GenomeNet

Database: Pfam
Entry: MCR_alpha
LinkDB: MCR_alpha
Original site: MCR_alpha 
#=GF ID   MCR_alpha
#=GF AC   PF02249.16
#=GF DE   Methyl-coenzyme M reductase alpha subunit, C-terminal domain
#=GF AU   Mian N, Bateman A, Griffiths-Jones SR
#=GF SE   Pfam-B_2706 (release 5.2)
#=GF GA   25.00 25.00;
#=GF TC   64.70 63.80;
#=GF NC   24.80 20.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   9367957
#=GF RT   Crystal structure of methyl-coenzyme M reductase: the key enzyme
#=GF RT   of biological methane formation 
#=GF RA   Ermler U, Grabarse W, Shima S, Goubeaud M, Thauer RK; 
#=GF RL   Science 1997;278:1457-1462.
#=GF DR   INTERPRO; IPR009047;
#=GF DR   SCOP; 1mro; fa;
#=GF CC   Methyl-coenzyme M reductase (MCR) is the enzyme responsible for 
#=GF CC   microbial formation of methane. It is a hexamer composed of 2
#=GF CC   alpha (this family), 2 beta (Pfam:PF02241), and 2 gamma
#=GF CC   (Pfam:PF02240) subunits with two identical nickel porphinoid
#=GF CC   active sites [1]. The C-terminal domain is comprised of an
#=GF CC   all-alpha multi-helical bundle.
#=GF SQ   79
#=GS A0A0P9E1V1_9ARCH/368-495  AC A0A0P9E1V1.1
#=GS E1RJD5_METP4/326-459      AC E1RJD5.1
#=GS F0TCV5_METLA/317-441      AC F0TCV5.1
#=GS A0A126R0Q7_9EURY/323-447  AC A0A126R0Q7.1
#=GS A7I5T9_METB6/326-452      AC A7I5T9.1
#=GS A0A0W7TIP2_9EURY/319-446  AC A0A0W7TIP2.1
#=GS Q0W339_METAR/322-447      AC Q0W339.1
#=GS F4BXY1_METCG/324-450      AC F4BXY1.1
#=GS A2SSD1_METLZ/326-459      AC A2SSD1.1
#=GS L0L0H0_METHD/330-462      AC L0L0H0.1
#=GS A5ULM9_METS3/318-442      AC A5ULM9.1
#=GS U6EF81_9EURY/317-441      AC U6EF81.1
#=GS A0A124G584_9EURY/326-459  AC A0A124G584.1
#=GS A6UWH2_META3/318-443      AC A6UWH2.1
#=GS J0RY59_9EURY/326-459      AC J0RY59.1
#=GS D5EAD6_METMS/332-464      AC D5EAD6.1
#=GS D3E050_METRM/315-441      AC D3E050.1
#=GS MCRA_METKA/319-444        AC Q49605.2
#=GS MCRA_METKA/319-444        DR PDB; 1E6V A; 319-444;
#=GS MCRA_METKA/319-444        DR PDB; 1E6V D; 319-444;
#=GS A0A0P8CBK4_9EURY/327-453  AC A0A0P8CBK4.1
#=GS M9SBG6_9EURY/319-446      AC M9SBG6.1
#=GS G7WN24_METH6/324-450      AC G7WN24.1
#=GS MCRX_METFV/319-444        AC Q49174.2
#=GS A0A139CTB8_9EURY/331-463  AC A0A139CTB8.1
#=GS I7KDB2_METBM/326-459      AC I7KDB2.1
#=GS L0HD22_METFS/328-461      AC L0HD22.1
#=GS M4YK22_9EURY/317-444      AC M4YK22.1
#=GS A2STR9_METLZ/326-459      AC A2STR9.1
#=GS A0A124G4P2_9EURY/1-123    AC A0A124G4P2.1
#=GS A0A166CWD2_9EURY/316-442  AC A0A166CWD2.1
#=GS A0A101DQI1_9EURY/217-342  AC A0A101DQI1.1
#=GS A0A0P9HYI1_9ARCH/370-498  AC A0A0P9HYI1.1
#=GS I7LMP5_METBM/326-459      AC I7LMP5.1
#=GS A0A166CHN2_9EURY/316-442  AC A0A166CHN2.1
#=GS A0A150J3N1_9EURY/320-446  AC A0A150J3N1.1
#=GS A0A0Q4BCJ2_9EURY/309-436  AC A0A0Q4BCJ2.1
#=GS A0A0E3NU58_9EURY/330-461  AC A0A0E3NU58.1
#=GS E1RDX4_METP4/326-459      AC E1RDX4.1
#=GS A0A166B5P3_9EURY/318-442  AC A0A166B5P3.1
#=GS K4MC35_9EURY/331-463      AC K4MC35.1
#=GS A0A166C196_9EURY/316-442  AC A0A166C196.1
#=GS A0B6N6_METTP/324-450      AC A0B6N6.1
#=GS MCRX_METJA/318-443        AC Q60391.1
#=GS MCRA_METTH/316-441        AC O27232.3
#=GS A3CT46_METMJ/326-459      AC A3CT46.1
#=GS F0T8R3_METLA/316-441      AC F0T8R3.1
#=GS Q6LWZ5_METMP/319-444      AC Q6LWZ5.1
#=GS A0A0Q1C669_9EURY/326-420  AC A0A0Q1C669.1
#=GS R9TAZ9_9EURY/316-442      AC R9TAZ9.1
#=GS Q8THH1_METAC/329-461      AC Q8THH1.1
#=GS F6D2D3_METPW/316-442      AC F6D2D3.1
#=GS A0A150J824_9EURY/320-446  AC A0A150J824.1
#=GS J0SAE9_9EURY/326-459      AC J0SAE9.1
#=GS A3CSG1_METMJ/326-459      AC A3CSG1.1
#=GS U6EEP1_9EURY/316-441      AC U6EEP1.1
#=GS E3GZ51_METFV/319-445      AC E3GZ51.1
#=GS F7XL13_METZD/331-463      AC F7XL13.1
#=GS A0A101DXX5_9EURY/331-457  AC A0A101DXX5.1
#=GS Q2FSN0_METHJ/325-458      AC Q2FSN0.1
#=GS MCRA_METJA/318-444        AC Q58256.2
#=GS A5ULZ2_METS3/316-442      AC A5ULZ2.1
#=GS Q8PXH8_METMA/329-461      AC Q8PXH8.1
#=GS B8GE93_METPE/325-451      AC B8GE93.1
#=GS D7E8X7_METEZ/332-464      AC D7E8X7.1
#=GS A0A059TIR1_9EURY/318-445  AC A0A059TIR1.1
#=GS A0A166A6T9_9EURY/316-442  AC A0A166A6T9.1
#=GS MCRA_METBF/329-461        AC P07962.3
#=GS MCRA_METBF/329-461        DR PDB; 1E6Y D; 4329-4461;
#=GS MCRA_METBF/329-461        DR PDB; 1E6Y A; 1329-1461;
#=GS D1YVW6_METPS/323-448      AC D1YVW6.1
#=GS A0A101IW49_9EURY/1-60     AC A0A101IW49.1
#=GS A0A0A7LF46_9EURY/319-446  AC A0A0A7LF46.1
#=GS MCRX_METTH/318-443        AC P21110.3
#=GS D7DUH5_METV3/319-444      AC D7DUH5.1
#=GS Q12TF8_METBU/331-463      AC Q12TF8.1
#=GS A0A120K0D9_9EURY/316-442  AC A0A120K0D9.1
#=GS Q2NHZ8_METST/318-443      AC Q2NHZ8.1
#=GS R9SLW2_9EURY/316-442      AC R9SLW2.1
#=GS A0A126R1N8_9EURY/315-441  AC A0A126R1N8.1
#=GS H1YXH9_9EURY/326-459      AC H1YXH9.1
#=GS L0HIJ7_METFS/327-453      AC L0HIJ7.1
#=GS D5VQU8_METIM/318-444      AC D5VQU8.1
A0A0P9E1V1_9ARCH/368-495             say---WFGFYMSGGIGFTNTTAGA.ALGEASETFQEELAELSNKYA.......ADID.....RVPP.RWDVVRFIVDMIIQYAMETYEKIPALTEFHWGGAHRISLIGSLGAGTAALLTGDSTMGL.WGsHYAIALAMKEGWLR-t
E1RJD5_METP4/326-459                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDEFTYYGMDYIGDKYnvdwknpSPSD.....KIKP.TQDIVNDIATEVCLNAMEQYEQFPTMMEDHFGGSQRAGVMAAACGLSTSIATGNSNAGL.NA.WYLCMLMHKDGWSRL.
F0TCV5_METLA/317-441                 ...DQIWLGSYMSGGVGFTQYATAA.YTDDILDDFLYYGKEYVEDKF.......-GLC.....GVKA.DADVVKDISSEITLYAMEQYE-IPALLEDHFGGSQRACVAAAAAGCSTAFATGNSNAGI.NG.WYLSQILHKEVHSRL.
A0A126R0Q7_9EURY/323-447             ...DQVWLGSYMSGGVGFTQYASAT.YTDDILDDFIYYGKDYVEKNY.......-GMC.....QAEA.NFDNVKDIATEVTIYGLEQYE-IPTLLEDHFGGSQRASVISAAAGCSVAFATGNSNAGV.NG.WYLSMIEHKEAHSRL.
A7I5T9_METB6/326-452                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDDYCYYGLDYVKKNH.......GGLG.....KAKL.TQEAVSDIASEVTLYGMEQYEQYPTALEDHFGGSQRASVLAAASGISASLGTFNSNAGL.NA.WYQSMLLHKEGWSRL.
A0A0W7TIP2_9EURY/319-446             ...DQIYLGGYMSGGVGFTQYASAA.YTDNILEDYVYHGIDVINDRY.......GGFC.....GIKPdDYDKQMKLGDEISSYALEMYERYPAVMETHFGGSQRATVTAASTGIVGAFATGVADNGL.NL.WYQSMLQHKERTGRL.
Q0W339_METAR/322-447                 ...DQIWLGSYMSGGVGFTQYATAA.YTDDILDDFCYYGYDYIKGKY.......-GIA.....KAKP.TMDVVNDIGTEVTLYGIEQYEKYPTTLEDHFGGSQRATVLSAAAGVTTSLATGNANAGL.SA.WYLSMYLHKEAWGRL.
F4BXY1_METCG/324-450                 ...DQIWLGSYMSGGVGFTQYATAA.YTNDVLDDFSYYGVDYANDKF.......GGFA.....KAPA.TIDVAKELATEVTLYGIEQYEAFPTLLEDHFGGSQRAAVLAAASGITSAIATGHSQIGL.AG.WYLSMLLHKEAWGRL.
A2SSD1_METLZ/326-459                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDDFVYSGMDYIHDKYkvdlknpNPND.....KVKA.TQEVVNDIATEVNLYGMEQYEQFPTMMEDHFGGSQRAAVLAAASGITTSIATGNSNAGL.NG.WYLSMLLHKDGWSRL.
L0L0H0_METHD/330-462                 ...DQIWLGSYMSGGVGFTQYATAA.YTNNILDDNLYYNVDYINDKYnga.akkGTDN.....KVKA.TLEVVKDIATESTLYGMENYEKYPTALEDHFGGSQRATVLSAAAGAATAIATGNGNAGL.SG.WYLSMYLHKEGHGRL.
A5ULM9_METS3/318-442                 ...DQVWLGSYMSGGVGFTQYASAT.YTDDILDDFVYYGLDYVEDNY.......-GLC.....QAEK.TMDVVRDISTEVTLYGLEQYE-IPTLLETHFGGSQRASVISAAAGCSTAFATANSNAGV.NG.WYLSMLLHKEGHSRL.
U6EF81_9EURY/317-441                 ...DQIWLGSYMSGGVGFTQYATAA.YTDDILDDFLYYGMEYVDDKY.......-GLC.....GTKA.TTEVVHDIASEVTMYGLEQYE-YPALMEDHFGGSQRTAVVSAAAGCSVAFATGNSNAGI.NG.WYLSQILHKEAHSRL.
A0A124G584_9EURY/326-459             ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDEFTYYGMDYIKDKYkvdwqnpSPND.....KVKP.TQEIVNDIATEVNLNGMEQYEQYPTMMEDHFGGSQRAGVLAAACGLSTAIATGNSNAGL.NG.WYLSMLMHKEGWSRL.
A6UWH2_META3/318-443                 ...DQIWLGAYMSGGVGFTQYATAA.YTDDILDDFCYYGLDYVEKKF.......-GRC.....GTKA.TMDVVEDIATEVTLYSLEQYDEYPTLLEDHFGGSQRAAVAAAAAGVSVCMATGNSNAGV.NG.WYLSQIMHKEYHSRL.
J0RY59_9EURY/326-459                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDEFTYYGMDYIKDKYkvdwkhpNAAD.....KVKP.TQDVVNDIATEVTLNAMEQYEQFPTMMEDHFGGSQRAGVIAAASGLSTAIATGNSNAGL.NG.WYLSMLMHKEGWSRL.
D5EAD6_METMS/332-464                 ...DQIWLGSYMSGGVGFTQYSTAA.YTNNILDDNLYYDVEYINDKYdga.aekGIDN.....KVAP.SMDVIKDIATESTLYGLENYEKYPVALEDHFGGSQRATVLSAAAGSAGSLATGNANAGL.SA.WYLCMYLHKEGHGRL.
D3E050_METRM/315-441                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNVLDDFSYFGKDYVEDKY.......GDLC.....SAPN.DMDTVLDVGSAVTFYSLEQYEEYPALLETHFGGSQRAAVVSAASGISTAFATGNAQTGL.SA.WYLAQYLHKEQHSRL.
MCRA_METKA/319-444                   ...DQIWLGSYMSGGVGFTQYATAV.YTDNILDDYVYYGLEYVEDKY.......-GIA.....EAEP.SMDVVKDVATEVTLYGLEQYERYPAAMETHFGGSQRAAVCAAAAGCSTAFATGHAQAGL.NG.WYLSQILHKEGHGRL.
#=GR MCRA_METKA/319-444        SS    ...HIIIIIIISS-SS--HHHHHTT.SBTTHHHHHHHHHHHHHHHHS.......--TT.....TS--.-HHHHHHHHHHHHHHHHHHHHH-HHHHHHS-SHHHHHHHHHHHHHHHHHHHH--HHHHH.HH.HHHHHHHHHHHHT--.
A0A0P8CBK4_9EURY/327-453             ...DQIWLGGYMSGGVGFTMYATPA.YTNDIVDDFLYWADEYASKKY.......GGRG.....KAKA.TIDTVKDIATESTLYSLEAYEKYPTTLEDHFGGSQRATVCSIAAGGATALATGHSQAGL.SA.WYLSMYLHKEAHGRL.
M9SBG6_9EURY/319-446                 ...DQVYLGGYMSGGVGFTQYATAA.YTDNILEDYVYHAVDVINDRY.......GGFC.....GVAPdDYDKQLKLGDEISSYALEMYERYPAVMETHFGGSQRATVTAASTGIAGAMATGVADNGL.NL.WYQSMLQHKERTGRL.
G7WN24_METH6/324-450                 ...DQIWLGSYMSGGVGFTQYATAA.YTNDVLDDFSYYACDYGVDKF.......GDWG.....KAPA.TLETSKDIATETTLYAMEQYESFPTLLEDHFGGSQRSAVMAAASAIGSACLTGNSQSGL.AA.WYLSHLIHKDGWGRM.
MCRX_METFV/319-444                   ...DQVWLGSYMSGGVGFTQYASAT.YTDDILDDFVYYGAEYVEDKY.......-GFC.....GVKP.SMEVVKDIATEVTLYGLEQYEEYPTLLEDHFGGSQRAAVVAAAAGCSTAFATGNSNAGI.NA.WYLSQILHKEGHSRL.
A0A139CTB8_9EURY/331-463             ...DQIWLGSYMSGGVGFTQYATAA.YCNNILDDNLYYNVDYINDKYdga.ankGTDN.....KIAA.NLDVVKDIATESTIYGLENYEKYPTTLEDHFGGSQRATSLSAAAGSAVSIATGNGNAGL.SG.WYLSMYLHKEALGRL.
I7KDB2_METBM/326-459                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDEFTYYGMDYIKDKYkvdwknpSAND.....KVKP.TYDIVNDMATEVTLNAMEQYEQFPTMMEDHFGGSQRAGVIAAASGLTTAIATGNSNAGL.NG.WYLSMLLHKDGWSRL.
L0HD22_METFS/328-461                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDDFTYYGMDYVKDKYgynfrqpGADK.....VIRP.TQDIVNDIATEVTLYSMEQYEKFPTLMEDHFGGSQRAAVMAAAAGLSTSITTGNSNAGL.NA.WYLSMIIHKDGWSRL.
M4YK22_9EURY/317-444                 ...DQIYLGGYMSGGVGFTQYATAA.YTDNILEDYVYHAVDIIKDKY.......GGFC.....GVKAdDYKKQLQLGDEISSYALEMYERYPAVMETHFGGSQRATVTAASTGIAGAMATGVADNGL.NL.WYQSMLQHKERTGRL.
A2STR9_METLZ/326-459                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDDFTYYGMDYIHDKYkvdiknpNPKD.....KVKA.TQEVVNDIATEVNLYGMEQYEQFPTMMEDHFGGSQRAAVLAAASGITTSIGTGNSNAGL.NG.WYLSMLMHKDGWSRL.
A0A124G4P2_9EURY/1-123               ...-----------GVGFTQYATAA.YTDNILDEFTYYGMDYIKDKYkvdwrnpSPND.....KVKP.TYDVVNDMATEVTLNAMEQYEQFPTMMEDHFGGSQRAGVIAAASGLTTSIATGNSNAGL.NG.WYLSMLLHKDGWSRL.
A0A166CWD2_9EURY/316-442             ...DQIWLGSYMSGGVGFTQYASAA.YTDNVLDDFTYYGKEYVEDKY.......GGLC.....EAPN.NMDTVLDVGSEVTFYGLEQYEEYPALLETQFGGSQRASVVSAAAGCSTAFATGNAQTGL.SA.WYLSMYLHKEQHSRL.
A0A101DQI1_9EURY/217-342             ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDDFTYYGREYVEDKY.......-GLA.....EAPN.TMDTVLDIASEVTFYSLEQYEDYPSLLETQFGGSQRAAVAAAAAGCSTGFATGNSQTAL.SG.WYLSMYLHKEQHARL.
A0A0P9HYI1_9ARCH/370-498             ..n-MIWLGFYMSGGIGFSNTVSAAgLAGGVIEDITEELIETTHRYI.......RGIK.....KVPP.KWDIVRFIVDMIIQYVMESYEKFPALSEFHWGGAHKVSIIGSMGAGVASLLTGSSTMGMwAG.HYAIALVMKEGWLR-t
I7LMP5_METBM/326-459                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDEFTYYGMDYIKDKYkvdwknpSAKD.....KIKP.TQDVVNDMATEVTLNAMEQYEQFPTMMEDHFGGSQRAGVIAAASGLTTAIATGNSNAGL.NG.WYLSMLLHKDGWSRL.
A0A166CHN2_9EURY/316-442             ...DQIWLGSYMSGGVGFTQYASAA.YTDNVLDDFCYYGKEYVEDKY.......GGLT.....KAPN.NMDTVLDVGTEVTFYGLEQYEEYPALLETQFGGSQRASVVSAAAGISTAFATGNSQTGL.SA.WYLSMYLHKEQHSRL.
A0A150J3N1_9EURY/320-446             ...DQIYLGSYMSGGVGFTQYATAA.YTDNILEDFVYWGMEHVKDKY.......GDLA.....KQKP.SVKLINDIGTDVAMYCLEQYELYPAVMETHFGGSQRATCISAAAGTSVSMATGNAQAGL.SA.WYLACNIHKEQMGR-f
A0A0Q4BCJ2_9EURY/309-436             ...DQIYLGGYMSGGVGFTQYASAA.YTDNILEDYVYYAIDTIKDKY.......GGFC.....KLDPnNYDKLMELGDNVNTYALEMYERYPAAMEAHFGGSQRATVAAAATGIAGSMATGNADCGV.NM.WYLSMLQHKERTGRL.
A0A0E3NU58_9EURY/330-461             ...DQIWLGSYMSGGVGFTQYATAA.YTDDILDNNTYYDVDYINDKY.......GGAAavdkpTVKA.SLEVVKDIATESTLYGIETYENYPTALEDHFGGSQRATMLAAASGVACSLATGNGNAGL.SG.WYLSMYVHKEAWGRL.
E1RDX4_METP4/326-459                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDEFTYYGMDYLKDKYsvdytnpDPAK.....LIKP.TQEVVNDLATEVNLNAMEQYEQYPTMMEDHFGGSQRAGVMAAACGLTCSIGTGNSNAGL.NG.WYLSMLMHKEGWSRL.
A0A166B5P3_9EURY/318-442             ...DQVWLGSYMSGGVGFTQYASAT.YTDDILDDFVYYGMDYVEKNY.......-GLC.....GAEK.SMDVVRDISTEVTLYGLEQYE-LPTLLETHFGGSQRASVVSAAAGCSTAFATGNSNAGV.NG.WYLSMILHKEAHSRL.
K4MC35_9EURY/331-463                 ...DQIWLGSYMSGGVGFTQYATAA.YTNNILDDNLYYDVDYINDKYdga.aktGKDN.....KVKA.TLEVVKDIATESTIYGLENYEKYPTTLEDHFGGSQRATSLSAAAGCATAIATGNGNAGL.SA.WYLSMYLHKEAHGRL.
A0A166C196_9EURY/316-442             ...DQIWLGSYMSGGVGFTQYATAA.YTDNVLDDFTYFGKDYVEDKY.......GGLT.....QAPN.NMDTVLDVGTEVAFYALEQYEEYPALLETHFGGSQRSSVISAAAGASTAFATGNAQTGL.SA.WYLSMYLHKEQHSRL.
A0B6N6_METTP/324-450                 ...DQIWLGSYMSGGVGFTQYATAA.YTNDVLDDFSYYGVDYAVEKY.......GGFA.....KAPA.NLEVVKDLATEVTLYALEQYESFPTLLEDHFGGSQRAGVTAAASGITCAIATGNSQAGL.AG.WYLSQLLHKEAHGRL.
MCRX_METJA/318-443                   ...DQVWLGSYMSGGVGFTQYASAT.YTDDILDDFVYYGMDYVEKKY.......-GLC.....GVKP.SMEVVKDIATEVTLYGLEQYDEYPALLEDHFGGSQRAGVTAAAAGCSVAFATGNSNAGI.NG.WYLSQILHKEYHSRL.
MCRA_METTH/316-441                   ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDDFTYFGKEYVEDKY.......-GLC.....EAPN.TMDTVLDVASEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATANAQTGL.SG.WYLSMYLHKEQHSRL.
A3CT46_METMJ/326-459                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDEFTYYGMDYIKDKYkvdwknpSADD.....KVKP.TYDTVNDIATEVALNGMEQYEQYPTMMEDHFGGSQRAGVLAAACGLSSSIATGNSNAGL.NA.WYLCMLLHKDGWSRL.
F0T8R3_METLA/316-441                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDDFVYYGKEYVEDKF.......-GMT.....EAPN.NMDTVLDVGSEVTFYALEQFEEYPALLETIFGGSQRASIVAAAAGASTGFATGNAQTGL.SA.WYLSMYLHKEQHSRL.
Q6LWZ5_METMP/319-444                 ...DQIWLGAYMSGGVGFTQYATAS.YTDDILDDFSYYALDYVEKKY.......GR-M.....GTKA.TMDVVEDVAGEVTLYALEQYDDYPALLEDHFGGSQRAAVAAAASGIGVCMATGNSNAGV.NG.WYLSQILHKEYHSRL.
A0A0Q1C669_9EURY/326-420             ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDEYTYYGMDYIKDKYkvdwqnpNEKD.....RVKA.SQDVVNDIATEVCLNAMEQYEQFPTLMEDHFGGSQRA----------------------.--.---------------.
R9TAZ9_9EURY/316-442                 ...DQIYLGSYMSGGVGFTQYATAA.YTDNILEDYVYWAVDLIKSQY.......GGLC.....KSKP.SMDLLEKLGTEVNTYALEMYEKYPAAMESHFGGSQRATVAAASTGIACAMATGNADFGV.NG.WYLSMLQHKERHGRL.
Q8THH1_METAC/329-461                 ...DQIWLGSYMSGGVGFTQYATAA.YTDDILDNNTYYDVDYINDKYnga.anlGTDN.....KVKA.TLDVVKDIATESTLYGIETYEKFPTALEDHFGGSQRATVLAAASGVACALATGNANAGL.SG.WYLSMYVHKEAWGRL.
F6D2D3_METPW/316-442                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNVLDDFCYYGKEYVEDKF.......GGLC.....EAPN.TMETVLDVGSEVTFYALEQYEEYPALLETQFGGSQRAAVTAAAAGCSTGFATGNAQTGL.SA.WYLSMYLHKEQHSRL.
A0A150J824_9EURY/320-446             ...DQIYLGSYMSGGVGFTQYATAA.YTDNILEDFVYWGMEHVKDKY.......GDLA.....KQKP.SVKLINDIGTDVAMYCLEQYELYPAVMETHFGGSQRATCISAAAGTSVAMATGNAQAGL.SA.WYLACNIHKEQMGR-f
J0SAE9_9EURY/326-459                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDEFTYYGMDYIKDKYkvdwrnpSAAD.....RVKP.TQDIVNDIATEVTVNAMEQYEQYPTMMEDHFGGSQRAGVMAAASGLSTAIATGNSNAGL.NG.WYLSMIIHKDAWSRL.
A3CSG1_METMJ/326-459                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDEFTYYGMDYAKDKYkvdwknpSPSD.....KVKP.TQEIVNDLATEVTLNAMEQYEQFPTMMEDHFGGSQRAGVIAAASGLTTSITTGNSNAGL.NG.WYLSMLLHKDGWSRL.
U6EEP1_9EURY/316-441                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDDFTYFGKEYVEDKY.......-GIT.....EAPN.TMDTVLDVGSEVTFYALEQFEDYPALLETIFGGSQRASIVAAAAGCSTAFATGNAQTGL.SA.WYLSMYLHKEQHSRL.
E3GZ51_METFV/319-445                 ...DQIWLGSYMSGGVGFTQYATAS.YTDNILDDFTYYGKEYVEDKY.......GGLA.....EAPH.DFDTILDVATEVTLYSLEQYEEYPTLMEDHFGGSQRAAIAAAASGCSTAFAAGNAQAGL.SG.WYLSQILHKECHARL.
F7XL13_METZD/331-463                 ...DQIWLGSYMSGGVGFTQYATAA.YTNNILDDNLYYDVDYINDKYdga.antGTDN.....KVKP.TLDVVKDIATESTIYGLENYEKYPTALEDHFGGSQRATVLSAAAGSATAIATGHGNAGL.SA.WYLSMYLHKEAHGRL.
A0A101DXX5_9EURY/331-457             ...DQIWLGSYMSGGVGFTQYATAA.YTNNILDDFSYYGYEYAVDKY.......GGPA.....QAPA.TLETVKDIATETAIYAIEQYEYFPTLLEDQFGGSQRAAVVAAAAGIATGLATGNSQAGL.SG.WYLAQYLLKEAEGRL.
Q2FSN0_METHJ/325-458                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDEFTYYGMDYIKDKYkvdwknpSPKD.....KVKP.TQEIVNDIAGEVTLNAMEQYEQFPTMMEDHFGGSQRAGVIAAASGLSVGVATANSNAGL.NG.WYLSMLMHKEGWSRL.
MCRA_METJA/318-444                   ...DQIWLGGYMSGGVGFTQYATAT.YTDDILDDFSYYGYDYITKKY.......GGCN.....SVKP.TMDVVEDIATEVTLYGLEQYDTFPALLEDHFGGSQRAGVTAAAAGITTALATGNSNAGV.NG.WYLSQILHKEYHSRL.
A5ULZ2_METS3/316-442                 ...DQIWLGSYMSGGVGFTQYATAA.YTDDVLDDFTYYGKDYVEDKY.......GGLT.....EAPN.NMDTVLDVGSEVSFYALEQYEEYPALLETHFGGSQRASVISAAAGCSTAFATGNAQTGL.SA.WYLGMYLHKEQHSRL.
Q8PXH8_METMA/329-461                 ...DQIWLGSYMSGGVGFTQYATAA.YTDDILDNNTYYDVDYINDKYnga.anlGTDN.....KVKA.TLDVVKDIATESTLYGIETYEKFPTALEDHFGGSQRATVLAAASGVACALATGNANAGL.SG.WYLSMYVHKEAWGRL.
B8GE93_METPE/325-451                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDEFVYYGMDYLKSKY.......GGYS.....QAPA.TQEVVNDLATEVTLNAMEQYEQFPTMMEDHFGGSQRASVIAAASGLTTSIGTGNSNAGL.NG.WYLSMLMHKEGWSRL.
D7E8X7_METEZ/332-464                 ...DQIWLGSYMSGGVGFTQYATAA.YTNNILDDNLYYDIEYINDKYnna.gkpGADN.....KAPA.TMDVVKDIATESTLYGLENYEKYPTALEDHFGGSQRATVLSAAAGSATSIATGNSNAGL.SA.WYLSMYLHKEAHGRL.
A0A059TIR1_9EURY/318-445             ...DQVYLGGYMSGGVGFTQYATAA.YTDNILEDYVYHGIDTIKDRY.......GGFC.....GVKPdDYKKQLKLADEISSYALEMYERYPAVMEIHFGGSQRATVTAASTGIITAMATGVADNGL.NA.WYQSMLQHKERTGRL.
A0A166A6T9_9EURY/316-442             ...DQIWLGSYMSGGVGFTQYASAA.YTDNVLDDFAYYGKEYVEDKY.......GGLT.....QAPN.NMDTVLDVGSEVTFYGLEQYEEYPALLETQFGGSQRASVVSAAAGISTAFATGNSQTGL.SA.WYLSMYLHKEQHSRL.
MCRA_METBF/329-461                   ...DQIWLGSYMSGGVGFTQYATAA.YTDDILDNNTYYDVDYINDKYnga.atvGKDN.....KVKA.SLEVVKDIATESTLYGIETYEKFPTALEDHFGGSQRATVLAAAAGVACSLATGNANAGL.SG.WYLSMYLHKEAWGRL.
#=GR MCRA_METBF/329-461        SS    ...HHIIIIIITS-TT--HHHHHCC.CBTTHHHHHHHHHHHHHHHHTTTT.TSS-SSS.....----.-HHHHHHHHHHHHHHHHHHHHH-HHHHHHT-SHHHHHHHHHHHHHHHHHHHHS-HHHHH.HH.HHHHHHHHHHHHT--.
D1YVW6_METPS/323-448                 ...DQIWLGSYMSGGVGFTQYATAA.YTDDILDDFTYYGYDYAKGKY.......-KIG.....QTKP.TMDIVNDLSTEVTLYGIEQYEKYPTTLEDHFGGSQRATVLSAAAGVTTAIATGNSNAGL.SG.WYMSMYLHKEAWGRL.
A0A101IW49_9EURY/1-60                ...----------------------.---------------------.......----.....----.----------------MEQYEQFPTMMEDHFGGSQRAGVIAAASGLTTSITTGNSNAGL.NG.WYLSMLLHKDGWSRL.
A0A0A7LF46_9EURY/319-446             ...DQVYLGGYMSGGVGFTQYASAT.YTDNILEDYVYHAVDVIKDKY.......GGLC.....KLDPsKYDELMKLGDDVNAYALEMYEKYPAIMETHFGGSQRATVAAATTGIAGSMATGIADCGL.NM.WYLSMLQHKERTGRL.
MCRX_METTH/318-443                   ...DQVWLGSYMSGGVGFTQYATAA.YTDDILDDFVYYGMEYVDDKY.......-GIC.....GTKP.TMDVVRDISTEVTLYSLEQYEEYPTLLEDHFGGSQRAAVAAAAAGCSTAFATGNSNAGI.NG.WYLSQILHKEAHSRL.
D7DUH5_METV3/319-444                 ...DQIWLGSYMSGGVGFTQYATAS.YTDDILDDFSYYGLDYVEKKY.......-GRC.....GTKA.TMDVVEDIASEVTLYALEQYDEYPALLEDHFGGSQRAAVAAAAAGISTCMATGNSNAGV.NG.WYLSQILHKEYHSRL.
Q12TF8_METBU/331-463                 ...DQIWLGSYMSGGVGFTQYATAA.YTNNILDDNLYYNVDYINDKYdga.ankGADN.....KVKA.TMDVVKDIATESTIYGIENYEKYPTALEDHFGGSQRATVLSAAAGSATALATGNGNAGL.SG.WYLSMYLHKEALGRL.
A0A120K0D9_9EURY/316-442             ...DQIWLGSYMSGGVGFTQYATAA.YTDNVLDDFTYYGKDYVEDKY.......GDLC.....SAPN.NMDTVLDVGSEVAFYALEQYESYPALLETHFGGSQRASVISAAAGCSTAFATGNAQTGL.SA.WYLSMYLHKEQHSRL.
Q2NHZ8_METST/318-443                 ...DQVWLGSYMSGGVGFTQYATAA.YTDEILDDFIYYGKDYVEGKY.......GGLC.....QAEA.TSEVVKDIASEVTLYGLEQYE-IPAALEDHFGGSQRAAVLAAGAGCSVAFATANSNAGV.NG.WYLSQLLHKEGHSRL.
R9SLW2_9EURY/316-442                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDDFAYYGKDYVEDKY.......GGLT.....EAPN.NMDTVLDVGSEVTFYALEQYDEYPALLETQFGGSQRAAVTAAASGCCTAFATGNSQTGL.SA.WYLSQYLHKEQHSRL.
A0A126R1N8_9EURY/315-441             ...DQIWLGSYMSGGVGFTQYATAA.YTDNVLDDFSYFGKDYVEDKY.......GGLC.....EAPN.NMDTVLDVGSEVAFYSLEQYEEYPALLETHFGGSQRAAVISAASGISTAFATGNAQTGL.SA.WYLAQYLHKEQHSRL.
H1YXH9_9EURY/326-459                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDEFTYYGMDYIKDKYgvdytnpDPAK.....LVKP.TQEVVNDIASEVNLNAMEQYEQFPTMMEDHFGGSQRAGVMAAACGLSTSIATGNSNAGL.NG.WYLSMLMHKEGWSRL.
L0HIJ7_METFS/327-453                 ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDDFTSYGVDYVKKKH.......GALG.....KVKA.TQDVVNDIASEVTLYGMEQYEEFPTTLESHFGGSQRATVLAAASGVSTALATANSNAGL.NG.WYMSMLMHKEAWSRL.
D5VQU8_METIM/318-444                 ...DQIWLGSYMSGGVGFTQYATAS.YTDDILDDFSYYGYDYINKKY.......GGCN.....SVKP.TMDVVEDIATEVTLYALEQYDTYPALLEDHFGGSQRAAVTAAASGISVALATGNSNAGL.NG.WYLSQILHKEYHSRL.
#=GC SS_cons                         ...HHIIIIIITS-TT--HHHHHCC.CBTTHHHHHHHHHHHHHHHHTTTT.TSS-STT.....TS--.-HHHHHHHHHHHHHHHHHHHHH-HHHHHHT-SHHHHHHHHHHHHHHHHHHHHS-HHHHH.HH.HHHHHHHHHHHHT--.
#=GC seq_cons                        ...DQIWLGSYMSGGVGFTQYATAA.YTDNILDDFsYYGhDYlcDKY.......uuhs.....cscs.ohDlVpDlATEVTlYulEQYEpYPshhEDHFGGSQRAuVlAAAuGhoTAhATGNusAGL.su.WYLSMhLHKEsauRL.
//
DBGET integrated database retrieval system