GenomeNet

Database: Pfam
Entry: MobC
LinkDB: MobC
Original site: MobC 
#=GF ID   MobC
#=GF AC   PF05713.8
#=GF DE   Bacterial mobilisation protein (MobC)
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_2832 (release 8.0)
#=GF GA   22.00 22.00;
#=GF TC   22.00 22.00;
#=GF NC   21.90 21.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11976306
#=GF RT   Characterization of two cryptic Helicobacter pylori plasmids: a
#=GF RT   putative source for horizontal gene transfer and gene shuffling. 
#=GF RA   Hofreuter D, Haas R; 
#=GF RL   J Bacteriol 2002;184:2755-2766.
#=GF RN   [2]
#=GF RM   9302013
#=GF RT   The relaxosome protein MobC promotes conjugal plasmid
#=GF RT   mobilization by extending DNA strand separation to the nick site
#=GF RT   at the origin of transfer. 
#=GF RA   Zhang S, Meyer R; 
#=GF RL   Mol Microbiol 1997;25:509-516.
#=GF DR   INTERPRO; IPR008687;
#=GF CC   This family consists of several bacterial MobC-like,
#=GF CC   mobilisation proteins. MobC proteins belong to the group of
#=GF CC   relaxases. Together with MobA and MobB they bind to a single
#=GF CC   cis-active site of a mobilising plasmid, the origin of transfer
#=GF CC   (oriT) region [1]. The absence of MobC has several different
#=GF CC   effects on oriT DNA. Site- and strand-specific nicking by MobA
#=GF CC   protein is severely reduced, accounting for the lower frequency
#=GF CC   of mobilisation. The localised DNA strand separation required
#=GF CC   for this nicking is less affected, but becomes more sensitive to
#=GF CC   the level of active DNA gyrase in the cell. In addition, strand
#=GF CC   separation is not efficiently extended through the region
#=GF CC   containing the nick site. These effects suggest a model in which
#=GF CC   MobC acts as a molecular wedge for the relaxosome-induced
#=GF CC   melting of oriT DNA. The effect of MobC on strand separation may
#=GF CC   be partially complemented by the helical distortion induced by
#=GF CC   supercoiling. However, MobC extends the melted region through
#=GF CC   the nick site, thus providing the single-stranded substrate
#=GF CC   required for cleavage by MobA [2]. 
#=GF SQ   517
#=GS G4Q4L7_ACIIR/71-118       AC G4Q4L7.1
#=GS U2RCS5_9FIRM/46-90        AC U2RCS5.1
#=GS I1YRZ2_PREI7/70-114       AC I1YRZ2.1
#=GS A4CGM8_ROBBH/66-108       AC A4CGM8.1
#=GS G8TJG2_NIAKG/68-112       AC G8TJG2.1
#=GS D4JED5_9FIRM/61-113       AC D4JED5.1
#=GS D4K1U1_9FIRM/83-121       AC D4K1U1.1
#=GS W0ES94_9PORP/73-113       AC W0ES94.1
#=GS V6KKV9_STRRC/130-174      AC V6KKV9.1
#=GS C7PJH0_CHIPD/68-123       AC C7PJH0.1
#=GS F3ZAN4_9ACTN/93-140       AC F3ZAN4.1
#=GS R6WAY1_9FIRM/73-115       AC R6WAY1.1
#=GS G4KS41_OSCVS/52-96        AC G4KS41.1
#=GS V4SPA9_STRIN/65-106       AC V4SPA9.1
#=GS R5NTS2_9CLOT/51-91        AC R5NTS2.1
#=GS D4IKK1_9BACT/72-115       AC D4IKK1.1
#=GS D6GPN1_FILAD/57-104       AC D6GPN1.1
#=GS B2JC06_NOSP7/81-136       AC B2JC06.1
#=GS D4M3I9_9FIRM/54-103       AC D4M3I9.1
#=GS A1RDC9_ARTAT/144-187      AC A1RDC9.1
#=GS E7RM52_9BACT/121-164      AC E7RM52.1
#=GS R6WPI6_9BACT/70-113       AC R6WPI6.1
#=GS B8HJI3_ARTCA/53-96        AC B8HJI3.1
#=GS B7K6N2_CYAP8/67-94        AC B7K6N2.1
#=GS R7N4C7_9FIRM/63-108       AC R7N4C7.1
#=GS A0A0B4S1S6_9FIRM/68-109   AC A0A0B4S1S6.1
#=GS C4ZFK0_EUBR3/60-103       AC C4ZFK0.1
#=GS G0HF26_CORVD/79-124       AC G0HF26.1
#=GS D4M204_9FIRM/71-120       AC D4M204.1
#=GS E3I6L8_RHOVT/78-125       AC E3I6L8.1
#=GS R7JFG9_9PORP/72-115       AC R7JFG9.1
#=GS A5VGY8_SPHWW/112-160      AC A5VGY8.1
#=GS H1Y1U3_9SPHI/70-97        AC H1Y1U3.1
#=GS R6PGU8_9CLOT/69-106       AC R6PGU8.1
#=GS A6X801_OCHA4/99-148       AC A6X801.1
#=GS E3GPA0_EUBLK/78-136       AC E3GPA0.1
#=GS S6CB96_9ACTN/56-104       AC S6CB96.1
#=GS R6TNL5_9CLOT/54-98        AC R6TNL5.1
#=GS Q9KYB4_STRCO/121-163      AC Q9KYB4.1
#=GS R7AEW4_9CLOT/57-102       AC R7AEW4.1
#=GS B2JC20_NOSP7/81-136       AC B2JC20.1
#=GS E1VRH1_ARTAR/83-126       AC E1VRH1.1
#=GS A3DKF2_CLOTH/53-92        AC A3DKF2.1
#=GS I3YQU9_ALIFI/75-103       AC I3YQU9.1
#=GS G2IU41_9SPHN/120-158      AC G2IU41.1
#=GS D4H4Q4_DENA2/88-124       AC D4H4Q4.1
#=GS D4L2K1_9FIRM/53-108       AC D4L2K1.1
#=GS I3UHY5_ADVKW/14-60        AC I3UHY5.1
#=GS R4KC44_9FIRM/56-82        AC R4KC44.1
#=GS A6X7N5_OCHA4/99-148       AC A6X7N5.1
#=GS R5QE94_9FIRM/59-103       AC R5QE94.1
#=GS A5VH27_SPHWW/65-114       AC A5VH27.1
#=GS R2PSI2_9ENTE/88-133       AC R2PSI2.1
#=GS D4K4J5_9FIRM/71-120       AC D4K4J5.1
#=GS R6PVU6_9CLOT/59-106       AC R6PVU6.1
#=GS D3LWZ1_9FIRM/57-104       AC D3LWZ1.1
#=GS R6PPQ0_9CLOT/79-124       AC R6PPQ0.1
#=GS Q8A8P0_BACTN/140-179      AC Q8A8P0.1
#=GS I4EB25_METSZ/109-159      AC I4EB25.1
#=GS W6RPZ4_9RHIZ/75-123       AC W6RPZ4.1
#=GS K9UE41_9CHRO/75-131       AC K9UE41.1
#=GS F8ER75_RUNSL/70-113       AC F8ER75.1
#=GS D4MPJ5_9FIRM/57-102       AC D4MPJ5.1
#=GS D4IJW2_9BACT/75-118       AC D4IJW2.1
#=GS R5CBX4_9BACE/75-114       AC R5CBX4.1
#=GS D3Q2W1_STANL/80-123       AC D3Q2W1.1
#=GS D4K3L7_9FIRM/71-107       AC D4K3L7.1
#=GS R5MW63_9FIRM/56-97        AC R5MW63.1
#=GS Q8E0T1_STRA5/24-53        AC Q8E0T1.1
#=GS I3U5U5_ENTFC/108-154      AC I3U5U5.1
#=GS D4M3M4_9FIRM/60-103       AC D4M3M4.1
#=GS R7FEA0_9FIRM/59-103       AC R7FEA0.1
#=GS B0S1X0_FINM2/61-104       AC B0S1X0.1
#=GS D5X3W4_THIK1/80-123       AC D5X3W4.1
#=GS A0AWK1_ARTS2/81-124       AC A0AWK1.1
#=GS A7HZD0_CAMHC/57-98        AC A7HZD0.1
#=GS G2T4N5_ROSHA/183-225      AC G2T4N5.1
#=GS H1YHU1_9SPHI/73-102       AC H1YHU1.1
#=GS A5N4V0_CLOK5/61-111       AC A5N4V0.1
#=GS D4W978_9FIRM/62-107       AC D4W978.1
#=GS H8XSU6_FLAIG/65-106       AC H8XSU6.1
#=GS E6UDU4_RUMA7/114-157      AC E6UDU4.1
#=GS A0A077EIR1_9FLAO/64-102   AC A0A077EIR1.1
#=GS E7GU94_CLOSY/59-100       AC E7GU94.1
#=GS A0A059W9L2_STRA9/147-195  AC A0A059W9L2.1
#=GS A0A060R9M9_9BACT/81-124   AC A0A060R9M9.1
#=GS K7SCY2_GLUOY/54-95        AC K7SCY2.1
#=GS D6DF81_CLOSC/56-94        AC D6DF81.1
#=GS V6K575_STRRC/130-176      AC V6K575.1
#=GS V5SH98_9RHIZ/49-76        AC V5SH98.1
#=GS Q4JTW0_CORJK/70-110       AC Q4JTW0.1
#=GS D4LS38_9FIRM/59-103       AC D4LS38.1
#=GS R5EM74_9FIRM/2-39         AC R5EM74.1
#=GS H1YHD1_9SPHI/75-131       AC H1YHD1.1
#=GS A0A060RCZ0_9BACT/54-99    AC A0A060RCZ0.1
#=GS N2BYV9_9ACTN/59-100       AC N2BYV9.1
#=GS C4Z3W3_EUBE2/66-111       AC C4Z3W3.1
#=GS D6DIX4_CLOSC/59-103       AC D6DIX4.1
#=GS V6KAU0_STRRC/130-175      AC V6KAU0.1
#=GS Q8CYS9_STRR6/61-106       AC Q8CYS9.1
#=GS C7RGW1_ANAPD/61-104       AC C7RGW1.1
#=GS D4KYE9_9FIRM/59-103       AC D4KYE9.1
#=GS D4L0I1_9FIRM/66-107       AC D4L0I1.1
#=GS C0MCH8_STRS7/60-104       AC C0MCH8.1
#=GS R5KCK6_9CLOT/59-103       AC R5KCK6.1
#=GS R6RGE7_9FIRM/48-92        AC R6RGE7.1
#=GS Q188L6_PEPD6/57-104       AC Q188L6.1
#=GS Q07GJ2_ROSDO/71-124       AC Q07GJ2.1
#=GS R6LLG8_9FIRM/53-97        AC R6LLG8.1
#=GS A6LE49_PARD8/75-105       AC A6LE49.1
#=GS G4KUJ3_OSCVS/61-109       AC G4KUJ3.1
#=GS R5E9P9_9CLOT/57-102       AC R5E9P9.1
#=GS Q0AM78_MARMM/66-108       AC Q0AM78.1
#=GS B4RFV6_PHEZH/112-156      AC B4RFV6.1
#=GS R6FQP6_9BACE/67-110       AC R6FQP6.1
#=GS D9SPS7_CLOC7/54-98        AC D9SPS7.1
#=GS R7CXW1_9BACE/72-115       AC R7CXW1.1
#=GS R5S133_9FIRM/60-105       AC R5S133.1
#=GS J1JZ14_9RHIZ/62-107       AC J1JZ14.1
#=GS R5C6L6_9FIRM/57-103       AC R5C6L6.1
#=GS D4MPI3_9FIRM/71-120       AC D4MPI3.1
#=GS Q7MVZ9_PORGI/72-115       AC Q7MVZ9.1
#=GS U7G6T7_9RHOB/50-91        AC U7G6T7.1
#=GS J9SKB5_9ACTN/84-124       AC J9SKB5.1
#=GS A0A0B5EY66_9ACTN/40-91    AC A0A0B5EY66.1
#=GS G4KY18_OSCVS/77-121       AC G4KY18.1
#=GS R7L2F3_9FIRM/60-98        AC R7L2F3.1
#=GS F7V1W5_CLOSS/65-115       AC F7V1W5.1
#=GS B2VAX5_ERWT9/61-107       AC B2VAX5.1
#=GS F3ZL55_9ACTN/160-207      AC F3ZL55.1
#=GS K9X6L0_9NOST/82-138       AC K9X6L0.1
#=GS K9X871_9NOST/82-131       AC K9X871.1
#=GS A0A089LR14_9BACL/56-103   AC A0A089LR14.1
#=GS R5L325_9CLOT/34-77        AC R5L325.1
#=GS E8UDK4_TAYEM/124-156      AC E8UDK4.1
#=GS A0A0B5EAZ6_9RHOB/114-142  AC A0A0B5EAZ6.1
#=GS A0A088EZP9_9SPHI/83-129   AC A0A088EZP9.1
#=GS D4J9B6_9FIRM/60-103       AC D4J9B6.1
#=GS R5A1K8_9CLOT/54-98        AC R5A1K8.1
#=GS D4K7D9_9FIRM/83-121       AC D4K7D9.1
#=GS D4L429_9FIRM/64-104       AC D4L429.1
#=GS R7KLL8_9BURK/60-104       AC R7KLL8.1
#=GS D7GT69_9FIRM/70-119       AC D7GT69.1
#=GS K9X8S8_9NOST/67-115       AC K9X8S8.1
#=GS R7JI51_9BACT/76-119       AC R7JI51.1
#=GS U2QZ60_9FIRM/59-103       AC U2QZ60.1
#=GS E7GMA7_CLOSY/59-103       AC E7GMA7.1
#=GS D4K6W8_9FIRM/59-100       AC D4K6W8.1
#=GS C4ZE47_EUBR3/54-101       AC C4ZE47.1
#=GS R6U8D6_9CLOT/56-99        AC R6U8D6.1
#=GS S0R913_9ENTE/75-121       AC S0R913.1
#=GS E1VTE9_ARTAR/101-144      AC E1VTE9.1
#=GS H1YHN3_9SPHI/79-126       AC H1YHN3.1
#=GS K7SLY4_GLUOY/67-114       AC K7SLY4.1
#=GS Q5HS44_STAEQ/82-131       AC Q5HS44.1
#=GS R5J1D4_9FIRM/26-70        AC R5J1D4.1
#=GS C4ZEP1_EUBR3/59-110       AC C4ZEP1.1
#=GS Q5DY55_VIBF1/97-142       AC Q5DY55.1
#=GS C6WSP9_METML/77-122       AC C6WSP9.1
#=GS E0TH04_PARBH/91-131       AC E0TH04.1
#=GS E6K6H3_9BACT/72-115       AC E6K6H3.1
#=GS R6TWK1_9FIRM/60-103       AC R6TWK1.1
#=GS A5WI53_PSYWF/62-106       AC A5WI53.1
#=GS D2QW28_SPILD/53-93        AC D2QW28.1
#=GS E6K5C3_9BACT/72-115       AC E6K5C3.1
#=GS D4LTS3_9FIRM/56-106       AC D4LTS3.1
#=GS B9JPQ2_AGRRK/70-119       AC B9JPQ2.1
#=GS E1V613_HALED/114-162      AC E1V613.1
#=GS R5PX05_9CLOT/56-86        AC R5PX05.1
#=GS R5A5Y5_9CLOT/57-101       AC R5A5Y5.1
#=GS R7GC41_9CLOT/45-91        AC R7GC41.1
#=GS D4JA94_9FIRM/69-102       AC D4JA94.1
#=GS I3YMH3_ALIFI/62-108       AC I3YMH3.1
#=GS F2KUR9_PREDF/72-115       AC F2KUR9.1
#=GS K9ZPA1_ANACC/59-109       AC K9ZPA1.1
#=GS A0AVX9_ARTS2/82-125       AC A0AVX9.1
#=GS W0EQT9_9PORP/73-113       AC W0EQT9.1
#=GS F0QZH2_BACSH/55-98        AC F0QZH2.1
#=GS D4JXS8_9FIRM/59-103       AC D4JXS8.1
#=GS R7DBN7_9FIRM/69-107       AC R7DBN7.1
#=GS R6LVP8_9FIRM/56-99        AC R6LVP8.1
#=GS A6L6M4_BACV8/75-118       AC A6L6M4.1
#=GS R6M7A1_9FIRM/55-99        AC R6M7A1.1
#=GS R6VXK0_9FIRM/57-98        AC R6VXK0.1
#=GS B3PC92_CELJU/97-128       AC B3PC92.1
#=GS X2H8R8_9NEIS/34-80        AC X2H8R8.1
#=GS R5ET55_9FIRM/60-114       AC R5ET55.1
#=GS A0A088QIS8_9CORY/70-110   AC A0A088QIS8.1
#=GS D6DI76_CLOSC/71-115       AC D6DI76.1
#=GS A0A0D4DF46_9ACTN/119-160  AC A0A0D4DF46.1
#=GS K9ZQT3_ANACC/96-143       AC K9ZQT3.1
#=GS A0A0D1LR33_9LACT/74-116   AC A0A0D1LR33.1
#=GS R5FYS6_9ACTN/60-103       AC R5FYS6.1
#=GS B9K5Y4_AGRVS/72-121       AC B9K5Y4.1
#=GS R7MBR2_9CLOT/56-100       AC R7MBR2.1
#=GS D4K2I8_9FIRM/59-112       AC D4K2I8.1
#=GS R5EDT1_9BURK/134-179      AC R5EDT1.1
#=GS D3IEN8_9BACT/121-164      AC D3IEN8.1
#=GS E6U2P1_ETHHY/59-104       AC E6U2P1.1
#=GS F0R855_BACSH/72-115       AC F0R855.1
#=GS B9ECE6_MACCJ/78-132       AC B9ECE6.1
#=GS R7MA08_9CLOT/56-99        AC R7MA08.1
#=GS B7K6Q1_CYAP8/59-110       AC B7K6Q1.1
#=GS C6RL54_ACIRA/82-129       AC C6RL54.1
#=GS F7V2J3_CLOSS/71-120       AC F7V2J3.1
#=GS D4JD80_9FIRM/69-107       AC D4JD80.1
#=GS I4EAW3_METSZ/68-99        AC I4EAW3.1
#=GS D4LBK2_RUMC1/64-102       AC D4LBK2.1
#=GS C6RLS8_ACIRA/82-130       AC C6RLS8.1
#=GS V5XTT1_ENTMU/68-109       AC V5XTT1.1
#=GS R5YW62_9CLOT/57-100       AC R5YW62.1
#=GS D7GR78_9FIRM/59-110       AC D7GR78.1
#=GS E7GUM8_CLOSY/71-120       AC E7GUM8.1
#=GS W0EV40_9PORP/73-113       AC W0EV40.1
#=GS L0FUT1_ECHVK/72-98        AC L0FUT1.1
#=GS D4Z8L8_SPHJU/116-154      AC D4Z8L8.1
#=GS Q89YW0_BACTN/70-113       AC Q89YW0.1
#=GS D3Q370_STANL/76-120       AC D3Q370.1
#=GS R6QR19_9FIRM/43-68        AC R6QR19.1
#=GS K4REX4_9ACTN/150-191      AC K4REX4.1
#=GS E6JZP9_PARDN/66-110       AC E6JZP9.1
#=GS R6NH79_9CLOT/55-86        AC R6NH79.1
#=GS G2NNL8_STREK/156-195      AC G2NNL8.1
#=GS A0A060QL63_9PROT/81-126   AC A0A060QL63.1
#=GS U4Q8E9_TEPAE/8-51         AC U4Q8E9.1
#=GS G2T376_ROSHA/60-112       AC G2T376.1
#=GS C0MDT9_STRS7/61-106       AC C0MDT9.1
#=GS D4K7Q9_9FIRM/70-128       AC D4K7Q9.1
#=GS D4M3T9_9FIRM/60-103       AC D4M3T9.1
#=GS R7GBG3_9CLOT/58-102       AC R7GBG3.1
#=GS A5FDP8_FLAJ1/70-125       AC A5FDP8.1
#=GS I3WIS5_BIFBI/70-115       AC I3WIS5.1
#=GS Q2Y5A4_NITMU/64-106       AC Q2Y5A4.1
#=GS H1YDX6_9SPHI/69-127       AC H1YDX6.1
#=GS R5YKS6_9CLOT/56-99        AC R5YKS6.1
#=GS A0A099W020_9LIST/59-100   AC A0A099W020.1
#=GS D4L201_9FIRM/54-101       AC D4L201.1
#=GS E0R995_9ENTR/172-212      AC E0R995.1
#=GS H1Y5P7_9SPHI/63-119       AC H1Y5P7.1
#=GS H1Y3X0_9SPHI/116-159      AC H1Y3X0.1
#=GS Q1QRV9_NITHX/72-114       AC Q1QRV9.1
#=GS B1M9T8_METRJ/127-170      AC B1M9T8.1
#=GS L0G3Z2_ECHVK/66-106       AC L0G3Z2.1
#=GS E6UKP3_RUMA7/59-103       AC E6UKP3.1
#=GS D6DKN9_CLOSC/71-118       AC D6DKN9.1
#=GS D4KZT4_9FIRM/66-119       AC D4KZT4.1
#=GS G2NEN0_STREK/130-176      AC G2NEN0.1
#=GS R6YX29_9BACE/78-121       AC R6YX29.1
#=GS E0UNR5_CYAP2/58-106       AC E0UNR5.1
#=GS A0A060R9V1_9BACT/44-67    AC A0A060R9V1.1
#=GS D4JZT0_9FIRM/60-103       AC D4JZT0.1
#=GS U2SJ87_9FIRM/60-100       AC U2SJ87.1
#=GS R5BLP7_9FIRM/69-117       AC R5BLP7.1
#=GS R6HUJ4_9FIRM/72-130       AC R6HUJ4.1
#=GS A0A077EGL6_9FLAO/64-102   AC A0A077EGL6.1
#=GS I3Z991_BELBD/78-121       AC I3Z991.1
#=GS Q5LA95_BACFN/72-115       AC Q5LA95.1
#=GS R5B0C0_9BACE/48-91        AC R5B0C0.1
#=GS R6VQJ8_9FIRM/56-100       AC R6VQJ8.1
#=GS R7JAU1_9PORP/76-119       AC R7JAU1.1
#=GS D4JDG5_9FIRM/56-98        AC D4JDG5.1
#=GS R5KCH7_9BACT/82-125       AC R5KCH7.1
#=GS K4L0M1_9FIRM/56-102       AC K4L0M1.1
#=GS B0S396_FINM2/61-104       AC B0S396.1
#=GS E6UCL8_RUMA7/58-92        AC E6UCL8.1
#=GS Q11N59_CHESB/71-122       AC Q11N59.1
#=GS B2JXY7_BURP8/71-114       AC B2JXY7.1
#=GS B1VFE0_CORU7/70-110       AC B1VFE0.1
#=GS R5RUQ0_9FIRM/56-100       AC R5RUQ0.1
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G4Q4L7_ACIIR/71-118                  .......taey----GKIGGNLNQIARSLNe.........ygS---...-.--..-.-.-....---...-------------pyrglekevrgaaadlaalkfevlq...........
U2RCS5_9FIRM/46-90                   ...........-RQLAAIGNNINQIARAVN...........aRGFA...S.GE..D.I.A....AIT...AAQETIWN-----iaerl...............................
I1YRZ2_PREI7/70-114                  ...........IRTVSGMANNLNQIVHRLNa..........fGIYA...L.NE..D.L.N....ALK...VLIHELIKRLK--....................................
A4CGM8_ROBBH/66-108                  ..........i--ELGRIGNNLNQLTKKVH...........lGMNN...S.PI..L.I.E....HLS...AM-----------rstldtlka...........................
G8TJG2_NIAKG/68-112                  ...........LAELGKIGSNVNQIAKALN............TDLA...A.HQ..Q.I.S....VPS...ELMTATLYALQTL....................................
D4JED5_9FIRM/61-113                  ........vsl---LRRSSNNLNQLTRKVH...........eTGRI...Y.DV..D.L.E....DIS...QRQEQLWDGVKEIltqlskl.............................
D4K1U1_9FIRM/83-121                  ..........l-AQCSKVGTNLNQLARHFN............SGGA...D.TE..Q.I.-....---...-------------raklldeladl.........................
W0ES94_9PORP/73-113                  ...........IRSLTGMANNLNQLTRLSH............----...-.QA..G.F.H....RTQ...KTVTELLQKLKEIi...................................
V6KKV9_STRRC/130-174                 ...........LRELNRIGVNVNQIARALN............-SDL...T.PP..D.L.R....QRL...AELQQLLELI---aeal................................
C7PJH0_CHIPD/68-123                  ..........l-SELGKNGSNINQIAKIMNadn.....ktsySVSV...K.ED..L.I.A....AAL...EEIRQ--------ttakivqaleqt........................
F3ZAN4_9ACTN/93-140                  ..........g--QLGKVGSNLNQLARHMN............-MEG...E.WP..L.A.D....TVM...RLLARVEASI---advdtava............................
R6WAY1_9FIRM/73-115                  ...........----GKIGVNLNQIARYFNtg........geRSLA...M.ED..E.I.R....HCI...AEL----------falreevl............................
G4KS41_OSCVS/52-96                   ..........l-KQQRAIGNNLNQLTVLAN............MGRV...S.VA..N.L.S....ETA...QALKTISETLQEI....................................
V4SPA9_STRIN/65-106                  .........av----NRIGGNINQIAKHAN...........eNQNI...S.TE..Q.L.T....QVL...DYLSEIK------dmva................................
R5NTS2_9CLOT/51-91                   .........et---LGKISGNLNQIAKRII...........sTGNV...Y.EE..D.I.A....EVK...AIMDEVWR-----m...................................
D4IKK1_9BACT/72-115                  ...........IRKLAGEANNINQLAHRAN............-AGG...F.AL..V.A.V....ELV...KLKNRIVEIINQL....................................
D6GPN1_FILAD/57-104                  ..dlqgllsna-------TNNINQIANRVN...........sTGVI...Y.KE..D.I.G....DMK...QEIEHFSKELWQI....................................
B2JC06_NOSP7/81-136                  .........iy--ELKKIGNNLNQQTRAINe..........aVKIG...S.QP..L.T.V....EVK...SYLITIE------eltelleqtrqsltq.....................
D4M3I9_9FIRM/54-103                  .......taey----GKIGGNLNQIARALN............-EYG...-.--..-.-.-....---...-------------tpyntlsgevraaiadlaalkfevlrkv........
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R7QVM8_9FIRM/36-79                   ..........y--QIRKIGVNVNQTTKKIN............AGFG...T.QL..D.I.E....IME...EELKKMNAAIEQL....................................
D5X1L7_THIK1/24-67                   ..........r--ALARVGSNLNQIAAALN............SARL...-.--..-.-.-....---...-------------tgaampsladirdallalrstl..............
X5DNN4_9BACT/84-133                  ..........y--ELNRIGVNLNQLSKKMNsfs......aynVGDN...D.RQ..L.L.K....QAF...QMMMQCLAFLQ--kh..................................
Q6AG08_LEIXX/76-116                  ..........a---LSRIGNNVNQIAALAN...........tEENA...T.FE..Q.V.Q....AVR...KLLVEL-------qgvv................................
R5KHJ0_9CLOT/77-121                  ...........-RQLIGIGRNINQIAHCFN............AGQY...G.VV..D.L.S....RLD...QPLADV-------tamkqave............................
D2QVY1_SPILD/72-115                  ...........LNQVARLGSNLNQIAHKAN............-ADG...I.RS..I.A.I....EAN...RLLHQLSQLLNK-s...................................
K9VBA9_9CYAN/67-115                  ..........y-EELNAIGVNLNQIAKAVNra........vkSGRG...A.NV..D.A.G....RLQ...NLVDRLNAAIRE-t...................................
A8ART6_CITK8/57-101                  ...........LRQLAGMGNNLNQIARKIN............GGQW...S.GA..D.R.V....QVV...AALMAIDAGLERL....................................
R6NY28_9CLOT/71-120                  .......taey----GRIGNNLNQIARHLNewrs....pypaMAKE...L.QD..A.A.A....DLA...T------------lkfevmkkv...........................
B1X3E0_CYAA5/91-134                  ..........t-RQIARIGNNLNQIAKWAN............-TYK...Q.TA..E.A.I....EVI...QALRLIQETLHEL....................................
R6GLF1_9FIRM/56-101                  ...........LRQLSGMAVNINQIAKVAN...........aRGFV...R.ME..D.I.D....HIK...AMQGLLWRTMKRL....................................
G8UMW9_TANFA/1-40                    ...........------MANNVNQIAHKAN...........aMGYA...RvYQ..D.N.L....VMT...ERLDNIIKRI---ed..................................
D4K3J9_9FIRM/60-112                  ........vsl---QRRCSNNLNQVAIQAN...........tYGAI...Y.PE..E.L.A....ALQ...RDYAALW------gplsdllkqlsal.......................
D4JDK5_9FIRM/56-99                   ...........MRELHRIGGNLNQIAQKAH............----...-.--..-.-.-....---...-------------vlgviderrydeemrkfdqlvrdit...........
L0FVI8_ECHVK/66-106                  ..........v--ELKRIGNNINQIAKQLN............---S...K.FE..V.P.A....DRM...KAIDAISTKLDQV....................................
E3GME8_EUBLK/65-109                  ...........LMQIRKIGTNLNQIAKLAN............MHKI...E.EV..Y.L.Q....ECQ...KELAEIVKMLERI....................................
L0H2C0_9GAMM/58-108                  ...........-RQLRGLGINLNQLAHAANe.........grPVAV...N.QK..M.L.A....DIR...ASLRETRTLLAE-ikerl...............................
G0J0B6_CYCMS/66-94                   .........aa--EQGRVNNNINQLARHAN............-QYS...-.--..-.-.-....---...-------------kvsdldp.............................
L0JHZ0_PREDD/78-122                  .........ak--DLSMLGANVNQIAKYCN............QHQH...E.AP..N.Y.D....GLE...YNIKAVRERLDEI....................................
D4KA54_9FIRM/59-111                  ........vsl---MRRSSNNLNQLTRKVH...........eTGRV...Y.NA..D.L.E....DIS...QRQEQLWEGVKEIltqlskl.............................
D4JTZ7_9FIRM/59-111                  ........vsl---MRRSSNNLNQLTRKVH...........eTGRV...Y.NA..D.L.E....DIS...QRQEQLWEGVKEIltqlskl.............................
D3LWX2_9FIRM/183-217                 .......taey----GRIGGNLNQIARYLN............-EYG...-.--..-.-.-....---...-------------vpyntlsgevraa.......................
A0A060RE17_9BACT/38-61               ..........i-TKLTGMANNLNQIAKRAN............QA--...-.--..-.-.-....---...-------------gcr.................................
E7RPP5_9BACT/72-115                  ...........IRKLCGMANNLNQLAHRAN............-ADG...F.HV..V.A.P....FHK...IIIGKIDEILN--li..................................
F9T6S2_9VIBR/73-116                  .........la----NKVSNNLNQLAKRVH............--QS...H.RA..D.V.V....DKN...LYIRTLN------tlqdlqklw...........................
D4J5X7_9FIRM/56-101                  ...........LRKIAGLCNNANQLAHVAN...........aSGMA...S.EQ..S.I.Q....EML...RLTKETWHLVK--ee..................................
R5UYH2_9FIRM/115-159                 ........rlv----GSISNNINQIAVRAN...........sTNKV...Y.TE..D.I.V....NIK...EGQDKIWQLLNSL....................................
D4K532_9FIRM/59-110                  ........isl---QRRCSNNLNQVAIHAH............TYGV...Y.PE..E.I.D....GLK...RDYEKLWGEVS--kvlrelsel...........................
K7RWF8_PROA4/79-123                  ..........f-RLLGTIANNVNQIARATN............ATGQ...I.QD..D.L.G....GTL...EAVRRVGDRLDSL....................................
G2SZX6_ROSHA/142-190                 .......taey----GRIGGNLNQIARTLNe.........whS---...-.--..-.-.-....---...-------------pypqlagevraavsdlaalkfeilqk..........
U2SIV6_9FIRM/43-96                   vvvidglkevl-KELKSIGRNLNQLVTLAH............MGRV...T.VI..N.L.D....GVR...QTFSEL-------caavrl..............................
G2T4X4_ROSHA/59-103                  ...........INEVNRIGININQIVFNNN............AGLY...S.KE..D.K.T....QLV...AYMRKLNKKVNE-a...................................
B5GPI2_STRC2/159-202                 ..........t-AQLARAGNNLNQVARVLN............SGGH...S.DA..V.-.-....---...-------------dqtvgrvqraavrveaa...................
G4KUH0_OSCVS/134-175                 ..........t-VQLKAIGKNLNQLTVLCN............MGRI...T.CP..D.L.T....EIK...RSFGAV-------fdsi................................
A1VX77_POLNA/74-120                  ...........LRQLVGMGNNLNQIAKLANi..........aSKTA...Q.PM..A.M.V....ELL...ITLKGIEKSLEKL....................................
C7JB51_ACEP3/64-106                  ..........h--QLSRVGNNLNQLARSAN............--CG...D.TI..Q.C.G....CVL...DEIDVLIRQLDQ-ml..................................
E0UNH0_CYAP2/58-106                  ..........l--KLGKISNNINQITKVLNth.......nkfNANV...P.YD..V.I.F....ELK...EQLANVSTQIDQI....................................
T1ZDL7_STRIT/57-104                  ..dlqgllsna-------TNNINQIAKRVN...........sTGII...Y.KE..D.I.N....DMK...KEIEHFSKELWQI....................................
A0A0B4XBJ7_9RHIZ/75-123              ..........i-SDMRSVGVNLNQLARSAN...........aSGRL...S.DA..D.L.AlelrEVQ...RLVAAV-------vlelrs..............................
R6PFF9_9CLOT/69-107                  .......vsey----GKIGSNLNQIARYFN...........sGGDR...S.--..-.-.-....---...-------------raveeeihqcisal......................
R6NK89_9CLOT/57-98                   ...........-RDLYGIANNINQIAKVAN...........sRYSV...S.HD..-.-.-....---...-------------dykyisntladfilrf....................
R7NW21_9BACE/74-116                  ...........IRNLTGMANNLNQLTKLSH............-QTG...F.YR..T.K.N....IVV...ELLEKLK------simnd...............................
D4K951_9FIRM/85-124                  ..........a--QCSKVGSNLNQLARHFN............SGGK...D.TE..Q.LrA....QIL...EELSA--------ltn.................................
R6EN78_9FIRM/66-109                  ...........-FQIRKIGVNINQATKKIN............SGYY...D.RK..I.C.E....DLQ...NSLEELNRHFQEL....................................
R6FJB1_9BACE/64-119                  ...........-NELSHIGGNLNQSVKRANelsvagllppeyLREV...L.MP..V.I.R....ETQ...DTLNEIKRELEE-v...................................
R5IN56_9FIRM/56-73                   ...........LRELSAIGNNINQIAHW--............----...-.--..-.-.-....---...-------------d...................................
K9VS79_9CYAN/86-128                  ..........a--QLRIAGNNLNQLTKACNs..........aVALG...E.PV..-.-.-....---...-------------vvntgllesvqqlire....................
X5DGN6_9BACT/71-119                  .........fn---LNKIGVNLNQVAKQIN............-SKK...N.NE..L.T.A....TDR...HTLDKVQQELKQ-cfsslqk.............................
D4BSD3_BIFBR/70-115                  ..........a-REIDRIGVNVNQIAHWAN...........aNEHI...T.PA..Q.V.E....EIR...ASFDRIERLL---gdl.................................
A0A024HL18_PSEKB/55-98               ...........INELSRIGNNLNQLARHAN...........sGSSI...T.PN..D.L.A....RIW...HSLELLWAA----fq..................................
I4Z9Y3_9BACT/70-114                  ...........IRTVSGMANNLNQIAHRLNa..........fGISA...L.NE..D.L.N....ALK...QLINELMKRLK--....................................
R5F0D6_9CLOT/59-103                  ...........INEVNRIGININQIVFNNN............AGLY...S.KE..D.K.T....QLI...AYMRKLNQKIDE-a...................................
H1YF60_9SPHI/73-129                  ........irk--ELKAIGININQITRHFNad.......kveTHKG...F.YA..-.-.-....---...-------------lkvadqykkvderveillkiiskla...........
F4FI57_VERMA/63-107                  ..........h-RQVRGAATNLNQAVARLH............ATGE...P.AG..D.L.A....ASA...AYVARIAARVDEL....................................
U2SAX3_9FIRM/59-102                  ...........IRELQAVSRNINQIAKRAN...........aTGTV...Y.RQ..D.I.E....DIK...KAVDEIWR-----lqr.................................
G5KG22_9STRE/61-106                  ..........v-FELRRIGNNINQIARAIN...........qSHLI...S.QE..Q.L.Q....DLS...KGVGELIKEVDK-e...................................
X5DW39_9CORY/108-149                 ..........d--QLRRIGVNLNQLTRNSN...........sKANV...D.AE..A.L.D....EVR...DEFANL-------rnmi................................
R6UQH5_9FIRM/1-60                    ..........m--ELNRIGVNINQIARAFNar.......vkgM---...-.--..-.-.-....---...-------------gmleeikmepdkkafeslresieglsdevkelradl
F7V0R1_EEGSY/81-137                  .......amea----RRIGVNVNQIARTLNaea......kgrGGML...R.SD..T.L.N....GCE...KGLEEVRGELSKLarevet..............................
K4L0T1_9FIRM/56-100                  ...........MRELHAIGGNLNQIAAKAN...........aTGHI...D.RT..V.F.Q....YES...NRLRKVV------ldiqa...............................
T1ZEK6_STRIT/116-158                 ......lgsat--------NNINQIAKRVN...........sTGVI...Y.KD..D.I.K....DMK...KEIEHFSKELWQI....................................
A0A0C5L1M1_9SPHN/69-113              ..........q----SRIANNLNQLARQANlg.......tlpV---...-.--..-.-.-....---...-------------tpdteaalaeaaadiaamramlv.............
R6B344_9CLOT/57-99                   ....stidhlc--------INVNQIAHHAN...........mQGGI...T.AE..E.A.A....EAK...RLVMEIRKRL---y...................................
E6UCW2_RUMA7/58-89                   ..........m-HELRKIGVNLNQVAYLANt.........fqS---...-.--..-.-.-....---...-------------dkaqtalry...........................
R6LLD8_9FIRM/53-97                   ...........LRQQKAIGNNLNQLAVLAN............TGKV...Q.FA..N.L.D....AAA...QEFAKINVTLRQI....................................
R7EVU0_9FIRM/67-97                   ..........t-RQLRAVGNNLNQLAAKAH...........aLDYV...D.--..-.-.-....---...-------------epvyrd..............................
A0A0A8ENI0_9ACTN/110-159             ..........g--QLGKIGSNLNQLTRHLNqdg......awpHHDA...V.QR..L.L.D....RVE...ASIAELDTAVAQ-v...................................
A0A060RAH8_9BACT/73-118              .........it--KLTGMANNLNQIAKRAN............QAGY...F.AAktE.S.E....TLA...KEIDNVIKSIE--n...................................
E7GQ76_CLOSY/59-102                  ...........IRELQAVSRNINQIAKRAN...........aTGTV...Y.RQ..D.I.E....DIK...KAVDEIWR-----lqr.................................
D7CEM2_STRBB/151-185                 ..........a--QIARIGNNVNQIARRLN............-ADG...D.PH..-.-.-....---...-------------pvdaailhrad.........................
A0A0B4S296_9FIRM/57-104              ..dlqgllsna-------TNNINQIAKRVN...........sTGVI...Y.KE..D.I.G....DMK...KEIEHFSKELWQI....................................
V5SHE3_9RHIZ/84-126                  ..........v-REINAIGVNLNQLTRIANas........glIPPG...L.DQ..V.L.D....EIN...DAL----------drmm................................
Q2Y576_NITMU/66-106                  .........av----NRAGVNLNQIARALN............--SG...L.GH..S.P.H....ELS...ETLARLNQLLDRL....................................
F0R4X7_BACSH/73-113                  ...........IRSLTGMANNLNQLTRLSH............----...-.QV..G.F.H....RTQ...RTVTELLQKLKEIi...................................
W6RW32_9RHIZ/75-123                  ..........l-SDMRAIGVNLNQLARAAN...........sSGHV...D.AK..A.I.S....AQT...ADIQKVVA-----avmlelrr............................
D7GTX6_9FIRM/59-104                  ..........m-AQLQKIGGNLNQITKRIN...........eTERI...Y.DN..D.M.D....ELK...RLMDEVWKL----erql................................
R6H6W2_9FIRM/60-105                  ........vsl---QRRCSNNLNQVAIQAN...........tYGGI...Y.PE..E.I.A....ALQ...RDYAALW------gplsdl..............................
D4IJV0_9BACT/9-52                    ..........m-AQLKGIARNLNQLTRSAN............-AGG...F.AA..E.V.A....PHA...AIITQIEDFLKQL....................................
R5QCK1_9FIRM/56-100                  ..........a-HELQRIGNNLNQLTRAVN............AGFV...R.VV..D.L.G....ETK...QEVQKVWQSLNSL....................................
D4YY43_SPHJU/120-158                 ..........w-RELNRIGINLNQATRALN............-AS-...-.--..-.-.-....---...-------------vmvesgldvareaarvas..................
A0A060R6T6_9BACT/73-119              .........it--KLTGMANNLNQIAKRAN............QAGY...F.AAktE.S.E....TLA...KEIDNVIKSIE--nd..................................
D4LWQ1_9FIRM/69-107                  ..........i-SEFGKIGSNLNQIARYFN............QGGI...L.--..-.-.-....---...-------------ssemrneirkslrdi.....................
M4S6V3_9SPHN/112-149                 ..........w-RELNRIGINLNQATRALN............-AS-...-.--..-.-.-....---...-------------vmvesgldvareaarva...................
F7UX80_EEGSY/56-104                  ..........a-RELHAIGSNLNQIARKAH............--VL...N.VV..D.A.A....RYD...AEARKLEAALAEIaaavke..............................
A5FDM0_FLAJ1/70-120                  .........ts--ELRAIGNNINQIARKINtlktv..pefkgHLYL...F.EI..Q.R.E....RLF...DKMEEV-------svh.................................
I3YMM6_ALIFI/75-118                  ..........m-AQLKGIARNLNQLTRLAN............-AKG...L.AA..V.R.V....RHA...AIVTAIEKLLKQI....................................
R5B130_9CLOT/55-93                   ...........MREFSAIGNNIHQISVKAN............--AL...G.FI..D.T.Q....KLN...SEFDRLHK-----f...................................
C6BWE1_DESAD/68-119                  .........vq------IGSNLNQIAYHLN............--SG...K.LT..D.L.N....ELK...EAHSEMREQ----fastikamrtlkseide...................
E6K208_PARDN/79-117                  ..........a--EIHRIGVNINQIAHRVN...........mGGKV...D.IP..T.I.E....RLL...EK-----------adsli...............................
G2SYF6_ROSHA/64-104                  .........et---LGKISGNLNQIAKRIN...........sTGNV...Y.KE..D.M.A....EVK...VIMDEVWK-----t...................................
D4LV94_9FIRM/70-119                  .......taey----GRIGGNLNQIARTLNe.........whS---...-.--..-.-.-....---...-------------pypqlagevraavsdlaalkfevlqkv.........
R5TRI3_9FIRM/36-86                   .........vy--QFRKIGTNINQATKQLH............IGYE...P.AA..A.A.D....RLE...KNMKLLEQQFEK-mkeelkq.............................
D3IEH1_9BACT/107-151                 ...........IRTVSGMANNINQIAHRLNa..........fGIYA...L.NE..D.L.N....ALK...VLIHELIKRLK--....................................
#=GC seq_cons                        ..........h..plptlGsNlNQlA+tsN............tsth.....tt..t.h.t....ph....t.htph.......h...................................
//
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