GenomeNet

Database: Pfam
Entry: Microvir_lysis
LinkDB: Microvir_lysis
Original site: Microvir_lysis 
#=GF ID   Microvir_lysis
#=GF AC   PF04517.7
#=GF DE   Microvirus lysis protein (E), C terminus
#=GF AU   Kerrison ND
#=GF SE   DOMO:DM04358;
#=GF GA   25.00 25.00;
#=GF TC   50.50 49.90;
#=GF NC   17.30 15.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12100551
#=GF RT   The Escherichia coli FKBP-type PPIase SlyD is required for the
#=GF RT   stabilization of the E lysis protein of bacteriophage phiX174. 
#=GF RA   Bernhardt TG, Roof WD, Young R; 
#=GF RL   Mol Microbiol 2002;45:99-108.
#=GF DR   INTERPRO; IPR007605;
#=GF CC   E protein causes host cell lysis by inhibiting MraY, a
#=GF CC   peptidoglycan biosynthesis enzyme.  This leads to cell wall
#=GF CC   failure at septation [1]. The N terminal transmembrane region
#=GF CC   matches the signal peptide model and must be omitted from the
#=GF CC   family.
#=GF SQ   70
#=GS Q2LLR6_9VIRU/34-75  AC Q2LLR6.1
#=GS Q2LLY2_9VIRU/34-75  AC Q2LLY2.1
#=GS Q2LLL1_9VIRU/34-75  AC Q2LLL1.1
#=GS Q2LLI9_9VIRU/34-75  AC Q2LLI9.1
#=GS VGE_BPG4/34-75      AC P03640.1
#=GS Q2LLX1_9VIRU/34-75  AC Q2LLX1.1
#=GS C6K2G5_BPST1/34-75  AC C6K2G5.1
#=GS Q8W6C5_BPG4/34-75   AC Q8W6C5.1
#=GS Q2LL79_9VIRU/34-75  AC Q2LL79.1
#=GS D0U1B1_BPG4/34-75   AC D0U1B1.1
#=GS Q2LLP4_9VIRU/34-75  AC Q2LLP4.1
#=GS A3FJD7_BPPHX/34-75  AC A3FJD7.1
#=GS Q2LL46_9VIRU/34-75  AC Q2LL46.1
#=GS D0U139_BPPHX/34-75  AC D0U139.1
#=GS A3FJU1_BPPHX/34-75  AC A3FJU1.1
#=GS Q2LM77_9VIRU/34-75  AC Q2LM77.1
#=GS F8RMM2_BPPHX/34-75  AC F8RMM2.1
#=GS Q2LL28_BPAL3/34-75  AC Q2LL28.1
#=GS VGE_BPS13/34-75     AC P07930.2
#=GS Q2LLB2_9VIRU/34-75  AC Q2LLB2.1
#=GS A3FJQ8_BPPHX/34-75  AC A3FJQ8.1
#=GS Q9G088_BPS13/34-75  AC Q9G088.1
#=GS E_BPPHX/34-75       AC P03639.2
#=GS Q2LMB7_9VIRU/34-74  AC Q2LMB7.1
#=GS F8RLU7_BPPHX/34-75  AC F8RLU7.1
#=GS Q5C8R8_9VIRU/34-75  AC Q5C8R8.1
#=GS Q2LLQ5_9VIRU/34-75  AC Q2LLQ5.1
#=GS Q2LLZ3_9VIRU/34-75  AC Q2LLZ3.1
#=GS Q2LLG7_9VIRU/34-75  AC Q2LLG7.1
#=GS Q2LLU9_9VIRU/34-75  AC Q2LLU9.1
#=GS Q2LLW0_9VIRU/34-75  AC Q2LLW0.1
#=GS Q2LL90_9VIRU/34-75  AC Q2LL90.1
#=GS A3FJK3_BPPHX/34-75  AC A3FJK3.1
#=GS Q2LLC3_9VIRU/34-75  AC Q2LLC3.1
#=GS Q2LLE5_9VIRU/34-75  AC Q2LLE5.1
#=GS A3FJR9_BPPHX/34-75  AC A3FJR9.1
#=GS Q2LM67_9VIRU/34-74  AC Q2LM67.1
#=GS Q2LM97_9VIRU/34-75  AC Q2LM97.1
#=GS Q2LM26_9VIRU/34-75  AC Q2LM26.1
#=GS Q2LLD4_9VIRU/34-75  AC Q2LLD4.1
#=GS Q2LLK0_9VIRU/34-75  AC Q2LLK0.1
#=GS Q2LM87_9VIRU/34-75  AC Q2LM87.1
#=GS E1ANC5_BPPHX/34-75  AC E1ANC5.1
#=GS Q2LLN3_9VIRU/34-75  AC Q2LLN3.1
#=GS Q2LL57_9VIRU/34-75  AC Q2LL57.1
#=GS Q2LL68_9VIRU/34-75  AC Q2LL68.1
#=GS Q2LLH8_9VIRU/34-75  AC Q2LLH8.1
#=GS Q2LM15_9VIRU/34-75  AC Q2LM15.1
#=GS A3FJP7_BPPHX/34-75  AC A3FJP7.1
#=GS Q2LLM2_9VIRU/34-75  AC Q2LLM2.1
#=GS Q2LMC7_9VIRU/34-75  AC Q2LMC7.1
#=GS A3FJT0_BPPHX/34-75  AC A3FJT0.1
#=GS Q2LMA7_9VIRU/34-75  AC Q2LMA7.1
#=GS Q2LLA1_9VIRU/34-75  AC Q2LLA1.1
#=GS F8RMX1_BPPHX/34-75  AC F8RMX1.1
#=GS Q2LLS7_9VIRU/34-75  AC Q2LLS7.1
#=GS A3FJB5_BPPHX/34-75  AC A3FJB5.1
#=GS Q2LM04_9VIRU/34-75  AC Q2LM04.1
#=GS Q2LM46_9VIRU/34-75  AC Q2LM46.1
#=GS A3FJC6_BPPHX/34-75  AC A3FJC6.1
#=GS A3FJA4_BPPHX/34-75  AC A3FJA4.1
#=GS A3FJJ2_BPPHX/34-75  AC A3FJJ2.1
#=GS Q2LM57_9VIRU/34-75  AC Q2LM57.1
#=GS D0U1A1_BPG4/34-75   AC D0U1A1.1
#=GS Q2LLF6_9VIRU/34-75  AC Q2LLF6.1
#=GS VGE_BPAL3/34-75     AC P31280.1
#=GS Q2LLT8_9VIRU/34-75  AC Q2LLT8.1
#=GS VGE_BPPHK/34-75     AC Q38040.1
#=GS F8RN67_BPPHX/34-75  AC F8RN67.1
#=GS Q2LM36_9VIRU/34-75  AC Q2LM36.1
Q2LLR6_9VIRU/34-75             ..RPASSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLMF.
Q2LLY2_9VIRU/34-75             ..RPVSSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLTF.
Q2LLL1_9VIRU/34-75             ..RPASSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF.
Q2LLI9_9VIRU/34-75             pl--VSSWKVLSLPKTSSMVLNAQLRPLNCSPLLFSFVPATKTL.
VGE_BPG4/34-75                 ..PPVSSWKVLSLPKTSSMVLNAPLKPLNCSPSLFLFAPETKIL.
Q2LLX1_9VIRU/34-75             ..RPVSSWKALSLRKTLLMASSVRLRPLSCSRLPCVYAQETLMF.
C6K2G5_BPST1/34-75             ..QHASLWKARSLAKTLLMASSVRLTPLSSSRTPCVLRQDSKKL.
Q8W6C5_BPG4/34-75              ..PPVSSWKVLSLPKTSSMVLNAPLKPLNCSPSLFLFAPETKIL.
Q2LL79_9VIRU/34-75             ..PPVSLWKVLSLPKTSSMVLNAQLRPLNCSPSHFSFAPATKTL.
D0U1B1_BPG4/34-75              ..PPVSSWKVLSLPKTSSMVLNAPLKPLNCSPSLFLFAPETKIL.
Q2LLP4_9VIRU/34-75             ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF.
A3FJD7_BPPHX/34-75             ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF.
Q2LL46_9VIRU/34-75             ..RHVLLWKALNSPKTSLMVSMPRLKPLNSSRLPCVYAPETLNL.
D0U139_BPPHX/34-75             ..RPVSSWKALNLRKTLLMASSVQLKPLNCSRLPCVYAQETLTF.
A3FJU1_BPPHX/34-75             ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF.
Q2LM77_9VIRU/34-75             ..RPASSWKALSLRKTLLMASSVRLKPLSSSRTPCVLRPDSKK-r
F8RMM2_BPPHX/34-75             ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF.
Q2LL28_BPAL3/34-75             ..QHASLWKARSLAKTLSMASSARLTPLSSSRTPCVLKQDSKKL.
VGE_BPS13/34-75                ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF.
Q2LLB2_9VIRU/34-75             ..PPASSWKALSLPKTSSMVLNAQLKPLNCSPSLFSFAPETKIL.
A3FJQ8_BPPHX/34-75             ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQEILTF.
Q9G088_BPS13/34-75             ..RPVSSWRALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF.
E_BPPHX/34-75                  ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF.
Q2LMB7_9VIRU/34-74             ..RPASSWKARSLQKILLMASSVRLKPLSSSRIPCVLRPDSK--r
F8RLU7_BPPHX/34-75             ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVCAQETLTF.
Q5C8R8_9VIRU/34-75             ..PPASSWKALSLPKTSSMVLNAQLKPLNCSPSLFSFAPETKIL.
Q2LLQ5_9VIRU/34-75             ..RPASSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLTF.
Q2LLZ3_9VIRU/34-75             ..RPVSSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLMF.
Q2LLG7_9VIRU/34-75             ..PPVSSWKVLSLPKTSSMVLNAQLRPLNCSPSLFSFVPATKTL.
Q2LLU9_9VIRU/34-75             ..RPVSSWKALSLRKTLLMASSVRLRPLSCSRLPCVYAQETLMF.
Q2LLW0_9VIRU/34-75             ..RPASSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLMF.
Q2LL90_9VIRU/34-75             ..PPVSSWKVLSLPKTSSMVLNAQLRPLNCSPSLFSFAPATKTL.
A3FJK3_BPPHX/34-75             ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLMF.
Q2LLC3_9VIRU/34-75             .l-PASSWKVLSLPKTSSMVLNAQLKPLNCSPSLFSFAPATKIL.
Q2LLE5_9VIRU/34-75             ..PPASSWKVLSLPKTSSMVLNAQLKPLNCSPSLFLFAPETKIL.
A3FJR9_BPPHX/34-75             ..RPVSSWKALNLRKTLLIASSVRLKPLNCSRLPCVYAQEILTF.
Q2LM67_9VIRU/34-74             ..RPASSWKALSLRKTLLMVSSVRLKPLSSSRTPCVLKPDSK--r
Q2LM97_9VIRU/34-75             ..RPASSWKALSLRKTLLMASSVRLKPLSSSRTPCVLRPDSKK-r
Q2LM26_9VIRU/34-75             ..RPVSSWKALSLRRTLLMASNVRLKPLNSLRTPCVLRLDSKK-r
Q2LLD4_9VIRU/34-75             .l-PASSWKVLSLPKTSSMVLNAQLKPLNCSPSLFSFAPATKTL.
Q2LLK0_9VIRU/34-75             ..RPVSSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLMF.
Q2LM87_9VIRU/34-75             ..RPASSWKALSLRKTLLMASSVRLKPLSSSRTPCVLRPDSKK-r
E1ANC5_BPPHX/34-75             ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF.
Q2LLN3_9VIRU/34-75             ..RPASSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLTF.
Q2LL57_9VIRU/34-75             ..RHVLLWKALNSPKTSLMVSMPRLKPLNSSRLPCVYAPETLSL.
Q2LL68_9VIRU/34-75             ..RPVLSWKVQSLPKTSLMVSNALLRPPNCSPLLFSFVPETKTL.
Q2LLH8_9VIRU/34-75             pl--VSSWKVLSLPKTSSMVLNAQLRPLNCSPLLFSFVPATKTL.
Q2LM15_9VIRU/34-75             ..RPVSSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLTF.
A3FJP7_BPPHX/34-75             ..RPVSSWKALNLRKTLLMASSVRLKLLNCSRLPCVYAQETLTF.
Q2LLM2_9VIRU/34-75             ..RPASSWKALSLRKTLLMASSVRLRPLSCSRLPCVYAQETLTF.
Q2LMC7_9VIRU/34-75             ..QHVLLWKAPSSPKILSMVLTSQLRPLNYSLLPCVYAPETLTM.
A3FJT0_BPPHX/34-75             ..RPVSSWKALNLRKTLLIASSVRLKPLNCSRLPCVYAQEILTF.
Q2LMA7_9VIRU/34-75             ..RPASSWKALSLRKTLLMASSVRLKPLSSSRTPCVLRLDSKK-r
Q2LLA1_9VIRU/34-75             ..PPVSSWKVLSLPKTSSMVLNAQLRPLNCSPSLFSFAPATKTL.
F8RMX1_BPPHX/34-75             ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF.
Q2LLS7_9VIRU/34-75             ..RPASSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLMF.
A3FJB5_BPPHX/34-75             ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF.
Q2LM04_9VIRU/34-75             ..RPASSWKALNLRKTLLMVSSVRLKPLNCSRLPCVYAQETLTF.
Q2LM46_9VIRU/34-75             ..RPVLSWKVQSLPKTSLMVSNALLRPPNCSPLLFSFVPETKTL.
A3FJC6_BPPHX/34-75             ..RPVSSWKALNLRKTLLMALSVRLKPLNCSRLPCVYAQETLTF.
A3FJA4_BPPHX/34-75             ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF.
A3FJJ2_BPPHX/34-75             ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF.
Q2LM57_9VIRU/34-75             ..QPASSWRALSLRKTLLMASSVRLKPLNSSRTPCVLKPDLKK-r
D0U1A1_BPG4/34-75              ..PPVSSWKVLSLPKTSSMVLNAPLKPLNCSPSLFLFAPETKIL.
Q2LLF6_9VIRU/34-75             ..PPASSWKALSLPKTSSMVLNAQLKPLNCSPSLFSFAPETRIL.
VGE_BPAL3/34-75                ..QHASLWKARSLAKTLSMASSARLTPLSSSRTPCVLKQDSKKL.
Q2LLT8_9VIRU/34-75             ..RPVSSWKALSLRKTLLMASSVRLRPLNCSRLPCVYAQETLTF.
VGE_BPPHK/34-75                ..QHASLWKARSLAKTLLMASSARLTPLSSSRTPCVLRQDSKKL.
F8RN67_BPPHX/34-75             ..RPVSSWKALNLRKTLLMASSVRLKPLNCSRLPCVYAQETLTF.
Q2LM36_9VIRU/34-75             ..RPASSWKALSLRKTLLMASSVRLKPLSSSRTPCVLRPDSKK-r
#=GC seq_cons                  ..RPVSSWKALSLRKTLLMASSVRLKPLNCSRLPCVaA.EThph.
//
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