GenomeNet

Database: Pfam
Entry: MTD
LinkDB: MTD
Original site: MTD 
#=GF ID   MTD
#=GF AC   PF01993.15
#=GF DE   methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase
#=GF AU   Enright A, Ouzounis C, Bateman A
#=GF SE   Enright A
#=GF GA   25.00 25.00;
#=GF TC   26.70 332.00;
#=GF NC   21.70 20.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   7852356
#=GF RT   Cloning, sequencing, and transcriptional analysis of the
#=GF RT   coenzyme F420- dependent
#=GF RT   methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase gene
#=GF RT   from Methanobacterium thermoautotrophicum strain Marburg and
#=GF RT   functional expression in Escherichia coli. 
#=GF RA   Mukhopadhyay B, Purwantini E, Pihl TD, Reeve JN, Daniels L; 
#=GF RL   J Biol Chem 1995;270:2827-2832.
#=GF DR   INTERPRO; IPR002844;
#=GF DR   SCOP; 1qv9; fa;
#=GF CC   This enzyme family is involved in formation of methane from
#=GF CC   carbon dioxide EC:1.5.99.9. The enzyme requires coenzyme F420
#=GF CC   [1].
#=GF SQ   44
#=GS K4ME31_9EURY/2-277      AC K4ME31.1
#=GS U6EAV6_9EURY/3-276      AC U6EAV6.1
#=GS H1YWR8_9EURY/3-280      AC H1YWR8.1
#=GS MTD_METAC/5-279         AC Q8THT2.1
#=GS A0B7C4_METTP/2-273      AC A0B7C4.1
#=GS E3GZ78_METFV/3-276      AC E3GZ78.1
#=GS F7XNL9_METZD/2-278      AC F7XNL9.1
#=GS N0BIS0_9EURY/2-272      AC N0BIS0.1
#=GS MTD_METJA/3-277         AC Q58441.1
#=GS D7EB48_METEZ/2-277      AC D7EB48.1
#=GS MTD_METPE/3-280         AC B8GJQ7.1
#=GS Q46DH9_METBF/2-276      AC Q46DH9.1
#=GS MTD_META3/3-277         AC A6UWS1.1
#=GS E1RKC0_METP4/3-280      AC E1RKC0.1
#=GS D5EAK3_METMS/2-276      AC D5EAK3.1
#=GS L0KTR5_METHD/2-274      AC L0KTR5.1
#=GS G7WNZ3_METH6/2-272      AC G7WNZ3.1
#=GS D5VSM6_METIM/2-274      AC D5VSM6.1
#=GS R9SJF9_9EURY/3-276      AC R9SJF9.1
#=GS F0T7A4_METLA/3-276      AC F0T7A4.1
#=GS F4BZ98_METCG/2-272      AC F4BZ98.1
#=GS L0HKS1_METFS/3-279      AC L0HKS1.1
#=GS MTD_METMP/3-277         AC Q6M099.1
#=GS MTD_METST/3-276         AC Q2NHQ2.1
#=GS MTD_ARCFU/3-273         AC O29544.3
#=GS J0RY20_9EURY/3-280      AC J0RY20.1
#=GS MTD_METKA/4-283         AC P94951.3
#=GS MTD_METKA/4-283         DR PDB; 1U6I D; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQF G; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6I C; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1QV9 C; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQE F; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6I B; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6J G; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6J B; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQZ D; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQE A; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQF E; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1QV9 A; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6J K; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQF L; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6I F; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQZ E; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6K B; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6I A; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6K C; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQF K; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQE E; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6I K; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1QV9 B; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6I J; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQE D; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQF D; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6I E; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6J F; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6J D; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6J C; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQF C; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQZ B; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6J J; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQF J; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6I I; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQZ A; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6J L; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6J I; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQF A; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6I G; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQE B; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6I L; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQZ F; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQZ C; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6J A; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6I H; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQF F; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6J H; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQF B; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6K A; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQF H; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQE C; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 1U6J E; 4-283;
#=GS MTD_METKA/4-283         DR PDB; 3IQF I; 4-283;
#=GS F6D7B4_METPW/3-276      AC F6D7B4.1
#=GS F2KNE0_ARCVS/1-272      AC F2KNE0.1
#=GS MTD_METTH/3-276         AC Q50501.3
#=GS MTD_METHJ/3-280         AC Q2FU89.1
#=GS D2RET8_ARCPA/1-253      AC D2RET8.1
#=GS MTD_METMA/5-279         AC Q8PXV8.1
#=GS MTD_METB6/3-279         AC A7I5N7.1
#=GS D3E118_METRM/3-276      AC D3E118.1
#=GS MTD_METLZ/3-280         AC A2SPK1.1
#=GS D7DR53_METV3/3-277      AC D7DR53.1
#=GS Q0W2P5_METAR/3-274      AC Q0W2P5.1
#=GS A0A0A7GCQ3_9EURY/2-272  AC A0A0A7GCQ3.1
#=GS D1YY63_METPS/3-275      AC D1YY63.1
#=GS Q12XF4_METBU/2-273      AC Q12XF4.1
#=GS MTD_METMJ/3-280         AC A3CSZ5.1
#=GS MTD_METS3/3-275         AC A5UMI1.1
#=GS D3RXG7_FERPA/2-272      AC D3RXG7.1
K4ME31_9EURY/2-277                 a-KIGFIKLGNLGMSQVIDLVQDEIAAREGISVRVFGTGPKMGKDEAA-ATAE.L...K..NWGADFYVMISPNASAPGPTAAREIY--KDVP..CIIISDGPTKKED.rEALEAAGFGFIIMTVDPLIGAKTEFLDPVEMASFNSDAMKVLSTCGVVRLIQEELDKVTTMVDEGKsgkELELPHIVAKPEKCIERAGFSNPYAKAKGLAALHMADMVAKINFPACFMMKEIEQVTLTTAAGHEMMRAAAQLAIEAREIEKANDSVFRQPHAKK.GgRLMTKTKLYEKP-q..
U6EAV6_9EURY/3-276                 .VKIGVIKSGNIGTSPVLDLVLDERADRPNIDVRGVGSGAKMNPEQVEEVVPK.I...M..DFDPDFVIFISPNPGAPGPAKARELLSEMDIP..ALIIGDAPGMGKR..EEMDEQGLGYIVVLGDPMIGARREFLDPTEMASFNADVIKVLAATGAYRVVQETIDEMIAACEAGK...DIELPKVVIDAATATEAAGFANPYAKAKAMAAYEMAAKVGDIDLKGCFMVKDMEKYIPIVASAHELIAAAAQLATEAREIEKANDTVLRKPHGSK.G.QTMSKTVLVSKPE...
H1YWR8_9EURY/3-280                 .VKVGIAKLGNIGSGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVDN.M...K..AWGPDFCIVVSPNGVLPGPKGAREALAAAGIP..CVVITDDITSKKDdfAALKESNFGYIIMKADSMIGARREFLDPVEMSDYNGNLIKVLTITGAFRKLQLALDAVIDQVKAGKkgaELELPKIVMTSDKAVA-DEFTNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGHENYTPIVASAHEMMRSATLLCDEAREIEKGCDGVIRMPHKND.G.EIVKKTALISKP-w..
MTD_METAC/5-279                    .VNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMGPADAA-DTES.F...K..QWNADFVVMISPNAAAPGPTAAREIW--KDVP..CIVVSDGPTKKEA.rEALEQEGFGYIILPVDPLIGAKREFLDPVEMASFNSDAMKVLSSCGVVRLIQEELDRVTEQVASGKsgeDLELPHIFAKPEKCVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEVEQVCLTAAAGHEIMGAAAILATQAREIEKSNDTVFRQPHAKN.G.TLLKKVKLYEKPE...
A0B7C4_METTP/2-273                 .FKIGFIKLGNIASSLVVDLALDEIAERTEIESKVVSHGPKMSRGEGERLAEE.M...R..AWGPQMVVVVSPNAATPGPTAARSML--KGIP..LIVISDGPTKKEA.rDAMETEGFGYIILPMDPLIGAKREFLDPAEMAIFNADALKVLSICGAVRLVQEEIDRAIASVAAGS...-PQLPHILATPELCAERMDFANPYARAKAIAALYMAQTAASIDAQACFRLKELEAIALAAAAGHEVIRAAARLADEARELEKSGDTVSRKPHARS.G.DLLVKRKLLEKP-a..
E3GZ78_METFV/3-276                 .VKIGVIKCGNIGTSPVIDLLLDERADRPNIDVRVIGSSAKMNPEQVEDVVPK.M...L..DMDRDLVIFISPNPGAPGPAKARELLSESDVP..SIIIGDAPGKRVK..DEIEKQGLGYIIVEADPMIGARREFLDPTEMASFNADVIKVLACTGAYRLIHKTLDDLISDLEAGK...EIELPKLIIDSEKAVEAGEFENPYAKAKAMAAYEIAAKAADLDVKGCFMVQDPEKYIPIVASAHEMVSIAAKLASEAREIEKSNDTVKRTPHGKK.G.ELLEKVELMAKP-k..
F7XNL9_METZD/2-278                 a-KIGFIKLGNLGISQVIELVQDEIAAREGISIRVFGTGPKMGKDEAA-STEQ.F...KdmSWDADFYVIISPNASAPGPTAAREIW--KDVP..CIIVSDGPTKKDD.rQALEEAGFGYIILKVDPLIGAKTEFLDSVEMASFNSDAMKVLSTCGVVRLIQEELDKVVEQVDAGKsgsDIELPHILAKPEVCVERAGFENPYAKAKALASLFMAEKVAQINFPACFMMKELEDVALTTATGHEMMRAAAELAVQAREIEKINDTVSRHPHSKK.G.KVLSKTRLFEKP-a..
N0BIS0_9EURY/2-272                 .VKVGVVKMGAIGTALLVEYLLDERADREDITVRVVTSGAKMQPEEAE-IVEK.M...K..EFDPDLVIVVSPNAALPGPKAAREAF--EGKP..VIVISDAPAKKAK..EEFEEKGFGYILVNADSMIGARREFLDPTEMALFNSDVVKVLAATGAFRLVQEEIDKVIEALKEGK...TPELPKIVVTAEKAVKAGNFKNPYAKAKAMAAYYIAEKVADIDVKGCFIERDPEKYIPLVAAAHEMMRVAAIEADRAREIEKGGDSVYRNPHAKD.G.KILSKTSLMEKP-q..
MTD_METJA/3-277                    .VKIGIIKCGNIGMSPVVDLALDERADRKDIAVRVLGSGAKMDPESVEEVTKKmV...E..EVKPDFIIYIGPNPAAPGPKKAREILSQSGIP..AVIIGDAPGLRVK..DEMEQQGLGYIIIKCDPMIGARREFLDPVEMALFNADVIRVLAGTGALRIVQEAIDKMIDAVKEGK...EIELPKIVITEQKAVEAMEFTNPYAKAKAMAAFTIAEKVGDVDVKGCFMTKEAEKYIPIVASAHEMIRYAAKLVDEARELEKAMDAVSRKPHHPE.G.KRLSKKALMEKPE...
D7EB48_METEZ/2-277                 .VKVGFIKLGNLGMSQVVDLLEDEIAAREGITTRVYGTGPKMSKEDAADTEAF.K...E..EFDPDFVIIISPNASTPGPTEARQLW--KDKP..CLIISDGPTKKDD.rQAIEDEGFGYIILPVDPLIGAKTEFLDPEEMASFNSDVMKVLSTCGAVRLVQEELDKLTSQVDEGKsgdEIEMPHIYAKPQTCIERSGFSNPYAKAKALAALHMAEKVSQINLPACFMLKDLEEVAFTAATGHEMIRAAAELAVEAREIEKTNDTVLRKPHSKK.G.KVLSKTKLYEKP-q..
MTD_METPE/3-280                    .VKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVST.M...K..AWEPDFCIVVSPNGVLPGPVGARDELLKAGIP..CVVITDDITTKKEgwEALKASSFGYIIMKADAMIGARREFLDPVEMADFNGNLVKVLALTGAFRKLQTELDKVIDQVKEGKkgaDLVLPKVVMTSDKAVD-GEFSNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWEKYIPIVASAHEMMRQAAALGDEAREIEKAGNGIIRKPHKKD.G.TIVSKITLISKPE...
Q46DH9_METBF/2-276                 .VNIGFIKMGNLGMSQVINLVQDEIAAREGITVRVFGTGAKMSPAEAA-ASES.F...K..QWNADFVIIISPNAAAPGPKAAREIW--KDVP..CIVVSDGPTKKEA.rEALENNGFGYLILPVDPLIGAKREFLDPVEMASFNSDAMKVLSVCGVVRLVQEELDKVTDQVASGKsgkELELPHIFAKPEKCVEYAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAASQLAIQAREIEKSNDTVLRQPHAKN.G.TLLKKVKLYQKPE...
MTD_META3/3-277                    .VKIGIIKCGNIGMSPLIDLALDERADRTNIDVISIGSGAKMGPNQVVEVTTKmV...E..DIKPDFIIYVGPNPAAPGPAKAREILSASDIP..SVIIGDAPGIKAK..DKMAEEGLGYILIKCDPMIGARRQFLDPVEMAMFNADVIRVLAGTGAARVVQNAIDDIVEAIEAGN...EIELPKIVVTDAKSVAAAEFSNPYAKAKAMAAFAMAEQVANIDVKGCFMTKEMEKYIPIVASAHEMIRTAAKLVDEARELEKATDSVSRKPHGAD.G.KRLNKTKLMEKPE...
E1RKC0_METP4/3-280                 .VKVGIAKLGNIASGVMAELLLDERADREDMETFMATSGTKLQEKDIDRVVEN.M...K..AYGPDFCIVVSPNGVLPGPKGAREALAAAGIP..CVVITDDITTKKDefAALKETSFGYIIMKADAMIGARREFLDPIEMADYNGNLVKVLAVTGAFRKLQIALDEVIDQVKEGKkgaDLVLPKIVMSSDKAVE-GEFTNPYAYAKARAAYEMAQSVAGINVKGCFMTKGHENYTPIVASAHEVMRQAMLLCEEAREIEKSCDGVIRKPHKSD.G.TRVEKVKLIDKP-w..
D5EAK3_METMS/2-276                 .VKVGFIKLGNLGMSQVIDLVQDEIAAREGITTRVFGTGPKMDKETAA-STEE.L...K..AWDPDFVVMISPNASAPGPKSARELW--KDYP..CIVVSDGPTKKDD.rQALEDAGFGYIIMTVDPLIGAKTEFLDAVEMASFNSDAMKVLSTCGVVRLLQEELDAVTAQVDEGKsgaDLELPHILAKPQKCIERAGFNNPYAKAKGLAALHMASKVAEVNMPACFILKEIEDVTLTAATGHELMRAASQLAIEAREIEKANDSVFRQPHSKK.G.FQLQKTKLYEKP-q..
L0KTR5_METHD/2-274                 a-KIGIIKLGNLGMSQVVDLVQDEIAAREGITVRVFGTGPKMGKDEAA-ATAD.L...K..KMEADFYVMISPNSSAPGPTAARELY--KDVP..CIIISDGPTKKED.rEALQQAGFGYIIMTVDPLIGAKTEFLDPVEMASFNSDAMKVLSTCGVVRLIQEELDKVAALVDAGE...PIQLPHILAKPEVCIERAHFNNPYAKAKGLAALHMADMVAKINFPACFMMKELEQVALTTAAGHEMMRAAAQLAIEAREIEKANDSVFRQPHSKKgG.KQFQKTKLYEKP-q..
G7WNZ3_METH6/2-272                 .FKIGFIKLGNVASSLVADLALDEIAERTDVEVRSLSFGAKMTVKEAE-MSAE.L...K..GWGPQLVVIVGPNAATPGPTAARALY--RDVP..TIVISDGPSKKEA.rEALEAEGFGYIILPFDPLIGAKREFLDPAEMALFNSDALKVLSICGSVRLVQEELDGAMASIISGA...-PRLPTILSSPEGCTDRMAFRNPYARAKAIGALHMAQTVAGIDAAACFRLKELDRIALTAAAGHEVMRAAARLADEARELEKSTDSVSRRPHARS.G.AILAKTGLLDKPE...
D5VSM6_METIM/2-274                 .VKVGIVKCGNIGTSLVVDLALDERAER-DINVLVYGSGAKMNPESVEYVVKK.M...I..EEKPDLIIYIGPNPAAPGPRKARELLSECKIP..SIIIGDAPGIKVK..DEMEKEGLGYILIKGDPMIGARREFLDPTEVALFNSDILKVLAVTGVVRLVQEEIDRVIEYIKEGK...EPELPRIVVDAEKAVERMEYSNPYAKAKAIASYNMAEEVANIDVKACFMVKEPERYIILAASAHELLRQAAKLADEARELEKATDMVSRKPHAKD.G.RILSKRKLLEKP-q..
R9SJF9_9EURY/3-276                 .VKIGIVKSGNIGASPVLELLLDERADRPNIDVRVFTSGAKMNPEQVEDVVPK.V...K..DFNPDFVMFSSPNPTAPGPAKARELLSEMDVP..AFIIGDAPGKRAK..DEMDEQGIGYIIVEADSMIGARREWLDPTEMSVFNSDLIKVLACTGAYRLIQNTIDGVIAQADAGE...EIELPKLVINAQKAVDAAGFTSPYAKAKAYAAYEMCAKVADLDMKGCFMMKNYEEFLPVVAAAHEMASAAAQLATEAREIEKANDTVLRTPHMSD.G.STGKKVNLISKPE...
F0T7A4_METLA/3-276                 .VKIGIIKCGNIGTSPVIDLLLDERADRPNIDTCVVGSGAKMNPEEIEKAVPL.M...L..EMDRDFVIFISPNPGAPGPAKARELLSAADVP..AIIIGDAPGLRSK..DEMDEQGLGYIIVKADPMIGARREFLDPTEMASFNSDVIKVLALTGAYRVVQNTIDAAVTAVESGE...TLELPKVVITRDKAVEAAAFGSPYAKAKAMAAYEIATKVADIDVEGCFMVRDAEKYIPLVASAHEMLGVAAKLASEARDIEKANDTVVRTPHGGK.G.QTLSKVALADKPE...
F4BZ98_METCG/2-272                 .FKIGFVKLGNIATSTAIDLSLDEIAERTDIEFKIISFGPKMTEKEGK-GAEE.L...K..AWQPQLVVISSPNAATAGPTAAREAY--RGIP..TIIISDGPSKKEA.rEALSAEGYGYIILPMDPLIGAKREFLDPAEMALFNSDALRVLAACGAIRLVEEELDRTIASIISGQ...-AKLPTILATPEKCAERMHFSNPYAQAKAMGALYMAQTVASIDAAACFRLKELKPIALTAAAGHEVMRAAARLADEARELEKSNDTVSRQPHART.G.ELMQKLSLLDKPE...
L0HKS1_METFS/3-279                 .VKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVSN.M...K..AWKPDFCIVVSPNGVLPGPTGAREELAKSGIP..CIVITDDVTTKKE.wEGIKTSSFGYIIMKADSMIGARREFLDPIEMADFNGNLVKVLAGTGAFRKLQVAIDQVIDQVKAGKkgaELVLPKIVMTTDKAVD-GEFTNNYALAKARAAHEIAMAVAGQNVKGCFMTKEWEKYIPIVASAHEMMKVAAALCDEAREIEKAGDTVLRQAHKKD.G.VLVRKNKLVAK--fd.
MTD_METMP/3-277                    .VKIGILKCGNIGMSPVVDLCLDERADRNDIDVRVLGSGAKMGPEQVEEVAKKmV...E..EIKPDFIVYIGPNPAAPGPKKAREILSAGGIP..AVIIGDAPGIKDK..DAMAEEGLGYVLIKCDPMIGARRQFLDPVEMAMFNADVIRVLAGTGALRVVQNAIDDMVFAVEEGK...EIPLPKIVITEQKAVEAMDFANPYAKAKAMAAFVMAEKVADIDVKGCFMTKEMEKYIPIVASAHETIRYAAKLVDEARELEKATDAVSRKPHAGA.G.KILNKCKLMEKPE...
MTD_METST/3-276                    .VKIGIVKVGNIGTSVLIDMILDERADREDIDVRTISSGAKMGKNQMDDVLPK.I...D..EYNPDVIIFISPDPGAKSPSSARETLSKKNIP..TIVIGDGPGERAI..GSMKEQGLGYIIVKADSMIGARREFLDATEMAVFNSDVLMVLSTTGVFRLIHKTLDKVIRDIDEDK...LYSLPELVITAENAVDAADFKNPYAKSKAIAAYSIACQVSSMNVRACFKTKDYHVYIPLVSAAHEMMSAASKLAYEAREIEKSNDTVVRTAHRRN.G.SILYGTSLND---nke
MTD_ARCFU/3-273                    .VKVGVLKMGAIGTALLVEYLLDERADREDIEVRVVTSGAKMQPEEAV-VAEK.L...K..EFDPDVVIVVSPNAALPGPKAAREAF--EGKP..VIVISDAPAKKAK..DELKEKGFGYILINADSMIGARREFLDPTEMALFNADVVKVLAATGAFRLVQEAIDKVIEDIKAGK...QPELPQIVVTAEKAVEAGKFSNPYAKAKAMAAFYIAEKVADIDVKGCFIEKDPEKYIPLVASAHEMMRIAAILADQAREIEKSNDTVFRNPHAKD.G.KILGKTQLMAKPE...
J0RY20_9EURY/3-280                 .VKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTN.M...K..AWGPDFCVVVSPNGVLPGPTGAREELAKAGIP..VVVITDDITTKKEqfDALKASTFGYIIMKADSMIGARREFLDPIEMADYNGNLVKVLALTGAFRKLQFELDKVIDQVKAGKkgaDLVLPKVVMTSDKAVE-GEFSNPYALAKARAAYEIASAVAGVNVKGCFMTKEWEKYIPIVCSAHEMMRQASVLCDEAREIEKAGDAVIRKPHKKD.G.VIVSKTALISKPE...
MTD_METKA/4-283                    a-KAIFIKCGNLGTSMMMDMLLDERADREDVEFRVVGTSVKMDPECVEAAVEMaLdiaE..DFEPDFIVYGGPNPAAPGPSKAREMLADSEYP..AVIIGDAPGLKVK..DEMEEQGLGYILVKPDAMLGARREFLDPVEMAIYNADLMKVLAATGVFRVVQEAFDELIEKAKEDEi.sENDLPKLVIDRNTLLEREEFENPYAMVKAMAALEIAENVADVSVEGCFVEQDKERYVPIVASAHEMMRKAAELADEARELEKSNDAVLRTPHAPD.G.KVLSKRKFMEDPE...
#=GR MTD_METKA/4-283         SS    E-EEEEEES--HHHHHTTGGGSTTS--SSEEEEEEEEET--SHHHHHHHHHHHHHHHHH..-SEEEEE-S-TTSHHHHHHHHHHHHSSS-EEE..EGGGGGGHHHHHH..-EEEEETTS------TTT--HHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTT---GGGS-E.EESGGGGGGSS--SSHHHHHHHHHHHHHHHHHHHHHHHHHHT---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT---B--B-TTSSB--BSS.T.---XXXXXXXXXX...
F6D7B4_METPW/3-276                 .VKIGVIKCGNLGTSPVIDLMLDERADRPNISVKSFGSGAKMGPEEIEEVVPK.V...A..DLDAAFVIFISPNPAAPGPAKARELLSAMDVP..AIIVGDGPGARVK..DEMNEQGLGYILVKGDPMIGARREFLDPTEMASFNADVIKVLAATGAYRCVQKTLDALIAAAEAGE...AIEVPKLVLTRDKAIAAAEFKNPYAKAKAMAAYTIAEKVADIDVEGCFMTKDAEKYIPIVASSHEMIAVAAKLAAEAREIEKANDTVLRTPHSGK.G.QLVSKTTLMSKPE...
F2KNE0_ARCVS/1-272                 m-RIGIIKLGAIATALLIDYMLDERADREDIDVRTITSGSKLRERDAE-IVDK.M...R..EFNPDLVIVASPNAALPAAKLARDALKAEGKP..VIVISDAPAKKVK..DELEAEGFGYILVNADSMIGARREFLDPTEMCLYNSDVIKVLAATGAFRAVQLAVDEAIESAKAGK...-PKLPRLIIDAEAAVNAGNFSNPYARAKAMAAYTIAEKVAAVTTKACFVEKDAEKYIPMVAAAHEMMRYAAKLAEEAREIEKSSDAVYRTPHAKD.G.RVLSKWGLMEKP-s..
MTD_METTH/3-276                    .VKIGIIRCGNIGTSPVLDLLLDERADRPNIDVCVVGSGAKMNPDEIERAVPT.M...L..EMDRDFVIFISPNPGAPGPAKARELLSEADVP..AMIIGDAPGLRVK..DEIEEQGLGYIIVKADPMIGARREFLDPTEMASFNSDVIKVLAFTGAYRVVQNTIDAMIADVEAGK...APELPQVVIDTDVAVEAAGYENPYAKAKAMAAYEIATKVADIDVKGCFMVQDPDKYIPIVASAHEMLAAAAKLAVEAREIEKANDTVLRTPHGKE.G.ETLSKTDLLAKPE...
MTD_METHJ/3-280                    .VKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTN.M...K..AWGPDFCIVVSPNGVLPGPKGAREALAAAGIP..CVVITDDITTKKEewEALKASEFGYVIMKGDSMIGARREFLDPIEMADYNGNLIKVLSITGAFRKLQVALDEVIDQVKAGKkgkDLALPKLVMTSDKAVE-GEFSNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGFENYTPIVASAHEMMRQAMLLCEEAREMEKATDAVIRKPHKND.G.TRVAKKTLISKPE...
D2RET8_ARCPA/1-253                 m-RIGIAKLGAIGSAVLLEYCLDELAMRGDIETFVVSSGSKIKVEVLEE----.L...E..KRDFDLKIVTCPN--------AEKFLKDVNLSdrVIVITDRASK---..DWLDSLNWGYIVVKADAMIGARREFLDPTEMVLYNSDLLKVLAVTGIIRLLQYEINRALK------...EDYLPKVVVDYNTAVKFAGFCNPYARAKAIASYIIAENISKITHKACFVEKDAENYITLCATAHEMMRIAGKLADEAREIEKSNDSVLRTPHSKS.G.EILKKVGLYD---v..
MTD_METMA/5-279                    .VNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAA-DTES.F...K..QWNADFVVIISPNAAAPGPTAAREIW--KDVP..CIIVSDGPTKKEA.rEAFEQEGFGYIILPVDPLIGAKREFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVTEQVASGKsgkDLELPHIFAKPEKCVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAAAQLANQAREIEKSNDTVSRMPHAKN.G.AVLKKVRLYEKPE...
MTD_METB6/3-279                    .VKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVSN.M...K..AWKPDFAIVVSPNGVLPGPTGAREQLAAAGIP..VIIITDDVTTKKE.wEEVKNSKFGYIIMKADSMIGARREFLDPIEMADFNGNLVKVLAITGAFRKLQLALDKVIDQVKAGKkgtEIELPKIVMTTDKAVD-GEFTNDYALAKARAAHEIAIAVAGQNVKGCFMTKEWEKYIPIVASAHEMMRIAAVLCDEAREIEKAGDGILRQPHKKD.G.VLVRKTKLVAK--fe.
D3E118_METRM/3-276                 .VKIGIVKSGNIGTSPVLDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPK.L...D..QFDPDFCIFISPNPGAPGPARARELLSEKDLP..AIIIGDAPGKGKK..DEMDEQGLGYIIVMSDPMIGAKREWLDPTEMAIFNADILKVLAETGALRLVQKTLDAVIAAADAGE...EIELPKLIVTAEKAVEAAGFANPYAKAKAIAAYEMAGAVAGLDMKGCFMTKGFENFIPLVAAAHEIASAAAKLAQEAREIEKSNDTVLRTPHMKE.G.NLGCKVDLISKP-v..
MTD_METLZ/3-280                    .VKVGVAKLGNIAAGVMAELLLDERADREDMMTFMATSGTKLQKEDVDRVVSN.L...K..AWQPDFAIVVSPNGVLEGPVGAREDLKAAGIP..TIVITDDVTTKKEgwEALKASGFGYIIVKADAMIGARREFLDPVEMADYNGNLVKVLALTGAFRKLQLELDKVIDQVKAGKkgaELELPKLVLNSDNSTK-GEFTNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWTDYVPIVASAHEMMRAAANLCDQARELEKGCDGVIRKPHKKT.G.EIVSKVALISKPE...
D7DR53_METV3/3-277                 .VKVGIIKCGNIGMSPLVDLSLDERADRNDIDVRVVGSGAKMGPEQVEEVTKKmI...E..DIKPDFVLYIGPNPAAPGPKVARELLSAADIP..AVIIGDAPGIKDK..DAMAEQGLGYILIKCDPMIGARRQFLDPVEMSMFNADVVRVLAGTGAVRVVQNAIDAMIYAVEEGK...EIELPKIIVTDAKAVAAAEFSNPYAKAKAMAAFVMAEKVADIDVKGCFMTKEMDKYIPIVASAHEMIRYAAKLVDEARELEKATDGVSRKPHAGP.G.AILNKSKLMEKPE...
Q0W2P5_METAR/3-274                 .VRVGIVKLGNIGTSRFIDLVLDERADR-DIYVRTVGAGAKMGEAEAE-EMKK.I...I..DFKPQFCIVISPNATVPGPTKAREMLKEAGIP..TIVISDSPVLKIK..DDLKAKGFGYFVVKCDPMIGARRQFLDPTEMVLFNADVLKVLANTGVVRLIQKELDAVIEGFAAGQ...TPALPQIVISADKAVAAAGYKNPYAKAKAMAAFVAAEKVADIDLQGCFMQKEMEQYIPTVASAHELLREAAKLSDEARELEKATDAILRTPHAAD.G.KVLSKTQLMLKPE...
A0A0A7GCQ3_9EURY/2-272             .VKVGVLKMGAIGTALLVEYLLDERADRGDIEVRVVTSGAKMQPEEAV-VAEK.L...R..EFDPDVVIVISPNAALPGPKAAREAF--EGKP..VIVISDAPAKKAK..EEFEEKGFGYILINADSMIGARREFLDPTEMALFNSDVVKVLAATGAFRIVQEELDRVIEAIKKGE...TPELPKMVITAQKAVKAGNFQNPYAKAKAMAAYFIAEKVADIDVKGCFIERDPEKYIPLVASAHEMMRVAALLADQAREIEKCNDTVYRTPHSKE.G.EILKKFELMGKPE...
D1YY63_METPS/3-275                 a-RVGIVKLGNLGTSRYIDLILDERADR-DIYVRTVGTGAKLGEAEADEAVAK.I...L..EFKPQLCIVISPNGALPGPTKAREAIKAAGVP..TIAISDVPMMKVK..DDLKAKGLGYFIVKCDSMIGARRQFLDPTEMVLFNADMTKVLAETGVVRLIQTELDKCIDMINAGQ...PVTVPQIVIDAAKAVPMAGYTNPYAQAKAFAAFAAAEKVGDLDLLGCFMQKEMEQYIITVASAHELLRTAALLCDQARELEKGGNSIKRTPHAAD.G.KVLSKTTLVSKPE...
Q12XF4_METBU/2-273                 a-KIGFIKLGNLGMSQVIDLVQDEIAAREGISVRVFGTGPKMGKDEAA-ETAA.L...K..EWDADFYVMISPNSSAPGPTAAREIY--KDVP..CIVISDGPTKKDD.rQALEDAGFGYIIMTVDPLIGAKREFLDSVEMASFNSDAMKVLSTCGVVRLIQEELDIVTAQVDEGK...EIVLPHILAKPEKCIERAGFSNPYAKAKALAALHMADKVAQINFPACFMMKEIEQVTLTTATAHEMMRAAAQLAIDAREIEKSNDTVLRQPHAKK.G.NILSKTALYEK--qq.
MTD_METMJ/3-280                    .VKVGIAKLGNIASGVMGELLLDERADREDMITFMATSGTKLQPEDIERVVSN.M...K..AWGPDFCIVVSPNGVLPGPTQAREDLAAAGIP..CIVITDDVTTKKEqfEALKASNFGYIIMKADAMIGARREFLDPIEMADYNGNLVKVLALTGAFRKMQMELDKVIDQVKAGKkgaDLALPKVVMTSDKAVD-GEFSNPYALAKARAAYEIAQSVAGVNVKGCFMTKEWEKYIPIVASAHEMMRQAMLLCEEARTLEKGVDAVIRKPHKKT.G.EIVSKTALISKPE...
MTD_METS3/3-275                    .VKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPK.V...D..QFDPDFCIFISPNPGAPGPAKARELLSEKDIP..AIIIGDAPGKGKK..DEMDEQGLGYIIVMSDPMIGAKREWLDPTEMAIFNADILKVLAETGALRLVQNTIDGVIDGAAAGN...-IELPKLIITAEKAVEAAGFENPYAKAKAIAAYEMAGAVANLDMKGCFMTKGFENFIPLVAAAHEMAASAAALADEAREIEKGNDSVLRTPHMKE.G.NTGCKTDLISKPE...
D3RXG7_FERPA/2-272                 .VKVGILKMGAIGTALLVEYLLDERADREDIEVRVVTSGAKMQPEEAK-IAEK.L...K..EFDPDLVLVVSPNAALPGPKAAREAF--EGKP..VIVISDAPAKKAK..EEFEQKGFGYILVNADSMIGARREFLDPTEMALFNADVVKVLAATGAFRIVQEEIDKVIEALKKGE...KPELPKVVITAERAVEAAKFSNPYAKAKAMAAYFIAEKVADVDVRGCFIEKDPEKYIPLVAAAHEMMRIAAKLADEAREIEKSNDTVFRNPHARD.G.KILSKTKLMEKP-q..
#=GC SS_cons                       E-EEEEEES--HHHHHTTGGGSTTS--SSEEEEEEEEET--SHHHHHHHHHHHHHHHHH..-SEEEEE-S-TTSHHHHHHHHHHHHSSS-EEE..EGGGGGGHHHHHH..-EEEEETTS------TTT--HHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTT---GGGS-E.EESGGGGGGSS--SSHHHHHHHHHHHHHHHHHHHHHHHHHHT---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT---B--B-TTSSB--BSS.T.---XXXXXXXXXX...
#=GC seq_cons                      .VKlGllKhGNIGoS.ll-LlLDERADRpsIpVRlhuSGsKMsPE-s-tlspp.h...c..pacPDFsIhlSPNuusPGPstAREhLtttslP..sIlIoDuPspKpc..-thcppGaGYIIlpsDsMIGARREFLDPsEMA.FNuDllKVLAsTGAhRllQpplDcVIctlcuGK...-l-LP+lVhss-KAV-tutFsNPYAKAKAhAAaphAppVAslsl+GCFMhK-hEcYlPlVAoAHEMMRsAApLA-EAREIEKusDoVhRpPHu+c.G.plLsKspLhpKP....
//
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