GenomeNet

Database: Pfam
Entry: MBD
LinkDB: MBD
Original site: MBD 
#=GF ID   MBD
#=GF AC   PF01429.16
#=GF DE   Methyl-CpG binding domain
#=GF AU   Bateman A
#=GF SE   Bateman A
#=GF GA   20.70 20.70;
#=GF TC   20.70 20.80;
#=GF NC   20.60 20.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   8177735
#=GF RT   Dissection of the methyl-CpG binding domain from the chromosomal
#=GF RT   protein MeCP2. 
#=GF RA   Nan X, Meehan RR, Bird A; 
#=GF RL   Nucleic Acids Res 1993;21:4886-4892.
#=GF RN   [2]
#=GF RM   10050851
#=GF RT   A mammalian protein with specific demethylase activity for mCpG
#=GF RT   DNA. 
#=GF RA   Bhattacharya SK, Ramchandani S, Cervoni N, Szyf M; 
#=GF RL   Nature 1999;397:579-583.
#=GF DR   INTERPRO; IPR001739;
#=GF DR   SCOP; 1qk9; fa;
#=GF DR   HOMSTRAD; MBD;
#=GF CC   The Methyl-CpG binding domain (MBD) binds to DNA that contains
#=GF CC   one or more symmetrically methylated CpGs [1].  DNA methylation
#=GF CC   in animals is associated with alterations in chromatin structure
#=GF CC   and silencing of gene expression. MBD has negligible
#=GF CC   non-specific affinity for DNA. In vitro foot-printing with MeCP2
#=GF CC   showed the MBD can protect a 12 nucleotide region surrounding a
#=GF CC   methyl CpG pair [1]. MBDs are found in several Methyl-CpG
#=GF CC   binding proteins and also DNA demethylase [2].
#=GF SQ   1450
#=GS W5FAJ3_WHEAT/143-225       AC W5FAJ3.1
#=GS G3HRN1_CRIGR/515-589       AC G3HRN1.1
#=GS W4ZR58_WHEAT/80-157        AC W4ZR58.1
#=GS C1EC12_MICSR/488-559       AC C1EC12.1
#=GS B4L8F7_DROMO/259-323       AC B4L8F7.1
#=GS Q7Q3S9_ANOGA/877-952       AC Q7Q3S9.4
#=GS A0A072TV37_MEDTR/79-150    AC A0A072TV37.1
#=GS G5C2R7_HETGA/112-183       AC G5C2R7.1
#=GS G3VAD7_SARHA/475-549       AC G3VAD7.1
#=GS M0TDS1_MUSAM/126-223       AC M0TDS1.1
#=GS J3MHD1_ORYBR/218-324       AC J3MHD1.1
#=GS T1IRX7_STRMM/188-262       AC T1IRX7.1
#=GS A0A0D9RZQ1_CHLSB/1-88      AC A0A0D9RZQ1.1
#=GS K4BLH0_SOLLC/2-73          AC K4BLH0.1
#=GS F7FBN3_MACMU/1-91          AC F7FBN3.1
#=GS W5HS75_WHEAT/26-93         AC W5HS75.1
#=GS B8BN22_ORYSI/25-116        AC B8BN22.1
#=GS W5F5U2_WHEAT/34-88         AC W5F5U2.1
#=GS A0A087X1U4_HUMAN/87-158    AC A0A087X1U4.1
#=GS I1I7N9_BRADI/35-99         AC I1I7N9.1
#=GS A0A072UGI6_MEDTR/243-323   AC A0A072UGI6.1
#=GS W5MFY6_LEPOC/739-793       AC W5MFY6.1
#=GS T1IHM2_STRMM/80-256        AC T1IHM2.1
#=GS G3VYZ6_SARHA/151-222       AC G3VYZ6.1
#=GS H3D4X9_TETNG/549-623       AC H3D4X9.1
#=GS I1J1S5_BRADI/473-567       AC I1J1S5.1
#=GS W5LF89_ASTMX/1-146         AC W5LF89.1
#=GS T1IHD7_STRMM/197-282       AC T1IHD7.1
#=GS H0UWR2_CAVPO/1-88          AC H0UWR2.1
#=GS I1GWQ7_BRADI/157-230       AC I1GWQ7.1
#=GS M0S7H8_MUSAM/24-99         AC M0S7H8.1
#=GS G3RLB8_GORGO/27-114        AC G3RLB8.1
#=GS Q9VGA4_DROME/445-519       AC Q9VGA4.2
#=GS F7DFU8_MACMU/147-217       AC F7DFU8.1
#=GS U4UJB6_DENPD/433-508       AC U4UJB6.1
#=GS J9KGG6_ACYPI/342-414       AC J9KGG6.2
#=GS T1JD93_STRMM/548-615       AC T1JD93.1
#=GS A0A0D3ADA6_BRAOL/136-203   AC A0A0D3ADA6.1
#=GS B3LZL0_DROAN/453-527       AC B3LZL0.1
#=GS E1BNJ5_BOVIN/738-812       AC E1BNJ5.2
#=GS K4DA48_SOLLC/10-97         AC K4DA48.1
#=GS B4JTJ6_DROGR/451-525       AC B4JTJ6.1
#=GS H9L3I9_CHICK/573-647       AC H9L3I9.2
#=GS G1MQP3_MELGA/606-680       AC G1MQP3.2
#=GS G5B9Z0_HETGA/153-226       AC G5B9Z0.1
#=GS I1ELE4_AMPQE/1-52          AC I1ELE4.1
#=GS A0A024MZP5_BRUMA/52-149    AC A0A024MZP5.1
#=GS M0XR91_HORVD/308-374       AC M0XR91.1
#=GS F8VU39_HUMAN/544-618       AC F8VU39.1
#=GS W5MFZ1_LEPOC/50-101        AC W5MFZ1.1
#=GS C5YK76_SORBI/92-162        AC C5YK76.1
#=GS F6WF74_MONDO/2-72          AC F6WF74.2
#=GS A0A022PT40_ERYGU/144-232   AC A0A022PT40.1
#=GS I1PJA0_ORYGL/101-170       AC I1PJA0.1
#=GS A0A091DB01_FUKDA/79-153    AC A0A091DB01.1
#=GS K7GM47_PIG/91-162          AC K7GM47.1
#=GS A0A022QMM0_ERYGU/9-81      AC A0A022QMM0.1
#=GS L5M3A8_MYODS/6-78          AC L5M3A8.1
#=GS H3CHQ4_TETNG/26-96         AC H3CHQ4.1
#=GS H2STH8_TAKRU/106-176       AC H2STH8.1
#=GS A0A088APQ1_APIME/614-682   AC A0A088APQ1.1
#=GS A0A093BHY2_CHAPE/1-36      AC A0A093BHY2.1
#=GS D7MT30_ARALL/111-174       AC D7MT30.1
#=GS M3XQY1_MUSPF/523-597       AC M3XQY1.1
#=GS W5B5Y9_WHEAT/95-159        AC W5B5Y9.1
#=GS W5FKE4_WHEAT/2-55          AC W5FKE4.1
#=GS V3Z1H3_LOTGI/204-277       AC V3Z1H3.1
#=GS K4DB14_SOLLC/34-96         AC K4DB14.1
#=GS A8HVX2_CHLRE/239-313       AC A8HVX2.1
#=GS G7KM19_MEDTR/12-76         AC G7KM19.1
#=GS M0V3L9_HORVD/145-223       AC M0V3L9.1
#=GS H2P7L9_PONAB/648-722       AC H2P7L9.1
#=GS U3JKS5_FICAL/674-748       AC U3JKS5.1
#=GS W4WWZ5_ATTCE/505-581       AC W4WWZ5.1
#=GS H0X2F3_OTOGA/593-667       AC H0X2F3.1
#=GS T1IHM6_STRMM/453-548       AC T1IHM6.1
#=GS Q94IR1_MAIZE/84-154        AC Q94IR1.1
#=GS T1IU14_STRMM/165-236       AC T1IU14.1
#=GS K4CP67_SOLLC/109-226       AC K4CP67.1
#=GS F7GUP3_MACMU/740-814       AC F7GUP3.1
#=GS G7KND5_MEDTR/61-132        AC G7KND5.2
#=GS H2LH77_ORYLA/688-742       AC H2LH77.1
#=GS T1III7_STRMM/1-65          AC T1III7.1
#=GS A0A091CX08_FUKDA/693-745   AC A0A091CX08.1
#=GS T1IHB9_STRMM/85-200        AC T1IHB9.1
#=GS A0A072UCD8_MEDTR/162-257   AC A0A072UCD8.1
#=GS T1IRD0_STRMM/434-522       AC T1IRD0.1
#=GS T1IGX5_STRMM/432-504       AC T1IGX5.1
#=GS T1JMF5_STRMM/3-72          AC T1JMF5.1
#=GS F6S9T0_XENTR/172-245       AC F6S9T0.1
#=GS E2R214_CANFA/4-91          AC E2R214.2
#=GS A0A096LY04_POEFO/870-944   AC A0A096LY04.1
#=GS H2V451_TAKRU/685-740       AC H2V451.1
#=GS T1IHC9_STRMM/113-193       AC T1IHC9.1
#=GS M0R6H5_RAT/126-198         AC M0R6H5.1
#=GS H2S6E5_TAKRU/146-235       AC H2S6E5.1
#=GS E2RP61_CANFA/739-813       AC E2RP61.2
#=GS A0A0D3FTI2_9ORYZ/238-302   AC A0A0D3FTI2.1
#=GS T1IQ26_STRMM/77-147        AC T1IQ26.1
#=GS W5JPC4_ANODA/457-528       AC W5JPC4.1
#=GS B4M4B3_DROVI/9-80          AC B4M4B3.1
#=GS F4WX29_ACREC/270-340       AC F4WX29.1
#=GS X6RBL6_HUMAN/146-216       AC X6RBL6.1
#=GS A0A087WXF0_HUMAN/91-162    AC A0A087WXF0.1
#=GS H2NHQ9_PONAB/544-618       AC H2NHQ9.2
#=GS M7YS85_TRIUA/178-268       AC M7YS85.1
#=GS F0YN94_AURAN/328-414       AC F0YN94.1
#=GS B9IJM9_POPTR/221-316       AC B9IJM9.2
#=GS A0A0G2JWK2_RAT/91-162      AC A0A0G2JWK2.1
#=GS F6ZF04_MONDO/1-72          AC F6ZF04.1
#=GS Q6YTR7_ORYSJ/193-255       AC Q6YTR7.1
#=GS K4D0F5_SOLLC/80-147        AC K4D0F5.1
#=GS R1CEH0_EMIHU/328-395       AC R1CEH0.1
#=GS G3HVL7_CRIGR/68-141        AC G3HVL7.1
#=GS H9GEA0_ANOCA/3-74          AC H9GEA0.2
#=GS K4CCB0_SOLLC/78-153        AC K4CCB0.1
#=GS M4EEJ5_BRARP/129-198       AC M4EEJ5.1
#=GS C5YIJ8_SORBI/259-334       AC C5YIJ8.1
#=GS T1J9M3_STRMM/61-151        AC T1J9M3.1
#=GS C5WUA6_SORBI/51-113        AC C5WUA6.1
#=GS F7FHB9_MACMU/1-72          AC F7FHB9.1
#=GS A0A022PT40_ERYGU/34-102    AC A0A022PT40.1
#=GS B4GIE1_DROPE/872-940       AC B4GIE1.1
#=GS H2M5X2_ORYLA/1-66          AC H2M5X2.1
#=GS T1IGT7_STRMM/343-405       AC T1IGT7.1
#=GS I3MGY7_SPETR/16-86         AC I3MGY7.1
#=GS I3KK71_ORENI/516-590       AC I3KK71.1
#=GS B7PPM4_IXOSC/541-608       AC B7PPM4.1
#=GS M4CR52_BRARP/89-163        AC M4CR52.1
#=GS A2XRA4_ORYSI/115-182       AC A2XRA4.1
#=GS A0A096LSP3_POEFO/80-174    AC A0A096LSP3.1
#=GS F1P989_CANFA/554-628       AC F1P989.2
#=GS G3W0W0_SARHA/91-162        AC G3W0W0.1
#=GS F6RU98_HORSE/755-829       AC F6RU98.1
#=GS V4NEN8_EUTSA/155-229       AC V4NEN8.1
#=GS SETB2_HUMAN/160-232        AC Q96T68.2
#=GS A9TNH5_PHYPA/133-207       AC A9TNH5.1
#=GS G3PR57_GASAC/535-609       AC G3PR57.1
#=GS Q94IQ6_MAIZE/139-221       AC Q94IQ6.1
#=GS T1IKB0_STRMM/168-236       AC T1IKB0.1
#=GS H0Z2Q1_TAEGU/513-587       AC H0Z2Q1.1
#=GS F7IKH9_CALJA/1-89          AC F7IKH9.1
#=GS T1IN31_STRMM/118-227       AC T1IN31.1
#=GS H2L6G4_ORYLA/149-210       AC H2L6G4.1
#=GS L5K5I1_PTEAL/596-670       AC L5K5I1.1
#=GS A0A096LWV0_POEFO/652-726   AC A0A096LWV0.1
#=GS F1QDB7_DANRE/248-318       AC F1QDB7.1
#=GS M4FH43_BRARP/269-341       AC M4FH43.1
#=GS K0SQF4_THAOC/49-112        AC K0SQF4.1
#=GS T1JZ06_TETUR/575-650       AC T1JZ06.1
#=GS A0A0D3ECW4_BRAOL/276-347   AC A0A0D3ECW4.1
#=GS G3RIW1_GORGO/160-232       AC G3RIW1.1
#=GS M1CB59_SOLTU/10-134        AC M1CB59.1
#=GS E0VSB9_PEDHC/589-658       AC E0VSB9.1
#=GS A0A087XP15_POEFO/128-251   AC A0A087XP15.2
#=GS H2TLE5_TAKRU/1-65          AC H2TLE5.1
#=GS W5A4P8_WHEAT/80-157        AC W5A4P8.1
#=GS B9IMX8_POPTR/7-64          AC B9IMX8.1
#=GS A8DYA3_DROME/948-1024      AC A8DYA3.1
#=GS E9GG97_DAPPU/541-616       AC E9GG97.1
#=GS E9HES9_DAPPU/235-304       AC E9HES9.1
#=GS T1IYR1_STRMM/493-562       AC T1IYR1.1
#=GS A0A087YDD1_POEFO/769-826   AC A0A087YDD1.2
#=GS T1IY94_STRMM/664-735       AC T1IY94.1
#=GS A0A022RHK1_ERYGU/22-117    AC A0A022RHK1.1
#=GS B8C5Q4_THAPS/825-933       AC B8C5Q4.1
#=GS D7ME09_ARALL/84-157        AC D7ME09.1
#=GS Q6AVA9_ORYSJ/61-131        AC Q6AVA9.1
#=GS T1IJT7_STRMM/181-262       AC T1IJT7.1
#=GS M4EYC2_BRARP/25-142        AC M4EYC2.1
#=GS A0A096M481_POEFO/16-90     AC A0A096M481.1
#=GS H9J1M6_BOMMO/690-836       AC H9J1M6.1
#=GS A8HVR2_CHLRE/57-131        AC A8HVR2.1
#=GS Q7XSE1_ORYSJ/89-159        AC Q7XSE1.2
#=GS G1T430_RABIT/599-673       AC G1T430.2
#=GS A0A0D3A8U3_BRAOL/25-144    AC A0A0D3A8U3.1
#=GS F6ZDA3_XENTR/1-92          AC F6ZDA3.1
#=GS J9P7P5_CANFA/596-670       AC J9P7P5.1
#=GS G3S799_GORGO/160-232       AC G3S799.1
#=GS E7F7L1_DANRE/150-213       AC E7F7L1.1
#=GS Q0ILV0_ORYSJ/25-109        AC Q0ILV0.1
#=GS A0A0D3FTI3_9ORYZ/238-302   AC A0A0D3FTI3.1
#=GS M7ZYA9_TRIUA/143-241       AC M7ZYA9.1
#=GS G7IPJ6_MEDTR/213-279       AC G7IPJ6.2
#=GS G3N2R6_BOVIN/94-165        AC G3N2R6.1
#=GS T1JKI7_STRMM/93-162        AC T1JKI7.1
#=GS Q94IQ8_MAIZE/1-83          AC Q94IQ8.1
#=GS H2S415_TAKRU/523-597       AC H2S415.1
#=GS J0XLD9_LOALO/335-409       AC J0XLD9.1
#=GS Q295J5_DROPS/9-99          AC Q295J5.2
#=GS A0A022QUJ3_ERYGU/54-159    AC A0A022QUJ3.1
#=GS F4X6H6_ACREC/507-583       AC F4X6H6.1
#=GS L5KVR4_PTEAL/1171-1245     AC L5KVR4.1
#=GS V4M6P3_EUTSA/258-357       AC V4M6P3.1
#=GS Q6ZJ98_ORYSJ/334-409       AC Q6ZJ98.1
#=GS M1DQF9_SOLTU/81-159        AC M1DQF9.1
#=GS M0X5E3_HORVD/35-93         AC M0X5E3.1
#=GS G1PG25_MYOLU/620-694       AC G1PG25.1
#=GS G1SQA2_RABIT/511-585       AC G1SQA2.1
#=GS J9P2D6_CANFA/91-162        AC J9P2D6.1
#=GS A0A072U5A2_MEDTR/176-318   AC A0A072U5A2.1
#=GS I1JWB8_SOYBN/12-85         AC I1JWB8.1
#=GS T1JCQ3_STRMM/226-305       AC T1JCQ3.1
#=GS K7EG33_ORNAN/1-44          AC K7EG33.1
#=GS SETB2_DANRE/150-213        AC Q06ZW3.2
#=GS H2V457_TAKRU/5-78          AC H2V457.1
#=GS A0A096M748_POEFO/2-77      AC A0A096M748.1
#=GS F4WSF5_ACREC/547-623       AC F4WSF5.1
#=GS A9TBW6_PHYPA/643-719       AC A9TBW6.1
#=GS B9RUU8_RICCO/275-371       AC B9RUU8.1
#=GS MET2_CAEEL/834-910         AC P34544.5
#=GS F6HHA3_VITVI/7-80          AC F6HHA3.1
#=GS U4U2N3_DENPD/234-300       AC U4U2N3.1
#=GS B5DYI5_DROPS/435-509       AC B5DYI5.1
#=GS F1LWH6_RAT/90-161          AC F1LWH6.1
#=GS H2ZZ78_LATCH/1-110         AC H2ZZ78.1
#=GS M4CR52_BRARP/155-243       AC M4CR52.1
#=GS H2UKE2_TAKRU/22-96         AC H2UKE2.1
#=GS K4CP67_SOLLC/1092-1226     AC K4CP67.1
#=GS A0A087Y1P6_POEFO/544-618   AC A0A087Y1P6.1
#=GS W5QI91_SHEEP/595-669       AC W5QI91.1
#=GS I3JR24_ORENI/172-236       AC I3JR24.1
#=GS A8XT55_CAEBR/789-865       AC A8XT55.2
#=GS T1IHH5_STRMM/90-160        AC T1IHH5.1
#=GS G3HQI6_CRIGR/13-110        AC G3HQI6.1
#=GS F4WGP5_ACREC/616-683       AC F4WGP5.1
#=GS Q2HU61_MEDTR/91-190        AC Q2HU61.2
#=GS C1MXF1_MICPC/48-133        AC C1MXF1.1
#=GS T1IM20_STRMM/63-136        AC T1IM20.1
#=GS A0A0D3FSV4_9ORYZ/34-96     AC A0A0D3FSV4.1
#=GS M3WBU8_FELCA/593-667       AC M3WBU8.1
#=GS V4L2K9_EUTSA/109-183       AC V4L2K9.1
#=GS H0V8P5_CAVPO/35-105        AC H0V8P5.1
#=GS B7Q0K4_IXOSC/10-80         AC B7Q0K4.1
#=GS T1ITV8_STRMM/431-502       AC T1ITV8.1
#=GS B4H2T3_DROPE/26-90         AC B4H2T3.1
#=GS A0A090M6R2_OSTTA/879-972   AC A0A090M6R2.1
#=GS I1I1X1_BRADI/243-312       AC I1I1X1.1
#=GS W5LC65_ASTMX/94-163        AC W5LC65.1
#=GS K3YIV8_SETIT/144-222       AC K3YIV8.1
#=GS Q94IQ7_MAIZE/135-217       AC Q94IQ7.1
#=GS A2Y4J4_ORYSI/160-245       AC A2Y4J4.1
#=GS K3YIX3_SETIT/144-227       AC K3YIX3.1
#=GS M7ZYV8_TRIUA/9-79          AC M7ZYV8.1
#=GS G3U3C2_LOXAF/4-78          AC G3U3C2.1
#=GS MECP2_RAT/91-162           AC Q00566.1
#=GS I1PJA2_ORYGL/52-123        AC I1PJA2.1
#=GS W1NIZ6_AMBTC/102-179       AC W1NIZ6.1
#=GS H2SUB3_TAKRU/1-93          AC H2SUB3.1
#=GS F6YYF6_HORSE/601-675       AC F6YYF6.1
#=GS F7IKD3_CALJA/1-89          AC F7IKD3.1
#=GS W1NIZ6_AMBTC/451-537       AC W1NIZ6.1
#=GS T1JC32_STRMM/168-242       AC T1JC32.1
#=GS Q2HU61_MEDTR/28-89         AC Q2HU61.2
#=GS I3J5G7_ORENI/772-827       AC I3J5G7.1
#=GS T1JBU3_STRMM/106-204       AC T1JBU3.1
#=GS F2DYW0_HORVD/80-157        AC F2DYW0.1
#=GS Q2KIY8_BOVIN/1-98          AC Q2KIY8.1
#=GS F6T588_XENTR/722-780       AC F6T588.1
#=GS A0A096Q5T1_MAIZE/139-219   AC A0A096Q5T1.1
#=GS F6ZIY9_MONDO/1-72          AC F6ZIY9.1
#=GS G3WHI1_SARHA/591-665       AC G3WHI1.1
#=GS I1PJA0_ORYGL/33-97         AC I1PJA0.1
#=GS D7MT30_ARALL/174-263       AC D7MT30.1
#=GS K0TQ33_THAOC/936-1024      AC K0TQ33.1
#=GS G0ME01_CAEBE/828-904       AC G0ME01.1
#=GS T1IKT3_STRMM/137-224       AC T1IKT3.1
#=GS T1IZ53_STRMM/198-270       AC T1IZ53.1
#=GS M3XN34_MUSPF/738-812       AC M3XN34.1
#=GS G1P2A0_MYOLU/148-220       AC G1P2A0.1
#=GS T1IH74_STRMM/198-270       AC T1IH74.1
#=GS Q17D97_AEDAE/371-440       AC Q17D97.1
#=GS Q66HB8_RAT/1-86            AC Q66HB8.1
#=GS A0A087XLG6_POEFO/138-223   AC A0A087XLG6.1
#=GS K1QBB3_CRAGI/183-253       AC K1QBB3.1
#=GS T1IRY1_STRMM/71-141        AC T1IRY1.1
#=GS Q01BC5_OSTTA/28-101        AC Q01BC5.1
#=GS A0A022QH41_ERYGU/167-239   AC A0A022QH41.1
#=GS B4QBM5_DROSI/948-1024      AC B4QBM5.1
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W5FAJ3_WHEAT/143-225                  ......................................................................................kpniaqp-----------.P..A..GW.ERQIR..I....R...G..E...G.G.T-......................................................KFA.DVYYT.S.............................................................P...TA.R..K.LRSL..VEVDRY...LQE.NPEy.........................................................................................................................gAQG..V..TL..A..QFSFQ-------iprplrqnyvkkrpkn..........................................................................................
G3HRN1_CRIGR/515-589                  ...........................................................................................ia--TPEEVRLPL.Q..H..GW.RREVR..I....K...K..G...G.-.HR......................................................WQG.ETWYY.G.............................................................P...CG.K..R.MKQF..PEVIKY...LSR.NV-...........................................................................................................................VHS..V..RR..E..HFSFSPRMPV--gd........................................................................................................
W4ZR58_WHEAT/80-157                   .................................................................sriwvidkpnipkpppkterlvimrgdl-----------.-..-..--.-----..-....-...-..-...-.-.--......................................................SKM.DIYYV.L.............................................................P...NG.K..R.ARGI..GDVQKF...LDT.NPE..........................................................................................................................yKDR..I..SA..E..SFSFTVPKIV--ee........................................................................................................
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D7SKK8_VITVI/4-80                     ......................................................................................qiesstf---------KL.P..R..DW.VVRKV..R....R...A..S...G.K.SC......................................................GLI.DKYYY.E.............................................................P..eTG.R..Q.FRSL..KSIQKY...LTE.KME...........................................................................................................................-NT..-..--..-..------------pkilgpdkeeeeeqphqk........................................................................................
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M1CS15_SOLTU/12-84                    ........................................................................................deivs------VELAA.P..P..SW.KKLFT..-....P...K..Q...G.G.TP......................................................KKS.EVVFI.T.............................................................P...TG.E..E.VKNR..KQLEQY...LKA.HPG...........................................................................................................................--N..P..AI..A..EFDWSTGET---prr.......................................................................................................
F7FBM5_MACMU/1-91                     ...........................................................................................ma--EDWLDCPAL.G..P..GW.KRREV..F....R...K..S...G.A.TC......................................................GRS.DTYYQ.S.............................................................P...TG.D..R.IRSK..VELTRY...LGP.ACD...........................................................................................................................---..-..-L..T..LFDFKQG-----ilcypapkahpvavaskkrkkpsk..................................................................................
A0A077YXJ1_TRITR/90-169               .......................................................................................qeadyl--------KPF.E..K..GW.VREMV..R....R...A..V...V.S.KS......................................................TAA.DIYYT.S.............................................................P...DG.I..K.FRSG..KEIERF...FKA.NPE...........................................................................................................................---..-..--..-..------------kaaglrsdyftfkrillgwngpee..................................................................................
A0A022R6F0_ERYGU/102-199              ........................................................................................emlkr-------PSWL.P..E..DW.KIDLR..V....R...S..S...G.A.TA......................................................GLI.DRYYV.E.............................................................P...SGnR..K.FRSK..NEVVHY...LET.GSKlkrks................................................................................................................tpetdaE--..-..--..-..------------vsetppapkekssgkrkkskpmnsdnips.............................................................................
T1IKR9_STRMM/88-155                   .....................................................................................dqktpvpg-----------.K..S..GW.IREQV..E....R...Q..S...G.A.TG......................................................GQW.DVYFN.P.............................................................P..gQQ.V..K.LRSR..PEVRSY...CEN.ELN...........................................................................................................................---..-..--..-..------------epyvaadydwkp..............................................................................................
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I3M783_SPETR/87-158                   ........................................................................................rgpmy------DDPTL.P..E..GW.TRKLK..Q....R...K..S...G.R.SA......................................................GKY.DVYLI.N.............................................................P...QG.K..A.FRSK..VELIAY...FEK.VGD...........................................................................................................................-TS..L..DP..N..DFDFTV------tgr.......................................................................................................
F7FBP1_MACMU/1-91                     ...........................................................................................ma--EDWLDCPAL.G..P..GW.KRREV..F....R...K..S...G.A.TC......................................................GRS.DTYYQ.S.............................................................P...TG.D..R.IRSK..VELTRY...LGP.ACD...........................................................................................................................---..-..-L..T..LFDFKQG-----ilcypapkahpvavaskkrkkpsk..................................................................................
F1RZT9_PIG/21-97                      ........................................................................................rgpmy------DDPTL.P..E..GW.TRKLK..Q....R...K..S...G.R.SA......................................................GKY.DVYLI.N.............................................................P...QG.K..A.FRSK..VELIAY...FEK.LQ-...........................................................................................................................---..-..--..-..------------elaevgdapkgvaprdprqqr.....................................................................................
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T1IS30_STRMM/374-443                  ........................................................................................apmls-----------.K..P..GW.EREEV..K....R...Q..T...G.I.TK......................................................GKW.DVYFY.A.............................................................P..gRR.A..P.LRSR..PELKEY...CEQ.EL-...........................................................................................................................RVK..F..NA..D..DFDWVPLQE---kp........................................................................................................
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A0A0D3CAG4_BRAOL/169-265              ........................................................................................tdelv-----SIELPA.P..T..SW.KKLFY..P....K...R..A...G.T.P-......................................................RKT.EIVFM.A.............................................................P...TG.E..E.ISSR..KQLEQY...LKA.HPGnp......................................................................................................................lvkA--..-..--..-..------------ttptpdkepllkkrrssltkkdnkeaaeknqvaq........................................................................
E1ZNZ3_CHLVA/37-140                   ........................................................................................keffv-----EKGQPL.E..E..GW.RVEVK..I....R...G..S...G.T.SL......................................................GTT.DAYYF.S.............................................................P...GN.K..R.YRSR..MEIARD...LG-.---...........................................................................................................................---..-..--..-..------------vvegkegkgsgkgrsrmgegsgggaapppltrdaaiaaarkrrreftlpr........................................................
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G7PWT2_MACFA/1-37                     .............................................................................................-----------.-..-..--.-----..-....-...-..-...-.-.--......................................................---.----F.S.............................................................P...SG.K..K.FRSK..PQLARY...LGN.TVD...........................................................................................................................---..-..-L..S..SFDFRTGKMMP-s.........................................................................................................
F0YB93_AURAN/20-114                   .........................................................................................veew-----GGDASM.L..D..GW.RTEVH..D....R...P..T...G.S.SA......................................................GTT.DRYYF.D.............................................................E...FG.K..R.FRSK..AEIARA...LGL.AGA...........................................................................................................................---..-..--..-..------------paparraseapapprdrtydardgaaayalsasvaaec....................................................................
B4HJY2_DROSE/9-104                    .............................................................................................IERKRVDCSVL.P..K..GW.QRDEV..-....R...K..S...G.S.SAnsnassnnns.................................ssatassnnnnNKV.DVFYY.S.............................................................P...TG.K..R.AEGK..PQDIAI...PDF.QS-...........................................................................................................................---..G..KM..P..HRALPSPS----islyrcs...................................................................................................
I1PJ97_ORYGL/51-113                   .......................................................................................gnnltr------THEWL.P..K..GW.RVEIR..-....-...A..G...G.D.NM......................................................DKM.YKFYV.Y.............................................................P..pDR.V..R.LFSK..DDVLLY...IKE.MK-...........................................................................................................................---..-..--..-..------------isefdtd...................................................................................................
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C5YK76_SORBI/26-90                    .....................................................................................idalaepp--------DWL.P..D..GW.IMEVY..-....R...T..E...D.-.--......................................................GTI.TRYYT.S.............................................................P..iSN.Y..T.FTSK..AEVLEY...LFS.RTD...........................................................................................................................---..-..--..-..------------drileskeyg................................................................................................
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V4LV48_EUTSA/82-155                   ......................................................................................wvidkpg-------LPKT.P..K..GF.KRSLV..L....R...K..D...-.-.-Y......................................................SKM.DTYYI.T.............................................................P...TG.K..K.LRSR..NEVASY...VEA.NPE...........................................................................................................................FKN..A..PL..G..DFTFTVPKVM--ed........................................................................................................
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C5YSF0_SORBI/16-98                    ........................................................................................aeevv-----SVEMPA.P..D..GW.TKKFT..-....P...K..R...G.-.--......................................................GRS.EIVFV.S.............................................................P...TG.E..E.IKNK..RQLSQY...LKA.HPG...........................................................................................................................--G..P..AS..S..EFDWGT------gdtprrsarisekvkvfd........................................................................................
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H0X6Q2_OTOGA/758-810                  ............................................................................................v-TDERELRIPL.E..Y..GW.QRETR..I....R...N..F...G.G.R-......................................................LQG.EVAYY.A.............................................................P...CG.K..K.LRQY..PEVIK-...---.---...........................................................................................................................---..-..--..-..------------gmq.......................................................................................................
A9S602_PHYPA/24-89                    ........................................................................................lagsl-----------.-..Q..GW.KRKLS..E....T...R..G...G.T.P-......................................................KKK.VVSFL.T.............................................................P...DG.E..E.IRNK..TQLNKY...LKA.HPG...........................................................................................................................--T..V..VV..T..DFDWGS------pafep.....................................................................................................
T1ILU4_STRMM/235-301                  ................................................................................kprskverapvpg-----------.K..S..GW.VREQV..Q....R...Q..S...G.A.TA......................................................GQW.DVYFY.P.............................................................P..gQQ.V..K.LRTR..PEVRSY...CKN.ELN...........................................................................................................................---..-..--..-..------------epyvaa....................................................................................................
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M7BC97_CHEMY/74-148                   ......................................................................................evasrcl--------RNV.P..D..GW.EKITK..Q....R...Q..S...G.K.TA......................................................GKY.DFYFI.S.............................................................P...QG.A..K.LRSK..CALVAY...FSK.NG-...........................................................................................................................ETV..L..KP..E..DFDFTAPVQS--kt........................................................................................................
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G3VAD6_SARHA/545-619                  ...........................................................................................ia--TPEEVRFPL.Q..H..GW.RREVR..I....K...K..-...G.S.HR......................................................WQG.ETWYY.G.............................................................P...CG.K..R.MKQF..PEVIKY...LSR.NV-...........................................................................................................................VHH..V..RR..E..HFSFSPRMPV--gd........................................................................................................
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F1RK20_PIG/155-227                    ..........................................................................................kge----NPLQLPI.K..C..HF.QRRHA..-....K...T..-...N.S.HS......................................................SAL.HVSYK.T.............................................................P...CG.R..S.LRNV..EEVFRY...LLE.TE-...........................................................................................................................CNF..L..FT..D..NFSFNTYV----qltr......................................................................................................
A7RR44_NEMVE/9-74                     ....................................................................................rasvitneg----------V.P..T..GW.VKIVT..Q....R...S..K...G.K.TK......................................................GTY.DVYIV.D.............................................................P...DG.R..K.FRSK..AELKRF...LDK.SQS...........................................................................................................................--D..L..TI..E..DFDF--------..........................................................................................................
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F7F4Z3_MONDO/150-221                  ......................................................................................venplmi---------PI.L..C..RF.QRRHA..-....-...K..T...N.S.NY......................................................ATF.HVNYK.T.............................................................P...CG.R..S.LRNF..KEVHRY...LLE.TE-...........................................................................................................................SSF..L..FL..H..NFSFNTYV----qlnr......................................................................................................
I3M1H1_SPETR/46-118                   ..........................................................................................kge----NPLQLPI.K..C..HF.QRRHA..-....K...T..-...N.S.HS......................................................SAL.HVSYK.T.............................................................P...CG.R..S.LRNV..EEVFRY...LLE.TE-...........................................................................................................................CNF..L..FT..D..NFSFNTYV----qltr......................................................................................................
A0A096M5K9_POEFO/80-173               ..........................................................................................eeg----WVEWPVL.G..Q..GW.KRKEV..V....R...R..S...G.S.SI......................................................GQK.DVYYL.S.............................................................P...RG.D..R.VRSR..VELATV...LQG.TDL...........................................................................................................................---..-..--..-..------------tqfeyksgkfvegeippvrgrprtklqrfaalpyvse.....................................................................
H9GLF6_ANOCA/60-130                   ...........................................................................................lc-------HKGV.P..E..GW.ERIVK..Q....R...Q..A...G.K.TA......................................................GKY.DIYFV.S.............................................................P...QG.K..K.LRSK..HALLDY...FKK.NR-...........................................................................................................................ETG..L..KL..E..DFDFTTSV----qnnk......................................................................................................
T1IND1_STRMM/86-156                   .......................................................................................rtpipn-----------.K..P..GW.KRVEV..Q....R...Q..S...G.A.TK......................................................GKW.DIYFY.A.............................................................P...GR.K.iP.LRSR..PELRDY...CEQ.ALK...........................................................................................................................-IP..Y..NP..D..EFNWKP------seplv.....................................................................................................
B4J4D7_DROGR/937-1005                 .........................................................................................dsys-----PLAKPL.L..S..GW.ERLVF..K....Q...K..-...-.-.--......................................................AKR.NVVYR.G.............................................................P...CG.K..S.FRNL..AEVHMY...LRA.TDN...........................................................................................................................--V..L..NV..E..NFDFTPDLRC--la........................................................................................................
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