GenomeNet

Database: Pfam
Entry: NESP55
LinkDB: NESP55
Original site: NESP55 
#=GF ID   NESP55
#=GF AC   PF06390.11
#=GF DE   Neuroendocrine-specific golgi protein P55 (NESP55)
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_16185 (release 9.0)
#=GF GA   22.60 22.60;
#=GF TC   22.60 22.70;
#=GF NC   22.50 22.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12438142
#=GF RT   Neuroendocrine secretory protein 55: a novel marker for the
#=GF RT   constitutive secretory pathway. 
#=GF RA   Fischer-Colbrie R, Eder S, Lovisetti-Scamihorn P, Becker A,
#=GF RA   Laslop A; 
#=GF RL   Ann N Y Acad Sci 2002;971:317-322.
#=GF DR   INTERPRO; IPR009434;
#=GF CC   This family consists of several mammalian
#=GF CC   neuroendocrine-specific golgi protein P55 (NESP55) sequences.
#=GF CC   NESP55 is a novel member of the chromogranin family and is a
#=GF CC   soluble, acidic, heat-stable secretory protein that is expressed
#=GF CC   exclusively in endocrine and nervous tissues, although less
#=GF CC   widely than chromogranins [1].
#=GF SQ   50
#=GS G3V916_RAT/1-256         AC G3V916.1
#=GS A5GFT7_PIG/1-250         AC A5GFT7.1
#=GS W5P401_SHEEP/1-230       AC W5P401.1
#=GS M3WND3_FELCA/1-247       AC M3WND3.1
#=GS E2RBZ7_CANLF/1-247       AC E2RBZ7.1
#=GS GNAS3_HUMAN/1-245        AC O95467.1
#=GS L9L887_TUPCH/348-552     AC L9L887.1
#=GS L9L887_TUPCH/1-246       AC L9L887.1
#=GS G3TLL4_LOXAF/1-247       AC G3TLL4.1
#=GS G3GWT8_CRIGR/116-159     AC G3GWT8.1
#=GS A0A091DJR7_FUKDA/1-229   AC A0A091DJR7.1
#=GS GNAS3_BOVIN/1-241        AC O18979.1
#=GS H2BTI3_9FLAO/16-125      AC H2BTI3.1
#=GS GNAS3_MOUSE/1-257        AC Q9Z0F1.2
#=GS C4Y0X1_CLAL4/626-796     AC C4Y0X1.1
#=GS C0N3G6_9GAMM/313-447     AC C0N3G6.1
#=GS L5M895_MYODS/1-242       AC L5M895.1
#=GS H0Y7Z6_HUMAN/1-113       AC H0Y7Z6.1
#=GS A0A0D5YSZ2_9FLAO/8-125   AC A0A0D5YSZ2.1
#=GS G1S9I9_NOMLE/1-244       AC G1S9I9.1
#=GS A0A0D9SBM2_CHLSB/1-251   AC A0A0D9SBM2.1
#=GS S7Q0E8_MYOBR/1-242       AC S7Q0E8.1
#=GS G1RC94_NOMLE/853-1006    AC G1RC94.2
#=GS G3GWT8_CRIGR/149-295     AC G3GWT8.1
#=GS H0XJJ1_OTOGA/1-260       AC H0XJJ1.1
#=GS L5KZZ0_PTEAL/785-947     AC L5KZZ0.1
#=GS M0WCE4_HORVD/79-176      AC M0WCE4.1
#=GS I3CBA0_9FLAO/7-125       AC I3CBA0.1
#=GS G1TF12_RABIT/1-240       AC G1TF12.1
#=GS A0A177VZA7_BATDE/87-178  AC A0A177VZA7.1
#=GS U6GMM8_9EIME/211-340     AC U6GMM8.1
#=GS A0A0H1BBT6_9EURO/49-253  AC A0A0H1BBT6.1
#=GS K1WC94_MARBU/4-89        AC K1WC94.1
#=GS A0A177WU51_BATDE/81-177  AC A0A177WU51.1
#=GS A6PW70_MOUSE/1-59        AC A6PW70.1
#=GS G1PXY8_MYOLU/1-242       AC G1PXY8.1
#=GS F6S3D5_HORSE/1-250       AC F6S3D5.1
#=GS A6PW71_MOUSE/1-25        AC A6PW71.1
#=GS A0A177WN53_BATDE/76-173  AC A0A177WN53.1
#=GS A0A0P0DAK1_9FLAO/8-125   AC A0A0P0DAK1.1
#=GS A2A2S1_HUMAN/1-166       AC A2A2S1.1
#=GS D8TJY0_VOLCA/9-171       AC D8TJY0.1
#=GS F7DQ13_CALJA/1-253       AC F7DQ13.1
#=GS G3GWT8_CRIGR/1-113       AC G3GWT8.1
#=GS S9Y7I7_CAMFR/146-387     AC S9Y7I7.1
#=GS I3C2L9_9FLAO/10-125      AC I3C2L9.1
#=GS GNAS3_RAT/1-256          AC Q792G6.1
#=GS H2BXS8_9FLAO/30-137      AC H2BXS8.1
#=GS D5BAA9_ZUNPS/8-126       AC D5BAA9.1
#=GS D2H1X6_AILME/1-245       AC D2H1X6.1
G3V916_RAT/1-256                    ......................................................MDRRSRAHQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALASSNARAQQR..AA...........QR...RSFLNAHHRSAAA.AAAAQVLPESSESESDHEH.....E..EAEPE....LARPEC.LEYDQDDYETET.DSETEPESDIQSETE..FETEPET.EPE.TA.P.TTEPETE..PEDERG....P...R.GATF......NQ..SLT...QRLHALKLQ.S.ADASPRRAQPTTQEPESASEGEEPQREP..LDEDPRDPEESE.ELR-E...ANRQPRRCKTR.RPAR.RRDQSPESPPRKGPIPIRRH...........................................................................
A5GFT7_PIG/1-250                    ......................................................MDRRSRAQQGRRARHTYSDLCPPIGRRAATALLWLSCSIALLRALATSSARAQQR.aAA...........QR...RSFLNAHHRS---.--AAPVFPQP--PESDQEQ.....E..EADLE....LSLPEC.LEYE-EEFDYE-.-SETETESEIESETD..SETEPET.APT.TE.P.ETEPETE..PEDERGp.vlP...K.RPSF......AQ..SLT...ERLNALRLQ.S.PDASPSRAQPSTQESESPREGEEPKPEP..EDKDPRGPEESE.EPKAE...EKKQQRRCKPK.KPT-.RRDPSPESPSKRGPIPIRRH...........................................................................
W5P401_SHEEP/1-230                  ......................................................MDRRSRPQLGRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSSP-----..--...........-S...RSFLNAHHRS---.--AAQVFPEP--PESDHED.....T..DLEPS....L--PEC.PEYQEEEFDYE-.-SETESESEIESETE..F----ET.ESD.TA.P.TTEPETE..PEDERGp.vvP...K.RPTF......HQ..SLT...ERLSALRLR.S.PDASPSRAPPSTQESESPRQREEPE---..-DKDPRDPEESE.EPKEE...EKEQQRRCKPK.KPT-.RRDPSPESPSKRGPL-----afp........................................................................
M3WND3_FELCA/1-247                  ......................................................MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQRaaAQ...........QR...RSFLNAHHRS---.--GAQVFPEP--PESDHEH.....E..EADLE....LSLPEC.LEYE-EEFDYES.ESETETESEIESETD..F----ET.EPE.TA.P.ATEPETE..PEDERGp.vvP...K.HTTF......GQ..SLT...ERLHALRLR.S.PDASPSRAQPSTQEPQNPRQGEEPE--P..EDKDPRDPEESE.EPKEE...EKKQQRRCKPK.KPT-.RRDPSPESPSKRGPIPIRRH...........................................................................
E2RBZ7_CANLF/1-247                  ......................................................MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQRaaAQ...........QR...RSFLNAHHRS---.--GAQVFPEP--PESDHEH.....E..EADLE....LSLPEC.LEYE-EEFDYES.ETETETESEIESETD..F----ET.EPE.TA.P.ATEPETE..PEDERGp.vvP...K.HSSF......GQ..SLT...ERLHALRLR.S.PDASPSRAQPSTQEPQNPREGEEPEPKP..EDKDPRDPEESE.EPK--...EKKQQRRCKPK.KPT-.RRDPSPESPSKRGPIPIRRH...........................................................................
GNAS3_HUMAN/1-245                   ......................................................MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQRaaAQ...........QR...RSFLNAHHRS---.--GAQVFPESPESESDHEH.....E..EADLE....LSLPEC.LEYE-EEFDYET.ESET--ESEIESETD..F----ET.EPE.TA.P.TTEPETE..PEDDRGp.vvP...K.HSTF......GQ..SLT...QRLHALKLR.S.PDASPSRAPPSTQEPQSPREGEELK--P..EDKDPRDPEESK.EPKEE...--KQRRRCKPK.KPT-.RRDASPESPSKKGPIPIRRH...........................................................................
L9L887_TUPCH/348-552                .................................................lhvqt---------------------------------------------------ALQRaaAQ...........QR...RSFLNAHHRS---.--GAQVFPEPPESESDHEHeh.ehE..EADLE....LSLPEC.LEYQ-ESFDYE-.-TETETESEIESETD..FETDP--.EPE.TA.P.TTEPETE..PEEERGp.vaP...K.NPHS......GQ..SLA...QRLHALKLQ.S.PHTSPSRAQPGIHERRGPRQGEEPE--P..KDKDPRDPEESE.EPREE...--KQQRRCKPK.KPT-.RRDPSPESPSKRGPIPIRRH...........................................................................
L9L887_TUPCH/1-246                  ......................................................MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQRaaAQ...........QR...RSFLNAHHRS---.--GAQVFPEPPESESDHEHeh.ehE..EADLE....LSLPEC.LEYQ-ESFDYE-.-TETETESEIESETD..FETDP--.EPE.TA.P.TTEPETE..PEEERGp.vaP...K.NPHS......GQ..SLA...QRLHALKLQ.S.PHTSPSRAQPGIHERRGPRQGEEPE--P..KDKDPRDPEESE.EPREE...--KQQRRCKPK.KPT-.RRDPSPEAPH----------xxxxx......................................................................
G3TLL4_LOXAF/1-247                  ......................................................MDRRSRAYQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQR..AAa........qqQR...RSFLNAHHRS---.--AAQVVPEP--PESDQEQ.....D..EGELD....LSLIEC.LEYE-EEFDYE-.-SETETESEIEYETD..FETDFET.--E.TA.P.TTEPETE..PEDERSp.vvP...K.RPTF......GQ..SLT...ERLNALKLR.S.PDASPSRAQPSTQEPQSPTEGEVPV--P..EQKDPRDPED--.-PKEE...QKKQRRRCKPKsKKSS.RRDPSPEPPSKRGPIPIRRH...........................................................................
G3GWT8_CRIGR/116-159                ...............................................raelpra-------------------------------------------------------..--...........--...-------------.-------------------.....-..----V....LARPEC.LDYDDIESETES.ESETESETETETETE..TE-----.---.--.-.-------..------....-...-.----......--..---...---------.-.----------------------------..------------.-----...-----------.----.--------------------t..........................................................................
A0A091DJR7_FUKDA/1-229              ......................................................MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQR.aAG...........QH...RSFLNAHHRS---.--SAPVFPESSESDSDHER.....E..EGDLE....LSLPEC.LEYE-EEFDYE-.---TETESEIESETD..F------.---.--.-.ETEPETE..PEDERGp.pvP...K.GSTF......NQ..SLT...QRLYALKLQ.S.PDA-----QPTTQEPQSSSEGEELE--P..NQKDPRDPEESA.EPK--...EKQQQRRCKPK.KPS-.RRDRSPESPSKKGPIPIRR-f..........................................................................
GNAS3_BOVIN/1-241                   ......................................................MDRRSRPQLGRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSSTRAQQR.aAA...........QR...RTFLNAHHRS---.--AAQVFPEP--PESDHED.....T..DFEPS....L--PEC.PEYQEEEFDYE-.-SETESESEIESETE..F----ET.ESD.TA.P.TTEPETE..PEDEPGp.vvP...K.RPTF......HQ..SLT...ERLSALRLR.S.PDASPSRAPPSTQESESPRQGEEPE---..-DKDPRDPEESE.EPKEE...EKQQQHRCKPK.KPT-.RRDPSPESPSKRGAIPIRRH...........................................................................
H2BTI3_9FLAO/16-125                 ............................rfqefsrthfkshteamgtmldfffy-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.------------.---------------..-------.---.--.-.---NEIS..PKEKLG....P...T.GRTI......EA..SIK...KRINAVIAI.M.RDMEKTQTKPTVAMIESLFQTEAPAKKP..LILEKKFIEEKK.EVRFQ...EKQNP------.----.--------------------nne........................................................................
GNAS3_MOUSE/1-257                   ......................................................MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALASSNARAQQR..AA...........QR...RSFLNAHHRSAAA.AAAAQVLPESSESESDHEH.....E..EVEPE....LARPEC.LEYDQDDYETET.DSETEPESDIESETE..IETEPET.EPE.TA.P.TTEPETE..PEDERG....P...R.GATF......NQ..SLT...QRLHALKLQ.S.ADASPRRAQPTTQEPESASEGEEPQRGP..LDQDPRDPEEEP.EERKE...ENRQPRRCKTR.RPAR.RRDQSPESPPRKGPIPIRRH...........................................................................
C4Y0X1_CLAL4/626-796                ..........tlpsssvraerekpqthassthfssaqakqtgvnapalqaskpt-------------------------------------------------------..--...........--...------------A.RGKLQSLDEF-FGDSDDES.....E..SAADS....QLESESeEELDSGLVTSES.ESESESESESESESE..SDAESES.ESE.GGgS.EAEPESD..PEDESGasgsD...D.KPTF......AS..---...---------.-.----------------------------..------------.-----...-----------.----.--------------------htaadrqnklskhalssvdydsdgsgrst..............................................
C0N3G6_9GAMM/313-447                .............................ttvivddtpqqeskqvelaqrdela-------------------------------------------------------..--...........--...-------------.-------------------.....-..DLLAE....I--PVA.IEHSETETETET.ETETETETETETETE..TETETET.ETE.TE.T.ETETETE..TEGDLP....P...QtKQAL......SQ..PNT...ANTAVISEQkA.ADN-------------------------..------------.-----...-----------.----.--------------------qaaksaeaevqdsdwilsqkpt.....................................................
L5M895_MYODS/1-242                  ......................................................MDRRSRA-HWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNTRAQQR..AA...........AR...RSFLNAHHRS---.--AAQVIPEP--PNSDSDQ.....E..EADQD....LSRPEC.PDYE-EEFDYE-.-SETESESDIESDID..F----DT.ETE.TA.P.TTEPETE..PEDERG....PaalR.QRAF......GQ..SLT...QRLQALRVR.S.PDASPTRSQPRSQQPRSPREGEEPQPGP..RDRDLRDPEESE.KPK--...EKQQRGGCKPR.KPT-.RRDPSPESPSRRGPIPIRR-f..........................................................................
H0Y7Z6_HUMAN/1-113                  .....................................................x-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.------------.---------------..-------.---.--.-.TTEPETE..PEDDRGp.vvP...K.HSTF......GQ..SLT...QRLHALKLR.S.PDASPSRAPPSTQEPQSPREGEELK--P..EDKDPRDPEESK.EPKEE...--KQRRRCKPK.KPT-.RRDASPESPSKKGPIPIRRH...........................................................................
A0A0D5YSZ2_9FLAO/8-125              .........................................rfkketakrfqef-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.------------.-----------SRTH..FKTHTEA.MEAiLD.F.FFYNEIS..PKENLG....P...T.GRTI......EA..KLL...KRINAVIAI.M.RDVEKTQTKPTVAMLQSLFEMEEPEEKP..LILEKKFAEEKK.EVKFQ...EKRNNQ-----.----.--------------------nq.........................................................................
G1S9I9_NOMLE/1-244                  ......................................................MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQR.aAA...........QR...RSFLNAHHRS---.--GAQVFPESPESESDYEH.....E..EADLE....LSLPEC.LEYE-EEFDYQT.ESET--ESEIESETD..F----ET.EPE.TA.P.TTEPETE..PEDERGp.vvP...K.HSTF......GQ..SLT...QRLHALKLR.S.PDASPNRAPPSTQEPQSPREGEELK--P..EDKDPRDPEESK.KPKEE...--KQRRRCKPK.KPT-.RRDASPESPSKKGPIPIRRH...........................................................................
A0A0D9SBM2_CHLSB/1-251              ......................................................MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQRaaAQ...........QR...RSFLNAHHRS---.--GAQVFPESPESESDHEH.....E..EADLE....LSLPEC.LEYE-EEFDYET.ESET--ESEIESETD..F----ET.EPE.TA.P.TTEPETE..PEDERGp.vvP...K.HSTFgqsltdSQ..SLT...QRLHALKLR.S.PDASPSRAPPSTQEPQSPREGEELK--P..EDKDPRAPEESE.EPKKE...--KQRRRCKPK.KPT-.RRDASPESPSKKGPIPIRRH...........................................................................
S7Q0E8_MYOBR/1-242                  ......................................................MDRRSRA-HWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNTRAQQR..AA...........AR...RSFLNAHHRS---.--AAQVIPEP--PNSDSDQ.....E..EADQD....LSRPEC.PDYE-EEFDYE-.-SETESESDIESDID..F----DT.ETE.TA.P.TTEPETE..PEDERG....PaalR.QRAF......GQ..SLT...QRLQALRVR.S.PDASPTRSQPRSQQPRSSREGEEPQPGP..RDRDLRDPEESE.KPK--...EKQQRGGCKPR.KPT-.RRDPSPESPSRRGPIPIRR-f..........................................................................
G1RC94_NOMLE/853-1006               retysetdkndnsthkmsssflgsqknvspgftkiqqpveeeseldleleseqe-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.---AGLGLDLDL.DRELEPESELEPEIEpkAETETET.EME.PQ.P.ETEPEME..PDPKSR....P...R.AHTF......PQ..Q--...---------.-.----------------------------..------------.-----...-----------.----.--------------------hywpmchpsmastqsqtqprtwsverrrhpmdsyspegn....................................
G3GWT8_CRIGR/149-295                .....................................................t-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.--------ETET.ETETETESDIESETE..T--ETET.ESD.TA.P.ATEPETE..PEDERG....P...R.GATF......NQ..SLT...QRLHALKLQ.S.ADASPRRAQPTTQESESDSEGEEPQRGP..LDQDPRDPEESDsDERQE...EARQPRRCKTR.RLARrRRDQSPESPPRKGPIPIRRH...........................................................................
H0XJJ1_OTOGA/1-260                  ......................................................MDRRSRAHQWRRARHNYHDLCPPIGRRTATALLWLSCSIALLRALAASNARAQQR..AAaqqqqqqqqqqQR...RSFLNAHHRS---.--GAQVYPDSPESESDRET.....EevDFEPS....L--PEC.LEYE-DDFEYET.ESESESESEIESETD..F----ET.ETD.TA.P.TTEPETE..PEDERGp.vvP...K.QSTF......PQ..SLT...ERLQALKLR.S.PDASPSRAGPSTQEPQNTTEGEEPEKTPepEYQDPRNPEESE.ESK--...EKKRQRRCKPK.KSP-.RRDPSPESPKKKGPIPIRRH...........................................................................
L5KZZ0_PTEAL/785-947                ..........................etdkdaesrhkisssildapknvssgft-------------------------------------------------------..--...........--...-------------.-----MIQEPITEEESELD.....M..ELEPT....L---ES.EQEAMRGLDLDL.CSELEPESELEPESE..LEPETEL.EPE.TE.L.ELEPEPE..PEPEPK....P...K.SKSR......PR..DQTyswQQYWPLYQQ.SkPSSSLSQTQPRTQSVERRRQHM------..------------.-----...-----------.----.--------------------nsyspkgsdted...............................................................
M0WCE4_HORVD/79-176                 .......................................nlkvsleeiapppqp-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.----EPEQEQEL.ESESEPEEDLESEPE..P--ELES.ESE.SE.P.EEDLESE..PEQELE....P...E.-LTF......WE..KTW...QVLHILRCK.GlADLDPKRN--------------------..------------.-----...-----------.----.--------------------alvptrv....................................................................
I3CBA0_9FLAO/7-125                  ....................irfkketakrfqqfsrthfkshteamatmldfff-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.------------.---------------..-------.---.--.-.--YNEIS..PREKLG....P...T.GRTI......EA..NLK...KRINAVIAI.M.RDMEKTQTKPTAAMIESLFQSEEPKKKP..LILEKKFVEEKP.KVKFQ...EKQNH------.----.--------------------nne........................................................................
G1TF12_RABIT/1-240                  ......................................................MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSSARAQQR.aAA...........QR...RSFLNAHHRT---.--AAQVFPESPESESDHEH.....E..EAHVD....LSLPEC.LEFEGEEFDYES.ESETESESEIESETD..F----ET.EPE.TA.P.ATEPETEpePEDERGp.avP...K.GSAF......NQ..SLT...QRLQALKLR.S.---------PSAQQPPNPREGEEPGRAA..E--SRSDPAEPQ.EPK--...EKKQQRRCRPK.KPT-.RRDQSPESPSRKGPIPIRRH...........................................................................
A0A177VZA7_BATDE/87-178             ...............................................lpatepa-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.-----TEFDTEL.VTDSDLESDIESDTE..FVADSDL.ESD.TE.S.DTEPEPS..KTQEQK....D...K.GAEV......S-..--S...KNLHELVLK.S.DKCGPNH---------------------..------------.-----...-----------.----.--------------------grckgslccsdy...............................................................
U6GMM8_9EIME/211-340                ........................................prcieantlwrsqf-------------------------------------------------------..-A...........QRlptKTFTTAVSAAAAA.ASAAAVGPNSSSTTTTNTR.....I..QTATGtgrgFSSDGF.IETEEDQRETET.ETETETETETETETE..TETETET.ETE.GE.T.ETETETE..TETETE....T...-.----......--..---...---------.-.----------------------------..------------.-----...-----------.----.--------------------etdtlrdr...................................................................
A0A0H1BBT6_9EURO/49-253             ..................................................grlf---------GRRERHQGNG-VPPAERRAAEQVNLQLTKVANLTGAASFQRPIASS..DA...........NR...HRHSYAPQASRDY.TRCIRNLPICTDSESEHQDaapeaQ..EVDIA....IDEPDI.HPLRMHPIDNNAqHSRQTSISDVASGAE..VVEEPPG.EPE.TA.A.VAEASTT..NDK-ND....A...E.ASTT......N-..---...---------.-.----------------------------..------------.-----...-----------.----.--------------------dnntgvaeeggsnsgdtppppgqedvaadvpssphsdtwsvhp................................
K1WC94_MARBU/4-89                   .............................................lrsgstyda-------------------------------------------------------..--...........--...-------------.-------------------.....-..SQKPR....LITPPE.AEPVQAEPETEP.EAEPEAEPETEPETE..LETEPEA.EPE.TE.P.EAEPEAK..LEGEPK....A...K.----......--..---...---------.-.----------------------------..------------.-----...-----------.----.--------------------vqdglffrkip................................................................
A0A177WU51_BATDE/81-177             ..............................................nlpatepa-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.-----TEFDTEL.VTDSDLESDIESDTE..FVADSDL.ESD.AE.S.DTESEPS..KTREQK....D...K.GAEV......S-..--S...KNLHELVLK.S.DKCGPKHG--------------------..------------.-----...-----------.----.--------------------rckgslccsdrgycg............................................................
A6PW70_MOUSE/1-59                   ......................................................-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.------------.---------------..-------.---.--.-.-------..------....-...-.----......--..---...---------.-.---------------------EEPQRGP..LDQDPRDPEEEP.EERKE...ENRQPRRCKTR.RPAR.RRDQSPESPPRKGPIPIRRH...........................................................................
G1PXY8_MYOLU/1-242                  ......................................................MDRRSRA-HWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNTRAQQR..AA...........AR...RSFLNAHHRS---.--AAQVIPEP--PNSDSDQ.....E..EADQD....LSRPEC.PDYE-EEFDYE-.-SETESESDIESDID..F----DT.ETE.TA.P.TTEPETE..PEDERG....PaalR.QRAF......GQ..SLT...QRLQALRVR.S.PDASPTRSQPRSQQPRSSREGEEPRPGP..RDRDLRDPEESE.KPK--...EKQQGGGCKPR.KPT-.RRDPSPESPSRRGPIPIRR-f..........................................................................
F6S3D5_HORSE/1-250                  ......................................................MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQRaaAQ...........QR...RSFLNAHHRS---.--GAQAFPEP--PESDQEH.....E..EADLE....LSLPEC.LEYE-EEFDYE-.-SETETESEIESETD..F----ET.EPE.TA.P.ATEPETE..PEDERGp.vvP...K.RPTF......GErgSLT...QRLQALRLR.S.PDASPSRAQPSTQEPQSPREGEEPE--P..EDKDPRDPEESE.EPKEKekkEKQQQRRCKPK.KPT-.RRDPSPESPSKRGPIPIRRH...........................................................................
A6PW71_MOUSE/1-25                   ......................................................-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.------------.---------------..-------.---.--.-.-------..------....-...-.----......--..---...---------.-.----------------------------..------------.-----...----------R.RPAR.RRDQSPESPPRKGPIPIRRH...........................................................................
A0A177WN53_BATDE/76-173             .........................................hcevknlpatepa-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.-----TEFDTEL.VTDSDLESDIESDTE..FVADSDL.ESD.TE.S.DTEPEPS..KTREQK....D...K.GAEV......S-..--S...KNLHELVLK.S.DKCGPNH---------------------..------------.-----...-----------.----.--------------------grckgslccsdy...............................................................
A0A0P0DAK1_9FLAO/8-125              .........................................rfkketakrfqef-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.------------.-----------SRTH..FESHTEAlETM.LD.F.FFYNEIS..PKEKLG....P...T.GRTI......EA..SLK...KRINAVIAI.M.RDMEKTQTKPTVAMIESLFQTNEPSKKP..LILEKKTVEEKP.KVRFQ...EKQNH------.----.--------------------tne........................................................................
A2A2S1_HUMAN/1-166                  .....................................................p-------------------------------------------------------..--...........--...-------------.-----------ESESDHEH.....E..EADLE....LSLPEC.LEYE-EEFDYET.ESET--ESEIESETD..F----ET.EPE.TA.P.TTEPETE..PEDDRGp.vvP...K.HSTF......GQ..SLT...QRLHALKLR.S.PDASPSRAPPSTQEPQSPREGEELK--P..EDKDPRDPEESK.EPKEE...--KQRRRCKPK.KPT-.RRDASPESPSKKGPIPIRRH...........................................................................
D8TJY0_VOLCA/9-171                  ...............................................aygqliv-------------------------------------------------------..--...........--...-------------.AKDALVHPEEDEGK-LKDD.....S..EDETD....LEDSET.ESGTESETESET.ESESESESESESETE..SETASES.ETE.TE.T.ATEAETT..ET-ER-....-...-.----......--..---...---------.-.----------------------------..------------.-----...-----------.----.--------------------sttvtgtgdfksprpqqhlpaesmpslssppgdgvgkrsqasspkgspsrnpiaapryyqpppppppapmpkpre
F7DQ13_CALJA/1-253                  ......................................................MDRRSRAQQWRRARQNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQRaaAQ...........QR...RSFLNAHHRS---.--GAQVFPESPESESDHEH.....E..EADLE....LSLPEC.LEYE-EEFDYET.ESET--ESEIESETD..F----ET.EPE.TA.P.ATEPETE..PEDERGp.vvP...K.HSTFgqslaeSQ..SLT...QRLHALKLR.S.PDTSPSRAPPSTQEPQSPSEGEELK--P..EDKDPTDPEESE.EPK-E...EKQQRRRCKPK.KKPT.RREESPESPSKKGPIPIRRH...........................................................................
G3GWT8_CRIGR/1-113                  ......................................................MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALASSNARAQQR..AA...........QR...RSFLNAHPPSAAAaAAAAQVLPESPESESDQEL.....E..GARAE....LPRAEL.P-----------.---------------..-------.---.--.-.-------..------....-...-.----......--..---...---------.-.----------------------------..------------.-----...-----------.----.--------------------raelprae...................................................................
S9Y7I7_CAMFR/146-387                ......................................................MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSSARAQQR.aAA...........QR...RSFLNAHHRS---.--AAQVFPGP--PESDHEQ.....E..EADLE....LSLPEC.LEYE-EEFDYE-.-SETETESEIESETD..F----ET.EPE.TA.P.ATEPETE..PEDERGp.vvP...K.RPTF......AQ..SLT...ERLNALRLR.S.PDASPSRAQPSTQQSQSPGEGEEPE--P..EDKDPRDPKESE.EPK--...EKKQQRRCKPK.KPT-.RRDPSPESPSKRGPIPIRRH...........................................................................
I3C2L9_9FLAO/10-125                 ...........................................krktakrfqef-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.------------.-----------SKTH..FKTHTEA.MEN.IL.DfFFYNEIS..PKEKLG....P...T.GRTI......EA..KLL...KRINAVIAI.M.RDVEKTQTKPTVAMIQSLFETEQPNKKP..LILEKKYAEEKK.EVRFR...EKQNP------.----.--------------------snq........................................................................
GNAS3_RAT/1-256                     ......................................................MDRRSRAHQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALASSNARAQQR..AA...........QR...RSFLNAHHRSAAA.AAAAQVLPESSESESDHEH.....E..EAEPE....LARPEC.LEYDQDDYETET.DSETEPESDIQSETE..FETEPET.EPE.TA.P.TTEPETE..PEDERG....P...R.GATF......NQ..SLT...QRLHALKLQ.S.ADASPRRAQPTTQEPESASEGEEPQREP..LDEDPRDPEESE.E-RRE...ANRQPRRCKTR.RPAR.RRDQSPESPPRKGPIPIRRH...........................................................................
H2BXS8_9FLAO/30-137                 ..............................qefskthfkshteamatmldfffc-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.------------.---------------..-------.---.--.-.---NEIS..PREKLG....P...T.GRTI......EA..KLL...KRINAVIAI.M.RDMEKTQTKPTVAMMESLFQAEEPKRKP..LILEKKFTEERK.EVRFQ...EKRNT------.----.--------------------sne........................................................................
D5BAA9_ZUNPS/8-126                  ......................rfknetakrfqefskthfkshtealetmldff-------------------------------------------------------..--...........--...-------------.-------------------.....-..-----....------.------------.---------------..-------.---.--.-.-FYNEIS..PKEKLG....P...T.GRTI......EA..KLL...KRINAVIAI.M.RDVEKTQTKPTVAMIQSLFEIEEPKKKP..LIVEKKYAEEQP.KVRFR...EKQNHH-----.----.--------------------neh........................................................................
D2H1X6_AILME/1-245                  ......................................................MDRRSRAQQWRRARHSYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQRaaAQ...........QR...RSFLNAHHRS---.--AAQVFPEP--PESDHEH.....E..EGDLE....LSLPEC.LEYE-EEFDYES.ETETETESEIESETD..F----ET.EPE.TA.P.ATEPETE..PEDERGp.vvP...K.HTTF......GQ..SLT...ERLHALRLR.S.PDASPSRAQPSTQEPQNTRQGEEPE---..-DKDPRDPEESE.EPKEE...GKKQQRRCKPK.KPT-.RRDPSPESPSKRGPIPIRRH...........................................................................
#=GC seq_cons                       .....................................................................................................................................................h.....spppppp........phc.p....L..sEs..-hp.p-h-hE...oEoEsES-lESET-..h....Es.Es-.Tt.s.sTEPETE..PE-EpG....P...+.ttTh......sp..sLo...pRLpALhlp.S.sDss.sps.Psst..ps..psEE.p..P.....-.+.sEEp..cs+.......pp.t..........................................................................................................
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