GenomeNet

Database: Pfam
Entry: Med2
LinkDB: Med2
Original site: Med2 
#=GF ID   Med2
#=GF AC   PF11214.7
#=GF DE   Mediator complex subunit 2
#=GF AU   Wood V, Coggill P
#=GF SE   Wood V
#=GF GA   21.70 21.70;
#=GF TC   21.70 21.80;
#=GF NC   21.60 21.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Mediator_(coactivator)
#=GF RN   [1]
#=GF RM   15175151
#=GF RT   A unified nomenclature for protein subunits of mediator
#=GF RT   complexes linking transcriptional regulators to RNA polymerase
#=GF RT   II. 
#=GF RA   Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ,
#=GF RA   Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M,
#=GF RA   Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP,
#=GF RA   Fukasawa T, Gustafsson CM, Han M, He X, Herman PK, Hinnebusch
#=GF RA   AG, Holmberg S, 
#=GF RL   Mol Cell. 2004;14:553-557.
#=GF RN   [2]
#=GF RM   14988503
#=GF RT   Site-specific Srb10-dependent phosphorylation of the yeast
#=GF RT   Mediator subunit Med2 regulates gene expression from the
#=GF RT   2-microm plasmid. 
#=GF RA   Hallberg M, Polozkov GV, Hu GZ, Beve J, Gustafsson CM, Ronne H,
#=GF RA   Bjorklund S; 
#=GF RL   Proc Natl Acad Sci U S A. 2004;101:3370-3375.
#=GF DR   INTERPRO; IPR021017;
#=GF CC   This family of mediator complex subunit 2 proteins is conserved
#=GF CC   in fungi. Cyclin-dependent kinase CDK8 or Srb10 interacts with
#=GF CC   and phosphorylates Med2. Post-translational modifications of
#=GF CC   Mediator subunits are important for regulation of gene
#=GF CC   expression [2].
#=GF SQ   70
#=GS A3GIB2_PICST/2-106       AC A3GIB2.2
#=GS W9Y4X5_9EURO/30-104      AC W9Y4X5.1
#=GS G0W4Z7_NAUDC/46-150      AC G0W4Z7.1
#=GS A0A0D2DUX2_9EURO/32-100  AC A0A0D2DUX2.1
#=GS K0KU99_WICCF/3-101       AC K0KU99.1
#=GS A0A0D2FI38_9EURO/30-101  AC A0A0D2FI38.1
#=GS J8Q3R0_SACAR/27-124      AC J8Q3R0.1
#=GS W2S8R1_9EURO/32-102      AC W2S8R1.1
#=GS A0A0N8H924_9HYPO/11-108  AC A0A0N8H924.1
#=GS W9VSH8_9EURO/26-100      AC W9VSH8.1
#=GS MED2_KLULA/10-161        AC Q6CJZ6.1
#=GS A0A0S8IX46_9BACT/1-60    AC A0A0S8IX46.1
#=GS H2AWU3_KAZAF/30-168      AC H2AWU3.1
#=GS Q59JS9_CANAL/78-181      AC Q59JS9.1
#=GS G8BEJ8_CANPC/4-106       AC G8BEJ8.1
#=GS M3K369_CANMX/4-107       AC M3K369.1
#=GS A0A132H506_9BACT/1-94    AC A0A132H506.1
#=GS A0A0D1YXL4_9EURO/32-100  AC A0A0D1YXL4.1
#=GS A0A0D2EWI6_9EURO/29-99   AC A0A0D2EWI6.1
#=GS S6E1X7_ZYGB2/19-119      AC S6E1X7.1
#=GS G8XZW6_PICSO/2-167       AC G8XZW6.1
#=GS G8Y2V7_PICSO/2-167       AC G8Y2V7.1
#=GS Q59L38_CANAL/4-106       AC Q59L38.1
#=GS C5DNG0_LACTC/36-139      AC C5DNG0.1
#=GS Q59KS8_CANAL/4-107       AC Q59KS8.1
#=GS E7NGM2_YEASO/27-126      AC E7NGM2.1
#=GS G3AIB7_SPAPN/5-109       AC G3AIB7.1
#=GS C5DPL2_ZYGRC/19-161      AC C5DPL2.1
#=GS H6BL10_EXODN/27-103      AC H6BL10.1
#=GS A0A0C7N1F3_9SACH/12-125  AC A0A0C7N1F3.1
#=GS Q5ACG3_CANAL/4-106       AC Q5ACG3.1
#=GS C5MIA5_CANTT/4-106       AC C5MIA5.1
#=GS Q5AAE6_CANAL/4-106       AC Q5AAE6.1
#=GS MED2_CANGA/2-160         AC Q6FWM4.1
#=GS I2H5C7_TETBL/22-121      AC I2H5C7.1
#=GS A0A0D1ZFG9_9EURO/30-100  AC A0A0D1ZFG9.1
#=GS A0A0A8LD02_9SACH/10-111  AC A0A0A8LD02.1
#=GS A0A072P0S2_9EURO/28-101  AC A0A072P0S2.1
#=GS Q5A121_CANAL/4-106       AC Q5A121.1
#=GS G8ZTP8_TORDC/21-149      AC G8ZTP8.1
#=GS Q59MI1_CANAL/4-111       AC Q59MI1.1
#=GS Q5AJW7_CANAL/4-113       AC Q5AJW7.1
#=GS C4Y5P3_CLAL4/2-104       AC C4Y5P3.1
#=GS Q5A0G8_CANAL/4-106       AC Q5A0G8.1
#=GS G8BNM5_TETPH/27-128      AC G8BNM5.1
#=GS A0A0D2FXJ8_9EURO/26-100  AC A0A0D2FXJ8.1
#=GS A0A0L0NYU4_9ASCO/2-105   AC A0A0L0NYU4.1
#=GS W9XMT2_9EURO/13-83       AC W9XMT2.1
#=GS A7TIL6_VANPO/13-117      AC A7TIL6.1
#=GS A0A0D2CTY0_9EURO/28-101  AC A0A0D2CTY0.1
#=GS Q5A7J9_CANAL/4-113       AC Q5A7J9.1
#=GS A5E6L9_LODEL/4-107       AC A5E6L9.1
#=GS J4TZU1_SACK1/27-124      AC J4TZU1.1
#=GS A0A0D2A8R3_9EURO/32-121  AC A0A0D2A8R3.1
#=GS Q59L80_CANAL/4-111       AC Q59L80.1
#=GS J7S3C1_KAZNA/2-106       AC J7S3C1.1
#=GS I6NDA8_ERECY/11-110      AC I6NDA8.1
#=GS Q5AB61_CANAL/4-106       AC Q5AB61.1
#=GS Q59JZ4_CANAL/4-119       AC Q59JZ4.1
#=GS W9WEP5_9EURO/27-100      AC W9WEP5.1
#=GS A0A0D2IR92_9EURO/32-123  AC A0A0D2IR92.1
#=GS A5DR23_PICGU/2-106       AC A5DR23.2
#=GS A0A0D2HQH0_9EURO/30-101  AC A0A0D2HQH0.1
#=GS MED2_YEAST/27-126        AC Q12124.1
#=GS Q6BXX9_DEBHA/2-106       AC Q6BXX9.2
#=GS MED2_ASHGO/20-119        AC Q757M0.1
#=GS G0V7X6_NAUCC/13-112      AC G0V7X6.1
#=GS Q59K56_CANAL/4-150       AC Q59K56.1
#=GS I2JYQ1_DEKBR/1-105       AC I2JYQ1.2
#=GS Q59L99_CANAL/4-106       AC Q59L99.1
A3GIB2_PICST/2-106                  .............NLQTKLDNSLNDILKTSGYIF--EIIN.NNRKQ..SNLITGTNNQLitpaiTSQLASNITRFDDILDETLSKLNDTRWCL.DQ.IMENKQKQEEMKLKE......ELERQKKlkEE--ee.............................................................
W9Y4X5_9EURO/30-104                 .......kdplny---------------------------.-----..-------AQST.....KAVLAETAKKFQDALDDCEIQILEAKWYL.EH.QLALNKARREAKAREd....sAAHAKRK..HEE-ikdeqek........................................................
G0W4Z7_NAUDC/46-150                 ............r-KTNKLTQCFDDILKLSTEMMVQQQLK.TIQLD..SNLINGFNENQ.....QNSLKEKINSFHGILDDLEISINKSLTYL.DT.ISKISIEKRKENIKTki..lkEQEEKEK..E---kqle...........................................................
A0A0D2DUX2_9EURO/32-100             ........pvnya---------------------------.-----..--------QST.....RAVLVETAKKFQDALDDCEVQILDAKWYL.EN.KLAQNRARREAKAKEd...saATAKRKR..D---eveg...........................................................
K0KU99_WICCF/3-101                  ..........nqi---DNLSLSFNEILLNVGTLF-DE-LV.SD-KT..TNLVLPNNNKK.....SNKLNDSIKQFDKNLDDILIQLNDISLFD.RK.LKQTKLEKEQAKLNN......NNTTDTQ..EK--qiep...........................................................
A0A0D2FI38_9EURO/30-101             ....kdplnyaps---------------------------.-----..----------T.....KAVLAETAKKFQDALDDCEVQILDAKWYL.ER.QLALNKARREAKAREds..aaSAKRKRD..E---tkea...........................................................
J8Q3R0_SACAR/27-124                 ............t-YKNKLTVCFDDILKVGAEMMMQQQLK.NVQLD..SYLVNGFSQPQ.....QRLLKEKVKLFHGILDDLETSLSQSSSYV.ET.LTVLGEERE--KERQ......EAERKKA..EEE-n..............................................................
W2S8R1_9EURO/32-102                 .....gnfgqstk---------------------------.-----..-----------.....-GIIQECSKQFQDALDDCEIQILDAKWYL.EH.QLRLRKQKRAEEAKA......REEQA--..----asakrkhdqvead..................................................
A0A0N8H924_9HYPO/11-108             .....dvlqlmvn-----------DVLVQTGKAL-----R.SSRKDgqGNVA-QAHGSL.....QSKLPDTIRTFHSALDDLEHDIIRAKSVLlRD.LTQIQEQKQQRHSQEqp..ppE------..----qiqhhqnqrq.....................................................
W9VSH8_9EURO/26-100                 ayvmkdpvnfapa---------------------------.-----..----------T.....KAVLAETAKKFHDALDDCEIQILNAKWYL.ER.QLAANRARREAKARDd...saS-SAKRK..R---devqd..........................................................
MED2_KLULA/10-161                   ............r-QENKLTQYFDDILRLSADLLTQQQLK.TIKLD..PKVTTGFSKAQ.....QKGLGDRITQFYSLLDTLDVSLQTTADYV.GA.VKDSALQLKKQREEE......QIKKQEQ..EK--lerqlleqqkleqqqleqkqlkqkqqqqqqqqqqqqqqqpqeqqheqqqrysak.........
A0A0S8IX46_9BACT/1-60               ...........mi------NKILNDVVNTASEFVGKALGY.NNEQR..RDIIT---NET.....KHALKAGINAFKSILDDMERDL-------.--.---------------......-------..----di.............................................................
H2AWU3_KAZAF/30-168                 ............y-ERNRLTSCLDDILKLSSEMIVQEQLK.TIQLS..NSIVSGFNINQ.....QRQLKDKIHTFHSILDDIDITLANTSNYI.VQ.LTEIGTERQIQIKQE......EEVLRRK..KQ--lqqeeelrrkkqleeeelkkkkqleaddelkrkkiqeqede......................
Q59JS9_CANAL/78-181                 .............NLQTRLHNSLDEILKSSGYIF--EVID.QNRKQ..SNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL.GV.MVEKKKKHDELKVKE......EAARKKR..EEE-ak.............................................................
G8BEJ8_CANPC/4-106                  .............NLQTKLENSLYEVLKTAGFIF--EVIN.NNKKQ..SALITGPNNQLiqptiIKQLTNHINEFDSILDETIFKFNDAKWCI.DT.MIENKQRQEEMKIKE......ELERQKR..EAE-a..............................................................
M3K369_CANMX/4-107                  .............NLQTKLDDTLNEILKTSGYIF--EIVN.NNKRQ..SNLITGPNNQPippyvIQKLNGQISKFDEILDETVSKFNDAKWCV.AT.MVENKQKQEELKARE......ELERQRR..EAE-ak.............................................................
A0A132H506_9BACT/1-94               ...........md---DNLNNGLDDLLNMFKKLM-----E.NQDLD..A--IPGINEEQ.....KEQLKMFLEDFDEMKDEMKVEIYKLDPFT.KQ.MIEMV----------......-------..----mgqlknfsgegmpatqqettpqe........................................
A0A0D1YXL4_9EURO/32-100             ......kdplnya---------------------------.-----..--------QST.....RAVLVETAKKFQDALDDCEIQILDAKWYL.EQkLAMNKARREKAREDI......AASAKRK..R---dved...........................................................
A0A0D2EWI6_9EURO/29-99              .....mkdplnya---------------------------.-----..--------HST.....RAVLVETAKKFQDALDDCEIQILDAKWYL.EH.KLAQNRARREAKAREd...saASAKRKR..D---eve............................................................
S6E1X7_ZYGB2/19-119                 ............v-HKNKLTQCFDDIMRVAAEMMLHQQLK.TVQLD..CSVVNGFSYNQ.....QRVLGEKIHVFHAILDDMETTLDKSKSYV.EA.VYETGREKEIKKERE......REELRRR..QEEEe..............................................................
G8XZW6_PICSO/2-167                  .............NLEEKLNDTLNEILKTSGYVF--EIIS.SNKRQ..SNIITGTNNQLispaiISQLSNSIARFDDILDDTTSKFNDAKWCI.ES.ILETRQK-EELKIRM......EEEKQKKirEQE-ekrrqdeelarkrreqeeernrierekdekmkeeamkrekeleekrkaeqereserqreqkaa
G8Y2V7_PICSO/2-167                  .............NLEEKLNDTLNDILKTSGYVF--EIIN.SNKRQ..SNIITGTNNQLispaiISQLSNSIARFDDILDDTTSKFNDAKWCI.ES.ILETRQK-EELKIRM......EEEKQKKirEQE-ekkrqdeelarkrreqeeernrierekdekmkeeamkrekeleqkrkaeqerelerqreqkaa
Q59L38_CANAL/4-106                  .............NLQTRLHNSLDEILKSSGYIF--EIID.QNRKQ..SNVITSPNNELiqksiTQSPNGEIQNFHAILDQTVSKLNDAEWRL.GV.MVEKKKKLDELKVKE......EAARKKE..EEA-k..............................................................
C5DNG0_LACTC/36-139                 ............v-HQSRLTQCFDEIMKTAAEMLVQQQIK.SIQLS..SDIAPGYTQKQ.....YKSLGDKVHAFHSVLDDLDLTLSASKSCV.DK.LALEAQERKQEAEKQri..keEEEARKK..----lsev...........................................................
Q59KS8_CANAL/4-107                  .............NLQTRLHNSLDEILKSSGYIF--EVID.QNRKQ..SNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL.GV.MVEKKKKLDELKVKE......EAARKKR..EEE-ak.............................................................
E7NGM2_YEASO/27-126                 ............t-YKNKLTVCFDDILKVGAEMMMQQQLK.NVQLD..SYLVNGFSQSQ.....QKLLKEKVKLFHGILDDLETSLSQSSSYL.ET.LTALGKEKE--KERE......EAEKKRA..EQE-nmr............................................................
G3AIB7_SPAPN/5-109                  .............NLQTKLDASLNDILKTSGYIF--EVLN.NNKKQ..SNLLTGPNNQLitpqiIAQLSHQMLKFDDILDETITKFNDARWCI.DQ.MVENKQRQEEMKIRE......EQERARRlkEE--ee.............................................................
C5DPL2_ZYGRC/19-161                 ............l-HENKLTQCFDDIMRVAVEMMLHQQLK.TVQLD..SSVVNGFSHNQ.....QRMLSEKIHIFHAILDDMETTLGKSKDYV.EA.IYELGREKELQKERE......REELRRR..QEEEerkskeqeelrrhqemelkaqqekeqqqqeqqeqqkqqkqdnd....................
H6BL10_EXODN/27-103                 ...ayaikdpany---------------------------.-----..-------AQST.....KAVLAETAKKFQDALDDCEIQILEAKWYL.EH.QLAVNKARREEKARQes..aaAHAKRKR..E---etted..........................................................
A0A0C7N1F3_9SACH/12-125             ............r-HQNKLTKCFDDIMKTAAEMLVQQQMK.SIQLS..SDIAAGFTQSQ.....HKLLGEKVHTFHSILDDLDLTLTTAKNCV.DK.FAAEAAARREKLLEEqrvqqiEQEKLKR..EQE-dqkrlieaq......................................................
Q5ACG3_CANAL/4-106                  .............NLQTRLHNSLDEILKSSGYIF--EIID.QNRKQ..SNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL.GV.MVEKKKKFEELKVIE......AAARKKR..EEE-a..............................................................
C5MIA5_CANTT/4-106                  .............NLQTRLDASLNEILKTSGYIF--EIIN.NNKKQ..SNLITGPNNQLiqpfvIQQLNNQIGKFDEILDETVSKFNDAKWCV.AT.MVENKQKQEELKLKE......EMERQKR..EAE-a..............................................................
Q5AAE6_CANAL/4-106                  .............NLQTRLHNSLDEILKSSGYIF--EIID.QNRKQ..SNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL.GV.MVEKKKKFDELKVKE......EEARKKR..EEE-a..............................................................
MED2_CANGA/2-160                    ............s-YKNRLTACFDDILKVSAEMMMQQQLK.NVQLD..PYMVNGFSAQQ.....QNTLKEKIHMFHGILDDLENMLSKSTYYV.DT.LANLGKESKRQKELE......LEKQREQ..EEE-ekkqkllelerkkkeqeeeeekkkkqkeeeekrkkeleeqerkkkeqeeeekrrrqqeqd...
I2H5C7_TETBL/22-121                 ............v-YKNQLTDCFDDILRLSAEMMVKQQMK.SIQLD..ASIVNGFNKNQ.....QNILNEKINLFHTILDDLALTIDNSKSYI.NE.IYQIGKEKKIQKEKE......EELRRIQ..EQEE...............................................................
A0A0D1ZFG9_9EURO/30-100             .......kdplny---------------------------.-----..-------AQST.....KAILAETAKKFQDALDDCEVQILDAKWHL.ER.QLALNKARREAKAKEe...saA-NAKRK..R---deskd..........................................................
A0A0A8LD02_9SACH/10-111             ............r-QENRLTQCFDDILRLSADLLTQQQLK.TIKLD..PKVTTGYSKSQ.....QKGLADRLSQFYSLIDTLDVSLQTTADYV.DA.VKDNASQLKKQREEE......QIKKQEQ..EK--lekq...........................................................
A0A072P0S2_9EURO/28-101             .....vlkdplny---------------------------.-----..-------AQST.....KAVLAETAKKFQDALDDCEIQILDVKWYL.ER.QLTLNKERREAKARE......DSA----..----aavsakrklddik..................................................
Q5A121_CANAL/4-106                  .............NLQTRLHNSLDEILKSSGYIF--EVID.QNRKQ..SNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL.GV.MVEKKKKHDELKVKE......EAVRKKR..EEE-a..............................................................
G8ZTP8_TORDC/21-149                 ............a-HRNRLTECFDDIMKVAAEMMVQQQLK.TVQLD..SAVVNGFSQAQ.....QRVLSEKIHMFHAILDDLQTTLTKSKSYV.GT.IHEIALEKQKVKEKE......RADLRKR..QEEEeqrknkeqeekarreemekkadgqrqqqs..................................
Q59MI1_CANAL/4-111                  .............NLQTRLHNSLDEILKSSGYIF--EIID.QNRKQ..SNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL.GV.MVEKKKKLDELKVKE......EAARKKE..E---gakkkaee.......................................................
Q5AJW7_CANAL/4-113                  .............NLQTRLHNSLDEILKSSGYIL--EVID.QNRKQ..SNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL.GV.MVEKKKKHDELKVKE......EAARKKC..EEE-akkkaeea.......................................................
C4Y5P3_CLAL4/2-104                  .............NLEAKLTSTLNDVLRSSGYIF--EIIN.NNKKQ..SNIVTGPNNQLipsqvTNQLAQSIAQFDQILDDTVSKFNDARWCI.EQ.MVDSRQKQEEMKHQE......EIERQRR..EEA-d..............................................................
Q5A0G8_CANAL/4-106                  .............NLQTRLHNSLDEILKSSGYIF--EVID.QNRKQ..SNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL.GV.MVEKKKKLDELKVKE......EAARKKE..E---gak............................................................
G8BNM5_TETPH/27-128                 ............k-YRNKVTQCFDDILDVSTQMLVQQQLK.TIQLD..INVTNGFNLSQ.....QKILHEKVNLFHSLLDDLECTLETSKTFT.EH.IAKLGKQREEEKLKK......DKEREEE..----lertrk.........................................................
A0A0D2FXJ8_9EURO/26-100             ayvmkdpvnfapa---------------------------.-----..----------T.....KAVLAETAKKFQDALDDCEIQILNAKWYL.ER.QLAANKARREAKARDl...saSTAKRKR..D---evqd...........................................................
A0A0L0NYU4_9ASCO/2-105              .............NLETRLTGTLNDVLRTSGYIF--EIIN.NNKRQ..SNLITGPNNQLipppiTAQLAASVAQFDLILDDTVSKFNDARWCV.EQ.IVENKQKQEELRIQE......EIERKKR..LEE-qr.............................................................
W9XMT2_9EURO/13-83                  ......ikdplny---------------------------.-----..-------AQST.....KAVLAETAKKFQDALDDCEIQILEAKWYL.EH.QLALNKARREAEAREe....sAAHAKRK..HE--eik............................................................
A7TIL6_VANPO/13-117                 ...........gg--KNKLVECFEDILEVSSQMLVQQQLK.SIQLD..NSVISGFNQGQ.....QKVLLEKVTLFHSILDDLEITLNKGKNYV.DE.LTKIGKDKEEERERVr...raEEEKKRL.lEEE-ek.............................................................
A0A0D2CTY0_9EURO/28-101             .....avkdplny---------------------------.-----..-------AQST.....KAVLAETAKKFQDALDDCEVQILEAKWYL.ER.QLALNKTRRETKAREds..aaSAKRKRD..E---skea...........................................................
Q5A7J9_CANAL/4-113                  .............NLQTRLHNSLDEILKSSGYIF--EVID.QNRKQ..SNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL.GV.MVEKKKKLDELKVKE......EEAKKKE..EEA-kkkeeeak.......................................................
A5E6L9_LODEL/4-107                  .............NLQTKLDSAFNDILRTAGFIF--EIIN.NNEKQ..NRLITGPNNQLiqptiIQQLTNHINKFDDILDETVFKFNDAKWCI.DT.MIENKQKQQEMKIKE......ELERQRR..EAEEa..............................................................
J4TZU1_SACK1/27-124                 ............t-YKNKLTVCFDDILKVGAEMMMQQQSK.NVQLD..SYLVNGFSHSQ.....QRLLKEKVKLFHGILDDLETSLNQSSSYV.NT.LTMLGKEK--EKERE......EAERRRA..EEE-n..............................................................
A0A0D2A8R3_9EURO/32-121             ........pvnya---------------------------.-----..--------QST.....RAVLVETAKKFQDALDDCEVQILDAKWYL.EN.KLAQNRARREAKAKEd...saATAKRKR..D---evegaqektqeaeqetaskrvktae......................................
Q59L80_CANAL/4-111                  .............NLQTRLHNSLDEILKSSGYIF--EIID.QNRKQ..SNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLDDAEWCL.GV.MVEKKKKLDELKVKE......EAARKKE..EEA-kkkeee.........................................................
J7S3C1_KAZNA/2-106                  ............t-EQNKLTRCFDDILRLSSEMLVQQQLK.TIQLD..T--VNGFTQDH.....QKVLSEKIHSFHGILDEVDVTLLNAVRFV.EK.FDAVSKEKELERVKQ.....rEREAQIT..AEEEarkkre.........................................................
I6NDA8_ERECY/11-110                 ............m-NTDRLTQCLDDIMRAATEMMVQQQLK.TIQLN..SDVAAGFRKNF.....SKSLGDKVRLFHSILDGVDTTLTTASQYL.ET.VDDVAHRMKQWKLRQ......EEELRRK..QQEE...............................................................
Q5AB61_CANAL/4-106                  .............NLQTRLHNSLDEILKSSGYIF--EIID.QNRKQ..SNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL.GV.MVEKKKKLDELKVKE......EEARKKR..EEE-a..............................................................
Q59JZ4_CANAL/4-119                  .............NLQTRLHNSLDEILKSSGYIF--EVID.QNRKQ..SNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL.GV.MVEKKKKLDELKVKE......EAAKKKE..EEA-kkaeqakkaeeakk.................................................
W9WEP5_9EURO/27-100                 ....yamkdplny---------------------------.-----..-------AQST.....KAVLAETAKKFQDALDDCEVQILDAKWYL.ER.QLALNKARREAKAREd...saASAKRKR..EE--pkd............................................................
A0A0D2IR92_9EURO/32-123             ........plnya---------------------------.-----..--------QST.....KAILVETAKKFQDALDDCEFQILDAKWYL.EH.QLALNKARREAKAREd...naASAKRKR..E---eikdaqekakeserenaskrvktvese....................................
A5DR23_PICGU/2-106                  .............NLEEKLRSSLDDVLCTSGYIF--EIIG.NNRKQ..SNLLTGTNNSLitpavTNSLARSLAKFDEVLDDTISKFNDTRWCV.EQ.IVENKQRQKEQKARE......EEERKRL..DDE-krk............................................................
A0A0D2HQH0_9EURO/30-101             .......kdplny---------------------------.-----..-------AQST.....KAVLAETAKKFQDALDDCEVQILDAKWYL.ER.QLALNKARREAKAREd...saASAKRKR..EE--skea...........................................................
MED2_YEAST/27-126                   ............t-YKNKLTVCFDDILKVGAEMMMQQQLK.NVQLD..SYLVNGFSQSQ.....QKLLKEKVKLFHGILDDLETSLSQSSSYL.ET.LTALGKEKE--KERE......EAEKKRA..EQE-nmr............................................................
Q6BXX9_DEBHA/2-106                  .............NLEEKLNNSLNDILKSSGYIF--EIIH.SRKKQ..SNLITGTNNQLitpviTSQLTNSITKFEDILDDTICKFNDTKWCV.EQ.MLQNRQKQEELKLKE......EEEKQRR..IKE-dde............................................................
MED2_ASHGO/20-119                   ...........mr--GDRLTQCLDDIMRASTEMMVQQQLK.TIQLN..SDVAAGFRKAL.....SKSLGDRVRAFHSILDGVETTLTTASQYL.DA.VEEAAVKMKQWKQQQ......EEEQRRK..HQAE...............................................................
G0V7X6_NAUCC/13-112                 ...........qp--KNKLTQCFDDILKISSEMLLQQQLK.TIQLD..SKVSNGFNASQ.....QRSLKEKINLFHGILDDLEISIAKSFDYV.DT.IVEISNEKLIKK---......-KELQRK..EEE-aaaaa..........................................................
Q59K56_CANAL/4-150                  .............NLQTRLHNSLDEILKSSGYIF--EIID.QNRKQ..SNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL.GV.MVEKKKKHDELKVKE......EAARKKR..EEE-akkkaeeakkaeeikkaeeakkveeakkaeeakkaeeakkaeeak..................
I2JYQ1_DEKBR/1-105                  ...........mt---NLLKDSMDNIFISSADILDKLTYKlSSATT..STVIPHNNDSLlk.plTDVLKXDFEAYNRVLDNYNLELLGAESML.TY.MKVKMKKEAELQQKM......ETERVKK..EKEEa..............................................................
Q59L99_CANAL/4-106                  .............NLQTRLHNSLDEILKSSGYIF--EIID.QNRKQ..SNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL.GV.MVEKKKKLDELKVKE......EAARKKR..EEE-a..............................................................
#=GC seq_cons                       ...............ps+Lppshs-IL+suu.hh..p.lp.p.php..usllsu.spph.....ppsLscplppFcsILDDspspls-AcWhl.-p.hlphp+cpcEhKh+E......-tt++++..Ep..t.t............................................................
//
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