GenomeNet

Database: Pfam
Entry: Noelin-1
LinkDB: Noelin-1
Original site: Noelin-1 
#=GF ID   Noelin-1
#=GF AC   PF12308.5
#=GF DE   Neurogenesis glycoprotein
#=GF AU   Assefa S, Gavin OL
#=GF SE   PFAM-B_3817 (release 23.0)
#=GF GA   25.00 25.00;
#=GF TC   25.70 25.20;
#=GF NC   24.30 23.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11784068
#=GF RT   The secreted glycoprotein Noelin-1 promotes neurogenesis in
#=GF RT   Xenopus.
#=GF RA   Moreno TA, Bronner-Fraser M;
#=GF RL   Dev Biol. 2001;240:340-360.
#=GF DR   INTERPRO; IPR022082;
#=GF CC   This domain family is found in eukaryotes, and is approximately
#=GF CC   100 amino acids in length. The family is found in association
#=GF CC   with Pfam:PF02191. There are two conserved sequence motifs: SAQ
#=GF CC   and VQN. Noelin-1 is a glycoprotein which is secreted mainly by
#=GF CC   postmitotic neurogenic tissues in the developing central and
#=GF CC   peripheral nervous systems, first appearing after neural tube
#=GF CC   closure. It is likely that it forms large multimeric
#=GF CC   complexes.It has a divergent function in neurogenesis. In animal
#=GF CC   caps neuralized by expression of noggin, co-expression of
#=GF CC   Noelin-1 causes expression of neuronal differentiation markers
#=GF CC   several stages before neurogenesis normally occurs in this
#=GF CC   tissue. Finally, only secreted forms of the protein can activate
#=GF CC   sensory marker expression, while all forms of the protein can
#=GF CC   induce early neurogenesis.
#=GF SQ   239
#=GS H2LML1_ORYLA/18-117         AC H2LML1.1
#=GS M3W9N6_FELCA/31-130         AC M3W9N6.1
#=GS G3WAD0_SARHA/1-55           AC G3WAD0.1
#=GS M3X6N8_FELCA/24-120         AC M3X6N8.1
#=GS G1NXI8_MYOLU/46-145         AC G1NXI8.1
#=GS H3A5F8_LATCH/47-146         AC H3A5F8.1
#=GS I3ND57_SPETR/14-113         AC I3ND57.1
#=GS H3CB30_TETNG/6-105          AC H3CB30.1
#=GS M3YKV7_MUSPF/26-125         AC M3YKV7.1
#=GS M3X9W7_FELCA/36-135         AC M3X9W7.1
#=GS W5K9L2_ASTMX/1-54           AC W5K9L2.1
#=GS W5KK58_ASTMX/54-153         AC W5KK58.1
#=GS F6XID5_MONDO/49-147         AC F6XID5.2
#=GS E1BUB7_CHICK/52-151         AC E1BUB7.2
#=GS H2SYC3_TAKRU/52-151         AC H2SYC3.1
#=GS F7CTG0_MONDO/46-145         AC F7CTG0.1
#=GS U3J435_ANAPL/1-82           AC U3J435.1
#=GS F1R5K6_DANRE/52-151         AC F1R5K6.1
#=GS A0A0D9S6M2_CHLSB/13-112     AC A0A0D9S6M2.1
#=GS F7C4L1_CALJA/46-145         AC F7C4L1.1
#=GS F6V4B9_MACMU/26-81          AC F6V4B9.1
#=GS X1WFJ9_DANRE/13-112         AC X1WFJ9.1
#=GS F7EDG3_MONDO/36-135         AC F7EDG3.1
#=GS I3JB54_ORENI/27-126         AC I3JB54.1
#=GS U3IQ19_ANAPL/4-103          AC U3IQ19.1
#=GS F6WV18_HORSE/36-135         AC F6WV18.1
#=GS A0A0A0MXJ7_PAPAN/25-121     AC A0A0A0MXJ7.1
#=GS G3PW76_GASAC/50-149         AC G3PW76.1
#=GS H2SYC4_TAKRU/38-137         AC H2SYC4.1
#=GS NOE3_HUMAN/46-145           AC Q96PB7.1
#=GS K7EIS8_HUMAN/1-45           AC K7EIS8.1
#=GS G3PWT1_GASAC/1-50           AC G3PWT1.1
#=GS G3X9Q7_MOUSE/26-125         AC G3X9Q7.1
#=GS H3AZZ1_LATCH/1-56           AC H3AZZ1.2
#=GS A0A091D9E7_FUKDA/46-145     AC A0A091D9E7.1
#=GS L5L3M9_PTEAL/9-107          AC L5L3M9.1
#=GS L5LQG1_MYODS/1-53           AC L5LQG1.1
#=GS A0A0D9R5L3_CHLSB/1-45       AC A0A0D9R5L3.1
#=GS Q6DBT0_DANRE/26-125         AC Q6DBT0.1
#=GS F7HZJ8_CALJA/25-121         AC F7HZJ8.1
#=GS G1RBX1_NOMLE/36-135         AC G1RBX1.1
#=GS G7PR72_MACFA/18-117         AC G7PR72.1
#=GS F6ZCY5_ORNAN/45-144         AC F6ZCY5.1
#=GS L5K4Y0_PTEAL/46-149         AC L5K4Y0.1
#=GS V8NWC3_OPHHA/46-145         AC V8NWC3.1
#=GS H0W0L9_CAVPO/34-133         AC H0W0L9.1
#=GS NOE3_RAT/46-145             AC P63057.1
#=GS G1SDG0_RABIT/26-125         AC G1SDG0.2
#=GS H2SYC7_TAKRU/13-112         AC H2SYC7.1
#=GS F1MDY6_BOVIN/26-125         AC F1MDY6.1
#=GS I3LLD2_PIG/54-152           AC I3LLD2.1
#=GS M7BG89_CHEMY/54-153         AC M7BG89.1
#=GS H2PZI2_PANTR/46-145         AC H2PZI2.1
#=GS A6QPI8_BOVIN/26-125         AC A6QPI8.1
#=GS H2SYC8_TAKRU/1-98           AC H2SYC8.1
#=GS W5KRL1_ASTMX/24-123         AC W5KRL1.1
#=GS G3IJL3_CRIGR/26-125         AC G3IJL3.1
#=GS H2MTK2_ORYLA/1-99           AC H2MTK2.1
#=GS H2LML3_ORYLA/14-113         AC H2LML3.1
#=GS H2TBZ3_TAKRU/29-128         AC H2TBZ3.1
#=GS W5KHY6_ASTMX/54-153         AC W5KHY6.1
#=GS G3P636_GASAC/52-151         AC G3P636.1
#=GS I3JZ46_ORENI/54-153         AC I3JZ46.1
#=GS A0A096N6V8_PAPAN/54-153     AC A0A096N6V8.1
#=GS H2LEZ1_ORYLA/54-153         AC H2LEZ1.1
#=GS L5LXH7_MYODS/231-330        AC L5LXH7.1
#=GS K7EKW2_HUMAN/49-147         AC K7EKW2.5
#=GS G1SMC5_RABIT/1-53           AC G1SMC5.2
#=GS A0A087Y2U8_POEFO/28-127     AC A0A087Y2U8.2
#=GS G3TDJ6_LOXAF/16-112         AC G3TDJ6.1
#=GS M4AUA2_XIPMA/3-60           AC M4AUA2.1
#=GS F7H3M1_MACMU/46-145         AC F7H3M1.1
#=GS F6V489_MACMU/36-91          AC F6V489.1
#=GS F6U4R3_MACMU/25-121         AC F6U4R3.1
#=GS F7CQB6_HORSE/8-104          AC F7CQB6.1
#=GS H2LEY7_ORYLA/26-125         AC H2LEY7.1
#=GS M7BC92_CHEMY/46-145         AC M7BC92.1
#=GS G3PTR4_GASAC/54-153         AC G3PTR4.1
#=GS H2M0G5_ORYLA/1-98           AC H2M0G5.1
#=GS H2MZE3_ORYLA/26-125         AC H2MZE3.1
#=GS A0A087Y5G5_POEFO/3-102      AC A0A087Y5G5.2
#=GS L8YCC6_TUPCH/56-155         AC L8YCC6.1
#=GS F7EDF9_MONDO/54-153         AC F7EDF9.1
#=GS A0A087X9L0_POEFO/52-151     AC A0A087X9L0.2
#=GS A0A087XG78_POEFO/23-122     AC A0A087XG78.2
#=GS A3KGE4_MOUSE/11-110         AC A3KGE4.1
#=GS G3NBD6_GASAC/27-126         AC G3NBD6.1
#=GS F1MTJ5_BOVIN/19-115         AC F1MTJ5.1
#=GS H2RMY8_TAKRU/39-139         AC H2RMY8.1
#=GS C3YEW5_BRAFL/31-129         AC C3YEW5.1
#=GS H2RVD4_TAKRU/27-126         AC H2RVD4.1
#=GS G3WPL4_SARHA/46-145         AC G3WPL4.1
#=GS M4AJT1_XIPMA/37-136         AC M4AJT1.1
#=GS F7H3M5_MACMU/46-145         AC F7H3M5.1
#=GS G5AYR0_HETGA/46-145         AC G5AYR0.1
#=GS F8W870_HUMAN/43-142         AC F8W870.1
#=GS I3JB53_ORENI/42-141         AC I3JB53.1
#=GS G1RMV4_NOMLE/46-145         AC G1RMV4.1
#=GS G1LVY1_AILME/37-134         AC G1LVY1.1
#=GS H3CS59_TETNG/19-119         AC H3CS59.1
#=GS G3THR5_LOXAF/4-103          AC G3THR5.1
#=GS H2TBZ4_TAKRU/25-124         AC H2TBZ4.1
#=GS F6UYR7_CANFA/46-145         AC F6UYR7.1
#=GS M7BS18_CHEMY/88-152         AC M7BS18.1
#=GS G1KBH1_ANOCA/26-125         AC G1KBH1.2
#=GS H3BGU2_LATCH/26-125         AC H3BGU2.1
#=GS H3BGU1_LATCH/38-137         AC H3BGU1.1
#=GS F6RAY1_CALJA/55-143         AC F6RAY1.1
#=GS G1M0Y6_AILME/25-121         AC G1M0Y6.1
#=GS H2MTK3_ORYLA/1-99           AC H2MTK3.1
#=GS H2QFA5_PANTR/25-121         AC H2QFA5.1
#=GS G5B6W4_HETGA/37-158         AC G5B6W4.1
#=GS F5GZQ2_HUMAN/1-70           AC F5GZQ2.1
#=GS A0A091DCH1_FUKDA/1219-1315  AC A0A091DCH1.1
#=GS H2MTK0_ORYLA/19-118         AC H2MTK0.1
#=GS F7HKM5_MACMU/26-125         AC F7HKM5.1
#=GS H2SYC6_TAKRU/25-124         AC H2SYC6.1
#=GS B7ZD18_DANRE/16-75          AC B7ZD18.1
#=GS G3QT74_GORGO/23-119         AC G3QT74.1
#=GS H9G952_ANOCA/49-148         AC H9G952.2
#=GS NOE2_MOUSE/19-118           AC Q8BM13.2
#=GS G1RMX8_NOMLE/24-120         AC G1RMX8.1
#=GS G3P960_GASAC/36-135         AC G3P960.1
#=GS G3WZT5_SARHA/54-153         AC G3WZT5.1
#=GS W5MK37_LEPOC/50-149         AC W5MK37.1
#=GS M3ZEN4_XIPMA/25-125         AC M3ZEN4.1
#=GS H9GCE6_ANOCA/1-70           AC H9GCE6.2
#=GS H0WUT4_OTOGA/54-153         AC H0WUT4.1
#=GS V8PIM3_OPHHA/14-113         AC V8PIM3.1
#=GS G7NV38_MACFA/46-145         AC G7NV38.1
#=GS Q8R357_MOUSE/54-153         AC Q8R357.1
#=GS F7FV23_ORNAN/26-125         AC F7FV23.1
#=GS I3IUH3_ORENI/52-151         AC I3IUH3.1
#=GS B7ZD15_DANRE/54-153         AC B7ZD15.1
#=GS H0X2N5_OTOGA/5-102          AC H0X2N5.1
#=GS M3ZHZ3_XIPMA/25-124         AC M3ZHZ3.1
#=GS H2RVD3_TAKRU/26-125         AC H2RVD3.1
#=GS F1S3G6_PIG/5-101            AC F1S3G6.2
#=GS H2LML0_ORYLA/52-151         AC H2LML0.1
#=GS F6Y788_XENTR/53-152         AC F6Y788.1
#=GS G3RJC5_GORGO/36-135         AC G3RJC5.1
#=GS I3KQC2_ORENI/25-124         AC I3KQC2.1
#=GS I3MQI5_SPETR/59-158         AC I3MQI5.1
#=GS M4AUL7_XIPMA/36-135         AC M4AUL7.1
#=GS V8NTM5_OPHHA/12-111         AC V8NTM5.1
#=GS R4GEF0_DANRE/51-147         AC R4GEF0.1
#=GS M3YKV4_MUSPF/36-135         AC M3YKV4.1
#=GS F6ZCX8_ORNAN/27-126         AC F6ZCX8.1
#=GS H2M0G6_ORYLA/52-151         AC H2M0G6.1
#=GS F1R4X5_DANRE/25-124         AC F1R4X5.1
#=GS G3STF8_LOXAF/46-145         AC G3STF8.1
#=GS G1LVW6_AILME/36-133         AC G1LVW6.1
#=GS H2UFP3_TAKRU/51-150         AC H2UFP3.1
#=GS H0WRE7_OTOGA/47-146         AC H0WRE7.1
#=GS W5NV91_SHEEP/36-135         AC W5NV91.1
#=GS Q6DGM5_DANRE/26-125         AC Q6DGM5.1
#=GS G3RLQ0_GORGO/46-145         AC G3RLQ0.1
#=GS F6V4D7_MACMU/23-78          AC F6V4D7.1
#=GS M4ATN0_XIPMA/52-151         AC M4ATN0.1
#=GS W5L727_ASTMX/1-54           AC W5L727.1
#=GS H0Z6H8_TAEGU/54-153         AC H0Z6H8.1
#=GS H2NXH6_PONAB/1-53           AC H2NXH6.2
#=GS F1N764_BOVIN/36-135         AC F1N764.2
#=GS I3IWH6_ORENI/30-129         AC I3IWH6.1
#=GS W5MMX5_LEPOC/25-124         AC W5MMX5.1
#=GS K7ELC6_HUMAN/1-43           AC K7ELC6.1
#=GS W5PVN8_SHEEP/49-145         AC W5PVN8.1
#=GS G1L428_AILME/54-153         AC G1L428.1
#=GS M3YSX6_MUSPF/1-55           AC M3YSX6.1
#=GS NOE1_RAT/54-153             AC Q62609.1
#=GS I3IZI4_ORENI/52-151         AC I3IZI4.1
#=GS NOE1_MOUSE/54-153           AC O88998.1
#=GS F7BXL7_XENTR/1-52           AC F7BXL7.1
#=GS D3YTM3_MOUSE/13-112         AC D3YTM3.1
#=GS H2UFP4_TAKRU/50-149         AC H2UFP4.1
#=GS F5H810_HUMAN/1-50           AC F5H810.1
#=GS E2RQL9_CANFA/55-154         AC E2RQL9.2
#=GS F1S570_PIG/46-145           AC F1S570.1
#=GS H2N6L8_PONAB/26-125         AC H2N6L8.1
#=GS F7FV31_ORNAN/27-126         AC F7FV31.1
#=GS W5QAR8_SHEEP/46-145         AC W5QAR8.1
#=GS NOE1_CHICK/54-153           AC Q9IAK4.1
#=GS H2VEA1_TAKRU/54-153         AC H2VEA1.1
#=GS R7PRK2_9FIRM/9-100          AC R7PRK2.1
#=GS F7C449_CALJA/26-125         AC F7C449.1
#=GS F7CJF2_CALJA/26-125         AC F7CJF2.1
#=GS NOE1_HUMAN/54-153           AC Q99784.4
#=GS L5K742_PTEAL/1-70           AC L5K742.1
#=GS B7ZD16_DANRE/54-153         AC B7ZD16.1
#=GS U3IYJ8_ANAPL/47-146         AC U3IYJ8.1
#=GS H2MTK1_ORYLA/5-104          AC H2MTK1.1
#=GS C3XRI0_BRAFL/16-114         AC C3XRI0.1
#=GS H3DMI7_TETNG/53-152         AC H3DMI7.1
#=GS U3JG49_FICAL/54-153         AC U3JG49.1
#=GS F7I1T3_CALJA/44-140         AC F7I1T3.1
#=GS F6Q7Q2_HORSE/26-125         AC F6Q7Q2.1
#=GS G1N4M6_MELGA/57-156         AC G1N4M6.1
#=GS G5B357_HETGA/1-54           AC G5B357.1
#=GS L8YCW6_TUPCH/54-153         AC L8YCW6.1
#=GS A2AWU2_DANRE/54-153         AC A2AWU2.1
#=GS U3JIH3_FICAL/25-124         AC U3JIH3.1
#=GS H0XV76_OTOGA/53-152         AC H0XV76.1
#=GS W5LWC1_LEPOC/90-189         AC W5LWC1.1
#=GS H0Z3M4_TAEGU/46-145         AC H0Z3M4.1
#=GS A2AWU1_DANRE/54-153         AC A2AWU1.1
#=GS H2SYC5_TAKRU/18-117         AC H2SYC5.1
#=GS W5KK57_ASTMX/26-125         AC W5KK57.1
#=GS H3CC10_TETNG/54-153         AC H3CC10.1
#=GS B7ZD17_DANRE/26-125         AC B7ZD17.1
#=GS H2TBZ5_TAKRU/20-119         AC H2TBZ5.1
#=GS A0A087XKG0_POEFO/1-50       AC A0A087XKG0.1
#=GS NOE3_MOUSE/46-145           AC P63056.1
#=GS F1P6C4_CANFA/8-104          AC F1P6C4.2
#=GS G1PBQ6_MYOLU/5-101          AC G1PBQ6.1
#=GS G3P962_GASAC/26-125         AC G3P962.1
#=GS A0A096MRZ8_PAPAN/46-145     AC A0A096MRZ8.1
#=GS NOE2_HUMAN/25-121           AC O95897.2
#=GS F1QM40_DANRE/3-102          AC F1QM40.2
#=GS A0A0A0MV29_PAPAN/22-118     AC A0A0A0MV29.1
#=GS A4IHX8_XENTR/54-153         AC A4IHX8.1
#=GS H2LLZ9_ORYLA/26-125         AC H2LLZ9.1
#=GS H2M0G3_ORYLA/52-151         AC H2M0G3.1
#=GS W5MK23_LEPOC/23-122         AC W5MK23.1
#=GS A0A091CQS4_FUKDA/21-120     AC A0A091CQS4.1
#=GS H2PTW9_PONAB/52-117         AC H2PTW9.1
#=GS I3M5U5_SPETR/4-103          AC I3M5U5.1
#=GS G5B8J0_HETGA/4-103          AC G5B8J0.1
#=GS I3L7A4_PIG/28-124           AC I3L7A4.1
#=GS H0W3G4_CAVPO/9-105          AC H0W3G4.1
#=GS H3DBM5_TETNG/1-101          AC H3DBM5.1
#=GS H2M0G0_ORYLA/1-97           AC H2M0G0.1
#=GS A2AWU3_DANRE/26-125         AC A2AWU3.1
#=GS U3JG48_FICAL/26-125         AC U3JG48.1
#=GS H0VK67_CAVPO/46-145         AC H0VK67.1
#=GS H2RVD5_TAKRU/38-137         AC H2RVD5.1
#=GS A0A093BFQ9_CHAPE/1-52       AC A0A093BFQ9.1
#=GS A0A087YA69_POEFO/26-125     AC A0A087YA69.2
#=GS NOE2_RAT/49-148             AC Q568Y7.1
#=GS H2VEA2_TAKRU/27-126         AC H2VEA2.1
H2LML1_ORYLA/18-117                    ...............................p-SPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNISQSMEVLDLRTYRDLEYVKNTESLMKVVDGKLKVASENPRSLNPKGFQE............................
M3W9N6_FELCA/31-130                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
G3WAD0_SARHA/1-55                      ................................--------------------------------------------ME.K.....VQNVSQSMEVLELRTFRDLQYVRNTESLMRSLDSRLRAADG-ARSLSAKSFQE............................
M3X6N8_FELCA/24-120                    ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLMG.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRAADG---SLSAKSFQE............................
G1NXI8_MYOLU/46-145                    ...............................v-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
H3A5F8_LATCH/47-146                    ...............................i-SPKEGWRVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLKQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMNGLNAKFRQIEVDQKTLMTKHFQE............................
I3ND57_SPETR/14-113                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
H3CB30_TETNG/6-105                     ...............................s-VPEENWQVYSSAQDSDGRCVCTVVAPQQTVCSRDARTQQLKHLLE.K.....VQNMSHSIEILDQRTQRDLKFVENMEFQLKTLENKFKDVEDGHESNTARQYK-s...........................
M3YKV7_MUSPF/26-125                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
M3X9W7_FELCA/36-135                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFRQVEESHRQHLARQFK-a...........................
W5K9L2_ASTMX/1-54                      ................................----------------------------------------------.Q.....VQNVSQYLEVLDLRTSRDLHYLRESEQRVNSVERRVKTAHNNLQSLSAKGLQ-d...........................
W5KK58_ASTMX/54-153                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMTQSIQTLDQRTQKDLQYVQRMEVQLRGLESKFKQVEESHKQNIAKQYK-a...........................
F6XID5_MONDO/49-147                    ................................QSPEDGWQLYTSAQAPDGKCVCTAVIPAQNSCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTFRDLQYVRNTESLMRSLDSRLRAADG-ARSLSAKSFQE............................
E1BUB7_CHICK/52-151                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
H2SYC3_TAKRU/52-151                    ...............................p-SPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNISQSMEVLDLRTYRDLQYVRNTENLMKVVDGKLKVASENPRSLNPKGFQE............................
F7CTG0_MONDO/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
U3J435_ANAPL/1-82                      ................................------------------KCLCTAVIPVQGSCSRDLRSHQLRQLTE.K.....VQNISQSMEVLDLRTYRDLQYVRNTEALMKGLDSRLRVAAESQKSLNAKSFQE............................
F1R5K6_DANRE/52-151                    ...............................p-SPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNITQSMEVLDLRTYRDLQYVRDTENLMKTVDGKLKTASENPRSLNPKSFQE............................
A0A0D9S6M2_CHLSB/13-112                ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
F7C4L1_CALJA/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
F6V4B9_MACMU/26-81                     ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VS---------------------------------------------------lcrvcvc.....................
X1WFJ9_DANRE/13-112                    ...............................p-SPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNITQSMEVLDLRTYRDLQYVRDTENLMKTVDGKLKTASENPRSLNPKSFQE............................
F7EDG3_MONDO/36-135                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
I3JB54_ORENI/27-126                    ...............................i-GPKEGWQVYSSAQDADGRCICTVVAPEQSLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVMKMENQMKGLRTKFRQIEDDRKSIMARNFQE............................
U3IQ19_ANAPL/4-103                     ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMRGLESKFKQVEESHKQHLARQFK-a...........................
F6WV18_HORSE/36-135                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
A0A0A0MXJ7_PAPAN/25-121                ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQE............................
G3PW76_GASAC/50-149                    ...............................p-GSEEGWQVYSTASDPDGRCVCTVVAPARNLCKRDPRSRQLRILTE.Q.....VQNVSQSMEVVDLRTSRDLQYVRDSEPLLRGVDGRLHTHVANPYSLTTRGLQE............................
H2SYC4_TAKRU/38-137                    ...............................p-SPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNISQSMEVLDLRTYRDLQYVRNTENLMKVVDGKLKVASENPRSLNPKGFQE............................
NOE3_HUMAN/46-145                      ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
K7EIS8_HUMAN/1-45                      ................................----------------------------------------------.-.....-------MEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQElk..........................
G3PWT1_GASAC/1-50                      ................................----------------------------------------------.-.....---MSQSIEVLNLRTQRDFQYIMRMESQIKGLRSKFRQIESDRKTLVNKNFQE............................
G3X9Q7_MOUSE/26-125                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLETKFKQVEESHKQHLARQFK-a...........................
H3AZZ1_LATCH/1-56                      ................................--------------------------------------------ME.K.....VQNISQSMEVLHLRTNRDFQYVKNTDSLMKVLDSKLNVATVNQRNLNKKSFQE............................
A0A091D9E7_FUKDA/46-145                ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
L5L3M9_PTEAL/9-107                     ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRGADG---SLSAKSFQElk..........................
L5LQG1_MYODS/1-53                      ................................--------------------------------------------ME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRAADG---SLSAKSFQE............................
A0A0D9R5L3_CHLSB/1-45                  ................................----------------------------------------------.-.....-------MEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQElk..........................
Q6DBT0_DANRE/26-125                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMTQSIQVLDQRTQRDLQYVVKMEDQLRGLETKFRQVEENHKQNIAKQYK-g...........................
F7HZJ8_CALJA/25-121                    ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQE............................
G1RBX1_NOMLE/36-135                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
G7PR72_MACFA/18-117                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
F6ZCY5_ORNAN/45-144                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
L5K4Y0_PTEAL/46-149                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.KelkekMDELLPLIPVLEQ-YKTDAKLITQFKEEIRNLSAVLTGIQEE-----------igaydyeelhq.................
V8NWC3_OPHHA/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLRMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
H0W0L9_CAVPO/34-133                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMRGLESRFKQVEESHKQHLARQFK-a...........................
NOE3_RAT/46-145                        ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
G1SDG0_RABIT/26-125                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
H2SYC7_TAKRU/13-112                    ...............................p-SPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNISQSMEVLDLRTYRDLQYVRNTENLMKVVDGKLKVASENPRSLNPKGFQE............................
F1MDY6_BOVIN/26-125                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
I3LLD2_PIG/54-152                      ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-............................
M7BG89_CHEMY/54-153                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
H2PZI2_PANTR/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
A6QPI8_BOVIN/26-125                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFRQVEESHKQHLARQFK-g...........................
H2SYC8_TAKRU/1-98                      ................................--PEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNISQSMEVLDLRTYRDLQYVRNTENLMKVVDGKLKVASENPRSLNPKGFQE............................
W5KRL1_ASTMX/24-123                    .............................vrl---KEGWQVYSSAQDADGRCICTVVAPEQNLCSRDAKSKQLRTLQE.K.....IQNMSQSIEVLNLRTQRDFQYVMKMESQIKGLRSKLRQVETNRRTLPTKNFQE............................
G3IJL3_CRIGR/26-125                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
H2MTK2_ORYLA/1-99                      ...............................t--PEEGWQVYSSAQDSDGRCVCTVVAPQQTVCSRDARSKQLRQLLE.K.....VQNMSQSIEALDQRTQKDLQFVEKMEVQLKGLEEKFQQVEDGHESNNVRQFK-f...........................
H2LML3_ORYLA/14-113                    ...............................p-SPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNISQSMEVLDLRTYRDLEYVKNTESLMKVVDGKLKVASENPRSLNPKGFQE............................
H2TBZ3_TAKRU/29-128                    ...............................i-SPQEGWQVYSSAQDADGRCICTVVAPEQSLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVMKMESQMKGLRSKFRQIEDDRKSIIARNFQE............................
W5KHY6_ASTMX/54-153                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMTQSIQVLDQRTQRDLQYVVKMEDQLRGLETKFRQVEENHKQNLAKQYK-a...........................
G3P636_GASAC/52-151                    ...............................p-SPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNISQSMEVLDLRTYRDLQYVRNTESLMKEVDGKLKVASESPRSLNPKGFQE............................
I3JZ46_ORENI/54-153                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQSMCSRDARTKQLRQLLE.K.....VQNMTQSIQVLDQRTQRDLQYVEKMEVQLRGLETKFRQVEENHKQNIAKQYK-a...........................
A0A096N6V8_PAPAN/54-153                ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
H2LEZ1_ORYLA/54-153                    ...............................a-NPEESWQVFSSAQDSEGRCVCTVVAPQQSMCSRDARTKQLRQLLE.K.....VQNMTQSIQVLDQRTQRDLQYVEKMEVQLRGLETKFRQVEENHKQNIAKQYK-a...........................
L5LXH7_MYODS/231-330                   ...............................v-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
K7EKW2_HUMAN/49-147                    ...............................q-NPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQElk..........................
G1SMC5_RABIT/1-53                      ................................--------------------------------------------ME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRAADG---SLSAKSFQE............................
A0A087Y2U8_POEFO/28-127                ..............................sp--PEEGWQVYSSAQDSEGRCVCTVVAPQQTVCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDQRTQRDMQFVERMEVQLKSLENKFKQVEEGHESNIARQYK-s...........................
G3TDJ6_LOXAF/16-112                    ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQTTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRVADG---SLSAKSFQE............................
M4AUA2_XIPMA/3-60                      ............................vfal----------------------------------------------.Q.....VQNISQSMEVLDLRTFRDLQYVKNTEGLMKVVDGKLKVASENPRSLNPKGFQE............................
F7H3M1_MACMU/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
F6V489_MACMU/36-91                     ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VS---------------------------------------------------lcrvcvc.....................
F6U4R3_MACMU/25-121                    ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQE............................
F7CQB6_HORSE/8-104                     ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQE............................
H2LEY7_ORYLA/26-125                    ...............................a-NPEESWQVFSSAQDSEGRCVCTVVAPQQSMCSRDARTKQLRQLLE.K.....VQNMTQSIQVLDQRTQRDLQYVEKMEVQLRGLETKFRQVEENHKQNIAKQYK-a...........................
M7BC92_CHEMY/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
G3PTR4_GASAC/54-153                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQSMCSRDARTKQLRQLLE.K.....VQNMTQSIQVLDQRTQRDLQYVEKMEVQLRGLETKFRQVEENHKQNIAKQYK-a...........................
H2M0G5_ORYLA/1-98                      ...............................a---EEGWQVYSTASDPDGRCVCTVVAPARNLCKRDPRIRQLRSLTE.Q.....VQNVSQSMEVVDLRTSRDLQYVQDSEPLLRGVDGRLHTYVSNPRALTSKGLQE............................
H2MZE3_ORYLA/26-125                    ...............................v-GSKEGWQVYSSAQDADGRCVCTVVAPEQNLCSRDAKGRRLKRLLE.K.....VQNMTQSIQILNLRTQRDFQYIMRMENQIKGLRSRFRQVESDRRTHVSKNFQE............................
A0A087Y5G5_POEFO/3-102                 ...............................i-GPKEGWQVYSSAQDADGRCICTVVAPEQSLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVIKMENQMKGLRTKFRQVEDDRKSIMAKNFQE............................
L8YCC6_TUPCH/56-155                    ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SVSAKSFQElkd.........................
F7EDF9_MONDO/54-153                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
A0A087X9L0_POEFO/52-151                ...............................p-GSEEGWQVYSTASDPDGRCVCTVVAPARNLCKRDPRNQQLRLLTE.Q.....VQNVSQSMEVVDLRTSRDLQYVRDSEPLLRGVDGHLHTYVASPRTLTSKTLQE............................
A0A087XG78_POEFO/23-122                ...............................p-SPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNISQSMEVLDLRTFRDLQYVKNTEGLMKVVDGKLKVASENPRSLNPKGFQE............................
A3KGE4_MOUSE/11-110                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLETKFKQVEESHKQHLARQFK-a...........................
G3NBD6_GASAC/27-126                    ...............................i-GPKEGWQVYSSAQDADGRCICTVVAPEQSLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVMKMENQMKGLRTKFRQIEDDRKSIIARNFQE............................
F1MTJ5_BOVIN/19-115                    ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRAADG---SLSAKSFQE............................
H2RMY8_TAKRU/39-139                    ..............................ir--PKEGWQVYSSAQDADGRCICTVVAPEQNLCSRDAKGRQLRQLLEkK.....VQNMSQSIEVLNLRTQRDFQYIMRMESQIKGLRSKFRQIESDRKTLVNKNFQE............................
C3YEW5_BRAFL/31-129                    ...............................h-GSRDTYYVHSTSEDTSGHCTCTVLAPSPDVCSDDAKYHYIKDLEA.Q.....VANLTTLVHQLANRTSSALD-IQTTMTLIHNLTSQLDVLEADRQLLLTEYF--sg..........................
H2RVD4_TAKRU/27-126                    ...............................s-VPEESWQIYSSAQDSDGRCVCTVVAPQQTVCSRDARTQQLKQLLK.K.....VQNMSHSIDILDQRTKRDLKFVENMEFQLKNMENKFKEVEDDHESNSARQYK-v...........................
G3WPL4_SARHA/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKVKFRQIEDDRKTLMTKHFQE............................
M4AJT1_XIPMA/37-136                    ..............................sp--PEEGWQVYSSAQDSEGRCVCTVVAPQQTVCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDQRTQRDMQFVEKMEMQLKSLENKFKQVEEGHESNIARQYK-s...........................
F7H3M5_MACMU/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
G5AYR0_HETGA/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
F8W870_HUMAN/43-142                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
I3JB53_ORENI/42-141                    ...............................i-GPKEGWQVYSSAQDADGRCICTVVAPEQSLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVMKMENQMKGLRTKFRQIEDDRKSIMARNFQE............................
G1RMV4_NOMLE/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
G1LVY1_AILME/37-134                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESK--QATPSHKQHLARQFK-a...........................
H3CS59_TETNG/19-119                    ...............................p-GSEEGWQVYSMASDPDGRCVCTVVAPARNLCKRDPRSRQLRLLTE.P....vVQNVSQSLEVVDLRTARDLQYVRDSEPLLRGVDGRLHSYVANPRALTAKSLQE............................
G3THR5_LOXAF/4-103                     ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
H2TBZ4_TAKRU/25-124                    ...............................i-SPQEGWQVYSSAQDADGRCICTVVAPEQSLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVMKMESQMKGLRSKFRQIEDDRKSIIARNFQE............................
F6UYR7_CANFA/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
M7BS18_CHEMY/88-152                    .......................arhimgliv--------------------------------------------TH.P.....VQNLSQSMEVLDLRTFRDLQYVRHTESLMKGLDSRLKVATESQKSLNTKSFQE............................
G1KBH1_ANOCA/26-125                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLRMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
H3BGU2_LATCH/26-125                    ...............................a-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIDVLDQRTKRDLQYVERMETQMRGLENKFKRVEESHEQHLARQFK-g...........................
H3BGU1_LATCH/38-137                    ...............................a-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIDVLDQRTKRDLQYVERMETQMRGLENKFKRVEESHEQHLARQFK-a...........................
F6RAY1_CALJA/55-143                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VSLHGQSVEALDRVTPRPGNFV-------------------------------sflergaiaiesdrargare........
G1M0Y6_AILME/25-121                    ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRAADG---SLSAKSFQE............................
H2MTK3_ORYLA/1-99                      ...............................t--PEEGWQVYSSAQDSDGRCVCTVVAPQQTVCSRDARSKQLRQLLE.K.....VQNMSQSIEALDQRTQKDLQFVEKMEVQLKGLEEKFQQVEDGHESNNVRQFK-f...........................
H2QFA5_PANTR/25-121                    ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQE............................
G5B6W4_HETGA/37-158                    ..............................ar--AEDAYAVETVSAGTDCRCSCTAPPASLNPCERDWKMEKLRKQAP.E.....LLKLQSMVDLLEGALYS-MD-LMKVHAYVHKVASQMSTLEESVKANLSR----enevvresmrhlseqlrsyenhsaavls
F5GZQ2_HUMAN/1-70                      ................................------------------------------MCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
A0A091DCH1_FUKDA/1219-1315             ................................QSPEEGWQLYTSAQAPDGKCVCTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRAADG---SLSAKSFQE............................
H2MTK0_ORYLA/19-118                    ...............................s-TPEEGWQVYSSAQDSDGRCVCTVVAPQQTVCSRDARSKQLRQLLE.K.....VQNMSQSIEALDQRTQKDLQFVEKMEVQLKGLEEKFQQVEDGHESNNVRQFK-f...........................
F7HKM5_MACMU/26-125                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
H2SYC6_TAKRU/25-124                    ...............................p-SPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNISQSMEVLDLRTYRDLQYVRNTENLMKVVDGKLKVASENPRSLNPKGFQE............................
B7ZD18_DANRE/16-75                     ...........................mgtel---------------------------------------------T.Q.....VQNMTQSIQVLDQRTQRDLQYVVKMEDQLRGLETKFRQVEENHKQNIAKQYK-g...........................
G3QT74_GORGO/23-119                    ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQE............................
H9G952_ANOCA/49-148                    ................................QSPDEGWQVYTSAQAPDGKCLCTAVIPVQGSCSRDLRSRQLRQLME.K.....VQNISQSMEVLDLRTYRDLQYVRNTESLMKGLDSRLKVASESQKNLNAKSFQE............................
NOE2_MOUSE/19-118                      ................................QSPEEGWQLYTSAQAPDGKCVCTAVIPAQSTCARDGRSRELRQLME.K.....VQNVSQSMEVLELRTFRDLQYVRSMETLMRSLDARLRAADG---SVSAKSFQElkd.........................
G1RMX8_NOMLE/24-120                    ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQE............................
G3P960_GASAC/36-135                    ...............................s-VPEDGWQVYSSAQDSEGRCVCTVVAPQQTVCSRDARTKQLRQLLE.K.....VQNMSQSINVLDQRTQRDLQFLEKMEVQLKGLENKFKQVENGHESNIARQYK-s...........................
G3WZT5_SARHA/54-153                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
W5MK37_LEPOC/50-149                    ...............................p-SPEEGWQIYSSAQDPDGKCVCTVVAPAQSMCTRDPRSRQLRQLME.K.....VQNISQSMEVLHLRTERDLQYITKTGSLVSEVNSKLKVASESTRTLDPKSFQE............................
M3ZEN4_XIPMA/25-125                    ..............................ir--PKEGWQVYSSAQDADGRCICTVVAPEQNLCSRDAKGRQLRQLLEkK.....VQNMSQSIEVLNLRTQRDFQYIMRMESQIKGLRSKFRQIESDRKTLVNKNFQD............................
H9GCE6_ANOCA/1-70                      ................................------------------------------MCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMRGLETKFKQVEESHKQHLARQFK-a...........................
H0WUT4_OTOGA/54-153                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
V8PIM3_OPHHA/14-113                    ................................QSPDEGWQVYTSAQAPDGKCLCTAVIPVQGTCSRDLRSRQLRQLME.K.....VQNISQSMEVLDLRTYRDLQYVRNTESLMKGLDSRLKVATEGQKNLNVKSFQE............................
G7NV38_MACFA/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
Q8R357_MOUSE/54-153                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLETKFKQVEESHKQHLARQFK-a...........................
F7FV23_ORNAN/26-125                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
I3IUH3_ORENI/52-151                    ...............................p-GSEEGWQVYSTASDPDGRCVCTVVAPARNLCKRDPRSRQLRSLTE.Q.....VQNVSQSMEVVDLRTSRDLQYVRDSEPLLRGVDGRLHTYVANPRTLTARSLQE............................
B7ZD15_DANRE/54-153                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMTQSIQVLDQRTQRDLQYVVKMEDQLRGLETKFRQVEENHKQNIAKQYK-a...........................
H0X2N5_OTOGA/5-102                     ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDSRLRVADG---SLSAKSFQEl...........................
M3ZHZ3_XIPMA/25-124                    ...............................i-GPKEGWQVYSSAQDADGRCICTVVAPEQSLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVIKMENQMKGLRTKFRQVEDDRKSIMAKNFQE............................
H2RVD3_TAKRU/26-125                    ...............................s-VPEESWQIYSSAQDSDGRCVCTVVAPQQTVCSRDARTQQLKQLLK.K.....VQNMSHSIDILDQRTKRDLKFVENMEFQLKNMENKFKEVEDDHESNSARQYK-v...........................
F1S3G6_PIG/5-101                       ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRAADG---SLSAKSFQE............................
H2LML0_ORYLA/52-151                    ...............................p-SPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNISQSMEVLDLRTYRDLEYVKNTESLMKVVDGKLKVASENPRSLNPKGFQE............................
F6Y788_XENTR/53-152                    ...............................i-SPREGWQVYSSAQDSDGRCICTVVAPEQNLCSRDAKSKQLRQLLE.K.....VQNMSQSIEVLNLRTERDYQYVQKMETQMKVVRVKFRQIEEDRKTLLTRHFQD............................
G3RJC5_GORGO/36-135                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
I3KQC2_ORENI/25-124                    ..............................ir--PKEGWQVYSSAQDADGRCICTVVAPEQNLCSRDAKGRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYIMRMESQIKGLRSKFRQIEADRKTLVNKNFQE............................
I3MQI5_SPETR/59-158                    ...............................l-NPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
M4AUL7_XIPMA/36-135                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQSMCSRDARTKQLRQLLE.K.....VQNMTQSIQVLDQRTQRDLQYVEKMEVQLRGLETKFKEVEENHKQNIAKQYK-a...........................
V8NTM5_OPHHA/12-111                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMRGLESKFKQVEESHKQHLARQFK-r...........................
R4GEF0_DANRE/51-147                    ...............................p-GQDEGWQVYGSAQ---GRCVCSIKTPVPDACAGDPRHTRLQQISA.H.....VLNVSEHMQLLTRRTAGDLQELRSSETILDTLEKTLTSAQQNPQELSDRSLQE............................
M3YKV4_MUSPF/36-135                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
F6ZCX8_ORNAN/27-126                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
H2M0G6_ORYLA/52-151                    ...............................p-GAEEGWQVYSTASDPDGRCVCTVVAPARNLCKRDPRIRQLRSLTE.Q.....VQNVSQSMEVVDLRTSRDLQYVQDSEPLLRGVDGRLHTYVSNPRALTSKGLQE............................
F1R4X5_DANRE/25-124                    ...............................i-GPKEGWQVYSSAQDADGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVMKMENQMKGLRTKFRQIEEDRKTIMARNFKE............................
G3STF8_LOXAF/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
G1LVW6_AILME/36-133                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESK--KATPSHKQHLARQFK-a...........................
H2UFP3_TAKRU/51-150                    ...............................k-SSEEGWQVYSTASDPDGRCVCTVVAPARNLCKRDPRSRQLRLLTE.Q.....VQNVSQSLEVVDLRTARDLQYVRDSEPLLRGVDGRLHTYVANPRTLTAKSLQE............................
H0WRE7_OTOGA/47-146                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
W5NV91_SHEEP/36-135                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMESQMKGLESKFRQVEESHRQHLARQFK-a...........................
Q6DGM5_DANRE/26-125                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMTQSIQNLDQRTQKDLQYVQRMEVQLRGLETKFKQVEESHKQNIAKQYK-g...........................
G3RLQ0_GORGO/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
F6V4D7_MACMU/23-78                     ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VS---------------------------------------------------lcrvcvc.....................
M4ATN0_XIPMA/52-151                    ...............................p-GSEEGWQVYSTASDPDGRCVCTVVAPARNLCKRDPRNQQLRLLTE.Q.....VQNVSQSMEVVHLRTSRDLQYVRDSEPLLRGVDGHLHTYVASPRTLTSKTLQ-g...........................
W5L727_ASTMX/1-54                      ................................----------------------------------------------.Q.....VQNMSQSIEVLNLRTQRDFQYVMKMENQMKGLRTKFRQIEEDRKTIMARNFK-q...........................
H0Z6H8_TAEGU/54-153                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMRGLESKFKQVEESHKQHLARQFK-a...........................
H2NXH6_PONAB/1-53                      ................................--------------------------------------------ME.K.....VQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQE............................
F1N764_BOVIN/36-135                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFRQVEESHKQHLARQFK-a...........................
I3IWH6_ORENI/30-129                    ...............................s-TPEEGWQVYSSAQDSEGRCVCTVVAPQQTICSRDARTKQLRQLLE.K.....VQNMSQSIEALDQRSQRDLQFVEKMEVQLKGLENKFKQVEDGHESNIARQYK-s...........................
W5MMX5_LEPOC/25-124                    ...............................i-GPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLRSKFRQVEDDRKTLMTKHFQE............................
K7ELC6_HUMAN/1-43                      ................................----------------------------------------------.-.....-------MEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQE............................
W5PVN8_SHEEP/49-145                    ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRAADG---SLSAKSFQE............................
G1L428_AILME/54-153                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
M3YSX6_MUSPF/1-55                      ................................--------------------------------------------ME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRAADG---SLSTKSFQElk..........................
NOE1_RAT/54-153                        ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFRQVEESHKQHLARQFK-a...........................
I3IZI4_ORENI/52-151                    ...............................p-RPEEGWEIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNISQSMEVLDLRTYRDLQYVRNTESLMKVVDGKLKVASENPRSLNPKGFQE............................
NOE1_MOUSE/54-153                      ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLETKFKQVEESHKQHLARQFK-a...........................
F7BXL7_XENTR/1-52                      ................................----------------------------------------------.-.....VQNISQSMEVLDLRTFRDLQYLRNTESLMKVLDTKLRATD-SQRNINAKSFQE............................
D3YTM3_MOUSE/13-112                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
H2UFP4_TAKRU/50-149                    ...............................p-GSEEGWQVYSTASDPDGRCVCTVVAPARNLCKRDPRSRQLRLLTE.Q.....VQNVSQSLEVVDLRTARDLQYVRDSEPLLRGVDGRLHTYVANPRTLTAKSLQE............................
F5H810_HUMAN/1-50                      ................................----------------------------------------------.-.....---MSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
E2RQL9_CANFA/55-154                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
F1S570_PIG/46-145                      ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
H2N6L8_PONAB/26-125                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
F7FV31_ORNAN/27-126                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
W5QAR8_SHEEP/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
NOE1_CHICK/54-153                      ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMRGLESKFKQVEESHKQHLARQFK-a...........................
H2VEA1_TAKRU/54-153                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQSMCSRDARTKQLRQLLE.K.....VQNMTQSIQVLDQRTQRDLQYVEKMEVQLRGLETKFRQVEETHKQNIAKQYK-a...........................
R7PRK2_9FIRM/9-100                     alaklpegskfievikseisrlnneaaaqrid----------------------------------------KKKFES.K.....VKELESTITDLKEKGTGDLSTIEKMQKQLDELQEKYETAENSRKEEKAKRVK-t...........................
F7C449_CALJA/26-125                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
F7CJF2_CALJA/26-125                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
NOE1_HUMAN/54-153                      ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
L5K742_PTEAL/1-70                      ................................------------------------------MCSRDARTRQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
B7ZD16_DANRE/54-153                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMTQSIQVLDQRTQRDLQYVVKMEDQLRGLETKFRQVEENHKQNIAKQYK-g...........................
U3IYJ8_ANAPL/47-146                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
H2MTK1_ORYLA/5-104                     ...............................s-TPEEGWQVYSSAQDSDGRCVCTVVAPQQTVCSRDARSKQLRQLLE.K.....VQNMSQSIEALDQRTQKDLQFVEKMEVQLKGLEEKFQQVEDGHESNNVRQFK-f...........................
C3XRI0_BRAFL/16-114                    .............................iav---QDTYYVHSTAEDNTGHCVCTVIAPSANICSDDSKYQFIKDIQD.E.....VSNLTVLIQQLANRTSSALD-IQTVIGNIQNVTIQLNLLEGNRELLLTELF--ns..........................
H3DMI7_TETNG/53-152                    ...............................p-SPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNISQSMEVLDLRTYRDLQYVRNTENLMKVVDGKLKVASENPRSLNPKGFQE............................
U3JG49_FICAL/54-153                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMRGLESKFKQVEESHKQHLARQFK-a...........................
F7I1T3_CALJA/44-140                    ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQE............................
F6Q7Q2_HORSE/26-125                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
G1N4M6_MELGA/57-156                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
G5B357_HETGA/1-54                      ................................--------------------------------------------ME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDASLRAADG---SLSAKSFQEl...........................
L8YCW6_TUPCH/54-153                    ...............................a-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMETQMKGLESKFRQVEESHKQHLARQFK-a...........................
A2AWU2_DANRE/54-153                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMTQSIQNLDQRTQKDLQYVQRMEVQLRGLETKFKQVEESHKQNIAKQYK-g...........................
U3JIH3_FICAL/25-124                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
H0XV76_OTOGA/53-152                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
W5LWC1_LEPOC/90-189                    ...............................a-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMTQSIEVLDRRTQRDLQYVEKMETQIRGLETKFRQVEESHKQNLAKQYK-a...........................
H0Z3M4_TAEGU/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
A2AWU1_DANRE/54-153                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMTQSIQNLDQRTQKDLQYVQRMEVQLRGLETKFKQVEESHKQNIAKQYK-a...........................
H2SYC5_TAKRU/18-117                    ...............................p-SPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLME.K.....VQNISQSMEVLDLRTYRDLQYVRNTENLMKVVDGKLKVASENPRSLNPKGFQE............................
W5KK57_ASTMX/26-125                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMTQSIQTLDQRTQKDLQYVQRMEVQLRGLESKFKQVEESHKQNIAKQYK-a...........................
H3CC10_TETNG/54-153                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQSMCSRDARTKQLRQLLE.K.....VQNMTQSIQVLDQRTQRDLQYVEKMEVQLRGLETKFRQVEENHKQNIAKQYK-a...........................
B7ZD17_DANRE/26-125                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMTQSIQVLDQRTQRDLQYVVKMEDQLRGLETKFRQVEENHKQNIAKQYK-a...........................
H2TBZ5_TAKRU/20-119                    ...............................i-SPQEGWQVYSSAQDADGRCICTVVAPEQSLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVMKMESQMKGLRSKFRQIEDDRKSIIARNFQE............................
A0A087XKG0_POEFO/1-50                  ................................----------------------------------------------.-.....---MSQSIEVLNLRTQRDFQYIMRMESQIKGLRSKFRQIESDRKTLVNKNFQD............................
NOE3_MOUSE/46-145                      ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
F1P6C4_CANFA/8-104                     ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRAADG---SLSAKSFQE............................
G1PBQ6_MYOLU/5-101                     ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCARDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRAADG---SLSAKSFQE............................
G3P962_GASAC/26-125                    ...............................s-VPEDGWQVYSSAQDSEGRCVCTVVAPQQTVCSRDARTKQLRQLLE.K.....VQNMSQSINVLDQRTQRDLQFLEKMEVQLKGLENKFKQVENGHESNIARQYK-s...........................
A0A096MRZ8_PAPAN/46-145                ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
NOE2_HUMAN/25-121                      ...............................q-NPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQE............................
F1QM40_DANRE/3-102                     ..............................ir--PKEGWQVYSSAQDADGRCICTVVAPEQSLCSRDAKSKQLRQLLE.K.....IQNMSQSIEVLNLRTQRDFQYVMKMESQMKGLRSKFRQIESNRRTLLTKNFQE............................
A0A0A0MV29_PAPAN/22-118                ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQE............................
A4IHX8_XENTR/54-153                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVERMENQMKGLESKFKQVEETHRQHQARQFK-a...........................
H2LLZ9_ORYLA/26-125                    ...............................i-GPKEGWQVYSSAQDADGRCICTVVAPEQNLCSRDAKSKQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVMKMENQMKGLRTKFRQVEDERKSIISKNYQE............................
H2M0G3_ORYLA/52-151                    ...............................p-GAEEGWQVYSTASDPDGRCVCTVVAPARNLCKRDPRIRQLRSLTE.Q.....VQNVSQSMEVVDLRTSRDLQYVQDSEPLLRGVDGRLHTYVSNPRALTSKGLQE............................
W5MK23_LEPOC/23-122                    ...............................p-SPEEGWQIYSSAQDPDGKCVCTVVAPAQSMCTRDPRSRQLRQLME.K.....VQNISQSMEVLHLRTERDLQYITKTGSLVSEVNSKLKVASESTRTLDPKSFQE............................
A0A091CQS4_FUKDA/21-120                ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
H2PTW9_PONAB/52-117                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....CGKLTGISDPVTVKT--------------------------------------sgsr........................
I3M5U5_SPETR/4-103                     ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTFRDLQYVRSMETLMRSLDARLRAADG---SVSAKSFQElkd.........................
G5B8J0_HETGA/4-103                     ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFK-a...........................
I3L7A4_PIG/28-124                      ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRAADG---SLSAKSFQE............................
H0W3G4_CAVPO/9-105                     ................................QSPEEGWQLYTSAQAPDGKCVCTAVIPAQSTCSRDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADG---SLSAKSFQE............................
H3DBM5_TETNG/1-101                     ..............................ir--PKEGWQVYSSAQDADGRCICTVVAPEQNLCSRDAKGRQLRQLLEkK.....VQNMSQSIEVLNLRTQRDFQYIMRMESQIKGLRSKFRQIESDRKTLINKNFQE............................
H2M0G0_ORYLA/1-97                      ................................---EEGWQVYSTASDPDGRCVCTVVAPARNLCKRDPRIRQLRSLTE.Q.....VQNVSQSMEVVDLRTSRDLQYVQDSEPLLRGVDGRLHTYVSNPRALTSKGLQE............................
A2AWU3_DANRE/26-125                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMTQSIQNLDQRTQKDLQYVQRMEVQLRGLETKFKQVEESHKQNIAKQYK-a...........................
U3JG48_FICAL/26-125                    ...............................t-NPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLE.K.....VQNMSQSIEVLDRRTQRDLQYVEKMENQMRGLESKFKQVEESHKQHLARQFK-a...........................
H0VK67_CAVPO/46-145                    ...............................i-SPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLE.K.....VQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQE............................
H2RVD5_TAKRU/38-137                    ...............................s-VPEESWQIYSSAQDSDGRCVCTVVAPQQTVCSRDARTQQLKQLLK.K.....VQNMSHSIDILDQRTKRDLKFVENMEFQLKNMENKFKEVEDDHESNSARQYK-v...........................
A0A093BFQ9_CHAPE/1-52                  ................................----------------------------------------------.-.....VQNISQSMEVLDLRTFRDLQYVRNTESLLRGLDSRLKVAET-QRSLNARSFQE............................
A0A087YA69_POEFO/26-125                ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQSMCSRDARTKQLRQLLE.K.....VQNMTQSIQVLDQRTQRDLQYVEKMEVQLRGLETKFKEVEENHKQNIAKQYK-a...........................
NOE2_RAT/49-148                        ................................QSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCARDGRSRELRQLME.K.....VQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRTADG---SVSAKSFQElkd.........................
H2VEA2_TAKRU/27-126                    ...............................a-NPEESWQVYSSAQDSEGRCVCTVVAPQQSMCSRDARTKQLRQLLE.K.....VQNMTQSIQVLDQRTQRDLQYVEKMEVQLRGLETKFRQVEETHKQNIAKQYK-a...........................
#=GC seq_cons                          ...............................h.sPcEuWQVYSSAQDs-GRCICTVVAPpQshCSRDARo+QLRQLLE.K.....VQNMSQSIEVL-LRTQRDLQYVp+MEsQM+GL-uKF+QlE-s++olhuKpFQ-............................
//
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