GenomeNet

Database: Pfam
Entry: MtrA
LinkDB: MtrA
Original site: MtrA 
#=GF ID   MtrA
#=GF AC   PF04208.12
#=GF DE   Tetrahydromethanopterin S-methyltransferase, subunit A 
#=GF AU   TIGRFAMs, Finn RD
#=GF SE   TIGRFAMs (release 2.0);
#=GF GA   25.00 25.00;
#=GF TC   26.10 30.60;
#=GF NC   24.80 22.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9559648
#=GF RT   Cloning, sequencing and expression of the genes encoding the
#=GF RT   sodium translocating N5-methyltetrahydromethanopterin : coenzyme
#=GF RT   M methyltransferase of the methylotrophic archaeon
#=GF RT   Methanosarcina mazei Go1. 
#=GF RA   Lienard T, Gottschalk G; 
#=GF RL   FEBS Lett 1998;425:204-208.
#=GF DR   INTERPRO; IPR030688;
#=GF DR   TC; 3.C.1;
#=GF CC   The N5-methyltetrahydromethanopterin: coenzyme M (EC:2.1.1.86)
#=GF CC   of Methanosarcina mazei Go1 is a membrane-associated, 
#=GF CC   corrinoid-containing protein that uses a transmethylation
#=GF CC   reaction to drive an energy-conserving sodium ion pump [1].
#=GF SQ   104
#=GS B8GF36_METPE/3-173       AC B8GF36.1
#=GS A0A0G0ZEZ9_9BACT/1-158   AC A0A0G0ZEZ9.1
#=GS MTRA_METMS/4-176         AC D5E7Y7.1
#=GS A0A0G1LVK7_9BACT/1-170   AC A0A0G1LVK7.1
#=GS C1F4T6_ACIC5/100-275     AC C1F4T6.1
#=GS MTRA_METST/4-176         AC Q2NI29.1
#=GS A2STR2_METLZ/4-175       AC A2STR2.1
#=GS A0A0G1WY66_9BACT/3-159   AC A0A0G1WY66.1
#=GS MTRA1_METTH/4-176        AC O27227.3
#=GS F3KLT7_9ARCH/16-156      AC F3KLT7.1
#=GS D1YVZ3_METPS/4-174       AC D1YVZ3.1
#=GS A9A2W6_NITMS/13-155      AC A9A2W6.1
#=GS MTXA_METBF/1-167         AC O32854.1
#=GS L0HHV5_METFS/4-176       AC L0HHV5.1
#=GS MTRA_METMA/4-175         AC O59640.2
#=GS J9Z8W3_LEPFM/11-182      AC J9Z8W3.1
#=GS J1L1D4_9EURY/4-175       AC J1L1D4.1
#=GS B8GE98_METPE/4-176       AC B8GE98.1
#=GS L0L1I6_METHD/4-175       AC L0L1I6.1
#=GS D7E9H2_METEZ/4-170       AC D7E9H2.1
#=GS A0A0D5C0A8_9ARCH/14-157  AC A0A0D5C0A8.1
#=GS I0INS9_LEPFC/103-274     AC I0INS9.1
#=GS E1RDW7_METP4/4-175       AC E1RDW7.1
#=GS Q12VU8_METBU/4-176       AC Q12VU8.1
#=GS B8GEA0_METPE/4-175       AC B8GEA0.1
#=GS D5VQU3_METIM/4-177       AC D5VQU3.1
#=GS MTXA_METAC/1-167         AC Q8TPU9.1
#=GS A3CT39_METMJ/4-175       AC A3CT39.1
#=GS A0A0E3X0N1_METMT/4-176   AC A0A0E3X0N1.1
#=GS D7DUI1_METV3/4-177       AC D7DUI1.1
#=GS Q8PUT0_METMA/1-164       AC Q8PUT0.1
#=GS F6D2C8_METPW/4-176       AC F6D2C8.1
#=GS MTRA_METEZ/4-176         AC D7EBK7.1
#=GS Q2FRN1_METHJ/4-175       AC Q2FRN1.1
#=GS Q46FE9_METBF/1-162       AC Q46FE9.1
#=GS A0RXI7_CENSY/1-140       AC A0RXI7.1
#=GS A0A0E3S0V9_9EURY/1-163   AC A0A0E3S0V9.1
#=GS U6E9X4_9EURY/3-175       AC U6E9X4.1
#=GS K1ZZ81_9BACT/4-152       AC K1ZZ81.1
#=GS Q46BT7_METBF/1-166       AC Q46BT7.1
#=GS A0A0G1S0I0_9BACT/17-175  AC A0A0G1S0I0.1
#=GS Q12TW9_METBU/4-135       AC Q12TW9.1
#=GS D1YWC8_METPS/5-159       AC D1YWC8.1
#=GS A0B8Y2_METTP/4-176       AC A0B8Y2.1
#=GS L0KYT2_METHD/8-174       AC L0KYT2.1
#=GS MTXA_METMA/1-142         AC Q8Q082.1
#=GS MTRA_METHJ/4-175         AC Q2FRN2.1
#=GS A2STR4_METLZ/4-175       AC A2STR4.1
#=GS MTRA_METV3/4-179         AC D7DUI0.1
#=GS D5E6K1_METMS/61-196      AC D5E6K1.1
#=GS MTRA_METBF/4-175         AC Q9Y8K4.1
#=GS D5E6K1_METMS/5-53        AC D5E6K1.1
#=GS A0A0G1KMA0_9BACT/9-115   AC A0A0G1KMA0.1
#=GS D5E9T3_METMS/2-157       AC D5E9T3.1
#=GS K4MJD1_9EURY/10-177      AC K4MJD1.1
#=GS A6UWH8_META3/4-177       AC A6UWH8.1
#=GS A0A0G1CXL4_9BACT/2-172   AC A0A0G1CXL4.1
#=GS A0A0G1M347_9BACT/19-169  AC A0A0G1M347.1
#=GS MTRA_METJA/4-179         AC Q58261.2
#=GS A0A0E3WZ61_METMT/10-175  AC A0A0E3WZ61.1
#=GS A0A0E3L195_9EURY/1-166   AC A0A0E3L195.1
#=GS A7I5S6_METB6/4-176       AC A7I5S6.1
#=GS R9SLV8_9EURY/4-176       AC R9SLV8.1
#=GS A0A0E3NXE8_9EURY/1-164   AC A0A0E3NXE8.1
#=GS F7XQ94_METZD/4-175       AC F7XQ94.1
#=GS MTRA_METMP/4-178         AC Q6LWZ0.1
#=GS Q0W334_METAR/4-176       AC Q0W334.1
#=GS J1ANL9_9EURY/4-175       AC J1ANL9.1
#=GS A0A0G0AHW7_9BACT/34-197  AC A0A0G0AHW7.1
#=GS Q0W333_METAR/4-176       AC Q0W333.1
#=GS A0A060HGZ4_9ARCH/21-158  AC A0A060HGZ4.1
#=GS A0A0E3S083_9EURY/4-175   AC A0A0E3S083.1
#=GS F4BZJ2_METCG/4-176       AC F4BZJ2.1
#=GS A3CT41_METMJ/4-176       AC A3CT41.1
#=GS Q6LWY9_METMP/4-179       AC Q6LWY9.1
#=GS E3GZ46_METFV/4-175       AC E3GZ46.1
#=GS K4MGJ1_9EURY/4-175       AC K4MGJ1.1
#=GS MTRA_META3/4-177         AC A6UWH7.1
#=GS F0T8R8_METLA/4-176       AC F0T8R8.1
#=GS MTRA_METKA/4-181         AC O32867.3
#=GS A0A0G1HFZ6_9BACT/9-115   AC A0A0G1HFZ6.1
#=GS E3GWY7_METFV/4-167       AC E3GWY7.1
#=GS A7I5S4_METB6/4-175       AC A7I5S4.1
#=GS K0IN48_NITGG/13-157      AC K0IN48.1
#=GS A0A0G1G8W2_9BACT/18-189  AC A0A0G1G8W2.1
#=GS F7XKL5_METZD/1-167       AC F7XKL5.1
#=GS MTRA2_METRM/4-176        AC D3E0P6.1
#=GS E1RDW9_METP4/4-175       AC E1RDW9.1
#=GS H1YXH4_9EURY/4-175       AC H1YXH4.1
#=GS Q2W818_MAGSA/105-263     AC Q2W818.1
#=GS L0HFU1_METFS/4-175       AC L0HFU1.1
#=GS A0A0E3P281_9EURY/4-175   AC A0A0E3P281.1
#=GS A0A0G1QK27_9BACT/1-148   AC A0A0G1QK27.1
#=GS MTRA_METAC/4-175         AC Q8TU03.1
#=GS U6EEN6_9EURY/4-177       AC U6EEN6.1
#=GS F4C0Q4_METCG/15-179      AC F4C0Q4.1
#=GS G7WNE2_METH6/27-187      AC G7WNE2.1
#=GS Q47DR4_DECAR/95-263      AC Q47DR4.1
#=GS H1YXH2_9EURY/4-175       AC H1YXH2.1
#=GS MTRA2_METTH/7-180        AC O27134.1
#=GS MTRA1_METRM/4-176        AC D3E045.1
#=GS G7WPT7_METH6/4-176       AC G7WPT7.1
#=GS A0A0G1LRR4_9BACT/27-182  AC A0A0G1LRR4.1
#=GS A5ULY7_METS3/4-174       AC A5ULY7.1
B8GF36_METPE/3-173                  .........................kv--RPHPEYPPE.E.GR.YLR..GNDFSPVAVAIVLN.....T...D...E..D..KiPpeiehLvrvgVET...G......AALSGTVQTPNIGFEKLIWNIVGNPNIRFLVLGGPE..SE...GH.........ATGAALKELF....KNGI...D...E...QSR...IVG.SDAP.FPFLY.NIPRPVVNRFLDQV.TLVD....C-QFQDAATIREA...VRACFQEQPAVFR----------------gvmvg........................................................
A0A0G0ZEZ9_9BACT/1-158              ..........................m----AKDWPLYfK.ER.LIM..GDLSSNVGVATLWM.....P...K...E..S..VvS.....E....LDE...G.....sFSVCGQLYTKR-GINPLLRNLLANTLIRYVIVCGVD..RQ...G-.........-SGEALLKFF....KNGV...S...E...ES-...---.----.-----.--------------.----....-------------...-----------------------------ggagelkgwkilgddealldkeitkealdlirinvevfdlrmkplgevngliaslekkvpy
MTRA_METMS/4-176                    ...........................KREPAAGWPIL.K.GE.YDV..GDPENCVAVITLGS.....H...L...D..G..G.P.....M....LEA...G......ASITGPCKTENLGLEKVVSHIIANPNIRYLVVTGSE..VK...GH.........ITGEAFIMLH....KNGV...-...S...DNR...IVN.ASGA.IPYVE.NLTEEAVQRYQEQI.ECID....LIGTEDMGTISSK...IKELAAKDPDAFDADPLVIEVGGEAEEEEe............................................................
A0A0G1LVK7_9BACT/1-170              ..........................m------DWPVY.EtSQ.IIV..GNLESPVAITTLWT.....N...K...E..P..I.A.....N....-QI...Gdk..rlYCAVGTLYNRKVGIDLLVRNLLARPTIRNLIICGHD..RA...--.........RSGEALIKFFrhgfKRGV...D...G...NGNpkwIIDlSDGD.YGVIDiEVEEEMLHLLRKNV.TFLD....FRGTEDGSALCSV...LEDLHSS----------------------tkavsyaeakifp................................................
C1F4T6_ACIC5/100-275                ........................dee----RAGWPPL.P.GD.FKV..IRYGAPVAVCALNS.....T...E...L..M..K.T.....L....TEArpdG......LAIVGTMHTENLGIERVIRNTLANPNLRFLVICGTD..TQqtvGH.........LPGQSLHSLF....QNGL...D...E...KGR...IVG.AKGK.RPVLK.NVTREEVQAFLAQV.EPVS....MISEENPATVTEQ...ITACARRDPGIYPWPAGTVSV--------erirar.......................................................
MTRA_METST/4-176                    ...........................KKEVIQNWPLE.T.GD.YAV..GNVESPVAVVSLGS.....N...M...N..D..E.L.....V....-AA...G......AAISGPLHTENLGIEKVVANIISNSNIRYVLICGSE..VQ...GH.........ITGKTVEALY....ENGI...D...E...EKK..sIIG.SPGA.IPFVE.NLPVEAVERFQKQV.SIVS....MINNEDVSEISSK...IDECISNDPGAYDEDAMIVEFNETPEEE-f............................................................
A2STR2_METLZ/4-175                  ...........................KKSPANGWPII.Q.GD.YHT..GDANSPVAVITMGS.....H...L...D..E..A.G.....I....CAA...G......AALAGSCKTENLGIEKVVANVISNPNIRFVLLCGTE..VK...GH.........LSGQSIEAMH....KNGV...-...E...GGK...IVG.STGA.IPFLE.NLTAEHIKRFQEQI.ELVN....IMETEDMGQISAK...INELKGRDPGAFAADPIVIQLTDDAGG--ae...........................................................
A0A0G1WY66_9BACT/3-159              ...........................KVQPIEGWPKL.Y.HDiLKV..NDPTNHVGICTLWT.....E...R...EvvE..K.I.....L....RDL...P......YNLIGNLYSA-QGINAIIRNVFANPNIRTIVIWGSE..MS...--.........LSGHSLLSFM....KNGI...D...E...NRK...IIK.GRGE.IEV--.EIPDEAVALFRKEI.EVID....MRGR-KMPELIAK...VKELS------------------------vvkkepflakp..................................................
MTRA1_METTH/4-176                   ...........................KKSPAEGWPVV.N.GD.YIV..GDPESPVAATTLAS.....H...I...E..D..V.P.....V....-EA...G......AAIAGPCKTENLGIEKMIANLISNPNIRFLILCGSE..VQ...GH.........ITGQSIEALH....QNGV...D...P...DKR..nIIG.ATGA.IPYIE.NIPDEGIERFQKQL.EIVN....LIDVEDADAIKAK...VKECIEKDPGAFEEEAMVIKVEEGGEEEE.............................................................
F3KLT7_9ARCH/16-156                 ....................lpipeea-----------.-.--.-YL..GNADSSIAVCTLSS.....I...N...L..L..K.Q.....I....SNS...Dll..nhVAIAGRLFSENKGIDSLIRYVNQNKKIKTILVCGKE..VW...GH.........KAGHSLFELH....KNGI...D...N...HGR...IIN.STSP.DPFLT.-VTKSEIIYFQNEI.TLVN....LINETNFETIKKS...I----------------------------i............................................................
D1YVZ3_METPS/4-174                  ...........................KKEPAKGWPVV.K.GE.YDT..GDAKSPVAVATCGS.....H...F...N..L..F.P.....I....-KA...G......AAISGPFKTENLGIEKIVANVISNPNIRFLVICGSE..VK...GH.........ISGDALICLY....KYGL...-...K...DGR...IVN.AKGA.IPFIE.NLDANAVKRFQEQV.QIFE....MVDVEDEAKITQV...IKDCLAKDPGAFAGEPMLITIKEKEEE--ve...........................................................
A9A2W6_NITMS/13-155                 ......................kvvlp----------I.K.QE.FYL..GNPNSQIAICTLASislldD...L...K..D..S.E.....L....-LS...K......VAIIGRLFSENKGIDSMIQYVYENKNITKIILCGKE..VW...GH.........KSGHSLLQLH....KNGI...D...K...NSR...IIN.SVSP.DPYLT.-VSKDMIEYFQKNI.SIVD....LIDETNLEVISKK...-----------------------------l............................................................
MTXA_METBF/1-167                    ..........................m-KKIAEAWPIV.K.GD.YTV..GNPESRIAVVTLAS.....Q...I...N..S..L.P.....E....---...-......AALWGSSKTENLGVEKIIINTISNSNIRYILICGKE..SR...GH.........LAGHSLLAIH....ANGI...D...E...KGR...IVG.SEGA.IPFIE.NISREAVKRFQQQV.VLLD....RIGLTNLEEIMKI...VREYKDQ-GEVYPEEPLVA-I--------sqkkrqst.....................................................
L0HHV5_METFS/4-176                  ...........................KKSPASGWPLI.K.GD.FHS..GDANSPVAVITMGS.....H...L...D..E..Q.G.....I....CDA...G......AALCGSCKTENLGLEKVIANVIANPNIRFALLVGTE..VK...GH.........LSAQTLVALH....KNGV...-...K...DGR...VVG.AEGA.IPFIE.NLNDTHIKRFQEQV.EIVN....IMETEDVGAVKAK...INELKAKDPGAFAADPMVVEVKEAAGG--aee..........................................................
MTRA_METMA/4-175                    ...........................KREPAPGWPIL.K.GE.YEV..GDVKNSVLVITCGS.....H...L...P..G..K.P.....I....LDA...G......AACTGSCKTENLGIEKVVAHIISNPNIRYLLVTGSE..VK...GH.........ITGQSMMSLH....ANGV...-...K...ENR...IAG.ALGA.IPYVE.NLNAAAVARFQEQV.QVVN....LLDTEDMGAITSK...VRELASKDPGAFDADPLVVEISEEGEEEE.............................................................
J9Z8W3_LEPFM/11-182                 .........................pk---AQEGWPPL.P.GD.YRV..LRYQAPVAVCTLSD....iR...L...F..E..T.L.....S....KSA...Gt....gLSIIGTLHTENLGIERIITNVLGNPHIRFLIVCGAD..SRqsvGH.........LPGQSLVSLM....SAGL...D...E...KGK...ING.ALGK.RPILK.NIGRDAVEHFRNVI.TLLD....MRGVENQDEILAR...IRECTTRNPGRSD----------------pfpslptiev...................................................
J1L1D4_9EURY/4-175                  ...........................KTSPASGWPIA.K.GD.FHS..GDAKSCVAVVTMGS.....H...L...D..E..Q.G.....I....CDA...G......AALCGSCKTENLGLEKVIANIISNPNIRFVLTCGTE..VK...GH.........LSGQTFQALH....ANGI...-...E...GGK...VVG.SKGA.IPFIE.NLDDAAIKRFQAQV.ELVD....IMETEDLGAIKAK...IAELAGKDPGAFGEAPMVVEVKEAEGG--ae...........................................................
B8GE98_METPE/4-176                  ...........................KKSPASGWPIV.Q.GD.FHS..GDANSPVAVITMGS.....H...L...D..E..Q.G.....I....CDA...G......AAICGSCKTENLGLEKVVANVISNPNIRFVLLCGTE..VK...GH.........LSGQSLRQLH....SSGV...-...D...KGK...IVG.SEGA.IPFIE.NLDDAAIKRFQEQI.EIVN....IMESEDLGTIKAK...INELKGKDPGAFAGDAMVVEVKEAGGA--aee..........................................................
L0L1I6_METHD/4-175                  ...........................KREPAPQWPVL.K.GE.YEV..GDVKNCVAVITLGS.....H...L...T..G..G.P.....Q....LDA...G......ACITGPCKTENLGIEKVVVHIISNPNIRFLIVTGSE..VK...GH.........VTGDAILKMH....QNGV...-...K...DNR...IVG.AVGA.IPYIE.NLTAEAIERFQQQV.ECVN....FIGTEDTNAIVAK...IKEYAAKDPGAYDAEPMLLKIGEGGEEE-k............................................................
D7E9H2_METEZ/4-170                  ..........................l-KRIADDWPVV.K.GD.YTV..GNPESRIVVVTLAS.....S...I...E..S..N.P.....E....---...-......ACLWGTCKTENLGAEKLITNIVSNSNIRFVLLCGGE..SR...GH.........LSGHTILKLH....KNGV...D...G...KGR...IIG.SEGA.IPFVE.NIPRIAIQRFRNQV.EVID....CIGETDSEVL-GN...IVDTYKDKRDAYNEEPVLVTSKSRK----kkt..........................................................
A0A0D5C0A8_9ARCH/14-157             .....................vvlpip-----------.-.EE.YFK..GNPKSSVAICTLSS.....M...D...L..L..K.K.....F....SNS...Dil..kdISIVGRLLSENKGIDSIVEYVNNYQKINIIVVCGKE..VW...GH.........KAGHSLFELH....KNGV...D...K...NYR...IIN.SSSP.DPYLT.-VSKLKIKHFQNNV.HLVN....LINETNYEKILSK...IK---------------------------f............................................................
I0INS9_LEPFC/103-274                .........................pk---AQEGWPPL.P.GD.YRV..LRYQAPVAVCTLSD.....V...RlfeT..L..S.K.....S....VET...G......LSIIGTLHTENLGIERIITNVLGNPHIRFLIVCGAD..SRqsvGH.........LPGQSLVSLM....SAGL...D...E...KGK...ING.ALGK.RPILK.NIGRDAVEHFRNVI.TLLD....MQGVENQDEILAR...IRECTTRNPGRSD----------------pfpslptiev...................................................
E1RDW7_METP4/4-175                  ...........................KKSPASGWPKI.Q.GD.YHS..GDANSCVVVVTMGS.....H...L...D..E..Q.G.....V....CDA...G......AALCGSCKTENLGLEKIVANVVANPNIRFLITCGTE..VK...GH.........LSGQCLKALH....TGGV...-...E...GGK...IVG.AKGA.IPFIE.NLDDAAIKRFQEQV.EVID....IMETEDLGAIKAK...VQDCISKDPGAFAGDAMVIEVKESEGG--se...........................................................
Q12VU8_METBU/4-176                  ...........................KREPAVDWPTL.K.GE.YDV..GDVKNCVAVITCGS.....H...I...P..S..G.P.....Q....LEA...G......AAITGPCKTENLGLEKVVAQIIGNPNIRFVIITGSE..VK...GH.........ITGEAFIMVH....KNGV...-...S...DNR...IVG.ATGA.IPYVE.NLTDAAVERLQQQV.EMIN....MIGTEDMGQIVAK...IKECVAKDPGALDVDPMVVEVGEAGGE--gee..........................................................
B8GEA0_METPE/4-175                  ...........................KKSPASGWPIV.Q.GD.FHS..GDANSPVAVITMGS.....H...L...D..E..Q.G.....I....CDA...G......AAICGSCKTENLGLEKVVANVISNPNIRFVLLCGTE..VK...GH.........LSGQSLRQLH....SSGV...-...D...KGK...IVG.SEGA.IPFIE.NLDDAAIKRFQEQI.EIVN....IMESEDLGTIKAK...INELKGKDPGAFAADAMVVEVKEAGGS--te...........................................................
D5VQU3_METIM/4-177                  ...........................KKEPAPGWPIV.S.GE.YVV..GNPESCVGVVTLGS.....H...G...L..E..Q.A.....C....IEA...G......AAIAGPCHTENLGIEKVVANYISNPNIRFMILCGSE..VQ...GH.........ITGQCFKALW....ENGI...D...D...SGQ...IIG.AKGA.IPFLE.NVDKDAVERFRRQIvEVID....LIDCEDIGKITQA...IKECLSKDPGAIDEDPYIIQLEGGGGEE-e............................................................
MTXA_METAC/1-167                    ..........................m-KTIAENWPPV.R.GD.YVT..GKPDSRIAVVTLAS.....H...L...E..A..F.P.....N....---...-......AAIWGSSKTENLGVEKIIVNVISNSNIRYVLVCGTE..SR...GH.........LAGHSLLAIH....ANGI...D...E...KGR...IVG.SQGA.IPFIE.NISREAVDRFQRQV.TLLD....RIGLNDPEEIRKI...VEDYRDKG-EVYPEEPVVVCA--------pkkrqas......................................................
A3CT39_METMJ/4-175                  ...........................KKSPASGWPIV.Q.GD.FHT..GDAQSCVGVVTMGS.....H...L...D..E..Q.G.....I....CDA...G......AAIAGSCKTENLGLEKIIANVISNPNIRFILCCGTE..VK...GH.........LSGQSFIALH....EGGV...-...S...GGK...IVG.AQGA.IPFIE.NLSDDAISRFQEQI.EIVN....IMESEDMGAIKAK...IDELKARDPGAFGAEPMIVEVKEAGGA--ae...........................................................
A0A0E3X0N1_METMT/4-176              ...........................KREPADGWPTL.K.GE.FEL..GDVKNCVAVITLGS.....H...L...P..G..A.P.....Q....LEA...G......AAITGPCKTENLGLEKVVAQIISNPNIRFLLVTGSE..VK...GH.........ITGEAFMMFH....KNGV...-...S...DNR...IVG.ASGA.IPYVE.NLTDAAVERFQQQI.EPVE....MIGTEDMGQITAK...IKELAAKDPGAFDADPMIVEVGEGGGEEEe............................................................
D7DUI1_METV3/4-177                  ...........................KKAPATGWPVA.N.GE.YVV..GNPESCVAVVTLGS.....H...G...L..D..E.A.....A....IEA...G......AAISGPCHTENLGIEKVIVNYISNPNIRFMVVTGSE..VQ...GH.........ITGQCFKALY....ENGI...G...D...DGG...IIG.AKGA.IPFME.NVGQEPVARFQNQIvELID....MIDSEDKGKIQQT...VKDCISKDPGASEEDAMVIDLEGKAGE--ag...........................................................
Q8PUT0_METMA/1-164                  ..........................m------GWPVI.S.GD.YIV..GDPKSPVAVVTLAS.....D...Y...Q..S..L.N.....L....--K...N......YAICGTCFTENFGIEKVIVNVLSNPRISCLVVCGQE..S-...DH.........FAGQSLLALA....ENGV...S...AfggSKR...IIG.SEGV.IPYLD.DIPATAISRFLREI.EVID....LVGTTDPAVIQQA...IDSCSGKERGEA-----------------pelsmpeinehsw................................................
F6D2C8_METPW/4-176                  ...........................KKAASEGWPPV.T.GD.YEV..GDVESPVGVVTLGS.....H...M...A..D..M.P.....I....-QA...G......AAISGPLHTENLGMEKVIANIISNPNIRFLLVTGSE..VQ...GH.........ITGATMRALM....DNGV...D...P...EKR..nIID.APGA.IPYIE.NIPDEGIDRFRNQL.ELVE....MIDVEDPAAISSK...IKECIEKDPGAFEEEAMVIEVEEEGEEEE.............................................................
MTRA_METEZ/4-176                    ...........................KKEPAEGWPIL.K.GE.YEV..GDPNNCVAVITCGS.....H...L...E..G..Q.P.....M....LDA...G......ASIVGPCKTENLGLEKVVSHIISNPNIRYLIVTGAE..VK...GH.........ITGEAMMMLH....KNGV...-...K...DNR...IVG.ATGA.IPYVE.NLTEESVERLQQQLeECVD....LLGTEDLNTITSK...IKELAEKDPGAFDAEPMIIQLEEEEEEEE.............................................................
Q2FRN1_METHJ/4-175                  ...........................KGEAASGWPIV.Q.GD.FHT..GDSKSPVAVVTMGS.....H...L...D..E..G.A.....I....CSA...G......AAIAGSCKTENLGLEKVIANVISNPNIRFVITCGTE..VK...GH.........LSGQSLIALH....QNGV...-...D...GGK...IVG.SKGA.IPFIE.NLTGDHIKRFQEQV.EIVD....IMESEDIGAISAK...INELKARDPGVFPGGPMVVEIKEEGG---ggg..........................................................
Q46FE9_METBF/1-162                  ..........................m------EWPIT.S.GN.YVV..GDTNSSVAVVTLAS.....D...Y...K..E..W.G.....L....--K...N......YAICGTCFTANFGIEKIITNVLANPNINYLVVCGKE..S-...AH.........WAGQSLVSLA....ENGV...S...TmagSRK...IIG.SKSP.LSYLN.EIPMTAISRFIKEI.KIID....LIGNKDPDAIQKA...IDSCTGQK---------------------rseayivsmpeidgs..............................................
A0RXI7_CENSY/1-140                  ..........................m-----------.R.GT.VHL..GNPESTVAVCTLSS.....M...D...L..L..D.R.....I....--A...GselmeeIALAGRLLSENEGIDALIRSA-NSGNIRTVVLCGRE..VR...GH.........LAGHSLLELH....KNGI...G...P...GGR...IAG.SASP.HPVLE.SG-QAEVDLFRGRV.DIID....AIGETGLDDIGR-...-----------------------------lvrsa........................................................
A0A0E3S0V9_9EURY/1-163              ..........................m------EWPAT.S.GD.YIV..GDANSSVAVVTLAS.....D...Y...T..A..W.G.....L....--K...N......YAICGTCFTENFGIEKVIVNVLANPNINCLVVCGQE..S-...AH.........LAGQSLLSLA....ENGV...S...TmagSRK...IAG.SNSP.LPYLN.EIPMTAISRFLREI.KIID....LVGNKDPAAVQKE...IDSCTG----SKRSEAH------------iismpeidens..................................................
U6E9X4_9EURY/3-175                  ..........................g-KKSVQEWPPV.V.GD.YTI..GDVESAVAVVTLGS.....H...M...E..D..I.P.....V....-NA...G......ASISGPLHTENLGIEKVIANVVSNPNLRFLVVCGAE..VQ...GH.........ITGQSIKALH....ENGA...D...P...EKK..rING.ATGA.IPYVE.NLNEEAIQRFQDQV.EVID....MVNVEDPHQIQAQ...IKECLAQDSGAFEEESLVIQLPKKGA---hpt..........................................................
K1ZZ81_9BACT/4-152                  ....................kyysdkl-----------.-.--.-YI..GNPKSPVGLITLWS.....V...K...E..KicK.E.....I....PKQ...S......FRVAGQLYSK-RGINFLIRNIFANPEVRYIVVCGRD..ET...--.........KTGKILLDFA....RKGI...D...K...NFK...ICG.SDFS.ID--K.NIPRKDIDLLRKKV.EFVD....LIGKDDPKVIAKA...LAGCS------------------------klsgpftkpkl..................................................
Q46BT7_METBF/1-166                  ..........................m------AWPIT.S.GD.YIV..GDPKSPVAVVTLAS.....D...Y...R..N..L.N.....L....--K...N......YAICGTCFTENFGIEKIIVNVLSNPRISCLIVCGKE..S-...EH.........FAGQSLLSLA....ENGV...S...TfggSKK...IIG.SEGV.IPYLN.EIPATAISRFLREI.EVID....LVGITDPSVIQQA...IDSCSRKER--------------------seapelfmpeidenswkk...........................................
A0A0G1S0I0_9BACT/17-175             ........................svk---PIVNWPKL.Y.HDiLKV..RDPVNHVGICTLWT.....E...R...EivE..K.I.....L....DKL...P......YNVIGNLYSA-QGINAMIRNVMANPNIRTIVLWGSE..MS...--.........LSGHSLLMLM....KYGV...D...E...KRK...IIK.GRGE.IE--S.EIPDQVIEEFRHKI.EIVD....LRGQ-TKDQLVRK...MDELAKVHK--------------------epfstkpre....................................................
Q12TW9_METBU/4-135                  ........................yek-----------.-.--.---..--------------.....-...-...-..-..-.-.....-....---...-......AAMWGSCKTENLGAEKIIINTISNSNIRYVLLCGNE..SK...GH.........LAGQTLIALH....KNGI...D...N...DGR...IIG.SDGA.IPFVE.NIGKDAIERFQKQV.TIID....HIGLTDLDEIYNI...VDEYSSKGS-PYSEGPFVVEVVTK-----rktv.........................................................
D1YWC8_METPS/5-159                  ........................gdk----------I.E.KT.YKY..GDASSPVAVATLAS.....D...Y...E..K..F.D.....L....--K...G......YAILGSVFTENFGVQMAIANMLKDQNIGYLILCGQE..S-...AH.........LSGHAFVTLH....ENGVvqiG...T...SRR...IIG.CKSP.LPFID.EIPMGAIDEYQENI.KLID....MIGIEDTKLIQAK...IDECTEE----------------------skkrsyrrkpf..................................................
A0B8Y2_METTP/4-176                  ...........................KKKPAEPWPVI.T.GE.YEV..GNPESPVAVVTCGS.....H...L...N..N..A.E.....L....VAA...G......AALAGPCKTENIGIEKMVANVISNPNIRYLIITGME..VK...GH.........ITGQAIEAFT....ASGI...D...K...EGR...IVG.AKGA.IPFIQ.NLTPEAIERWRQQI.TTIN....MIDTEDMGAITAK...IKELVAKDPGALDVEPMIVEIKEGAGEE-g............................................................
L0KYT2_METHD/8-174                  .......................sidm-----NGWPLT.D.GD.YVI..GDPDSPVAVVTLAS.....D...Y...K..K..L.G.....L....--H...N......YAICGTCFTENFGIQKVIVNILSNPKISCLIVCGKE..S-...SH.........FAGQSILALV....ENGV...S...TlggYKK...IIG.SNGV.IPYLD.EIPLAAINRFIREI.EVID....LIGTTDQEIIQEA...IDSYRGKE---------------------rseapkylmseidens.............................................
MTXA_METMA/1-142                    ..........................m-----------.-.--.---..---------VTLAS.....H...L...D..A..C.P.....D....---...-......AAIWGSSKTENLGVEKIIVNVISNSNIRYVLVCGTE..SR...GH.........LAGHSLLAIH....ANGI...D...E...QGR...ITG.SQGA.IPFIE.NISGTAVERFQQQV.TVLN....RIGLNDPEEIRRI...VEDYRDK-GEAYPEEPMLVCAP-------kkrqts.......................................................
MTRA_METHJ/4-175                    ...........................KKSPASGWPIV.Q.GD.FHT..GDPNSPVAVVTMGS.....H...L...D..E..G.A.....I....CSA...G......AAIAGSCKTENLGLEKVIANVISNPNIRFVITCGTE..VK...GH.........LSGQSLIALH....QNGV...-...D...GGK...IVG.SKGA.IPFIE.NLSADNIKRFQEQV.ELVD....IMESEDLGAISAK...IKELTARDPGAFDAEAMIVEIKEEGGG--aa...........................................................
A2STR4_METLZ/4-175                  ...........................KKSPAGGWPII.Q.GD.YHT..GDANSPVAVITMGS.....H...L...D..E..T.A.....I....CVA...G......AALAGSCKTENLGIEKIVANVISNPNIRFVLLCGTE..VK...GH.........LSGQSIEAMH....KNGV...-...E...GGK...IVG.STGA.IPFLE.NLGDSDIKRFQEQV.ELIN....IMETEDLNVIAAK...INELKARDPGAFGADPVVIQLSDDDS---sgg..........................................................
MTRA_METV3/4-179                    ...........................KKAPATGWPVA.N.GE.YVV..GNPESCVAVVTLGS.....H...G...L..D..E.A.....A....IEA...G......AAISGPCHTENLGIEKVIVNYISNPNIRFMVVTGSE..VQ...GH.........ITGQCFKALY....ENGI...G...D...DGG...IIG.AKGA.IPFME.NVGQEPVARFQNQIvELID....MIDSEDKGKIQQT...VKDCISKDPGAFEEDAMVIDLEGKAG---gagee........................................................
D5E6K1_METMS/61-196                 ..................gykkpclqn-----------.-.--.---..--------------.....-...-...-..-..-.-.....-....---...-......YAICGTCFTENFGIQKVIANILSNPKINCLIVCGKE..SK...-H.........FAGQSIIALV....ENGV...StmaD...YKK...IIG.SKGV.IPYLD.EIPMTAINHFLKEI.EVID....LIDTTDPETIQKV...IDSCKLKERS-------------------eakkypipqiden................................................
MTRA_METBF/4-175                    ...........................KKEPAPGWPIL.K.GE.YEV..GDVKNCVLVITCGS.....H...L...P..G..Q.P.....I....LDA...G......AAVTGSCKTENLGIEKVVAHIISNPNIRYLLVTGSE..VK...GH.........ITGQSVMSLH....ANGV...-...K...DNR...ISG.ALGA.IPYVE.NLNEDAIARFQEQV.DVVN....LLDTEDMGAITSK...VKELASKDPGAFDAEPMIVEISEEGEEEE.............................................................
D5E6K1_METMS/5-53                   ........................kst---DPNNWPME.E.GD.YVI..GDPDSPVAVVTLTS.....D...Y...R..N..M.D.....C....I--...-......------------------------------------..--...--.........----------....----...-...-...---...---.----.-----.--------------.----....-------------...-----------------------------hdpcedgtpq...................................................
A0A0G1KMA0_9BACT/9-115              .........................ik--AKQPDWPIY.F.RDrLLL..GDLQSNVGVATCWT.....P...K...E..V..V.A.....A....-EL...Gv...knFAVCGQLYTKR-GINPLVRNILANPAIRHLVICGVD..RQ...G-.........-SGEALVRLF....AHGV...E...A...---...---.----.-----.--------------.----....-------------...-----------------------------vkgtggrle....................................................
D5E9T3_METMS/2-157                  .........................dt---VSEKWPVT.K.GD.FSA..GNTKSCIAVVTLAS.....S...M...P..L..F.E.....K....---...-......AAIWGSCKTENLGAEKVVMNVVSNCNIRYVLLCGGE..SR...GH.........LAGQTLKALY....ENGI...D...E...DGR...ILG.SEGA.IPFIE.NLEIETIQRFRQQV.ELID....RIGLTDLDEICSI...VDNYHD-----------------------sekpfeafpvs..................................................
K4MJD1_9EURY/10-177                 ........................skd----ISGWPVT.D.GD.YVI..GDPDSPVAVVTLAS.....D...Y...E..K..L.G.....L....--Q...N......YAICGTCFTENFGIQKVIVNVLSNPRINCLIVCGKE..SK...-H.........FAGQSIMALV....ENGV...StmgD...YKK...IIG.SKGV.IPYLD.EIPMTAINRFVREI.EIVD....LIDITDLETIQRA...IDSCKGKERSEAST---------------ypmpeidensw..................................................
A6UWH8_META3/4-177                  ...........................KKAPASGWPIV.S.GE.YVV..GNPESCVAVVTLGS.....H...G...L..D..E.A.....A....IEA...G......AAISGPCHTENLGIEKVVANYISNPNIRFMLVTGSE..VQ...GH.........ITGQCFKALY....ENGI...G...D...DGG...IIG.AKGA.IPFLE.NAGQDAISRFQNQLvEIVD....LIDVEDTGKISSV...IKDCISKDPGAFEEDPMILDLEGGGGE--ag...........................................................
A0A0G1CXL4_9BACT/2-172              ........................tkf-----SDWPVR.Y.KElLTL..GNFNSNIGVVCHWT.....-...I...K..D..S.Iv..ggL....DKK...T......FAAVGQLYSCDLGISSIIRNVLAHPYLDTLVLCGNEgiIE...ET.........KSSKALLNLI....NNGV...D...E...NHF...IVG.SG-Q.ARIEK.EIPIENIALFRSRI.KVVN....LIGESNPKKIQMS...INEKFRDNPQKYE----------------tivfpepqkten.................................................
A0A0G1M347_9BACT/19-169             ......................yapkl-----------.-.--.-VV..GNGRKDVAICTLWT.....K...E...DvlN..R.V.....L....SNQ...D......FGLRGPLFSQ-RGAEYIIRNVLANPVIRSILIVGAD..AN...NS.........PA--GLLALK....ENGV...G...D...RNEikgLVD.ETGKpRVYIDpGLPVEAVDRFREEV.TVED....MRDERNWDKVSKR...VAEMPQR----------------------pafdtm.......................................................
MTRA_METJA/4-179                    ...........................KREPAPGWPIV.S.GE.YVV..GNPESCVGVVTLGS.....H...G...L..E..Q.A.....C....IDA...G......AAIAGPCHTENLGIEKVVANYISNPNIRFMILCGSE..VQ...GH.........ITGQCFKALW....ENGI...G...D...DGG...IIG.AKGA.IPFLE.NVNKEAVERFRRQIvEVVD....LIDCEDIGKITQA...IKECLSKDPGAIDEDPFIIELEGGKG---ggeee........................................................
A0A0E3WZ61_METMT/10-175             .........................et---VACGWPVV.K.GD.CSA..GNSDSCIAVITLAS.....S...L...E..P..Y.D.....E....---...-......AAMWGTCKTENLGAEKIIINTVSNSNIRYLLICGSE..SR...GH.........LAGKTLVALH....KNGI...D...E...DGR...IIG.SDGA.IPFIE.NVSRDVIERFQKQV.SLIE....RIGLVDIDEIRRI...VDEYKGKE-GPYCEAAFVVESA-------rkksrp.......................................................
A0A0E3L195_9EURY/1-166              ..........................m--KVAENWPVV.K.GD.YRV..GNPESRIAVVTLAS.....H...L...E..A..Y.P.....E....---...-......AALWGSSKTENLGVEKIIVNTISNSNIRYILVCGTE..SR...GH.........LAGQSLLAIH....AGGI...D...E...QGR...IIR.SEGA.IPFIE.NVPGEAVERFQQQV.IMLD....RIGLNDTEEIRKI...VDEYRNKN-EAYPEEPLVVCS--------pkkkqcs......................................................
A7I5S6_METB6/4-176                  ...........................KKSPASGWPLV.K.GD.FHS..GDANSPVAVITMGS.....H...L...D..E..Q.G.....I....CDA...G......AAMCGSCKTENLGLEKVIANYIANPNIRFVLLCGTE..VK...GH.........LSAQSLIALH....KGGV...-...K...DGR...IVG.AEGA.IPFIE.NLNDAAIKRFQEQV.SIVN....IMETEDLNAIKAK...INELKAKDPGAFAADPLVVEVKEAAA---ggge.........................................................
R9SLV8_9EURY/4-176                  ...........................KKSPADGWPLI.S.GE.YEV..GDPESPVAATTLAS.....E...L...A..G..D.I.....V....-GA...G......AAIAGTCHTENLGVEKVVANTISNPNIRFLIVCGAE..VQ...GH.........ITGQCFEALH....ANGC...D...P...EKK..kVNG.AIGA.IPFVD.NLPLEAVERFQNQV.ELIS....MIDNEDVGAITAK...VKECIEKDPGAIEEEAMVIDVSEGGEAE-e............................................................
A0A0E3NXE8_9EURY/1-164              ..........................m------EWPVT.P.GD.YVV..GDPNSPVAVVTLAS.....D...Y...R..S..L.N.....L....--K...N......YAICGTCFTENFGIEKVIVNVLSNHRISCLLVCGKE..S-...DH.........FAGQSLLALA....ENGV...S...AfggSRK...IVG.SEGV.IPYLN.EIPATSISRFLREI.EVID....LVETTDPAVIQQA...IDSCSGEERGE------------------apelsmpeidehsw...............................................
F7XQ94_METZD/4-175                  ...........................KREPAPEWPIL.K.GE.YDI..GDVKNCVAVITLGS.....H...L...P..A..E.P.....Q....LEA...G......AAITGPCKTENLGLEKVLAHIISNPNIRYLLITGSE..VK...GH.........ITGDAFLKIH....QNGV...-...K...ENR...IVG.AVGA.IPYVE.NLTPEAIERFQQQI.ECVD....LIGTENMSEITSK...IKELASRDPDAFDADPMVVKVGEDGAEEE.............................................................
MTRA_METMP/4-178                    ...........................KKAPAAGWPVA.N.GE.YVV..GNPESCVAVVTLGS.....H...G...L..D..Q.A.....A....IDA...G......AAISGPCHTENLGIEKVVANYISNPNIRFMVITGSE..VQ...GH.........ITGQCIKALY....ENGI...G...D...DGG...IIG.AKGA.IPFME.NVGTEPVGRLQSQIvECID....LIDVEDTGKISDA...IKNCISKDPGAFEEEPMVIELEGGA----aaage........................................................
Q0W334_METAR/4-176                  ...........................KKEPAKGWPVI.K.GE.FDV..GDPKSCVAVATAGS.....H...F...G..Q..W.P.....I....-KA...G......AAISGPFHTENLGIEKIVANVISNPNIRFIIITGAE..VK...GH.........ISGDALECLH....KNGL...-...K...GGR...IVG.AKGA.IPFIE.NLDDKAVKRFQEQV.QTVY....MIDVEDEQKITAA...IKDCIAKDPGAFAGEPMLLEIKETKIGE-eee..........................................................
J1ANL9_9EURY/4-175                  ...........................KKSPASGWPIA.K.GD.FHS..GDANSCVAVVTMGS.....H...L...D..E..Q.G.....I....CDA...G......AALCGSCKTENLGLEKVIANIISNPNIRFVLTCGTE..VK...GH.........LSGQTFQALH....ANGV...-...E...GGK...VVG.SKGA.IPFIE.NLDDAAIKRFQAQV.EVVD....IMETEDLGAIKAK...IAELTGKDPGAFGEAPMVVEVKEAEGG--aa...........................................................
A0A0G0AHW7_9BACT/34-197             rvteanvglaflwtvrdsivpelekgn-----------.-.--.---..--------------.....-...-...-..-..-.-.....-....---...-......LAIASNFYTP-AGLEPMVRNILGNPYIRYVILLGEE..SS...SRkmdgnnnelTSANAIRAFF....EKGV...N...E...HRK...IDG.FKNA.IYFDN.NIPLEMIELVRVSV.ELIDlnreMLDASFEEKITAAnriMKSLERKDP--------------------faepavfgyek..................................................
Q0W333_METAR/4-176                  ...........................KKEPAKGWPVI.K.GE.FDV..GDPKSCVAVATAGS.....H...F...G..Q..W.P.....I....-KA...G......AAISGPFHTENLGIEKIVANVISNPNIRFIIITGAE..VK...GH.........ISGDALECLH....KNGL...-...K...GGR...IVG.AKGA.IPFIE.NLDDKAVKRFQEQV.QTVY....MIDVEDEQKITAA...IKDCIAKDPGAFAGEPMLLEIKETKIGE-eee..........................................................
A0A060HGZ4_9ARCH/21-158             ..................vrhesfggr-----------.-.--.---..---GREVAVCTLGSidlleR...I...S..K..S.E.....I....IMD...R......VAIAGRLLSENKGIDAIIDYVSAHPDLKRIVVCGRE..VK...GH.........MAGQALLALY....KNGI...D...G...QGR...IIG.AAGP.YPILL.-SPREKVEAFRRQV.AIAD....MTGITDLEKIM--...-----------------------------pll..........................................................
A0A0E3S083_9EURY/4-175              ...........................KREPAPGWPIL.K.GE.YEI..GDVKSCVAVITCAS.....H...L...A..G..K.P.....I....LDA...G......AAITGSCKTENLGIEKVVAGIIANPNIRFLVVTGSE..VK...GH.........VTGQSMLAVH....ANGV...-...K...DHR...IVG.SIGA.IPYVE.NLNEDVIARFQQQV.QTVN....LLDTEDMGAITAK...VRELVSKDPGAFDAEPMVVVISDEGEEEE.............................................................
F4BZJ2_METCG/4-176                  ...........................KKKPSDPWPTI.T.GE.YEV..GNPESPVAVCTCGS.....H...L...H..N..A.D.....L....IKA...G......AALAGPCKTENIGIEKMVANVISNPNIRFVLVTGME..VK...GH.........ITGQAVEAFT....QSGI...D...K...EGR...IIG.AKGA.IPFIQ.NLTPEAIERWKNQV.EAVM....MLNTEDIGAIAGK...VKELASKDPGALDVEPMAIEIKEGGEEEE.............................................................
A3CT41_METMJ/4-176                  ...........................KKSPASGWPIV.Q.GD.FHT..GDAQSCVGVVTMGS.....H...L...D..E..Q.G.....I....CDA...G......AAIAGSCKTENLGLEKIIANVISNPNIRFILCCGTE..VK...GH.........LSGQSFIALH....EGGV...-...S...GGK...IVG.AQGA.IPFIE.NLSDDAISRFQEQI.EIVN....IMESEDMGAIKAK...IDELKARDPGAFGAEPMIVEVKEAGGA--aee..........................................................
Q6LWY9_METMP/4-179                  ...........................KKAPAAGWPVA.N.GE.YVV..GNPESCVAVVTLGS.....H...G...L..D..Q.A.....A....IDA...G......AAISGPCHTENLGIEKVVANYISNPNIRFMVITGSE..VQ...GH.........ITGQCIKALY....ENGI...G...D...DGG...IIG.AKGA.IPFME.NVGTEPVGRLQSQIvECID....LIDVEDTGKISDA...IKNCISKDPGAFEEEPMVIELEGGA----aaagee.......................................................
E3GZ46_METFV/4-175                  ...........................KKEPAEGWPVV.S.GD.YIV..GDPESPVAAVTLAS.....H...I...E..D..I.P.....I....-DA...G......AAIAGPCKTENLGIEKVIANIISNPNIRFLVLCGSE..VQ...GH.........ITGQSIKALH....KNGV...D...D...KKK...IIG.AKGA.IPYIE.NLPEEALERFQKQV.EIVD....LIDVEDADQIKEK...VKECIEKDPGAFEEEAMVVKVEEEEEEG-e............................................................
K4MGJ1_9EURY/4-175                  ...........................KREAAPDWPIL.K.GE.YDV..GNIKNCVAVITCGS.....H...L...A..S..G.A.....Q....LEA...G......AAITGPCKTENLGIEKVVAHIISNPNIRYLIVTGAE..VK...GH.........ITGQAMLALH....RGGV...-...K...DNR...IVG.ATGA.IPYIE.NLTEAIIKRFQEQV.ECID....FIGTEDMNAIVAK...IKEYAAKDPGAFDADPMVVEVGGGSEEE-g............................................................
MTRA_META3/4-177                    ...........................KKAPASGWPIV.S.GE.YVV..GNPESCVAVVTLGS.....H...G...L..D..E.A.....A....IEA...G......AAISGPCHTENLGIEKVVANYISNPNIRFMLVTGSE..VQ...GH.........ITGQCFKALY....ENGI...G...D...DGG...IIG.AKGA.IPFLE.NAGQDAISRFQNQLvEIVD....LIDVEDTGKISSA...IKDCISKDPGAFEEDPMILDLEGGGGE--ag...........................................................
F0T8R8_METLA/4-176                  ...........................KKSPAEGWPVI.N.GD.YVT..GDPESPVAVATLAS.....H...N...E..Q..I.P.....V....-DA...G......AAIAGPCKTENLGIEKMISNLISNPNLRFLILCGAE..VQ...GH.........ITGESIKALH....ENGV...D...P...EKR..sIVG.APGA.IPYIE.NVPDAGLDRFRSQF.EIVD....LIDVEDAAAIQAK...VKECIEKDPGAIEEEAMVIEIEEEGEEEE.............................................................
MTRA_METKA/4-181                    ...........................KAEPAEGWPVV.E.GD.YVV..GDPEAPVHVVTLGS.....H...I...E..E..D.I.....L....KAA...Ge...dkVAIAGPCKTENIGIEKVIANVIANPNIRFGVLCGAE..VT...GH.........LTGQCFKAMY....ENGV...D...P...DSG..eIIG.AEGA.IPYLE.NIPEEAVERYRDQIvELVD....LIDVEDVDEIVKA...IEECVEKDPGAYEEGPMTISLEEEEEEE-l............................................................
A0A0G1HFZ6_9BACT/9-115              .........................ik--AKQPDWPIY.F.RDrLLL..GDLQSNVGVATCWT.....P...K...E..V..V.A.....A....-EL...Gv...knFAVCGQLYTKR-GINPLVRNILANPAIRHLVICGVD..RQ...G-.........-SGEALVRLF....AHGV...E...A...---...---.----.-----.--------------.----....-------------...-----------------------------vkgtggrle....................................................
E3GWY7_METFV/4-167                  ...........................KKEPAEGWPVV.S.GD.YIV..GDPESPVAAVTLAS.....H...I...E..D..I.P.....I....-DA...G......AAIAGPCKTENLGIEKVIANIISNPNIRFLVLCGSE..VQ...GH.........IVGQSMKALH....KNGV...D...D...KRK...IIG.AKGA.IPYIE.NLPEEALERFQKQV.EIVD....LIDVEDADQIKEK...VKECIEKDPGAFEEEEVILR---------l............................................................
A7I5S4_METB6/4-175                  ...........................KKSPATGWPLV.K.GD.FHS..GDANSPVAVITMGS.....H...L...D..E..Q.G.....I....CDA...G......AAMCGSCKTENLGLEKVIANYIANPNIRFVLLCGTE..VK...GH.........LSAQSLVALH....KGGV...-...K...DGR...IVG.AEGA.IPFIE.NLNDAAIKRFQEQV.SIVN....IMETEDLNAIKAK...INELKAKDPGAFAADPLVVEVKEAAA---gga..........................................................
K0IN48_NITGG/13-157                 ...................kvceavlp----------I.K.HE.YHL..GMGKE-LAICTLSSmdlleK...L...S..K..S.D.....P....VMN...K......IAIAGRLLSENRGIDAMIKFALDHPELRRIIVCGKE..VK...GH.........RAGQALLALA....RNGI...D...R...NGR...IVG.ALGP.YPILE.S-PAGDVDAFRQQV.EILD....MIGTTDIEKL---...-----------------------------lva..........................................................
A0A0G1G8W2_9BACT/18-189             ....................kkstidl-----SNWPIY.Y.KDiLKI..KNPKHHVAVCCLWT.....E...R...QviE..T.L.....L....KDV...E......YNTIGNLYS-AQGINAMIRNIFTNPHIRVIVVWGAE..MS...--.........LSGHSLLMLN....QKGI...E...K...DSR..kIKG.GRGE.IE--K.EIPDEVLEEFRKYV.EVVD....MRGRTAV-ELVEE...VRRLSAQHKDAFANTQ-------------rtfpvaeiavtq.................................................
F7XKL5_METZD/1-167                  .........................me--HVANDWPPA.K.GD.YVI..GSIDSRIAVVTLAS.....S...I...E..P..T.E.....K....---...-......AAIWGTCKTENLGVEKVVINIISNSNIRYLLLCGGE..SR...GH.........LSGKSLIALH....NNGI...D...E...NGR...IIG.SDGA.IPFIE.NIPENAIIRFQEQV.DLID....YTGLTDKKEIYEL...VD-VYSNKNEAYAEEPFVILTGK------rkksc........................................................
MTRA2_METRM/4-176                   ...........................KKPTAENWPVV.S.GD.YIV..GDPESPVAVTTLAS.....H...N...E..D..I.P.....A....-AA...G......AAIAGPCKTENLGIEKVVANIISNPNIRFLILCGAE..VQ...GH.........ITGQSFKALY....ENGC...D...P...EKK..kITG.ATGA.IPFVE.NIPMEGVERFQQQL.ELVD....MIDNEDGGAITAK...VKECIEKDPGAFEEDSLVIKIDEER----yskk.........................................................
E1RDW9_METP4/4-175                  ...........................KKSPASGWPKI.Q.GD.YHT..GDANSCVVVVTMGS.....H...L...D..E..Q.G.....V....CDA...G......AAMCGSCKTENLGLEKIVANVISNPNIRFLITCGTE..VK...GH.........LSGQCLKALH....AGGV...-...E...GGK...IVG.AKGA.IPFIE.NLNDAAIKRFQEQV.ELID....IMETEDLGAIKAK...VQECISKDPGAFEGDAMVIEVKEEEGG--ag...........................................................
H1YXH4_9EURY/4-175                  ...........................KRAPASGWPKI.Q.GD.YHA..GNAESPVAVVTVGS.....H...L...D..E..Q.G.....I....CDA...G......AAICGSCKTENLGLEKIVANVVANPNIRFMVTCGTE..VK...GH.........LSGQCLHALH....ANGL...-...E...GGK...IVG.AKGA.IPFIE.NLTDESIQRFRDQI.EMVD....IMESEDMGAIKAK...IDELTARDPGAFDGEPIVLEVKEDDGG--aa...........................................................
Q2W818_MAGSA/105-263                ........................fei----REGWPPV.P.GD.YFVlcHGADCTVAVSTLGD.....V...A...L..A..A.R.....I....ADL...Kp...paLCMVGKTETENIGIDKVVRNVAANPDITTLILVGQD..PP...GH.........QPGRTLLALA....ENGV...D...E...AMR...VIG.SPGK.RPILR.NVTPDEVATFRQRV.QIID....LIGEIDPGRIIAA...IEQH-------------------------ntpapqk......................................................
L0HFU1_METFS/4-175                  ...........................KKSPASGWPLI.K.GD.FHS..GDANSSVAVITMGS.....H...L...D..E..Q.G.....I....CDA...G......AALCGSCKTENLGLEKVIANVIANPNIRFALLVGTE..VK...GH.........LSAQTLVALH....KNGV...-...K...DGR...VVG.AEGA.IPFIE.NLNDTHIKRFQEQV.EIVN....IMETEDVGAVKAK...INELKAKDPGAFAADPMVVEVKEAAGG--qe...........................................................
A0A0E3P281_9EURY/4-175              ...........................KRDPAPGWPIL.K.GE.YEV..GDVQGCVAVITCAS.....H...L...P..G..K.P.....V....LDA...G......AAITGSCKTENLGIEKVVAHVISNPNIRYLVVTGAE..VK...GH.........ITGQAALSLH....ENGV...-...K...ENR...IVG.AIGA.IPYVE.NLNPEAVERFQAQV.ETVE....LLNTEDMGVITAK...VKELVSKDPGAFDAEPLVVEISEEGEGEE.............................................................
A0A0G1QK27_9BACT/1-148              ..........................m------DWPIL.Y.KHvLHV..KDPANPVGVAIMWT.....E...R...Q..V..V.A.....D....LLK...Ge....nYCAIGNLY-SSAGISAMIRNIYANPHIRKIVLWGAD..LS...R-.........-SGQALLSLM....QNGV...D...E...SFF...IVG.DEKK.GQIEK.EIGRKNIELFRKSV.KVVN....LR-----------...-----------------------------grpvsefvrvvsdlrdvpkk.........................................
MTRA_METAC/4-175                    ...........................KKEPASGWPIL.K.GE.YEV..GDVKGCVAVITCAS.....H...L...P..G..K.P.....V....LDA...G......AAITGSCKTENLGIEKVVAHVISNPNIRYLVVTGAE..VK...GH.........VTGQAMLSIH....ANGV...-...K...EHR...IVG.AVGA.IPYVE.NLNDDAVARFQQQI.ETVN....LLDTEDMGAITAK...VRELVAKDPGAFDAEPMVVEISEEGEEEE.............................................................
U6EEN6_9EURY/4-177                  ...........................KKSPAEGWPVI.N.GD.YVV..GDPESPVAATTLAS.....H...I...E..Q..I.A.....V....-DA...G......AAISGPCKTENLGIEKMIANLISNPNIRFLILTGSE..VQ...GH.........ITGQSIESLH....KNGV...D...P...EKR..kIVG.ATGA.IPFIE.NIPDEGIERFQQQM.EIVS....IIDVEDAATIQSK...VKECIDKDPGAFEEEAMVIKVEEGEGDE-ee...........................................................
F4C0Q4_METCG/15-179                 .......................qgyl-----DPWPPV.R.GE.YRL..GDPRAGVAVVTLAS.....V...F...N..P..R.-.....-....---...G......TAISGPCKTENLGLEKIVANVISNSNIRFLIVCGVE..SK...GH.........LPGNTLLALH....KNGI...D...E...KGR...IIG.SKGA.IPFIQ.NLSVQAVERFQRQV.ELID....RIGLEDMKEIEKL...VSQY-------------------------nhlampfpeepyqvikrkaarqe......................................
G7WNE2_METH6/27-187                 ........................rad---EAGRWPPL.R.GE.YSL..GDPGSRIAVVTLAS.....S...L...R..-..-.-.....-....-AP...G......AAIWGPCKTENLGVEKVVGNLISNSEIRFLLVCGEE..SK...GH.........LPGDSIVALH....RNGI...D...K...DGR...IVG.SRGA.IPFIE.NLSPEAIDRFQRQV.EVID....RIGLVDEDEIERI...VREHR------------------------slsepfpeppmevvkrr............................................
Q47DR4_DECAR/95-263                 .......................epqe----REGWPPL.P.GD.YHV..VRYQAPVAVCTLNS.....DdlvV...R..L..T.A.....T....QAP...G......LAVVGSLHTENLGIEHLIRNLLPNPHIRFLIVCGED..TRkaiGH.........LPGQSLVALM....RNGL...E...D...GGR...IRG.AEGK.RPVIK.NVPPEHVEAFRRQV.QVVD....CIGMTDLEGIAAE...IARAAADDPGP------------------apeiftdl.....................................................
H1YXH2_9EURY/4-175                  ...........................KKSPASGWPKI.Q.GD.YHA..GDAESPVVVVTVGS.....H...L...D..E..Q.A.....V....CDA...G......AAMCGSCKTENLGLEKIVANVIANPNIRFIITCGTE..VK...GH.........LSGQCLIALH....ANGL...-...E...GGK...IVG.AKGA.IPFIE.NLTDEGVQRFREQV.EIVD....IMESEDMGTIKAK...IEELKGRDPGAFDGDPIVIEVKEDGA---ggd..........................................................
MTRA2_METTH/7-180                   ...........................KKPVPEDWPHI.V.GD.YVV..GDEESPVAVVTLGS.....H...M...E..D..E.P.....V....-KA...G......AAISGPLHTENLGIEKVVGNVIANPNLRFLVVCGAE..VM...GH.........ITGQTMKALH....SNGV...D...L...ETG..rIIG.ATGA.IPYIE.NMPEEAIERFRRQV.ELVD....MVDVEDPDSIAAR...IQECVVHDSGAMEEEPLILKVPEIGKG--dse..........................................................
MTRA1_METRM/4-176                   ...........................KKPAADNWPVV.S.GD.YIV..GDPESPVAVTTLAS.....H...N...E..D..I.P.....A....-AA...G......AAIAGPCKTENLGIEKVVANIISNPNIRFLILCGAE..VQ...GH.........ITGQSIQALH....ENGC...D...P...EKK..kITG.ATGA.IPFVE.NIPMEGVERFQQQV.ELVD....LIDNEDGGAITAK...VKECIEKDPGAFEEDAMVIEVKEGDDDE-d............................................................
G7WPT7_METH6/4-176                  ...........................KKPTSDPWPWL.T.GE.YVV..GNPESPVAVVTCGS.....H...L...N..N..A.P.....F....IDA...G......SALAGPCKTENIGIEKMVANIISNPNIRFLIITGME..VK...GH.........ITGQAIEAFA....ANGI...D...Q...EGR...IVG.ATGA.IPFIQ.NLTPEAIERFKQQI.TTIN....IIDTEDTGTIVSK...IKECVSKDPGALDVEPMAVEISEGEAEEE.............................................................
A0A0G1LRR4_9BACT/27-182             ........................idl-----SNWPLL.Y.KDiLKV..KNPRHHVAVCCLWT.....E...R...QviE..T.L.....L....KDV...E......YNTVGNLYSG-QGINAMIRNIFANPHIRVIILWGAE..MS...--.........LSGHSLLMLK....QKGV...D...E...TSR..kIVA.ARGE.IE--K.EIPDDMLEEFRKVV.DVVD....MRGRQA-TDFVAK...VKELSA-----------------------tpiepfsakt...................................................
A5ULY7_METS3/4-174                  ...........................KKEPAAGWPVI.S.GD.YIV..GDPESPVAVTTLAS.....H...I...E..A..E.L.....S....---...G......AAIAGPCKTENLGVEKVVANIISNPNIRFLILAGAE..VQ...GH.........ITGQSFKALH....ENGA...D...P...DKK..kIIG.ATGA.IPFVE.NVPLDGVERFQQQL.EIID....LIDTEDVGAIQAK...INECVEKDPGAFEEEAMVISVEGDDGEE-d............................................................
#=GC seq_cons                       .............................tsupsWPll.p.G-.Yhl..GcscSsVAVlTLuS.....+...h...p..p..t.s.....h.....pu...G......AAIsGsC+TENLGIEKllsNlISNPNIRalllCGsE..Vp...GH.........loGQulhALa....cNGl...s...c...ps+...IlG.upGA.IPalE.NlspculcRFppQl.EllD....hlssEDhstIpsp...lc-hhs+-PGuhtttshllph........t............................................................
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