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Database: Pfam
Entry: MotCF
LinkDB: MotCF
Original site: MotCF 
#=GF ID   MotCF
#=GF AC   PF09158.6
#=GF DE   Bacteriophage T4 MotA, C-terminal
#=GF AU   Sammut SJ
#=GF SE   pdb_1kaf
#=GF GA   25.00 25.00;
#=GF TC   29.30 28.20;
#=GF NC   22.60 18.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   11918797
#=GF RT   The MotA transcription factor from bacteriophage T4 contains a
#=GF RT   novel DNA-binding domain: the 'double wing' motif. 
#=GF RA   Li N, Sickmier EA, Zhang R, Joachimiak A, White SW; 
#=GF RL   Mol Microbiol. 2002;43:1079-1088.
#=GF DR   INTERPRO; IPR015241;
#=GF DR   SCOP; 1kaf; fa;
#=GF CC   Members of this family adopt a compact alpha/beta structure
#=GF CC   comprising three alpha-helices and six beta-strands in the
#=GF CC   order: alpha1-beta1-beta2-beta3-beta4-alpha2-beta5-beta6-alpha3.
#=GF CC   The beta-strands form a single anti-parallel beta-sheet and the
#=GF CC   three alpha-helices pack side-by-side onto one surface of the
#=GF CC   beta-sheet. In this architecture, the domain's hydrophobic core
#=GF CC   is at the sheet-helix interface, and the second surface of the
#=GF CC   beta-sheet is completely exposed. The domain is a DNA-binding
#=GF CC   motif, with a consensus sequence containing nine base pairs
#=GF CC   (5'-TTTGCTTTA-3'), that appears to bind to various mot boxes,
#=GF CC   allowing access to the minor groove towards the 5'-end of this
#=GF CC   sequence and the major groove towards the 3'-end [1].
#=GF SQ   40
#=GS I6ZYI8_9VIRU/106-208      AC I6ZYI8.1
#=GS W6ATQ7_9CAUD/107-211      AC W6ATQ7.1
#=GS J7I561_9CAUD/112-213      AC J7I561.1
#=GS A0A023ZV77_9CAUD/106-208  AC A0A023ZV77.1
#=GS Q7Y4P8_BPR69/107-209      AC Q7Y4P8.1
#=GS I6YYC0_9CAUD/112-213      AC I6YYC0.1
#=GS K4I1Y1_9CAUD/107-211      AC K4I1Y1.1
#=GS Q56EC9_9CAUD/111-212      AC Q56EC9.1
#=GS Q06E72_BPR32/106-208      AC Q06E72.1
#=GS D9IEU6_BPT4/106-208       AC D9IEU6.1
#=GS I7KRX2_9CAUD/106-208      AC I7KRX2.1
#=GS G1FHI0_9CAUD/106-208      AC G1FHI0.1
#=GS E5E4L7_9CAUD/109-209      AC E5E4L7.1
#=GS G3MUJ6_9CAUD/37-139       AC G3MUJ6.1
#=GS E5DI00_9CAUD/107-211      AC E5DI00.1
#=GS I6YMQ6_9CAUD/112-213      AC I6YMQ6.1
#=GS K4FF15_9CAUD/106-208      AC K4FF15.1
#=GS C4MZZ7_9CAUD/108-209      AC C4MZZ7.1
#=GS A8R9P6_9CAUD/108-209      AC A8R9P6.1
#=GS Q19CD8_9CAUD/130-213      AC Q19CD8.1
#=GS F2VXJ4_9CAUD/106-208      AC F2VXJ4.1
#=GS E5EQ31_9CAUD/101-202      AC E5EQ31.1
#=GS A0A023W6X3_9CAUD/105-209  AC A0A023W6X3.1
#=GS E1A172_9CAUD/112-213      AC E1A172.1
#=GS E5FJ40_9CAUD/101-201      AC E5FJ40.1
#=GS S5MLB3_9CAUD/106-208      AC S5MLB3.1
#=GS D9I6I5_9CAUD/92-187       AC D9I6I5.1
#=GS I3WVY4_9CAUD/99-202       AC I3WVY4.1
#=GS I7LHB8_9CAUD/117-218      AC I7LHB8.1
#=GS Q6U967_9CAUD/111-212      AC Q6U967.1
#=GS E5EZ21_9CAUD/97-192       AC E5EZ21.1
#=GS G0X5A8_9CAUD/106-208      AC G0X5A8.1
#=GS J7KLW0_9CAUD/112-213      AC J7KLW0.1
#=GS D7RMQ7_9CAUD/132-234      AC D7RMQ7.1
#=GS C3V1W9_9CAUD/106-208      AC C3V1W9.1
#=GS M1EAS7_9CAUD/107-211      AC M1EAS7.1
#=GS D4ZA65_BPAR1/106-208      AC D4ZA65.1
#=GS E3SF76_9CAUD/101-201      AC E3SF76.1
#=GS C3V2P4_BPR51/106-208      AC C3V2P4.1
#=GS MOTA_BPT4/106-208         AC P22915.1
#=GS MOTA_BPT4/106-208         DR PDB; 1KAF B; 106-208;
#=GS MOTA_BPT4/106-208         DR PDB; 1KAF E; 109-208;
#=GS MOTA_BPT4/106-208         DR PDB; 1KAF F; 108-208;
#=GS MOTA_BPT4/106-208         DR PDB; 1KAF A; 106-208;
#=GS MOTA_BPT4/106-208         DR PDB; 1KAF C; 106-208;
#=GS MOTA_BPT4/106-208         DR PDB; 1KAF D; 108-208;
I6ZYI8_9VIRU/106-208                 ............................ITSDMEEDKDLMLKLLD..E..NGFVLKKVETYRSNYLAILEKR.T.HGIRNFEINNNGNMRIFGYKMMEHHIQKF.TDIGMSCKIAKNG.N.VYLDIKR.SAENIEAVITVA.....
W6ATQ7_9CAUD/107-211                 ............................ITDQMEADKNLMMELLAtkD..NLFTIKKLDVYRSNFIAVLEKR.T.FGIRSFEVSNKGNFRISGYKMTEEQVKHF.EDLGMVAKHSKNG.N.VYLDIPR.TQENIENIIH--av...
J7I561_9CAUD/112-213                 ............................ITVEMTKNIELVERLLS..N..LGIEHKQAVINRQNYEITLNKRhA.DGYRKFEILNRGIFRIVGYKVSEEIINNF.KTLGCEIKQG-PA.N.CYIDITA.NENNIV------rlmee
A0A023ZV77_9CAUD/106-208             ............................ITSDMEEDKDFMLKLLD..E..NGFVLKKVETYRSNYLAILEKR.T.HGIRNFEINNNGNMRIFGYKMMEHHIQKF.TDIGMSCKIAKNG.N.VYLDIKR.SAENIEAVITVA.....
Q7Y4P8_BPR69/107-209                 ............vtpemhelanfvfeni-----------------..K..DKVEVKEIGENRSNLEVRFAKR.V.LGIRQIEIRRDGALRIFAYNMSETESKLF.TSLENDVKIKIGG.KyTYIDFPN.VSKEIITLVT--nv...
I6YYC0_9CAUD/112-213                 ............................ITVEMTKNVELIERLLS..N..LGIEHKQAVINRQNYEITLNKRhA.DGYRKFEILNRGIFRIVGYKVSEEIINNF.KTLGCEIKQG-PA.N.CYIDITA.NEHNIV------rlmes
K4I1Y1_9CAUD/107-211                 ............................ITGDMEADKDFMMELLG..TkeELFKIKKLDVYRSNFIAVLEKR.T.FGIRSFEVSNKGNFRISGYKMTEEQVKHF.EDLGMIAKHSKNG.N.VYLDIVR.TQENIETIIN--sv...
Q56EC9_9CAUD/111-212                 .................itaemtglmek-----------ISALV-..E..ENIGLKAVEIYRQNYQIIFSKR.TaEGYRKFEVLNNGKFRIFGYKVAEDKLEAF.RQVGAEIKVG-GS.N.TYIDIEQ.NEVNIAKVMQIA.....
Q06E72_BPR32/106-208                 ............................ITSDMEEDKDLMLKLLD..E..NGFVLKKVETYRSNYLAILEKR.T.HGIRNFEINNNGNMRIFGYKMMEHHIQKF.TDIGMSCKIAKNG.N.VYLDIKR.SAENIEAVIAVA.....
D9IEU6_BPT4/106-208                  ............................ITSDMEEDKDLMLKLLD..K..NGFVLKKVEIYRSNYLAILEKR.T.NGIRNFEINNNGNMRIFGYKMMEHHIQKF.TDIGMSCKIAKNG.N.VYLDIKR.SAENIEAVITVA.....
I7KRX2_9CAUD/106-208                 ............................ITSDMEEDKDLMLKLLD..E..NGFVLKKVETYRSNYLAILEKR.T.HGIRNFEINNNGNMRIFGYKMMEHHIQKF.TDIGMSCKIAKNG.N.VYLDIKR.SVENIEAVITVA.....
G1FHI0_9CAUD/106-208                 ............................ITSDMEEDKDFMLKLLD..E..NGFVLKKVETYRSNYLAILEKR.T.HGIRNFEINNNGNMRIFGYKMMEHHIQKF.TDIGMSCKIAKNG.N.VYLDIKR.SAENIEAVITVA.....
E5E4L7_9CAUD/109-209                 .........................ihe---CMEAFKDFALEYLT..D..K-IEVKNTVVDRSNFLILFAKR.I.SSVGALEIKNKGEVRVVGRKPSDKVVEKL.ASIGMKYRQT-PA.Q.TYFDIEC.TEDNIVNII---dal..
G3MUJ6_9CAUD/37-139                  ...........vtpemvtladevkalle-----------------..-..DRIEIREIAENRSNLEVRFAKR.T.NGIRQIEVRRDGMMRIFGYNMTDKEKQVF.TSLNLDVKIKTGGkN.TYIDFQNvSSEVIKTV----tna..
E5DI00_9CAUD/107-211                 ............................ITDQMEADKNLMMEILAtkD..NLFTIKKLDVYRSNFIAVLEKR.T.FGIRSFEVSNKGNFRISGYKMTEEQVKHF.EDLGMVAKHSKNG.N.VYLDIPR.TQENIENIIH--av...
I6YMQ6_9CAUD/112-213                 ............................ITVEMTKNIELIERLLS..N..LGIEHKQAVINRQNYEITLNKRhA.DGYRKFEILNRGIFRIVGYKVSEEIINNF.KTLGCEIKQG-PT.N.CYIDITA.NEHNIV------rlmes
K4FF15_9CAUD/106-208                 ............................ITSDMEEDKDFMLKLLD..E..NGFVLKKVETYRSNYLAILEKR.T.HGIRNFEINNNGNMRIFGYKMMEHHIQKF.TDIGMSCKIAKNG.N.VYLDIKR.SAENIEAVITVA.....
C4MZZ7_9CAUD/108-209                 ..........tpemvvladevkslledr-----------------..-..--IEIREIAENRSNLEVRFAKR.T.NGIRQIEVRRDGMMRIFGYNMTDKEKQVF.TSLNLDVKIKTGGkN.TYIDFQNvSSEVIKTV----tna..
A8R9P6_9CAUD/108-209                 ..........tpemvvladevkslledr-----------------..-..--IEIREIAENRSNIEVRFAKR.T.NGIRQIEVRRDGMMRIFGYNMTDKEKQVF.TSLNLDVKIKTGGkN.TYIDFQNvSSEVIKTV----tna..
Q19CD8_9CAUD/130-213                 ....................svsstsqa-----------------..-..--------VINRQNYEITLNNA.TrDGYRKFEILNRGIFRIVGYKVSEEIINNF.KTLGCEIKQG-PA.N.CYIDITA.NENNIV------rlmee
F2VXJ4_9CAUD/106-208                 ............................ITSDMEEDKDFMLKLLD..E..NGFVLKKVETYRSNYLAILEKR.T.HGIRNFEINNNGNMRIFGYKMMEHHIQKF.TDIGMSCKIAKNG.N.VYLDIKR.SAENIEAVITVA.....
E5EQ31_9CAUD/101-202                 ............................ITEDMISIKDFAVEYIE..G..K-VELKGTHEDRSNFLILFKKG.I.KGLGCIEIKNKPEIRVCIRKASKEAIELF.SSIGMKYRET-PA.Q.TYFDMPK.SHDNVKLLI---dtiv.
A0A023W6X3_9CAUD/105-209             ............................VTADMKATAESIKKRVE..E..LDVETKDIETYRSNLWVTLTKR.AkSGVRKFEVLNKGMFRIFGYKVRTELLDILkAECEATVKEATSG.N.CYIDMPL.TEDVINFVL---nid..
E1A172_9CAUD/112-213                 ............................ITVEMTKNIELVERLLS..N..LGIEHKQAVINRQNYEITLNKRhA.DGYRKFEILNRGIFRIVGYKVSEEIINNF.KTLGCEIKQG-PA.N.CYIDITA.NENNIV------rlmee
E5FJ40_9CAUD/101-201                 ............................VTDEMEATAEYIKEQLL..S..IGIDFKSISEDRSNLI-VKFKR.V.KTLKQIDVRRDGQIRVHAYNTEQKIVKQF.TDVGFSVKVG-GL.N.TYIDNHM.STENIQHVINI-l....
S5MLB3_9CAUD/106-208                 ............................ITSDMEEDKDFMLKLLD..E..NGFVLKKVETYRSNYLAILEKR.T.HGIRNFEINNNGNMRIFGYKMMEHHIQKF.TDIGMSCKIAKNG.N.VYLDIKR.SVENIEAVITVA.....
D9I6I5_9CAUD/92-187                  ...........................v-NSAQEEFKDYTLERVS..K..F-FEVKDVIIDRSNYLVRLKKR.T.KGVRQFECMHKGDFRIFAYQVPENMHRAL.IKAGMTFKRGASN.N.AYYDIKC.TNEN--------yf...
I3WVY4_9CAUD/99-202                  indemlemvsrtfamlennidtkpdyte-----------------..-..----------DRSNLFVHFTKR.L.KGIASIEIRNADLLRISIRKPEEGQVEYF.KTIGMVVHKVTPT.V.TYMDLPR.TMENLEILV---navi.
I7LHB8_9CAUD/117-218                 .............vtdtmqafaetiklg---------------LE..E..LDFDVKGIDENRSNLEVKINKC.S.HGIRQVEVRRADMIRIFGYNMSEEFAKKF.TDVGFTSKIGG-K.N.IYLDIAT.TSENIQTLISV-l....
Q6U967_9CAUD/111-212                 .................itaemtglmek-----------ISALV-..E..ENIGLKAVEIYRQNYQIIFSKR.TaEGYRKFEVLNNGKFRIFGYKVAEDKLEAF.RQVGAEIKVG-GS.N.TYIDIEQ.NEVNIAKVMQIA.....
E5EZ21_9CAUD/97-192                  .................eslaeqakeiv-----------------..E..SKFEVKEMVTYCSNFHIKLKKR.T.LGIRQFELTNSNKFRVFGYNMDDSIAKKL.ESLGAVVKKG-GS.N.IYLDFDL.SKEIIETVIN--sl...
G0X5A8_9CAUD/106-208                 ............................ITSDMEEDKDLMLKLLD..E..NGFVLKKVETYRSNYLAILEKR.T.HGIRNFEINNNGNMRIFGYKMMEHHIQKF.TDIGMSCKIAKNG.N.VYLDIKR.SVENIEAVITVA.....
J7KLW0_9CAUD/112-213                 ............................ITVEMTKNIELIERLLS..N..LGIEHKQAVINRQNYEITLNKRhA.DGYRKFEILNRGIFRIVGYKVSEEIINNF.KTLGCEIKQG-PA.N.CYIDITA.NENNIV------rlmee
D7RMQ7_9CAUD/132-234                 ...........vtpemvtladevkalle-----------------..-..DRIEIREIAENRSNLEVRFAKR.T.NGIRQIEVRRDGMMRIFGYNMTDKEKQVF.TSLNLDVKIKTGGkN.TYIDFQNvSSEVIKTV----tna..
C3V1W9_9CAUD/106-208                 ............................ITSDMEEDKDLMLKLLD..E..NGFVLKKVETYRSNYLAILEKR.T.HGIRNFEINNNGNMRIFGYKMMEHHIQKF.TDIGMSCKIAKNG.N.VYLDIKR.SAENIEAVIAVA.....
M1EAS7_9CAUD/107-211                 ............................ITGDMEADKDFMMELLG..TkeELFKIKKLDVYRSNFIAVLEKR.T.FGIRSFEVSNKGNFRISGYKMTEEQVKHF.EDLGMIAKHSKNG.N.VYLDIVR.TQENIETIIN--sv...
D4ZA65_BPAR1/106-208                 ............................ITSDMEEDKDFMLKLLD..E..NGFVLKKVETYRSNYLAILEKR.T.HGIRNFEINNNGNMRIFGYKMMEHHIQKF.TDIGMSCKIAKNG.N.VYLDIKR.SAENIEAVITVA.....
E3SF76_9CAUD/101-201                 ............................VTDEMEATAEYIKEQLL..S..IGIDFKSISEDRSNLI-VKFKR.V.KTLKQIDVRRDGQIRVHAYNTEQKIVKQF.TDVGFSVKVG-GL.N.TYIDNVM.STENIQHVINI-l....
C3V2P4_BPR51/106-208                 ............................ITSDMEEDKDFMLKLLD..E..NGFVLKKVETYRSNYLAILEKR.T.HGIRNFEINNNGNMRIFGYKMMEHHIQKF.TDIGMSCKIAKNG.N.VYLDIKR.SEENIEAVITVA.....
MOTA_BPT4/106-208                    ............................ITSDMEEDKDLMLKLLD..K..NGFVLKKVEIYRSNYLAILEKR.T.NGIRNFEINNNGNMRIFGYKMMEHHIQKF.TDIGMSCKIAKNG.N.VYLDIKR.SAENIEAVITVA.....
#=GR MOTA_BPT4/106-208         SS    ............................XXHHHHHHHHHHHHHHH..H..TT--EEEEEEETTEEEEEEEEE.E.TTEEEEEEETTSEEEEEEES--HHHHHHH.HHTT-EEEE-TTS.E.EEEEEE-.-HHHHHHHHHHH.....
#=GC SS_cons                         ............................XXHHHHHHHHHHHHHHH..H..TT--EEEEEEETTEEEEEEEEE.E.TTEEEEEEETTSEEEEEEES--HHHHHHH.HHTT-EEEE-TTS.E.EEEEEE-.-HHHHHHHHHHH.....
#=GC seq_cons                        ............................ITs-Mptst-hhhcLLs..c..pshtlKclph.RSNahslLpKR.T.cGIRpFEIpNsGphRIFGYKMtEcplppF.sslGhssKlupsG.N.sYlDIpp.opENIcsVIt.......
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