GenomeNet

Database: Pfam
Entry: MSP1_C
LinkDB: MSP1_C
Original site: MSP1_C 
#=GF ID   MSP1_C
#=GF AC   PF07462.10
#=GF DE   Merozoite surface protein 1 (MSP1) C-terminus
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_21542 (release 10.0)
#=GF GA   29.80 29.80;
#=GF TC   163.90 163.40;
#=GF NC   24.40 23.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12466500
#=GF RT   Mosaic organization and heterogeneity in frequency of allelic
#=GF RT   recombination of the Plasmodium vivax merozoite surface
#=GF RT   protein-1 locus. 
#=GF RA   Putaporntip C, Jongwutiwes S, Sakihama N, Ferreira MU, Kho WG,
#=GF RA   Kaneko A, Kanbara H, Hattori T, Tanabe K; 
#=GF RL   Proc Natl Acad Sci U S A 2002;99:16348-16353.
#=GF DR   INTERPRO; IPR010901;
#=GF CC   This family represents the C-terminal region of merozoite
#=GF CC   surface protein 1 (MSP1) which are found in a number of
#=GF CC   Plasmodium species. MSP-1 is a 200-kDa protein expressed on the
#=GF CC   surface of the P. vivax merozoite. MSP-1 of Plasmodium species
#=GF CC   is synthesised as a high-molecular-weight precursor and then
#=GF CC   processed into several fragments. At the time of red cell
#=GF CC   invasion by the merozoite, only the 19-kDa C-terminal fragment
#=GF CC   (MSP-119), which contains two epidermal growth factor-like
#=GF CC   domains, remains on the surface. Antibodies against MSP-119
#=GF CC   inhibit merozoite entry into red cells, and immunisation with
#=GF CC   MSP-119 protects monkeys from challenging infections. Hence,
#=GF CC   MSP-119 is considered a promising vaccine candidate [1].
#=GF SQ   25
#=GS W7AFH8_PLAVN/1031-1338      AC W7AFH8.1
#=GS A0A0L7LXP3_PLAF4/959-1513   AC A0A0L7LXP3.1
#=GS A0A024VR46_PLAFA/953-1507   AC A0A024VR46.1
#=GS W7AFH8_PLAVN/1321-1549      AC W7AFH8.1
#=GS A0A024W7K7_PLAFA/401-664    AC A0A024W7K7.1
#=GS W7KFP9_PLAFO/981-1536       AC W7KFP9.1
#=GS Q4XPN3_PLACH/1-132          AC Q4XPN3.1
#=GS A0A024W7X9_PLAFA/822-1107   AC A0A024W7X9.1
#=GS A0A0D9QFB7_PLAFR/1044-1360  AC A0A0D9QFB7.1
#=GS K6UUJ2_9APIC/1011-1622      AC K6UUJ2.1
#=GS Q4X6U4_PLACH/1-208          AC Q4X6U4.1
#=GS Q4XT02_PLACH/1-314          AC Q4XT02.1
#=GS W7A8Y0_9APIC/997-1362       AC W7A8Y0.1
#=GS A0A0L0CYS7_PLAFA/937-1491   AC A0A0L0CYS7.1
#=GS Q8I0U8_PLAF7/981-1536       AC Q8I0U8.1
#=GS A0A0L1I842_PLAFA/946-1501   AC A0A0L1I842.1
#=GS A0A0D9QFB7_PLAFR/1351-1657  AC A0A0D9QFB7.1
#=GS W7JYM8_PLAFA/979-1534       AC W7JYM8.1
#=GS Q4Z273_PLABA/843-1376       AC Q4Z273.1
#=GS W4IYZ7_PLAFP/916-1471       AC W4IYZ7.1
#=GS B3L2X8_PLAKH/1056-1647      AC B3L2X8.1
#=GS W7A8Y0_9APIC/1378-1612      AC W7A8Y0.1
#=GS A5K724_PLAVS/1001-1576      AC A5K724.1
#=GS MSP1_PLAYO/1058-1591        AC P13828.1
#=GS A0A024WQJ1_PLAFA/971-1525   AC A0A024WQJ1.1
W7AFH8_PLAVN/1031-1338                 ..............qgts---VQAESEDEMFVDDFELDNFYKSYLQQVDGN.NTQFINFIKSKKELIKALTPEKVNQLYLDIAHLKELSEHYYNRYYKYKLKLERLYQKHEQITAANQKVREVSILKSRLLRRKKYINGTFYVLPGYANFFNKRREAEKQYVDNAIKNTDMLLKYYKARSKYFTSEAVPLKTLTKTSIDREANYLKIEKFRAYSRLELRLKKNINLGKERITYVSGGLHHVFEEFKELLENKGYIGKSNPENAPEVFKAFEQYKELLPK..gVTIPAPVV.....TPV......VTPPVA-PAADTTS....-NPPAAVVPLTEG------.-----.---.................................--.------------------------------...--...-----------.------------------------------------------------------------------------------------------------------------------------------------------------...........---------.....................-------------------------------------------eestkvvass..............................
A0A0L7LXP3_PLAF4/959-1513              ..................NLGNKTKVPNPLTISTTEMEKFYENILKNNDTYfNDDIKQFVKSNSKVITGLTETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNPHNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EAKV.....TTV......VTPP--QPDVTPSP....LSVRVSGSSGSTKEETQIP.TSGSL.---.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN...DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIITFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEFPssppt.tppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH........................................
A0A024VR46_PLAFA/953-1507              ..................NLGNKTKVPNPLTISTTEMEKFYENILKNNDTYfNDDIKQFVKSNSKVITGLTETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNPYNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRALSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EAKV.....TTV......VTPP--QPDVTPSP....LSVRVSGSSGSTKEETQIP.TSGSL.---.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN...DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEFPssppt.tppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKNEAH........................................
W7AFH8_PLAVN/1321-1549                 ..........avvplteg---------------------------------.-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------...--------.....---......--------------....-------------------.-----.---.................................--.------------EESTKVVAS---SDNDDD...DD...MDQIASAQSTE.TQVTDILDAFKNEGEYIYTKSLGNTYKSFKKHMLKEFSIITEDIIAGLNYKLEKRNDFLDVLSYELALFKDINTNKFVVKNPYQLLDNDKKDKQMVNLKYAIKGVSDDIETVTDGIAFFNKMIELYKPQLNAVNEQIAAIGKET...........N--ENDEKK.....................-KYAPIFEDLKGLYETILEGAKEFSELLQHKLENYKIEKAGF-d.......................................
A0A024W7K7_PLAFA/401-664               ypngivyplpltdihnsl---------------------------------.-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------...--------.....---......--------------....-------------------.-----.---.................................--.----AADNDKNSYEDDSLVVLPIFGESEDN...DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEFPssppt.tppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH........................................
W7KFP9_PLAFO/981-1536                  ..................NLGNKTKVPNPLTISTTEMEKFYENILKNNDTYfNDDIKQFVKSNSKVITGLTETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNPHNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EAKV.....TTV......VTPP--QPDVTPSP....LSVRVSGSSGSTKEETQIP.TSGSL.---.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN...DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEKFpssppttppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH........................................
Q4XPN3_PLACH/1-132                     ..................---------------------------------.-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------...--------.....---......--------------....-------------------.-----.---.................................--.------------------------------...--...-----------.-------------------------------------------------------------LSYELALFKDINTNKFVVKNPYQLLDNDKKDKQMINLKYAIKGVTEDIETATDGIEFFNKMVELYKPQLNAVNEQIAAIEKET...........--TDKEEKK.....................-KYVPIFEDLKGLYETILNGAEEFSELLQHKLENYKIEKAGF-d.......................................
A0A024W7X9_PLAFA/822-1107              ..................NLGNKTKVPNPLTISTTEMEKFYENILKNNDTYfNDDIKQFVKSNSKVITGLTETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNPHNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EAKV.....TTV......VTPP--QPDVTPSP....LSVR---------------.-----.---.................................--.------------------------------...--...-----------.------------------------------------------------------------------------------------------------------------------------------------------------...........---------.....................-------------------------------------------nyn.....................................
A0A0D9QFB7_PLAFR/1044-1360             ..............nvsv----RASNEDEPKVTIVQMEKPYDRYLSQMDTY.NDYFAKFLESQKENINNMNKEQWETLGAEIEQLKEKIQVSLDHYGKYKLKLERFMKKKNKISNSKEHIKKLTSLKNKLEKRKKFLNNPSSVLKNYTVFFNKKKEAERKEVENTLKNTELLLKYYKAQAKYYIGEPFPLKTLSEESLQKEDNYLNLEKFRVLSRMEGRLGNNINLEKETITYLSSGLHHVFTELKEIINNKRYTGSDHKKNSEAVKKALQEYQDLLPK...VATKASPSlpaapAQP......VTPPVT-PPVTPAE....ETEESAA---EAEESAPT-.-----.---.................................--.------------------------------...--...-----------.------------------------------------------------------------------------------------------------------------------------------------------------...........---------.....................-------------------------------------------appvkqeagptae...........................
K6UUJ2_9APIC/1011-1622                 .............elavs--GSSEEEPE---VKIEELKNIYEKHLSQIDNY.NDYFKKFLESQKENITKMDDTQWKALGVEIEELKKKIQVSLDHYEKYKLKLDRFMKKKNKISNSKEQIKKLTSLKNKLQRRQNLLNNPTSVLKNYTVFFNKKREAEKKEVENTLKNTEILLKYYKARAKYYIGEPFPLKTLSEESMQKEDNYLNLERFRVLSRMEGRLGNNIDLEKENISYLSSGLHHVFTELKEIINNKRYSGNDHAKNTAAVKVALQAYQELLPK...VTTQEGAS.....VPAggaapvVAAPAPVVAGPPAG....----GAG--GAGAGPVEGPaAPGTVaPAGapgvaaggagaepapgavvpgagapeasvttpgET.GETGVVAAQDYAEDYDKVIALPLFGNNDDD...GDdkeADQVTMGEAES.EAPEIIVPQGINEYDVVYIKPLAGMYKTIKKQLENHVNALNTNIIDMLDSRLKKRNYFLDVLNSDLNPYKYSSSGEYIIKDPYKLLDLEKKKKLLGSYKYIGASVDKDMVTANDGLAYYQKMGDLYKKHLDEVNEQIKEVEANI...........NKQDAEIKKiesdtsktaqknqlnakkeelQKYLPFLSSIQKEYNTLVNKVHSYTDTLKKIINNCQIEKKETE........................................
Q4X6U4_PLACH/1-208                     .................m------------FVDDFEVDNFYKSYLQQVDGN.NTQFIDFIKSKKELINALTPEKVNQLYLDIAHLKELSEHYYNRYYKYKLKLERLYQKHEQIEAANQKVKEISVLKSRLLKRKKYINGTFYVLSGFANFFNKRREAEKQYVDNAIKNTDMLLKYYKARSKYFTSEAVPLKTLTKTSIDREANYLKIEKFRAYSRLELRLKKNINLGKERITYVSGGL-----------------------------------------...--------.....---......--------------....-------------------.-----.---.................................--.------------------------------...--...-----------.------------------------------------------------------------------------------------------------------------------------------------------------...........---------.....................-------------------------------------------........................................
Q4XT02_PLACH/1-314                     ..................---------------------------------.---------------------------------------------KYKLKLERLYQKHEQIEAANQKVKEISVLKSRLLKRKKYINGTFYVLSGFANFFNKRREAEKQYVDNAIKNTDMLLKYYKARSKYFTSEAVPLKTLTKTSIDREANYLKIEKFRAYSRLELRLKKNINLGKERITYVSGGLHHVFEEFKELLKNKGYTGKTNPENAPEVIKAFEQYKELLPK...GATTPAPV.....VTP......AVAPAS-ATTTPAD....E-------PAAAAAAAAAP.ASGSAtTTG.................................--.-----------GENGTPVVANSDNDDDDDD...DD...MDQIANAQSTD.GEVKDILDEFKSENEYIYTKSLGNTYKSFKKHMLKEFSMIKEDIITGLNYKLEKR-----------------------------------------------------------------------------------------...........---------.....................-------------------------------------------........................................
W7A8Y0_9APIC/997-1362                  ...........ntvkanc-----DDKPEDLL---MQMEMIYEKHISEMDKY.NENFNKFLESKKQKITTMKDEEWKALGTEIEQLKKKIQVSLDHYGKYKLKLERFLKKKKKVTNTKGQIKGLTILKNKLERRKNLLNIPTSVLKNFTVFFNKKRESEKKEVENTLKNTDILLNYYKALAKYYMSEPFPLKTISEESLQKEDNYLNLKKFKVLSRMEGRLGDNIQLEKENISYLSSGLHHVFTELKEIIDNKKYSGNRTGTSSTSGNRRTSISGNTSS-...-STSSTRS.....TRS......NNS----RRGSRRG....-SSRSSSWSTSIRRSPSSN.STISN.STGrs............................nnnNT.RGRRRSRSNNNNNNN---------------...--...-----------.------------------------------------------------------------------------------------------------------------------------------------------------...........---------.....................-------------------------------------------trrrrrsrsnnnnnnnnndtrrrrinnndnnnnnnnnntr
A0A0L0CYS7_PLAFA/937-1491              ..................NLGNKTKVPNPLTISTTEMEKFYENILKNNDTYfNDDIKQFVKSNSKVITGLTETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNPHNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRALSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EAKV.....TTV......VTPP--QPDVTPSP....LSVSVSGSSGSTKEETQIP.TSGSL.---.................................LT.ELQQVVQSQNYDEEDDSLVVLPIFGESEDN...DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIITFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEFPssppt.tppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH........................................
Q8I0U8_PLAF7/981-1536                  ..................NLGNKTKVPNPLTISTTEMEKFYENILKNNDTYfNDDIKQFVKSNSKVITGLTETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNPHNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EAKV.....TTV......VTPP--QPDVTPSP....LSVRVSGSSGSTKEETQIP.TSGSL.---.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN...DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEKFpssppttppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH........................................
A0A0L1I842_PLAFA/946-1501              ..................NLGNKTKVPNPLTISTTEMEKFYENILKNNDTYfNDDIKQFVKSNSKVITGLTETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNPHNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EAKV.....TTV......VTPP--QPDVTPSP....LSVRVSGSSGSTKEETQIP.TSGSL.---.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN...DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEKFpssppttppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKNEAH........................................
A0A0D9QFB7_PLAFR/1351-1657             .........vkqeagpta---------------------------------.-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------...----EAPV.....AAE......TAAEAPEPETETETetetETGETQTREESAAGTVQTT.PAAG-.GEG.................................QTgQTTQDVKAQD----YDEVIALPLFGNNDDDgdyDE...EDQVTTGEAEN.AQPEVIIPEGISEYEVVYIKPLAGIYNTIKKQLANHVAAFNTNIIDMLDSRLKKRSYFLSVLESDFNPFKYSSSGEYIMKDPYKLLDYEQKKKLLGSYKYISASIDKDIATAKDGLAYFNKMSELYKNHMDAVHAHIQSIEKGD...........SETDGDQLNakn...............eeaKKYLPFLNSIQKEYETLMNKVHIYTDNLKKFMNKYPIEKKETE........................................
W7JYM8_PLAFA/979-1534                  ..................NLGNKTKVPNPLTISTTEMEKFYENILKNNDTYfNDDIKQFVKSNSKVITGLTETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNPHNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EAKV.....TTV......VTPP--QPDVTPSP....LSVRVSGSSGSTKEETQIP.TSGSL.---.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN...DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEKFpssppttppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH........................................
Q4Z273_PLABA/843-1376                  .................s-ITTRAESEEDIPADDFELDNLYKSYLQRIDGN.NTEFINFIKSKKELIKALTPEKVNQLYLEIAHLKELSEHYYDRYYKYKLKLERLYEKHEQIQVSNRQIRELSILKARLLKRKQNINGIFYILSGYVNFFNKRREADKQYVDNALKNNDMLLKYYKARIKYFTSEAVPLKTLTKASLDRETNYLKIEKFRAYSRLELRFKKNINLGKEKISYVSGGLYHVFEEFKELLKNKNYTGKTNPDTVPEVTNAFEQYKELLPKgvtASASPAAA.....TTP......TSADAATQRATPES....RSGSGSG-SGSVVSSTPEE.VARS-.GSG.................................--.--------------ENAVVSGSSVDDNDDD...D-...IDQIASGQSEN.AQEKNILEAFKNESEYLYARSLGITYKSLKKHMIREFSTIKEDMTTGLNNKLQKRNDFLEVLNHELDLFKDLSTNKYVIRNPYQLLDNDKKDKQIVNLKYAAKGVNEDIETTADGIKFFNKMIELYKIQLAAVKEQIDAIEAAT...........--TDKDEKK.....................-KYVPIFEDLKGLYETILGQSEEYIEVLQNRLDSYKNEKTEFE........................................
W4IYZ7_PLAFP/916-1471                  ..................NLGNKTKVPNPLTISTTEMEKFYENILKNNDTYfNDDIKQFVKSNSKVITGLTETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNPHNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EAKV.....TTV......VTPP--QPDVTPSP....LSVRVSGSSGSTKEETQIP.TSGSL.---.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN...DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEKFpssppttppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH........................................
B3L2X8_PLAKH/1056-1647                 ..............gvtv----QASSEEEPETNIVNVEKIYEKHLSQMDKY.NDYFIKFLESQKEKITSMTEEQANALGAEIEALKKKVQVSLDHYGKYKLKLERFLEKKNKISNSKEHIKKLTSLKNKLERKLNFLNNPTSVLKNYIIFFNKKKEAEKKEVENTLKNTEILLKYYKARAKYYIGEPFPLKTLSEESLQKEDNYLNLEKFRVLSRMEGRLGNNINLEKENISYLSSGLHHVFTELKEIIKNKKYTGNDHAKNTTAVKEALQAYEELLPK...VATQT-AS.....LPP......VAPPAVVPPVVPEA....EAEAEAEAEAEPATSTQPA.TADTA.APTqtpaaptqtpaepata.tattgetaaapaapapVE.VQNAEVKAQEYGEDYDKVITLPLFGNDEDD...VEdqeEKQIITGEAEN.AQPENIVPEGINEYEVVYIKPLAGMYKSIKKQLENHVAAFNTNITDMLDSRLKKRNYFLDVLDSELNPFKYSSSGEYIIKDPYKLLDLEQKKKLLGSYQYIGASVDKDLITAKDGMEYYNKMGELYKQHLEAVNAQIKEIEASVpge....qsqlNAQKEELK-.....................-KYLPFLNSIQKEYESLVNMAHTYKENLKKFINNCQIEKKETE........................................
W7A8Y0_9APIC/1378-1612                 .............degyd---------------------------------.-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------...--------.....---......--------------....-------------------.-----.---.................................--.------------------------EEEEEN...KE...ADQVTTGEDENqETPEVIVPPGINEYEVVYIKPLAGMYKTIKKQLENHVTALNTNITDMLDSRFKKRNYFLGVLNFDLNPFKYSSTGDNIIKDPYKLLDLEKKKKMLGGYNYIGMSIEKDLATANDGLAYYNKMNDLYKKQLDAVNKKIKEVEDEIkkip..dgepnA-------Atnnqli.........avkeesKSYLPFLNSIKKEYESLVSMVITYTNNLKKFINNFQIEKRETE........................................
A5K724_PLAVS/1001-1576                 .................v-GGNSEEKPE---ADTAQVEKFYEKHLSQIDKY.NDYFQKFLESQKDEITKMDETKWKALGAEIEELKKKLQVSLDHYGKYKLKLERLLKKKNKISNSKDQIKKLTSLKNKLERRQNLLNNPTSVLKNYTAFFNKKRETEKKEVENTLKNTEILLKYYKARAKYYIGEPFPLKTLSEESMQKEDNYLNLEKFRVLSRLEGRLGKNIELEKENISYLSSGLHHVLTELKEIIKNKKYSGNDHTKNIAAVKEALQAYQELIPK...VTTQEGAS.....TTA......ATLPVTVPSAVPGG....L--PGAGVPGAAAGLTPPP.PAGSVpATGpga...........................aagST.EENVAAKAQDYAEDYDKVIALPLFGNNDDD...GE...EDQVTTGEAES.EAPEILVPAGISDYDVVYLKPLAGMYKTIKKQLENHVNAFNTNITDMLDSRLKKRNYFLEVLNSDLNPFKYSSSGEYIIKDPYKLLDLEKKKKLIGSYKYIGASIDMDLATANDGVTYYNKMGELYKTHLDGVKTEIKKVEDDI...........KKQDEELKKlgnvnsqdskknefiakkaelEKYLPFLNSLQKEYESLVSKVNTYTDNLKKVINNCQLEKKEAE........................................
MSP1_PLAYO/1058-1591                   ................gi--RSRAESEEDMPADDFELDNLYKSYLQQIDGN.NTEFINFIKSKKELIKALTPEKVNQLYLEIAHLKELSEHYYDRYSTYKLKLERLYNKHEQIQLTNRQIRDLSILKARLLKRKQTLNGVFYILNGYVNFFNKRREAEKQYVDNALKNTDMLLKYYKARTKYFTSEAVPLKTLSKASLDRESNYLKIEKFRAYSRLELRLKKNINLGKERISYVSGGLHHVFEEFKELIKDKDYTGKKNPDNAPEVTNAFEQYKELLPKgvtVSTPAVAV.....TTT......LAADAP---ATPEG....-AVPGAV-PGAVPGAVPGA.VPGAVpGSG.................................--.--------------TDTRVAGSSVDDNEDD...D-...IYQIASGQSED.APEKDILSEFTNESLYVYTKRLGSTYKSLKKHMLREFSTIKEDMTNGLNNKSQKRNDFLEVLSHELDLFKDLSTNKYVIRNPYQLLDNDKKDKQIVNLKYATKGINEDIETTTDGIKFFNKMVELYNTQLAAVKEQIATIEAET...........NDTNKEEKK.....................-KYIPILEDLKGLYETVIGQAEEYSEELQNRLDNYKNEKAEFE........................................
A0A024WQJ1_PLAFA/971-1525              ..................NLGNKTKVPNPLTISTTEMEKFYENILKNNDTYfNDDIKQFVKSNSKVITGLTETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNPHNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EAKV.....TTV......VTPP--QPDVTPSP....LSVRVSGSSGSTKEETQIP.TSGSL.---.................................LT.ELQQVVQSQNYDEEDDSLVVLPIFGESEDN...DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEFPssppt.tppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH........................................
#=GC seq_cons                          .....................spscs.p...hsshEh-phY-phLpp.DsY.N-phhpFlcSppchIsuhTcpphNsLssEIccLK-plQlShDhYsKYKLKL-RLapKKcclspsK.QIKcLTlLKppLpp+hp.LNsPasVLpNassFFNKK+EAEhtEsENTLcNTclLLKaYKuhsKYYsuEusPLKTLSEsSlQpEDNYhNLEKFRsLS+l-G+LscNlpLGKc+lSaLSSGLHHlhTELKElIKNKpYTGsssscNstpVpcAhppYcphLP........puts.....Tss......lssP...PssoPss.....sstsus.suusttts..s.ssso..............................................st.pp.spptDpllshs.hu-s-Ds...D-...hDQlsoGEu.s.sp.-sIlsth.NEY-VlYlKPLAGhY+SlKKQltppl.shNhNlsDhLsSRLKKRpYFL-VLpp-L..FKa.Sos-YIIcDsaKLLs.EpKpphltuYKYIttSV-pDIthAp-GlsYapKhhthYKspL-ulpc.Icp.cc.............stpDcppKc......................KaLPFLsslcp.YpsLlsphcpYh.sLKthlNshplEKpEsc........................................
//
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