GenomeNet

Database: Pfam
Entry: MCR_C
LinkDB: MCR_C
Original site: MCR_C 
#=GF ID   MCR_C
#=GF AC   PF04609.7
#=GF DE   Methyl-coenzyme M reductase operon protein C
#=GF AU   Kerrison ND, Finn RD, Mian N
#=GF SE   DOMO:DM04514;
#=GF GA   25.00 25.00;
#=GF TC   29.70 29.00;
#=GF NC   20.00 20.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   8863453
#=GF RT   Phylogeny of Methanopyrus kandleri based on methyl coenzyme M
#=GF RT   reductase operons. 
#=GF RA   Nolling J, Elfner A, Palmer JR, Steigerwald VJ, Pihl TD, Lake
#=GF RA   JA, Reeve JN; 
#=GF RL   Int J Syst Bacteriol 1996;46:1170-1173.
#=GF RN   [2]
#=GF RM   3170483
#=GF RT   Structure and comparative analysis of the genes encoding
#=GF RT   component C of methyl coenzyme M reductase in the extremely
#=GF RT   thermophilic archaebacterium Methanothermus fervidus. 
#=GF RA   Weil CF, Cram DS, Sherf BA, Reeve JN; 
#=GF RL   J Bacteriol 1988;170:4718-4726.
#=GF DR   INTERPRO; IPR007687;
#=GF CC   Methyl coenzyme M reductase (MCR) catalyses the final step in
#=GF CC   methanogenesis. MCR is composed of three subunits, alpha
#=GF CC   (Pfam:PF02249), beta (Pfam:PF02241) and gamma (Pfam:PF02240)
#=GF CC   [1]. Genes encoding the beta (mcrB) and gamma (mcrG) subunits
#=GF CC   are separated by two open reading frames coding for two proteins
#=GF CC   C and D [2]. The function of proteins C and D (this family) is
#=GF CC   unknown. This family nowalso includes family MtrC_related,
#=GF SQ   122
#=GS Q64ED5_9ARCH/1-259   AC Q64ED5.1
#=GS H8IAT5_METCZ/1-270   AC H8IAT5.1
#=GS O27248_METTH/1-272   AC O27248.1
#=GS Q6LWZ7_METMP/1-147   AC Q6LWZ7.1
#=GS Q8PYE5_METMA/1-275   AC Q8PYE5.1
#=GS A7I5U1_METB6/1-151   AC A7I5U1.1
#=GS A4FVW8_METM5/1-146   AC A4FVW8.1
#=GS D2ZPK8_METSM/1-271   AC D2ZPK8.1
#=GS F8AMB8_METOI/1-266   AC F8AMB8.1
#=GS H1YXI1_9EURY/27-151  AC H1YXI1.1
#=GS Q12TF6_METBU/26-143  AC Q12TF6.1
#=GS Q0W341_UNCMA/1-201   AC Q0W341.1
#=GS D9PY38_METTM/1-272   AC D9PY38.1
#=GS F0T8R1_METSL/1-144   AC F0T8R1.1
#=GS A2SQW7_METLZ/1-276   AC A2SQW7.1
#=GS C7P6P0_METFA/1-266   AC C7P6P0.1
#=GS MCRC_METVO/9-178     AC P11567.1
#=GS Q648Y5_9ARCH/25-149  AC Q648Y5.1
#=GS D1YVW4_METPS/27-148  AC D1YVW4.1
#=GS MCRC_METJA/1-150     AC Q58254.1
#=GS Q64EG7_9ARCH/23-204  AC Q64EG7.1
#=GS A5ULZ8_METS3/1-271   AC A5ULZ8.1
#=GS D7DR20_METV3/1-266   AC D7DR20.1
#=GS A9A6L1_METM6/1-266   AC A9A6L1.1
#=GS F6D2E3_METSW/1-271   AC F6D2E3.1
#=GS Q648D1_9ARCH/24-193  AC Q648D1.1
#=GS H1Z437_9EURY/1-277   AC H1Z437.1
#=GS F6BBU5_METIK/1-266   AC F6BBU5.1
#=GS D7E8X9_METEZ/26-144  AC D7E8X9.1
#=GS Q8TXL1_METKA/15-143  AC Q8TXL1.1
#=GS D2ZPL2_METSM/1-197   AC D2ZPL2.1
#=GS A6UQK3_METVS/1-146   AC A6UQK3.1
#=GS Q6M050_METMP/1-266   AC Q6M050.1
#=GS C7P872_METFA/25-194  AC C7P872.1
#=GS A0B6G1_METTP/1-271   AC A0B6G1.1
#=GS Q64A52_9ARCH/1-259   AC Q64A52.1
#=GS Q6VUB2_9ARCH/2-193   AC Q6VUB2.1
#=GS F6D2D5_METSW/1-192   AC F6D2D5.1
#=GS A6UWH0_META3/1-146   AC A6UWH0.1
#=GS D7DUH3_METV3/1-145   AC D7DUH3.1
#=GS Q2FRP7_METHJ/1-276   AC Q2FRP7.1
#=GS F4BSZ7_METCG/25-215  AC F4BSZ7.1
#=GS G6FIY0_9EURY/1-276   AC G6FIY0.1
#=GS Q649M2_9ARCH/1-259   AC Q649M2.1
#=GS B9AF08_METSM/1-271   AC B9AF08.1
#=GS D5VUD0_METIM/1-266   AC D5VUD0.1
#=GS D3S580_METSF/25-150  AC D3S580.1
#=GS D5EAD8_METMS/1-142   AC D5EAD8.1
#=GS MCRC_METVA/1-146     AC P07960.1
#=GS Q2NI65_METST/1-270   AC Q2NI65.1
#=GS Q64C72_9ARCH/25-149  AC Q64C72.1
#=GS Q8PXH6_METMA/2-143   AC Q8PXH6.1
#=GS D5E857_METMS/1-277   AC D5E857.1
#=GS D9PWH5_METTM/8-95    AC D9PWH5.1
#=GS E3GZ53_METFV/1-192   AC E3GZ53.1
#=GS Q46EL3_METBF/1-274   AC Q46EL3.1
#=GS A9A9A4_METM6/26-194  AC A9A9A4.1
#=GS O26698_METTH/12-92   AC O26698.1
#=GS G0H3B1_METMI/1-147   AC G0H3B1.1
#=GS Q49175_METFE/26-145  AC Q49175.1
#=GS G7WKD8_METH6/1-266   AC G7WKD8.1
#=GS Q647K9_9ARCH/24-192  AC Q647K9.1
#=GS A5ULZ4_METS3/1-143   AC A5ULZ4.1
#=GS Q64AP9_9ARCH/2-209   AC Q64AP9.1
#=GS Q64BI9_9ARCH/1-131   AC Q64BI9.1
#=GS G6FIP5_9EURY/2-151   AC G6FIP5.1
#=GS Q64A15_9ARCH/23-204  AC Q64A15.1
#=GS E3GWV5_METFV/1-269   AC E3GWV5.1
#=GS F6BE95_METIK/25-194  AC F6BE95.1
#=GS F7XL12_METZD/26-142  AC F7XL12.1
#=GS G7WN56_METH6/25-227  AC G7WN56.1
#=GS F6D2L3_METSW/1-85    AC F6D2L3.1
#=GS A3CT48_METMJ/26-151  AC A3CT48.1
#=GS D5VQV0_METIM/1-146   AC D5VQV0.1
#=GS E3GZA3_METFV/1-82    AC E3GZA3.1
#=GS A6VJ56_METM7/1-266   AC A6VJ56.1
#=GS MCRC_METBF/26-144    AC P07959.1
#=GS E1RDX6_METP4/1-200   AC E1RDX6.1
#=GS H1KXL7_9EURY/25-194  AC H1KXL7.1
#=GS A6US32_METVS/1-276   AC A6US32.1
#=GS Q2NI35_METST/29-156  AC Q2NI35.1
#=GS D7EBD8_METEZ/1-275   AC D7EBD8.1
#=GS F0T7K3_METSL/1-90    AC F0T7K3.1
#=GS A0B6L3_METTP/25-195  AC A0B6L3.1
#=GS G0H350_METMI/1-266   AC G0H350.1
#=GS Q8TXS7_METKA/1-275   AC Q8TXS7.1
#=GS A6UWA9_META3/1-266   AC A6UWA9.1
#=GS Q12UT6_METBU/1-275   AC Q12UT6.1
#=GS MCRC_METTH/1-192     AC O27234.1
#=GS A4FZ81_METM5/1-266   AC A4FZ81.1
#=GS D1YXG5_METPS/1-270   AC D1YXG5.1
#=GS A7IB43_METB6/1-276   AC A7IB43.1
#=GS H1KYG2_9EURY/1-266   AC H1KYG2.1
#=GS C9RHQ2_METVM/1-266   AC C9RHQ2.1
#=GS D3S8N3_METSF/1-266   AC D3S8N3.1
#=GS Y094_METJA/5-270     AC Q57559.1
#=GS Q49603_9EURY/18-134  AC Q49603.1
#=GS F7XKF1_METZD/1-275   AC F7XKF1.1
#=GS A3CX85_METMJ/1-277   AC A3CX85.1
#=GS A2STS1_METLZ/2-202   AC A2STS1.1
#=GS D3E052_METRM/26-193  AC D3E052.1
#=GS D1JFS8_9ARCH/2-210   AC D1JFS8.1
#=GS A6VHE5_METM7/26-147  AC A6VHE5.1
#=GS Q6VUA3_9ARCH/25-149  AC Q6VUA3.1
#=GS Q2FSN2_METHJ/2-151   AC Q2FSN2.1
#=GS Q64E09_9ARCH/2-193   AC Q64E09.1
#=GS D3E057_METRM/1-271   AC D3E057.1
#=GS D1JIA4_9ARCH/1-263   AC D1JIA4.1
#=GS Q8TIZ7_METAC/1-275   AC Q8TIZ7.1
#=GS Q0W8W5_UNCMA/1-270   AC Q0W8W5.1
#=GS B8GJ60_METPE/1-276   AC B8GJ60.1
#=GS F0T8Q6_METSL/1-271   AC F0T8Q6.1
#=GS MCRC_METTM/1-192     AC P11566.1
#=GS Q8THG9_METAC/26-143  AC Q8THG9.1
#=GS H8I4A9_METCZ/1-198   AC H8I4A9.1
#=GS G9BY96_9ARCH/1-151   AC G9BY96.1
#=GS B8GE91_METPE/26-151  AC B8GE91.1
#=GS C9REL3_METVM/1-146   AC C9REL3.1
#=GS E1RIS0_METP4/1-277   AC E1RIS0.1
#=GS B9AF04_METSM/1-147   AC B9AF04.1
#=GS F8AMU2_METOI/27-194  AC F8AMU2.1
#=GS F4BVZ9_METCG/1-271   AC F4BVZ9.1
Q64ED5_9ARCH/1-259              .............................-.---MMFEGGVYKFYELKELVGDL....GGFILQESV.........MQ.........T.........ETMMHLAFPEEDEREIRNKIKELGGKFKELPLAGTEIIIVVPSLGKHHAVDPMCDIAEFLRRSGAI..T..NM..MGLARGVG..............RRIAQMTTQEKQIIEEFDAAVFIFGTFEECIEE-KVKLCKSID.IP.YIIVGGPSDMKLEH-...............YVGGVGRK.TARMRSK.D.E.IDLLYDVASELERALAEKRLDIEEDPIAASPLFIKDM..........IEKTI--LPKTGEELPNVIQLDGLRVKIEEEDI-EKIKEIE....................................................
H8IAT5_METCZ/1-270              .............................M.-EPFIFQGGLYKHEEFEELVEDL....GGYILQKNV.........LQ.........L.........DVIMVVLVPNADIPVVEAKARELLAKLTKAPLAGAEVAVVTPTLAYQHLPHLACDIAEYLRRSGSK..T..NM..IGLARGVG..............KRLAQLTAKEVDLINEHDAALFLYGNFRECIRE-KTKLFQDIE.VP.IVVAGGP-MMEASEVpg..........ceaYVGGLGRM.MHRLRQK.D.E.TARMDAIVAAIGKVLDERRAEFDKDPLSVSPPRVKAE..........IEKQVPDIQDSISPTPVTLNLNGARIKLPYDEYKDTILNV-r...................................................
O27248_METTH/1-272              .............................M.YETLTYQGGVHRHEEMKELIEDL....GGFVLQENM.........LQ.........M.........DLILTLAVPIDDVDKVREKARELLGKIKVAPMAGTEIAIVSPTLARHHLPHSACDISEYLRRYGAK..D..NM..IGLARGAG..............KGISRISEDEKRLIEEHDLAVFALGSFEQCIKD-KVHLFSDIK.IP.VVVTGSPDEIDLRDLpg..........adaYVGGLGRI.PRRLKRG.E.D.IRALRKLVEVVEGLLDKRSRDMAADPPLVPSILVKSE..........IENQVPAIKEVYSPTPVTSQLDGVRVKLNYDRYHEEIADV-r...................................................
Q6LWZ7_METMP/1-147              ...mpvgrkeqivdcravmglgeggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEG--LRNDVVVVAMSPGRRHITKPVCEITYGIREAGIQ..T..SV..LVLDAGGGipsda....pqgslGSTFGLKPEEAKQVNRHKLCVIHFGNVKSHIIYKARLFLKYVD.IPtIIVCQTPVDME----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------df..................................................
Q8PYE5_METMA/1-275              ..........................mav-.LLPYLYTGGVHKHGLLIELMEDL....GGYIIQKVV.........TG.........T.........EVNLIMLVPEKDVDIVKKLSKELLGILVEAPLTGVEIAVVSPTLASHHLPHSACDVAEYLRHPGAN..T..NM..LGLARGMG..............RRVSLSMDYERKLINEHDIAVFTFGSFSDCITKKKPKLFEGIE.IP.IVVTGGPSDLKTEDIqg..........adlYVGNIGRV.SHRLRRT.E.E.VNALENLNQEVSKIADSIRKQQARDPLAVLPARVMKE..........IENQVPEIRTVLSPAPLTLQLDGVRVKLPYDQFHEKIEKL-e...................................................
A7I5U1_METB6/1-151              ...mpigrvtqvvdcreamgmgkggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTISEC--RYPDVIVVGMSPGRRHVTKPVCDITSGLRQQGVE..YsiST..LVLNAGSGvppdap.niaggviGAYFGLTDKEIVQIERHKVAILHHGNVRSHVVAKVRYVLEACD.VKaIVVSQSPIDY-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
A4FVW8_METM5/1-146              ...mpvgrkeqivdcravmglgeggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEG--LRNDVVVVAMSPGRRHITKPVCEITYGIREAGIQ..T..SV..LVLDAGAGipsda....pqgslGSTFGLKPEEAKQVNRHKLCVIHFGNVKSHIIYKARLFLRYVD.IPtIVVCQSPVDME----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------d...................................................
D2ZPK8_METSM/1-271              .............................M.YETLTYTGGVHKSEEVKELIEDL....GGFILQENI.........LQ.........M.........ELVLNLAIPLEDVDVIKNKAKELLAKVTVAPMAGSEIAIVSPTLARHHLPHAACDISEYLREFGAK..D..NM..IGLARGDG..............KGTSGITEEEKSLIEEHDVAVFALGSFKNCIQE-KSFLYDDIN.VP.VIVTGAP-EIPIEELpg..........adaYVGGLGRI.PRRLKRG.P.D.IRALNNLVDTIETILNNKKREMALDPPLVPSIVVKNA..........IENQVPAIEDIISPAPITVQLDGVRVKLNYDKYHELIENV-v...................................................
F8AMB8_METOI/1-266              .............................M.YEIIRYEGGVYKNNILKEWIEDV....GGFIIQEHV.........MQ.........L.........DVYMTIALPQNEIENFKIESKKYKGKVVETPLAGTEIAIVAPSLSRHHLPHTACDISEFVRRFGAK..P..NM..IGLSHGAG..............KDISLIKEKEKRLIEEHDIAVYVMGNFESCLLD-KTHLFE-VD.IP.VVITGGPETLGIPYP...............YVGNLGRR.AHRLRHS.E.E.RQALKKMVNEITRLIDRKREELSYDPPIIPPVVLKDE..........LEKQVDEIFNILSPMPIVTQLDGLRIKLNYDTYHEKIENVK....................................................
H1YXI1_9EURY/27-151             ............................r-.-----------------------....---------.........--.........-.........------------------------GTISEC--RHPDVIVVGMSPGRRHVTKPVCDITSGLRREGVEfsV..ST..LVLNAGSGvppdap.aiagsvlGAYFGLNSKEIAQIEQHKVAILHHGNVRSHVVEKVRFILERCD.TDaIVVSQAPVDY-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
Q12TF6_METBU/26-143             ............................r-.-----------------------....---------.........--.........-.........------------------------GTLSET--GRPDVIAVAMSPGRRHITKPICELTYGMRREEIQ..V..SV..LVLNSGSGipd.......tpmrSGSFGITPEEIAQISRHKLAVIHTGNIRDHVVKKVREILKEAD.TPaIVVCQANIDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------edl.................................................
Q0W341_UNCMA/1-201              ....mpidretqvvdcresmgldkgggla-.-----------------------....-----Q---.........--.........-.........-----------------------RGTLSET--GRPDVVAIAMTPGRRHITKPVCEITHGLRKEGIQ..V..SV..LVLYSGGGvpsdae..daaighGPKFGLNEKEIEQIRRHKVALIHLGNVKSHVIYKARDILRFVD.IPaIIVCQAPVDF--ED-...............-FARIGVK.TRVVQPP.E.DkVETQGTVVEIV--------------------------..........-----------------------------------------tgitrgqtcardklneivkhiieln...........................
D9PY38_METTM/1-272              .............................M.YETLTYQGGVHRHEEMKELIEDL....GGFVLQENM.........LQ.........M.........DLILTLAVPIEDVDKVREKARELLGKVKVAPMAGTEIAIVSPTLARHHLPHSACDISEYLRRYGAK..D..NM..IGLARGAG..............KGISRISEDEKRLIEEHDLAVFALGSFEQCIKD-KAHLFSDIN.IP.VVVTGSPEKIDLSELpg..........adaYVGGLGRI.PRRLKRG.E.D.IRALRKLVEVVEDILDRRRREMAADPPLVPSILVKTE..........IENQVPAVKEVYSPTPVTSQLDGVRVKLNYDRYHDEIADV-r...................................................
F0T8R1_METSL/1-144              ...........................mi-.----------GKATHVVDCRETMgmgeGGGIAQR--.........--.........-.........------------------------GTFAEC---GSEVLAIAMSPGRRHITKPVCEITFALREANIQ..T..ST..LVLNAGAGvpqda....psagaGSLFGLTPKEIEQIKRFRLVVVHLGGVRHHIIYKARLILRHVN.RPcVVICEYPVDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
A2SQW7_METLZ/1-276              ...........................mi-.LVPITYKGGVYRLDEVVDYIEDL....GGYIVQRHN.........IA.........S.........EVVLQVLMPKEDIKRLATFSRPLAGEIQESPLVGTEIAVVIPSLEIHHLPHSACDVAEYLRSHGSK..S..NM..LGMARGFG..............KRIAQMNDEERDLINEHDLAIFVLGNFASCIETKFVKFRPGIT.VP.IILTGGPDREILEKQtdp........pvagYVGGLGRF.MHRTQTE.A.D.IHRLDLVIEEVKKVIEERRQEIANDPLSVSSARLQAL..........IKQELPEIEEVYSPSPIAVQLNGLRLKLSYPSYAQKVRD--lv..................................................
C7P6P0_METFA/1-266              .............................M.YEIVRYEGGVYKNNIFKEWIEDI....GGFIIQEHV.........MQ.........L.........DVYMTLAIPQNELENIKEEAKKYKGKIIETPLAGTEIAVVAPSLSRHHLPHTACDISEYLRRFGAK..P..NM..IGLARGVG..............KDIAQLREKERRLIEEHDLAVYVMGNFEACIKD-KTHLFD-VD.IP.VVVTGGPESIDIPYP...............YVGNLGRR.SHRLRHG.E.E.IRALRKMVNVITELINERRKELSYDPPVVPPVVVKDE..........IEKQVEEIFSVLSPMPIVTQLDGLRVKLDYDKYADKIREVK....................................................
MCRC_METVO/9-178                ..........................laq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEG--LKNDVVVVALSPGRRHLTKPVCEITYGIRESGIQ..T..SV..QVLNAGSGlpad.....apnslGSTFGLKPEEVEQVNRHKLCIIHFGNVKSHVVYKARLFLRFVT.ILtIVVCQTPIDM-----...............--------.-------.-.-.--------EDFAKIGIKTADVIPIEP--KTKGTIVEI..........VTGVVRGESSPQSK---------------------------ideiiekik...........................................
Q648Y5_9ARCH/25-149             ............................q-.-----------------------....---------.........--.........-.........-----------------------RGTLSET--GRPDVIAIAMSPGRRHITKPVCEITHGLRREGIQ..V..SV..LVLEAGAGvpeegpsdrmakgyGPKFGLTQKEIEQISRHRVALIHLGNIDSHVIYKTKYVLKYVD.IPaVIACQNPVDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
D1YVW4_METPS/27-148             ............................r-.-----------------------....---------.........--.........-.........------------------------GTLSET--GRPDVIAIAMTPGRRHITKPVCEVTHGLRREGIQ..V..SV..LVLFSGGGvpsdsk..daaigrGPKFGLSEKEIEQINRHKLALIHLGNVKSHVIYKARDILRFVT.IPaIIVCQTPVDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
MCRC_METJA/1-150                ...mpvgrreqivdcrsvmglgeggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEA--LKNDVVVVAMSPGRRHITKPVCEITYGIREAGIQ..T..SV..LVLNAGSGiphda....prgalGSTFGIKPEEAEQINRHKLCVVHFGNVISHIVYKAGLLLKYVE.IPtIIVCQAPVDME----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------dlaky...............................................
Q64EG7_9ARCH/23-204             .........................giaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAKA--WKNDVVAVAMSPGTRHVPKPVCEITTELRGKGLS..T..GV..IVLNAGNGtprda...prtgghGSIFGLEQKEIDIIGGHKLAVLHHGNVKEHFIYKVRLELKKIP.ISaIILCQSPVEFVEFEQigvstrnkecetpgkVVGIVSGI.VRRESVP.Q.-.-DKLDEIVSKV--------------------------..........-----------------------------------------rmclreieeseek.......................................
A5ULZ8_METS3/1-271              .............................M.YETLTYTGGVHKSEEVKELIEDL....GGFILQENI.........LQ.........M.........ELVLNLPIPLEDVDVIKNKAKELLAKVTVAPMAGSEIAIVSPTLARHHLPHAACDISEYLREFGAK..D..NM..IGLARGDG..............KGTSGITEEEKSLIEEHDVAVFALGSFKNCIQE-KSFLYDDIN.VP.VIVTGAP-EIPIEELpg..........adaYVGGLGRI.PRRLKRG.P.D.IRALNNLVDTIETILNNKKREMALDPPLVPSIVVKNA..........IENQVPAIEDIISPAPITVQLDGVRVKLNYDKYHELIENV-v...................................................
D7DR20_METV3/1-266              .............................M.YQIVRYEGGVYKHNELKEWIEDV....GGFIIQEHV.........MQ.........L.........DVFMTVAFPEDEIGEFKALSKNYKGKVVETPLAGIEIAVVAPSLSRHHLPHIACDVSEYVRKFGAK..P..NM..IGLSHGAG..............KSISQIKEKEKRLIEEHDLAIYVMGNFKSCIED-KTHLFE-VD.IP.VIITGGPQSIEVDKT...............YIGNLGRR.SQRLRRG.S.E.IRALDSMIEKITEKIGEKRLELSYDPPIIPPVVLKDE..........IEKNIADVHGIFAPMPIVTQLDGLRIKLDYDRSHEKIENLK....................................................
A9A6L1_METM6/1-266              .............................M.YEIIRYEGGVYKNNILKEWIEDV....GGFIIQEHV.........MQ.........L.........DVYMTIAIPHNEIENFKEEAKNYKGKVVETPLAGIEIAIVSPSLSRHHLPHIACDVSEYVRKFGAK..P..NM..IGLAHGAG..............KSISQINEKEKRLIQEHDIAIYVMGNFESCILD-KTHLFK-ID.LP.LVVTGGPETLDIPYT...............YVGNLGRR.AQRLRKG.E.E.IRALRRMIDEVTKKINDRRLELSYDPPIIPPVVLKDE..........IEKKIDEVRGLLAPMPIVTQLDGLRIKMDYDRNHEEIENVK....................................................
F6D2E3_METSW/1-271              .............................M.YETLTYTGGIHKHEEMNELIEDL....GGFVLQETT.........SQ.........M.........DLVLTLAVPIEDVDKVKEKAKQLLGKVQIAPMAGTEIAVVSPTLARQHLPHSACDISEYLRRYGAK..D..NM..IGLARGAG..............KGISRISEDEKNLIEEHDLAVFALGSFKECITN-KTHLFEDIE.IP.VVVTGAP-NIDVSEIpg..........adaYVGGLGRI.PRRLKRG.E.D.IRALRKLVEVVEGILDKKRVEMADDPPIVPSILVKTE..........IENQVPAVKEIYSPLPVVSQLDGVRVKLNYDDYHEEISKV-v...................................................
Q648D1_9ARCH/24-193             ..........................maq-.-----------------------....---------.........--.........-.........-----------------------RGTFAKA--RQNDVIALAMSPGYRHVPKPVCQITTELRGRGIN..T..GE..LVLNAGDGtpeda...pkggghGVAFGLEPREVDIIGRHKLAILHHGNVKSHFIYKVRFELRKVA.IPaIVLCQCPVEFEDFE-...............---EIG-V.STRNKEG.E.T.PGKIMDIVTG---------------------------..........-----------------------------------------ivrnsdvpqeklneivskvkm...............................
H1Z437_9EURY/1-277              .............................MtFVPITYKGGVYKHDIILDLIDDL....GGHIVQKHM.........IA.........Q.........DVVLQCLVPKEDIPLIKETGRPFGSEVFESPLVGTEIAVISPSLEIHHLPHTSCDVAEYLRSAGAK..T..NM..IGLARGFG..............KRIANLNIEERDIINEHDCAVLMLGNFESCIRHKLPALRRGIK.VP.IILTGGPDTESLSVLadp........plegYVGNIGRI.GHRMKKQ.EgE.IEYLDDLVDVISGVLDEKREEIAKDPLSISPAKLMST..........LDEEMQITKGSTHPTPITVQTAGLRVKIPYGEYADEVSAVE....................................................
F6BBU5_METIK/1-266              .............................M.YEIVRYEGGVYKNNILKEWIEDI....GGFVIQEHV.........MQ.........L.........DVYMTVALPQSEIEAFKEEAKKYKGKVVETPLAGIEIAVVAPSLSRHHLPHTACDISEYVRRFGAK..P..NM..IGLAHGAG..............KSISRISEREKKLIEEHDIAIYVMGNFANCIKD-KTHLFD-VD.IP.VVVTGGPEELDIPYP...............YVGNLGRR.AHRLRHG.E.E.IRALRKMIDVVTELINERRKELSYDPPIVPPVVVKDE..........IEKRVEEVFNILSPMPIVTQLDGLRIKMDYDKYKDKIANVK....................................................
D7E8X9_METEZ/26-144             ...........................aq-.-----------------------....---------.........--.........-.........-----------------------EGTLSEA--ARPDVIAVAMGPGRRHITKPVCELTYGMRQAGIQ..V..SV..LVLSGGTGqpe.......sgliSGSFGIEPEETDQIARHKLAVIHVGNVAQHIIKKIRKILENVE.IPaIVVSQALVDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
Q8TXL1_METKA/15-143             ...................gmgkggslaq-.-----------------------....---------.........--.........-.........-----------------------RGTIAET--EITEVVAVAMSPGSRHITKPVCEITYALREAGIH..T..SV..LVLNAGSGvpae.....apvqtGATMGIEPEEIERINRHEVAVIHLGNVKQHIVWKARLILKHCD.VPaVIVCQTPVDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
D2ZPL2_METSM/1-197              mtfkmigrcthvvdcratggmgkggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEC---GAEVLAVAMSPGRRHITKPVCEITFGLRESNVL..T..ST..MVLNAGAGvphd.....apasgGTLFGLTDKEVEQMSNFKLLVIHLGGVKNHLIYKARLILRNVN.KPcIIICESSVDC-----...............--------.-------.-.-.--------EDFAKIGVKTSKVMPSEEDVKTEGHIVDI..........VSGVIRGETIS------------------------------qekldeiirkvk........................................
A6UQK3_METVS/1-146              ...mpvgrkeqivdcravmglgeggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEG--LRNDVVVVAMSPGRRHITKPVCEITYGIREAGIQ..T..SV..LVLDAGGGipsda....pqgslGSTFGLKPDEARQVNRHKLCVIHFGNVKSHIIYKARLFLKYVT.IPtIIVCQSPVDME----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------d...................................................
Q6M050_METMP/1-266              .............................M.YQIIRYEGGVYKNNILKEWIEDV....GGFIIQEHV.........MQ.........L.........DVYMTIAIPQNEIENFKEEAKKYKGKIVETPLAGIEIAIVSPSLSRHHLPHIACDVSEYVRKFGAK..P..NM..IGLAHGAG..............KNISEIREKEKRLIQEHDIAIYVMGNFESCILD-KTHLFK-VD.IP.LVVTGGPETLDIPYT...............YVGNLGRR.AQRLRKG.E.E.IRALRQMIDEVTKKINDKRMELSYDPPIIPPVVLKDE..........IEKRIDEVRGILAPMPIVTQLDGLRIKMDYDRNHEEIENVK....................................................
C7P872_METFA/25-194             ...........................aq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEA--LRNDVVVVAMSPGRRHITKPVCEITYGIREAGIQ..T..SV..LVLNAGSGiphda....prgalGSTFGIKPEEAEQINRHKLCVVHFGNVISHIVYKAELLLKYVK.IPtIIVCQAPVDM-----...............--------.-------.-.-.--------EDLAKYGIKTRNVMPLEP--KTEGMVVDI..........VTGVIRGE------------------SCPQSKIDEIIR---kik.................................................
A0B6G1_METTP/1-271              .............................M.LEPVMFTGGVYKHDLVIELVEDL....GGYLLQKNV.........TQ.........S.........EVILLLLVPAEDLRILEDLTKELRGELTRAPLAGTEVAVVTPTLAIHHLPHTACDIAEYLRRNGAK..S..NM..IGLARGVG..............REIAQINEYETALINEHDAAVFIFGNFVKCIIK-KEELYKGVN.IP.VVVTGGP-EIPKGEMpy..........afeYVSSVGRI.AHRSKKA.N.E.IGNLDRIVAAVGRALDKMRADIEKDPLTTSPPRVMDV..........VREQVPDIERSYSPLPIALNLNGCRIKLPYDEYHDAIGNV-m...................................................
Q64A52_9ARCH/1-259              .............................-.---MMFEGGVYKFYELKELIGDL....GGFILQESV.........MQ.........T.........ETMMHLAFPEEDEREIRNKIKELGGKFKELPLAGTEIIIVVPSLGKHHAVDPMCDIAEFLRRSGAI..T..NM..MGLARGVG..............RRIAQMTTQEKQIIEEFDAAVFIFGTFEECIEE-KVKLCKSID.IP.YIIVGGPSDMELEH-...............YVGGVGRK.TARMRNK.D.E.IDRLYDVASELERALAEKRLDIEEDPIAASPLFIKDM..........IEKTI--LPKTGEELPNIIQLDGLRVKIEEEDI-EKIKEIE....................................................
Q6VUB2_9ARCH/2-193              ....vvgrktqlvacrkgqalglgggiaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAKA--RQNDVIALAMSPGYRHVPKPVCQITTELRGRGIN..V..GE..IVLNAGDGtpads...pssgghGVAFGLQANEMEIIGMHKLALLNHGNVKAHFIYKVRFELRKVA.IPaIVLCQCPVTFEDF--...............--EEIG-V.STRNKEG.E.T.PGKVMEIVTGI--------------------------..........-----------------------------------------vrnadvpqaklneivskvkm................................
F6D2D5_METSW/1-192              ...........................mi-.----------GKSTHVVDCRETMgmgeGGGIAQR--.........--.........-.........------------------------GTFAQC---GSEVLAIAMSPGRRHITKPVCEITFALREANIQ..T..ST..LVLNAGSGvpqda....ptaghGSLFGLTPKEIEQIKRHRVVVVHLGGVKHHIIYKARLILRNVN.RPcVIICEYPVDF-----...............--------.-------.-.-.--------EDFAQIGVKTKAVMPEEP--KTQGEIVDI..........ISGVIRGE------------------TCPQEKLDEIIRK--vr..................................................
A6UWH0_META3/1-146              ...mpvgrkeqivdcravrglgeggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEG--LKNDVVVVAMSPGRRHITKPVCEITYGIREAGIQ..T..SV..LVLNAGSGlphdt....pkgslGSTFGLKPEEAKQVNRHKLCIVHLGNVKSHIIYKARLFLRYVK.IPtIIVCQTPIDM-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
D7DUH3_METV3/1-145              ...mpvgrreqivdcravmglgqggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEG--LKNDVVVVAMSPGRRHITKPVCEITYGIRESGIQ..T..SV..LVLNAGSGlpad.....apnslGSTFGLKPEEVEQVNRHKLCVIHFGNVKSHVVYKARLFLRHVN.IPtIVVCQTPIDM-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
Q2FRP7_METHJ/1-276              ...........................mi-.LVPITYKGGVFRHDEILDLIEDM....GGYIIQKHM.........IA.........Q.........EVVLQALIPKEDIEILKTVSRPLAGEVKPAPLVGTEIAVVSMSLEIHHLPHASCDVAEYLRTAGAK..T..NM..IGLARGFG..............KRIGLLSDEERDIINEHDLAIYLFGNFETCIKEKMPTFRRGIQ.VP.IVVCGGPTKETLMKIidp........pvagYIGGLGRF.MHRTKEP.H.E.LARLDEIVEEVSRVIDQKRIGIAKDPLSVTPARLMDI..........ILENVPAIHEVTSPIPVVVQMDGTRIKLPYDPYAAEIREIE....................................................
F4BSZ7_METCG/25-215             ............................q-.-----------------------....---------.........--.........-.........-----------------------RGTLSEA--TKPDVIAIAMSPGRRHITKPVCEMTYGLRREGIQ..T..SV..LVLEAGTGvpesfp..qgsrgyGPTFGLSEKEVEQIARHKIAVFHLGNVRSHVIFKAKEILSQVD.IPaVVVAQCPMDL--EDF..............aKEGVKTRL.VKPSRQKtQ.T.LGEVVDLVTGIT-------------------------..........-----------------------------------------rgatcnrvklnqlakvlnkhlaeiserearelakkq................
G6FIY0_9EURY/1-276              ...........................mt-.HVPVTYKGGIYRHDEIIDLIEDL....GGYIIQKHV.........IA.........Q.........EIVLQALVPREDIELIRRIGKPLTGEVTPSPLVGTEIAVVTPSLEIHHLPHASCDVAEYIRRFGAK..T..NM..VGLARGFG..............KRIAQLNDEERDVINEHDLAVYLLGDFETCIERKFPVLRRGID.VP.IVLCGGPSTEALRRIidp........pvegYVGGIGRF.MHRTKES.E.E.IGKLEEVVGEITRVLDQRREDLARDPLSISPARLMDI..........IAENVEEIHEVLSPTPITVQMQGLRVKLPYDTFAPVIRKL-v...................................................
Q649M2_9ARCH/1-259              .............................-.---MMFEGGVYKFYELKELVGDL....GGFILQESV.........MQ.........T.........ETMMHLAFPGEDEREIRNKIKELGGKFKELPLAGTEIIIVVPSLGKHHAVDPMCDIAEFLRRSGAI..T..NM..MGLARGVG..............RRIAQITTQEKQIIEEFDAAVFIFGTFEECIEE-KVKLCKNID.IP.YIIVGGPSDMELEH-...............YVGGVGRK.TARMRSK.D.E.IDRLYDVASELERGLAEKRLDIEEDPIAASPLFIKDM..........IEKTIPPK--TGEELPNVIQLDGLRVKIEEEDV-EKIKEIE....................................................
B9AF08_METSM/1-271              .............................M.YETLTYTGGVHKSEEVKELIEDL....GGFILQENI.........LQ.........M.........ELVLNLAIPLEDVDVIKNKAKELLAKVTVAPMAGSEIAIVSPTLARHHLPHAACDISEYLREFGAK..D..NM..IGLARGDG..............KGTSGITEEEKSLIEEHDVAVFALGSFKNCIQE-KSFLYDDIN.VP.VIVTGAP-EIPIEELpg..........adaYVGGLGRI.PRRLKRG.P.D.IRALNNLVDTIETILNNKKREMALDPPLVPSIVVKNA..........IENQVPAIEDIISPAPITVQLDGVRVKLNYDKYHELIENV-v...................................................
D5VUD0_METIM/1-266              .............................M.YEIVRYEGGVYKNNIFKEWIEDI....GGFVIQEHV.........MQ.........L.........DVYMTLAIPQSELERIKEEAKKYKGKIIETPLAGTEIAVVAPSLSRHHLPHTACDIAEYLRRFGAK..S..NM..IGLARGVG..............KDIAQLREKEKRLIEEHDLAVYVMGNFSSCIKD-KIHLFD-VD.IP.VVVTGGPKELDIPYP...............YVGDLGRR.SHRLRHG.E.E.IRALRRMVDKITELINKKRKELSYDPPVVPPVVVKDE..........LEKQVEEVLEILSPMPIVTQLDGLRVKLDYDKYHKKIEEVK....................................................
D3S580_METSF/25-150             ...........................aq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEA--LKNDVVVVAMSPGRRHITKPVCEITYGIREAGIQ..T..SV..LVLNAGSGiphda....prgalGSTFGIKPEEAEQINRHKLCVVHFGNVISHIVYKAGLLLKYVK.IPtIIVCQAPVDME----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------dlaky...............................................
D5EAD8_METMS/1-142              ....mfdretqvvdcrhgmglgkggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTLSEA--GRTDVVAVAMSPGRRHITKPVCELTYGMRKEDIQ..V..SV..LVLNSGSGvpd.......eqmkSGSFGINPEEIRQINRHKMAVIHTGNIRDHVVRKVREILVYAE.VPaVVVCQTIVDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
MCRC_METVA/1-146                ...mpvgrkeqivdcravmglgeggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEG--LRNDVVVVAMSPGRRHITKPVCEITYGIREAGIQ..T..SV..LVLDAGGGipsda....pqgslGSTFGLKPDEARQVNRHKLCVIHFGNVKSHIIYKARLFLKYVT.IPtIIVCQSPVDME----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------d...................................................
Q2NI65_METST/1-270              .............................M.YETMTYTGGVHKHYEIEELIEDL....GGFILQKNE.........SQ.........I.........DITLTIAVPSEDTDKIEAKAKELLGSVELSPLASTEIAVVSPTLARQHLPHAACDIAEYLRRYGTK..T..NM..IGLARGAG..............KGIAQINKEEKDLIEEHDLAIFSLGSFDDCIRK-KKFLFEDID.IP.VIVTGSP-EIVAEEIna...........naYVAGFGRI.PRRLKRG.E.N.IRALKKLVKTSEDIISKQKEELSDDPLIISPVIVKIT..........LERELPSIKDVNAPMAIVSQLDGVRVKLPYDEYYKEVANV-v...................................................
Q64C72_9ARCH/25-149             ............................q-.-----------------------....---------.........--.........-.........-----------------------RGTLSET--GRPDVIAIAMSPGRRHITKPVCEITHGLRREGIQ..V..SV..LVLESGAGvpdegpsdrmakgyGPKFGLTQKEIEQISRHRVALIHLGNIDSHVIYKTKYVLRYID.IPaIIACQNPVDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
Q8PXH6_METMA/2-143              ....mfdretqvvdcrcggglgkggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTLSEA--GRADVVAVAMSPGQRHITKPVCEITYGMRKENIQ..V..SV..LVLYSGSGipe.......sgmrTGSFVLSPVEVAQIEMHKLAVIHLGNIKDHVIRKTREILSQVD.IPaIIVSQIPVDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
D5E857_METMS/1-277              .......................mpvaav-.LEPYVYEGGVHKHGLIIELLEDL....GGYLVQSTP.........AA.........T.........EINLVMLIPRKDVPLMEELAKKILGKLTRAPLTGTEIAVVSPTLAYHHLPHSACDVAEHLRRDGAN..T..NM..LGLARGMG..............RRVALSQDYERRLINEHDIAVYSFGNFSDCIMNKKPKLFSGVN.VP.IVATGGP-ELKTEDVeg..........advYVGGIGRV.SHRLRNE.G.E.MDSLDVLNKTVGEVVDKLREEISRDPLAVLPARVMKE..........IKEQVPEINDVLTPAPITLQLDGMRVKLPFGQFHEKLEQL-e...................................................
D9PWH5_METTM/8-95               .............................M.YSLVVFTGGPHNFHELEEFVEDA....GGLIIQRDT.........FSvhrgqyflrN.........EVRVLCIIPSADEETLRETARRIKGEIEGL------------------------------------..-..--..--------..............-------------------------------------------.--.---------------...............--------.-------.-.-.-------------------------------------..........-----------------------------------------dvnqdvleriksl.......................................
E3GZ53_METFV/1-192              ..........................mig-.-----------RTTHIVDCRETMglgeGGGLAQR--.........--.........-.........------------------------GTFAQC---GGDVVAVAMSPGRRHITKPICEITFALRENDIK..V..ST..LVLNAGAGvpsda....peagaGGLFGITPEEAEQIGRHKLALVHLGAVRYHIIYKARLILRNVD.VPcIIVCEYPVDF-----...............--------.-------.-.-.--------EDFAKIGVKTRAVMPDKP--QTKGIVVDI..........VSGVVRGE------------------TCPQEKLDEIVN---kvk.................................................
Q46EL3_METBF/1-274              ..........................mav-.LRPYLYTGGVHKHGLLIELLEDL....GGYIIQKVV.........TG.........T.........EVNLIMLIPEKDIPIVKKQSDELLGMMVEAPLTGVEIAVVSPTLASHHLPHSACDIAEYLRHPGAN..T..NM..IGLARGMG..............RRVSLSMDYERRLINEHDIAVFTFGSFSDCIINKKPKLFEGIE.IP.IVVTGGP-DLKTEEVpg..........adlYVGDIGRT.SHRLRKA.E.E.ISALDKLNEGVGKIADNIRKQQAKDPLAVLPARVMKE..........IENQVPEIRTVLSPAPLTLQLNGLRVKLPYDEFHEKIEKL-e...................................................
A9A9A4_METM6/26-194             ............................q-.-----------------------....---------.........--.........-.........-----------------------RGTFAEG--LRNDVVVVAMSPGRRHITKPVCEITYGIREAGIQ..T..SV..LVLDAGAGipsda....pqgslGSTFGLKPEEAKQVNRHKLCVIHFGNVKNHIIYKARLFLKYVD.IPtIVVCQSPVDM-----...............--------.-------.-.-.--------EDFAAIGIKTRNVMPLET--KTEGTIVEI..........ITGVIRGE---------------------------------sapqkkideiiesik.....................................
O26698_METTH/12-92              .............................M.YSLVVFTGGPHNFHELEEFIEDA....GGIIIQRDT.........FSvhrgqyflrN.........EVRVLCIIPRCDEDSLTETARRIKGEVE--------------------------------------..-..--..--------..............-------------------------------------------.--.---------------...............--------.-------.-.-.-------------------------------------..........-----------------------------------------gldaddet............................................
G0H3B1_METMI/1-147              ...mpvgrkeqivdcravmglgeggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEG--LRNDVVVVAMSPGRRHITKPVCEITYGIREAGIQ..T..SV..LVLDAGGGipsda....pqgslGSTFGLKPEEAKQVNRHKLCVIHFGNVKSHIIYKARLFLKYVD.IPtIIVCQTPVDME----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------df..................................................
Q49175_METFE/26-145             ............................r-.-----------------------....---------.........--.........-.........------------------------GTFAQC---GGDVVAVAMSPGRRHITKPICEITFALRENDIK..V..ST..LVLNAGAGvpsda....peagaGGLFGITPEEAEQIGRHKLALVHLGAVRYHIIYKARLILRNVSmVPcIIVCEYPVDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
G7WKD8_METH6/1-266              .............................-.----MFTGGVYKHDLVTELVEDL....GGYLLQKNV.........TQ.........S.........EVILLMLVPHEDMPVLEALTKELKGKLERAPLAGTEIAVVTPTLAIHHLPHPACDVAEYLRRHGAK..S..NM..IGMSRGVA..............KKIAQMDEYETALINEHDAVVFTFGNFADCILK-KEHLYRTLT.VP.VIVTGGP-DMRKEDLpy..........afeYVPNVGRI.AHRSRKA.T.E.IGSLDNIVAAVGRALDSVRTSISKDPLTTTPPRVMDA..........VREQVPDVLISHSPLPIALNLNGLRIKLPYEEYHEAVAGV-r...................................................
Q647K9_9ARCH/24-192             ..........................iaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAKA--RQNDVIALAMSPGYRHVPKPVCQITTELRGRGIN..V..GE..IVLNAGDGtpads...pssgghGVAFGLQANEMEIIGLHKLALLNHGNVKAHFIYKVRFELRKVA.VPaIVLCQCPVTFEDF--...............--EEIG-V.STRNKEG.E.T.PGKVMDIVT----------------------------..........-----------------------------------------givrnadvpqaklneivskvk...............................
A5ULZ4_METS3/1-143              ....migrcthvvdcratggmgkggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEC---GAEVLAVAMSPGRRHITKPVCEITFGLRESNVL..T..ST..MVLNAGAGvphd.....apasgGTLFGLTDKEVEQMSNFKLLVIHLGGVKNHLIYKARLILRNVN.KPcIIICESPVDC-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
Q64AP9_9ARCH/2-209              ....avgretqmlacrkgqglglgggiaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAKA--WKNDVVAVAMSPGTRHVPKPVCEITTELRGKGVS..T..GV..LVLNAGNGtprda...prtgghGSIFGLEQKEIDIIGGHKLAVLHHGNVKEHFIYKVRLELKKIP.ICaIILCQSPVEFVEFEQigvstrnkecetpgkVVGIVSGI.VRRESVP.Q.-.-DKLDEIVSKVRMCLRE--------------------..........-----------------------------------------ieeseekrdsta........................................
Q64BI9_9ARCH/1-131              ....mfgretqvidcregmglgrggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTLSET--GRPDVIAIAMSPGRRHITKPVCEITHGLRREGIQ..V..SV..LVLEAGAGipdegpsdkmakgyGPKFGLTQKEIEQIARHRVALIHLGNIDSHVIYKTKYVL----.--.---------------...............--------.-------.-.-.-------------------------------------..........-----------------------------------------r...................................................
G6FIP5_9EURY/2-151              ....pmgrvtqvvdcretmgmgkgggiaq-.-----------------------....---------.........--.........-.........-----------------------RGTISEC--RYPDVIVVGMSPGRRHVTKPVCDITSALRQQGVE..YsiST..LVLNAGSGvppdaa.niggavlGAYFGLTEKEIGQIEKHRVAILHHGNVRSHVVHKVRFILQACD.IKaIVVSQAPVDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
Q64A15_9ARCH/23-204             .........................giaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAKA--WKNDVVAVAMSPGTRHVPKPVCEITTELRGKGLS..T..GV..LVLNAGNGtprda...prtgghGSIFGLEQKEIDIIGGHKLAVLHHGNVKEHFIYKVRLELKKIP.ISaIILCQSPVEFEEFEQigvstrnkecetpgkVVGIVSGI.VRRESVP.Q.-.-DKLDEIVSKVR-------------------------..........-----------------------------------------mclreieeseek........................................
E3GWV5_METFV/1-269              .............................M.YETLIYKGGVHKSEEIKELVEDL....GGFVLQENV.........IQ.........M.........DLILTLAVPIKDVKKVEEKAKELLGKIRPAPMVGSEIAVVSPTLARHHLPHSACDIAEYLRRHGAK..T..NM..IGLARGAG..............KTISRISEDEKALINEHDLAIFAMGSFKECIEN-KTHLFSDID.VP.VVVTGAPKIENLPGAd.............aYVSGFGRI.PRRLKRG.E.N.IRALRKLVKVVENLLDKKREEISLDPPLVPPIVVKKE..........IEYQVPEVKEVYSPTPVTLQLDGVRVKLDYDEYHEKIGYVE....................................................
F6BE95_METIK/25-194             ...........................aq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEA--LRNDVVVVAMSPGRRHITKPVCEITYGIREAGIQ..T..SV..LVLDAGSGiphda....phgslGSTFGLKPEEAAQINRHKLCVVHFGNVINHVVYKARLLLRYVE.IPtIVVCQCPVDM-----...............--------.-------.-.-.--------EDFAKVGVKTLNVMPVEP--QTKGMIVDI..........VTGVVRGE------------------SCPQTKI--------deiiekik............................................
F7XL12_METZD/26-142             ............................r-.-----------------------....---------.........--.........-.........------------------------GTISEA--GSSDVIAVAMSPGRRHITKPVCELTYGMRKENIQ..V..SV..LVLQAGSGvpd.......vemtSGSFGISPEEIEQIARHKLAVIHVGNIPDHIMKKVREILSYVD.IPaIVVCQPPVDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
G7WN56_METH6/25-227             ............................q-.-----------------------....---------.........--.........-.........-----------------------RGTLSEA--SRPDVIAIAMSPGRRHITKPVCEITYGLRREGVQ..T..SV..LVLEAGAGvpdsfp..saskgfGPTFGLSPKEIEQIERHKIAVIHLGNIRSHVVYKAKEVLALAE.VPaVIVCQSPVDF--EDF..............aKVGVKTRL.VMPPRNKvE.T.LGTVVEIVYGVTRGATCQRAKLN--------------..........-----------------------------------------qlakvlnhhlarmereerkrreeeempeaerkarakk...............
F6D2L3_METSW/1-85               .............................M.YTIIFFCGGFYRFDELVEFIEDV....GGIILREDH.........FQ.........VsrgdyflaeEIRVILILPKDEIKSLKSIAKDIKGRIEDI------------------------------------..-..--..--------..............-------------------------------------------.--.---------------...............--------.-------.-.-.-------------------------------------..........-----------------------------------------kiedsqkrvm..........................................
A3CT48_METMJ/26-151             ............................q-.-----------------------....---------.........--.........-.........-----------------------RGTISET--RSPDVIVIGMSPGRRHVTKPVCDITSGLRREGAE..F..SVttLVLNAGSGvpadsp..vaghvlGAYFGLTEKEIAQIEQHKVAILHHGNVRSHVVQKVRFILEHTD.IRaIVVSQVPIDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------edl.................................................
D5VQV0_METIM/1-146              ...mpvgrfeqiidcravmglaeggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTLAEA--LKNDVVVVAMSPGRRHITKPVCEITYGIREVGIQ..T..SV..LVLNAGSGipads....prgslGSTFGIKPEEAKQINRHKLCIVHFGNVISHIVYKAALFLKYVE.IPtIIVCQAPVDME----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------d...................................................
E3GZA3_METFV/1-82               .............................M.YELVLFTGGVYKYDEFEEFIEDI....GGLILRQDKfevhrgiyfLR.........E.........EIKALTLVPECEIDKVKKFAKNLKGEIETI------------------------------------..-..--..--------..............-------------------------------------------.--.---------------...............--------.-------.-.-.-------------------------------------..........-----------------------------------------dvedevk.............................................
A6VJ56_METM7/1-266              .............................M.YEIIRYEGGVYKNNILKEWIEDI....GGFIIQEHV.........MQ.........L.........DVYMTIAIPHNEIENFKEEAKQYKGKIVETPLAGIEIAIVSPSLSRHHLPHIACDVSEYVRKFGAK..P..NM..IGLAHGAG..............KSISQIHEKEKRLIQEHDIAIYVMGNFESCILD-KTHLFK-ID.LP.LVVTGGPETLDIPYT...............YVGDLGRR.AQRLRKG.E.E.IRALRRMIDEVTKKINDKRLELSYDPPIIPPVVLKDE..........IEKKIDEVRGLLAPMPIVTQLDGLRIKMDYDRNHEEIENVK....................................................
MCRC_METBF/26-144               ............................q-.-----------------------....---------.........--.........-.........-----------------------RGTLSEA--GRAEVVAIAMSPGQRHITKPVCEITYGMRKENIQ..V..SV..LVLYSGSGipe.......sgmrTGSFVLSPVEVAQIEMHKLAVIHLGNIKDHVVRKTREILSQAN.IPaIVVSQIPVDFE----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------df..................................................
E1RDX6_METP4/1-200              ...mpigrvtqvvdcresmgmgkggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTISEC--RYPDIIVVGMSPGRRHVTKPVCDITSGLRREGVEfsV..ST..LVLNAGSGvpsdap.giagsvlGAYFGLNAKEISQIEQHKVAILHHGNVRSHVVEKVRFILQHCE.INaILVSQAPVDY--ED-...............-LAKVGVKtAYVMPDE.K.N.IRTKGKVV---------------------------A-..........-----------------------------------------ivsgvtrgqtptrenlaevisav.............................
H1KXL7_9EURY/25-194             ...........................aq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEA--LRNDVVVVAMSPGRRHITKPVCEITYGIREVGIQ..T..SV..LVLDAGSGiphda....phgslGSTFGLKPEEAAQINRHKLCVVHFGNVVNHVVYKARLLLRYVE.IPtIVVCQCPVDM-----...............--------.-------.-.-.--------EDFAKVGIKTLNVMPVEP--QTKGMIVDI..........VTGVVRGE------------------SCPQTKI--------deiiekik............................................
A6US32_METVS/1-276              .............................M.YQVIRYEGGVYKNNVLKEWIEDT....GGFIIQEHV.........MQ.........L.........DVYMTVAIPGSEIENFREEAKKYKGKIVETPLAGIEIAVVSPSLSRHHLPHIACDVSEYVRKFGAK..P..NM..IGLAHGAG..............KNISQLREKEKRLIQEHDIAIYVMGNFESCIKD-KIHLFN-VD.VP.LVVTGGPEKIDIPYT...............YVGNLGRR.SHRLRHG.E.E.IRALRQMIDEVTKKIADKRAELSYDPPIIPPVVVKDEiekkvvvkdeIEKKVEEVRGLLAPMPIVTQLDGLRIKMDYDRNFEEIENLK....................................................
Q2NI35_METST/29-156             ............................r-.-----------------------....---------.........--.........-.........------------------------GTYAQC---GDELLAVAMSPGRRHITKPVCEITFALRESNIQ..T..ST..LVLNAGSGvpkdt....psgggQGLFGVTPKEISQMSRHNIVLFHFGGVKNHIIYKAKHALKHIN.KPvIIIAQYPLDFE----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------dfakigvntv..........................................
D7EBD8_METEZ/1-275              .........................mgvv-.LEPYIYEGGMYKHGLILELLEDL....GGYLVQKTP.........AG.........S.........EVTLVMLIPKEDVHLVQDLAKKLLGTLTKAPLTGTEIAVVSPTLASHHLPHSACDVAEYLRRGGSN..T..NM..IGLARGMG..............RRVSLSEDYERKLINEHDVAVFSFGVFSDCIINKKPKLFKGIK.VP.IVATGGP-ELNTEDVpg..........admYVGGIGRI.AHRMRKE.G.E.LNSLDVLNEKVGEMIENKREKLAKDPLSVIPARVMQE..........IERQISDIQNVLSPAPITLQLDGLRIKLPYEDYHKNIENL-e...................................................
F0T7K3_METSL/1-90               .............................M.YKIFVFNGGVYRFEELEEFVEDS....GGLILRRDDfhvsrgvyfIS.........Q.........EVHVVIIMPEEAVHDLNLLATEIKGDIELI------------------------------------..-..--..--------..............-------------------------------------------.--.---------------...............--------.-------.-.-.-------------------------------------..........-----------------------------------------evdyedkinlvsllp.....................................
A0B6L3_METTP/25-195             ............................q-.-----------------------....---------.........--.........-.........-----------------------RGTLSEA--ARPDVIAIAMSPGRRHITKPVCEITYGLRREGIQ..T..SV..LVLEAGTGvpdsfp..qasrgyGPTFGLTPKEIEQIQRHKIAVIHLGNVKSHVIYKTRDILAYVD.IPaVVVSQCPVDFE----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------dfakegvktrvvmppkskqatmgtvvdivtgvtrgatcgrsklntlakv...
G0H350_METMI/1-266              .............................M.YQIIRYEGGVYKNNILKEWIEDV....GGFIIQEHV.........MQ.........L.........DVYMTIAIPQNEIENFKEEAKKYKGKIVETPLAGIEIAIVSPSLSRHHLPHIACDVSEYVRKFGAK..P..NM..IGLAHGAG..............KSISEIREKEKRLIQEHDIAIYVMGNFESCILD-KTHLFK-VD.IP.LVVTGGPETLDIPYT...............YVGNLGRR.AQRLRKG.E.E.IRALRQMIDEVTKKINDKRMELSYDPPIIPPVVLKDE..........IEKRIDEVRGILAPMPIVTQLDGLRIKMDYDRNHKEIENVK....................................................
Q8TXS7_METKA/1-275              .......................mgvasv-.FETVIYEGGVYKADEMRDLVEDL....GGFVLSEHQ.........MQ.........L.........EVHMVLAVPVDDLDVIERKAEELLGEIRRMPLAGTEIAVVGMSLARHHMPHPVCDIAEYLRRHGAK..S..NV..IGLARGYG..............RELAQLRTREKRLLEEHDLVIFVVGNFKDCIEKYKLPLVRRIErVP.VVVVGGPEEIDADDV..............vYVGGIGRK.PYRFRKG.R.E.ITKLDEIVDVVSKIIEERRQELAEDPPVVPPMVVKDR..........INRELKIEERFTSPMPITLQLDGLRVKAPYDEWADRVAEVE....................................................
A6UWA9_META3/1-266              .............................M.YGIVRYEGGVYKNNIFKEWIEDI....GGFIIQEHV.........MQ.........L.........DVYMTLAIPQNEIENLKIESKKYKGKVVETPLAGTEIAIVAPSLSRHHLPHTACDVSEYVRRFGAK..P..NM..IGLSRGFG..............KKTSSIREAEKRLIEEHDIAIYVMGNFKSCLLD-KTHLFD-VD.IP.VVITGAPETLDIEQP...............YIGNLGRR.SQRLRHS.E.E.RQALKKMIEKTTELIDKRREELSFDAPIIPPVVLKDE..........LEKSVEEIFNVLSPMPITTQLDGLRIKLPYDACHEKIENVK....................................................
Q12UT6_METBU/1-275              .........................maav-.LEPYIYEGGIHKHSLILELLEDL....GGYLVQKTP.........AS.........T.........EITLVMLIPKKDVHLVEDVCIKLLGKLTSAPLTGTEVAVVSPTLASHHLPHSACDIAEYLRRGGAN..T..NM..IGLARGMG..............RRVALSADYERRLINEHDVAVFSFGIFKDCIINKKPKLFEGIE.IP.IVVTGGP-DIRTEEIsg..........adiYVGGIGRV.AHRMRKG.P.E.LDAMDVLNEKVGEIVNLKRESIAKDPLAVLPARLMKE..........VQEQVPVILSVLTPAPITLQLDGMRIKLPYDRYRDAVGNIE....................................................
MCRC_METTH/1-192                ...........................mi-.----------GKCTHVVDCRETMgmgeGGGIAQR--.........--.........-.........------------------------GTFAQC---GSEVLAVAMSPGRRHITKPVCEITFALREANIM..T..ST..IVLNAGAGvpqda....psagaGSLFGLTPAEVEQMKRHKLLVVHLGGVKNHITYKARLILRNVD.RPcIIICEYPVDF-----...............--------.-------.-.-.--------EDFAKIGVRTRAVMPDEP--KTKGTIVDI..........VSGVIRGE------------------TCPQEKLDEIIRKV-k...................................................
A4FZ81_METM5/1-266              .............................M.YEIIRYEGGVYKNNILKEWIEDV....GGFVIQEHV.........MQ.........L.........DVYMTIAIPHNEIENFKEEAKSYKGKIVETPLAGIEIAIVSPSLSRHHLPHIACDVSEYVRKFGAK..P..NM..IGLAHGAG..............KSISQITEREKRLIQEHDIAIYVMGNFESCILD-KTHLFK-ID.LP.LVVTGGPETLDIPYT...............YVGDLGRR.AQRLRKG.E.E.IRALRRMIDEVTKKINDKRLELSYDPPIIPPVVLKDE..........IEKRIDEVRGLLAPMPIVTQLDGLRIKMDYDRSHEEIENVK....................................................
D1YXG5_METPS/1-270              .............................M.-EPFIWTGGLYKHEEFEELVEDM....GGYILQKNI.........LQ.........S.........DVIMVILVPNADIPVIEAKNRELLGKLVKAPLAGAEVAVITPTLAYQHLPHLACDVAEYLRRAGSK..T..NM..IGLARGVG..............KRVAQLTAKEIDLINEHDAALFLYGNFKHCIIE-KTKLFRDIE.VP.IVVTGGP-ELKTSEVpg..........ceaYISGLGRM.MHRLRQK.E.E.TESMDRIVNAIGKVLDERRSELDKDQLSVSPPRLKAE..........IEKQVPDIQDVISPTPVTLNLNGARIKLSYNDYRDVIANI-r...................................................
A7IB43_METB6/1-276              ...........................mi-.LVPVTYKGGVYRHNEIIDLIEDL....GGYIVQKHM.........IA.........Q.........EVVLQCFVPKEDVELIRAIGKPLAGEVTDSPLVGTEIAIVSMSLEIHHLPHPSCDIAEYVRRLGAK..S..NM..VGMARGVG..............KRIAGINDEERDVINEHDIAVYLMGNFEHCIEKKMPILLRGIE.VP.VVVCGGPDKEVLERIvep........kvdgYVGNMGRF.MHRTKES.E.E.LSRLDEVIEEVTRVLAKKREAIAKDPLSVAPARLMDV..........IKEKVPAILEVTSPTPLTVQMAGLRVKLPYDTFAGVLKK--te..................................................
H1KYG2_9EURY/1-266              .............................M.YEIVRYEGGVYKNNILKEWIEDI....GGFVIQEHV.........MQ.........L.........DVYMTVALPQSEIEAFKEEAKKYKGKVVETPLAGIEIAVVAPSLSRHHLPHTACDISEYVRRFGAK..P..NM..IGLAHGAG..............KNISRISEREKKLIEEHDVAIYVMGNFENCIKD-KTHLFD-VD.IP.VVVTGGPEELDIPYP...............YVGNLGRR.AHRLRHG.E.E.TRALRKMVDVVTDLINERRRELSYDPPIVPPVVVKDE..........IEKRVEEVFNILSPMPIVTQLDGLRIKMDYDKYKDKIANVK....................................................
C9RHQ2_METVM/1-266              .............................M.YEIVRYEGGVYKNNIFKEWIEDI....GGFIIQEHI.........MQ.........L.........DVYMTLAVPQNELENLREEAKKYKGKIIETPLAGTEIAVVAPSLSRHHLPHTACDISEYLRRFGAK..P..NM..IGLARGVG..............RDIAQLREKEKRLIEEHDLAVYVMGNFEDCIKN-KTHLFD-VD.IP.VVITGGPQTLDIPYP...............YVGDLGRR.SHRLRHG.E.E.IRALRKMVEVITELINERRRELSYDPPIVPPVVVKDE..........IEKQVDEVYSILSPMPIVTQLDGLRVKLDYDKYAEKISNVK....................................................
D3S8N3_METSF/1-266              .............................M.YEIVRYEGGVYKNNIFKEWIEDI....GGFVIQEHV.........MQ.........L.........DVYMTLAIPQNELENIKEEAKKYKGKIIETPLAGTEIAVVAPSLSRHHLPHTACDISEYLRRFGAK..P..NM..IGLARGVG..............RDIAQLREKEKRLIEEHDLAVYVMGNFEDCIKN-KTHLFD-VD.IP.VVVTGGPEKIDIPYP...............YVGNLGRR.SHRLRHG.E.E.IRALRKMVDVITELINERRRELSYDPPIVPPVVVKDE..........IEKQVEEVYSILSPMPIVTQLDGLRVKLDYDKHADKIREVK....................................................
Y094_METJA/5-270                .............................M.YEIVRYEGGVYKNNIFKEWIEDI....GGFVIQEHV.........MQ.........L.........DVYMTLAIPQNELENIKEEAKKYKGKIIETPLAGTEIAVVAPSLSRHHLPHTACDISEYLRRFGAK..P..NM..IGLARGVG..............RDIAQLREKERRLIEEHDLAVYVMGNFEDCIKN-KTHLFD-VD.IP.VVVTGGPEKIDIPYP...............YVGNLGRR.SHRLRHG.E.E.IRALRKMVEVITELINERRRELSYDPPIVPPVVVKDE..........IEKQVEEVYSILSPMPIVTQLDGLRVKLDYDKYADKIREVK....................................................
Q49603_9EURY/18-134             ......................kggslaq-.-----------------------....---------.........--.........-.........-----------------------RGTIAET--EITEVVAVAMSPGSRHITKPVCEITYALREAGIG..S..GV..PAEAPVQT..............GATMGIEPEEIERINRHEVAVIHLGNVKQHIVWKARLILKHCD.VPaVIVCQTPVDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
F7XKF1_METZD/1-275              .........................msrv-.LEPYIYEGGIHKHGLMLELLEDI....GGYLVQKTP.........AA.........T.........EVTLIMFIPKEDVPLVQDLAGNLLGKLTKAPLTGVEIAVVSPTLAYHHLPHSACDIAEHLRRDGAN..T..NM..IGLARGMG..............RRVAMLNDYERKLINEHDIALYSFGIFSDCIMNKKTSLFEGIE.IP.IVVTGGP-ELSTEDVsg..........adlYIGNIGRI.PHRMRKS.E.E.LNALDVMNKKVGELVDRVREDLSKDPPVVLAARVMKE..........IQDQVPDISNVLTPSPITLQLNGLRVKLPYDQYHEKIGNIE....................................................
A3CX85_METMJ/1-277              ..........................mtt-.LVPVTYKGGVYRHDEIMDLIDDL....GGYIVQKHV.........MA.........Q.........DVVLQSFVPRDDIEMIRRIAKPLAGEVVEAPLVGTEIAVVSPSLEIHHLPHISCDIAEYLRRSGAK..T..NM..VGLARGFG..............KRIANLNDEERDVINEHDLAVYALGNFEECIRQKFPAIRREIH.VP.IVVTGAPDRETLMRAidp........pvegYVGGIGRI.MHRFKRP.E.E.LGKLDELVDEISRVLDARRDALAKDPLSVFPPRLMAI..........IEEQIHEVSLLTHPTPVTAQMEGLRVKLPYDSYADDVRSL-e...................................................
A2STS1_METLZ/2-202              .....plgrvtqlvdcrqsmgmgkggsla-.-----------------------....---------.........--.........-.........----------------------QRGTISEC--KNPDVIIVGMSPGRRHITKPVCDITSALRQQGIEysV..ST..LVLNAGSGvppdad..iggvslGSNFGILDREIEQIERHKVAVLHHGNIRSHVVHKSRKILQECN.VNaVVVCQAPVDYE--D-...............--------.-------.-.-.-------------------------------------..........-----------------------------------------lakagvktayvmpkpddirtkgtvmglvtgitrgqtpsrvamsdvihevlri
D3E052_METRM/26-193             ............................r-.-----------------------....---------.........--.........-.........------------------------GTFAEC---GSDVLAVAMSPGRRHITKPVCEITFGLREANLL..T..ST..MILDAGSGvphda....paggaGNAFGLTDKEVEQMQKFKVIVVHLGGVRNHITYKARLILRNVN.KPcVIICEYPVDF--ED-...............-FAKIGVK.TAKVM-P.D.E.VKTEGKIMNIVSGVIRG--------------------..........-----------------------------------------qtvsqekldeiirkvrl...................................
D1JFS8_9ARCH/2-210              ...mavgretqmlacrkgqglglgggiaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAKA--WKNDVVAVAMSPGTRHVPKPVCEITTELRGKGVS..T..GV..LVLNAGNGtprda...prtgghGSIFGLEQKEIDIIGGHKLAVLHHGNVKEHFIYKVRLELKKIP.ICaIILCQSPVTFEEFEQvgvstrnkecetpgkVVGIVSGI.VRRESVP.Q.-.-DKLDEIVSKVRMCLRE--------------------..........-----------------------------------------ieeseekrdsta........................................
A6VHE5_METM7/26-147             ............................q-.-----------------------....---------.........--.........-.........-----------------------RGTFAEG--LRNDVVVVAMSPGRRHITKPVCEITYGIREAGIQ..T..SV..LVLDAGAGipsda....pqgslGSTFGLKPEEAKQVNRHKLCVIHFGNVKSHIIYKARLFLKYVD.IPtIIVCQAPVDME----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------df..................................................
Q6VUA3_9ARCH/25-149             ............................q-.-----------------------....---------.........--.........-.........-----------------------RGTLSET--GRPDVIAIAMSPGRRHITKPVCEITHGLRREGIQ..V..SV..LVLEAGAGvpeegpsdrmakgyGPKFGLTQKEIEQISRHRVALIHLGNIDSHVIYKTKYVLKYVD.IPaVIACQNPVDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
Q2FSN2_METHJ/2-151              .....pigrvtqvvdcresagmgkggala-.-----------------------....---------.........--.........-.........----------------------QRGTISEC--RYPDVIIIGMSPGRRHVTKPVCDITSALRAQGVE..YsiST..MILNAGSGippdap.ksaghvlGAYFGLNEKEIIQVNRHKVAVLHHGNVRSHIVHKVRSILKDCD.IPaVVVCQAPVDY-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
Q64E09_9ARCH/2-193              ....vvgrktqlvacrkgqalglgggiaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAKA--RQNDVIALAMSPGYRHVPKPVCQITTELRGRGIN..V..GE..IVLNAGDGtpads...pssgghGVAFGLQANEMEIIGMHKLALLNHGNVKAHFIYKVRFELRKVA.IPaIVLCQCPVTFEDF--...............--EEIG-V.STRNKEG.E.T.PGKVMEIVTGI--------------------------..........-----------------------------------------vrnadvpqaklneivskvkm................................
D3E057_METRM/1-271              .............................M.YETLTFTGGIHKSEELKELIEDL....GGFVLQSNI.........LQ.........M.........ELVLNMAVPIDDVKIIEDKANELLGELSVAPMAGSEIAIVSPTLARHHLPHAACDISEYLRRYGAK..D..NM..IGLARGHG..............KGTAGISETEKALIEEHDIAIFALGSFKQCIVD-KAYLYNDID.IP.VIVTGAP-EIDLEELpg..........vdaYVPGLGRI.PRRLKRG.E.N.IRALKHLVQTIEDLLEKRKKELAQDPPIVPSILVKNE..........IENQVPAIEGVFSPTPVTSQLSGLRVKLDYDNYHEEIENV-v...................................................
D1JIA4_9ARCH/1-263              .............................M.YKIMMFEGGVYKFYELKELVGDL....GGFILQESV.........MQ.........T.........ETMMHLAFPEEDEQEIRNKIKELGGKFKELPLAGTEIIIVVPSLGKHHAVDPMCDIAEFLRRSGAI..T..NM..MGLARGVG..............RRIAQMTTQEKKIIEEFDAAVFIFGTFEECIEE-KVKLCKSID.IP.YIIVGGPQDMELEH-...............YVGGVGRK.TARMRNK.D.E.IDRLYDMASELERALAEKRLDIEEDPIAASPLFIKDM..........IEKTI--LPKTGEELPNIIQLDGLRVKMEEEDI-EKIKEIE....................................................
Q8TIZ7_METAC/1-275              ..........................mvv-.LLPYLYTGGVHKHGLLIELMEDL....GGYIIQKVV.........TG.........T.........EVNLIMLIPEKDLDIVKKLAGELLGVLIEAPLTGVEIAVVSPTLASHHLPHSACDVAEYLRHPGAN..T..NM..IGLARGMG..............RRVSLSMDYERKLINEHDIAVFSFGSFSDCITKKKPKLFEGIE.IP.IAVTGGPTELKTEDVpg..........adlYVGNIGRV.SHRLRRT.E.E.IEALDKLNEGVSKIASDIRKQQAKDPLAVLPARVMKE..........IENQVPEIQRVLSPAPLTLQLDGLRVKLPYDEFHEKIEKL-e...................................................
Q0W8W5_UNCMA/1-270              .............................M.-EPLIFQGGIYKHEQMIELVEDL....GGYILQKNV.........LQ.........L.........DVIVVMLVPNADLPLIEAKAKELLGKLTKAPLAGAEIAVVTPTLAYQHLPHLACDIAEYLRRAGSK..T..NM..IGLARGVG..............KRVAQLKATEIDLINEHDCAVFTYGNFRECIKE-KTKLFRDIE.VP.IVVTGGP-NMDVVEVpg..........cvaYIGGLGRV.MHRTRQK.D.E.LAILDRLVDATGKVLDERRAELDKDPLSVSPPRVMHE..........IEKQIPDIPESLAPTPITLQLNGCRIKVPYDEYAERILNVK....................................................
B8GJ60_METPE/1-276              ...........................mi-.LVPVTYRGGLYRHDEIVDLIEDL....GGYVIQKHL.........IA.........T.........EVVLLALVPKDDIELIRKIGKPLMGELTESPLVGTEIAIVTPSLEIHHLPHPACDIAEYVRRLGAK..S..NM..VGLARGFG..............KRIAMLNDEERDVINEHDIAVYLLGNFETCIKKKMPVLIRGIT.VP.IILTGRPSKETLKRItdp........pvagYVGEIGRF.MHRTREA.D.E.LGKLDTVIAEIIHVLDKRRADIAKDPLSISPARLMAV..........INEKVPEIREVTSPTPITVQIAALRVKLPYDMFAGRLREL-e...................................................
F0T8Q6_METSL/1-271              .............................M.YETLTYTGGIHKHEEMTELIEDL....GGFVLQENI.........SQ.........M.........DLVLTLAVPIEDIDKIEDKAKELLGSIKIAPMAGTEIAVVSPTLARQHLPHSACDISEYLRRYGAK..D..NM..IGLSRGAG..............KGISRISEDEKKLIEEHDLAVFALGSFRECITN-KTHLFEDIE.IP.VVVTGAP-DIDLDDIpg..........adaYVSGLGRI.PRRLKRG.E.N.IRALKKLVEVIETIFDEKRREILLDPPIVPPVLVKRE..........IENQVEAIAEVYSPLPVVSQLMGVRVKLDYDEYHQEIEDV-m...................................................
MCRC_METTM/1-192                ...........................mi-.----------GKCTHVVDCRETMgmgeGGGIAQR--.........--.........-.........------------------------GTFAQC---GSEVLAVAMSPGRRHITKPVCEITFALREANIM..T..ST..LVLNAGAGvpqda....psagaGSLFGLTPAEVEQMKRHRLLVVHLGGVKNHITYKARLILRNVD.RPcIVICEYPVDF-----...............--------.-------.-.-.--------EDFAKIGVKTRVVMPDEP--KTKGTIVDI..........VSGVIRGE------------------TCPQEKLDEIIRKV-k...................................................
Q8THG9_METAC/26-143             ............................q-.-----------------------....---------.........--.........-.........-----------------------RGTLSEA--GRADVVAIAMSPGQRHITKPVCEITYGMRRENIQ..V..SV..LVLYSGSGipe.......sgmrTGSFVLSPVEVAQIEMHKLAVIHLGNIKDHVIRKTREILSQAD.IPaIVVSQIPVDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
H8I4A9_METCZ/1-198              ....mpidretqvvdcresmgldkgggla-.-----------------------....-----Q---.........--.........-.........-----------------------RGTLSET--GRPDVIAIAMTPGNRHITKPVCEITHGLRREGIQ..V..SV..LVLYSGGGvpsdak..daaigrGPKFGMTEKEIEQINRHKLALIHLGNVKSHVIYKARDILRFVS.IPaIIVCQAPVDF--ED-...............-FARIGVK.-------.-.-.-------------------------------------..........-----------------------------------------trvvnpepdkvetqgtiveivtgitrgqtcpraklneivkdii.........
G9BY96_9ARCH/1-151              ...mpigrvtqvvdcresmgmgkggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTISEA--RSPDVIVIGMSPGRRHVTKPVCDITSGLRREGAQ..F..SVttLILNAGSGvpadsp..vaghvlGAYFGLTEKEIVQIEQHKVAILHHGNVRSHVVQKVRFILEHAD.IKaIVVSQVPIDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------edl.................................................
B8GE91_METPE/26-151             ............................q-.-----------------------....---------.........--.........-.........-----------------------RGTISEC--RFPDVIVVGMSPGRRHVTKPVCDITSALRQQGVE..YsiST..LILNAGSGvppdap.siaggvlGAYFGLTEKEIRQIERHKVAILHHGNVRSHVVQKVRYILQYCN.IPaVVVSQAPIDF-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
C9REL3_METVM/1-146              ...mpvgrreqivdcrsvmglgeggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEA--LRNDVVVVAMSPGRRHITKPVCEITYGIREAGIQ..T..SV..LVLNAGSGiphda....prgalGSTFGIKPEEAEQINRHKLCVVHFGNVISHIVYKAGLLLKYVE.IPtIIVCQAPVDME----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------d...................................................
E1RIS0_METP4/1-277              ...........................mv-.LVPITYKGGVFRHDIIIDLIDDL....GGYVVQKHM.........IA.........Q.........EVILQSLVPREDIELIRKTGRPLGGEVIEAPLVGTEIAVVTPSLEIHHLPHTSCDAAEYLRRAGAK..T..NM..IGLARGFG..............KRIANLNIEERDVINEHDCAVFLLGNFESCIKYKLPALRRGIR.VP.IILTGGPDTKKLKKLadp........pvegYVGGIGRI.GHRMQKQ.EgE.IEFLDRLVDEVSGVLEKRREEIAKDPLSISPARLMAA..........IDDELGLSETSTHPTPVTVQIAGLRVKIPYDNFSGMIGDI-e...................................................
B9AF04_METSM/1-147              mtfkmigrcthvvdcratggmgkggglaq-.-----------------------....---------.........--.........-.........-----------------------RGTFAEC---GAEVLAVAMSPGRRHITKPVCEITFGLRESNVL..T..ST..MVLNAGAGvphd.....apasgGTLFGLTDKEVEQMSNFKLLVIHLGGVKNHLIYKARLILRNVN.KPcIIICESPVDC-----...............--------.-------.-.-.-------------------------------------..........-----------------------------------------ed..................................................
F8AMU2_METOI/27-194             ............................r-.-----------------------....---------.........--.........-.........------------------------GTFAEG--LKNDVVVVAMSPGRRHITKPVCEITYGIREAGIQ..T..SV..LVLDAGTGiphda....phgslGSTFGLKPKEAEQVNRHKLCVIHFGNVKSHIVYKARLFLRYVH.IPtIVVCQTPVDM-----...............--------.-------.-.-.--------EDFAKVGVKTKEVMPIEP--KTGGMIVDI..........ITGVVRGESAPQSK---------------------------ideviekik...........................................
F4BVZ9_METCG/1-271              .............................M.LEPVMFTGGLYKHDLVLELVEDL....GGYILQKNV.........TQ.........T.........EIILLLLVPSEDMNALEILSRDLRGELVRAPLAGTEVAVVTPTLAIHHLPHVACDIAEYLRRHGSK..T..NM..IGMARGVG..............REIAQINEYETALINEHDAAVFIFGNFEDCIKK-KEDLYRNIG.VP.VIITGGP-KIDPEELpy..........afgYVPSIGRM.AHRTRKA.T.E.IGSLDNIVEMVGRALDKTREAIAKDPLTTSPPRVMDA..........VREQVPEVEFSYSPLPIALNLTGVRVKLPYAGYRDKVAAV-t...................................................
#=GC seq_cons                   ........................................................................................................................+GplsEs..tts-lslVu.S.uR+Hls+ssC-IophLRctGhp..s..sh..lsLstGsG..............tshhslptcEhc.IpcHclAVhphGNhcspIl.Ktphlhc.lc.lP.llVstuP.-h.................................................t...............................................................................t...................................................
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