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Database: Pfam
Entry: MobC
LinkDB: MobC
Original site: MobC 
#=GF ID   MobC
#=GF AC   PF05713.10
#=GF DE   Bacterial mobilisation protein (MobC)
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_2832 (release 8.0)
#=GF GA   22.20 22.20;
#=GF TC   22.20 22.20;
#=GF NC   22.10 22.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11976306
#=GF RT   Characterization of two cryptic Helicobacter pylori plasmids: a
#=GF RT   putative source for horizontal gene transfer and gene shuffling. 
#=GF RA   Hofreuter D, Haas R; 
#=GF RL   J Bacteriol 2002;184:2755-2766.
#=GF RN   [2]
#=GF RM   9302013
#=GF RT   The relaxosome protein MobC promotes conjugal plasmid
#=GF RT   mobilization by extending DNA strand separation to the nick site
#=GF RT   at the origin of transfer. 
#=GF RA   Zhang S, Meyer R; 
#=GF RL   Mol Microbiol 1997;25:509-516.
#=GF DR   INTERPRO; IPR008687;
#=GF CC   This family consists of several bacterial MobC-like,
#=GF CC   mobilisation proteins. MobC proteins belong to the group of
#=GF CC   relaxases. Together with MobA and MobB they bind to a single
#=GF CC   cis-active site of a mobilising plasmid, the origin of transfer
#=GF CC   (oriT) region [1]. The absence of MobC has several different
#=GF CC   effects on oriT DNA. Site- and strand-specific nicking by MobA
#=GF CC   protein is severely reduced, accounting for the lower frequency
#=GF CC   of mobilisation. The localised DNA strand separation required
#=GF CC   for this nicking is less affected, but becomes more sensitive to
#=GF CC   the level of active DNA gyrase in the cell. In addition, strand
#=GF CC   separation is not efficiently extended through the region
#=GF CC   containing the nick site. These effects suggest a model in which
#=GF CC   MobC acts as a molecular wedge for the relaxosome-induced
#=GF CC   melting of oriT DNA. The effect of MobC on strand separation may
#=GF CC   be partially complemented by the helical distortion induced by
#=GF CC   supercoiling. However, MobC extends the melted region through
#=GF CC   the nick site, thus providing the single-stranded substrate
#=GF CC   required for cleavage by MobA [2].
#=GF SQ   1437
#=GS A4CGM8_ROBBH/66-108       AC A4CGM8.1
#=GS C7H3N1_9FIRM/60-103       AC C7H3N1.1
#=GS D4K1U1_9FIRM/83-121       AC D4K1U1.1
#=GS A0A0S2W761_9FIRM/72-114   AC A0A0S2W761.1
#=GS E2ZN32_9FIRM/54-96        AC E2ZN32.1
#=GS A0A0B8SYW3_9SPHI/76-125   AC A0A0B8SYW3.1
#=GS U2CFL2_9CLOT/59-102       AC U2CFL2.1
#=GS D9Y1K9_9ACTN/108-155      AC D9Y1K9.1
#=GS S0IPR1_9FIRM/60-100       AC S0IPR1.1
#=GS V4SPA9_STRIN/65-106       AC V4SPA9.1
#=GS R9N1Z1_9FIRM/69-110       AC R9N1Z1.1
#=GS W7UJM2_RUMFL/66-110       AC W7UJM2.1
#=GS D4IKK1_9BACT/72-115       AC D4IKK1.1
#=GS A0A0Q9RCC1_9MICC/30-73    AC A0A0Q9RCC1.1
#=GS R8W123_9CLOT/57-102       AC R8W123.1
#=GS B2JC06_NOSP7/81-136       AC B2JC06.1
#=GS D4M3I9_9FIRM/54-103       AC D4M3I9.1
#=GS B7K6N2_CYAP8/67-94        AC B7K6N2.1
#=GS R7N4C7_9FIRM/63-108       AC R7N4C7.1
#=GS A0A0Q5P6V4_9BURK/69-113   AC A0A0Q5P6V4.1
#=GS V2XT68_9FIRM/78-123       AC V2XT68.1
#=GS C6RGU8_9PROT/2-46         AC C6RGU8.1
#=GS G0HF26_CORVD/79-124       AC G0HF26.1
#=GS R9IU14_9FIRM/70-117       AC R9IU14.1
#=GS D4M204_9FIRM/71-120       AC D4M204.1
#=GS D3AK49_9CLOT/59-102       AC D3AK49.1
#=GS R7JFG9_9PORP/72-115       AC R7JFG9.1
#=GS B9D154_CAMRE/61-113       AC B9D154.1
#=GS A5VGY8_SPHWW/112-160      AC A5VGY8.1
#=GS C4GE66_9FIRM/57-104       AC C4GE66.1
#=GS A0A086XTP0_9RHOB/114-153  AC A0A086XTP0.1
#=GS R6VXK0_9FIRM/52-98        AC R6VXK0.1
#=GS E9S781_RUMAL/52-95        AC E9S781.1
#=GS A0A069DL42_9BACL/65-110   AC A0A069DL42.1
#=GS A0A126NXA5_9BRAD/69-112   AC A0A126NXA5.1
#=GS V7EF21_9RHOB/69-117       AC V7EF21.1
#=GS A0A099J311_9MICO/99-136   AC A0A099J311.1
#=GS A0A0N7MB57_9RHOB/99-145   AC A0A0N7MB57.1
#=GS A0A0P8W5J0_9CLOT/61-110   AC A0A0P8W5J0.1
#=GS C7H2R6_9FIRM/58-98        AC C7H2R6.1
#=GS E3GPA0_EUBLK/78-136       AC E3GPA0.1
#=GS A0A101WEW2_9FIRM/56-99    AC A0A101WEW2.1
#=GS A0A069JT07_9ACTN/113-160  AC A0A069JT07.1
#=GS A0A031LG78_9GAMM/81-131   AC A0A031LG78.1
#=GS R6TNL5_9CLOT/54-98        AC R6TNL5.1
#=GS A0A0L6U1R9_9FIRM/39-83    AC A0A0L6U1R9.1
#=GS R7AEW4_9CLOT/57-102       AC R7AEW4.1
#=GS B2JC20_NOSP7/81-136       AC B2JC20.1
#=GS C0MCH8_STRS7/57-104       AC C0MCH8.1
#=GS E1VRH1_GLUAR/83-126       AC E1VRH1.1
#=GS A0A0D6TPL8_9FLAO/65-112   AC A0A0D6TPL8.1
#=GS J5H5I6_9FIRM/180-227      AC J5H5I6.1
#=GS A3DKF2_CLOTH/53-92        AC A3DKF2.1
#=GS A7ZBW4_CAMC1/69-110       AC A7ZBW4.1
#=GS G2IU41_9SPHN/120-158      AC G2IU41.1
#=GS D4H4Q4_DENA2/88-124       AC D4H4Q4.1
#=GS E0NMM2_9FIRM/61-104       AC E0NMM2.1
#=GS A0A133YKB4_9FIRM/21-63    AC A0A133YKB4.1
#=GS A0A0B7H3E8_9FLAO/89-134   AC A0A0B7H3E8.1
#=GS N1MTA8_9SPHN/85-125       AC N1MTA8.1
#=GS M2Q4B8_9FIRM/63-112       AC M2Q4B8.1
#=GS V2YAY6_9FIRM/70-128       AC V2YAY6.1
#=GS D4L2K1_9FIRM/53-108       AC D4L2K1.1
#=GS J5UC12_9FIRM/57-104       AC J5UC12.1
#=GS E2ZFR5_9FIRM/59-100       AC E2ZFR5.1
#=GS A0A101NPX2_9ACTN/39-88    AC A0A101NPX2.1
#=GS F7V1W5_CLOSS/65-116       AC F7V1W5.1
#=GS C7H8P9_9FIRM/59-103       AC C7H8P9.1
#=GS R9M1K6_9FIRM/59-103       AC R9M1K6.1
#=GS R9L230_9FIRM/51-95        AC R9L230.1
#=GS Q0FUC9_PELBH/106-134      AC Q0FUC9.1
#=GS R9KQL7_9FIRM/70-115       AC R9KQL7.1
#=GS A0A010PIF9_9MICC/55-99    AC A0A010PIF9.1
#=GS E2ZEH9_9FIRM/84-123       AC E2ZEH9.1
#=GS T0IZ92_9SPHN/120-158      AC T0IZ92.1
#=GS A0A061QK85_9PROT/71-106   AC A0A061QK85.1
#=GS D3LWZ1_9FIRM/57-104       AC D3LWZ1.1
#=GS R6PPQ0_9CLOT/79-124       AC R6PPQ0.1
#=GS A0A0F4P5F1_PSEO7/72-114   AC A0A0F4P5F1.1
#=GS D4JA94_9FIRM/65-102       AC D4JA94.1
#=GS I4EB25_METSZ/109-159      AC I4EB25.1
#=GS K9UE41_9CYAN/75-131       AC K9UE41.1
#=GS R7E8Z8_9BACE/76-119       AC R7E8Z8.1
#=GS R9IVR6_9FIRM/70-117       AC R9IVR6.1
#=GS A0A0M2NGP9_9FIRM/56-95    AC A0A0M2NGP9.1
#=GS V2YG87_9FIRM/79-129       AC V2YG87.1
#=GS D4MPJ5_9FIRM/57-102       AC D4MPJ5.1
#=GS A0A0N7JI81_9CAUL/108-150  AC A0A0N7JI81.1
#=GS R9MMY1_9FIRM/61-113       AC R9MMY1.1
#=GS A0A0W0TH10_9GAMM/62-110   AC A0A0W0TH10.1
#=GS D3Q2W1_STANL/80-123       AC D3Q2W1.1
#=GS E2ZJD6_9FIRM/83-121       AC E2ZJD6.1
#=GS J1JZ14_9RHIZ/62-106       AC J1JZ14.1
#=GS B9YBU1_9FIRM/80-122       AC B9YBU1.1
#=GS A0A0Q5UCH1_9SPHI/87-129   AC A0A0Q5UCH1.1
#=GS N2B142_9CLOT/70-118       AC N2B142.1
#=GS I3U5U5_ENTFC/108-154      AC I3U5U5.1
#=GS B0S1X0_FINM2/61-104       AC B0S1X0.1
#=GS A0A0D6KFI7_9CYAN/90-140   AC A0A0D6KFI7.1
#=GS G2T4N5_ROSHA/183-225      AC G2T4N5.1
#=GS A7HZD0_CAMHC/57-98        AC A7HZD0.1
#=GS R9M6P1_9FIRM/53-97        AC R9M6P1.1
#=GS A5N4V0_CLOK5/61-109       AC A5N4V0.1
#=GS W3AN28_9FIRM/58-110       AC W3AN28.1
#=GS D4W978_9FIRM/62-107       AC D4W978.1
#=GS A0A0P1H270_9RHOB/76-112   AC A0A0P1H270.1
#=GS H8XSU6_FLAIG/65-106       AC H8XSU6.1
#=GS V2ZE63_9FIRM/95-140       AC V2ZE63.1
#=GS R9N1U1_9FIRM/70-117       AC R9N1U1.1
#=GS F0H2Q2_9FIRM/61-104       AC F0H2Q2.1
#=GS A0A059W9L2_STRA9/147-195  AC A0A059W9L2.1
#=GS A0A060R9M9_9BACT/81-124   AC A0A060R9M9.1
#=GS A3X864_9RHOB/38-86        AC A3X864.1
#=GS J6HFF6_9FIRM/60-101       AC J6HFF6.1
#=GS U7UNF7_9FIRM/57-104       AC U7UNF7.1
#=GS A0A126RX88_9SPHN/116-154  AC A0A126RX88.1
#=GS A0A137ST03_9FIRM/23-72    AC A0A137ST03.1
#=GS H0I178_9RHIZ/55-97        AC H0I178.1
#=GS Q4JTW0_CORJK/70-110       AC Q4JTW0.1
#=GS G9YUC3_9FIRM/76-120       AC G9YUC3.1
#=GS Q1QRV9_NITHX/71-114       AC Q1QRV9.1
#=GS R9J2Q6_9FIRM/64-117       AC R9J2Q6.1
#=GS B7RKC1_9RHOB/4-41         AC B7RKC1.1
#=GS J6HH40_9FIRM/59-103       AC J6HH40.1
#=GS R5EM74_9FIRM/2-39         AC R5EM74.1
#=GS A0A0P4V8J1_9CYAN/84-128   AC A0A0P4V8J1.1
#=GS A0A060RCZ0_9BACT/54-99    AC A0A060RCZ0.1
#=GS C7H9F1_9FIRM/59-100       AC C7H9F1.1
#=GS U2LHA1_9BACT/72-115       AC U2LHA1.1
#=GS V6KAU0_STRRC/130-175      AC V6KAU0.1
#=GS C7RGW1_ANAPD/61-104       AC C7RGW1.1
#=GS D4KYE9_9FIRM/59-103       AC D4KYE9.1
#=GS B9YBX5_9FIRM/65-110       AC B9YBX5.1
#=GS D4L0I1_9FIRM/66-107       AC D4L0I1.1
#=GS T0GJB7_9SPHN/116-154      AC T0GJB7.1
#=GS R9J160_9FIRM/70-117       AC R9J160.1
#=GS A0A142HUH5_9SPHI/79-121   AC A0A142HUH5.1
#=GS R9IQD0_9FIRM/59-100       AC R9IQD0.1
#=GS A0A099BWA5_9BACT/70-114   AC A0A099BWA5.1
#=GS R9MWX6_9FIRM/60-100       AC R9MWX6.1
#=GS U7UQE9_9FIRM/61-104       AC U7UQE9.1
#=GS R6RGE7_9FIRM/48-92        AC R6RGE7.1
#=GS U2DRV2_CLOS4/71-119       AC U2DRV2.1
#=GS R6LLG8_9FIRM/53-97        AC R6LLG8.1
#=GS R5ADX2_9CLOT/60-112       AC R5ADX2.1
#=GS A6LE49_PARD8/75-105       AC A6LE49.1
#=GS A0A0B2AIB8_9ACTN/19-66    AC A0A0B2AIB8.1
#=GS R9IKB9_9FIRM/59-103       AC R9IKB9.1
#=GS R5E9P9_9CLOT/57-102       AC R5E9P9.1
#=GS H1Y5M5_9SPHI/68-116       AC H1Y5M5.1
#=GS Q0AM78_MARMM/66-108       AC Q0AM78.1
#=GS B4RFV6_PHEZH/112-156      AC B4RFV6.1
#=GS R9KSG2_9FIRM/64-109       AC R9KSG2.1
#=GS F0H3D1_9FIRM/61-104       AC F0H3D1.1
#=GS R6FQP6_9BACE/67-110       AC R6FQP6.1
#=GS A0A0D4CI48_9LACO/114-144  AC A0A0D4CI48.1
#=GS A0A0A2DY99_9PORP/72-117   AC A0A0A2DY99.1
#=GS A0A099VW19_9HELI/54-99    AC A0A099VW19.1
#=GS R5S133_9FIRM/60-105       AC R5S133.1
#=GS R9IU75_9FIRM/59-100       AC R9IU75.1
#=GS R9J734_9FIRM/59-103       AC R9J734.1
#=GS A0A0C2UXD9_9BACL/56-103   AC A0A0C2UXD9.1
#=GS R5C6L6_9FIRM/57-103       AC R5C6L6.1
#=GS G9RNZ3_9FIRM/59-111       AC G9RNZ3.1
#=GS G6ELI1_9SPHN/116-154      AC G6ELI1.1
#=GS A0A0Q7D4V1_9CAUL/108-136  AC A0A0Q7D4V1.1
#=GS T1CXX3_9HELI/152-194      AC T1CXX3.1
#=GS Q7MVZ9_PORGI/72-115       AC Q7MVZ9.1
#=GS R6NH79_9CLOT/55-87        AC R6NH79.1
#=GS U7G6T7_9RHOB/50-91        AC U7G6T7.1
#=GS R9IYA8_9FIRM/69-107       AC R9IYA8.1
#=GS L1KNW7_9ACTN/80-123       AC L1KNW7.1
#=GS L8TJW9_9MICC/44-87        AC L8TJW9.1
#=GS R7L2F3_9FIRM/60-98        AC R7L2F3.1
#=GS A0A133XT15_9ACTN/68-121   AC A0A133XT15.1
#=GS A0A095XF88_9FIRM/61-104   AC A0A095XF88.1
#=GS I2N385_9ACTN/112-165      AC I2N385.1
#=GS A0A0Q8QFM7_9SPHN/116-154  AC A0A0Q8QFM7.1
#=GS K9X871_9NOST/82-131       AC K9X871.1
#=GS H1HPN8_9BACT/70-114       AC H1HPN8.1
#=GS G2JBG3_9BURK/70-113       AC G2JBG3.1
#=GS G9RSK5_9FIRM/59-103       AC G9RSK5.1
#=GS V5SH98_9RHIZ/49-75        AC V5SH98.1
#=GS A0A089LR14_9BACL/56-103   AC A0A089LR14.1
#=GS A0A0R1ZKV7_9LACO/77-121   AC A0A0R1ZKV7.1
#=GS F7K6S6_9FIRM/59-104       AC F7K6S6.1
#=GS L2F4Z0_9GAMM/66-112       AC L2F4Z0.1
#=GS E8UDK4_TAYEM/124-156      AC E8UDK4.1
#=GS J1RNL5_9ACTN/60-109       AC J1RNL5.1
#=GS A0A095XC88_9FIRM/61-104   AC A0A095XC88.1
#=GS A0A132GKY0_9BACT/100-143  AC A0A132GKY0.1
#=GS A0A133YFR7_9FIRM/63-109   AC A0A133YFR7.1
#=GS A0A0B5EAZ6_9RHOB/114-142  AC A0A0B5EAZ6.1
#=GS L1L0S3_9ACTN/160-205      AC L1L0S3.1
#=GS C7H3G1_9FIRM/83-121       AC C7H3G1.1
#=GS R5QE94_9FIRM/59-102       AC R5QE94.1
#=GS R5A1K8_9CLOT/54-98        AC R5A1K8.1
#=GS R9J0B0_9FIRM/61-100       AC R9J0B0.1
#=GS A0A0Q5WVP3_9RHIZ/59-105   AC A0A0Q5WVP3.1
#=GS J6UC39_9RHOB/31-71        AC J6UC39.1
#=GS D7GT69_9FIRM/70-119       AC D7GT69.1
#=GS K9X8S8_9NOST/67-115       AC K9X8S8.1
#=GS A0A0A2LUX5_9FLAO/69-123   AC A0A0A2LUX5.1
#=GS D4K6W8_9FIRM/59-100       AC D4K6W8.1
#=GS A0A0K9JW04_9BURK/117-166  AC A0A0K9JW04.1
#=GS C4ZE47_AGARV/54-101       AC C4ZE47.1
#=GS U2L955_9BACT/72-115       AC U2L955.1
#=GS R9LZN4_9FIRM/57-101       AC R9LZN4.1
#=GS G9RVH7_9FIRM/59-104       AC G9RVH7.1
#=GS V2TF79_9GAMM/101-146      AC V2TF79.1
#=GS E1VTE9_GLUAR/101-144      AC E1VTE9.1
#=GS B9D640_CAMRE/16-58        AC B9D640.1
#=GS V2XRY1_9FIRM/60-100       AC V2XRY1.1
#=GS N2ATW4_9CLOT/17-69        AC N2ATW4.1
#=GS R5J1D4_9FIRM/26-70        AC R5J1D4.1
#=GS Q5HS44_STAEQ/82-131       AC Q5HS44.1
#=GS C4ZEP1_AGARV/59-110       AC C4ZEP1.1
#=GS Q5DY55_VIBF1/97-142       AC Q5DY55.1
#=GS E6K6H3_9BACT/72-115       AC E6K6H3.1
#=GS A0A0F5RBH4_9BACL/56-103   AC A0A0F5RBH4.1
#=GS C7HVB4_9FIRM/30-72        AC C7HVB4.1
#=GS R6TWK1_9FIRM/60-103       AC R6TWK1.1
#=GS A0A0J5Q8P5_9RHOB/114-167  AC A0A0J5Q8P5.1
#=GS R5MW63_9FIRM/56-98        AC R5MW63.1
#=GS R9JZP9_9FIRM/59-100       AC R9JZP9.1
#=GS G4D741_9FIRM/46-90        AC G4D741.1
#=GS I0TD97_9BACT/70-115       AC I0TD97.1
#=GS A5WI53_PSYWF/62-106       AC A5WI53.1
#=GS D2QW28_SPILD/53-93        AC D2QW28.1
#=GS E6K5C3_9BACT/72-115       AC E6K5C3.1
#=GS D1PJZ9_9FIRM/59-103       AC D1PJZ9.1
#=GS R9L7Q0_9FIRM/70-128       AC R9L7Q0.1
#=GS B9JPQ2_AGRRK/70-119       AC B9JPQ2.1
#=GS E2ZEU9_9FIRM/127-169      AC E2ZEU9.1
#=GS A0A0A0DE55_9STRE/49-99    AC A0A0A0DE55.1
#=GS R5A5Y5_9CLOT/57-101       AC R5A5Y5.1
#=GS A0A0D6E0Q0_9LACT/57-106   AC A0A0D6E0Q0.1
#=GS C2D1I4_LACBR/189-232      AC C2D1I4.1
#=GS A0A0D6NG76_9PROT/63-108   AC A0A0D6NG76.1
#=GS R8W1K3_9CLOT/59-103       AC R8W1K3.1
#=GS A0A159Z9L1_9RHOB/113-142  AC A0A159Z9L1.1
#=GS K9ZPA1_ANACC/59-109       AC K9ZPA1.1
#=GS A3U277_PSEBH/38-86        AC A3U277.1
#=GS U2DSS9_CLOS4/55-104       AC U2DSS9.1
#=GS C8S1P5_9RHOB/21-72        AC C8S1P5.1
#=GS W0EQT9_9PORP/73-113       AC W0EQT9.1
#=GS R5UEX1_9BACT/75-118       AC R5UEX1.1
#=GS A0A142HV17_9SPHI/66-109   AC A0A142HV17.1
#=GS A0A0N0SGJ3_9ACTN/188-234  AC A0A0N0SGJ3.1
#=GS R9IE36_9FIRM/61-113       AC R9IE36.1
#=GS F4X9W7_9FIRM/57-95        AC F4X9W7.1
#=GS D4JXS8_9FIRM/59-103       AC D4JXS8.1
#=GS C7HTK3_9FIRM/30-73        AC C7HTK3.1
#=GS R9LCU8_9FIRM/59-104       AC R9LCU8.1
#=GS A7ZGK0_CAMC1/56-97        AC A7ZGK0.1
#=GS R9K761_9FIRM/60-100       AC R9K761.1
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U2AJ48_9CLOT/59-113                  .........vsl---QRRCANNLNQVAVHAN..............MYG.V...Y.P..E....E...I.A....GL..Q...RDYETLWG-----qvsdvlkelselvak......................
D3AFZ0_9CLOT/59-111                  .........vsl---MRRSSNNLNQLTRKVH.............eTGR.V...Y.D..A....D...L.E....DI..S...QRQEQLWEGVEEIltqlskl..............................
J4KA96_9FIRM/57-104                  ...dlqgllsna-------TNNINQIAKRVN.............qTGI.I...Y.K..D....D...I.Q....DM..K...KKIEHFSKELWQI.....................................
W6TM11_9SPHI/75-116                  ............-NELSAIGSNLNQIARKIN..............-SY.V...T.T..P....S...L.K....LL..M...ESCRLVKESVD--t....................................
A0A081BL09_9LACO/63-104              ...........a---LARIGNNLNQLAKRAN.............aDNP.T...A.L..A....D...I.N....AL..R...SEVNQLWQQLR--.....................................
A6NU40_9FIRM/43-96                   .vvvidglkevl-KELKSIGRNLNQLVTLAH..............MGR.V...T.V..I....N...L.D....GV..R...QAFSEL-------caavrl...............................
R9MX05_9FIRM/60-103                  ...........t--ELGRISSSLNQIAKRIN.............sTNH.I...Y.Q..E....D...M.D....EV..K...ELMKQVWQS----qks..................................
A0A163UR38_9RHOB/50-100              ..........ta---LSRIGTNLNQIARAVNa............aQAA.G...D.M..R....Q...L.D....GL..Q...L------------laeligierqmaallas....................
A0A060RE17_9BACT/38-61               ...........i-TKLTGMANNLNQIAKRAN..............QA-.-...-.-..-....-...-.-....--..-...-------------gcr..................................
D9VJ95_9ACTN/96-141                  ............-RLLIGVATNVNQMAAVAN..............-ST.G...E.L..P....A...A.A....QL..E...GALALVQRQVER-igel.................................
E7RPP5_9BACT/72-115                  ............IRKLCGMANNLNQLAHRAN..............-AD.G...F.H..V....V...A.P....FH..K...IIIGKIDEILN--li...................................
K7RWF8_PROA4/79-123                  ...........f-RLLGTIANNVNQIARATN..............ATG.Q...I.Q..D....D...L.G....GT..L...EAVRRVGDRLDSL.....................................
B0P8S1_9FIRM/54-101                  ........taey----GRIGGNLNQIARTLNe...........whS--.-...P.-..-....-...-.-....--..-...-------------ypqlagevraavsdlaalkfevlq.............
E0E4C3_9FIRM/57-104                  ...dlqgllsna-------TNNINQIAKRIN.............sTGI.I...Y.K..E....D...I.S....DI..K...KEIEHFSKELWQI.....................................
C8Q002_9PROT/55-82                   ...........v-HQVARIGSNLNQIARHAN..............T--.-...-.-..-....-...-.-....--..-...-------------eknwmpvc.............................
U2L4S8_9FIRM/59-103                  ...........t-AELQKIGVNINQIARRTN.............tTGN.V...Y.P..E....D...I.E....EI..K...GALKEIWR-----lqrl.................................
B5GPI2_STRC2/159-202                 ...........t-AQLARAGNNLNQVARVLN..............SGG.H...S.D..A....V...-.-....--..-...-------------dqtvgrvqraavrveaa....................
A0A0U3HEH8_9MICC/80-115              ..........hl---MATIANNVNQIARHAN.............sTGE.V...L.P..E....T...V.E....TL..Q...EA-----------rr...................................
A0A0J5Q6V7_9RHOB/114-167             ..........aa---LNRVGNNVNQVARRLN..............EAK.-...-.-..-....-...-.-....--..-...-------------lrgeplpytaashaeirdlaglvfdmadqiqel....
A3VKV8_9RHOB/114-143                 ..........aa---LNRVGNNVNQIARRLN..............EAT.V...-.-..-....-...-.-....--..-...-------------rgerlsyp.............................
R6MF45_9FIRM/59-102                  ..........nk--ELHSIGVNINQIAKRVN.............eTGS.I...Y.E..E....D...I.K....EI..Q...ERLNKIWQ-----lqr..................................
R9MNG0_9FIRM/70-117                  ........taey----GKIGGNLNQIARCLN..............-EY.G...A.P..Y....N...-.-....--..-...-------------alsqevraataelaalkfevlq...............
A0A0H1A0P3_9MICC/76-120              ..........rg---LAAAGNNINQIARVAN..............TTG.E...I.K..D....E...L.H....DS..L...EHLRATVARIDE-vl...................................
A1VX77_POLNA/74-120                  ............LRQLVGMGNNLNQIAKLANi............aSKT.A...Q.P..M....A...M.V....EL..L...ITLKGIEKSLEKL.....................................
E0UNH0_CYAP2/58-106                  ...........l--KLGKISNNINQITKVLNth.........nkfNAN.V...P.Y..D....V...I.F....EL..K...EQLANVSTQIDQI.....................................
A0A0N0ASU7_9ACTN/79-126              ...........t--ELTRIGTNVNQIAHRYNag..........gdAHP.V...D.A..T....V...L.A....EA..R...RLVAV--------vkqtitav.............................
E8LH26_9FIRM/59-103                  .......llric-------SNNLNQYAKRAN.............eTGS.I...Y.R..A....D...I.E....DL..Q...KRLEEIWTDMR--evl..................................
C5ETF0_9FIRM/60-104                  ...........t-NEINHIGININQIVKNNN..............SGL.Y...H.E..S....D...K.K....RL..Y...VYMKQIKEAVM--qv...................................
A0A0K2RV32_9MICC/53-82               ..........nl---LARSSNNINQLARHAN..............ATS.E...F.P..A....E...A.A....R-..-...-------------h....................................
A0A0C5L1M1_9SPHN/68-113              ..........gq----SRIANNLNQLARQANlg.........tlpV--.-...-.-..-....-...-.-....--..-...-------------tpdteaalaeaaadiaamramlv..............
A0A0B4XBJ7_9RHIZ/75-123              ...........i-SDMRSVGVNLNQLARSAN.............aSGR.L...S.D..A....D...L.AlelrEV..Q...RLVAAV-------vlelrs...............................
A0A0B2ALJ3_9MICC/53-96               ..........tl---LGAVSNNVNQIARHAN..............ATG.E...F.P..D....D...A.A....AA..V...AVARRLMARIDE-a....................................
N2AI72_9FIRM/59-104                  .........lsl---LRRTSNNINQVARRVH.............eTGN.I...Y.D..T....D...L.E....DI..L...QKQKELWDGVNEI.....................................
R6PFF9_9CLOT/69-107                  ........vsey----GKIGSNLNQIARYFN.............sGGD.R...-.-..-....-...-.-....--..-...-------------sraveeeihqcisal......................
T5S2I8_9FIRM/59-103                  ...........a-AEINKIGVNINTVCRRIN.............sTGR.F...Y.Q..D....D...I.D....EL..K...EKMDAVWQLLK--l....................................
E8LDJ1_9FIRM/183-217                 ........taey----GRIGGNLNQIARYLN..............EYG.-...-.-..-....-...-.-....--..-...-------------vpyntlsgevraa........................
F7KHA5_9FIRM/59-104                  .........vsl---MRRSSNNLNQLTRKVH.............eTGR.V...Y.D..A....D...L.E....DI..S...QRQEQLWEGVKEI.....................................
A0A133QD17_9BACT/70-114              ............IRTVSGLANNLNQIAHRLNa............fGIS.A...L.N..E....E...L.N....AL..K...QLIHELMKRLK--.....................................
N2A3R2_9CLOT/71-120                  ........taey----GRIGGNLNQIARCLN.............eYGA.L...Y.N..A....-...-.-....--..-...-------------lsgevraaisdlaalkfevlqkv..............
C0EF97_9FIRM/50-94                   ..........tt--ELSAIGRNINQIAKQIN.............aTGS.S...Y.Q..A....D...M.E....EI..R...ERLDEIWQ-----lqrh.................................
A0A0H0ZVG7_9MICC/76-123              ..........rg---LAAAGNNINQIARAANat..........geIQG.E...L.H..D....S...L.D....HL..R...ATVKRIDDVL---etl..................................
R6EN78_9FIRM/66-109                  ............-FQIRKIGVNINQATKKIN..............SGY.Y...D.R..K....I...C.E....DL..Q...NSLEELNRHFQEL.....................................
A0A159ZAZ9_9RHOB/114-142             ..........aa---LNRVGNNVNQIARRLN..............EAK.V...-.-..-....-...-.-....--..-...-------------rgerlsy..............................
R6FJB1_9BACE/64-119                  ............-NELSHIGGNLNQSVKRANelsvag..llppeyLRE.V...L.M..P....V...I.R....ET..Q...DTLNEIKRELEE-v....................................
C2BGI0_9FIRM/57-81                   .......emstn---ISHTSNNINQIAKRVN..............TT-.-...-.-..-....-...-.-....--..-...-------------si...................................
A0A010STS6_PSEFL/49-85               ...........s--ELARAAANLNQIARQLN..............-ID.S...D.P..F....D...F.D....QL..R...KEL----------hafr.................................
D4BSD3_BIFBR/70-115                  ...........a-REIDRIGVNVNQIAHWAN.............aNEH.I...T.P..A....Q...V.E....EI..R...ASFDRIERLL---gdl..................................
E9SEI2_RUMAL/59-104                  .........lng---MRIISNNINQVARKAN.............eTNS.I...Y.A..E....D...V.E....KL..R...KEVEALSHTLS--kf...................................
A0A024HL18_PSEKB/55-98               ............INELSRIGNNLNQLARHAN.............sGSS.I...T.P..N....D...L.A....RI..W...HSLELLWAA----fq...................................
A0A069D1W8_9LACT/65-107              ...........s--QVNRIGNNVNQVAKLAH.............lFNE.I...S.P..A....E...I.E....EL..K...GMLQEMKQLI---t....................................
I4Z9Y3_9BACT/70-114                  ............IRTVSGMANNLNQIAHRLNa............fGIS.A...L.N..E....D...L.N....AL..K...QLINELMKRLK--.....................................
R5F0D6_9CLOT/59-103                  ............INEVNRIGININQIVFNNN..............AGL.Y...S.K..E....D...K.T....QL..I...AYMRKLNQKIDE-a....................................
J4TBC8_9FIRM/65-104                  ..........at--------NNINQIAKHVN.............sTGI.I...Y.R..D....D...I.N....DM..K...KQIEHFSKELWQI.....................................
C7H1E4_9FIRM/59-103                  ...........t-AEIQKIGVNVNQIAKRVN.............aTGS.V...Y.Q..E....D...I.E....EI..K...EVLAEIWR-----lqrl.................................
A0A125P3L2_9BURK/69-115              ..........lf----NKTSNNMNQLAHAANaa..........elAGT.A...T.P..A....T...Y.A....GI..L...AELQAIADAMR--ea...................................
R9KNA7_9FIRM/61-100                  ...........t---LGKISGNLNQIAKRMN.............aTGN.V...Y.K..A....D...V.E....EV..K...KLMKQVWD-----t....................................
K0YVK8_9ACTO/89-136                  ............-RKLTGLANNLNQLTRYAHvk..........geLPQ.H...I.D..D....V...L.G....QV..E...RSVDEINYLLA--sv...................................
H1YF60_9SPHI/73-129                  .........irk--ELKAIGININQITRHFNad.........kveTHK.G...F.Y..A....-...-.-....--..-...-------------lkvadqykkvderveillkiiskla............
F4FI57_VERMA/63-107                  ...........h-RQVRGAATNLNQAVARLH..............ATG.E...P.A..G....D...L.A....AS..A...AYVARIAARVDEL.....................................
D4K2I8_9FIRM/59-104                  .........vsl---MRRSSNNLNQLTRKVH.............eTGR.V...Y.D..A....D...L.E....DI..S...QRQEQLWEGVKEI.....................................
R9M5Q2_9FIRM/59-100                  ...........t-AEIQKIGVNVNQIARRVN.............sTGT.V...Y.A..Q....D...M.E....DI..K...GALAEIWR-----l....................................
R9IPW3_9FIRM/70-115                  ........taey----GKIGGNLNQIARCLN.............eYGA.P...Y.N..A....L...S.K....EV..Q...AAIAELA------alkfev...............................
A0A0D6WWA8_9ACTN/70-119              ...........g--QLAKIGNNLNQLTRHLNqda........pwpAPD.L...V.R..E....L...L.R....HV..E...ASIADVDTAV---aqv..................................
A0A0K9X8N1_9ACTN/156-201             ...........a--EVARIGNNVNQIAHRLNag..........gdPHS.V...D.T..A....V...L.T....QT..E...RTLDTVRAA----ig...................................
U2SAX3_9FIRM/59-102                  ............IRELQAVSRNINQIAKRAN.............aTGT.V...Y.R..Q....D...I.E....DI..K...KAVDEIWR-----lqr..................................
A0A0F5R9H8_9BACL/56-103              ............MRELHAIGNNLNQLAAKAHat.........ghlDRA.S...F.Q..Q....E...A.D....HL..R...RAVQQIQQ-----avt..................................
G5KG22_9STRE/61-106                  ...........v-FELRRIGNNINQIARAIN.............qSHL.I...S.Q..E....Q...L.Q....DL..S...KGVGELIKEVDK-e....................................
A0A095Y019_9BACT/67-120              ...........h--EISKQGVNLNQITKRANel..........iyK--.-...-.-..-....-...-.-....--..-...-------------galdkeyydeiilphvsdlkkmmatmkkqqs......
G2GYD8_9ENTR/135-175                 ............-RELAAIGRNLNQIARTLN..............---.V...E.F..R....D...S.D....KL..N...KEL----------idrlleqidg...........................
A0A0L1KNS0_9BURK/71-115              ..........fn-----KTSNNLNQIAHRANse..........hvSGK.L...S.E..A....T...Y.E....QL..L...TQLQMIGQYL---ra...................................
R6PVU6_9CLOT/59-104                  ............LEEMRRIGTNMNQIARQANsi.........gfiD--.-...-.-..-....-...T.-....--..-...-------------naywenvkaledaisdikke.................
C7H1R1_9FIRM/84-123                  ..........sa--QCSKVGSNLNQLARHFN..............SGG.K...D.T..E....Q...LrA....QI..L...EEL----------salt.................................
A0A0D6JKC4_9RHIZ/74-117              ...........v-HQLARIGNNLNQLAHQAN..............-IG.Y...V.A..V....P...M.Q....EI..R...SCIDAINQKVAQL.....................................
R6B344_9CLOT/57-99                   .....stidhlc--------INVNQIAHHAN.............mQGG.I...T.A..E....E...A.A....EA..K...RLVMEIRKRL---y....................................
R9LLD5_9FIRM/53-104                  ...rdikemnkl---LSAIGRNINQIAKRVN.............aRGS.T...Y.Q..A....D...M.E....EI..R...ERLDQIWQ-----lqrri................................
R9L640_9FIRM/32-78                   .....vslmrys-------SNNLNQLTRKVH.............eTGR.V...Y.D..A....D...L.E....DI..S...QRQEQLWDGVQKIl....................................
A0A136Q609_9FIRM/56-94               ............MRELSSIGNNINQLAAKAN..............--T.L...G.F..I....D...A.P....ML..K...NEAAK--------wnkf.................................
E2ZJ21_9FIRM/60-103                  .......llqnc-------SNNLNQVAKRVN.............eSGK.I...Y.A..A....D...L.A....DL..R...TRLDELID-----igkqi................................
R9N3B1_9FIRM/70-118                  ........taey----GKIGGNLNQIARCLNey..........gaP--.-...Y.N..A....L...S.Q....EV..Q...AATAEL-------aalkfevlqk...........................
R9IIA0_9FIRM/54-106                  ....msdiqemi-RLLRICSNNLNQYARRAN.............eTGS.V...Y.S..A....D...V.D....DL..R...TRLDSLWDGMDKL.....................................
U2CPW8_9CLOT/55-101                  ..........ip--ELKRIGNNLNQIAKRCNe............gGML.P...S.E..A....E...V.R....KH..G...EELNKVWQSLRR-y....................................
A0A060RAH8_9BACT/73-118              ...........i-TKLTGMANNLNQIAKRAN..............QAG.Y...F.A..Ak..tE...S.E....TL..A...KEIDNVIKSIE--n....................................
A0A0Q8Q018_9SPHN/120-158             ...........w-RELNRIGINLNQATRALN..............-AS.-...-.-..-....-...-.-....--..-...-------------vmvesgldvareaarvas...................
A0A087CL65_9BIFI/96-137              ..........at--QIAKVGTNINQIARVAN.............sQGV.V...L.D..R....Q...V.L....RL..V...EQMRPL-------lrd..................................
R9LD40_9FIRM/61-113                  .....vslmrys-------SNNLNQLTRKVH.............eTGR.V...Y.D..A....D...L.E....DI..S...QRQEQLWEGVQKIlaqlskl..............................
D3AQJ5_9CLOT/64-99                   ..........iy--EVNRIGNNVNQIAYNTN.............aVRF.S...S.N..K....D...W.G....EL..-...-------------qtky.................................
R9IG64_9FIRM/59-100                  ...........t-AELQKIGVNVNQIAKRIN.............sTGT.V...Y.A..Q....D...V.E....DI..K...GALAEIWQ-----l....................................
N2A7C2_9CLOT/59-103                  ...........t-AEIQKIGVNVNQIARRVN.............aTGN.A...Y.Q..E....D...I.E....EI..K...GVLAEIWR-----lqrl.................................
K6T613_9CLOT/54-98                   ...........t-HQLSKIGTNLNQLTRLCH..............QGK.I...N.C..A....D...I.T....SV..N...KLLNDLWEYL---vsi..................................
R9BA19_9GAMM/82-129                  ..........il--ELGRIGNNVNQIAKAINt............dIAG.T...G.T..F....D...K.V....KL..L...HLLISIDQQLRELr....................................
R9LKL1_9FIRM/74-128                  ............----GKIGGNLNQIARCLN..............-EY.G...A.-..-....-...-.-....--..-...-------------pyntlsnevraalselaalkfevlqkvgeavgniqt.
B0PDJ2_9FIRM/59-103                  ...........t-AEIQKIGVNVNQIARRVN.............aTGN.A...Y.Q..E....D...I.E....EI..K...GVLAEIWR-----lqrl.................................
A0A159ZAW6_9RHOB/75-121              .........lgh---LGKIGGNLNQIARYLH..............TGG.S...T.E..V....V...L.G....D-..-...-------------irdvladharirdrlye....................
V2YAT2_9FIRM/56-101                  ............LRELSAIGNNVNQIAYWAN.............aTKG.I...G.K..A....E...I.A....EA..A...ALVRQAWRMV---ket..................................
A0A073IBW2_9RHOB/75-120              ..........rv---IRTIANNVNQMARHSN.............rI--.A...H.V..L....D...E.Q....EV..F...LNIHALQSELKQ-aisr.................................
M2NET2_9FIRM/57-104                  ...dlqgllsna-------TNNINQIAKRVN.............sTGV.I...Y.K..E....D...I.G....DI..K...KEIEHFSKELWQI.....................................
F5J133_9PORP/71-112                  ............MRKLAGMANNLNQVAKRVN..............-RN.E...F.L..Q....V...G.L....DL..V...ILAGKI-------kelvd................................
D7GTX6_9FIRM/59-104                  ...........m-AQLQKIGGNLNQITKRIN.............eTER.I...Y.D..N....D...M.D....EL..K...RLMDEVWKL----erql.................................
R8W0G8_9CLOT/72-112                  ..........va--QYGKIGSNLNQIARYLN..............-EY.G...A.P..-....-...-.-....--..-...-------------ynalsgevrtavsdlaa....................
R6H6W2_9FIRM/60-105                  .........vsl---QRRCSNNLNQVAIQAN.............tYGG.I...Y.P..E....E...I.A....AL..Q...RDYAALW------gplsdl...............................
A0A132BTH1_9RHOB/66-104              .......gqtrh-------ANNLNQIAKAINq............gTLY.V...D.D..E....L...A.A....DI..Q...AALADI-------a....................................
R5QCK1_9FIRM/56-100                  ...........a-HELQRIGNNLNQLTRAVN..............AGF.V...R.V..V....D...L.G....ET..K...QEVQKVWQSLNSL.....................................
K9AUH1_9STAP/78-122                  ..........ak--DLSMLGANANQIAKYCN..............QHQ.Y...E.A..P....D...Y.E....AL..E...RNIKIVRERLDEI.....................................
A0A133ZI69_9BACL/61-103              .......llsna-------TNNINQIAKATN.............tTGV.I...C.K..K....D...I.D....YM..R...EKIEKLSREI---wd...................................
U2KCJ0_9FIRM/186-231                 .........ary---ISSISNSFNQVAHRVN.............kGGK.L...Y.D..E....D...I.A....DM..K...ERLEEIWRLL---vsi..................................
N2AFN9_9CLOT/56-101                  ............LRKIAGLCNNANQLAHVAN.............aSGS.A...S.P..E....S...L.R....EM..L...QISRETWQLVKE-e....................................
F7UX80_EEGSY/56-104                  ...........a-RELHAIGSNLNQIARKAH..............--V.L...N.V..V....D...A.A....RY..D...AEARKLEAALAEIaaavke...............................
A5FDM0_FLAJ1/70-120                  ...........t-SELRAIGNNINQIARKINtlktv....pefkgHLY.L...F.E..I....Q...R.E....RL..F...DKME---------evsvh................................
K6VB62_9ACTN/84-126                  ..........nl---LSGLAVNMNQIARHAN..............TEG.E...I.P..A....D...F.A....AA..V...LAARRASER----vrd..................................
C0EI84_9FIRM/59-107                  .........vsl---QRRCSNNINQVAIHAN..............TYG.V...Y.P..D....E...I.A....GL..Q...QDYAELWGRMN--dilkql...............................
R9N371_9FIRM/70-117                  ........taey----GKIGGNLNQIARCLN..............-EY.G...A.P..Y....N...-.-....--..-...-------------alsqevraataelaalkfevlq...............
F9PAS2_STRCV/63-107                  ...........t--EINRIGTNVNQLAKYVN.............tNEV.V...S.L..E....N...F.Q....TI..Q...TALTEVKRLMD--en...................................
E6K208_PARDN/79-117                  ...........a--EIHRIGVNINQIAHRVN.............mGGK.V...D.I..P....T...I.E....RL..L...EK-----------adsli................................
N1MK75_9SPHN/116-154                 ..........qa---LQRIGRNVNQIARAAN..............-KM.A...L.A..D....N...A.A....EI..A...GELQKVND-----l....................................
N2A4X1_9FIRM/59-103                  ............INEVNAIGNNINQITRNYN..............SKL.Y...R.M..E....D...R.E....LL..C...ACMKKLNMTV---rea..................................
R5TRI3_9FIRM/36-86                   ..........vy--QFRKIGTNINQATKQLH..............IGY.E...P.A..A....A...A.D....RL..E...KNMKLLEQQFEK-mkeelkq..............................
#=GC seq_cons                        ...........h...ltplGsNlNQIA+phN..............sst.h...h.t..t....p...h.t....ph......t.htth.......h....................................
//
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