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Database: Pfam
Entry: MotCF
LinkDB: MotCF
Original site: MotCF 
#=GF ID   MotCF
#=GF AC   PF09158.5
#=GF DE   Bacteriophage T4 MotA, C-terminal
#=GF AU   Sammut SJ
#=GF SE   pdb_1kaf
#=GF GA   25.00 25.00;
#=GF TC   57.50 55.90;
#=GF NC   19.00 19.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   11918797
#=GF RT   The MotA transcription factor from bacteriophage T4 contains a
#=GF RT   novel DNA-binding domain: the 'double wing' motif. 
#=GF RA   Li N, Sickmier EA, Zhang R, Joachimiak A, White SW; 
#=GF RL   Mol Microbiol. 2002;43:1079-1088.
#=GF DR   INTERPRO; IPR015241;
#=GF DR   SCOP; 1kaf; fa;
#=GF CC   Members of this family adopt a compact alpha/beta structure
#=GF CC   comprising three alpha-helices and six beta-strands in the
#=GF CC   order: alpha1-beta1-beta2-beta3-beta4-alpha2-beta5-beta6-alpha3.
#=GF CC   The beta-strands form a single anti-parallel beta-sheet and the
#=GF CC   three alpha-helices pack side-by-side onto one surface of the
#=GF CC   beta-sheet. In this architecture, the domain's hydrophobic core
#=GF CC   is at the sheet-helix interface, and the second surface of the
#=GF CC   beta-sheet is completely exposed. The domain is a DNA-binding
#=GF CC   motif, with a consensus sequence containing nine base pairs
#=GF CC   (5'-TTTGCTTTA-3'), that appears to bind to various mot boxes,
#=GF CC   allowing access to the minor groove towards the 5'-end of this
#=GF CC   sequence and the major groove towards the 3'-end [1].
#=GF SQ   25
#=GS E5FJ40_9CAUD/101-201  AC E5FJ40.1
#=GS Q7Y4P8_BPR69/107-209  AC Q7Y4P8.1
#=GS Q56EC9_9CAUD/111-212  AC Q56EC9.1
#=GS A8R9P6_9CAUD/107-209  AC A8R9P6.1
#=GS Q06E72_BPR32/106-208  AC Q06E72.1
#=GS D9I6I5_9CAUD/92-187   AC D9I6I5.1
#=GS D9IEU6_BPT4/106-208   AC D9IEU6.1
#=GS Q6U967_9CAUD/111-212  AC Q6U967.1
#=GS G1FHI0_9CAUD/106-208  AC G1FHI0.1
#=GS E5E4L7_9CAUD/109-209  AC E5E4L7.1
#=GS G0X5A8_9CAUD/106-208  AC G0X5A8.1
#=GS G3MUJ6_9CAUD/37-139   AC G3MUJ6.1
#=GS E5DI00_9CAUD/107-211  AC E5DI00.1
#=GS E5EZ21_9CAUD/92-192   AC E5EZ21.1
#=GS D7RMQ7_9CAUD/132-234  AC D7RMQ7.1
#=GS C3V1W9_9CAUD/106-208  AC C3V1W9.1
#=GS C4MZZ7_9CAUD/107-209  AC C4MZZ7.1
#=GS D4ZA65_BPAR1/106-208  AC D4ZA65.1
#=GS E3SF76_9CAUD/101-201  AC E3SF76.1
#=GS E1A172_9CAUD/112-214  AC E1A172.1
#=GS F2VXJ4_9CAUD/106-208  AC F2VXJ4.1
#=GS E5EQ31_9CAUD/101-202  AC E5EQ31.1
#=GS C3V2P4_BPR51/106-208  AC C3V2P4.1
#=GS Q19CD8_9CAUD/112-214  AC Q19CD8.1
#=GS MOTA_BPT4/106-208     AC P22915.1
#=GS MOTA_BPT4/106-208     DR PDB; 1KAF B; 106-208;
#=GS MOTA_BPT4/106-208     DR PDB; 1KAF E; 109-208;
#=GS MOTA_BPT4/106-208     DR PDB; 1KAF F; 108-208;
#=GS MOTA_BPT4/106-208     DR PDB; 1KAF A; 106-208;
#=GS MOTA_BPT4/106-208     DR PDB; 1KAF C; 106-208;
#=GS MOTA_BPT4/106-208     DR PDB; 1KAF D; 108-208;
E5FJ40_9CAUD/101-201             ....VTDEMEATAEYIKEQL..LSIgID.FKSISEDRSNLIVKF-KRV.KTLKQIDVRRDGQIRVHAYNTEQKIVKQFTDVGFSVKV--GGLNTYIDNHMSTENIQHVINI-l..
Q7Y4P8_BPR69/107-209             ....VTPEMHELANFVFENI..KDK.VE.VKEIGENRSNLEVRFAKRV.LGIRQIEIRRDGALRIFAYNMSETESKLFTSLENDVKIKIGGKYTYIDFPNVSKEIITLVTNV...
Q56EC9_9CAUD/111-212             ....ITAEMTGLMEKISALV..EEN.IG.LKAVEIYRQNYQIIFSKRTaEGYRKFEVLNNGKFRIFGYKVAEDKLEAFRQVGAEIKV--GGSNTYIDIEQNEVNIAKVMQIA...
A8R9P6_9CAUD/107-209             ....VTPEMVVLADEVKSLL..EDR.IE.IREIAENRSNIEVRFAKRT.NGIRQIEVRRDGMMRIFGYNMTDKEKQVFTSLNLDVKIKTGGKNTYIDFQNVSSEVIKTVTNA...
Q06E72_BPR32/106-208             ....ITSDMEEDKDLMLKLL..DENgFV.LKKVETYRSNYLAILEKRT.HGIRNFEINNNGNMRIFGYKMMEHHIQKFTDIGMSCKIAKNG-NVYLDIKRSAENIEAVIAVA...
D9I6I5_9CAUD/92-187              ..vn--SAQEEFKDYTLERV..SKF.FE.VKDVIIDRSNYLVRLKKRT.KGVRQFECMHKGDFRIFAYQVPENMHRALIKAGMTFKR-GASNNAYYDIKCTNEN--------yf.
D9IEU6_BPT4/106-208              ....ITSDMEEDKDLMLKLL..DKNgFV.LKKVEIYRSNYLAILEKRT.NGIRNFEINNNGNMRIFGYKMMEHHIQKFTDIGMSCKIAKNG-NVYLDIKRSAENIEAVITVA...
Q6U967_9CAUD/111-212             ....ITAEMTGLMEKISALV..EEN.IG.LKAVEIYRQNYQIIFSKRTaEGYRKFEVLNNGKFRIFGYKVAEDKLEAFRQVGAEIKV--GGSNTYIDIEQNEVNIAKVMQIA...
G1FHI0_9CAUD/106-208             ....ITSDMEEDKDFMLKLL..DENgFV.LKKVETYRSNYLAILEKRT.HGIRNFEINNNGNMRIFGYKMMEHHIQKFTDIGMSCKIAKNG-NVYLDIKRSAENIEAVITVA...
E5E4L7_9CAUD/109-209             ihec----MEAFKDFALEYL..TDK.IE.VKNTVVDRSNFLILFAKRI.SSVGALEIKNKGEVRVVGRKPSDKVVEKLASIGMKYRQ--TPAQTYFDIECTEDNIVNIID--al.
G0X5A8_9CAUD/106-208             ....ITSDMEEDKDLMLKLL..DENgFV.LKKVETYRSNYLAILEKRT.HGIRNFEINNNGNMRIFGYKMMEHHIQKFTDIGMSCKIAKNG-NVYLDIKRSVENIEAVITVA...
G3MUJ6_9CAUD/37-139              ....VTPEMVTLADEVKALL..EDR.IE.IREIAENRSNLEVRFAKRT.NGIRQIEVRRDGMMRIFGYNMTDKEKQVFTSLNLDVKIKTGGKNTYIDFQNVSSEVIKTVTNA...
E5DI00_9CAUD/107-211             ....ITDQMEADKNLMMEILatKDNlFT.IKKLDVYRSNFIAVLEKRT.FGIRSFEVSNKGNFRISGYKMTEEQVKHFEDLGMVAKHSKNG-NVYLDIPRTQENIENIIHA-v..
E5EZ21_9CAUD/92-192              ....ISPELESLAEQAKEIV..ESK.FE.VKEMVTYCSNFHIKLKKRT.LGIRQFELTNSNKFRVFGYNMDDSIAKKLESLGAVVKK--GGSNIYLDFDLSKEIIETVIN--sl.
D7RMQ7_9CAUD/132-234             ....VTPEMVTLADEVKALL..EDR.IE.IREIAENRSNLEVRFAKRT.NGIRQIEVRRDGMMRIFGYNMTDKEKQVFTSLNLDVKIKTGGKNTYIDFQNVSSEVIKTVTNA...
C3V1W9_9CAUD/106-208             ....ITSDMEEDKDLMLKLL..DENgFV.LKKVETYRSNYLAILEKRT.HGIRNFEINNNGNMRIFGYKMMEHHIQKFTDIGMSCKIAKNG-NVYLDIKRSAENIEAVIAVA...
C4MZZ7_9CAUD/107-209             ....VTPEMVVLADEVKSLL..EDR.IE.IREIAENRSNLEVRFAKRT.NGIRQIEVRRDGMMRIFGYNMTDKEKQVFTSLNLDVKIKTGGKNTYIDFQNVSSEVIKTVTNA...
D4ZA65_BPAR1/106-208             ....ITSDMEEDKDFMLKLL..DENgFV.LKKVETYRSNYLAILEKRT.HGIRNFEINNNGNMRIFGYKMMEHHIQKFTDIGMSCKIAKNG-NVYLDIKRSAENIEAVITVA...
E3SF76_9CAUD/101-201             ....VTDEMEATAEYIKEQL..LSIgID.FKSISEDRSNLIVKF-KRV.KTLKQIDVRRDGQIRVHAYNTEQKIVKQFTDVGFSVKV--GGLNTYIDNVMSTENIQHVINI-l..
E1A172_9CAUD/112-214             ....ITVEMTKNIELVERLL..SNLgIE.HKQAVINRQNYEITLNKRHaDGYRKFEILNRGIFRIVGYKVSEEIINNFKTLGCEIKQ--GPANCYIDITANENNIVRLME--ei.
F2VXJ4_9CAUD/106-208             ....ITSDMEEDKDFMLKLL..DENgFV.LKKVETYRSNYLAILEKRT.HGIRNFEINNNGNMRIFGYKMMEHHIQKFTDIGMSCKIAKNG-NVYLDIKRSAENIEAVITVA...
E5EQ31_9CAUD/101-202             ....ITEDMISIKDFAVEYI..EGK.VE.LKGTHEDRSNFLILFKKGI.KGLGCIEIKNKPEIRVCIRKASKEAIELFSSIGMKYRE--TPAQTYFDMPKSHDNVKLLID--tiv
C3V2P4_BPR51/106-208             ....ITSDMEEDKDFMLKLL..DENgFV.LKKVETYRSNYLAILEKRT.HGIRNFEINNNGNMRIFGYKMMEHHIQKFTDIGMSCKIAKNG-NVYLDIKRSEENIEAVITVA...
Q19CD8_9CAUD/112-214             ....ITVEMTKISSLSSDCC..PTS.VSsTSQAVINRQNYEITLNNATrDGYRKFEILNRGIFRIVGYKVSEEIINNFKTLGCEIKQ--GPANCYIDITANENNIVRLME--ei.
MOTA_BPT4/106-208                ....ITSDMEEDKDLMLKLL..DKNgFV.LKKVEIYRSNYLAILEKRT.NGIRNFEINNNGNMRIFGYKMMEHHIQKFTDIGMSCKIAKNG-NVYLDIKRSAENIEAVITVA...
#=GR MOTA_BPT4/106-208     SS    ....XXHHHHHHHHHHHHHH..HHTT--.EEEEEEETTEEEEEEEEEE.TTEEEEEEETTSEEEEEEES--HHHHHHHHHTT-EEEE-TTS-EEEEEEE--HHHHHHHHHHH...
#=GC SS_cons                     ....XXHHHHHHHHHHHHHH..HHTT--.EEEEEEETTEEEEEEEEEE.TTEEEEEEETTSEEEEEEES--HHHHHHHHHTT-EEEE-TTS-EEEEEEE--HHHHHHHHHHH...
#=GC seq_cons                    ....ITs-MEp.tDhhhcLL..--p.hs.lKclpp.RSNallhhpKRT.cGIRpFElpNsGphRIFGYKMtE+clppFTslGhssKlttsG.NsYlDIcpos-NIttlIssA...
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