAEGE-....GEVAGFWLRKS.RKPVLAVLL..IEKP....AAELGGRPTIV.....................................................VQRGMNCEVSMPTGSLCAERNAIGSALASDPTLTRRALKMIAVLGL..............................NLTAGG...NIS.VT.SPT.ASED..tA............DDKke................................psdG-Atfdkkt..............................................................................................................stavepaN--Sqvlpvrvrpaavqssrss..................aavnnlsvddagrgrgrgKRAL.........................................ETKNANL.........TSPRKPkrprtfsfdeva...........veemmrasappdrNP.LAPCGACKEWLVKIAE.....ANPSFRVVTFENS.RCRNVYINQL-m............
A0A0M9G3M3_9TRYP/416-542             ..............n-VIDLKREDDDSFFIVVTRMILNFr..tHHAHNSWRKHDpTRPVVTSVLtfVDVNe..cHCHRNGGDANNtieehidavipddta.......................vvgvpsgswcncprrAVIAVNYELSTPSGSRCSEQNAMGK-LAS-----------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------lgv..........
A0A0G4IVG2_PLABS/332-537             ...........lhlg-----LVEKMKERRQAFVLALRND....HELRAFWLRKT.FKPVLSVLL..VMKP....------GGVPQ.....................................................YFSGMNMEVSMPTGSLCAERNAIGNALAQDPTLHREHFKAMAVLSV..............................SMGSAD...PSN.GD.STS.THHW..hT............DVAs...................................pPNS...........................................................................................................................PTLAad.................................................awdDRRF.........................................NIRPTRSq......tmRHATTQsvsp...........................ylralNP.INPCGACKEWLKKIAL.....VNPDFVVLTFPSM.ICDSVFVRPV-l............
W4FZ70_9STRA/317-544                 ..............p-LVARAVDEIKAFRDQFVQGEHL-....GEVGQFWLRKS.RKPVLAVLL..VEKR....--TSSGDVQVV.....................................................VHRGMNCEVSMPTGSLCAERNAIGSALANDPTLLRQSLKMIAVLSVslhplklapppppslsstslllpappalilA----H...ATT.TT.VTT.----...-............--Avea..............................spktGRK...........................................................................................................................PKRP......................................................-RTIscdas..............................vpsiqaALDAVDAs.......aATEKDL....................................NP.LAPCGACNEWLLKIAE.....ANPSFKIVTFDSI.DCDSVYIHQ--ll...........
A0A061J7V9_TRYRA/369-492             ..............n-VVDLMREPEGSFILSVCPIIMSFr..qTHAHASWRKNDpNRPVVTSLItyIDPD....ECHCQADTGQRagspalmssgghkr........................qekyprntwctcnrsYVIAVNYELSTPSGSRCSEQNALGK-LAS-----------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------mgl..........
X6N209_RETFI/83-179                  ..............q-ITYLLIKEMEKYLKEFHAKERE-....DKMDPFWNRKS.FKSVLAVLM..VRKR....QDNDNNNNNNNnnnnn..........................................nskqyvFYRGRNTEISLPVGSHCAERAAIVT---------------------..............................------...---.--.---.----...-............---.....................................---...........................................................................................................................----......................................................----.........................................-------.........------....................................--.----------------.....-------------.-----------lcq..........
Q4Q0G6_LEIMA/534-603                 ...........aslg------------------------....-----------.---------..----....-----------.....................................................----------------------------------------------..............................------...---.--.---.----...-............---.....................................--V...........................................................................................................................PTWG......................................................VREV.........................................FVHGM--.........-AATEP....................................NP.LFPCGVCENMLRRVTKdvlahYGGDVTLYMFDAT.TPRKIVFLPI-p............
#=GC seq_cons                        ..............s....hhhp..ttahpphh.h........tphtt.Wh++s.t+sVlsslh..lp............ts........................................................h.huhNhElShPoGShCuEpNAlGp.lus.......................................................................................................................................................................................................................................................................................................................................................................................tp.....................................NP.lhPCGsCtphL.+lsc.....hssthhlhhFps..p.ptlh.....h............
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