GenomeNet

Database: Pfam
Entry: Merozoite_SPAM
LinkDB: Merozoite_SPAM
Original site: Merozoite_SPAM 
#=GF ID   Merozoite_SPAM
#=GF AC   PF07133.9
#=GF DE   Merozoite surface protein (SPAM)
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_15860 (release 10.0)
#=GF GA   27.50 27.50;
#=GF TC   28.00 28.00;
#=GF NC   26.70 25.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   7891748
#=GF RT   Molecular variation in a novel polymorphic antigen associated
#=GF RT   with Plasmodium falciparum merozoites. 
#=GF RA   McColl DJ, Silva A, Foley M, Kun JF, Favaloro JM, Thompson JK,
#=GF RA   Marshall VM, Coppel RL, Kemp DJ, Anders RF; 
#=GF RL   Mol Biochem Parasitol 1994;68:53-67.
#=GF RN   [2]
#=GF RM   7893643
#=GF RT   Solution structure of a polypeptide containing four heptad
#=GF RT   repeat units from a merozoite surface antigen of Plasmodium
#=GF RT   falciparum. 
#=GF RA   Mulhern TD, Howlett GJ, Reid GE, Simpson RJ, McColl DJ, Anders
#=GF RA   RF, Norton RS; 
#=GF RL   Biochemistry 1995;34:3479-3491.
#=GF DR   INTERPRO; IPR010784;
#=GF DR   SCOP; 1psm; fa;
#=GF CC   This family consists of several Plasmodium falciparum SPAM
#=GF CC   (secreted polymorphic antigen associated with merozoites)
#=GF CC   proteins. Variation among SPAM alleles is the result of
#=GF CC   deletions and amino acid substitutions in non-repetitive
#=GF CC   sequences within and flanking the alanine heptad-repeat domain.
#=GF CC   Heptad repeats in which the a and d position contain hydrophobic
#=GF CC   residues generate amphipathic alpha-helices which give rise to
#=GF CC   helical bundles or coiled-coil structures in proteins. SPAM is
#=GF CC   an example of a P. falciparum antigen in which a repetitive
#=GF CC   sequence has features characteristic of a well-defined
#=GF CC   structural element [1,2]. 
#=GF SQ   49
#=GS A0A024VQI0_PLAFA/1276-1434  AC A0A024VQI0.1
#=GS A5KAV5_PLAVS/740-898        AC A5KAV5.1
#=GS A0A024W6H3_PLAFA/237-404    AC A0A024W6H3.1
#=GS A0A024WR02_PLAFA/184-370    AC A0A024WR02.1
#=GS A0A024WQF5_PLAFA/195-353    AC A0A024WQF5.1
#=GS A0A024VYN0_PLAFA/303-335    AC A0A024VYN0.1
#=GS Q8IJ55_PLAF7/195-353        AC Q8IJ55.1
#=GS A0A024WP34_PLAFA/262-423    AC A0A024WP34.1
#=GS W7ALB0_9APIC/94-270         AC W7ALB0.1
#=GS B3LD32_PLAKH/777-919        AC B3LD32.1
#=GS A0A024WP38_PLAFA/237-404    AC A0A024WP38.1
#=GS A0A024VP97_PLAFA/240-427    AC A0A024VP97.1
#=GS K6UJ39_9APIC/370-521        AC K6UJ39.1
#=GS Q8IJ53_PLAF7/262-423        AC Q8IJ53.1
#=GS K6UUG1_9APIC/629-783        AC K6UUG1.1
#=GS Q8IJ54_PLAF7/184-370        AC Q8IJ54.1
#=GS K6UDR0_9APIC/490-643        AC K6UDR0.1
#=GS A5KAW0_PLAVS/692-851        AC A5KAW0.1
#=GS A5KAV8_PLAVS/1062-1242      AC A5KAV8.1
#=GS A0A024VPA1_PLAFA/570-765    AC A0A024VPA1.1
#=GS A0A024VP97_PLAFA/665-826    AC A0A024VP97.1
#=GS A0A024WPP7_PLAFA/530-699    AC A0A024WPP7.1
#=GS Q8IJ52_PLAF7/528-697        AC Q8IJ52.1
#=GS K6UKR2_9APIC/417-605        AC K6UKR2.1
#=GS A0A024VXL1_PLAFA/184-370    AC A0A024VXL1.1
#=GS A0A024VYN0_PLAFA/222-307    AC A0A024VYN0.1
#=GS Q7RQS5_PLAYO/117-315        AC Q7RQS5.1
#=GS K6UX80_9APIC/802-1000       AC K6UX80.1
#=GS Q8IJ45_PLAF7/571-762        AC Q8IJ45.1
#=GS A0A024VYU3_PLAFA/262-423    AC A0A024VYU3.1
#=GS A5KAV6_PLAVS/951-1139       AC A5KAV6.1
#=GS A5KDU7_PLAVS/513-670        AC A5KDU7.1
#=GS A0A024VQS1_PLAFA/528-691    AC A0A024VQS1.1
#=GS K6UX84_9APIC/730-894        AC K6UX84.1
#=GS B3L2C1_PLAKH/525-704        AC B3L2C1.1
#=GS A5KAV3_PLAVS/932-1110       AC A5KAV3.1
#=GS A0A024W7L4_PLAFA/528-697    AC A0A024W7L4.1
#=GS Q8IJ48_PLAF7/237-404        AC Q8IJ48.1
#=GS A0A024W5F7_PLAFA/576-771    AC A0A024W5F7.1
#=GS K6V8V9_9APIC/163-316        AC K6V8V9.1
#=GS A5KAV1_PLAVS/739-899        AC A5KAV1.1
#=GS A5KAV7_PLAVS/742-906        AC A5KAV7.1
#=GS A0A024WNY9_PLAFA/576-767    AC A0A024WNY9.1
#=GS K6UR85_9APIC/427-598        AC K6UR85.1
#=GS A0A024VQI6_PLAFA/289-456    AC A0A024VQI6.1
#=GS B3L6P2_PLAKH/816-960        AC B3L6P2.1
#=GS A5KAV4_PLAVS/939-1125       AC A5KAV4.1
#=GS Q4Y5Z4_PLACH/208-350        AC Q4Y5Z4.1
#=GS A5KAV2_PLAVS/863-1015       AC A5KAV2.1
A0A024VQI0_PLAFA/1276-1434             .................GWEFGGGVP..EHKKEEN...-----MLSHLYVSSKDKENISKENDDV--------...........LDEKEE.EAEETEE...E.........ELEE.KNEEET....--E....SEISE...DE...EEEEEEEE..KEEE..NDKKKEQEKE..Q.S.NEN.N---...........-----.-DQ.K......KDMEAQNLIS...................KNQNNNEKNvKEAAESIMKTLAGLIKGNNQ.IDSTLKDLVEELSKYFKN...
A5KAV5_PLAVS/740-898                   ............eflkt---------..-------...-KNQDILEPVEMFSGGTENVTDREEQV-KDEVEEQ...........GDGSNE.KAEEEEE...E.........DSES.ALPNGS....-DG....LEDDV...DL...---DVDDD..VEEE..E--NVATNHQ..K.G.GKY.----...........EKGKV.TDA.V......DDTNADKQFG...................DEFDAYNDI.KKVTEALVKTMTSLVSEDPS.VGDTINEFLSDMNQLF--ls.
A0A024W6H3_PLAFA/237-404               .................AWEIGGGAP..TYKPENN...KNDNILLEHVKITSWDKEDIIKENEDT--------...........----KR.EVQETED..tD.........ETED.TDETE-....--E....TEDME...DE...NEIVE-DQ..LQEN..EDDEDNVNLE..D.I.NKN.TRNDi.........fEEQIK.LDS.T......QDDKAQKLIS...................NEYKKTEE-.KKSLEDHVNLLFNFLQTNNQ.LDPSLKDLENELTFFLNN...
A0A024WR02_PLAFA/184-370               .................GWEFGGGAP..QNGAAED...KKTEYLLEQIKIPSWDRNNIPDENEQVKEDPQEDN...........KDEDED.EETETEN...L.........ETED.DNNEEI....EEN....EEDDI...DEesvEEKEEEEE..KKEE..EEKKEEKKEE..K.K.PDN.EITNe.........vKEEQK.YSS.P......SDINAQNLIS...................NKNKKNDET.KKTAENIVKTLVGLFNEKNE.IDSTINNLVQEMIHLFSN...
A0A024WQF5_PLAFA/195-353               .................GWEFGGGVP..EHKKEEN...-----MLSHLYVSSKDKENISKENDDV--------...........LDEKEE.EAEETEE...E.........ELEE.KNEEET....--E....SEISE...DE...EEEEEEEE..KEEE..NDKKKEQEKE..Q.S.NEN.N---...........-----.-DQ.K......KDMEAQNLIS...................KNQNNNEKNvKEAAESIMKTLAGLIKGNNQ.IDSTLKDLVEELSKYFKN...
A0A024VYN0_PLAFA/303-335               ...............en---------..-------...-----------------------------------...........------.-------...-.........----.------....---....-----...--...--------..----..----------..-.-.---.----...........-----.---.-......----------...................---------.-------MKTLAGLIKGNNQ.IDSTLKDLVEELSKYFKN...
Q8IJ55_PLAF7/195-353                   .................GWEFGGGVP..EHKKEEN...-----MLSHLYVSSKDKENISKENDDV--------...........LDEKEE.EAEETEE...E.........ELEE.KNEEET....--E....SEISE...DE...EEEEEEEE..KEEE..NDKKKEQEKE..Q.S.NEN.N---...........-----.-DQ.K......KDMEAQNLIS...................KNQNNNEKNvKEAAESIMKTLAGLIKGNNQ.IDSTLKDLVEELSKYFKN...
A0A024WP34_PLAFA/262-423               .................GIEFSGGLYfnEKKSTEE...NKQKNVLESVNLTSWDKEDIVKENEDV--------...........----KD.EKDEDD-...E.........EEEE.KYENEI....IKQ....PEDIL...DE...EEVLEEEI..LEEN..K---------..-.-.NDT.VDTSd.........lEKKNI.PDL.S......NDNNYYSLIY...................KNYKDNDKS.EKTAQTLITALISLLNGKNE.LDATIRRLKHRFMEFFTY...
W7ALB0_9APIC/94-270                    ......aqsaggptspa---------..------E...PEDHNSLREVESYEKDKCISSKEEEVLQERELEDD...........VEKEDA.HEGNTEK...G.........EGSD.STNDD-....DVN....LEDGD...EE...---VE-DE..NEDQ..EYSEQIAETQ..N.P.QKM.PMAQ...........-----.-NK.H......SDVGHESLITeaii..........hsvlaEKYNEIVKD.KKAAEAFVNTLLNLLDGDNSaIDDAIKHLAGDISQFV--fk.
B3LD32_PLAKH/777-919                   ...........agdmed---------..-------...------------------------K----ELEEEE...........EEEEEE.EDDEEEA..vE.........EEEE.VKEKEV....ANP....TETHD...GE..qEEAKE---..GEEN..GEHPSPSNTT..S.E.SQN.TNVQ...........SPEQV.VKP.L......SDSKAQALLT...................DTSKDLVDL.KKKVDQITKNIMNTLDGDTA.VLDTLKDFAKDLNQFI--lt.
A0A024WP38_PLAFA/237-404               .................AWEIGGGAP..TYKPENN...KNDNILLEHVKITSWDKEDIIKENEDT--------...........----KR.EVQETED..tD.........ETED.TDETE-....--E....TEDME...DE...NEIVE-DQ..LQEN..EDDEDNVNLE..D.I.NKN.TRNDi.........fEEQIK.LDS.T......QDDKAQKLIS...................NEYKKTEE-.KKSLEDHVNLLFNFLQTNNQ.LDPSLKDLENELTFFLNN...
A0A024VP97_PLAFA/240-427               .................GWEFGGGAP..QNGAAED...KKTEYLLEQIKIPSWDRNNIPDENEQVKEDPQEDN...........KDEDED.EETETEN...L.........ETED.DNNEEI....EEN....EEDDI...DEesvEEKEEEEE..KKEE..EEKKEEKKEE..K.K.PDN.EITNe.........vKEEQK.YSS.P......SDINAQNLIS...................NKNKKNDET.KKTAENIVKTLVGLFNEKNE.IDSTINNLVQEMIHLF--iqn
K6UJ39_9APIC/370-521                   .............nglk---------..-------...------------------NVEDEEETVLEETDEEE...........GDQMVD.ENEEEEE...G.........ETYEgEDTEDV....--A....LDEED...EE...GEKDE-EG..KAGE..EGNAGEG-GK..A.G.EEG.KAGE..........eGKAGE.QSV.E......EQNAEVPFIDt.................aTNNKGVRNI.KTETHNLVADLITILNADNG.IDQSLKALAKDMAQYFLN...
Q8IJ53_PLAF7/262-423                   .................GIEFSGGLYfnEKKSTEE...NKQKNVLESVNLTSWDKEDIVKENEDV--------...........----KD.EKDEDD-...E.........EEEE.KYENEI....IKQ....PEDIL...DE...EEVLEEEI..LEEN..K---------..-.-.NDT.VDTSd.........lEKKNI.PDL.S......NDNNYYSLIY...................KNYKDNDKS.EKTAQTLITALISLLNGKNE.LDATIRRLKHRFMEFFTY...
K6UUG1_9APIC/629-783                   .............almr---------..-------...TKKKYVLEPLEITSEEGNNITGKEEQV-KEEIEEQ...........EDKGND.EEEEDV-...E.........KTDQ.TVIDEV....DIN....VDNDE...EE...EGTAEEQG..EEEG..--EKDTTEKE..I.K.EEQ.ASGE...........-----.-KI.L......DDKEAHKTLA...................GNFKESSPA.KTEGAEFLKTLINDVG----.-EDTLKNLQQDLHQYFK-g..
Q8IJ54_PLAF7/184-370                   .................GWEFGGGAP..QNGAAED...KKTEYLLEQIKIPSWDRNNIPDENEQVIEDPQEDN...........KDEDED.EETETEN...L.........ETED.DNNEEI....EEN....EEDDI...DEesvEEKEEEEE..KKEE..EEKKEEKKEE..K.K.PDN.EITNe.........vKEEQK.YSS.P......SDINAQNLIS...................NKNKKNDET.KKTAENIVKTLVGLFNEKNE.IDSTINNLVQEMIHLFSN...
K6UDR0_9APIC/490-643                   ..............lkt---------..-------...-KNQHVLELLDISSESANNITSKEEQVMEEVEEPG..........nEDNDEA.EVEEAL-...P.........KDSD.GQEEDV....SLE....MDDGE...EV...---E---E..VEED..A--------A..S.N.QQN.GGNR...........EKRNV.IDT.M......DDTNAEKQFG...................NELNSYNDI.KKVTEALVKSMTSLVSEDPS.IGDTIKEFLSDMNHVF--ls.
A5KAW0_PLAVS/692-851                   .........kaaygllk---------..-------...TKNQYVLEPLDISPESADNITSKEEQV-KEEMEDQ...........GDEDSN.EAEVEEA..lP.........NGSG.AQEEDV....--N....LE-MD...DE...EEVEE---..VEEN..VATNQQTGG-..-.-.---.--KR...........EKRNT.NDT.V......DDTNADKQFG...................DEFDTYNDI.KKVTEALVKSMTSLVSDDPS.VGDTINEFLSDMNHLF--ls.
A5KAV8_PLAVS/1062-1242                 ...saekaqkaaaesal---------..-------...KKKLNVLEIVKKYSKESYNTVDSDEHVLNEVEEQA...........SEEKEE.EEEEEE-...A.........EHSV.SNEVEI....EDD....EEEEE...EE...EEEGEETN..TEGEksEDNSPHSDTE..P.Q.EQN.QSVK...........PPEQS.EKT.L......NDSNTQALLS...................DNYKNVANF.KKMADDLTKNIISTIDGDTG.VIDTLKDFAEDLNQFI--fs.
A0A024VPA1_PLAFA/570-765               .................ELSSGSSSL..EQHSKED...VKKGSALELVPLSLSDIEQIANESEDVLEEIEEEIntdgeieyitdEEIKED.IEEETEEdieE.........ETEE.ETEEET....EEE....TEEEA...DE...ETVKEIED..KPEQ..EIKNKSLEEK..Q.I.DKN.TDTS...........EKKGF.NNS.E......KDEKARNLIS...................KNYKNYNEL.DKNVHTLVNSIISLLEEGNG.SDSTLNSLSKDITNLFKN...
A0A024VP97_PLAFA/665-826               .................GIEFSGGLYfnEKKSTEE...NKQKNVLESVNLTSWDKEDIVKENEDV--------...........----KD.EKDEDD-...E.........EEEE.KYENEI....IKQ....PEDIL...DE...EEVLEEEI..LEEN..K---------..-.-.NDT.VDTSd.........lEKKNI.PDL.S......NDNNYYSLIY...................KNYKDNDKS.EKTAQTLITALISLLNGKNE.LDATIRRLKHRFMEFFTY...
A0A024WPP7_PLAFA/530-699               ...glgsgalpgtniit---------..-------...-EEKYSVELIKLTSKDEEDIIKHNEDVREEIEEQQ...........EDIEED.EEELENE..gE.........ETKE.EDDEE-....KNE....TNDTE...DT...DDTEDTED..IEEE..NKEKELSNQQ..Q.S.EKK.S---...........-----.-IS.K......VDEDSYRILS...................VSYKDNNEV.KNVAESIVKKLFSLFNDNNN.LETIFKGLTEDMTDLFQ-k..
Q8IJ52_PLAF7/528-697                   ...glgsgalpgtniit---------..-------...-EEKYSLELIKLTSKDEEDIIKHNEDVREEIEEQQ...........EDIEED.EEELENE..gE.........ETKE.EDDEE-....KNE....TNDTE...DT...DDTEDTED..IEEE..NKEKELSNQQ..Q.S.EKK.S---...........-----.-IS.K......VDEDSYRILS...................VSYKDNNEV.KNVAESIVKKLFSLFNDNNN.LETIFKGLTEDMTDLFQ-k..
K6UKR2_9APIC/417-605                   ........atkaaekaq---------..--KAAEEsaiRKKLKILEIVKKYSKEGFNGVDNDEQVLNEIEEQG...........NEDEEE.DEEEDEK..eE.........EIVK.DTLPE-....-KE....EELDE...DE...EEEEEEGI..EEEK..EDVEMETDED..K.SePDN.GEPAqnr.....smqPPEQA.DKP.L......SDSNAQVLLA...................GNSKNFMDT.KKKDDGVTKNIINIIDGDTE.VLDTLMDFAKDVDQFI--fn.
A0A024VXL1_PLAFA/184-370               .................GWEFGGGAP..QNGAAED...KKTEYLLEQIKIPSWDRNNIPDENEQVIEDPQEDN...........KDEDED.EETETEN...L.........ETED.DNNEEI....EEN....EEDDI...DEesvEEKEEEEE..KKEE..EEKKEEKKEE..K.K.PDN.EITNe.........vKEEQK.YSS.P......SDINAQNLIS...................NKNKKNDET.KKTAENIVKTLVGLFNEKNE.IDSTINNLVQEMIHLFSN...
A0A024VYN0_PLAFA/222-307               .................GWEFGGGVP..EHKKEEN...-----MLSHLYVSSKDKENISKENDDV--------...........LDEKEE.EAEETEE...E.........ELEE.KNEEET....--E....SEISE...DE...EEEEEEEE..KEEE..NMK-------..-.-.---.----...........-----.---.-......----------...................---------.--------------------.------------------t..
Q7RQS5_PLAYO/117-315                   .......avvpgspssd---------..---SEIE...-EPQNVLTEITIESTENVQITEEELAVCEEIE-ES...........YDEMEE.EEEETE-...E.........QIPE.NFEINIeedeDEE....EEEEE...EE...EEVEEEEQ..TSST..E--NPEAGEQ..G.S.TQT.QESNg.........tNPESS.TQT.N......TDENGQTIKKgttggaaplinaisndpinAESRNVVES.KQEAKEIMKTLVTMFDDVDV.FDEPVFDFSDDISQFL--i..
K6UX80_9APIC/802-1000                  ....eaaekakkaaees---------..-----AT...KKEHKILEIVKKYSKEGYNGVDNDEQVLNEIEEQG...........NEEKEE.EEEEDAD...Hivp...kdvEIGD.DNEEEE....EEEeeegEEEEE...EE...EEVKEDEE..VKEE..KETKEEGQAQ..S.S.AHK.---SsvaelenekkqSKEEN.DKP.P......SDNNAHTLLE...................DNYKNFMDF.KKKTEGMTKNIIKTIDGDTE.VLDTLKDFANDVDLFI--ln.
Q8IJ45_PLAF7/571-762                   .................ELSSGSSSL..EQHSKED...VKKGCALELVPLSLSDIEQIANESEDVLEEIEEEIntdgeieyiteEEIKED.IEEETE-...E.........DIEE.ETEEET....EEE....TEEEA...DE...ETVKEIED..KPEQ..EIKNKSLEEK..Q.I.DKN.TDTS...........EKKGF.NNS.E......KDEKARNLIS...................KNYKNYNEL.DKNVHTLVNSIISLLEEGNG.SDSTLNSLSKDITNLFKN...
A0A024VYU3_PLAFA/262-423               .................GIEFSGGLYfnEKKSTEE...NKQKNVLESVNLTSWDKEDIVKENEDV--------...........----KD.EKDEDD-...E.........EEEE.KYENEI....IKQ....PEDIL...DE...EEVLEEEI..LEEN..K---------..-.-.NDT.VDTSd.........lEKKNI.PDL.S......NDNNYYSLIY...................KNYKDNDKS.EKTAQTLITALISLLNGKNE.LDATIRRLKHRFMEFFTY...
A5KAV6_PLAVS/951-1139                  ...aaekakkaaeesal---------..-------...KKKLKVLEIVKKYSKEGYNTVDSDEHVLNEVEEQA...........SEAKEE.EEEDDE-...E.........EAEH.SLPNDV....EIE....DDDDE...GE...EEEKEEEEteVKEE..EDVKEEGHAQ..S.S.AHQsSVTE..........lENQKA.QSQ.EksekplSDSNAQALLE...................DNYKDVVNF.KKMADGLTKNIISTIDGDTD.VLDTLKDFAEDLNQFI--fs.
A5KDU7_PLAVS/513-670                   .............ppdp---------..-------...----NSLQEVNTSEKDKDVSSKEEEVLVEKGVEDD...........AQDGGH.DDDTGEG...G.........ETDS.ANQDDV....SLE....YDDEE...VE...----E--E..NEDA..EYSQQITETQ..N.G.KSN.SPTV...........---GL.ESL.I......SDATVHDALA...................EQCKDNVQG.KKEAEAFVNTLLDLLDGSNSaADNAIKNLADDISQFL--lk.
A0A024VQS1_PLAFA/528-691               ...glgsgalpgtniit---------..-------...-EEKYSLELIKLTSKDEEDIIKHNEDVREEIEEQQ...........EDIEED.EEELENE..gE.........ETKE.EDDEE-....KNE....TNDTE...DT...------ED..IEEE..NKEKELSNQQ..Q.-.---.---S...........EKK--.SIS.K......VDEDSYRILS...................VSYKDNNEV.KNVAESIVKKLFSLFNDNNN.LETIFKGLTEDMTDLFQ-k..
K6UX84_9APIC/730-894                   ............ylkli---------..-------...--KQDILEPLHISPEASDNVIDKNEQVTQEAEDRG...........SEENDDtIEDVTP-...S.........DVGE.EGEGEL....EDE....EEGEE...DE...EEEEEEEQ..KNEE..PPGQPQTQQD..DaI.SKE.NGTA...........ETQKG.EEV.L......DDQGAHKLLA...................GENNIANQI.KKAENALLKTMINEIE----.-DATIHNLLQDMSHFLK-g..
B3L2C1_PLAKH/525-704                   ..............vpp------STS..EHTSNEN...AAKLNILEEVNITEETKDINPKEEEELVEEEVQED...........LEKEEE.EESETEE..gG.........ETDS.ANYDDV....DVE....VDDDD...EE...----EQDE..IEDQ..EILQPITETQ..N.S.QEN.PTEQ...........-----.-NN.P......ADVGHKSLITeamv..........hsafaEEYKDNVKD.KKAAEAFVNTLLDLLDGDNStVDDAIKNLANDISQFM--lk.
A5KAV3_PLAVS/932-1110                  aaeaaekakkaaaesal---------..-------...KKKLKVLEIVKKYSKRGYNVVDNDEQVLNEVDEQA...........SEAKE-.E--EDE-...D.........EADD.SASSDV....--E....IEDDE...EE...EEEED-EE..VKEE..EGQAQSSAHQ..N.S.VAE.LENQk.........kESQEKsDEP.P......SDNNAQALLS...................DNYKNFTDF.KKKAEDLTKNIINTIDGDAG.VIDTLKDFANDVNQFIL-n..
A0A024W7L4_PLAFA/528-697               ...glgsgalpgtniit---------..-------...-EEKYSLELIKLTSKDEEDIIKHNEDVREEIEEQQ...........EDIEED.EEELENE..gE.........ETKE.EDDEE-....KNE....TNDTE...DT...DDTEDTED..IEEE..NEEKELSNQQ..Q.S.EKK.S---...........-----.-IS.K......VDEDSYRILS...................VSYKDNNEV.KNVAESIVKKLFSLFNDNNN.LETIFKGLTEDMTDLFQ-k..
Q8IJ48_PLAF7/237-404                   .................AWEIGGGAP..TYKPENN...KNDNILLEHVKITSWDKEDIIKENEDT--------...........----KR.EVQETED..tD.........ETED.TDETE-....--E....TEDME...DE...NEIVE-DQ..LQEN..EDDEDNVNLE..D.I.NKN.TRNDi.........fEEQIK.LDS.T......QDDKAQKLIS...................NEYKKTEE-.KKSLEDHVNLLFNFLQTNNQ.LDPSLKDLENELTFFLNN...
A0A024W5F7_PLAFA/576-771               .................ELSSGSSSL..EQHSKED...VKKGSTLELVPLSLSDIEQIANESEDVLEEIEEEIntdgeieyiteEEIKED.IEEETEEdieE.........ETEE.ETEEET....EEE....AEEEA...DE...ETVKEIED..KPEQ..EIKNKSLEEK..Q.I.DKN.TDTS...........EKKGF.NNS.E......KDEKARNLIS...................KNYKNYNEL.DKNVHTLVNSIISLLEEGNG.SDSTLNSLSKDITNLFKN...
K6V8V9_9APIC/163-316                   .......vtppreaesn---------..-------...-------------------------TLIDN-KKLK...........LERDQE.AQKSVNDv.qE.........EVQD.ENYDDG....DDN...rVDEDT...DE...GTGEGIDD..NTDE..DADEEIVYRY..D.S.EEE.AKIN..........mEEQGF.NSL.V......NDETIHMIHF...................QEYTDVEEG.KEKVEELVQYMTNSFKENEQ.LVDTLNDFSDDIIMYLQ-k..
A5KAV1_PLAVS/739-899                   ....siykteyeylkli---------..-------...--KQDVLEPLKVSTEASDNVFDKNEQV----AQEV...........EDRGSE.ENDA---...-.........AEED.AAPSDV....EED....EGELE...DE...EEEEEEVE..QLE-..--QPQEQQTD..A.S.SKD.KGTA...........ETQKS.EDV.L......DDEGAHKLLA...................GELNTANKS.NNAENALFKTVFDE-----V.RDDTIQNLKQDVGQFFK-g..
A5KAV7_PLAVS/742-906                   ........ikaaheflk---------..-------...TKNQDILEPVEMFSGGTENVTDREEQV-KEEVEEQ...........GDGNNE.QAEEAEE..vD.........ESES.ALPNG-....SDG....LEDDV...DF...----DVDD..GEEE..E-ENVATNKQ..K.G.GKY.----...........EKGKV.TDA.V......DDTNADKQFG...................DEFDAYNDI.KKVTEALVKTMTSLVSEDPS.VGDTINEFLSDMNQLF--ls.
A0A024WNY9_PLAFA/576-767               .................ELSSGSSSL..EQHSKED...VKKGCALELVPLSLSDIEQIANESEDVLEEIEEEIntdgeieyiteEEIKED.IEEETE-...E.........DIEE.ETEEET....EEE....TEEEA...DE...ETVKEIED..KPEQ..EIKNKSLEEK..Q.I.DKN.TDTS...........EKKGF.NNS.E......KDEKARNLIS...................KNYKNYNEL.DKNVHTLVNSIISLLEEGNG.SDSTLNSLSKDITNLFKN...
K6UR85_9APIC/427-598                   .........ggvnsgqt---------..-------...-ADPNSLQAVNLSDKDKDISSKEEEVLVEREVEND...........VEKENA.NEDDTED..eG.........ETDS.ANYDDV....DVE....EDDEE...VE...------DE..IEDP..EYAQQITETQ..N.A.QKM.PTAQ...........-----.-NN.P......PDVGHKSLISeaiv..........hsalaEEYKDTMKG.KKEAEAFVNTLLDLLDGDNSeVDDAIKNLADDISQFV--lk.
A0A024VQI6_PLAFA/289-456               .................AWEIGGGAP..TYKPENN...KNDNILLEHVKITSWDKEDIIKENEDT--------...........----KR.EVQETED..tD.........ETED.TDETE-....--E....TEDME...DE...NEIVE-DQ..LQEN..EDDEDNVNLE..D.I.NKN.TRNDi.........fEEQIK.LDS.T......QDDKAQKLIS...................NEYKKTEE-.KKSLEDHVNLLFNFLQTNNQ.LDPSLKDLENELTFFLNN...
B3L6P2_PLAKH/816-960                   ................a---------..-------...------------------------DDV-EDDVEDD...........NDDDED.EEEEEEN...D.........VVEE.EGQVKV....EEK....EEVDQstvQE...GELEKANQ..GEET..EENTPPSDTP..P.K.EQN.SNVQ...........SPEQV.VKP.L......SDSKAQALLT...................DNNKNFIDL.KKKVDQITKNIMNTLDGDTT.VLDTLKDFAEDLNQFI--lt.
A5KAV4_PLAVS/939-1125                  .......akkaaaesal---------..-------...KKKLNVLEIVKKYSREGYNTVDSDEHVLNEVEEQA...........SEEKEE.GEREEEE...EadhpilndvEIDD.DDEEEE....EEE....EEKEE...EE...TEVKEEED..AKEE..GHAQSSAHQS..S.I.TEL.ENPK..........kEYQEK.SDKpP......SDSNAQALLE...................DNYKNFTDF.KKKAEDLTKNIINTIDGDAG.VIETLKDFAKDMNQFIL-n..
Q4Y5Z4_PLACH/208-350                   .................---------..-------...----------------------------EEEEEED...........DDEDEN.VVDESVN..vI.........ESDA.EKQDDN....KEE....TESEE..dDE..nNDVAE-EA..LNEA..NETNENEKEKvpK.E.SEN.ETTE..........kEEDKE.EPT.T......IDSKAKKIIS...................EYYQNMKNI.KNKIKDYVKSAMDLIDGNNG.ISKAFSNLSEDISNFI--lk.
A5KAV2_PLAVS/863-1015                  .............alir---------..-------...TKKQYALEPLEITSEAGYNITEKEEQVKEEIEEQ-...........DDKASE.EEEEDT-...Q.........QIDQ.TQIDEV....DIS....VDNEE...EE...EGAAE-EQ..IEGE..KD-TPTKE--..-.A.KEE.Q-TS...........GEK--.--I.L......DDKEAHKTLA...................EKFKDSNTA.KTGGVEFLETLISDVGE---.--DTLKNLQQDLHQYFK-g..
#=GC seq_cons                          .......................................cpt.hLE.lplsSt-ppslsccsEpV.p-..Ept...........t-tc--.Ec-EsEp...-.........Es--.pspcEh....p.-....pE-p-...DE...--hcE.-p..hcEp..c.pppttppp..p.t.scs.s.sp...........pppt...ss........sDpsAppLlu...................ppaKsssch.KKss-sllcslhsllsssNp.l-sTl+sLspDhspah.....
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