GenomeNet

Database: Pfam
Entry: MAM
LinkDB: MAM
Original site: MAM 
#=GF ID   MAM
#=GF AC   PF00629.19
#=GF DE   MAM domain, meprin/A5/mu
#=GF AU   Bateman A
#=GF SE   Prosite
#=GF GA   21.90 21.90;
#=GF TC   22.00 22.00;
#=GF NC   21.80 21.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   MAM_domain
#=GF RN   [1]
#=GF RM   8387703
#=GF RT   An adhesive domain detected in functionally diverse receptors. 
#=GF RA   Beckmann G, Bork P; 
#=GF RL   Trends Biochem Sci. 1993;18:40-41.
#=GF RN   [2]
#=GF RM   17761881
#=GF RT   Structure of a tyrosine phosphatase adhesive interaction reveals
#=GF RT   a spacer-clamp mechanism.
#=GF RA   Aricescu AR, Siebold C, Choudhuri K, Chang VT, Lu W, Davis SJ,
#=GF RA   van der Merwe PA, Jones EY;
#=GF RL   Science. 2007;317:1217-1220.
#=GF RN   [3]
#=GF RM   16456543
#=GF RT   Molecular analysis of receptor protein tyrosine phosphatase
#=GF RT   mu-mediated cell adhesion.
#=GF RA   Aricescu AR, Hon WC, Siebold C, Lu W, van der Merwe PA, Jones
#=GF RA   EY;
#=GF RL   EMBO J. 2006;25:701-712.
#=GF RN   [4]
#=GF RM   22988105
#=GF RT   Structural basis for the sheddase function of human meprin beta
#=GF RT   metalloproteinase at the plasma membrane.
#=GF RA   Arolas JL, Broder C, Jefferson T, Guevara T, Sterchi EE, Bode W,
#=GF RA   Stocker W, Becker-Pauly C, Gomis-Ruth FX;
#=GF RL   Proc Natl Acad Sci U S A. 2012;109:16131-16136.
#=GF DR   INTERPRO; IPR000998;
#=GF DR   PROSITE_PROFILE; PS50144;
#=GF DR   PROSITE; PDOC00604;
#=GF CC   An extracellular domain found in many receptors [1]. The MAM
#=GF CC   domain along with the associated Ig domain in type IIB receptor
#=GF CC   protein tyrosine phosphatases forms a structural unit (termed
#=GF CC   MIg) with a seamless interdomain interface. It plays a major
#=GF CC   role in homodimerisation of the phosphatase ectoprotein and in
#=GF CC   cell adhesion [2,3]. MAM is a beta-sandwich consisting of two
#=GF CC   five-stranded antiparallel beta-sheets rotated away from each
#=GF CC   other by approx 25 degrees, and plays a similar role in meprin
#=GF CC   metalloproteinases [4].
#=GF SQ   4994
#=GS B0XHZ6_CULQU/137-308        AC B0XHZ6.1
#=GS W5K737_ASTMX/729-903        AC W5K737.1
#=GS U6LYV6_EIMMA/269-442        AC U6LYV6.1
#=GS H2PU04_PONAB/592-748        AC H2PU04.1
#=GS G1TAN6_RABIT/614-772        AC G1TAN6.1
#=GS B4E1Y9_HUMAN/26-169         AC B4E1Y9.1
#=GS W4Y5M9_STRPU/261-392        AC W4Y5M9.1
#=GS Q8CC97_MOUSE/377-534        AC Q8CC97.1
#=GS G1P9U5_MYOLU/133-292        AC G1P9U5.1
#=GS G1N654_MELGA/1-86           AC G1N654.2
#=GS M1SUQ3_9CNID/1-118          AC M1SUQ3.1
#=GS M3XTZ2_MUSPF/402-545        AC M3XTZ2.1
#=GS G3N437_GASAC/6-165          AC G3N437.1
#=GS E7FDQ2_DANRE/1-146          AC E7FDQ2.1
#=GS S9WT28_9CETA/4-133          AC S9WT28.1
#=GS W4ZI47_STRPU/123-289        AC W4ZI47.1
#=GS K7BNM1_PANTR/646-802        AC K7BNM1.1
#=GS MAMC2_MOUSE/44-169          AC Q8CG85.1
#=GS G1MUD6_MELGA/4-163          AC G1MUD6.2
#=GS T1KRE9_TETUR/1-182          AC T1KRE9.1
#=GS W4Z4K7_STRPU/1632-1791      AC W4Z4K7.1
#=GS Q9QX38_RAT/649-810          AC Q9QX38.1
#=GS B4I303_DROSE/132-305        AC B4I303.1
#=GS G1MQL0_MELGA/660-814        AC G1MQL0.1
#=GS C3XV81_BRAFL/27-185         AC C3XV81.1
#=GS T1KQ46_TETUR/32-181         AC T1KQ46.1
#=GS A7SGX2_NEMVE/1-43           AC A7SGX2.1
#=GS H2U2Q0_TAKRU/172-338        AC H2U2Q0.1
#=GS Q6V6S4_DROME/135-311        AC Q6V6S4.1
#=GS G3TY90_LOXAF/293-448        AC G3TY90.1
#=GS G3VX37_SARHA/986-1153       AC G3VX37.1
#=GS A9E0K7_9FLAO/938-1101       AC A9E0K7.1
#=GS M7B1N4_CHEMY/343-500        AC M7B1N4.1
#=GS Q68FP0_RAT/1-57             AC Q68FP0.1
#=GS F1LPJ1_RAT/27-184           AC F1LPJ1.2
#=GS H2MLD8_ORYLA/237-399        AC H2MLD8.1
#=GS A7S1N6_NEMVE/136-296        AC A7S1N6.1
#=GS W4XD81_STRPU/37-196         AC W4XD81.1
#=GS A1BVV1_DROMI/210-239        AC A1BVV1.1
#=GS A0A034VMN7_BACDO/331-494    AC A0A034VMN7.1
#=GS Q3ZTN3_SAISC/114-276        AC Q3ZTN3.1
#=GS A0A044RDI2_ONCVO/6-131      AC A0A044RDI2.1
#=GS H2QXC3_PANTR/342-498        AC H2QXC3.1
#=GS F6RPX8_ORNAN/557-710        AC F6RPX8.1
#=GS G3WQU6_SARHA/583-745        AC G3WQU6.1
#=GS F1MME1_BOVIN/35-193         AC F1MME1.2
#=GS MALR1_HUMAN/1-112           AC Q5VYJ5.3
#=GS B3RL76_TRIAD/47-120         AC B3RL76.1
#=GS H2TDC9_TAKRU/1-163          AC H2TDC9.1
#=GS Q8QZY7_MOUSE/646-802        AC Q8QZY7.1
#=GS H2T8U6_TAKRU/2-123          AC H2T8U6.1
#=GS A7RL30_NEMVE/3513-3672      AC A7RL30.1
#=GS A0A024NQZ9_BRUMA/3-69       AC A0A024NQZ9.1
#=GS F6SQA1_XENTR/967-1131       AC F6SQA1.1
#=GS W4YF92_STRPU/47-204         AC W4YF92.1
#=GS A7RL31_NEMVE/1312-1473      AC A7RL31.1
#=GS B7QGR2_IXOSC/1-86           AC B7QGR2.1
#=GS H3DNE1_TETNG/164-322        AC H3DNE1.1
#=GS H3CQ93_TETNG/344-501        AC H3CQ93.1
#=GS L8IHZ5_9CETA/42-169         AC L8IHZ5.1
#=GS D3Z499_MOUSE/746-911        AC D3Z499.1
#=GS V5H9L0_IXORI/1576-1737      AC V5H9L0.1
#=GS K7FZC6_PELSI/27-187         AC K7FZC6.1
#=GS V4C844_LOTGI/6541-6700      AC V4C844.1
#=GS C3Z758_BRAFL/82-239         AC C3Z758.1
#=GS L8H4E9_ACACA/63-222         AC L8H4E9.1
#=GS H2Y4X7_CIOSA/4-167          AC H2Y4X7.1
#=GS H2YIR2_CIOSA/208-376        AC H2YIR2.1
#=GS G5BEI2_HETGA/753-909        AC G5BEI2.1
#=GS MLRP2_ACRMI/4279-4438       AC B3EWZ6.1
#=GS V8P1U4_OPHHA/1-119          AC V8P1U4.1
#=GS G1SU80_RABIT/646-802        AC G1SU80.2
#=GS T1KD73_TETUR/199-352        AC T1KD73.1
#=GS E1FWA7_LOALO/7-167          AC E1FWA7.1
#=GS L9K1D8_TUPCH/238-401        AC L9K1D8.1
#=GS A2TTG8_9FLAO/49-206         AC A2TTG8.1
#=GS L5M451_MYODS/212-355        AC L5M451.1
#=GS K1RKI0_CRAGI/4728-4889      AC K1RKI0.1
#=GS W5LXN0_LEPOC/647-814        AC W5LXN0.1
#=GS A7S5N4_NEMVE/90-238         AC A7S5N4.1
#=GS W4XK90_STRPU/327-418        AC W4XK90.1
#=GS R7VBR3_CAPTE/262-420        AC R7VBR3.1
#=GS H0X7A1_OTOGA/1-123          AC H0X7A1.1
#=GS K1QWZ9_CRAGI/463-619        AC K1QWZ9.1
#=GS U3FS14_CALJA/753-918        AC U3FS14.1
#=GS W5N2W7_LEPOC/263-427        AC W5N2W7.1
#=GS M3YWE2_MUSPF/149-302        AC M3YWE2.1
#=GS Q58SF2_DROSI/136-312        AC Q58SF2.1
#=GS L8IHZ5_9CETA/342-498        AC L8IHZ5.1
#=GS B4DMY1_HUMAN/1-86           AC B4DMY1.1
#=GS W5NIB3_LEPOC/261-423        AC W5NIB3.1
#=GS A7RL30_NEMVE/3318-3479      AC A7RL30.1
#=GS G0NYY8_CAEBE/29-185         AC G0NYY8.1
#=GS L0CPC9_DROME/136-312        AC L0CPC9.1
#=GS W4YIX1_STRPU/1118-1275      AC W4YIX1.1
#=GS W4XHB5_STRPU/246-324        AC W4XHB5.1
#=GS U6DAY3_NEOVI/379-545        AC U6DAY3.1
#=GS D3YY20_MOUSE/498-653        AC D3YY20.1
#=GS W4Z4K7_STRPU/1129-1289      AC W4Z4K7.1
#=GS H0XFF1_OTOGA/807-963        AC H0XFF1.1
#=GS V4C844_LOTGI/2546-2596      AC V4C844.1
#=GS M0R8D4_RAT/441-580          AC M0R8D4.1
#=GS F1PEG4_CANFA/170-329        AC F1PEG4.2
#=GS E9GBN9_DAPPU/50-211         AC E9GBN9.1
#=GS B3DFP6_DANRE/636-796        AC B3DFP6.1
#=GS I3JHY5_ORENI/1-117          AC I3JHY5.1
#=GS G3SHG1_GORGO/269-433        AC G3SHG1.1
#=GS R7T5D8_CAPTE/597-749        AC R7T5D8.1
#=GS M0R592_RAT/304-460          AC M0R592.1
#=GS W5KHR4_ASTMX/1-76           AC W5KHR4.1
#=GS F7B522_ORNAN/329-470        AC F7B522.2
#=GS E1C0P4_CHICK/661-813        AC E1C0P4.2
#=GS K1RKI0_CRAGI/4388-4553      AC K1RKI0.1
#=GS V5HJW7_IXORI/1-86           AC V5HJW7.1
#=GS U3INX6_ANAPL/1-123          AC U3INX6.1
#=GS R5ETF8_9BACE/867-1019       AC R5ETF8.1
#=GS G5BEI2_HETGA/599-749        AC G5BEI2.1
#=GS W4YPG6_STRPU/171-250        AC W4YPG6.1
#=GS G5C302_HETGA/249-413        AC G5C302.1
#=GS A5I9F0_RAT/35-193           AC A5I9F0.1
#=GS Q6V6E4_DROSI/136-312        AC Q6V6E4.1
#=GS K1QMS6_CRAGI/205-363        AC K1QMS6.1
#=GS G1K9P9_ANOCA/404-548        AC G1K9P9.2
#=GS W4ZEL3_STRPU/1618-1777      AC W4ZEL3.1
#=GS H0Y4Q2_HUMAN/63-159         AC H0Y4Q2.2
#=GS F7GJQ2_CALJA/577-730        AC F7GJQ2.1
#=GS A7S956_NEMVE/1-97           AC A7S956.1
#=GS F1LMU6_RAT/976-1141         AC F1LMU6.1
#=GS B4KHE2_DROMO/148-325        AC B4KHE2.1
#=GS G1RB92_NOMLE/973-1138       AC G1RB92.1
#=GS G1N2R7_MELGA/344-485        AC G1N2R7.2
#=GS MLRP2_ACRMI/2441-2601       AC B3EWZ6.1
#=GS A7RL30_NEMVE/2990-3151      AC A7RL30.1
#=GS R1B798_EMIHU/559-710        AC R1B798.1
#=GS Q2EG55_MACNG/41-204         AC Q2EG55.1
#=GS C3ZER7_BRAFL/177-327        AC C3ZER7.1
#=GS K1Q6C7_CRAGI/799-986        AC K1Q6C7.1
#=GS M0R4V7_RAT/427-566          AC M0R4V7.1
#=GS A7SDB2_NEMVE/155-303        AC A7SDB2.1
#=GS B3S5U0_TRIAD/182-340        AC B3S5U0.1
#=GS G1MQL3_MELGA/69-230         AC G1MQL3.2
#=GS R1D749_EMIHU/758-887        AC R1D749.1
#=GS H2LIV8_ORYLA/652-819        AC H2LIV8.1
#=GS F6RAJ2_CALJA/830-882        AC F6RAJ2.1
#=GS E9H212_DAPPU/643-815        AC E9H212.1
#=GS W5PJ36_SHEEP/451-592        AC W5PJ36.1
#=GS H3B3Q2_LATCH/402-553        AC H3B3Q2.1
#=GS W5MY26_LEPOC/1-77           AC W5MY26.1
#=GS W5MY12_LEPOC/438-604        AC W5MY12.1
#=GS K7FS05_PELSI/283-440        AC K7FS05.1
#=GS U3JT91_FICAL/2-127          AC U3JT91.1
#=GS K1QGP8_CRAGI/1611-1775      AC K1QGP8.1
#=GS F1RW01_PIG/830-986          AC F1RW01.2
#=GS Q5ELX1_DROME/136-312        AC Q5ELX1.1
#=GS F7G9W1_MACMU/646-801        AC F7G9W1.1
#=GS F6RM13_MACMU/41-204         AC F6RM13.1
#=GS W4Z4K7_STRPU/4611-4771      AC W4Z4K7.1
#=GS R1D843_EMIHU/275-429        AC R1D843.1
#=GS U6MST2_9EIME/235-408        AC U6MST2.1
#=GS H2RL98_TAKRU/729-906        AC H2RL98.1
#=GS R1E4X9_EMIHU/461-607        AC R1E4X9.1
#=GS NPNT_MOUSE/422-561          AC Q91V88.1
#=GS A7SY78_NEMVE/95-251         AC A7SY78.1
#=GS G1RQA0_NOMLE/1-117          AC G1RQA0.1
#=GS H0XB99_OTOGA/26-185         AC H0XB99.1
#=GS G1N2S7_MELGA/396-535        AC G1N2S7.2
#=GS M3Y3H4_MUSPF/650-811        AC M3Y3H4.1
#=GS V5H9H1_IXORI/1384-1529      AC V5H9H1.1
#=GS V5GM05_IXORI/1996-2156      AC V5GM05.1
#=GS G1TGV7_RABIT/66-223         AC G1TGV7.2
#=GS Q5ELJ7_DROSI/132-308        AC Q5ELJ7.1
#=GS I3JFD3_ORENI/614-770        AC I3JFD3.1
#=GS G3WFX9_SARHA/1-120          AC G3WFX9.1
#=GS D2I2Z4_AILME/3-164          AC D2I2Z4.1
#=GS B1KFJ8_SHEWM/285-446        AC B1KFJ8.1
#=GS T1KZ18_TETUR/1076-1241      AC T1KZ18.1
#=GS E1BBK6_BOVIN/451-592        AC E1BBK6.2
#=GS W4XFG9_STRPU/4475-4633      AC W4XFG9.1
#=GS K1PQH8_CRAGI/173-313        AC K1PQH8.1
#=GS G1MQL3_MELGA/494-644        AC G1MQL3.2
#=GS Q4RWU3_TETNG/4-126          AC Q4RWU3.1
#=GS Q9N2Q3_DROME/143-316        AC Q9N2Q3.1
#=GS I3JU90_ORENI/33-188         AC I3JU90.1
#=GS W4Z4K7_STRPU/3244-3406      AC W4Z4K7.1
#=GS W4Y830_STRPU/47-201         AC W4Y830.1
#=GS H2MJJ4_ORYLA/749-923        AC H2MJJ4.1
#=GS I3JL12_ORENI/26-186         AC I3JL12.1
#=GS K1QBN8_CRAGI/596-751        AC K1QBN8.1
#=GS F7A3J7_XENTR/391-535        AC F7A3J7.1
#=GS U3JMJ0_FICAL/647-809        AC U3JMJ0.1
#=GS W5LIB1_ASTMX/471-613        AC W5LIB1.1
#=GS F7I809_CALJA/8-129          AC F7I809.1
#=GS D2HWA9_AILME/125-298        AC D2HWA9.1
#=GS A7RL31_NEMVE/4468-4636      AC A7RL31.1
#=GS G3SF75_GORGO/265-428        AC G3SF75.1
#=GS H2PSC4_PONAB/170-329        AC H2PSC4.1
#=GS B3DKP9_DANRE/264-425        AC B3DKP9.1
#=GS W4YEA6_STRPU/633-793        AC W4YEA6.1
#=GS H2N2M5_ORYLA/1-121          AC H2N2M5.1
#=GS H9GGH1_ANOCA/1-110          AC H9GGH1.1
#=GS K1RDC6_CRAGI/21-139         AC K1RDC6.1
#=GS V5HEW6_IXORI/80-232         AC V5HEW6.1
#=GS T1KZ18_TETUR/2228-2396      AC T1KZ18.1
#=GS C3XSG2_BRAFL/40-214         AC C3XSG2.1
#=GS E9PY95_MOUSE/754-919        AC E9PY95.1
#=GS R7TIH4_CAPTE/255-409        AC R7TIH4.1
#=GS A7RL30_NEMVE/4030-4190      AC A7RL30.1
#=GS H2Q1T2_PANTR/650-811        AC H2Q1T2.1
#=GS G3NN30_GASAC/628-666        AC G3NN30.1
#=GS C3XSH5_BRAFL/150-308        AC C3XSH5.1
#=GS Q2EG71_PONPY/198-361        AC Q2EG71.1
#=GS W5NBX4_LEPOC/250-410        AC W5NBX4.1
#=GS F7EHU3_MACMU/348-505        AC F7EHU3.1
#=GS C3ZGX1_BRAFL/185-357        AC C3ZGX1.1
#=GS G1NPD2_MELGA/384-528        AC G1NPD2.1
#=GS L5LU46_MYODS/22-185         AC L5LU46.1
#=GS T1KZ18_TETUR/1461-1626      AC T1KZ18.1
#=GS B3S5U1_TRIAD/1070-1228      AC B3S5U1.1
#=GS G1KFQ6_ANOCA/643-803        AC G1KFQ6.2
#=GS W5LII6_ASTMX/645-812        AC W5LII6.1
#=GS NRP2_HUMAN/646-802          AC O60462.2
#=GS A8CF63_SEPLE/65-221         AC A8CF63.1
#=GS F6RJ58_MACMU/2-159          AC F6RJ58.1
#=GS C3YSW1_BRAFL/27-191         AC C3YSW1.1
#=GS E2C598_HARSA/524-701        AC E2C598.1
#=GS G1K8Z1_ANOCA/173-332        AC G1K8Z1.2
#=GS F1NSH7_CHICK/1-148          AC F1NSH7.2
#=GS H0YSL2_TAEGU/16-169         AC H0YSL2.1
#=GS D2I261_AILME/1-163          AC D2I261.1
#=GS B4QI13_DROSI/288-450        AC B4QI13.1
#=GS G3HAF0_CRIGR/17-179         AC G3HAF0.1
#=GS G3U6T5_LOXAF/210-383        AC G3U6T5.1
#=GS H2YNQ8_CIOSA/674-841        AC H2YNQ8.1
#=GS D2H770_AILME/3-160          AC D2H770.1
#=GS W4XM59_STRPU/94-255         AC W4XM59.1
#=GS Q5ELL2_DROSI/132-308        AC Q5ELL2.1
#=GS R0K979_ANAPL/55-215         AC R0K979.1
#=GS R7TWE8_CAPTE/205-360        AC R7TWE8.1
#=GS Q4SXP5_TETNG/422-590        AC Q4SXP5.1
#=GS I3K5C8_ORENI/635-782        AC I3K5C8.1
#=GS Q5ELR9_DROME/136-312        AC Q5ELR9.1
#=GS L5JZ81_PTEAL/751-924        AC L5JZ81.1
#=GS G3NIT5_GASAC/652-809        AC G3NIT5.1
#=GS F6YI21_XENTR/27-184         AC F6YI21.1
#=GS Q4T686_TETNG/238-403        AC Q4T686.1
#=GS G1RZS6_NOMLE/95-251         AC G1RZS6.1
#=GS W4ZI47_STRPU/301-466        AC W4ZI47.1
#=GS M3YDQ3_MUSPF/43-169         AC M3YDQ3.1
#=GS F7BX47_HORSE/1-123          AC F7BX47.1
#=GS E5S113_TRISP/323-486        AC E5S113.1
#=GS A9UUN4_MONBE/476-624        AC A9UUN4.1
#=GS G1KIT6_ANOCA/42-91          AC G1KIT6.1
#=GS Q9U3K4_CAEEL/103-265        AC Q9U3K4.1
#=GS F6YK07_ORNAN/646-802        AC F6YK07.1
#=GS W5N4K0_LEPOC/421-563        AC W5N4K0.1
#=GS F7GJQ2_CALJA/271-425        AC F7GJQ2.1
#=GS B0WFS9_CULQU/165-290        AC B0WFS9.1
#=GS K1QLQ1_CRAGI/1406-1568      AC K1QLQ1.1
#=GS H2TEX5_TAKRU/653-808        AC H2TEX5.1
#=GS R9W7X6_RAT/608-770          AC R9W7X6.1
#=GS MDGA2_MACFA/243-416         AC Q9GMT4.2
#=GS E3MVV9_CAERE/30-187         AC E3MVV9.1
#=GS A3J0V8_9FLAO/875-1031       AC A3J0V8.1
#=GS M4ASP3_XIPMA/747-921        AC M4ASP3.1
#=GS A0A023BZV4_9FLAO/594-754    AC A0A023BZV4.1
#=GS Q58SF8_DROSI/136-312        AC Q58SF8.1
#=GS K1QLQ1_CRAGI/720-882        AC K1QLQ1.1
#=GS C3Z3A6_BRAFL/4-163          AC C3Z3A6.1
#=GS V9IAA1_APICE/270-446        AC V9IAA1.1
#=GS H2T8U7_TAKRU/1-120          AC H2T8U7.1
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#=GS H0YW58_TAEGU/245-396        AC H0YW58.1
#=GS U3INX6_ANAPL/124-283        AC U3INX6.1
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#=GS K7GIE9_PELSI/222-386        AC K7GIE9.1
#=GS C3XVF3_BRAFL/1-142          AC C3XVF3.1
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W5K737_ASTMX/729-903                   .........................................................................CGF.......EDV......RIC...G...F...S......Q.......D....RS..............DVF......DWTR...QNHL.SQnp...........krSVN...T...G.....P.D.T.DR.SGTKE.......................-GYYM..Y....IE..TSRP......rQRGD........................................KA.R..L..L.SP..LYn.vT--Aargpa.............gsgrvPHC...IS..FFY.HM.......N.....GKHI......................GT....L...N...VLLRVK...............................sIATVDSV....................V..W...SR......S....G....S.Q.G.............PS..W..Q..K..A..S..LM.....VM.......P-.........SG....P............F........Q..V..............VF..E.......G....I.R..GD................GFE....GD..IA.I.DDVSVS.KG....KCT-q..........................................
U6LYV6_EIMMA/269-442                   .........................................................................CDF.......EEG......-MC...GlmsF...V......V.......D....PR..............LSL......EWRR...HSGA.TE...............TAG...T...G.....P.S.F.DH.TYGRRq....................rrRGHYL..Y....MD..SPGY.......MLGE........................................SA.A..L..L.AA..AQ..iYPKG.......................LYC...LR..LWY.HM.......Y.....GEDV......................NS....L...R...VYMRYLegd..........................aetLGDWGKP....................Y..L...LR......V....G....D.H.G.............DD..W..L..E..A..G..FE.....FT.......SD........gHT....A............Q........Q..L..............VI..E.......A....L.A..GF................GEK....GD..IA.I.DDLRIV.SG....KCP-e..........................................
H2PU04_PONAB/592-748                   .........................................................................CSF.......EDS......-DC...G...F...S......P.......G....GQ..............--G......LWRR...QASA.SG...............HAA...W...G.....P.P.T.DH.TTETA.......................QGHYM..V....VD..TSPDa.....lPRGQ........................................TA.S..L..T.SK..EH..rPLAQ.......................PAC...LT..FWY.HG.......S.....LRSP......................GT....L...R...VYLEER................................---GRHQ....................V..L...NL......S....A....H.G.G.............LA..W..R..L..G..S..VD.....VQ.......A-.........ER....A............W........R..V..............VF..E.......A....V.A..TD................VAH....SY..VA.L.DDLLLQ.DG....PCP-q..........................................
G1TAN6_RABIT/614-772                   .........................................................................CDF.......EFD......-LC...A...W...E......Q.......E....QD..............EDF......DWNL...KASS.IL...............ATG...T...E.....P.V.A.DH.TLGNS.......................SGHYI..F....IK..SLFP......qQPMR........................................AA.R..I..S.SP..VI...SKRS.......................KNC..kII..FHY.HM.......Y.....GNGI......................GA....L...S...LIQVSV................................-SNQTKV....................L..L...NL......T....A....E.Q.G.............NF..W..K..R..E..E..LP.....LF.......G-.........DE....D............F........Q..L..............KF..E.......G....R.V..GK................GYH....GD..IA.L.DDIVLT.-E....NC--ls.........................................
B4E1Y9_HUMAN/26-169                    ...................................................cafeestcgfdsvlaslpwiln---.......---......---...-...-...-......-.......-....--..............---......----...----.--...............---...-...-.....-.-.-.--.----E.......................EGHYI..Y....VD..TSFG.......KQGE........................................KA.V..L..L.SP..DL...QAEE.......................WSC...LR..LVY.QI.......T.....TSSEsl.................sdpSQ....L...N...LYMRFE................................DESFDRL....................L..W...-S......A....K....E.P.S.............DS..W..L..I..A..S..LD.....LQ.......NS.........SK....K............F........K..I..............LI..E.......G....V.L..GQ................GNT....AS..IA.L.FEIKMT.TG....YC--ie.........................................
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A0A023C0R7_9FLAO/1125-1281             ........................................................................g--F.......EAG......-MG...G...W...T......Q.......G....AG..............DDF......DWTR...QSGG.TR...............SRN...T...G.....P.S.G.AQ.EGSN-.......................---YI..Y....VE..TSAP......nNPNK........................................RT.I..L..N.SP..CF...DLNGv.....................nSPS...FT..FRY.HM.......L.....GNAV......................GE....L...K...LEISND................................NGANWVS....................I..W...SK......T....G....T.Q.G.............NA..W..N..N..A..N..VD.....LN.......AY........iGR....S............I........K..M..............RF..I.......G....T.S..GS................SWQ....GD..MA.V.DNISLT.T-....----sna........................................
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H2MZF7_ORYLA/1-119                     .........................................................................---.......---......---...-...-...-......-.......-....--..............---......----...----.--...............---...-...-.....-.-.-.--.-----.......................--SFL..F....VN..TSSR.......YSGQ........................................RA.Q..L..L.LP..PL...KEND.......................THC...LS..FFF.YQ.......A.....GGREgi..................ppAT....L...N...VYVKEN................................NNALGVP....................V..F...NS......S....G....P.A.Y.............HI..W..K..E..V..E..LA.....VS.......IF........wPN....Q............Y........Q..L..............VL..E.......A....I.S..-T................GQK....GL..LA.I.KDISLQ.GH....QCM-r..........................................
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