#=GF ID Lysis_col
#=GF AC PF02402.11
#=GF DE Lysis protein
#=GF AU Mian N, Bateman A
#=GF SE Pfam-B_1555 (release 5.4)
#=GF GA 25.00 25.00;
#=GF TC 57.10 57.00;
#=GF NC 22.10 21.60;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 3323826
#=GF RT Nucleotide sequences from the colicin E8 operon: homology with
#=GF RT plasmid ColE2-P9.
#=GF RA Uchimura T, Lau PC;
#=GF RL Mol Gen Genet 1987;209:489-493.
#=GF DR INTERPRO; IPR003059;
#=GF DR TC; 9.B.41;
#=GF CC These small bacterial proteins are required for colicin release
#=GF CC and partial cell lysis. This family contains lysis proteins for
#=GF CC several different forms of colicin. Swiss:Q02112 has been
#=GF CC included in this family, the similarity is not highly
#=GF CC significant, however it is also a short protein, that is
#=GF CC involved in secretion of other proteins (Bateman A pers. obs.).
#=GF CC This family includes a signal peptide motif and a lipid
#=GF CC attachment site.
#=GF SQ 52
#=GS LYS9_ECOLX/1-47 AC P15176.1
#=GS C8URJ5_ECO1A/1-47 AC C8URJ5.1
#=GS B7LIF6_ECO81/1-45 AC B7LIF6.1
#=GS B9VMA2_ECOLX/1-47 AC B9VMA2.1
#=GS H4Z6A9_ECOLX/1-38 AC H4Z6A9.1
#=GS Q7B9M5_ESCFE/1-45 AC Q7B9M5.1
#=GS C8SXB4_KLEPR/1-49 AC C8SXB4.1
#=GS LYS5_ECOLX/1-47 AC P13344.1
#=GS Q51646_9ZZZZ/1-39 AC Q51646.1
#=GS E1HZG3_ECOLX/1-47 AC E1HZG3.1
#=GS D8BRC8_ECOLX/1-45 AC D8BRC8.1
#=GS LYS4_ECOLX/1-45 AC P09181.1
#=GS Q2PWZ0_KLEPN/1-49 AC Q2PWZ0.1
#=GS Q7B9M6_ESCFE/1-45 AC Q7B9M6.1
#=GS D8A0W2_ECOLX/1-45 AC D8A0W2.1
#=GS LYS0_ECOLX/1-49 AC P02987.1
#=GS A8ARS6_CITK8/1-49 AC A8ARS6.1
#=GS LYS2_ECOLX/1-47 AC P06963.1
#=GS Q9XB45_ECOLX/1-44 AC Q9XB45.1
#=GS LYS6_ECOLX/1-47 AC P13345.1
#=GS G8EAZ9_CITFR/1-44 AC G8EAZ9.1
#=GS LYS7_ECOLX/1-47 AC Q03709.1
#=GS B5TQV1_ECOLX/12-58 AC B5TQV1.1
#=GS D2TV60_CITRI/1-40 AC D2TV60.1
#=GS E9YMY4_ECOLX/1-47 AC E9YMY4.1
#=GS F4U3X4_ECOLX/1-47 AC F4U3X4.1
#=GS Q9RMR6_KLEPN/1-49 AC Q9RMR6.1
#=GS H4ZNR9_ECOLX/1-47 AC H4ZNR9.1
#=GS LYS8_ECOLX/1-47 AC P10099.1
#=GS O52991_ECOLX/1-48 AC O52991.1
#=GS Q79D20_ECOLX/1-45 AC Q79D20.1
#=GS Q7B490_ECOLX/1-47 AC Q7B490.1
#=GS Q9XBT4_KLEPN/1-44 AC Q9XBT4.1
#=GS D7XGH6_ECOLX/1-47 AC D7XGH6.1
#=GS Q57131_ECOLX/19-43 AC Q57131.1
#=GS O24683_SHIBO/1-45 AC O24683.1
#=GS E6BTB6_ECOLX/1-47 AC E6BTB6.1
#=GS LYS3_SHISO/1-45 AC P21185.1
#=GS E9VI30_ECOLX/1-30 AC E9VI30.1
#=GS F9CTU2_ECOLX/1-45 AC F9CTU2.1
#=GS LYS1_CITFR/1-44 AC P06962.1
#=GS Q51611_9ZZZZ/1-45 AC Q51611.1
#=GS LYS3_ECOLX/1-45 AC P05821.1
#=GS H5ANA7_ECOLX/1-47 AC H5ANA7.1
#=GS Q47111_ECOLX/1-47 AC Q47111.1
#=GS C8URK8_ECO1A/1-48 AC C8URK8.1
#=GS H5DU97_ECOLX/1-47 AC H5DU97.1
#=GS Q47127_ECOLX/1-43 AC Q47127.1
#=GS A4SH39_SHISS/1-45 AC A4SH39.1
#=GS H4Z6A1_ECOLX/1-47 AC H4Z6A1.1
#=GS E1JFJ0_ECOLX/1-47 AC E1JFJ0.1
#=GS Q46785_ECOLX/1-43 AC Q46785.1
LYS9_ECOLX/1-47 ..MK..KITGIILLLLA..aIILAACQANYIRDVQGGTVSPSSSAELTGLATQ.
C8URJ5_ECO1A/1-47 ..MK..KITGIILLLLA..vIILAACQANYIRDVQGGTVSPSSTAEVTGLATQ.
B7LIF6_ECO81/1-45 ..MK..KITWIILLLLA..aIILAACQANYIRDVQGGTVSPSSSAELTGL---g
B9VMA2_ECOLX/1-47 ..MK..KITGIILLLLA..aIILAACQANYIRDVQGGTVSPSSSAELTGLATQ.
H4Z6A9_ECOLX/1-38 ..--..------MLLAA...IILAACQANYIRDVQGGTVSPSSSAELTGLATQ.
Q7B9M5_ESCFE/1-45 ..MR..KRFFVGIFAIN...-LLVGCQANYIRDVQGGTVAPSSSSKLTGISVQ.
C8SXB4_KLEPR/1-49 ..MKkvKTIFLLILIAS..gFLLVACQANYIRDVQGGTVAPSSSSELTGIAVQ.
LYS5_ECOLX/1-47 ..MK..KITWIILLLLA..aIILAACQANYIHDVQGGTVSPSSSAELTGLATQ.
Q51646_9ZZZZ/1-39 ..MK..KITGIILLLLA..vIILSACQANYIRDVQGGTVSPSST---------a
E1HZG3_ECOLX/1-47 ..MK..KITGIILLLLA..vIILSACQANYIRDVQGGTVSPSSTAEVTGLATQ.
D8BRC8_ECOLX/1-45 ..MR..KRFFVGIFAIN...-LLVGCQANYIRDVQGGTVAPSSSSKLTGISVQ.
LYS4_ECOLX/1-45 ..MC.gKILLILFFIMT...--LSACQVNHIRDVKGGTVAPSSSSRLTGLKL-s
Q2PWZ0_KLEPN/1-49 ..MKkvKVVFLFILIFS..gFLLVACQANYIRDVQGGTVAPSSSSELTGIAVQ.
Q7B9M6_ESCFE/1-45 ..MR..KRFFVGIFAIN...-LLVGCQANYIRDVQGGTIAPSSSSKLTGIAVQ.
D8A0W2_ECOLX/1-45 ..MR..KRFFVGIFAIN...-LLVGCQANYIRDVQGGTVAPSSSSKLTGISVQ.
LYS0_ECOLX/1-49 ..MKkaKAIFLFILIVS..gFLLVACQANYIRDVQGGTVAPSSSSELTGIAVQ.
A8ARS6_CITK8/1-49 ..MKkvKVVFLFILIFS..gFLLVACQANYIRDVQGGTVAPSSSSELTGIAVQ.
LYS2_ECOLX/1-47 ..MK..KITGIILLLLA..vIILSACQANYIRDVQGGTVSPSSTAEVTGLATQ.
Q9XB45_ECOLX/1-44 ..MK..KIIICAISLGI...MLLAACQVNNVRDTGGGAVSPSST--VTGVSM-g
LYS6_ECOLX/1-47 ..MK..KITGIILLLLA..vIILAACQANYIRDVQGGTVSPSSTAELTGVETQ.
G8EAZ9_CITFR/1-44 ..MK..KIIICVILLAI...MLLAACQVNNVRDTGGGSVSPSSI--VTGVSM-g
LYS7_ECOLX/1-47 ..MK..KITGIILLLLA..aIILAACQANYIRDVQGGTVSPSSTAELTGVETQ.
B5TQV1_ECOLX/12-58 ..MK..KITGIILLLLA..vIILSACQANYIRDVQGGTVSPSSTAEVTGLATQ.
D2TV60_CITRI/1-40 mi--..-------FAISpgiMLLAACQVNNVRDTGGGSVSPSST--VTGVSM-g
E9YMY4_ECOLX/1-47 ..MK..KITGIILLLLA..vIILAACQANYIRDVQGGTVSPSSSAELTGLETQ.
F4U3X4_ECOLX/1-47 ..MK..KITGIILLLLA..vIILAACQANYIRDVQGGTVSPSSTAEVTGLATQ.
Q9RMR6_KLEPN/1-49 ..MKkvKTIFLFILIAS..gFLLVACQANYNRDVQGGTVAPSSSSELTGIAVQ.
H4ZNR9_ECOLX/1-47 ..MK..KITWIILLLLA..aIILAACQANYIRDVQGGTVSPSSSAELTGLATQ.
LYS8_ECOLX/1-47 ..MK..KITGIILLLLA..vIILAACQANYIRDVQGGTVSPSSTAEVTGLATQ.
O52991_ECOLX/1-48 .m-K.kKIGGSMILVLA..vLCLTACQANYVRDVQGGTIAPSSSSKLIGVAVQ.
Q79D20_ECOLX/1-45 ..MR..KRFFVGIFAIN...-LLVGCQANYIRDVQGGTVAPSSSSKLTGISVQ.
Q7B490_ECOLX/1-47 ..MK..KITGIILLLLA..vIILAACQANYIRDVQGGTVSPSSTAEVTGLATQ.
Q9XBT4_KLEPN/1-44 ..MK..KLLFLGVVTVT...VVLAACQVNNVRDTGGGAVSPSST--VTGVTLD.
D7XGH6_ECOLX/1-47 ..MK..KITGIILLLLA..vIILSACQANYIRDVQGGTVSPSSTAEVTGLATQ.
Q57131_ECOLX/19-43 ..--..-----------...--------NYIRDVQGGTVAPSSSSELTGIAVQ.
O24683_SHIBO/1-45 ..MK..KILSGGMVVLM...VFLSGCQANYIRDVQGGTVAPSSS-ELTGISVQ.
E6BTB6_ECOLX/1-47 ..MK..KITGIILLLLA..vIILSACQANYIRDVQGGTVSPSSTAEVTGLATQ.
LYS3_SHISO/1-45 ..MR..KRFFVGIFAIN...-LLVGCQANYIRDVQGGTVAPSSSSKLTGISVQ.
E9VI30_ECOLX/1-30 mk--..----IIIFLIT..iLFLSGCQANYIRDVQGGTVA-------------.
F9CTU2_ECOLX/1-45 ..MR..KRFFVGIFAIN...-LLVGCQANYIRDVQGGTVAPSSSSKLTGISVQ.
LYS1_CITFR/1-44 ..MK..KIIICVILLAI...MLLAACQVNNVRDTGGGSVSPSSI--VTGVSM-g
Q51611_9ZZZZ/1-45 ..MR..KRFFVGIFAIN...-LLVGCQANYIPDVQGGTIAPSSSSKLTGIAVQ.
LYS3_ECOLX/1-45 ..MR..KRFFVGIFAIN...-LLVGCQANYIRDVQGGTIAPSSSSKLTGIAVQ.
H5ANA7_ECOLX/1-47 ..MK..KITGIILLLLA..aIILAACQANYIRDVQGGTVSPSSSAELTGLATQ.
Q47111_ECOLX/1-47 ..MK..KITGIILLLFA..aIILAACQANYIRDVQGGTVSPSSTAELTGVETQ.
C8URK8_ECO1A/1-48 ..MK.kEIGGSMILVLA..vLCLTACQANYVRDVQGGTIAPSSSSKLIGVAVQ.
H5DU97_ECOLX/1-47 ..MK..KITWIILLLLA..aIILAACQANYIRDVQGGTVSPSSSAELTGLATQ.
Q47127_ECOLX/1-43 .m--..KITFLIITILS...--LSGCQANYIRDVQGGTVAPSSSSELTGIAVQ.
A4SH39_SHISS/1-45 ..MR..KRFFVGIFAIN...-LLVGCQANYIRDVQGGTVAPSSSSKLTGISVQ.
H4Z6A1_ECOLX/1-47 ..MK..KITGIILLLLA..aIILAACQANYIRDVQGGTVSPSSSAELTGLATQ.
E1JFJ0_ECOLX/1-47 ..MK..KITGIILLLLA..vIILSACQANYIRDVQGGTVSPSSTAEVTGLATQ.
Q46785_ECOLX/1-43 mk--..----IIIFLIT..iLFCSGCQANYIRDVQGGTVAPSSSSELTGIAVQ.
#=GC seq_cons ..MK..KlhhlhlLllu..hhlLuACQANYIRDVQGGTVuPSSSuELTGlusQ.
//
