GenomeNet

Database: Pfam
Entry: Med2
LinkDB: Med2
Original site: Med2 
#=GF ID   Med2
#=GF AC   PF11214.3
#=GF DE   Mediator complex subunit 2
#=GF AU   Wood V, Coggill P
#=GF SE   Wood V
#=GF GA   21.10 21.10;
#=GF TC   21.50 22.00;
#=GF NC   21.00 21.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   15175151
#=GF RT   A unified nomenclature for protein subunits of mediator
#=GF RT   complexes linking transcriptional regulators to RNA polymerase
#=GF RT   II. 
#=GF RA   Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ,
#=GF RA   Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M,
#=GF RA   Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP,
#=GF RA   Fukasawa T, Gustafsson CM, Han M, He X, Herman PK, Hinnebusch
#=GF RA   AG, Holmberg S, 
#=GF RL   Mol Cell. 2004;14:553-557.
#=GF RN   [2]
#=GF RM   14988503
#=GF RT   Site-specific Srb10-dependent phosphorylation of the yeast
#=GF RT   Mediator subunit Med2 regulates gene expression from the
#=GF RT   2-microm plasmid. 
#=GF RA   Hallberg M, Polozkov GV, Hu GZ, Beve J, Gustafsson CM, Ronne H,
#=GF RA   Bjorklund S; 
#=GF RL   Proc Natl Acad Sci U S A. 2004;101:3370-3375.
#=GF DR   INTERPRO; IPR021017;
#=GF CC   This family of mediator complex subunit 2 proteins is conserved
#=GF CC   in fungi. Cyclin-dependent kinase CDK8 or Srb10 interacts with
#=GF CC   and phosphorylates Med2. Post-translational modifications of
#=GF CC   Mediator subunits are important for regulation of gene
#=GF CC   expression [2].
#=GF SQ   58
#=GS A5DR23_PICGU/1-106    AC A5DR23.2
#=GS Q5AJW7_CANAL/1-109    AC Q5AJW7.1
#=GS MED2_KLULA/7-118      AC Q6CJZ6.1
#=GS C5DPL2_ZYGRC/17-128   AC C5DPL2.1
#=GS Q59L80_CANAL/1-121    AC Q59L80.1
#=GS G3AIB7_SPAPN/1-127    AC G3AIB7.1
#=GS C4YI74_CANAW/1-115    AC C4YI74.1
#=GS A6ZXW1_YEAS7/24-157   AC A6ZXW1.1
#=GS C7GXZ5_YEAS2/24-157   AC C7GXZ5.1
#=GS Q5A7J9_CANAL/1-114    AC Q5A7J9.1
#=GS G0W4Z7_NAUDC/43-151   AC G0W4Z7.1
#=GS C4YGC9_CANAW/1-108    AC C4YGC9.1
#=GS Q5AB61_CANAL/1-115    AC Q5AB61.1
#=GS Q6BXX9_DEBHA/1-171    AC Q6BXX9.2
#=GS Q5A121_CANAL/1-109    AC Q5A121.1
#=GS G8BEJ8_CANPC/1-109    AC G8BEJ8.1
#=GS Q5A0G8_CANAL/1-121    AC Q5A0G8.1
#=GS B3LGR3_YEAS1/24-157   AC B3LGR3.1
#=GS C8Z4R5_YEAS8/24-157   AC C8Z4R5.1
#=GS F0XWP0_AURAN/105-230  AC F0XWP0.1
#=GS Q59MI1_CANAL/1-114    AC Q59MI1.1
#=GS G0V7X6_NAUCC/10-123   AC G0V7X6.1
#=GS G8ZTP8_TORDC/20-149   AC G8ZTP8.1
#=GS H6BL10_EXODN/27-108   AC H6BL10.1
#=GS Q59L99_CANAL/1-108    AC Q59L99.1
#=GS A3GIB2_PICST/1-116    AC A3GIB2.2
#=GS MED2_CANGA/1-163      AC Q6FWM4.1
#=GS Q59K56_CANAL/1-150    AC Q59K56.1
#=GS B9WN82_CANDC/1-109    AC B9WN82.1
#=GS C4YFF1_CANAW/1-114    AC C4YFF1.1
#=GS G8XZW6_PICSO/1-112    AC G8XZW6.1
#=GS H0GDW7_9SACH/1-112    AC H0GDW7.1
#=GS G1UAF1_CANAX/1-121    AC G1UAF1.1
#=GS Q59JZ4_CANAL/1-119    AC Q59JZ4.1
#=GS C4YT65_CANAW/1-121    AC C4YT65.1
#=GS G8Y2V7_PICSO/1-166    AC G8Y2V7.1
#=GS C5MIA5_CANTT/1-108    AC C5MIA5.1
#=GS G8BNM5_TETPH/15-136   AC G8BNM5.1
#=GS B9WKI2_CANDC/1-197    AC B9WKI2.1
#=GS Q59KS8_CANAL/1-108    AC Q59KS8.1
#=GS C4YNA4_CANAW/1-114    AC C4YNA4.1
#=GS A5E6L9_LODEL/1-108    AC A5E6L9.1
#=GS MED2_YEAST/24-157     AC Q12124.1
#=GS E7NGM2_YEASO/24-157   AC E7NGM2.1
#=GS G2WCE9_YEASK/24-158   AC G2WCE9.1
#=GS C5DNG0_LACTC/31-144   AC C5DNG0.1
#=GS Q5ACG3_CANAL/1-154    AC Q5ACG3.1
#=GS H8X5X3_9ASCO/1-108    AC H8X5X3.1
#=GS O93946_CANAX/2-66     AC O93946.1
#=GS C4YNA8_CANAW/1-121    AC C4YNA8.1
#=GS Q59L38_CANAL/1-121    AC Q59L38.1
#=GS C4Y5P3_CLAL4/1-114    AC C4Y5P3.1
#=GS H2AWU3_KAZAF/28-169   AC H2AWU3.1
#=GS Q5AAE6_CANAL/1-108    AC Q5AAE6.1
#=GS A7TIL6_VANPO/11-181   AC A7TIL6.1
#=GS MED2_ASHGO/10-131     AC Q757M0.1
#=GS Q59JS9_CANAL/75-189   AC Q59JS9.1
#=GS C4YFX4_CANAW/1-119    AC C4YFX4.1
A5DR23_PICGU/1-106               ...........--MNLEEKLR...SSLDDVLCTSGYIF--EIIGNNRKQSNLLTGTNNSLitpavTNSLARSLAKFDEVLDDTISKFNDTRWCV....EQIVEN..KQRQK...........................EQK.AREEEE...RKRL........DDEKRK................................................................................
Q5AJW7_CANAL/1-109               ...........MPENLQTRLH...NSLDEILKSSGYIL--EVIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKHD...........................ELK.VKEEAA...RKKC........EEEAKKk...............................................................................
MED2_KLULA/7-118                 ........vsd---RQENKLT...QYFDDILRLSADLLTQQQLKTIKLDPKVTTGFSKAQ.....QKGLGDRITQFYSLLDTLDVSLQTTADYVgavkDSALQL..KKQRE...........................EEQiKKQEQE...KL--........------erqlleqqkl......................................................................
C5DPL2_ZYGRC/17-128              ........grl----HENKLT...QCFDDIMRVAVEMMLHQQLKTVQLDSSVVNGFSHNQ.....QRMLSEKIHIFHAILDDMETTLGKSKDYV....EAIYEL..GREKE...........................LQK.EREREE...LRRR.......qEEEERKskeqeel.........................................................................
Q59L80_CANAL/1-121               ...........MPENLQTRLH...NSLDEILKSSGYIF--EIIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLDDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEAA...RKKE........EEAKKKeeevkkkaeeakk...................................................................
G3AIB7_SPAPN/1-127               ........mss--ANLQTKLD...ASLNDILKTSGYIF--EVLNNNKKQSNLLTGPNNQLitpqiIAQLSHQMLKFDDILDETITKFNDARWCI....DQMVEN..KQRQE...........................EMK.IREEQE...RARRl......kEEEEQ-kqrrikeeqeeqaraka...............................................................
C4YI74_CANAW/1-115               ...........MPENLQTRLH...NSLDEILKSSGYIF--EIIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVKK..KKKHD...........................ELK.VKEEAA...RKKR........EAEAKKkaeeakk.........................................................................
A6ZXW1_YEAS7/24-157              .........rt--MTYKNKLT...VCFDDILKVGAEMMMQQQLKNVQLDSYLVNGFSQSQ.....QKLLKEKVKLFHGILDDLETSLSQSSSYL....ETLTAL..GKEK-...........................-EK.EREEAE...KKRA........EQEN--mrkvreqeelkkrqeleeasqqqqlqqnskekn...............................................
C7GXZ5_YEAS2/24-157              .........rt--MTYKNKLT...VCFDDILKVGAEMMMQQQLKNVQLDSYLVNGFSQSQ.....QKLLKEKVKLFHGILDDLETSLSQSSSYL....ETLTAL..GKEK-...........................-EK.EREEAE...KKRA........EQEN--mrkvreqeelkkrqeleeasqqqqlqqnskekn...............................................
Q5A7J9_CANAL/1-114               ...........MPENLQTRLH...NSLDEILKSSGYIF--EVIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEE-...AKKK........EEEAKKkeeeakk.........................................................................
G0W4Z7_NAUDC/43-151              .........le--NRKTNKLT...QCFDDILKLSTEMMVQQQLKTIQLDSNLINGFNENQ.....QNSLKEKINSFHGILDDLEISINKSLTYL....DTISKIsiEKRKEn.........................iKTK.ILKEQE...EKEK........EKQ---lel.............................................................................
C4YGC9_CANAW/1-108               ...........MPENLQTRLH...NSLDEILKSSGYIF--EIIGHNRKQSNVITSPNNELiqksiTQLLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKLD...........................ELK.IKEEAA...KKKE........EEAKK-a...............................................................................
Q5AB61_CANAL/1-115               ...........MPENLQTRLH...NSLDEILKSSGYIF--EIIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEEA...RKKR........EEEAKKkeeeakk.........................................................................
Q6BXX9_DEBHA/1-171               ...........--MNLEEKLN...NSLNDILKSSGYIF--EIIHSRKKQSNLITGTNNQLitpviTSQLTNSITKFEDILDDTICKFNDTKWCV....EQMLQN..RQKQE...........................ELK.LKEEEE...KQRRi......kEDDERKrleeektkkrkkeeeearikkekedqqakeeelkkkkeqeqkekeqkereslkenekksdann.................
Q5A121_CANAL/1-109               ...........MPENLQTRLH...NSLDEILKSSGYIF--EVIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKHD...........................ELK.VKEEAV...RKKR........EEEAKKa...............................................................................
G8BEJ8_CANPC/1-109               ...........MSANLQTKLE...NSLYEVLKTAGFIF--EVINNNKKQSALITGPNNQLiqptiIKQLTNHINEFDSILDETIFKFNDAKWCI....DTMIEN..KQRQE...........................EMK.IKEELE...RQKR........EAEAK-rl..............................................................................
Q5A0G8_CANAL/1-121               ...........MPENLQTRLH...NSLDEILKSSGYIF--EVIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEAA...RKKEega..kkkEEEA--kkkaeeakk.......................................................................
B3LGR3_YEAS1/24-157              .........rt--MTYKNKLT...VCFDDILKVGAEMMMQQQLKNVQLDSYLVNGFSQSQ.....QKLLKEKVKLFHGILDDLETSLSQSSSYL....ETLTAL..GKEK-...........................-EK.EREEAE...KKRA........EQEN--mrkvreqeelkkrqeleeasqqqqlqqnskekn...............................................
C8Z4R5_YEAS8/24-157              .........rt--MTYKNKLT...VCFDDILKVGAEMMMQQQLKNVQLDSYLVNGFSQSQ.....QKLLKEKVKLFHGILDDLETSLSQSSSYL....ETLTAL..GKEK-...........................-EK.EREEAE...KKRA........EQEN--mrkvreqeelkkrqeleeasqqqqlqqntkekn...............................................
F0XWP0_AURAN/105-230             ..miskqiril-----ENRLDkalQKFNESLAMNKQLR--EQIDNLRKERVVFDGIYKKL.....EKDLHEKKKEMAAIIEDSKVAYQRSDRAM....GEMVAL..KQQVD...........................KEK.AEFERE...W---........------rdlgklmeqdrqlreqlrrqsreeh.......................................................
Q59MI1_CANAL/1-114               ...........MPENLQTRLH...NSLDEILKSSGYIF--EIIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEAA...RKKE........EGAKKKaeeakk..........................................................................
G0V7X6_NAUCC/10-123              ........apt---QPKNKLT...QCFDDILKISSEMLLQQQLKTIQLDSKVSNGFNASQ.....QRSLKEKINLFHGILDDLEISIAKSFDYV....DTIVEI..SNE--...........................--K.LIKKKE...LQRK........EEEA--aaaaaaaaaeaqara.................................................................
G8ZTP8_TORDC/20-149              ........gah-----RNRLT...ECFDDIMKVAAEMMVQQQLKTVQLDSAVVNGFSQAQ.....QRVLSEKIHMFHAILDDLQTTLTKSKSYV....GTIHEI..ALEKQkvkek.................eradlR-K.RQEEEE...QRKN.......kEQEEK-arreemekkadgqrqqqs..............................................................
H6BL10_EXODN/27-108              ayaikdpanya----------...---------------------------------QST.....KAVLAETAKKFQDALDDCEIQILEAKWYL....EHQLAV..NKARR...........................EEK.ARQESAaahAKRK.......rE-----ettedeqskp......................................................................
Q59L99_CANAL/1-108               ...........MPENLQTRLH...NSLDEILKSSGYIF--EIIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEAA...RKKR........EEEAKK................................................................................
A3GIB2_PICST/1-116               ...........--MNLQTKLD...NSLNDILKTSGYIF--EIINNNRKQSNLITGTNNQLitpaiTSQLASNITRFDDILDETLSKLNDTRWCL....DQIMEN..KQKQE...........................EMK.LKEELE...RQKKl......kEEEERKrkeeerrk........................................................................
MED2_CANGA/1-163                 ..........m---SYKNRLT...ACFDDILKVSAEMMMQQQLKNVQLDPYMVNGFSAQQ.....QNTLKEKIHMFHGILDDLENMLSKSTYYV....DTLANL..GKESKrqkelelekqreqeeeekkqkllelerKKK.EQEEEE...EK--........------kkkqkeeeekrkkeleeqerkkkeqeeeekrrrqqeqdgdk.......................................
Q59K56_CANAL/1-150               ...........MPENLQTRLH...NSLDEILKSSGYIF--EIIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKHD...........................ELK.VKEEAA...RKKR........EEEAKKkaeeakkaeeikkaeeakkveeakkaeeakkaeeakkaeeak......................................
B9WN82_CANDC/1-109               ...........MSANLQIKLE...DALDDILKSAGFMF--EIINHNREQSNLIAGPNNELiqqsiVQQLNDNIQKFNDILDQTVSKFNDAKWCV....AVMIEN..KQKLE...........................ELK.IKEDGE...RQKR........DAEAK-rl..............................................................................
C4YFF1_CANAW/1-114               ...........MPENLQTRLH...NSLDEILKSSGYIF--EIIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLDDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEAA...RKKE........EEAKKKeeevkk..........................................................................
G8XZW6_PICSO/1-112               ...........--MNLEEKLN...DTLNEILKTSGYVF--EIISSNKRQSNIITGTNNQLispaiISQLSNSIARFDDILDDTTSKFNDAKWCI....ESILET..RQK-E...........................ELK.IRMEEE...KQKKi......rEQEEK-rrqdee..........................................................................
H0GDW7_9SACH/1-112               ...........----------...------------MMMQQQLKNVQLDSYLVNGFSQSQ.....QKLLKEKVKLFHGILDDLETSLSQSSSYL....ETLTAL..GKEK-...........................-EK.EREEAE...KKRA........EQEN--mrkvreqeelkkrqeleeasqqqqlqqnxkekn...............................................
G1UAF1_CANAX/1-121               ...........MPENLQTRLH...NSLDEILKSSGYIF--EVIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEAA...RKKEega..kkkEEEA--kkkaeeakk.......................................................................
Q59JZ4_CANAL/1-119               ...........MPENLQTRLH...NSLDEILKSSGYIF--EVIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEAA...KKKE........EEAKK-aeqakkaeeakk....................................................................
C4YT65_CANAW/1-121               ...........MPENLQTRLH...NSLDEILKSSGYIL--RVIDQNRKQSNVIRSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEAA...RKKEega..kkkEEEA--kkkaeeakk.......................................................................
G8Y2V7_PICSO/1-166               ...........--MNLEEKLN...DTLNDILKTSGYVF--EIINSNKRQSNIITGTNNQLispaiISQLSNSIARFDDILDDTTSKFNDAKWCI....ESILET..RQK-E...........................ELK.IRMEEE...KQKKi......rEQEEKKrqdeelarkrreqeeernrierekdekmkeeamkrekeleqkrkaeqerelerqreqka.....................
C5MIA5_CANTT/1-108               ...........MSANLQTRLD...ASLNEILKTSGYIF--EIINNNKKQSNLITGPNNQLiqpfvIQQLNNQIGKFDEILDETVSKFNDAKWCV....ATMVEN..KQKQE...........................ELK.LKEEME...RQKR........EAEAK-r...............................................................................
G8BNM5_TETPH/15-136              mlpptpndges--TKYRNKVT...QCFDDILDVSTQMLVQQQLKTIQLDINVTNGFNLSQ.....QKILHEKVNLFHSLLDDLECTLETSKTFT....EHIAKL..GKQRE...........................EEK.LKKDKE...REEElertrkrlE-----deeqk...........................................................................
B9WKI2_CANDC/1-197               ...........MSANLQTRLE...NSLNDILKASGYIF--EIINHNKKQSNLITGPNNELiqqsiIQQLSDHIQGFNDILDQTVSKFNDAKWCV....AVMIEN..KQKLEeeter.................qkreaEARrLKEEME...AKKK........AEEE--aaakaaaearakeeearaaarakeeearaaamakmeevaakakaameqekkekealrkkqeeeeeaqrkkleqqkrenqa
Q59KS8_CANAL/1-108               ...........MPENLQTRLH...NSLDEILKSSGYIF--EVIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEAA...RKKR........EEEAKK................................................................................
C4YNA4_CANAW/1-114               ...........MPENLQTRLH...NSLDEILKSSGYIF--EIIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEAA...RKKEega..kkkEEEA--kk..............................................................................
A5E6L9_LODEL/1-108               ...........MSANLQTKLD...SAFNDILRTAGFIF--EIINNNEKQNRLITGPNNQLiqptiIQQLTNHINKFDDILDETVFKFNDAKWCI....DTMIEN..KQKQQ...........................EMK.IKEELE...RQRR........EAEEA-k...............................................................................
MED2_YEAST/24-157                .........rt--MTYKNKLT...VCFDDILKVGAEMMMQQQLKNVQLDSYLVNGFSQSQ.....QKLLKEKVKLFHGILDDLETSLSQSSSYL....ETLTAL..GKEK-...........................-EK.EREEAE...KKRA........EQEN--mrkvreqeelkkrqeleeasqqqqlqqnskekn...............................................
E7NGM2_YEASO/24-157              .........rt--MTYKNKLT...VCFDDILKVGAEMMMQQQLKNVQLDSYLVNGFSQSQ.....QKLLKEKVKLFHGILDDLETSLSQSSSYL....ETLTAL..GKEK-...........................-EK.EREEAE...KKRA........EQEN--mrkvreqeelkkrqeleeasqqqqlqqnskekn...............................................
G2WCE9_YEASK/24-158              .........rt--MTYKNKLT...VCFDDILKVGAEMMMQQQLKNVQLDSYLVNGFSQSQ.....QKLLKEKVKLFHGILDDLETSLSQSSSYL....ETLTAL..GKEK-...........................-EK.EREEAE...KKRA........EQEN--mrkvreqeelkkrqeleeasqqqqlqqnskeknd..............................................
C5DNG0_LACTC/31-144              .....masesv----HQSRLT...QCFDEIMKTAAEMLVQQQIKSIQLSSDIAPGYTQKQ.....YKSLGDKVHAFHSVLDDLDLTLSASKSCV....DKLALE..AQERKq........................eaEKQrIKEEEE...ARKKl......sE-----vqkpet..........................................................................
Q5ACG3_CANAL/1-154               ...........MPENLQTRLH...NSLDEILKSSGYIF--EIIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKFEelkviea.............aarkkreEEA.KKKEEE...AKKK........EEE---akkkaeeakkkaeeakkkaeeakkaeeakkaeeav.............................................
H8X5X3_9ASCO/1-108               ...........MSANLQTKLE...NSLNEVLKTAGFIF--EVINSNKKQSTLIMGPNNQLiqpaiIKQLTNHINEFDSILDETIFKFNDAKWCI....DTMIEN..KQKQE...........................EMK.IKEELE...RQKR........EAEAK-r...............................................................................
O93946_CANAX/2-66                ..........i----------...--------------------------------QKSI.....TQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEEA...RKKR........EEEAKKk...............................................................................
C4YNA8_CANAW/1-121               ...........MPENLQTRLH...NSLDEILKSSGYIF--EIIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLDDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEAA...RKKE........EEAKKKeeevkkkaeeakk...................................................................
Q59L38_CANAL/1-121               ...........MPENLQTRLH...NSLDEILKSSGYIF--EIIDQNRKQSNVITSPNNELiqksiTQSPNGEIQNFHAILDQTVSKLNDAEWRL....GVMVEK..KKKLD...........................ELK.VKEEAA...RKKE........EEAKKKeeevkkkaeeakk...................................................................
C4Y5P3_CLAL4/1-114               ...........--MNLEAKLT...STLNDVLRSSGYIF--EIINNNKKQSNIVTGPNNQLipsqvTNQLAQSIAQFDQILDDTVSKFNDARWCI....EQMVDS..RQKQE...........................EMK.HQEEIE...RQRR........EEADRKrkeeeerk........................................................................
H2AWU3_KAZAF/28-169              ........lky----ERNRLT...SCLDDILKLSSEMIVQEQLKTIQLSNSIVSGFNINQ.....QRQLKDKIHTFHSILDDIDITLANTSNYI....VQLTEI..GTERQiqikqe...............eevlrrKKQ.LQQEEE...LRRKk.....qlEEEE--lkkkkqleaddelkrkkiqeqedel.......................................................
Q5AAE6_CANAL/1-108               ...........MPENLQTRLH...NSLDEILKSSGYIF--EIIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKFD...........................ELK.VKEEEA...RKKR........EEEAKK................................................................................
A7TIL6_VANPO/11-181              ........gtg----GKNKLV...ECFEDILEVSSQMLVQQQLKSIQLDNSVISGFNQGQ.....QKVLLEKVTLFHSILDDLEITLNKGKNYV....DELTKI..GKDKEeerer................vrraeeEKKrLLEEEE...KKRL.......lEEEEK-krlqlekekreeeelkkkkkleeeqeleleklkeqqqqqqaekdksneennsnnl.........................
MED2_ASHGO/10-131                ..matkfktde--EMRGDRLT...QCLDDIMRASTEMMVQQQLKTIQLNSDVAAGFRKAL.....SKSLGDRVRAFHSILDGVETTLTTASQYL....DAVEEA..AVKMK...........................QWK.QQQEEE...QRRKh.....qaE-----leknkrqqehda....................................................................
Q59JS9_CANAL/75-189              ...........MPENLQTRLH...NSLDEILKSSGYIF--EVIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKHD...........................ELK.VKEEAA...RKKR........EEEAKKkeeeakk.........................................................................
C4YFX4_CANAW/1-119               ...........MPENLQTRLH...NSLDEILKSSGYIF--EVIDQNRKQSNVITSPNNELiqksiTQSLNGEIQNFHAILDQTVSKLNDAEWCL....GVMVEK..KKKLD...........................ELK.VKEEAA...RKKE........EEAKK-aeqakkaeeakk....................................................................
#=GC seq_cons                    ..............NLps+Lp...ssLD-ILKoSGalh..ElIcpN++QSNlIousNNpLIp..lpppLsscIppFHuILDpTloKLNDAcWCL....sshlEp..KKKh-...........................EhK.lKEEtt...+K+c........EpEt..tcp.tct.........................................................................
//
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