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Database: Pfam
Entry: Microvir_lysis
LinkDB: Microvir_lysis
Original site: Microvir_lysis 
#=GF ID   Microvir_lysis
#=GF AC   PF04517.8
#=GF DE   Microvirus lysis protein (E), C terminus
#=GF AU   Kerrison ND
#=GF SE   DOMO:DM04358;
#=GF GA   25.00 25.00;
#=GF TC   25.90 25.20;
#=GF NC   22.00 17.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12100551
#=GF RT   The Escherichia coli FKBP-type PPIase SlyD is required for the
#=GF RT   stabilization of the E lysis protein of bacteriophage phiX174. 
#=GF RA   Bernhardt TG, Roof WD, Young R; 
#=GF RL   Mol Microbiol 2002;45:99-108.
#=GF DR   INTERPRO; IPR007605;
#=GF CC   E protein causes host cell lysis by inhibiting MraY, a
#=GF CC   peptidoglycan biosynthesis enzyme.  This leads to cell wall
#=GF CC   failure at septation [1]. The N terminal transmembrane region
#=GF CC   matches the signal peptide model and must be omitted from the
#=GF CC   family.
#=GF SQ   84
#=GS Q2LLI9_9VIRU/33-76      AC Q2LLI9.1
#=GS Q2LLR6_9VIRU/34-75      AC Q2LLR6.1
#=GS Q2LLY2_9VIRU/34-75      AC Q2LLY2.1
#=GS Q2LLL1_9VIRU/34-75      AC Q2LLL1.1
#=GS L7TNY5_9VIRU/34-75      AC L7TNY5.1
#=GS S5VLY4_9VIRU/34-75      AC S5VLY4.1
#=GS VGE_BPG4/34-75          AC P03640.1
#=GS Q2LLX1_9VIRU/34-75      AC Q2LLX1.1
#=GS Q8W6C5_BPG4/34-75       AC Q8W6C5.1
#=GS Q2LL79_9VIRU/34-75      AC Q2LL79.1
#=GS D0U1B1_BPG4/34-75       AC D0U1B1.1
#=GS S5VZD0_9VIRU/34-75      AC S5VZD0.1
#=GS Q2LLP4_9VIRU/34-75      AC Q2LLP4.1
#=GS Q2LM77_9VIRU/34-71      AC Q2LM77.1
#=GS C6K2G5_BPST1/34-73      AC C6K2G5.1
#=GS A3FJD7_BPPHX/34-75      AC A3FJD7.1
#=GS Q2LL46_9VIRU/34-75      AC Q2LL46.1
#=GS A0A025JF54_ECO57/1-41   AC A0A025JF54.1
#=GS Q2LM87_9VIRU/34-71      AC Q2LM87.1
#=GS D0U139_BPPHX/34-75      AC D0U139.1
#=GS Q2LLF6_9VIRU/34-74      AC Q2LLF6.1
#=GS A3FJU1_BPPHX/34-75      AC A3FJU1.1
#=GS F8RMM2_BPPHX/34-75      AC F8RMM2.1
#=GS Q2LM67_9VIRU/34-71      AC Q2LM67.1
#=GS A0A028SWC8_ECOLX/1-40   AC A0A028SWC8.1
#=GS Q2LLH8_9VIRU/33-76      AC Q2LLH8.1
#=GS VGE_BPS13/34-75         AC P07930.2
#=GS A3FJQ8_BPPHX/34-75      AC A3FJQ8.1
#=GS Q9G088_BPS13/34-75      AC Q9G088.1
#=GS E_BPPHS/34-75           AC P03639.2
#=GS X5WR77_9RHIZ/1-26       AC X5WR77.1
#=GS Q2LLC3_9VIRU/34-70      AC Q2LLC3.1
#=GS Q5C8R8_9VIRU/34-74      AC Q5C8R8.1
#=GS F8RLU7_BPPHX/34-75      AC F8RLU7.1
#=GS Q2LM36_9VIRU/34-71      AC Q2LM36.1
#=GS A0A027YSW2_ECOLX/1-41   AC A0A027YSW2.1
#=GS Q2LLQ5_9VIRU/34-75      AC Q2LLQ5.1
#=GS Q2LLZ3_9VIRU/34-75      AC Q2LLZ3.1
#=GS Q2LLU9_9VIRU/34-75      AC Q2LLU9.1
#=GS Q2LL28_BPAL3/34-73      AC Q2LL28.1
#=GS Q2LLW0_9VIRU/34-75      AC Q2LLW0.1
#=GS A0A028TJ36_ECOLX/26-67  AC A0A028TJ36.1
#=GS Q2LLB2_9VIRU/34-74      AC Q2LLB2.1
#=GS Q2LL90_9VIRU/34-75      AC Q2LL90.1
#=GS Q2LM97_9VIRU/34-71      AC Q2LM97.1
#=GS A3FJK3_BPPHX/34-75      AC A3FJK3.1
#=GS Q2LLE5_9VIRU/34-75      AC Q2LLE5.1
#=GS Q2LM57_9VIRU/34-71      AC Q2LM57.1
#=GS A3FJR9_BPPHX/34-75      AC A3FJR9.1
#=GS Q2LMB7_9VIRU/34-71      AC Q2LMB7.1
#=GS A0A027LYH9_ECOLX/1-41   AC A0A027LYH9.1
#=GS Q2LLD4_9VIRU/34-75      AC Q2LLD4.1
#=GS Q2LLK0_9VIRU/34-75      AC Q2LLK0.1
#=GS Q2LLG7_9VIRU/34-76      AC Q2LLG7.1
#=GS E1ANC5_BPPHX/34-75      AC E1ANC5.1
#=GS Q2LLN3_9VIRU/34-75      AC Q2LLN3.1
#=GS Q2LL57_9VIRU/34-75      AC Q2LL57.1
#=GS Q2LM15_9VIRU/34-75      AC Q2LM15.1
#=GS A3FJP7_BPPHX/34-75      AC A3FJP7.1
#=GS Q2LLM2_9VIRU/34-75      AC Q2LLM2.1
#=GS Q2LMC7_9VIRU/34-75      AC Q2LMC7.1
#=GS A3FJT0_BPPHX/34-75      AC A3FJT0.1
#=GS Q2LLA1_9VIRU/34-75      AC Q2LLA1.1
#=GS VGE_BPPHK/34-73         AC Q38040.1
#=GS F8RMX1_BPPHX/34-75      AC F8RMX1.1
#=GS Q2LLS7_9VIRU/34-75      AC Q2LLS7.1
#=GS A3FJB5_BPPHX/34-75      AC A3FJB5.1
#=GS Q2LM04_9VIRU/34-75      AC Q2LM04.1
#=GS W9B137_9MYCO/1-26       AC W9B137.1
#=GS A3FJC6_BPPHX/34-75      AC A3FJC6.1
#=GS A3FJA4_BPPHX/34-75      AC A3FJA4.1
#=GS Q2LM26_9VIRU/34-71      AC Q2LM26.1
#=GS A3FJJ2_BPPHX/34-75      AC A3FJJ2.1
#=GS I6ZR19_BPPHX/34-75      AC I6ZR19.1
#=GS Q2LMA7_9VIRU/34-71      AC Q2LMA7.1
#=GS VGE_BPAL3/34-73         AC P31280.1
#=GS D0U1A1_BPG4/34-75       AC D0U1A1.1
#=GS Q2LL68_9VIRU/34-76      AC Q2LL68.1
#=GS A0A026P7A9_ECOLX/26-67  AC A0A026P7A9.1
#=GS W4HQY6_MYCGS/1-26       AC W4HQY6.1
#=GS Q2LM46_9VIRU/34-76      AC Q2LM46.1
#=GS Q2LLT8_9VIRU/34-75      AC Q2LLT8.1
#=GS F8RN67_BPPHX/34-75      AC F8RN67.1
#=GS A0A026M6M1_ECOLX/26-67  AC A0A026M6M1.1
Q2LLI9_9VIRU/33-76                 .kpl--VSSWKVLSLPKTSSMVLNAQLRPLNCSPL-----------lfsfvpatktls..
Q2LLR6_9VIRU/34-75                 ....RPASSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLMF..............
Q2LLY2_9VIRU/34-75                 ....RPVSSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLTF..............
Q2LLL1_9VIRU/34-75                 ....RPASSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
L7TNY5_9VIRU/34-75                 qhvl----LWKAPNSPKILSMVLTSQLRPLNYSLLPCVYAPETLT-m.............
S5VLY4_9VIRU/34-75                 qhvl----LWKAPSSPKILSMVLTSQLRPLNYSLLPCVYAPETLT-m.............
VGE_BPG4/34-75                     ...p-PVSSWKVLSLPKTSSMVLNAPLKPLNCSPSLFLFAPET---kil...........
Q2LLX1_9VIRU/34-75                 ....RPVSSWKALSLRKTLLMASSVRLRPLSCSRLPCVYAQETLMF..............
Q8W6C5_BPG4/34-75                  ...p-PVSSWKVLSLPKTSSMVLNAPLKPLNCSPSLFLFAPET---kil...........
Q2LL79_9VIRU/34-75                 ...p-PVSLWKVLSLPKTSSMVLNAQLRPLNCSP------------shfsfapatktl..
D0U1B1_BPG4/34-75                  ...p-PVSSWKVLSLPKTSSMVLNAPLKPLNCSPSLFLFAPET---kil...........
S5VZD0_9VIRU/34-75                 qhvl----LWKAPSSPKILSMVLTSQLRPLNYSLLPCVYAPETLT-m.............
Q2LLP4_9VIRU/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
Q2LM77_9VIRU/34-71                 ....RPASSWKALSLRKTLLMASSVRLKPLSSSRTPCV--------lrpd..........
C6K2G5_BPST1/34-73                 .qha---SLWKARSLAKTLLMASSVRLTPLSSSRTPCVLRQD----sk............
A3FJD7_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
Q2LL46_9VIRU/34-75                 ....RHVLLWKALNSPKTSLMVSMPRLKPLNSSRLPCVYAPETLN-l.............
A0A025JF54_ECO57/1-41              ....-PVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
Q2LM87_9VIRU/34-71                 ....RPASSWKALSLRKTLLMASSVRLKPLSSSRTPCV--------lrpd..........
D0U139_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVQLKPLNCSRLPCVYAQETLTF..............
Q2LLF6_9VIRU/34-74                 ...p-PASSWKALSLPKTSSMVLNAQLKPLNCSPSLFSFAPE----tri...........
A3FJU1_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
F8RMM2_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
Q2LM67_9VIRU/34-71                 ....RPASSWKALSLRKTLLMVSSVRLKPLSSSRTPCV--------lkpd..........
A0A028SWC8_ECOLX/1-40              ....--VSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
Q2LLH8_9VIRU/33-76                 .kpl--VSSWKVLSLPKTSSMVLNAQLRPLNCSPL-----------lfsfvpatktls..
VGE_BPS13/34-75                    ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
A3FJQ8_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQEILTF..............
Q9G088_BPS13/34-75                 ....RPVSSWRALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
E_BPPHS/34-75                      ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
X5WR77_9RHIZ/1-26                  ....----------------MASSVRLKPLNCSRLPCVYAQETLTF..............
Q2LLC3_9VIRU/34-70                 ...l-PASSWKVLSLPKTSSMVLNAQLKPLNCS-------------pslfsfap......
Q5C8R8_9VIRU/34-74                 ...p-PASSWKALSLPKTSSMVLNAQLKPLNCSPSLFSFAPE----tki...........
F8RLU7_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVCAQETLTF..............
Q2LM36_9VIRU/34-71                 ....RPASSWKALSLRKTLLMASSVRLKPLSSSRTPCV--------lrpd..........
A0A027YSW2_ECOLX/1-41              ....-PVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
Q2LLQ5_9VIRU/34-75                 ....RPASSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLTF..............
Q2LLZ3_9VIRU/34-75                 ....RPVSSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLMF..............
Q2LLU9_9VIRU/34-75                 ....RPVSSWKALSLRKTLLMASSVRLRPLSCSRLPCVYAQETLMF..............
Q2LL28_BPAL3/34-73                 .qha---SLWKARSLAKTLSMASSARLTPLSSSRTPCVLKQD----sk............
Q2LLW0_9VIRU/34-75                 ....RPASSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLMF..............
A0A028TJ36_ECOLX/26-67             ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
Q2LLB2_9VIRU/34-74                 ...p-PASSWKALSLPKTSSMVLNAQLKPLNCSPSLFSFAPE----tki...........
Q2LL90_9VIRU/34-75                 ...p-PVSSWKVLSLPKTSSMVLNAQLRPLNCS-------------pslfsfapatktl.
Q2LM97_9VIRU/34-71                 ....RPASSWKALSLRKTLLMASSVRLKPLSSSRTPCV--------lrpd..........
A3FJK3_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLMF..............
Q2LLE5_9VIRU/34-75                 ...p-PASSWKVLSLPKTSSMVLNAQLKPLNCSPSLFLFAPET---kil...........
Q2LM57_9VIRU/34-71                 ...q-PASSWRALSLRKTLLMASSVRLKPLNSSRTPCV--------lkpd..........
A3FJR9_BPPHX/34-75                 ....RPVSSWKALNLRKTLLIASSVRLKPLNCSRLPCVYAQEILTF..............
Q2LMB7_9VIRU/34-71                 ....RPASSWKARSLQKILLMASSVRLKPLSSSRIPCV--------lrpd..........
A0A027LYH9_ECOLX/1-41              ....-PVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
Q2LLD4_9VIRU/34-75                 ...l-PASSWKVLSLPKTSSMVLNAQLKPLNCS-------------pslfsfapatktl.
Q2LLK0_9VIRU/34-75                 ....RPVSSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLMF..............
Q2LLG7_9VIRU/34-76                 ...p-PVSSWKVLSLPKTSSMVLNAQLRPLNCS-------------pslfsfvpatktls
E1ANC5_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
Q2LLN3_9VIRU/34-75                 ....RPASSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLTF..............
Q2LL57_9VIRU/34-75                 ....RHVLLWKALNSPKTSLMVSMPRLKPLNSSRLPCVYAPETLS-l.............
Q2LM15_9VIRU/34-75                 ....RPVSSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLTF..............
A3FJP7_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKLLNCSRLPCVYAQETLTF..............
Q2LLM2_9VIRU/34-75                 ....RPASSWKALSLRKTLLMASSVRLRPLSCSRLPCVYAQETLTF..............
Q2LMC7_9VIRU/34-75                 qhvl----LWKAPSSPKILSMVLTSQLRPLNYSLLPCVYAPETLT-m.............
A3FJT0_BPPHX/34-75                 ....RPVSSWKALNLRKTLLIASSVRLKPLNCSRLPCVYAQEILTF..............
Q2LLA1_9VIRU/34-75                 ...p-PVSSWKVLSLPKTSSMVLNAQLRPLNCS-------------pslfsfapatktl.
VGE_BPPHK/34-73                    .qha---SLWKARSLAKTLLMASSARLTPLSSSRTPCVLRQD----sk............
F8RMX1_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
Q2LLS7_9VIRU/34-75                 ....RPASSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLMF..............
A3FJB5_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
Q2LM04_9VIRU/34-75                 ....RPASSWKALNLRKTLLMVSSVRLKPLNCSRLPCVYAQETLTF..............
W9B137_9MYCO/1-26                  ....----------------MASSVRLKPLNCSRLPCVYAQETLTF..............
A3FJC6_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMALSVRLKPLNCSRLPCVYAQETLTF..............
A3FJA4_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
Q2LM26_9VIRU/34-71                 ....RPVSSWKALSLRRTLLMASNVRLKPLNSLRTPCV--------lrld..........
A3FJJ2_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
I6ZR19_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQEALTF..............
Q2LMA7_9VIRU/34-71                 ....RPASSWKALSLRKTLLMASSVRLKPLSSSRTPCV--------lrld..........
VGE_BPAL3/34-73                    .qha---SLWKARSLAKTLSMASSARLTPLSSSRTPCVLKQD----sk............
D0U1A1_BPG4/34-75                  ...p-PVSSWKVLSLPKTSSMVLNAPLKPLNCSPSLFLFAPET---kil...........
Q2LL68_9VIRU/34-76                 ....RPVLSWKVQSLPKTSLMVSNALLRPPNCSPLLFSFVPETKT-ll............
A0A026P7A9_ECOLX/26-67             ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
W4HQY6_MYCGS/1-26                  ....----------------MASSVRLKPLNCSRLPCVYAQETLTF..............
Q2LM46_9VIRU/34-76                 ....RPVLSWKVQSLPKTSLMVSNALLRPPNCSPLLFSFVPETKT-ll............
Q2LLT8_9VIRU/34-75                 ....RPVSSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLTF..............
F8RN67_BPPHX/34-75                 ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
A0A026M6M1_ECOLX/26-67             ....RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF..............
#=GC seq_cons                      ....RPVSSWKALsLRKTLLMASSVRLKPLNCSRLPCVYAQETLh...............
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