GenomeNet

Database: Pfam
Entry: MSP7_C
LinkDB: MSP7_C
Original site: MSP7_C 
#=GF ID   MSP7_C
#=GF AC   PF12948.4
#=GF DE   MSP7-like protein C-terminal domain
#=GF AU   Bateman A
#=GF SE   Jackhmmer:Q95VZ1
#=GF GA   27.00 27.00;
#=GF TC   30.70 30.70;
#=GF NC   23.70 23.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   11551634
#=GF RT   The 22 kDa component of the protein complex on the surface of
#=GF RT   Plasmodium falciparum merozoites is derived from a larger
#=GF RT   precursor, merozoite surface protein 7.
#=GF RA   Pachebat JA, Ling IT, Grainger M, Trucco C, Howell S,
#=GF RA   Fernandez-Reyes D, Gunaratne R, Holder AA;
#=GF RL   Mol Biochem Parasitol. 2001;117:83-89.
#=GF DR   INTERPRO; IPR024781;
#=GF CC   MSP7 is a protein family the malaria parasite that has been
#=GF CC   found to be associated with processed fragments from the MSP1
#=GF CC   protein in a complex involved in red blood cell invasion.
#=GF SQ   40
#=GS A5K7Z9_PLAVS/181-306  AC A5K7Z9.1
#=GS Q8IDY3_PLAF7/473-615  AC Q8IDY3.1
#=GS C0H5F3_PLAF7/202-298  AC C0H5F3.1
#=GS W7JPM3_PLAFO/202-298  AC W7JPM3.1
#=GS A5K7Z6_PLAVS/255-376  AC A5K7Z6.1
#=GS B3L8N7_PLAKH/265-386  AC B3L8N7.1
#=GS Q8IDY0_PLAF7/152-276  AC Q8IDY0.1
#=GS A5K7Z7_PLAVS/259-380  AC A5K7Z7.1
#=GS W7JQ58_PLAFO/152-276  AC W7JQ58.1
#=GS Q4Y1Q1_PLACH/1-120    AC Q4Y1Q1.1
#=GS W7JPL9_PLAFO/71-194   AC W7JPL9.1
#=GS Q8IDX9_PLAF7/252-375  AC Q8IDX9.1
#=GS Q8IDX8_PLAF7/215-346  AC Q8IDX8.1
#=GS Q8IDY4_PLAF7/171-294  AC Q8IDY4.1
#=GS A5K7Z1_PLAVS/257-379  AC A5K7Z1.1
#=GS W7K1Q0_PLAFO/171-294  AC W7K1Q0.1
#=GS B3L8P0_PLAKH/253-376  AC B3L8P0.1
#=GS Q8IDY5_PLAF7/331-454  AC Q8IDY5.1
#=GS W7K0P1_PLAFO/60-196   AC W7K0P1.1
#=GS Q4YB69_PLABA/1-123    AC Q4YB69.1
#=GS A5K7Z8_PLAVS/1-73     AC A5K7Z8.1
#=GS Q8IDY1_PLAF7/60-196   AC Q8IDY1.1
#=GS A5K7Z0_PLAVS/322-445  AC A5K7Z0.1
#=GS W7JQ54_PLAFO/433-575  AC W7JQ54.1
#=GS W7K1Q5_PLAFO/1-52     AC W7K1Q5.1
#=GS A5K7Z3_PLAVS/244-367  AC A5K7Z3.1
#=GS A5K7Z4_PLAVS/283-403  AC A5K7Z4.1
#=GS Q4XIX6_PLACH/1-82     AC Q4XIX6.1
#=GS A5K7Y9_PLAVS/247-369  AC A5K7Y9.1
#=GS Q7RMN1_PLAYO/188-310  AC Q7RMN1.1
#=GS Q4YB67_PLABA/208-327  AC Q4YB67.1
#=GS Q4XQ10_PLACH/1-81     AC Q4XQ10.1
#=GS A5K7Z5_PLAVS/322-445  AC A5K7Z5.1
#=GS B3L8N6_PLAKH/145-270  AC B3L8N6.1
#=GS W7KB65_PLAFO/252-375  AC W7KB65.1
#=GS Q7RMM9_PLAYO/1-96     AC Q7RMM9.1
#=GS B3L8N8_PLAKH/297-411  AC B3L8N8.1
#=GS A5K800_PLAVS/276-412  AC A5K800.1
#=GS Q7RMN0_PLAYO/196-315  AC Q7RMN0.1
#=GS W7JPM7_PLAFO/215-346  AC W7JPM7.1
A5K7Z9_PLAVS/181-306             ...............................LKYSDELYE..................DILTSL.NKKGCEEGTEN............NNKYNEFKKEYEMFiSLNKEEYEIIEKLVDAFSMY..NDSIDEDAD......SVYEAIKKSFTDPKFRKEFKD.FMNGIYAYAK.RKHYIRGTQ.TEKAKTYLTLFENVIN.....
Q8IDY3_PLAF7/473-615             ...............................QKHNQDLYNikknndlpqyeesnktykKIFSNEhEPRPMITTSRY............ENKISN-DNNNNNY.NLNEQERKLIKNMIDIFIYTykLNYTNSK--......SISKLFKNNLLKKNFRTYFTN.YIYTLFNYGK.TYNFLTPYN.KDNDHMYRQLFDEAVQ.....
C0H5F3_PLAF7/202-298             ..............................l-KNIDKLCD..................ELLIYL.YKKNEVNTNNY............LRKYDEFKNKFDQF.LLNVNKYELLKKLILNFFKD..NLKDHRAQY......KFYIALMKALENEKFSQEFKK.VMYGLYS---.---------.----------------.....
W7JPM3_PLAFO/202-298             ..............................l-KNIDKLCD..................ELLIYL.YKKNEVNTNNY............LRKYDEFKNKFDQF.LLNVNKYELLKKLILNFFKD..NLKDHRAQY......KFYIALMKALENEKFSQEFKK.VMYGLYS---.---------.----------------.....
A5K7Z6_PLAVS/255-376             ...............................VKYLDKLYD..................EVLKTT.DAKDEIHVPPF............HSKYNDFRKKYE-F.TMNEREYQIVKNLFDAFFKK..DGNPSPA--......DAVSFFKKMLNDPNVQKEFDN.FVHGLYGFAK.RHNYLRGER.MTDTKLYDELLKNVVN.....
B3L8N7_PLAKH/265-386             ...............................VKYLDKLYD..................EVLKGE.DGKNGIHIPEF............HSKYNDFRKKYE-L.TMNEQEYQMMKKLFDAFFKK..GESTN--AV......CPLEFFKKVLNNMSLQEEFDN.FQHGLYGFAK.RHNYLRGEK.TTNEKLYHDLLKNIIN.....
Q8IDY0_PLAF7/152-276             ..............................l-KRMDEVFD..................DVLKHL.NKEDKVVTDEN............KNKYNEFKKEFDIF.TMNVSEYEIMKNLLITFSKK..IDENNQIQT......KIENIFNKALKDNKYKEQFKN.FIYGLYSFAK.RHNYLIVNK.TNDTTLHKDLFENALN.....
A5K7Z7_PLAVS/259-380             ...............................VKYLDKLYD..................EVLKTT.DAKDEIHVPPF............HSKYNDFRKKYE-F.TMNEREYQIVKNLFDAFFKK..DGNPSPA--......DAVSFFKKMLNDPNVQKEFDN.FVHGLYGFAK.RHNYLRDER.MNLTDAHKSLFVNTL-s....
W7JQ58_PLAFO/152-276             ..............................l-KRMDEVFD..................DVLKHL.NKEDKVVTDEN............KNKYNEFKKEFDIF.TMNVSEYEIMKNLLITFSKK..IDENNQIQT......KIENIFNKALKDNKYKEQFKN.FIYGLYSFAK.RHNYLIVNK.TNDTTLHKDLFENALN.....
Q4Y1Q1_PLACH/1-120               ...............................--YTDDFFN..................SVIANI.---NENDNGDY............KDKYEDFKSKYDNIiAINQKEFEIFSKLIEGFMQS..NKDMNLSSD......YLYEVLTKALSDKAFKAEFKE.FMNSMYNFIK.KKH--EGKTlSENDKQYMALFENVL-t....
W7JPL9_PLAFO/71-194              ...............................IKYMDKLCD..................DVLTEL.KEKDNVDNNMN............HSKYNNLKKEFSTF.TMNQNECDLIKKLIITFSQE..--NVEMKRD......SIKEIFLKALDDKKYREVFKN.FMYGVYSYAK.RHNYLDIEKmEKNERAYKKLFENTLN.....
Q8IDX9_PLAF7/252-375             ...............................VKYLDLLYD..................ELLTNS.EGKHQVHFGEN............HKKYNIFRKHYDNF.VINQKEYDIIKKLLNSIFRD..-NNENEKMK......NLVSIFQKALNDKKFHDQFKN.FIYGIYGFAK.RHSYLRNEK.IQNDSEYKEFFENAV-d....
Q8IDX8_PLAF7/215-346             ..............................l-YNLGDVFN..................HVVDIS.NKKNKINLDEY............GKKYTDFKKEYEDF.VLNSKEYDIIKNLIIMFGQE.dNKSKNGKTDivseakHMTEIFIKLFKDKEYHEQFKN.YIYGVYSYAK.QNSHLSEKK.IKPEEEYKKFLEYSFN.....
Q8IDY4_PLAF7/171-294             ...............................IKYLDNAYD..................EVLKEM.NLSKNSDNEKY............RSRFDNFKQGFENL.ILNQNEYELIKRLILAFSNQ..EESGTNKKN......HIVNMLKKALEEEKFSDEFKN.FIYGIYAYAK.KHNYLRLID.-SNRDIYKNVFENATN.....
A5K7Z1_PLAVS/257-379             ...............................VKYLDKLYD..................DVLATQ.DSANGIDVPPF............HSKYNDFRKKYE-F.KMNDSEYKIMKNLFDVSFKK..-EGQQSSAA......CLVNVFKKVLDDEHLQKEFDN.FVHGFYGFAK.RHNYLRGER.MANENLYKDIFKNVVN.....
W7K1Q0_PLAFO/171-294             ...............................IKYLDNAYD..................EVLKEM.NLSKNSDNEKY............RSRFDNFKQGFENL.ILNQNEYELIKRLILAFSNQ..EESGTNKKN......HIVNMLKKALEEEKFSDEFKN.FIYGIYAYAK.KHNYLRLID.-SNRDIYKNVFENATN.....
B3L8P0_PLAKH/253-376             ...............................IHHFDLLYD..................NLLAGE.NKKNMMDEGEH............HSAYNNFRKQYDQL.ILSQTEYDICLKLLDTMLSN..GMVEEAKKN......ALKETFKKAMYDKDYGEKFKN.LISGVYAFAK.RNNFLDENK.VKGQD-YNKLFDYIC-s....
Q8IDY5_PLAF7/331-454             ...............................IKYMDKLCD..................DVLTEL.KEKDNVDNNMN............HSKYNNLKKEFSTF.TMNQNECDLIKKLIITFSQE..--NVEMKRD......SIKEIFLKALDDKKYREVFKN.FMYGVYSYAK.RHNYLDIEKmEKNERAYKKLFENTLN.....
W7K0P1_PLAFO/60-196              kdnlnffnnsleeaqkslldqpniststqgs---------..................------.-----ENNTSG............VSTNNNLTNPNDPT.QLNEQECQSIKKFIKELLSA..ATNDEHVNT......PFSTTFKNALEKDEFRDSITK.LTEALCGHTKdNHNNLRGTS.QNDSDYLHSVYDKA--ls...
Q4YB69_PLABA/1-123               ...............................IKYLDTIYD..................EILTNS.ENKNLINDNEN............HSKYREFKKKYDNF.AITPKESEIIKDLLIKMFVT..--NSNNKLN......ELLAVFKKALHDNKFAEELNN.LISGIYAFSK.RHNYLVTEK.EEYKEKYEKLYENIS-k....
A5K7Z8_PLAVS/1-73                ............................mie---------..................------.-----------............--------------.----RGCQVGKSLFDAFFEG..N----SNEC......CPSEFFKKVLNDAGLQKEF--.-----YSFVK.LYNYLMGER.VENENLHDELLKNV--si...
Q8IDY1_PLAF7/60-196              kdnlnffnnsleeaqkslldqpniststqgs---------..................------.-----ENNTSG............VSTNNNLTNPNDPT.QLNEQECQSIKKFIKELLSA..ATNDEHVNT......PFSTTFKNALEKDEFRDSITK.LTEALCGHTKdNHNNLRGTS.QNDSDYLHSVYDKA--ls...
A5K7Z0_PLAVS/322-445             ...............................IKYLDKLYD..................EVLTTS.DNTSGIHVPDY............HSKYNTIRQKYE-Y.SMNPVEYEIVKNLFNVGFKN..DGAASSDAT......PLVDVFKKALADEKFQAEFDN.FVHGLYGFAK.RHSYLSEAR.MKDNKLYSDLLKNAI-s....
W7JQ54_PLAFO/433-575             ...............................QKHNQDLYNikknndlpqyeesnktykKIFSNEhEPRPMITTSRY............ENKISN-DNNNNNY.NLNEQERKLIKNMIDIFIYTykLNYTNSK--......SISKLFKNNLLKKNFRTYFTN.YIYTLFNYGK.TYNFLTPYN.KDNDHMYRQLFDEAVQ.....
W7K1Q5_PLAFO/1-52                ...............................---------..................------.-----------............--------------.--------------------..---------......----MFKKILSDDQYMNDFKIfFILYLYSYAK.KYSYLKDAE.-NSRELYKNVYKNTI-g....
A5K7Z3_PLAVS/244-367             ...............................IKYLDKLYD..................EVLTTS.DNTNGIHVPDY............HSKYNTIRQKYE-Y.SMNPVEYEIVKNLFNVGFKN..DGAASSDAT......PLVDVFKKALADETFQAEFDN.FVHGLYGFAK.RHNYLSEAR.MKDADRYTNLLKNAI-s....
A5K7Z4_PLAVS/283-403             ...............................MEYVGNLHS..................DVGPTE.GSANQISPPSVdek.....gkedGDKYKSASQDGG--.------NSVGINNFGGCFQG..---GNSNGI......CPLDIFKKVLEDENFLQEFDS.FIHNLYGSSK.NNTPWGGDK.MGNENLYMDLFTNAL-s....
Q4XIX6_PLACH/1-82                ..............................i---------..................------.-----------............--------------.--TPKEAEIIKDILVKMFVT..--NPDNKVK......ELLVVFKKALHDKEFAEEFNN.LISGIYAFSK.RNNHLVIDQ.KEYKDKYNKLYEHIS-n....
A5K7Y9_PLAVS/247-369             ...............................VKHVDTLCD..................ELLAGE.NKKNVLDEGED............HSQYNIFRKQYDKM.VLNKTEYNISLKLLDTMLTN..GQVEREKKN......TLIKTFKKALYDKQYSEKLRN.LISGVYAFAK.RNNFIDGDK.VKEGD-YSKLFEYI--g....
Q7RMN1_PLAYO/188-310             ...............................IKYLDTIYD..................ELLTNS.ENKNLINNNEN............HNKYSEFKKRYDNF.ALTPKESEIIKDLLTKMFVT..--NSDNKLN......ELLVVFKKALHDKEFAEELNN.LISGIYAFSK.RHNYLVTEK.DEYREKYEKLYENIS-k....
Q4YB67_PLABA/208-327             .............................na--FLGTIFD..................EILNEQ.NHNEQVHTTQY............HSKYNSLKSECD-F.AMNLEEYAIAKKIISSYFKS..GTAENPI--......YLYDILIKSLNDEEYKKHFKN.FIYGVYSFAK.KYNYLSESR.LEEEN--NNFI-----asvlk
Q4XQ10_PLACH/1-81                ...............................---------..................------.-----------............-------------F.AMSLEEYEIAKKLISTYFNG..---TTENPI......HLYDILIKAITDEEYKKHFKN.FIYGIYSFAK.KHNYLSTAR.LAEEN--SQFISNVLN.....
A5K7Z5_PLAVS/322-445             ...............................IKYLDKLYD..................EVLTTS.DNTSGIHVPDY............HSKYNTIRQKYE-Y.SMNPVEYEIVKNLFNVGFKN..DGAASSDAT......PLVDVFKKALADEKFQAEFDN.FVHGLYGFAK.RHSYLSKER.MGDTTRYSDLLKNAI-s....
B3L8N6_PLAKH/145-270             ..............................l-NYADDLYE..................DILSSL.SKKGGEEGTNY............DDKYNEFKKEYDRFiSLSKDEYEIIGKLIDAFSMY..NDAISEDTD......SVYQAIKKSFTDKKFKQEFKD.FMNGIYTYTQ.KKHNIRGSQ.TEDIKKYLMLFQNIIN.....
W7KB65_PLAFO/252-375             ...............................VKYLDLLYD..................ELLTNS.EGKHQVHFGEN............HKKYNIFRKHYDNF.VINQKEYDIIKKLLNSIFRD..-NNENEKMK......NLVSIFQKALNDKKFHDQFKN.FIYGIYGFAK.RHSYLRNEK.IQNDSEYKEFFENAV-d....
Q7RMM9_PLAYO/1-96                ...............................---------..................------.-----------............---YEDFKNKYDNViAIDEKEFEIFSKLVEVFMKN..HQDFSFNSN......FLYELLTKALSDQGFKTEFKE.FMNNMYNFVK.KKQEGKPMT.-ENDKIYMTLFENVL-s....
B3L8N8_PLAKH/297-411             ...............................INYLDELYD..................EIITTP.DIKKKMQNSSY............KTKYKL--------.SLNPAEYQIVKKLFELGFGN..-ENESSAGT......SLVEVFKKVLDDEKFQKEFDN.IVQGFYGFAK.RHNYISQEQ.MNNTS-HTNLLKNAIN.....
A5K800_PLAVS/276-412             ...............................MKHMSSFLN..................GLLTNQsNNKKEIFFHPYygpyfnhggyynYDPYYNYAPAYNPF.VSQARDYEVIKKLLDACFNK..GEGADPNVP......CIIDIFKKVLDDERFRNELKT.FMYDLYEFLK.KNDVLSDDE.-KKNELMRFFFDNAFQ.....
Q7RMN0_PLAYO/196-315             .............................ta--FLGAIFD..................EILKEQ.HHDDDVHSTEY............HSKYNSLKNECD-F.PMNLEEYNIAKKLISSYFQS..GSTENPI--......YLYDILLKSLKDEEYKKHFKN.FIYGIYSFAK.KYNYLSATR.LAEAN--SQFIPNVL-k....
W7JPM7_PLAFO/215-346             ..............................l-YNLGDVFN..................HVVDIS.NKKNKINLDEY............GKKYTDFKKEYEDF.VLNSKEYDIIKNLIIMFGQE.dNKSKNGKTDivseakHMTEIFIKLFKDKEYHEQFKN.YIYGVYSYAK.QNSHLSEKK.IKPEEEYKKFLEYSFN.....
#=GC seq_cons                    ................................KahDplaD..................-lLpp..ptcstlpssph............csKYssh+pca-.a.shN.pEY-IlKcLlpshhps..ttsssppts......plhplFKKuLpDccapccFcN.FlaGlYuFAK.++NYLpsp+.hpspchYppLacNsl......
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