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Database: Pfam
Entry: MobC
LinkDB: MobC
Original site: MobC 
#=GF ID   MobC
#=GF AC   PF05713.9
#=GF DE   Bacterial mobilisation protein (MobC)
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_2832 (release 8.0)
#=GF GA   22.00 22.00;
#=GF TC   22.00 22.00;
#=GF NC   21.90 21.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11976306
#=GF RT   Characterization of two cryptic Helicobacter pylori plasmids: a
#=GF RT   putative source for horizontal gene transfer and gene shuffling. 
#=GF RA   Hofreuter D, Haas R; 
#=GF RL   J Bacteriol 2002;184:2755-2766.
#=GF RN   [2]
#=GF RM   9302013
#=GF RT   The relaxosome protein MobC promotes conjugal plasmid
#=GF RT   mobilization by extending DNA strand separation to the nick site
#=GF RT   at the origin of transfer. 
#=GF RA   Zhang S, Meyer R; 
#=GF RL   Mol Microbiol 1997;25:509-516.
#=GF DR   INTERPRO; IPR008687;
#=GF CC   This family consists of several bacterial MobC-like,
#=GF CC   mobilisation proteins. MobC proteins belong to the group of
#=GF CC   relaxases. Together with MobA and MobB they bind to a single
#=GF CC   cis-active site of a mobilising plasmid, the origin of transfer
#=GF CC   (oriT) region [1]. The absence of MobC has several different
#=GF CC   effects on oriT DNA. Site- and strand-specific nicking by MobA
#=GF CC   protein is severely reduced, accounting for the lower frequency
#=GF CC   of mobilisation. The localised DNA strand separation required
#=GF CC   for this nicking is less affected, but becomes more sensitive to
#=GF CC   the level of active DNA gyrase in the cell. In addition, strand
#=GF CC   separation is not efficiently extended through the region
#=GF CC   containing the nick site. These effects suggest a model in which
#=GF CC   MobC acts as a molecular wedge for the relaxosome-induced
#=GF CC   melting of oriT DNA. The effect of MobC on strand separation may
#=GF CC   be partially complemented by the helical distortion induced by
#=GF CC   supercoiling. However, MobC extends the melted region through
#=GF CC   the nick site, thus providing the single-stranded substrate
#=GF CC   required for cleavage by MobA [2].
#=GF SQ   872
#=GS G4Q4L7_ACIIR/71-118       AC G4Q4L7.1
#=GS H1PNI9_9FIRM/55-101       AC H1PNI9.1
#=GS U2RCS5_9FIRM/46-90        AC U2RCS5.1
#=GS I1YRZ2_PREI7/70-114       AC I1YRZ2.1
#=GS A4CGM8_ROBBH/66-108       AC A4CGM8.1
#=GS G8TJG2_NIAKG/68-112       AC G8TJG2.1
#=GS C7H3N1_9FIRM/60-103       AC C7H3N1.1
#=GS D4JED5_9FIRM/61-113       AC D4JED5.1
#=GS D4K1U1_9FIRM/83-121       AC D4K1U1.1
#=GS W0ES94_9PORP/73-113       AC W0ES94.1
#=GS E2CS57_9RHOB/85-134       AC E2CS57.1
#=GS V6KKV9_STRRC/130-174      AC V6KKV9.1
#=GS C7PJH0_CHIPD/68-123       AC C7PJH0.1
#=GS F3ZAN4_9ACTN/93-140       AC F3ZAN4.1
#=GS E2ZN32_9FIRM/54-96        AC E2ZN32.1
#=GS F7KH57_9FIRM/64-99        AC F7KH57.1
#=GS R6WAY1_9FIRM/73-115       AC R6WAY1.1
#=GS K1LPG9_9LACT/61-104       AC K1LPG9.1
#=GS G4KS41_OSCVS/52-96        AC G4KS41.1
#=GS V4SPA9_STRIN/65-106       AC V4SPA9.1
#=GS R5NTS2_9CLOT/51-91        AC R5NTS2.1
#=GS D4IKK1_9BACT/72-115       AC D4IKK1.1
#=GS D6GPN1_FILAD/57-104       AC D6GPN1.1
#=GS B2JC06_NOSP7/81-136       AC B2JC06.1
#=GS D4M3I9_9FIRM/54-103       AC D4M3I9.1
#=GS A1RDC9_ARTAT/144-187      AC A1RDC9.1
#=GS A0A0N0TNX8_9ACTN/40-81    AC A0A0N0TNX8.1
#=GS E7RM52_9BACT/121-164      AC E7RM52.1
#=GS R6WPI6_9BACT/70-113       AC R6WPI6.1
#=GS B8HJI3_ARTCA/53-96        AC B8HJI3.1
#=GS G6XJ17_9PROT/54-95        AC G6XJ17.1
#=GS F5J1X4_9PORP/73-114       AC F5J1X4.1
#=GS B7K6N2_CYAP8/67-94        AC B7K6N2.1
#=GS R7N4C7_9FIRM/63-108       AC R7N4C7.1
#=GS A0A0B4S1S6_9FIRM/68-109   AC A0A0B4S1S6.1
#=GS C4ZFK0_AGARV/60-103       AC C4ZFK0.1
#=GS G0HF26_CORVD/79-124       AC G0HF26.1
#=GS C6RGU8_9PROT/2-46         AC C6RGU8.1
#=GS D4M204_9FIRM/71-120       AC D4M204.1
#=GS E3I6L8_RHOVT/78-125       AC E3I6L8.1
#=GS R7JFG9_9PORP/72-115       AC R7JFG9.1
#=GS B9D154_CAMRE/61-113       AC B9D154.1
#=GS A5VGY8_SPHWW/112-160      AC A5VGY8.1
#=GS H1Y1U3_9SPHI/70-97        AC H1Y1U3.1
#=GS C4GE66_9FIRM/57-104       AC C4GE66.1
#=GS A0A0J7ZG71_STRVR/158-200  AC A0A0J7ZG71.1
#=GS R6PGU8_9CLOT/69-106       AC R6PGU8.1
#=GS E9S781_RUMAL/52-95        AC E9S781.1
#=GS A6X801_OCHA4/99-148       AC A6X801.1
#=GS A0A0F5P7S0_9SPHN/114-156  AC A0A0F5P7S0.1
#=GS G2H041_9ENTR/63-107       AC G2H041.1
#=GS C7H2R6_9FIRM/58-98        AC C7H2R6.1
#=GS E3GPA0_EUBLK/78-136       AC E3GPA0.1
#=GS S6CB96_9ACTN/56-104       AC S6CB96.1
#=GS R6TNL5_9CLOT/54-98        AC R6TNL5.1
#=GS Q9KYB4_STRCO/121-163      AC Q9KYB4.1
#=GS R7AEW4_9CLOT/57-102       AC R7AEW4.1
#=GS B2JC20_NOSP7/81-136       AC B2JC20.1
#=GS F4XGI1_9FIRM/59-112       AC F4XGI1.1
#=GS A0A0M2NHG0_9FIRM/60-103   AC A0A0M2NHG0.1
#=GS E1VRH1_ARTAR/83-126       AC E1VRH1.1
#=GS A3DKF2_CLOTH/53-92        AC A3DKF2.1
#=GS I3YQU9_ALIFI/75-103       AC I3YQU9.1
#=GS J5H5I6_9FIRM/180-227      AC J5H5I6.1
#=GS A0A0F2JIY4_9FIRM/12-57    AC A0A0F2JIY4.1
#=GS G2IU41_9SPHN/120-158      AC G2IU41.1
#=GS D4H4Q4_DENA2/88-124       AC D4H4Q4.1
#=GS E0NMM2_9FIRM/61-104       AC E0NMM2.1
#=GS A0A0B7H3E8_9FLAO/89-134   AC A0A0B7H3E8.1
#=GS D4L2K1_9FIRM/53-108       AC D4L2K1.1
#=GS A6AS96_VIBCY/69-104       AC A6AS96.1
#=GS I3UHY5_ADVKW/14-60        AC I3UHY5.1
#=GS E2ZFR5_9FIRM/59-100       AC E2ZFR5.1
#=GS R4KC44_9FIRM/56-82        AC R4KC44.1
#=GS A6X7N5_OCHA4/99-148       AC A6X7N5.1
#=GS J5UQ82_9FIRM/61-104       AC J5UQ82.1
#=GS R5QE94_9FIRM/59-103       AC R5QE94.1
#=GS D6DD45_BIFLN/75-122       AC D6DD45.1
#=GS A5VH27_SPHWW/65-114       AC A5VH27.1
#=GS C7H8P9_9FIRM/59-103       AC C7H8P9.1
#=GS G2G6K2_9ACTN/117-164      AC G2G6K2.1
#=GS R2PSI2_9ENTE/88-133       AC R2PSI2.1
#=GS D4K4J5_9FIRM/71-120       AC D4K4J5.1
#=GS G4HIK3_9BACL/36-84        AC G4HIK3.1
#=GS Q0FUC9_PELBH/106-134      AC Q0FUC9.1
#=GS R6PVU6_9CLOT/59-106       AC R6PVU6.1
#=GS A0A0M9E7H0_9DELT/67-111   AC A0A0M9E7H0.1
#=GS C6LDB3_9FIRM/54-106       AC C6LDB3.1
#=GS D3LWZ1_9FIRM/57-104       AC D3LWZ1.1
#=GS R6PPQ0_9CLOT/79-124       AC R6PPQ0.1
#=GS G9RUS8_9FIRM/59-112       AC G9RUS8.1
#=GS Q8A8P0_BACTN/140-179      AC Q8A8P0.1
#=GS A0A015NI74_9GLOM/126-160  AC A0A015NI74.1
#=GS I4EB25_METSZ/109-159      AC I4EB25.1
#=GS W6RPZ4_9RHIZ/75-123       AC W6RPZ4.1
#=GS K9UE41_9CHRO/75-131       AC K9UE41.1
#=GS A0A0F4LL71_9LACO/58-106   AC A0A0F4LL71.1
#=GS F8ER75_RUNSL/70-113       AC F8ER75.1
#=GS A0A0M2NGP9_9FIRM/56-95    AC A0A0M2NGP9.1
#=GS D4MPJ5_9FIRM/57-102       AC D4MPJ5.1
#=GS G9YS23_9FIRM/69-105       AC G9YS23.1
#=GS D4IJW2_9BACT/75-118       AC D4IJW2.1
#=GS R5CBX4_9BACE/75-114       AC R5CBX4.1
#=GS E5YA73_BILWA/58-101       AC E5YA73.1
#=GS D3Q2W1_STANL/80-123       AC D3Q2W1.1
#=GS A3JLT9_9RHOB/71-116       AC A3JLT9.1
#=GS E2ZJD6_9FIRM/83-121       AC E2ZJD6.1
#=GS R5MW63_9FIRM/56-97        AC R5MW63.1
#=GS D4K3L7_9FIRM/71-107       AC D4K3L7.1
#=GS Q8E0T1_STRA5/24-53        AC Q8E0T1.1
#=GS D2ZSZ9_NEIMU/113-156      AC D2ZSZ9.1
#=GS B9YBU1_9FIRM/80-122       AC B9YBU1.1
#=GS I3U5U5_ENTFC/108-154      AC I3U5U5.1
#=GS C7HT63_9FIRM/61-104       AC C7HT63.1
#=GS D4M3M4_9FIRM/60-103       AC D4M3M4.1
#=GS R7FEA0_9FIRM/59-103       AC R7FEA0.1
#=GS B0S1X0_FINM2/61-104       AC B0S1X0.1
#=GS D5X3W4_THIK1/80-123       AC D5X3W4.1
#=GS A0AWK1_ARTS2/81-124       AC A0AWK1.1
#=GS A7HZD0_CAMHC/57-98        AC A7HZD0.1
#=GS G2T4N5_ROSHA/183-225      AC G2T4N5.1
#=GS A3X3Y8_9RHOB/76-112       AC A3X3Y8.1
#=GS H1YHU1_9SPHI/73-102       AC H1YHU1.1
#=GS A5N4V0_CLOK5/61-111       AC A5N4V0.1
#=GS D4W978_9FIRM/62-107       AC D4W978.1
#=GS G5GJE0_9FIRM/59-104       AC G5GJE0.1
#=GS B3JGV0_9BACE/76-120       AC B3JGV0.1
#=GS H8XSU6_FLAIG/65-106       AC H8XSU6.1
#=GS E6UDU4_RUMA7/114-157      AC E6UDU4.1
#=GS A0A077EIR1_9FLAO/64-102   AC A0A077EIR1.1
#=GS G5K777_9STRE/61-104       AC G5K777.1
#=GS F0H2Q2_9FIRM/61-104       AC F0H2Q2.1
#=GS G9RQP0_9FIRM/56-100       AC G9RQP0.1
#=GS E7GU94_CLOSY/59-100       AC E7GU94.1
#=GS A0A059W9L2_STRA9/147-195  AC A0A059W9L2.1
#=GS A0A060R9M9_9BACT/81-124   AC A0A060R9M9.1
#=GS E1KQQ1_9BACT/72-115       AC E1KQQ1.1
#=GS K7SCY2_GLUOY/54-95        AC K7SCY2.1
#=GS E4KYU6_9FIRM/60-103       AC E4KYU6.1
#=GS D6DF81_CLOSC/56-94        AC D6DF81.1
#=GS A3X864_9RHOB/38-86        AC A3X864.1
#=GS J6HFF6_9FIRM/60-101       AC J6HFF6.1
#=GS V6K575_STRRC/130-176      AC V6K575.1
#=GS L8EZ86_STRRM/115-157      AC L8EZ86.1
#=GS V5SH98_9RHIZ/49-76        AC V5SH98.1
#=GS H0I178_9RHIZ/55-97        AC H0I178.1
#=GS Q4JTW0_CORJK/70-110       AC Q4JTW0.1
#=GS J2JXM2_9ACTN/80-129       AC J2JXM2.1
#=GS D4LS38_9FIRM/59-103       AC D4LS38.1
#=GS G9YUC3_9FIRM/76-120       AC G9YUC3.1
#=GS A0A0N1GT52_9ACTN/215-261  AC A0A0N1GT52.1
#=GS A0A0N0ASU7_9ACTN/79-129   AC A0A0N0ASU7.1
#=GS R5EM74_9FIRM/2-39         AC R5EM74.1
#=GS H1YHD1_9SPHI/75-131       AC H1YHD1.1
#=GS E4KXX2_9FIRM/61-104       AC E4KXX2.1
#=GS J6HH40_9FIRM/59-103       AC J6HH40.1
#=GS F8X3R0_9PORP/74-119       AC F8X3R0.1
#=GS A0A060RCZ0_9BACT/54-99    AC A0A060RCZ0.1
#=GS N2BYV9_9ACTN/59-100       AC N2BYV9.1
#=GS C7H9F1_9FIRM/59-100       AC C7H9F1.1
#=GS C4Z3W3_EUBE2/66-111       AC C4Z3W3.1
#=GS D6DIX4_CLOSC/59-103       AC D6DIX4.1
#=GS V6KAU0_STRRC/130-175      AC V6KAU0.1
#=GS Q8CYS9_STRR6/61-106       AC Q8CYS9.1
#=GS C7RGW1_ANAPD/61-104       AC C7RGW1.1
#=GS D4KYE9_9FIRM/59-103       AC D4KYE9.1
#=GS B9YBX5_9FIRM/65-110       AC B9YBX5.1
#=GS D4L0I1_9FIRM/66-107       AC D4L0I1.1
#=GS C0MCH8_STRS7/60-104       AC C0MCH8.1
#=GS C7HVA5_9FIRM/32-74        AC C7HVA5.1
#=GS R5KCK6_9CLOT/59-103       AC R5KCK6.1
#=GS R6RGE7_9FIRM/48-92        AC R6RGE7.1
#=GS Q188L6_PEPD6/57-104       AC Q188L6.1
#=GS Q07GJ2_ROSDO/71-124       AC Q07GJ2.1
#=GS R6LLG8_9FIRM/53-97        AC R6LLG8.1
#=GS H3NR56_9FIRM/61-104       AC H3NR56.1
#=GS A6LE49_PARD8/75-105       AC A6LE49.1
#=GS G3Z1I0_9NEIS/123-161      AC G3Z1I0.1
#=GS G4KUJ3_OSCVS/61-109       AC G4KUJ3.1
#=GS A0A0B2AIB8_9ACTN/19-66    AC A0A0B2AIB8.1
#=GS R5E9P9_9CLOT/57-102       AC R5E9P9.1
#=GS Q0AM78_MARMM/66-108       AC Q0AM78.1
#=GS B4RFV6_PHEZH/112-156      AC B4RFV6.1
#=GS R6FQP6_9BACE/67-110       AC R6FQP6.1
#=GS D1VV32_9FIRM/61-104       AC D1VV32.1
#=GS F0H3D1_9FIRM/61-104       AC F0H3D1.1
#=GS D9SPS7_CLOC7/54-98        AC D9SPS7.1
#=GS A0A0D4CI48_9LACO/114-144  AC A0A0D4CI48.1
#=GS C2BGL4_9FIRM/61-90        AC C2BGL4.1
#=GS R7CXW1_9BACE/72-115       AC R7CXW1.1
#=GS R5S133_9FIRM/60-105       AC R5S133.1
#=GS J1JZ14_9RHIZ/62-107       AC J1JZ14.1
#=GS R5C6L6_9FIRM/57-103       AC R5C6L6.1
#=GS G9RNZ3_9FIRM/59-111       AC G9RNZ3.1
#=GS H8E8J6_9MICO/82-125       AC H8E8J6.1
#=GS C2BEP4_9FIRM/82-125       AC C2BEP4.1
#=GS D4MPI3_9FIRM/71-120       AC D4MPI3.1
#=GS Q7MVZ9_PORGI/72-115       AC Q7MVZ9.1
#=GS U7G6T7_9RHOB/50-91        AC U7G6T7.1
#=GS J9SKB5_9ACTN/84-124       AC J9SKB5.1
#=GS A0A0B5EY66_STRA4/40-91    AC A0A0B5EY66.1
#=GS G4KY18_OSCVS/77-121       AC G4KY18.1
#=GS R7L2F3_9FIRM/60-98        AC R7L2F3.1
#=GS F7V1W5_CLOSS/65-115       AC F7V1W5.1
#=GS B2VAX5_ERWT9/61-107       AC B2VAX5.1
#=GS E9SGK6_RUMAL/64-103       AC E9SGK6.1
#=GS I2N385_9ACTN/112-165      AC I2N385.1
#=GS F3ZL55_9ACTN/160-207      AC F3ZL55.1
#=GS K9X6L0_9NOST/82-138       AC K9X6L0.1
#=GS A0A0A2FLI6_9PORP/72-117   AC A0A0A2FLI6.1
#=GS K9X871_9NOST/82-131       AC K9X871.1
#=GS H1HPN8_9BACT/70-114       AC H1HPN8.1
#=GS G9RSK5_9FIRM/59-103       AC G9RSK5.1
#=GS A0A089LR14_9BACL/56-103   AC A0A089LR14.1
#=GS R5L325_9CLOT/34-77        AC R5L325.1
#=GS F4XHP8_9FIRM/59-103       AC F4XHP8.2
#=GS F7K6S6_9FIRM/59-104       AC F7K6S6.1
#=GS B7RKC1_9RHOB/4-42         AC B7RKC1.1
#=GS E8UDK4_TAYEM/124-156      AC E8UDK4.1
#=GS J1RNL5_9ACTN/60-109       AC J1RNL5.1
#=GS A3X6Q6_9RHOB/99-147       AC A3X6Q6.1
#=GS A0A0B5EAZ6_9RHOB/114-142  AC A0A0B5EAZ6.1
#=GS C7H5A3_9FIRM/54-96        AC C7H5A3.1
#=GS C7H3G1_9FIRM/83-121       AC C7H3G1.1
#=GS A0A088EZP9_9SPHI/83-129   AC A0A088EZP9.1
#=GS D4J9B6_9FIRM/60-103       AC D4J9B6.1
#=GS F3PNR3_9BACE/72-115       AC F3PNR3.1
#=GS A0A0M2NES9_9FIRM/71-110   AC A0A0M2NES9.1
#=GS R5A1K8_9CLOT/54-98        AC R5A1K8.1
#=GS F7KIQ8_9FIRM/59-103       AC F7KIQ8.1
#=GS D4K7D9_9FIRM/83-121       AC D4K7D9.1
#=GS D4L429_9FIRM/64-104       AC D4L429.1
#=GS F7KN00_9FIRM/56-101       AC F7KN00.1
#=GS R7KLL8_9BURK/60-104       AC R7KLL8.1
#=GS J6UC39_9RHOB/31-71        AC J6UC39.1
#=GS D7GT69_9FIRM/70-119       AC D7GT69.1
#=GS K9X8S8_9NOST/67-115       AC K9X8S8.1
#=GS R7JI51_9BACT/76-119       AC R7JI51.1
#=GS U2QZ60_9FIRM/59-103       AC U2QZ60.1
#=GS E7GMA7_CLOSY/59-103       AC E7GMA7.1
#=GS D4K6W8_9FIRM/59-100       AC D4K6W8.1
#=GS C4ZE47_AGARV/54-101       AC C4ZE47.1
#=GS R6U8D6_9CLOT/56-99        AC R6U8D6.1
#=GS Q1W5C9_BACMQ/65-112       AC Q1W5C9.1
#=GS S0R913_9ENTE/75-121       AC S0R913.1
#=GS G9RVH7_9FIRM/59-104       AC G9RVH7.1
#=GS C7H736_9FIRM/65-109       AC C7H736.1
#=GS E1VTE9_ARTAR/101-144      AC E1VTE9.1
#=GS H1YHN3_9SPHI/79-126       AC H1YHN3.1
#=GS K7SLY4_GLUOY/67-114       AC K7SLY4.1
#=GS B9D640_CAMRE/16-58        AC B9D640.1
#=GS Q5HS44_STAEQ/82-131       AC Q5HS44.1
#=GS C4ZEP1_AGARV/59-110       AC C4ZEP1.1
#=GS R5J1D4_9FIRM/26-70        AC R5J1D4.1
#=GS Q5DY55_VIBF1/97-142       AC Q5DY55.1
#=GS C6WSP9_METML/77-122       AC C6WSP9.1
#=GS E0TH04_PARBH/91-131       AC E0TH04.1
#=GS E6K6H3_9BACT/72-115       AC E6K6H3.1
#=GS C7HVB4_9FIRM/30-72        AC C7HVB4.1
#=GS R6TWK1_9FIRM/60-103       AC R6TWK1.1
#=GS G4D741_9FIRM/46-90        AC G4D741.1
#=GS I0TD97_9BACT/70-115       AC I0TD97.1
#=GS D1VTS3_9FIRM/60-104       AC D1VTS3.1
#=GS E0E3T2_9FIRM/56-104       AC E0E3T2.1
#=GS A5WI53_PSYWF/62-106       AC A5WI53.1
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C0EF97_9FIRM/50-94                   ..........tt--ELSAIGRNINQIAKQIN.............aTGSS...Y.QA....D.M.E....EIR...ERLDEIWQ-----lqrh................................
E2ZNE5_9FIRM/52-109                  qlrrmayllqnc-------SNNLNQVAKRAN.............eNGKI...Y.SA....D.L.A....DLR...TRLDELI------sigkqiltklanl.......................
D4K951_9FIRM/85-124                  ...........a--QCSKVGSNLNQLARHFN..............SGGK...D.TE....Q.LrA....QIL...EELSA--------ltn.................................
R6EN78_9FIRM/66-109                  ............-FQIRKIGVNINQATKKIN..............SGYY...D.RK....I.C.E....DLQ...NSLEELNRHFQEL....................................
R6FJB1_9BACE/64-119                  ............-NELSHIGGNLNQSVKRANelsvag..llppeyLREV...L.MP....V.I.R....ETQ...DTLNEIKRELEE-v...................................
C2BGI0_9FIRM/57-81                   .......emstn---ISHTSNNINQIAKRVN..............TT--...-.--....-.-.-....---...-------------si..................................
R5IN56_9FIRM/56-73                   ............LRELSAIGNNINQIAHW--..............----...-.--....-.-.-....---...-------------d...................................
H1D9U8_9FUSO/63-111                  .lrelsslvsrn-------SANLNQIAKAVN.............sTGVI...Y.KD....D.I.E....SIK...KALQ---------delrflse............................
X5DGN6_9BACT/71-119                  ..........fn---LNKIGVNLNQVAKQIN..............-SKK...N.NE....L.T.A....TDR...HTLDKVQQELKQ-cfsslqk.............................
K9VS79_9CYAN/86-128                  ...........a--QLRIAGNNLNQLTKACNs............aVALG...E.PV....-.-.-....---...-------------vvntgllesvqqlire....................
B7C979_9FIRM/69-102                  ........vsey----GKIGSNLNQIAKHFN..............SGGS...Q.SR....A.-.-....---...-------------ieneihq.............................
D4BSD3_BIFBR/70-115                  ...........a-REIDRIGVNVNQIAHWAN.............aNEHI...T.PA....Q.V.E....EIR...ASFDRIERLL---gdl.................................
E9SEI2_RUMAL/59-104                  .........lng---MRIISNNINQVARKAN.............eTNSI...Y.AE....D.V.E....KLR...KEVEALSHTLS--kf..................................
A0A024HL18_PSEKB/55-98               ............INELSRIGNNLNQLARHAN.............sGSSI...T.PN....D.L.A....RIW...HSLELLWAA----fq..................................
I4Z9Y3_9BACT/70-114                  ............IRTVSGMANNLNQIAHRLNa............fGISA...L.NE....D.L.N....ALK...QLINELMKRLK--....................................
R5F0D6_9CLOT/59-103                  ............INEVNRIGININQIVFNNN..............AGLY...S.KE....D.K.T....QLI...AYMRKLNQKIDE-a...................................
J4TBC8_9FIRM/65-104                  ..........at--------NNINQIAKHVN.............sTGII...Y.RD....D.I.N....DMK...KQIEHFSKELWQI....................................
C7H1E4_9FIRM/59-103                  ...........t-AEIQKIGVNVNQIAKRVN.............aTGSV...Y.QE....D.I.E....EIK...EVLAEIWR-----lqrl................................
K0YVK8_9ACTO/89-136                  ............-RKLTGLANNLNQLTRYAHvk..........geLPQH...I.DD....V.L.G....QVE...RSVDEINYLLAS-v...................................
C2BIN6_9FIRM/61-90                   ........llsn------ATNNINQIAKATN..............TTGV...I.YK....-.-.-....---...-------------neiesm..............................
H1YF60_9SPHI/73-129                  .........irk--ELKAIGININQITRHFNad.........kveTHKG...F.YA....-.-.-....---...-------------lkvadqykkvderveillkiiskla...........
F4FI57_VERMA/63-107                  ...........h-RQVRGAATNLNQAVARLH..............ATGE...P.AG....D.L.A....ASA...AYVARIAARVDEL....................................
U2SAX3_9FIRM/59-102                  ............IRELQAVSRNINQIAKRAN.............aTGTV...Y.RQ....D.I.E....DIK...KAVDEIWR-----lqr.................................
A0A0A7I478_9BIFI/70-115              ...........a-REIDHIGVNVNQIAHWAN.............aNEHI...T.PA....Q.V.E....EIR...ASFDRIERLL---gdl.................................
G5KG22_9STRE/61-106                  ...........v-FELRRIGNNINQIARAIN.............qSHLI...S.QE....Q.L.Q....DLS...KGVGELIKEVDK-e...................................
G2GYD8_9ENTR/135-175                 ............-RELAAIGRNLNQIARTLN..............---V...E.FR....D.S.D....KLN...KEL----------idrlleqidg..........................
X5DW39_9CORY/108-149                 ...........d--QLRRIGVNLNQLTRNSN.............sKANV...D.AE....A.L.D....EVR...DEFANL-------rnmi................................
R6UQH5_9FIRM/1-60                    ...........m--ELNRIGVNINQIARAFNar.........vkgM---...-.--....-.-.-....---...-------------gmleeikmepdkkafeslresieglsdevkelradl
F7V0R1_EEGSY/81-137                  ........amea----RRIGVNVNQIARTLNaea........kgrGGML...R.SD....T.L.N....GCE...KGLEEVRGELSKLarevet..............................
K4L0T1_9FIRM/56-100                  ............MRELHAIGGNLNQIAAKAN.............aTGHI...D.RT....V.F.Q....YES...NRLRKVV------ldiqa...............................
A0A0C5L1M1_9SPHN/69-113              ...........q----SRIANNLNQLARQANlg.........tlpV---...-.--....-.-.-....---...-------------tpdteaalaeaaadiaamramlv.............
G9RSI1_9FIRM/60-103                  ..........aa---VSRIATNINHVCRRIN.............sTGHF...Y.DA....D.V.A....ELK...ERMADVWELLK--v...................................
T1ZEK6_STRIT/116-158                 .......lgsat--------NNINQIAKRVN.............sTGVI...Y.KD....D.I.K....DMK...KEIEHFSKELWQI....................................
A0A0D6JKC4_9RHIZ/74-117              ...........v-HQLARIGNNLNQLAHQAN..............-IGY...V.AV....P.M.Q....EIR...SCIDAINQKVAQL....................................
R6B344_9CLOT/57-99                   .....stidhlc--------INVNQIAHHAN.............mQGGI...T.AE....E.A.A....EAK...RLVMEIRKRL---y...................................
E6UCW2_RUMA7/58-89                   ...........m-HELRKIGVNLNQVAYLANt...........fqS---...-.--....-.-.-....---...-------------dkaqtalry...........................
R6LLD8_9FIRM/53-97                   ............LRQQKAIGNNLNQLAVLAN..............TGKV...Q.FA....N.L.D....AAA...QEFAKINVTLRQI....................................
A0A0A8ENI0_9ACTN/110-159             ...........g--QLGKIGSNLNQLTRHLNqdg........awpHHDA...V.QR....L.L.D....RVE...ASIAELDTAVAQ-v...................................
R7EVU0_9FIRM/67-97                   ...........t-RQLRAVGNNLNQLAAKAH.............aLDYV...D.--....-.-.-....---...-------------epvyrd..............................
E2ZJ21_9FIRM/60-103                  .......llqnc-------SNNLNQVAKRVN.............eSGKI...Y.AA....D.L.A....DLR...TRLDELI------digkqi..............................
A0A0N1LFS8_9CAUL/74-112              ..........lg--ELGRVGNNINQIARTVN..............--AG...E.AP....D.V.P....ELR...EALQA--------ylql................................
A0A060RAH8_9BACT/73-118              ..........it--KLTGMANNLNQIAKRAN..............QAGY...F.AAk..tE.S.E....TLA...KEIDNVIKSIE--n...................................
G5K9A3_9STRE/57-104                  ...dlqgllsna-------TNNINQIAKRVN.............sTGII...Y.KD....D.I.N....DMK...KQIEYFSKELWQI....................................
G6F3K6_9PROT/48-93                   .........lva---LSKIGSNINQIARHLN.............mDKTL...S.AQ....E.K.V....KAL...FELASIEQSLGE-l...................................
E7GQ76_CLOSY/59-102                  ............IRELQAVSRNINQIAKRAN.............aTGTV...Y.RQ....D.I.E....DIK...KAVDEIWR-----lqr.................................
D7CEM2_STRBB/151-185                 ...........a--QIARIGNNVNQIARRLN..............-ADG...D.PH....-.-.-....---...-------------pvdaailhrad.........................
A0A0B4S296_9FIRM/57-104              ...dlqgllsna-------TNNINQIAKRVN.............sTGVI...Y.KE....D.I.G....DMK...KEIEHFSKELWQI....................................
C7H894_9FIRM/83-121                  ...........l-AQCSRVGGNLNQLARHFN..............SGGA...D.TE....Q.L.-....---...-------------raklldeladl.........................
A0A0N5E7Q9_TRIMR/70-112              ........taey----GKIGGNLNQIARCLN..............-EYG...A.P-....-.-.-....---...-------------yntlsqevraataelaalk.................
K6T613_9CLOT/54-98                   ...........t-HQLSKIGTNLNQLTRLCH..............QGKI...N.CA....D.I.T....SVN...KLLNDLWEYL---vsi.................................
Q2Y576_NITMU/66-106                  ..........av----NRAGVNLNQIARALN..............--SG...L.GH....S.P.H....ELS...ETLARLNQLLDRL....................................
I4Z251_9RHIZ/65-109                  .........aqt----RAVGVNLNQIARAMN..............QGLV...P.AD....-.-.-....---...-------------atlrkvlediaetidgydql................
V5SHE3_9RHIZ/84-126                  ...........v-REINAIGVNLNQLTRIANas..........glIPPG...L.DQ....V.L.D....EIN...DAL----------drmm................................
F0R4X7_BACSH/73-113                  ............IRSLTGMANNLNQLTRLSH..............----...-.QV....G.F.H....RTQ...RTVTELLQKLKEIi...................................
B0PDJ2_9FIRM/59-103                  ...........t-AEIQKIGVNVNQIARRVN.............aTGNA...Y.QE....D.I.E....EIK...GVLAEIWR-----lqrl................................
W6RW32_9RHIZ/75-123                  ...........l-SDMRAIGVNLNQLARAAN.............sSGHV...D.AK....A.I.S....AQT...ADIQKVVA-----avmlelrr............................
A0A015LA95_9GLOM/61-107              ............LRQLASIGNNLNQIARIMNq............qSKAN...S.AI....D.R.I....AVI...TALAGVERELQRL....................................
F5J133_9PORP/71-112                  ............MRKLAGMANNLNQVAKRVN..............-RNE...F.LQ....V.G.L....DLV...ILAGKI-------kelvd...............................
D7GTX6_9FIRM/59-104                  ...........m-AQLQKIGGNLNQITKRIN.............eTERI...Y.DN....D.M.D....ELK...RLMDEVWKL----erql................................
R6H6W2_9FIRM/60-105                  .........vsl---QRRCSNNLNQVAIQAN.............tYGGI...Y.PE....E.I.A....ALQ...RDYAALW------gplsdl..............................
D9W1D3_9ACTN/185-227                 ............LRQCNRIGVNINQIARALN..............SDLT...P.PD....I.R.Q....RLD...-------------elhdllvliae.........................
D4IJV0_9BACT/9-52                    ...........m-AQLKGIARNLNQLTRSAN..............-AGG...F.AA....E.V.A....PHA...AIITQIEDFLKQL....................................
A0A0F5VWE6_9ACTN/154-201             ...........n--EVASIGRNLNQITKKLNsg..........ghSHPG...D.TA....V.L.A....QTE...RTLDAVGTAVRH-i...................................
R5QCK1_9FIRM/56-100                  ...........a-HELQRIGNNLNQLTRAVN..............AGFV...R.VV....D.L.G....ETK...QEVQKVWQSLNSL....................................
D4YY43_SPHJU/120-158                 ...........w-RELNRIGINLNQATRALN..............-AS-...-.--....-.-.-....---...-------------vmvesgldvareaarvas..................
C5ER89_9FIRM/59-111                  .........vsl---MRRNSNNLNQLTRKVH.............eTGRV...Y.DA....D.L.E....DIS...QRQEQLWKGVEEIltqlsel.............................
A0A060R6T6_9BACT/73-119              ..........it--KLTGMANNLNQIAKRAN..............QAGY...F.AAk..tE.S.E....TLA...KEIDNVIKSIE--nd..................................
D4LWQ1_9FIRM/69-107                  ...........i-SEFGKIGSNLNQIARYFN..............QGGI...L.--....-.-.-....---...-------------ssemrneirkslrdi.....................
J6HA35_9FIRM/57-104                  ...dlqgllsna-------TNNINQIAKRVN.............sTGVI...Y.KE....D.I.G....DMK...KEIEHFSKELWQI....................................
M4S6V3_9SPHN/112-149                 ...........w-RELNRIGINLNQATRALN..............-AS-...-.--....-.-.-....---...-------------vmvesgldvareaarva...................
A5FDM0_FLAJ1/70-120                  ..........ts--ELRAIGNNINQIARKINtlktv....pefkgHLYL...F.EI....Q.R.E....RLF...DKMEEV-------svh.................................
F7UX80_EEGSY/56-104                  ...........a-RELHAIGSNLNQIARKAH..............--VL...N.VV....D.A.A....RYD...AEARKLEAALAEIaaavke..............................
K2GLX2_9RHOB/54-97                   ............LRELARIGNNLNQLARWAN..............-REK...R.GA....D.A.V....AVV...ARLIALDRELAQL....................................
I3YMM6_ALIFI/75-118                  ...........m-AQLKGIARNLNQLTRLAN..............-AKG...L.AA....V.R.V....RHA...AIVTAIEKLLKQI....................................
K6VB62_9ACTN/84-126                  ..........nl---LSGLAVNMNQIARHAN..............TEGE...I.PA....D.F.A....AAV...LAARRASE-----rvrd................................
C6BWE1_DESAD/68-119                  ..........vq------IGSNLNQIAYHLN..............--SG...K.LT....D.L.N....ELK...EAHSEMREQ----fastikamrtlkseide...................
R5B130_9CLOT/55-93                   ............MREFSAIGNNIHQISVKAN..............--AL...G.FI....D.T.Q....KLN...SEFDRLHK-----f...................................
C0EI84_9FIRM/59-107                  .........vsl---QRRCSNNINQVAIHAN..............TYGV...Y.PD....E.I.A....GLQ...QDYAELWGRMN--dilkql..............................
C7HAF4_9FIRM/59-100                  ...........t-AELQKIGVNVNQIARRLN.............sMGPL...Y.TQ....D.V.A....DIK...GALAQIWQ-----l...................................
E6K208_PARDN/79-117                  ...........a--EIHRIGVNINQIAHRVN.............mGGKV...D.IP....T.I.E....RLL...EK-----------adsli...............................
A0A0H4CL83_9ACTN/57-98               ............-RHLGQIGNNLNQVAKATN.............aGAD-...-.--....-.-.-....---...-------------vphtravldavhraakrvet................
G2SYF6_ROSHA/64-104                  ..........et---LGKISGNLNQIAKRIN.............sTGNV...Y.KE....D.M.A....EVK...VIMDEVWK-----t...................................
D4LV94_9FIRM/70-119                  ........taey----GRIGGNLNQIARTLNe...........whS---...-.--....-.-.-....---...-------------pypqlagevraavsdlaalkfevlqkv.........
R5TRI3_9FIRM/36-86                   ..........vy--QFRKIGTNINQATKQLH..............IGYE...P.AA....A.A.D....RLE...KNMKLLEQQFEK-mkeelkq.............................
D3IEH1_9BACT/107-151                 ............IRTVSGMANNINQIAHRLNa............fGIYA...L.NE....D.L.N....ALK...VLIHELIKRLK--....................................
#=GC seq_cons                        ...........h..plttlGsNlNQlA+phN..............tsth...h.tt....p.h.t....ph....t.htth.......h...................................
//
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