GenomeNet

Database: Pfam
Entry: MtrA
LinkDB: MtrA
Original site: MtrA 
#=GF ID   MtrA
#=GF AC   PF04208.11
#=GF DE   Tetrahydromethanopterin S-methyltransferase, subunit A 
#=GF AU   TIGRFAMs, Finn RD
#=GF SE   TIGRFAMs (release 2.0);
#=GF GA   25.00 25.00;
#=GF TC   26.10 30.60;
#=GF NC   20.00 19.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9559648
#=GF RT   Cloning, sequencing and expression of the genes encoding the
#=GF RT   sodium translocating N5-methyltetrahydromethanopterin : coenzyme
#=GF RT   M methyltransferase of the methylotrophic archaeon
#=GF RT   Methanosarcina mazei Go1. 
#=GF RA   Lienard T, Gottschalk G; 
#=GF RL   FEBS Lett 1998;425:204-208.
#=GF DR   INTERPRO; IPR030688;
#=GF DR   TC; 3.C.1;
#=GF CC   The N5-methyltetrahydromethanopterin: coenzyme M (EC:2.1.1.86)
#=GF CC   of Methanosarcina mazei Go1 is a membrane-associated, 
#=GF CC   corrinoid-containing protein that uses a transmethylation
#=GF CC   reaction to drive an energy-conserving sodium ion pump [1].
#=GF SQ   84
#=GS B8GF36_METPE/3-173       AC B8GF36.1
#=GS MTRA_METMS/4-176         AC D5E7Y7.1
#=GS C1F4T6_ACIC5/100-275     AC C1F4T6.1
#=GS MTRA_METST/4-176         AC Q2NI29.1
#=GS A2STR2_METLZ/4-175       AC A2STR2.1
#=GS MTRA1_METTH/4-176        AC O27227.3
#=GS D1YVZ3_METPS/4-174       AC D1YVZ3.1
#=GS A9A2W6_NITMS/13-155      AC A9A2W6.1
#=GS MTXA_METBF/1-167         AC O32854.1
#=GS F6BEA3_METIK/4-178       AC F6BEA3.1
#=GS L0HHV5_METFS/4-176       AC L0HHV5.1
#=GS MTRA_METMA/4-175         AC O59640.2
#=GS J9Z8W3_LEPFM/11-182      AC J9Z8W3.1
#=GS J1L1D4_9EURY/4-175       AC J1L1D4.1
#=GS B8GE98_METPE/4-176       AC B8GE98.1
#=GS L0L1I6_METHD/4-175       AC L0L1I6.1
#=GS D7E9H2_METEZ/4-170       AC D7E9H2.1
#=GS I0INS9_LEPFC/103-274     AC I0INS9.1
#=GS E1RDW7_METP4/4-175       AC E1RDW7.1
#=GS Q12VU8_METBU/4-176       AC Q12VU8.1
#=GS B8GEA0_METPE/4-175       AC B8GEA0.1
#=GS D5VQU3_METIM/4-177       AC D5VQU3.1
#=GS MTXA_METAC/1-167         AC Q8TPU9.1
#=GS A3CT39_METMJ/4-175       AC A3CT39.1
#=GS D7DUI1_METV3/4-177       AC D7DUI1.1
#=GS Q8PUT0_METMA/1-164       AC Q8PUT0.1
#=GS F6D2C8_METPW/4-176       AC F6D2C8.1
#=GS MTRA_METEZ/4-176         AC D7EBK7.1
#=GS Q2FRN1_METHJ/4-175       AC Q2FRN1.1
#=GS Q46FE9_METBF/1-162       AC Q46FE9.1
#=GS A0RXI7_CENSY/1-140       AC A0RXI7.1
#=GS U6E9X4_9EURY/3-175       AC U6E9X4.1
#=GS Q46BT7_METBF/1-166       AC Q46BT7.1
#=GS Q12TW9_METBU/4-135       AC Q12TW9.1
#=GS D1YWC8_METPS/5-159       AC D1YWC8.1
#=GS A0B8Y2_METTP/4-176       AC A0B8Y2.1
#=GS L0KYT2_METHD/8-174       AC L0KYT2.1
#=GS MTXA_METMA/1-142         AC Q8Q082.1
#=GS MTRA_METHJ/4-175         AC Q2FRN2.1
#=GS A2STR4_METLZ/4-175       AC A2STR4.1
#=GS MTRA_METV3/4-179         AC D7DUI0.1
#=GS D5E6K1_METMS/61-196      AC D5E6K1.1
#=GS MTRA_METBF/4-175         AC Q9Y8K4.1
#=GS D5E6K1_METMS/5-53        AC D5E6K1.1
#=GS K4MJD1_9EURY/10-177      AC K4MJD1.1
#=GS D5E9T3_METMS/2-157       AC D5E9T3.1
#=GS A6UWH8_META3/4-177       AC A6UWH8.1
#=GS MTRA_METJA/4-179         AC Q58261.2
#=GS A7I5S6_METB6/4-176       AC A7I5S6.1
#=GS R9SLV8_9EURY/4-176       AC R9SLV8.1
#=GS F7XQ94_METZD/4-175       AC F7XQ94.1
#=GS MTRA_METMP/4-178         AC Q6LWZ0.1
#=GS F6BEA2_METIK/4-179       AC F6BEA2.1
#=GS Q0W334_METAR/4-176       AC Q0W334.1
#=GS J1ANL9_9EURY/4-175       AC J1ANL9.1
#=GS Q0W333_METAR/4-176       AC Q0W333.1
#=GS A0A060HGZ4_9ARCH/21-158  AC A0A060HGZ4.1
#=GS A3CT41_METMJ/4-176       AC A3CT41.1
#=GS F4BZJ2_METCG/4-176       AC F4BZJ2.1
#=GS Q6LWY9_METMP/4-179       AC Q6LWY9.1
#=GS E3GZ46_METFV/4-175       AC E3GZ46.1
#=GS K4MGJ1_9EURY/4-175       AC K4MGJ1.1
#=GS MTRA_META3/4-177         AC A6UWH7.1
#=GS F0T8R8_METLA/4-176       AC F0T8R8.1
#=GS MTRA_METKA/4-181         AC O32867.3
#=GS E3GWY7_METFV/4-167       AC E3GWY7.1
#=GS A7I5S4_METB6/4-175       AC A7I5S4.1
#=GS K0IN48_NITGG/13-157      AC K0IN48.1
#=GS F7XKL5_METZD/1-167       AC F7XKL5.1
#=GS MTRA2_METRM/4-176        AC D3E0P6.1
#=GS E1RDW9_METP4/4-175       AC E1RDW9.1
#=GS H1YXH4_9EURY/4-175       AC H1YXH4.1
#=GS Q2W818_MAGSA/105-263     AC Q2W818.1
#=GS L0HFU1_METFS/4-175       AC L0HFU1.1
#=GS U6EEN6_9EURY/4-177       AC U6EEN6.1
#=GS MTRA_METAC/4-175         AC Q8TU03.1
#=GS G7WNE2_METH6/27-187      AC G7WNE2.1
#=GS F4C0Q4_METCG/15-179      AC F4C0Q4.1
#=GS Q47DR4_DECAR/95-263      AC Q47DR4.1
#=GS H1YXH2_9EURY/4-175       AC H1YXH2.1
#=GS MTRA2_METTH/7-180        AC O27134.1
#=GS MTRA1_METRM/4-176        AC D3E045.1
#=GS G7WPT7_METH6/4-176       AC G7WPT7.1
#=GS A5ULY7_METS3/4-174       AC A5ULY7.1
B8GF36_METPE/3-173                  .......kv--RPHPEYPPEEGRYLR..GNDFSPVAVAIVLN.....T...D...EDKiPpeiehLvrvgVET...G......AALSGTVQTPNIGFEKLIWNIVGNPNIRFLVLGGPESE...GHATGAALKELFKNGI...D...E...QSR.IVGSDAPFPFLYNIPRPVVNRFLDQV.TLVDC-QFQDAATIREAVRACFQEQPAVFR----------------gvmvg..................
MTRA_METMS/4-176                    .........KREPAAGWPILKGEYDV..GDPENCVAVITLGS.....H...L...DGG.P.....M....LEA...G......ASITGPCKTENLGLEKVVSHIIANPNIRYLVVTGSEVK...GHITGEAFIMLHKNGV...-...S...DNR.IVNASGAIPYVENLTEEAVQRYQEQI.ECIDLIGTEDMGTISSKIKELAAKDPDAFDADPLVIEVGGEAEEEEe......................
C1F4T6_ACIC5/100-275                ......dee----RAGWPPLPGDFKV..IRYGAPVAVCALNS.....T...E...LMK.T.....L....TEArpdG......LAIVGTMHTENLGIERVIRNTLANPNLRFLVICGTDTQqtvGHLPGQSLHSLFQNGL...D...E...KGR.IVGAKGKRPVLKNVTREEVQAFLAQV.EPVSMISEENPATVTEQITACARRDPGIYPWPAGTVSV--------erirar.................
MTRA_METST/4-176                    .........KKEVIQNWPLETGDYAV..GNVESPVAVVSLGS.....N...M...NDE.L.....V....-AA...G......AAISGPLHTENLGIEKVVANIISNSNIRYVLICGSEVQ...GHITGKTVEALYENGI...D...E...EKKsIIGSPGAIPFVENLPVEAVERFQKQV.SIVSMINNEDVSEISSKIDECISNDPGAYDEDAMIVEFNETPEEE-f......................
A2STR2_METLZ/4-175                  .........KKSPANGWPIIQGDYHT..GDANSPVAVITMGS.....H...L...DEA.G.....I....CAA...G......AALAGSCKTENLGIEKVVANVISNPNIRFVLLCGTEVK...GHLSGQSIEAMHKNGV...-...E...GGK.IVGSTGAIPFLENLTAEHIKRFQEQI.ELVNIMETEDMGQISAKINELKGRDPGAFAADPIVIQLTDDAGG--ae.....................
MTRA1_METTH/4-176                   .........KKSPAEGWPVVNGDYIV..GDPESPVAATTLAS.....H...I...EDV.P.....V....-EA...G......AAIAGPCKTENLGIEKMIANLISNPNIRFLILCGSEVQ...GHITGQSIEALHQNGV...D...P...DKRnIIGATGAIPYIENIPDEGIERFQKQL.EIVNLIDVEDADAIKAKVKECIEKDPGAFEEEAMVIKVEEGGEEEE.......................
D1YVZ3_METPS/4-174                  .........KKEPAKGWPVVKGEYDT..GDAKSPVAVATCGS.....H...F...NLF.P.....I....-KA...G......AAISGPFKTENLGIEKIVANVISNPNIRFLVICGSEVK...GHISGDALICLYKYGL...-...K...DGR.IVNAKGAIPFIENLDANAVKRFQEQV.QIFEMVDVEDEAKITQVIKDCLAKDPGAFAGEPMLITIKEKEEE--ve.....................
A9A2W6_NITMS/13-155                 ....kvvlp----------IKQEFYL..GNPNSQIAICTLASislldD...L...KDS.E.....L....-LS...K......VAIIGRLFSENKGIDSMIQYVYENKNITKIILCGKEVW...GHKSGHSLLQLHKNGI...D...K...NSR.IINSVSPDPYLT-VSKDMIEYFQKNI.SIVDLIDETNLEVISKK-----------------------------l......................
MTXA_METBF/1-167                    ........m-KKIAEAWPIVKGDYTV..GNPESRIAVVTLAS.....Q...I...NSL.P.....E....---...-......AALWGSSKTENLGVEKIIINTISNSNIRYILICGKESR...GHLAGHSLLAIHANGI...D...E...KGR.IVGSEGAIPFIENISREAVKRFQQQV.VLLDRIGLTNLEEIMKIVREYKDQ-GEVYPEEPLVA-I--------sqkkrqst...............
F6BEA3_METIK/4-178                  .........KKAPAAGWPIVSGEYVV..GNPESCVGVVTLGS.....H...G...LEQ.A.....C....IDA...G......AAIAGPCHTENLGIEKVVANYISNPNIRFMVLCGSEVQ...GHITGQCFKALWENGI...G...D...DGG.IIGAKGAIPFLENVGKDAVERFQRQIvEVVDLIDCEDVSKITAAIKECISKDPGAIDEEPMVLDLEGGGA---ggee...................
L0HHV5_METFS/4-176                  .........KKSPASGWPLIKGDFHS..GDANSPVAVITMGS.....H...L...DEQ.G.....I....CDA...G......AALCGSCKTENLGLEKVIANVIANPNIRFALLVGTEVK...GHLSAQTLVALHKNGV...-...K...DGR.VVGAEGAIPFIENLNDTHIKRFQEQV.EIVNIMETEDVGAVKAKINELKAKDPGAFAADPMVVEVKEAAGG--aee....................
MTRA_METMA/4-175                    .........KREPAPGWPILKGEYEV..GDVKNSVLVITCGS.....H...L...PGK.P.....I....LDA...G......AACTGSCKTENLGIEKVVAHIISNPNIRYLLVTGSEVK...GHITGQSMMSLHANGV...-...K...ENR.IAGALGAIPYVENLNAAAVARFQEQV.QVVNLLDTEDMGAITSKVRELASKDPGAFDADPLVVEISEEGEEEE.......................
J9Z8W3_LEPFM/11-182                 .......pk---AQEGWPPLPGDYRV..LRYQAPVAVCTLSD....iR...L...FET.L.....S....KSA...Gt....gLSIIGTLHTENLGIERIITNVLGNPHIRFLIVCGADSRqsvGHLPGQSLVSLMSAGL...D...E...KGK.INGALGKRPILKNIGRDAVEHFRNVI.TLLDMRGVENQDEILARIRECTTRNPGRSD----------------pfpslptiev.............
J1L1D4_9EURY/4-175                  .........KTSPASGWPIAKGDFHS..GDAKSCVAVVTMGS.....H...L...DEQ.G.....I....CDA...G......AALCGSCKTENLGLEKVIANIISNPNIRFVLTCGTEVK...GHLSGQTFQALHANGI...-...E...GGK.VVGSKGAIPFIENLDDAAIKRFQAQV.ELVDIMETEDLGAIKAKIAELAGKDPGAFGEAPMVVEVKEAEGG--ae.....................
B8GE98_METPE/4-176                  .........KKSPASGWPIVQGDFHS..GDANSPVAVITMGS.....H...L...DEQ.G.....I....CDA...G......AAICGSCKTENLGLEKVVANVISNPNIRFVLLCGTEVK...GHLSGQSLRQLHSSGV...-...D...KGK.IVGSEGAIPFIENLDDAAIKRFQEQI.EIVNIMESEDLGTIKAKINELKGKDPGAFAGDAMVVEVKEAGGA--aee....................
L0L1I6_METHD/4-175                  .........KREPAPQWPVLKGEYEV..GDVKNCVAVITLGS.....H...L...TGG.P.....Q....LDA...G......ACITGPCKTENLGIEKVVVHIISNPNIRFLIVTGSEVK...GHVTGDAILKMHQNGV...-...K...DNR.IVGAVGAIPYIENLTAEAIERFQQQV.ECVNFIGTEDTNAIVAKIKEYAAKDPGAYDAEPMLLKIGEGGEEE-k......................
D7E9H2_METEZ/4-170                  ........l-KRIADDWPVVKGDYTV..GNPESRIVVVTLAS.....S...I...ESN.P.....E....---...-......ACLWGTCKTENLGAEKLITNIVSNSNIRFVLLCGGESR...GHLSGHTILKLHKNGV...D...G...KGR.IIGSEGAIPFVENIPRIAIQRFRNQV.EVIDCIGETDSEVL-GNIVDTYKDKRDAYNEEPVLVTSKSRK----kkt....................
I0INS9_LEPFC/103-274                .......pk---AQEGWPPLPGDYRV..LRYQAPVAVCTLSD.....V...RlfeTLS.K.....S....VET...G......LSIIGTLHTENLGIERIITNVLGNPHIRFLIVCGADSRqsvGHLPGQSLVSLMSAGL...D...E...KGK.INGALGKRPILKNIGRDAVEHFRNVI.TLLDMQGVENQDEILARIRECTTRNPGRSD----------------pfpslptiev.............
E1RDW7_METP4/4-175                  .........KKSPASGWPKIQGDYHS..GDANSCVVVVTMGS.....H...L...DEQ.G.....V....CDA...G......AALCGSCKTENLGLEKIVANVVANPNIRFLITCGTEVK...GHLSGQCLKALHTGGV...-...E...GGK.IVGAKGAIPFIENLDDAAIKRFQEQV.EVIDIMETEDLGAIKAKVQDCISKDPGAFAGDAMVIEVKESEGG--se.....................
Q12VU8_METBU/4-176                  .........KREPAVDWPTLKGEYDV..GDVKNCVAVITCGS.....H...I...PSG.P.....Q....LEA...G......AAITGPCKTENLGLEKVVAQIIGNPNIRFVIITGSEVK...GHITGEAFIMVHKNGV...-...S...DNR.IVGATGAIPYVENLTDAAVERLQQQV.EMINMIGTEDMGQIVAKIKECVAKDPGALDVDPMVVEVGEAGGE--gee....................
B8GEA0_METPE/4-175                  .........KKSPASGWPIVQGDFHS..GDANSPVAVITMGS.....H...L...DEQ.G.....I....CDA...G......AAICGSCKTENLGLEKVVANVISNPNIRFVLLCGTEVK...GHLSGQSLRQLHSSGV...-...D...KGK.IVGSEGAIPFIENLDDAAIKRFQEQI.EIVNIMESEDLGTIKAKINELKGKDPGAFAADAMVVEVKEAGGS--te.....................
D5VQU3_METIM/4-177                  .........KKEPAPGWPIVSGEYVV..GNPESCVGVVTLGS.....H...G...LEQ.A.....C....IEA...G......AAIAGPCHTENLGIEKVVANYISNPNIRFMILCGSEVQ...GHITGQCFKALWENGI...D...D...SGQ.IIGAKGAIPFLENVDKDAVERFRRQIvEVIDLIDCEDIGKITQAIKECLSKDPGAIDEDPYIIQLEGGGGEE-e......................
MTXA_METAC/1-167                    ........m-KTIAENWPPVRGDYVT..GKPDSRIAVVTLAS.....H...L...EAF.P.....N....---...-......AAIWGSSKTENLGVEKIIVNVISNSNIRYVLVCGTESR...GHLAGHSLLAIHANGI...D...E...KGR.IVGSQGAIPFIENISREAVDRFQRQV.TLLDRIGLNDPEEIRKIVEDYRDKG-EVYPEEPVVVCA--------pkkrqas................
A3CT39_METMJ/4-175                  .........KKSPASGWPIVQGDFHT..GDAQSCVGVVTMGS.....H...L...DEQ.G.....I....CDA...G......AAIAGSCKTENLGLEKIIANVISNPNIRFILCCGTEVK...GHLSGQSFIALHEGGV...-...S...GGK.IVGAQGAIPFIENLSDDAISRFQEQI.EIVNIMESEDMGAIKAKIDELKARDPGAFGAEPMIVEVKEAGGA--ae.....................
D7DUI1_METV3/4-177                  .........KKAPATGWPVANGEYVV..GNPESCVAVVTLGS.....H...G...LDE.A.....A....IEA...G......AAISGPCHTENLGIEKVIVNYISNPNIRFMVVTGSEVQ...GHITGQCFKALYENGI...G...D...DGG.IIGAKGAIPFMENVGQEPVARFQNQIvELIDMIDSEDKGKIQQTVKDCISKDPGASEEDAMVIDLEGKAGE--ag.....................
Q8PUT0_METMA/1-164                  ........m------GWPVISGDYIV..GDPKSPVAVVTLAS.....D...Y...QSL.N.....L....--K...N......YAICGTCFTENFGIEKVIVNVLSNPRISCLVVCGQES-...DHFAGQSLLALAENGV...S...AfggSKR.IIGSEGVIPYLDDIPATAISRFLREI.EVIDLVGTTDPAVIQQAIDSCSGKERGEA-----------------pelsmpeinehsw..........
F6D2C8_METPW/4-176                  .........KKAASEGWPPVTGDYEV..GDVESPVGVVTLGS.....H...M...ADM.P.....I....-QA...G......AAISGPLHTENLGMEKVIANIISNPNIRFLLVTGSEVQ...GHITGATMRALMDNGV...D...P...EKRnIIDAPGAIPYIENIPDEGIDRFRNQL.ELVEMIDVEDPAAISSKIKECIEKDPGAFEEEAMVIEVEEEGEEEE.......................
MTRA_METEZ/4-176                    .........KKEPAEGWPILKGEYEV..GDPNNCVAVITCGS.....H...L...EGQ.P.....M....LDA...G......ASIVGPCKTENLGLEKVVSHIISNPNIRYLIVTGAEVK...GHITGEAMMMLHKNGV...-...K...DNR.IVGATGAIPYVENLTEESVERLQQQLeECVDLLGTEDLNTITSKIKELAEKDPGAFDAEPMIIQLEEEEEEEE.......................
Q2FRN1_METHJ/4-175                  .........KGEAASGWPIVQGDFHT..GDSKSPVAVVTMGS.....H...L...DEG.A.....I....CSA...G......AAIAGSCKTENLGLEKVIANVISNPNIRFVITCGTEVK...GHLSGQSLIALHQNGV...-...D...GGK.IVGSKGAIPFIENLTGDHIKRFQEQV.EIVDIMESEDIGAISAKINELKARDPGVFPGGPMVVEIKEEGG---ggg....................
Q46FE9_METBF/1-162                  ........m------EWPITSGNYVV..GDTNSSVAVVTLAS.....D...Y...KEW.G.....L....--K...N......YAICGTCFTANFGIEKIITNVLANPNINYLVVCGKES-...AHWAGQSLVSLAENGV...S...TmagSRK.IIGSKSPLSYLNEIPMTAISRFIKEI.KIIDLIGNKDPDAIQKAIDSCTGQK---------------------rseayivsmpeidgs........
A0RXI7_CENSY/1-140                  ........m-----------RGTVHL..GNPESTVAVCTLSS.....M...D...LLD.R.....I....--A...GselmeeIALAGRLLSENEGIDALIRSA-NSGNIRTVVLCGREVR...GHLAGHSLLELHKNGI...G...P...GGR.IAGSASPHPVLESG-QAEVDLFRGRV.DIIDAIGETGLDDIGR------------------------------lvrsa..................
U6E9X4_9EURY/3-175                  ........g-KKSVQEWPPVVGDYTI..GDVESAVAVVTLGS.....H...M...EDI.P.....V....-NA...G......ASISGPLHTENLGIEKVIANVVSNPNLRFLVVCGAEVQ...GHITGQSIKALHENGA...D...P...EKKrINGATGAIPYVENLNEEAIQRFQDQV.EVIDMVNVEDPHQIQAQIKECLAQDSGAFEEESLVIQLPKKGA---hpt....................
Q46BT7_METBF/1-166                  ........m------AWPITSGDYIV..GDPKSPVAVVTLAS.....D...Y...RNL.N.....L....--K...N......YAICGTCFTENFGIEKIIVNVLSNPRISCLIVCGKES-...EHFAGQSLLSLAENGV...S...TfggSKK.IIGSEGVIPYLNEIPATAISRFLREI.EVIDLVGITDPSVIQQAIDSCSRKER--------------------seapelfmpeidenswkk.....
Q12TW9_METBU/4-135                  ......yek-----------------..--------------.....-...-...---.-.....-....---...-......AAMWGSCKTENLGAEKIIINTISNSNIRYVLLCGNESK...GHLAGQTLIALHKNGI...D...N...DGR.IIGSDGAIPFVENIGKDAIERFQKQV.TIIDHIGLTDLDEIYNIVDEYSSKGS-PYSEGPFVVEVVTK-----rktv...................
D1YWC8_METPS/5-159                  ......gdk----------IEKTYKY..GDASSPVAVATLAS.....D...Y...EKF.D.....L....--K...G......YAILGSVFTENFGVQMAIANMLKDQNIGYLILCGQES-...AHLSGHAFVTLHENGVvqiG...T...SRR.IIGCKSPLPFIDEIPMGAIDEYQENI.KLIDMIGIEDTKLIQAKIDECTEE----------------------skkrsyrrkpf............
A0B8Y2_METTP/4-176                  .........KKKPAEPWPVITGEYEV..GNPESPVAVVTCGS.....H...L...NNA.E.....L....VAA...G......AALAGPCKTENIGIEKMVANVISNPNIRYLIITGMEVK...GHITGQAIEAFTASGI...D...K...EGR.IVGAKGAIPFIQNLTPEAIERWRQQI.TTINMIDTEDMGAITAKIKELVAKDPGALDVEPMIVEIKEGAGEE-g......................
L0KYT2_METHD/8-174                  .....sidm-----NGWPLTDGDYVI..GDPDSPVAVVTLAS.....D...Y...KKL.G.....L....--H...N......YAICGTCFTENFGIQKVIVNILSNPKISCLIVCGKES-...SHFAGQSILALVENGV...S...TlggYKK.IIGSNGVIPYLDEIPLAAINRFIREI.EVIDLIGTTDQEIIQEAIDSYRGKE---------------------rseapkylmseidens.......
MTXA_METMA/1-142                    ........m-----------------..---------VTLAS.....H...L...DAC.P.....D....---...-......AAIWGSSKTENLGVEKIIVNVISNSNIRYVLVCGTESR...GHLAGHSLLAIHANGI...D...E...QGR.ITGSQGAIPFIENISGTAVERFQQQV.TVLNRIGLNDPEEIRRIVEDYRDK-GEAYPEEPMLVCAP-------kkrqts.................
MTRA_METHJ/4-175                    .........KKSPASGWPIVQGDFHT..GDPNSPVAVVTMGS.....H...L...DEG.A.....I....CSA...G......AAIAGSCKTENLGLEKVIANVISNPNIRFVITCGTEVK...GHLSGQSLIALHQNGV...-...D...GGK.IVGSKGAIPFIENLSADNIKRFQEQV.ELVDIMESEDLGAISAKIKELTARDPGAFDAEAMIVEIKEEGGG--aa.....................
A2STR4_METLZ/4-175                  .........KKSPAGGWPIIQGDYHT..GDANSPVAVITMGS.....H...L...DET.A.....I....CVA...G......AALAGSCKTENLGIEKIVANVISNPNIRFVLLCGTEVK...GHLSGQSIEAMHKNGV...-...E...GGK.IVGSTGAIPFLENLGDSDIKRFQEQV.ELINIMETEDLNVIAAKINELKARDPGAFGADPVVIQLSDDDS---sgg....................
MTRA_METV3/4-179                    .........KKAPATGWPVANGEYVV..GNPESCVAVVTLGS.....H...G...LDE.A.....A....IEA...G......AAISGPCHTENLGIEKVIVNYISNPNIRFMVVTGSEVQ...GHITGQCFKALYENGI...G...D...DGG.IIGAKGAIPFMENVGQEPVARFQNQIvELIDMIDSEDKGKIQQTVKDCISKDPGAFEEDAMVIDLEGKAG---gagee..................
D5E6K1_METMS/61-196                 gykkpclqn-----------------..--------------.....-...-...---.-.....-....---...-......YAICGTCFTENFGIQKVIANILSNPKINCLIVCGKESK...-HFAGQSIIALVENGV...StmaD...YKK.IIGSKGVIPYLDEIPMTAINHFLKEI.EVIDLIDTTDPETIQKVIDSCKLKERS-------------------eakkypipqiden..........
MTRA_METBF/4-175                    .........KKEPAPGWPILKGEYEV..GDVKNCVLVITCGS.....H...L...PGQ.P.....I....LDA...G......AAVTGSCKTENLGIEKVVAHIISNPNIRYLLVTGSEVK...GHITGQSVMSLHANGV...-...K...DNR.ISGALGAIPYVENLNEDAIARFQEQV.DVVNLLDTEDMGAITSKVKELASKDPGAFDAEPMIVEISEEGEEEE.......................
D5E6K1_METMS/5-53                   ......kst---DPNNWPMEEGDYVI..GDPDSPVAVVTLTS.....D...Y...RNM.D.....C....I--...-......--------------------------------------...----------------...-...-...---.--------------------------.----------------------------------------------hdpcedgtpq.............
K4MJD1_9EURY/10-177                 ......skd----ISGWPVTDGDYVI..GDPDSPVAVVTLAS.....D...Y...EKL.G.....L....--Q...N......YAICGTCFTENFGIQKVIVNVLSNPRINCLIVCGKESK...-HFAGQSIMALVENGV...StmgD...YKK.IIGSKGVIPYLDEIPMTAINRFVREI.EIVDLIDITDLETIQRAIDSCKGKERSEAST---------------ypmpeidensw............
D5E9T3_METMS/2-157                  .......dt---VSEKWPVTKGDFSA..GNTKSCIAVVTLAS.....S...M...PLF.E.....K....---...-......AAIWGSCKTENLGAEKVVMNVVSNCNIRYVLLCGGESR...GHLAGQTLKALYENGI...D...E...DGR.ILGSEGAIPFIENLEIETIQRFRQQV.ELIDRIGLTDLDEICSIVDNYHD-----------------------sekpfeafpvs............
A6UWH8_META3/4-177                  .........KKAPASGWPIVSGEYVV..GNPESCVAVVTLGS.....H...G...LDE.A.....A....IEA...G......AAISGPCHTENLGIEKVVANYISNPNIRFMLVTGSEVQ...GHITGQCFKALYENGI...G...D...DGG.IIGAKGAIPFLENAGQDAISRFQNQLvEIVDLIDVEDTGKISSVIKDCISKDPGAFEEDPMILDLEGGGGE--ag.....................
MTRA_METJA/4-179                    .........KREPAPGWPIVSGEYVV..GNPESCVGVVTLGS.....H...G...LEQ.A.....C....IDA...G......AAIAGPCHTENLGIEKVVANYISNPNIRFMILCGSEVQ...GHITGQCFKALWENGI...G...D...DGG.IIGAKGAIPFLENVNKEAVERFRRQIvEVVDLIDCEDIGKITQAIKECLSKDPGAIDEDPFIIELEGGKG---ggeee..................
A7I5S6_METB6/4-176                  .........KKSPASGWPLVKGDFHS..GDANSPVAVITMGS.....H...L...DEQ.G.....I....CDA...G......AAMCGSCKTENLGLEKVIANYIANPNIRFVLLCGTEVK...GHLSAQSLIALHKGGV...-...K...DGR.IVGAEGAIPFIENLNDAAIKRFQEQV.SIVNIMETEDLNAIKAKINELKAKDPGAFAADPLVVEVKEAAA---ggge...................
R9SLV8_9EURY/4-176                  .........KKSPADGWPLISGEYEV..GDPESPVAATTLAS.....E...L...AGD.I.....V....-GA...G......AAIAGTCHTENLGVEKVVANTISNPNIRFLIVCGAEVQ...GHITGQCFEALHANGC...D...P...EKKkVNGAIGAIPFVDNLPLEAVERFQNQV.ELISMIDNEDVGAITAKVKECIEKDPGAIEEEAMVIDVSEGGEAE-e......................
F7XQ94_METZD/4-175                  .........KREPAPEWPILKGEYDI..GDVKNCVAVITLGS.....H...L...PAE.P.....Q....LEA...G......AAITGPCKTENLGLEKVLAHIISNPNIRYLLITGSEVK...GHITGDAFLKIHQNGV...-...K...ENR.IVGAVGAIPYVENLTPEAIERFQQQI.ECVDLIGTENMSEITSKIKELASRDPDAFDADPMVVKVGEDGAEEE.......................
MTRA_METMP/4-178                    .........KKAPAAGWPVANGEYVV..GNPESCVAVVTLGS.....H...G...LDQ.A.....A....IDA...G......AAISGPCHTENLGIEKVVANYISNPNIRFMVITGSEVQ...GHITGQCIKALYENGI...G...D...DGG.IIGAKGAIPFMENVGTEPVGRLQSQIvECIDLIDVEDTGKISDAIKNCISKDPGAFEEEPMVIELEGGA----aaage..................
F6BEA2_METIK/4-179                  .........KKAPAAGWPIVSGEYVV..GNPESCVGVVTLGS.....H...G...LEQ.A.....C....IDA...G......AAIAGPCHTENLGIEKVVANYISNPNIRFMVLCGSEVQ...GHITGQCFKALWENGI...G...D...DGG.IIGAKGAIPFLENVGKDAVERFQRQIvEVVDLIDCEDVSKITAAIKECISKDPGAIDEEPMVLDLEGGGA---ggeee..................
Q0W334_METAR/4-176                  .........KKEPAKGWPVIKGEFDV..GDPKSCVAVATAGS.....H...F...GQW.P.....I....-KA...G......AAISGPFHTENLGIEKIVANVISNPNIRFIIITGAEVK...GHISGDALECLHKNGL...-...K...GGR.IVGAKGAIPFIENLDDKAVKRFQEQV.QTVYMIDVEDEQKITAAIKDCIAKDPGAFAGEPMLLEIKETKIGE-eee....................
J1ANL9_9EURY/4-175                  .........KKSPASGWPIAKGDFHS..GDANSCVAVVTMGS.....H...L...DEQ.G.....I....CDA...G......AALCGSCKTENLGLEKVIANIISNPNIRFVLTCGTEVK...GHLSGQTFQALHANGV...-...E...GGK.VVGSKGAIPFIENLDDAAIKRFQAQV.EVVDIMETEDLGAIKAKIAELTGKDPGAFGEAPMVVEVKEAEGG--aa.....................
Q0W333_METAR/4-176                  .........KKEPAKGWPVIKGEFDV..GDPKSCVAVATAGS.....H...F...GQW.P.....I....-KA...G......AAISGPFHTENLGIEKIVANVISNPNIRFIIITGAEVK...GHISGDALECLHKNGL...-...K...GGR.IVGAKGAIPFIENLDDKAVKRFQEQV.QTVYMIDVEDEQKITAAIKDCIAKDPGAFAGEPMLLEIKETKIGE-eee....................
A0A060HGZ4_9ARCH/21-158             vrhesfggr-----------------..---GREVAVCTLGSidlleR...I...SKS.E.....I....IMD...R......VAIAGRLLSENKGIDAIIDYVSAHPDLKRIVVCGREVK...GHMAGQALLALYKNGI...D...G...QGR.IIGAAGPYPILL-SPREKVEAFRRQV.AIADMTGITDLEKIM-------------------------------pll....................
A3CT41_METMJ/4-176                  .........KKSPASGWPIVQGDFHT..GDAQSCVGVVTMGS.....H...L...DEQ.G.....I....CDA...G......AAIAGSCKTENLGLEKIIANVISNPNIRFILCCGTEVK...GHLSGQSFIALHEGGV...-...S...GGK.IVGAQGAIPFIENLSDDAISRFQEQI.EIVNIMESEDMGAIKAKIDELKARDPGAFGAEPMIVEVKEAGGA--aee....................
F4BZJ2_METCG/4-176                  .........KKKPSDPWPTITGEYEV..GNPESPVAVCTCGS.....H...L...HNA.D.....L....IKA...G......AALAGPCKTENIGIEKMVANVISNPNIRFVLVTGMEVK...GHITGQAVEAFTQSGI...D...K...EGR.IIGAKGAIPFIQNLTPEAIERWKNQV.EAVMMLNTEDIGAIAGKVKELASKDPGALDVEPMAIEIKEGGEEEE.......................
Q6LWY9_METMP/4-179                  .........KKAPAAGWPVANGEYVV..GNPESCVAVVTLGS.....H...G...LDQ.A.....A....IDA...G......AAISGPCHTENLGIEKVVANYISNPNIRFMVITGSEVQ...GHITGQCIKALYENGI...G...D...DGG.IIGAKGAIPFMENVGTEPVGRLQSQIvECIDLIDVEDTGKISDAIKNCISKDPGAFEEEPMVIELEGGA----aaagee.................
E3GZ46_METFV/4-175                  .........KKEPAEGWPVVSGDYIV..GDPESPVAAVTLAS.....H...I...EDI.P.....I....-DA...G......AAIAGPCKTENLGIEKVIANIISNPNIRFLVLCGSEVQ...GHITGQSIKALHKNGV...D...D...KKK.IIGAKGAIPYIENLPEEALERFQKQV.EIVDLIDVEDADQIKEKVKECIEKDPGAFEEEAMVVKVEEEEEEG-e......................
K4MGJ1_9EURY/4-175                  .........KREAAPDWPILKGEYDV..GNIKNCVAVITCGS.....H...L...ASG.A.....Q....LEA...G......AAITGPCKTENLGIEKVVAHIISNPNIRYLIVTGAEVK...GHITGQAMLALHRGGV...-...K...DNR.IVGATGAIPYIENLTEAIIKRFQEQV.ECIDFIGTEDMNAIVAKIKEYAAKDPGAFDADPMVVEVGGGSEEE-g......................
MTRA_META3/4-177                    .........KKAPASGWPIVSGEYVV..GNPESCVAVVTLGS.....H...G...LDE.A.....A....IEA...G......AAISGPCHTENLGIEKVVANYISNPNIRFMLVTGSEVQ...GHITGQCFKALYENGI...G...D...DGG.IIGAKGAIPFLENAGQDAISRFQNQLvEIVDLIDVEDTGKISSAIKDCISKDPGAFEEDPMILDLEGGGGE--ag.....................
F0T8R8_METLA/4-176                  .........KKSPAEGWPVINGDYVT..GDPESPVAVATLAS.....H...N...EQI.P.....V....-DA...G......AAIAGPCKTENLGIEKMISNLISNPNLRFLILCGAEVQ...GHITGESIKALHENGV...D...P...EKRsIVGAPGAIPYIENVPDAGLDRFRSQF.EIVDLIDVEDAAAIQAKVKECIEKDPGAIEEEAMVIEIEEEGEEEE.......................
MTRA_METKA/4-181                    .........KAEPAEGWPVVEGDYVV..GDPEAPVHVVTLGS.....H...I...EED.I.....L....KAA...Ge...dkVAIAGPCKTENIGIEKVIANVIANPNIRFGVLCGAEVT...GHLTGQCFKAMYENGV...D...P...DSGeIIGAEGAIPYLENIPEEAVERYRDQIvELVDLIDVEDVDEIVKAIEECVEKDPGAYEEGPMTISLEEEEEEE-l......................
E3GWY7_METFV/4-167                  .........KKEPAEGWPVVSGDYIV..GDPESPVAAVTLAS.....H...I...EDI.P.....I....-DA...G......AAIAGPCKTENLGIEKVIANIISNPNIRFLVLCGSEVQ...GHIVGQSMKALHKNGV...D...D...KRK.IIGAKGAIPYIENLPEEALERFQKQV.EIVDLIDVEDADQIKEKVKECIEKDPGAFEEEEVILR---------l......................
A7I5S4_METB6/4-175                  .........KKSPATGWPLVKGDFHS..GDANSPVAVITMGS.....H...L...DEQ.G.....I....CDA...G......AAMCGSCKTENLGLEKVIANYIANPNIRFVLLCGTEVK...GHLSAQSLVALHKGGV...-...K...DGR.IVGAEGAIPFIENLNDAAIKRFQEQV.SIVNIMETEDLNAIKAKINELKAKDPGAFAADPLVVEVKEAAA---gga....................
K0IN48_NITGG/13-157                 .kvceavlp----------IKHEYHL..GMGKE-LAICTLSSmdlleK...L...SKS.D.....P....VMN...K......IAIAGRLLSENRGIDAMIKFALDHPELRRIIVCGKEVK...GHRAGQALLALARNGI...D...R...NGR.IVGALGPYPILES-PAGDVDAFRQQV.EILDMIGTTDIEKL--------------------------------lva....................
F7XKL5_METZD/1-167                  .......me--HVANDWPPAKGDYVI..GSIDSRIAVVTLAS.....S...I...EPT.E.....K....---...-......AAIWGTCKTENLGVEKVVINIISNSNIRYLLLCGGESR...GHLSGKSLIALHNNGI...D...E...NGR.IIGSDGAIPFIENIPENAIIRFQEQV.DLIDYTGLTDKKEIYELVD-VYSNKNEAYAEEPFVILTGK------rkksc..................
MTRA2_METRM/4-176                   .........KKPTAENWPVVSGDYIV..GDPESPVAVTTLAS.....H...N...EDI.P.....A....-AA...G......AAIAGPCKTENLGIEKVVANIISNPNIRFLILCGAEVQ...GHITGQSFKALYENGC...D...P...EKKkITGATGAIPFVENIPMEGVERFQQQL.ELVDMIDNEDGGAITAKVKECIEKDPGAFEEDSLVIKIDEER----yskk...................
E1RDW9_METP4/4-175                  .........KKSPASGWPKIQGDYHT..GDANSCVVVVTMGS.....H...L...DEQ.G.....V....CDA...G......AAMCGSCKTENLGLEKIVANVISNPNIRFLITCGTEVK...GHLSGQCLKALHAGGV...-...E...GGK.IVGAKGAIPFIENLNDAAIKRFQEQV.ELIDIMETEDLGAIKAKVQECISKDPGAFEGDAMVIEVKEEEGG--ag.....................
H1YXH4_9EURY/4-175                  .........KRAPASGWPKIQGDYHA..GNAESPVAVVTVGS.....H...L...DEQ.G.....I....CDA...G......AAICGSCKTENLGLEKIVANVVANPNIRFMVTCGTEVK...GHLSGQCLHALHANGL...-...E...GGK.IVGAKGAIPFIENLTDESIQRFRDQI.EMVDIMESEDMGAIKAKIDELTARDPGAFDGEPIVLEVKEDDGG--aa.....................
Q2W818_MAGSA/105-263                ......fei----REGWPPVPGDYFVlcHGADCTVAVSTLGD.....V...A...LAA.R.....I....ADL...Kp...paLCMVGKTETENIGIDKVVRNVAANPDITTLILVGQDPP...GHQPGRTLLALAENGV...D...E...AMR.VIGSPGKRPILRNVTPDEVATFRQRV.QIIDLIGEIDPGRIIAAIEQH-------------------------ntpapqk................
L0HFU1_METFS/4-175                  .........KKSPASGWPLIKGDFHS..GDANSSVAVITMGS.....H...L...DEQ.G.....I....CDA...G......AALCGSCKTENLGLEKVIANVIANPNIRFALLVGTEVK...GHLSAQTLVALHKNGV...-...K...DGR.VVGAEGAIPFIENLNDTHIKRFQEQV.EIVNIMETEDVGAVKAKINELKAKDPGAFAADPMVVEVKEAAGG--qe.....................
U6EEN6_9EURY/4-177                  .........KKSPAEGWPVINGDYVV..GDPESPVAATTLAS.....H...I...EQI.A.....V....-DA...G......AAISGPCKTENLGIEKMIANLISNPNIRFLILTGSEVQ...GHITGQSIESLHKNGV...D...P...EKRkIVGATGAIPFIENIPDEGIERFQQQM.EIVSIIDVEDAATIQSKVKECIDKDPGAFEEEAMVIKVEEGEGDE-ee.....................
MTRA_METAC/4-175                    .........KKEPASGWPILKGEYEV..GDVKGCVAVITCAS.....H...L...PGK.P.....V....LDA...G......AAITGSCKTENLGIEKVVAHVISNPNIRYLVVTGAEVK...GHVTGQAMLSIHANGV...-...K...EHR.IVGAVGAIPYVENLNDDAVARFQQQI.ETVNLLDTEDMGAITAKVRELVAKDPGAFDAEPMVVEISEEGEEEE.......................
G7WNE2_METH6/27-187                 ......rad---EAGRWPPLRGEYSL..GDPGSRIAVVTLAS.....S...L...R--.-.....-....-AP...G......AAIWGPCKTENLGVEKVVGNLISNSEIRFLLVCGEESK...GHLPGDSIVALHRNGI...D...K...DGR.IVGSRGAIPFIENLSPEAIDRFQRQV.EVIDRIGLVDEDEIERIVREHR------------------------slsepfpeppmevvkrr......
F4C0Q4_METCG/15-179                 .....qgyl-----DPWPPVRGEYRL..GDPRAGVAVVTLAS.....V...F...NPR.-.....-....---...G......TAISGPCKTENLGLEKIVANVISNSNIRFLIVCGVESK...GHLPGNTLLALHKNGI...D...E...KGR.IIGSKGAIPFIQNLSVQAVERFQRQV.ELIDRIGLEDMKEIEKLVSQY-------------------------nhlampfpeepyqvikrkaarqe
Q47DR4_DECAR/95-263                 .....epqe----REGWPPLPGDYHV..VRYQAPVAVCTLNS.....DdlvV...RLT.A.....T....QAP...G......LAVVGSLHTENLGIEHLIRNLLPNPHIRFLIVCGEDTRkaiGHLPGQSLVALMRNGL...E...D...GGR.IRGAEGKRPVIKNVPPEHVEAFRRQV.QVVDCIGMTDLEGIAAEIARAAADDPGP------------------apeiftdl...............
H1YXH2_9EURY/4-175                  .........KKSPASGWPKIQGDYHA..GDAESPVVVVTVGS.....H...L...DEQ.A.....V....CDA...G......AAMCGSCKTENLGLEKIVANVIANPNIRFIITCGTEVK...GHLSGQCLIALHANGL...-...E...GGK.IVGAKGAIPFIENLTDEGVQRFREQV.EIVDIMESEDMGTIKAKIEELKGRDPGAFDGDPIVIEVKEDGA---ggd....................
MTRA2_METTH/7-180                   .........KKPVPEDWPHIVGDYVV..GDEESPVAVVTLGS.....H...M...EDE.P.....V....-KA...G......AAISGPLHTENLGIEKVVGNVIANPNLRFLVVCGAEVM...GHITGQTMKALHSNGV...D...L...ETGrIIGATGAIPYIENMPEEAIERFRRQV.ELVDMVDVEDPDSIAARIQECVVHDSGAMEEEPLILKVPEIGKG--dse....................
MTRA1_METRM/4-176                   .........KKPAADNWPVVSGDYIV..GDPESPVAVTTLAS.....H...N...EDI.P.....A....-AA...G......AAIAGPCKTENLGIEKVVANIISNPNIRFLILCGAEVQ...GHITGQSIQALHENGC...D...P...EKKkITGATGAIPFVENIPMEGVERFQQQV.ELVDLIDNEDGGAITAKVKECIEKDPGAFEEDAMVIEVKEGDDDE-d......................
G7WPT7_METH6/4-176                  .........KKPTSDPWPWLTGEYVV..GNPESPVAVVTCGS.....H...L...NNA.P.....F....IDA...G......SALAGPCKTENIGIEKMVANIISNPNIRFLIITGMEVK...GHITGQAIEAFAANGI...D...Q...EGR.IVGATGAIPFIQNLTPEAIERFKQQI.TTINIIDTEDTGTIVSKIKECVSKDPGALDVEPMAVEISEGEAEEE.......................
A5ULY7_METS3/4-174                  .........KKEPAAGWPVISGDYIV..GDPESPVAVTTLAS.....H...I...EAE.L.....S....---...G......AAIAGPCKTENLGVEKVVANIISNPNIRFLILAGAEVQ...GHITGQSFKALHENGA...D...P...DKKkIIGATGAIPFVENVPLDGVERFQQQL.EIIDLIDTEDVGAIQAKINECVEKDPGAFEEEAMVISVEGDDGEE-d......................
#=GC seq_cons                       .........K+tsApGWPllpG-Yhl..GcscSsVAVlTLuS.....H...h...ppt.s.....h.....pA...G......AAIsGsC+TENLGlEKllANlISNPNIRFlllCGsEVc...GHloGQulhALacNGl...s...c...cu+.IlGApGAIPFlENlsp-AlcRFQpQl.EllDhl-sEDhstIpupIcEhhuKDPGAatt-shllplttttt...tt.....................
//
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