GenomeNet

Database: Pfam
Entry: Nse5
LinkDB: Nse5
Original site: Nse5 
#=GF ID   Nse5
#=GF AC   PF08691.8
#=GF DE   DNA repair proteins Nse5 and Nse6
#=GF AU   Mistry J, Wood V
#=GF SE   manual
#=GF GA   25.00 25.00;
#=GF TC   28.10 26.30;
#=GF NC   22.60 21.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   16478984
#=GF RT   The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6
#=GF RT   complex. 
#=GF RA   Pebernard S, Wohlschlegel J, McDonald WH, Yates JR 3rd, Boddy
#=GF RA   MN; 
#=GF RL   Mol Cell Biol. 2006;26:1617-1630.
#=GF DR   INTERPRO; IPR014803;
#=GF CC   Nse5 and Nse6 are non essential nuclear proteins that are
#=GF CC   critical for chromosome segregation in fission yeast [1].  Nse5
#=GF CC   forms a dimer with Nse6 and facilitates DNA repair as part of
#=GF CC   the Smc5-Smc6 holocomplex.
#=GF SQ   52
#=GS J7S707_KAZNA/90-379       AC J7S707.1
#=GS K0K7N9_WICCF/217-302      AC K0K7N9.1
#=GS J8LPK5_SACAR/33-467       AC J8LPK5.1
#=GS Q756F5_ASHGO/1-501        AC Q756F5.2
#=GS Q6FSX3_CANGA/1-531        AC Q6FSX3.1
#=GS E7KML7_YEASL/1-460        AC E7KML7.1
#=GS C5DLY3_LACTC/1-507        AC C5DLY3.1
#=GS A0A0A8KZ96_9SACH/1-203    AC A0A0A8KZ96.1
#=GS H2AT47_KAZAF/1-161        AC H2AT47.1
#=GS G8BTX3_TETPH/2-429        AC G8BTX3.1
#=GS Q6FWW8_CANGA/2-361        AC Q6FWW8.1
#=GS B6JV13_SCHJY/1-562        AC B6JV13.1
#=GS G0W780_NAUDC/68-310       AC G0W780.1
#=GS A0A0A8KZ96_9SACH/200-377  AC A0A0A8KZ96.1
#=GS H2AT47_KAZAF/154-497      AC H2AT47.1
#=GS C5DWA7_ZYGRC/1-507        AC C5DWA7.1
#=GS Q753U0_ASHGO/1-413        AC Q753U0.1
#=GS E7KSD9_YEASL/1-517        AC E7KSD9.1
#=GS C5DLK2_LACTC/150-414      AC C5DLK2.1
#=GS A7TFV6_VANPO/1-559        AC A7TFV6.1
#=GS KRE29_YEAST/1-460         AC P40026.1
#=GS NSE5_SCHPO/2-387          AC O94668.1
#=GS S9VVH5_SCHCR/172-478      AC S9VVH5.1
#=GS E7KBP7_YEASA/1-360        AC E7KBP7.1
#=GS Q6CYC9_KLULA/1-376        AC Q6CYC9.1
#=GS G8ZU95_TORDC/85-396       AC G8ZU95.1
#=GS S6E807_ZYGB2/1-511        AC S6E807.1
#=GS A0A0A8L0T1_9SACH/1-377    AC A0A0A8L0T1.1
#=GS G8ZMA9_TORDC/4-511        AC G8ZMA9.1
#=GS G8JT19_ERECY/1-508        AC G8JT19.1
#=GS NSE6_SCHPO/1-478          AC O13688.1
#=GS E7NLB7_YEASO/1-325        AC E7NLB7.1
#=GS I2H2P8_TETBL/1-516        AC I2H2P8.1
#=GS I2H401_TETBL/8-421        AC I2H401.1
#=GS G8JMX5_ERECY/8-403        AC G8JMX5.1
#=GS G0W780_NAUDC/330-471      AC G0W780.1
#=GS S6EHA9_ZYGB2/94-380       AC S6EHA9.1
#=GS NSE5_YEAST/1-517          AC Q03718.1
#=GS J7RGY0_KAZNA/158-483      AC J7RGY0.1
#=GS C5E4U6_ZYGRC/2-371        AC C5E4U6.1
#=GS E7LTS1_YEASV/1-460        AC E7LTS1.1
#=GS K0K7N9_WICCF/16-114       AC K0K7N9.1
#=GS E7QDU7_YEASZ/1-460        AC E7QDU7.1
#=GS E7LYN6_YEASV/1-517        AC E7LYN6.1
#=GS J7RGY0_KAZNA/1-161        AC J7RGY0.1
#=GS G0W7I9_NAUDC/1-530        AC G0W7I9.1
#=GS J4U292_SACK1/1-507        AC J4U292.1
#=GS G8BZ47_TETPH/6-558        AC G8BZ47.1
#=GS G0VJA4_NAUCC/1-511        AC G0VJA4.1
#=GS A7TR81_VANPO/1-415        AC A7TR81.1
#=GS Q6CWU9_KLULA/1-497        AC Q6CWU9.1
#=GS G0VH93_NAUCC/88-432       AC G0VH93.1
J7S707_KAZNA/90-379                  ...........................................................qveeelhfsqelelhptptllrdklsqqrdnlkqrvkaplv------------------.......--.....------------.-------------------------...------------....--------..-----.--------------------.........---------..-------------------------------------......-----------.---TEYTLDLISKETVSDKYKDWFLFTEGPMDGNNA-----------------AISDT----....-...---...-SLTQLLIQFGATPSSLQSDFIL.......KDEDLEHFDTFCDIYPVDYMMeRIR..PLILSHEDV.GVAT-.-----........RLFTF--.FILDRNVYSSKECTQewCTQVFESLL...SRT.....TVEEFIAQYFA--QLQLHD....RFYflleRLTKLIPPVRIH---------------ILNQLFPK---...----.---TTAVINTFNELFDAQNYKDLLYFV.....................-----------.---------................--LIIFGSDNCNF...........gES.TVAQYFKD............................CILDACEDGA-NGV..ELTI------------.------------------.........------ivgiinvfvk..................................
K0K7N9_WICCF/217-302                 ....................................................................................ldrksyyilrnerfdi------------------.......--.....------------.-------------------------...------------....--------..-----.--------------------.........---------..-------------------------------------......-----------.-----------------------------------------------------AL-QGDGFW....N...AVA...WALQCSS-------TKDNLNLEA.......WNVWKPILELIFDIIEI----.DLD..QFITRKTNN.EDDE-.-----........-------.---------------..---------...---.....-------------------....---....--------------------------------------...----.---------------------------.....................-----------.---------................-------------............--.--------............................--------------..----------------.------------------.........------ngepalfkn...................................
J8LPK5_SACAR/33-467                  .........................................................................................gsifrddddvv---------DDDDDDDDK......vRP.....NFISNTEDDSLDsDEDLS----DLDGDLTLPSAEPNSI..dDF----------....DPILKRSI..LSKRR.APSNDVDGDEEISRTPKKLInf.....vpLKNFNLGQS..FD-TTITTKVTKLRNLNKEILDSPRESTNVVVT-STIt....aKSELQRNIKFV.GNIPEVYLDLVTKETISDKYKDWYFISENCHYEELMDLEMKDMDYSFLYSNSACQDDVPDFI....R...SSF...PSIANLLASFGVNQEKAKLLKID......yGKNENSKYDSLCTIFPVEKML.KFL..MYYYSDDKE.--ERE.I----........FLRTFIC.LVLDRNVFNAMEMEYkiCSKVLELFN...E--.....--EYFINLYLEIVRKDDFF....LHY....RLLQIFPNLQIL---------------LLGRLFDEKEA...RSKT.I--RQSLINKFNELFDYKNYKNLLYFI.....................-----------.---------................--LTIYGSKLIPFg..........pES.QVTEYFKD............................CILDVSNETT-NDV..EISI------------.------------------.........------lkgilnlf....................................
Q756F5_ASHGO/1-501                   ....................................................................................................MNASVGDHDMPSPSEAAV.......PH.....YFVELNEHYLKD.FEQFSSLCSLDEYEQLLYLLEEK--...--FVAGRVAIPP....GDVIVVLL..TLATA.SSHYKADFVRANDPYNVGR-.........-TDIAHRSM..RLLSRLVDAVEEFDDRRYMRFELELLRCQLFLFLDSIv...pkRPEVTIAKRVR.THGKNQPTDIPFAPDEMPLCVD----SLRSASYKYVSVLETKKAVFQNVLLTHVLSQNGGFW....N...CVA...WTLSTMI-------DKDAVKNYC.......GETWFPIVTFLFRLYEL----.RHA..YYMQYEMTQ.GISSA.AYTKEla....dsPLVLLFK.SLGSNNVHITLCDYL..FVNCGKNV-...---.....GRGEARPVYHS--ELKLSA....TYV....PFCKPSTEWKLFKSMQLRRRILSCYFKVLADIPKDHRI...K--P.FSEDQSIKYMVRTLLELETVEMFQAFFftddlk........itmhylpLLAEHIIVVLL.EDCGKAIES................TLVTNLGNL-DVV............IE.NIEEYLEM............................RPVDCSNAIGLHKT..VFYI---DTCTLVLIK.YAILLHGTDVLLTGGLDM........vLKRFFK............................................
Q6FSX3_CANGA/1-531                   ....................................................................................................MSGVSVSVEHVVGNQIGKg.....lPH.....YFVELGDKDITS.FETQNSLYRAEDYDHLLFCLEERWQ..dGDSAFDPLFVPS....FDIIIVLF..TLITV.SDHYKATVLTRNEPYNVNR-.........-VSYSKRAI..KILRKYLRILQQFDTTRYGTYKLELLRCQMFLAIETV......NPHFKYLQNCR.SVKNSTNENVYYKPDAMP--ENIIRRGIVNPYRSFISCVETKNPIFGNIPVNFKLSQRGGLS....N...AIL...WTLANSI------QEDDLLFHDA.......YEIWIPLFDIFISILEI----.RQA..YFLENEIVK.KISKE.LRIQKlm....esPICQFLS.FVDSINFNPLFCEYV..FVNCDYTLI...NRD.....AALTIQPVYKG--ETQPTE....VYY....QRVKYTKQFKAKVSMRIRRRFISLCFNILGSVPTGLHL...PKPR.IHKKRLLVEMSRTLSTFQNIVEFEEFFtfdy............eefmfHLIERTLYELF.KQDRRTIVTe.............rpSLISGKDDL-KTF............FN.EILALFKAgaftpdv.............ringlpphEIIDNAGHVKNEK-..-LRLQKIDVCICTILR.NVLQGQAKPLLVDCKKLL.........IK----vskrini.....................................
E7KML7_YEASL/1-460                   ....................................................................................................MGSVNSSPNEEFETVPDSqi...sgFDsplipTSVGSYFRDDDD.DEKVHPNFXSDPENDSLNSDEEFSSlenSDLNLSGAKAESgddfDPILKRTI..ISK--.RKAPSNNEDEEIVKTPRKLVny.....vpLKIFNLGDS..FD-DTITTTVAKLQDLKKEILDSPRSNKSIVITSNTV.....aKSELQKSIKFS.GSIPEIYLDVVTKETISDKYKDWHFISKNCHYEQLMDLEMKDTAYSFLFGSSRSQGKVPEFV....H...LKC...PSITNLLVLFGVNQEKCNSLKIN......yEKKENSRYDNLCTIFPVNKML.KFL..MYFYSDDDN.DDVRE.F----........FLKAFIC.LILDRKVFNAMESDHrlCFKVLELFN...E--.....--AHFINSYFEIVDKNDFF....LHY....RLLQIFPHLQSA---------------LLRRRFSEKQG...RTET.I--QQNIIKEFNEFFDCKNYKNLLYFI.....................-----------.---------................--LTMYGSKFIPFg..........pKC.QVTEYFKD............................CILDISNETT-NDV..EISI------------.------------------.........------lkgilnlf....................................
C5DLY3_LACTC/1-507                   ....................................................................................................MSILSHGSEKVGVP----.......--.....YNVGLTTESLSV.FEVLNSLCVVENYDQLLYYLEAR--...----RSALAVPP....ADVLIVMM..TLSVI.PDFGAATLEAEMDPYNVGR-.........-ASLATRSI..KLLRHFTDILLSEHAEEENHYSLALLRSQFFIMLDQLslrgitSTRVRERDFTK.RRKTNSGVLLEASPSIFRDDQSPPLLSFKNPYPSYVSCLEHRPEVLKNMPITSKLSQEGEFW....N...CVG...WALYASL-------SDDSHIYER.......SKVWFAVLSVLFDAFEM----.RNK..YSIDSETDP.TANNA.ARLSFie....rsPLVALFR.SLNSQGLIQAFCDIL..FLGCSYEL-...--A.....GKLRVHCVYPK--ELMQVD....TYV....PKLLARTSCKFTQSMSFRHRLLSLFLTMLRSIPEGVEF...SKPC.LSEAGFVRHLGKVLSSFEDTSQLKQFFsvtnpy........efldympLFAQAAANESL.KAFDANYTL................SLVEKLANN-DLV............IE.ELGNVFEAg..........................fPPLDENYDSRPEQF..YSSIEKCDIFLLVILR.YWEYIHGAQLKMTRMRCA.........IRAL--sv..........................................
A0A0A8KZ96_9SACH/1-203               ..................................................................................................ma--TCSH-TYDLGPNQLNK.......PE.....YYVELTEKHLSD.FEIWNSLCSNERYDMVLYLCEQY--...--LNRKVLPVIP....SEVITVLF..TVASI.GDYNKGTLIRKADPFDNGR-.........-ESLSNRCL..RLLETLVNALHEYDTSVYDLHDLELLRCQFFYFVDSIe...pkNGRALILDPIN.DRNSSTTPRRPFKY-LSPSFYDDSPLFAKPLYGSYINLIEDGNMV-----------------....-...---...-----------------------.......---------------------.---..---------.-----.-----........-------.---------------..---------...---.....-------------------....---....--------------------------------------...----.---------------------------.....................-----------.---------................-------------............--.--------............................--------------..----------------.------------------.........------neyl........................................
H2AT47_KAZAF/1-161                   ...............................................................................................mtsct-----RSINHVNGYKDEK......lPH.....YFVEVTLKDLNN.FEILNSICLLDNFDQMLYFLESQINtiqMKDGKRILAIPS....YDVLIVLI..TLATV.SEHSKEQLLRASDPYNFTR-.........-IPLNKKAL..SIIEHYLSILKNFDTTLYAGYDLELLRCQFFLMVDNL......LP---------.--------------------------------------------------------------....-...---...-----------------------.......---------------------.---..---------.-----.-----........-------.---------------..---------...---.....-------------------....---....--------------------------------------...----.---------------------------.....................-----------.---------................-------------............--.--------............................--------------..----------------.------------------.........------ksfnqlesi...................................
G8BTX3_TETPH/2-429                   ..................................................................................................sn------------------.......--.....SFIHDSQDSSVT.DDVLRENIKINN--SIVLSSDSS--...-DSDLDSSFHIDv.gnDPILKTLK..SRQKS.INQEESNVLNLAGNNLFKQV........kIQQFDLGSNfdKNITKNLTVLNNESMASDGIND-NLLQANTFVSQAEIdt.kklISFLGKSTLKK.YHNIEYYINMLVNERVSSKYLDWFFFNQDSTITDIS-------DIISNADFFLLGNNWPKLK....E...LILkkyPTISDLLMSIGVSNEKLERLGDGn....clQLTTDRTYDPLAKLLPFDSVL.QII..AFYCHEKG-.-----.-----........FLKIYFA.IMLDRNFYELSNSYDnnLYDFLKIFS...N--.....--EQILDSYFQLVSKDDYF....MHY....RFSRMIPQYKNI------------LVNYLWKTDSDNID...E---.--SLEKLANEFNNLYDNSKYESLLYYI.....................LF---------.---------................----IYGSDLLPIkmsvekdmisvnHN.NLKEYFIN............................CIHNSTGHLT-NDV..ELPL------------.------------------.........------iknilg......................................
Q6FWW8_CANGA/2-361                   .........................................................................etvfdsendeplvelsdvddfefedgd------------------.......--.....------------.-------------------------...------------....DPILKKMK..L----.DVKPESSSDSE--------G.........EVVLQETDV..HPYMDFLQKLNKIQAGEVGEKRDIKRDKSIVELQHEE......LVKQLKSAGTF.TSVPDRLIDHISSEVLSDKFRDWHFITQECRDIDNT--------------------------....-...---...-TLSSMLDAFGVGNSADLLNLKI......iASEYTKKYDSLSTIYPVGYML.EEL..VDYYRRTLP.RAETP.LE---........YCHAFFL.FVLDIKIYDSHECDTswCEEVLDILT...QRF.....RQEEIFDVYLKVVELNDYY....MHY....RVTKLIPRMKSY---------------ILAKLFGTVD-...----.---TVTIVNEFNTLLDDKRYKELLYFL.....................-----------.---------................--LLVLGTRYVPR...........gKN.ETIKYFIS............................CVTDVYDDSQ-SNP..EISIIKNYLLVLQVL-.------------------.........------df..........................................
B6JV13_SCHJY/1-562                   ....................................................................................................MASQHFSDAEIPDSQSSSgs...stPS.....SPTSSPSSASST.SEALPAVSALLPTASRVRTRSARLRakrRCLPTRSYVWS-....LDRLSKSA..VKDAT.LSHRRKNVIQKLTHYGSAQSqg.....trVASVEKAIL..KNLGMNESVLSSIKAEQDTQDAASEFHYSYVGVVATG......EKSLWSSPKEE.GRESSPVDVSSLSPSDVADFVCSGLLSFEDVVSQIF---------------TRFFENKGANC....E...EWA...VCLQRCLDKLSSSSTKPILLPYI.......SS----VLQAVVDMLGIDVGK.RHT..PVAHDSVRP.PASTA.PSNYSva...atvKLLTLLY.PLCELPLQKDIVADL..CRIALDTAV...SDD.....VRLVIMDAFASILKVPRAT....HSR....TRSRSSDDAWQILYETTTNAQAWVTLLMLLPNRKGIIR...NRQK.LALSWFLSKPLQSINNNNDNASLFAEV.....................CEAIEALPNKT.AEDFVRVRYs.............isALFFAFHGELAPQ............PD.EVLRLLAL...........................lRKLDHSIHGTTTDS..LMLLRCEAKDVVQRLYlYVYYEHCNAYQVLEQAADmnmnvsaadL-----qddiiaptakseavtagdikvavkdnleaeteeepksevkaeak
G0W780_NAUDC/68-310                  ..................................................................erkkrkrinplgylnnkskfipikqfdlgknydt------------------.......--.....------------.-------------------------...------------....--------..-----.--------------------.........---------..----KIVSSMEKLNELIDLANNSPIKSSVVDLAFDKS......KKTYEERLKLVgTRINDSLIDMILKEHISFKYKDWHFIDTNYDPMIISEIFDDDELTFF----NLNKLKIAEMI....K...LKI...PNLNEFMIKCGCNMTKLNSLRISstlsennVIETFNQYDNFVEICPMEDIM.KFL..CYYDDDPN-.-----.-----........FIKIFIC.FILDRKVYETLFLDSicCTNIYQN--...---.....-------------------....---....--------------------------------------...----.---------------------------.....................-----------.---------................-------------............--.--------............................--------------..----------------.------------------.........------vilkrtpqq...................................
A0A0A8KZ96_9SACH/200-377             .................................................................................................ney------------------.......--.....------------.-------------------------...------------....--------..-----.--------------------.........---------..-------------------------------------......-----------.--------------------------------------------------------------....-...---...-----------------------.......---------------------.---..---------.-----.-----........-------.---------------..---------...---.....-------------------....---....--------LRMELSMCLRKDILCLFLKSIRSFEN--IP...VSPP.LTHELFYDAITDTLYNDLKIGNFKQFLitwdle........edrdilaTFIEKIINKAF.SSVESKRKF................KIVSKLSDV-DAI............TN.ELTILLRG...........................mGKFAAFNRSPNSKR..RMQL---DFCILLLGK.-LIVASHPSERFD-----.........------rfhkflftikssgkssvglkd.......................
H2AT47_KAZAF/154-497                 ..............................................................................................sfnqle------------------.......--.....------------.-------------------------...------------....--------..-----.--------------------.........---------..-------------------------------------......-----------.--------------------------SITNPYTAYFTLLKQKETILGNRLLNVQLAKPSEFL....N...LIL...LTLSYSL------EETEGKYLSF.......HERWGPMMDILTDLISL----.RHK..YYMKNEIAKeKIKSS.LYTQRls....esPLACFFK.LFNTFAFKDRFTEYI..FIGCNIKGI...AADrsnkySSFNPHTIFKG--EDAIST....TYV....ARTAFSTAYKVKKSMRLRRRIINKCFKLLSQVPKRHRL...VSPR.MDIDDIITNISITLSNFSNLMEFFAFFdtesps........kdfsflpVVAENTLNELL.FRLESNEGAkeefylsrgqgnditvNLVSNLSNT-DAF............LK.ECLMLLEE............................-KLSTNDSLK---T..PLLIQKSLICILSLLR.FLMFLNDK----------.........------eamr........................................
C5DWA7_ZYGRC/1-507                   ....................................................................................................MGCECSAEFVKGKNGEGF.......EH.....YHVELTESMLNG.FEVLNSMCLLNNFDHLMFFLECQM-...-GPSSCELVVPP....FDVFIVLM..TLVTV.SDHYKDESLRANDPYNVSR-.........-LSLSQRSL..KVLQFYVKKLNEFDVEKYGRYQLELLRCQLFIAYDSIs...pgSDKFYRKKKLR.RTGSGRLFD-----------NDFPTVEFKEPYKSYISCLDQKQEVLGNTLLNLKLNQPGEFK....N...MIL...WTLSNSM------QSQQVLYLAS.......HNVWMPLLDLLLDILTL----.RYD..YFVKNEAER.DDDNK.-YVQQls....scPLALFLR.VFESIQFSSVFCECV..FSNCDYELD...DTL.....TALKIHPVYHG--ETTLSN....TFH....PRVKYTDSYKIRKSLALRRKLLGVCFELLTEVPNGHRL...IYPR.MIPEDISSRIAVILVNFKNLEQFKAFFsnnmdk........rpsyvlaYIVDDTLLEMF.KKFGRKPLKk.............seIGILADSHDVDTL............FK.NCKYYIES............................GLFAPWDSKNPEKS..YLDIQKADTCLIVSMK.-CYAKNGDAVNISNKKEF.........LKALL-e...........................................
Q753U0_ASHGO/1-413                   ....................................................................................................MNAEQGDFVDDSQDEDDQiipvglsESd...aSEVHNMINSDLS.DAISSLDDERDSDWENGTGEEFENS..vAN----------....DPILNKVI..SSRVH.ESTPVPPINREVGAREATLEqi.....raSQMREQIDR..SLIDNI-EKLERLQKQINSSPEKPWLRSTDVVE----......ERRQAISAKIV.NPVPKRLLEYLARD-RVGSNKDWYFLTHNAIYQEPT--------LTELFLGSRPLL------....-...---...-SIRDLYLQFGASEDALDAEFKIl.....eCN----SYEQLNNRAPLELMC.YEI..ERHIPFSAN.DQLEL.-----........SLRYFIL.FILDRKVFDCVELDTewCATLWEKHK...---.....-AIDRIAVYLSVVPKDCYF....LHY....RATRLLP-LKDE---------------LLCKLFIGSQ-...----.---PQEVIKQFDTLLENDDWFQILYFM.....................-----------.---------................--LLVNGLPDYPLg..........gI-.RIWQYFKD............................RIYDMNIDNV-SSI..ELSLLK----------.------------------.........------syvnmctsyk..................................
E7KSD9_YEASL/1-517                   ....................................................................................................MDGALINSVLYVSPRNGA.......-H.....YFVELTEKHLLA.FEMLNSMCLLENYDHVLLFLECQ--...-FGKSHNLAVIP....FDIILVLF..TLSTL.SEYYKEPILRANDPYNTSR-.........-ETLSRRAL..KLLQKYLAILKEFDSEQYNLYDLELLRCQFFLAIDTL......TPKKQKWSFDR.FRRTKSEKGVTYRQNASVDPELDQAKTFKNPYRSYISCLEQRNTILGNRLLNLKLNEPGEFI....N...MIL...WTLSNSL------QESTPLFLSS.......HEIWMPLLEILIDLFSC----.RQD..YFIQHEVAQ.NVSKS.LFVQRls....esPLAVFFE.SLNTRNFANRFSEYV..FLNCDYKLP...SDN.....YATPVHPVYNG--ENTIVD....TYI....PTIKCSPLYKSQKSLALRRKLIGSCFKLLLRVPDGHRL...ITPR.IVADDVIQGISRTLASFNDILQFKKFFmtenls........qesyfipLLAEGTLSEIL.KDTQECVVI...............lTLVENLSDG-VSF............CN.EVIGLVKSk.........................cfAFTEQCSQTSYEEA..VLNIEKCDVCLLVLLR.YLLHLIGTEAILDAKEQLe.......mLHAIE-k...........................................
C5DLK2_LACTC/150-414                 .........................................................................................aasasdkkppl------------------.......--.....------------.-------------------------...------------....--------..-----.--------------------.........---------..-------------------------------------......--RKQVASSFK.QKVPRAYLDMILAENSSRKFQDWYFMTENAQPAEID--------PWATFLGAKKPKKQ----....-...---...-SLKELLKSLGVPSQHLSPQ--L.......QHITVDMYDTVNLLQPVHVMC.KQL..QRYYKCRG-.-----.-----........FAQSFIC.FILDRNVFNSPECTSawCEDVYSRLD...A--.....--NHFTDTYLQLVAGDSYL....LHL....RVSRQIPEFHEL---------------LLEKLFPQHT-...----.---YETLLGEFDRLLKAKEHQKLLYFT.....................LFIYGTATMPF.GD-------................-------------............--.--------............................--------------..----------------.------------------.........------taasqrlrdsvygagndgnhvelviirsyi..............
A7TFV6_VANPO/1-559                   ....................................................................................................MNYAEPCSTSNEFTNKNDik...slPY.....YFVHLTDKHLSN.FETLNAMALIGNYADLLFFIESY--...--ETSDTFVVPP....YDIIILLL..TLVTV.SKYYKEATVRKNDYYVLTG-.........-KQLNKRSI..AILKNYIEILNEFDCGKYDRYSLELLRCQFFLAIELIf...nkEKRTDIRNRFK.RRRAEVEFEIEYLTSSVDENNDDDTIGFQNPYNSYIPFLDRNKTVLGNKLFNIVLNKRDSFI....N...LLI...WTLSNSL------EEDTALYLSS.......QEIWMPILQMILDIYLL----.RHD..YYIQNELTN.KGNSH.FFSREls....rsPIGTLLR.SIGEVDFIERFCESV..FINCSDRND...ILS.....YRTVMQRIYQN--ENVISN....AFL....PRVKYSNDYKMLKSMSIRRKMIGLCFRLLQDLDDDERL...ELPK.MSTNTLGDSIIRCVINFDNIKQFKMFFytemis........kelfflpILAEDCILKLS.ENYLENNREt..............lDLCSNFNNS-KAF............FQ.ILVELINDgyfyipelkcndndaydksnnkekndenNKIDAKIKKSLYKK..YITIMKADICLIVLLR.FFIYENSNMNEIKALSSFn......nfLARV--kkldserlne..................................
KRE29_YEAST/1-460                    ....................................................................................................MGSVNSSPNEEFETVPDSqi...sgFDsplipTSVGSYFRDDDD.DEKVHPNFISDPENDSLNSDEEFSSlenSDLNLSGAKAESgddfDPILKRTI..ISK--.RKAPSNNEDEEIVKTPRKLVny.....vpLKIFNLGDS..FD-DTITTTVAKLQDLKKEILDSPRSNKSIVITSNTV.....aKSELQKSIKFS.GSIPEIYLDVVTKETISDKYKDWHFISKNCHYEQLMDLEMKDTAYSFLFGSSRSQGKVPEFV....H...LKC...PSITNLLVLFGVNQEKCNSLKIN......yEKKENSRYDNLCTIFPVNKML.KFL..MYFYSDDDN.DDVRE.F----........FLKAFIC.LILDRKVFNAMESDHrlCFKVLELFN...E--.....--AHFINSYFEIVDKNDFF....LHY....RLLQIFPHLQSA---------------LLRRRFSEKQG...RTET.I--QQNIIKEFNEFFDCKNYKNLLYFI.....................-----------.---------................--LTMYGSKFIPFg..........pKC.QVTEYFKD............................CILDISNETT-NDV..EISI------------.------------------.........------lkgilnlf....................................
NSE5_SCHPO/2-387                     ...............................................................................................nsalk------------------.......--.....AIIELCIEEDLL.PKSLDVLEYLLSTTSIPIP------...------------....ACYIRMCI..TLLVH.PEYPTSSNIQE-------SCnw.....ilQQVVENRSK..INFDAWSFENDLSDNDMPKENYLKIFSNQCLFTQDVDy...wdLIAYMSSRPPD.LERWMSLMDIWLRILEIDAEENGSALMKKYMGEDLCELQDAIRICFSCFTLPQQTMES----....-...---...-PFATSMSKAPAKTESRGSN---.......------SFEGTSRLANLGA--.---..---------.-----.-----........KLLCLIW.AMLPKGRF--FVVHLtdAFHFLSKLD...ERF.....SKLNAKQQDLFFGNLGASN....LRY....CLSQYI---------------------LMKGIGIGINI...RHTR.CEFTKQLTQLLPTSLPKNKIRQKLHLR.....................-----------.---------................AWVSFLGSALRES............DR.NFDKELFY............................TTLKQLYTMYQQTE..LVGIDRPMAILKDM--.------------------.........------lvlldiskklsldki.............................
S9VVH5_SCHCR/172-478                 ........................................................................................fevvacsnlipp------------------.......--.....------------.-------------------------...------------....--------..-----.--------------------.........---------..-------------------------------------......-----------.-------------------------------------------SIISCVLVYRFFN---SFYspprS...TWL...ECLKTYL--HSNIQSKRDSGLDV.......NF----FYRQVCQKVGFNTQK.RYQ..SVRSETISP.KEVCS.IVLNDssdvnffvQCCQLMY.PICPQKLQSIIVQDV..FRCLLDIK-...---.....VGHSCRLSFMKFMELTITSekphFFY....DLVRLSD-------------QPPVWVSILSSLPSNSPRvvhFRTN.LAIHWFLGTLPEP---AFILSSICEQL.....................----DTLLDRCrNEDYTDLLFl.............tmTFSYTVAGLDLKR............SE.NLSLILEK...........................lRKLNLAIPGTTEHL..LLSRCEVKDYIHRLYM.VIYYENSDVY--------.........------selerti.....................................
E7KBP7_YEASA/1-360                   ....................................................................................................MGSVNSSPNEEFETVPDTqi...sgFDsplipTSVGSYFRDDDD.DEKVHPNFTSDPENDSLNSDEEFSSlenSDLNLSGAKAESgddfDPILKRTI..ISK--.RKAPSNNEDEEIVKTPRKLVny.....vpLKIFNLGDS..FD-DTITTTVAKLQDLKKEILDSPRSNKSIVITSNTV.....aKSELQKSIKFS.GSIPEIYLDVVTKETISDKYKDWHFISENCHYEQLMDLEMKDTAYSFLFGSSRSQGKVPEFV....H...LKC...PSITNLLVLFGVNQEKCNSLKIN......yEKKENSRYDNLCTIFPVNKML.KFL..MYFYSDDDN.DDVRE.F----........FLKAFIC.LILDRKVFNAMESDHrlCFKVLELFN...E--.....--AHFINSYFEIVDKNDFF....---....--------------------------------------...----.---------------------------.....................-----------.---------................-------------............--.--------............................--------------..----------------.------------------.........------ftl.........................................
Q6CYC9_KLULA/1-376                   ....................................................................................................MLSNDEDEVVASSDDGLY.......--.....AKIWDIRDEELD.DNGKNSDHFSDPGESFLLSSDDAML...PT----------....DRVLNNIM..SSNAHiGTKRRRSTDRE--------Kl......weEWHKSLKSS..MEINNMTMELKSFTDKRPDVQASQRKNSPHY------......DRQKQIAYSIK.RNIPTSLLTELAAD-VSDSTVDWYFLREDPDFSVVP-------SRYSTFLGKRLSI------....-...---...-PLDDLYKKFGADLRANIEYTNC.......---------PYGKLIPVETMC.GLI..ESNNSDSVQ.-----.-----........AFKHFIK.FILDRKISGNLKTKW..VINMWNRFT...---.....--CDKLSVYFEVTPRNFYL....MHY....RLTRLIP-IESE---------------IVSKLFPN---...----.---DNDVITEFENLLDSQEWTSLLYFI.....................-----------.---------................--ILVLGTSALPF...........gPS.PRMTYIKD............................CILDLNSQNS-SKI..QLSIIKAYLTV-----.------------------.........------cskit.......................................
G8ZU95_TORDC/85-396                  .....................................................ksydlgrhfdpristsldkvqaltrlandlpvksesktifegkvpaf------------------.......--.....------------.-------------------------...------------....--------..-----.--------------------.........---------..-------------------------------------......---------KN.RDVSSHYIDLILKESISKKYLDWHFITENTQFEEQP--------------PSSVLFGPDENL....F...KRY...PTLESLLVAFGVGRDTLDFIFMEk.....sPLTNSRQNDTLCKLSPFDTMI.NAF..ACYQDQTEQ.-----.-----........FAKYFIC.FILDRKVYESMFCDTiwCSKIYKTF-...---.....SADDFMQQYVSLVHSQDYF....LHY....RLIKLIPAAQDL---------------LIRRLFSEGEF...L-AG.EQARIKLVQEFNDLFDKRRFQQLLYFV.....................-----------.---------................--LTIYGSKYMPF...........gDT.DVTLYFKD............................CIADLFNASA-SDV..ELSL------------.------------------.........------lngflsi.....................................
S6E807_ZYGB2/1-511                   ...................................................................................................m-GYADS-VEFIKGNNS-Vg.....lAH.....YHVELTEAQLGT.FETLNSICLLDNFDHLLLFLECQLY...---DGLNLTVPP....FDIFLVLL..TLATV.SDHYKDHSTRSNDPYNASR-.........-APLNKRAL..KILFFYLERLKEFDTGKYGRYELELLRCQLFLASDSLs...pqRKRFDRPRKLR.KTVANTVYS----CEVVDVGEN----DFKEPYKSYISCLGQKSTVLGNRIINSQLSYPGEFI....N...MIL...WTLCNSM------QDHPALYLAS.......HDVWMPLLGIILDLLEL----.RQD..YFVSQESQA.KNMRK.AEYVQkl...sqsPVAVFLE.SIDSLQFTDLFCEYI..FSKCDYLSA...NNG.....REALVHPVYHG--EATLSN....TFH....LRIKYTKSYKIQKSIALRRKLIGIAFKLLSEVPSGHRL...VYPR.MEADDMINRISVILSEFNNLEQFRAFFsgnpt..........ssyflpLLAEGTLLQLC.HTYKNTSDPl.............swVIISDLLSGADAF............LD.KCISILET............................GLFIPWDNETPQDS..ILDICKADTCLLVLIKtFV----------------.........------rlsgvalgsakfeamlsavkkv......................
A0A0A8L0T1_9SACH/1-377               ....................................................................................................MHSTDEDEVVHSSD--DD.......TH.....DKIWDLQDEDPG.PNGVNSRKFYANRDYFLPSSDDP--...-D------MFQQ....DKVLSSIT..SSNSSsGVKRRGSAEHE--------Kl......weGWHKSLKSS..TRINEMTMEMKSFSEVRLNEQALRRKNSPLH------......DRELQIADSIK.RPIPSSLLRELAAD-ISDTTLDWYFLREDPDFGVVP-------DRIS-----TFLGKNG---....-...--S...VPIRDLYKKFGADCSIDIGDSYC.......---------PYGKLIPVETMC.SLI..KANNTDTAD.-----.-----........SFKCFIK.FILDRQISSNLSASW..VRDIWESFS...---.....--CDKIALYLEVVPRNRYL....LHY....RITRLLP-LQED---------------IVSRLFPK---...----.---DDGIITEFENLLDSHQWTYLLYFI.....................-----------.---------................--MLVLGTSALPF...........gPS.AHMTYIED............................CILDLNTQNH-SQI..QLSVIKSYITVC----.------------------.........------skik........................................
G8ZMA9_TORDC/4-511                   ...............................................................................................gianh--------TSIGENDDER.......LP.....YYVDVSDDTLFT.FEVLNSMCMLDNYDHLLFTLECQS-...--VDEEKFAIPP....FDVLLVLM..TLTTV.SDHYKEPILRQNDPYNTSR-.........-GKLSRRAF..KILRFYVKMLQKYDLNGGQRPDIELLRCQFFLIIDSL......SSNARWARPHR.RKRRKTENGVIYNF-DVAEAEDSELGNIIANPYPYVSCLEQKKSILGNDLLSIKLKQPGSFI....N...MIL...WTLSNSL------QEDNVLYIDN.......HEVWMPLLELIVDLFVL----.RHD..FFIKHELKS.AIDDY.HMVQLls....esPLANFLH.LIDSSQSGISFCQCI..FLSCDYKFD...DLD.....VSIELHPVYYG--ENTLSK....TYI....PRTSFSKVYKLKRSMSLRRKIIGTYCKLLTEVPTGHQL...IKPK.PSADELIKNLSYSLAKFNDIDEFEAFFltgdlt........vasyfvpLIAEDTLCHLF.SNFKKSIERldik........hvalTLVENLDNI-GAF............LY.ECTCFFDK...........................gFFVPPERQIK-SIE..LVEINKADICMLALFQ.YIK---------------.........------fleggeviksnsk...............................
G8JT19_ERECY/1-508                   ....................................................................................................MAASSH-HYVVGSNDAGL.......PH.....YFVELNEQCLKE.FEQYNSLCSVDEYEQLLYLLENK--...--FLSGQVPIPP....SDVIVVLL..TLATA.SSHYKDHLIRGNDPYNVGR-.........-TDIAHRCM..RFLNELLRTVHVFELHKYELFELELLRCQLFTFLDSId...pkQSTSTISKRVR.TRTNNQVSDIPFIAEELPQSLG----SPETVNYKYISALETKKAVFHNPLITRVLSQSGSFW....N...SVA...WALSSSV-------DDDPVKHYC.......GEVWLPIIMFIFELYEL----.RHE..YYKLHELGG.TDRLG.FTQKFi.....rsPLVSLFK.SLSSSNIHIALCDHL..FVNCGKGVG...S--.....--GIARPVYHS--ELNLSA....TYL....PICKPSTSFKWYKSMKLRRRILGAYYRVLADIPSSQRI...K--S.FSEDQSIKYMSRILLQIDKLSMFESFFltdeis........atmhylpLLAEHTVVQLW.EDCNKTIEP................TLVDNLKNL-DAL............ID.NFEDLLEG............................EPKVCVNDLGLLKT..TGYI---YTCTLVLLK.CALFLHGKRLKASRLRSV.........IQRFI-kmesesisatk.................................
NSE6_SCHPO/1-478                     ....................................................................................................MNASNNISKFPDLDNSSK.......--.....-----LIDHILD.SDDSEELDELPDISSLVPSARAQSRkqyLKNDSSNSSTYRw..nIDLLSSTA..TIDDS.VAKRRKLAVQNLLQYDSTQ-.........---------..--TFQTGDEIDELIGKSVGSNVLNVLRSNPIYDDDL-......RYEYCSNSKAR.VPDWNTLKAECLKDNDLEFNEGIIPTTFGDLLSAKLVPLDIALSICS---LQFFRSLGDTTC....S...EWI...ANLEKIFYSYKSSSNNLNQIVRF.......------IFETTADMIGIDLAK.RQV..PIQLERTSA.SENLK.SNLKI........KVINFLK.CCGTLYRFSDDTVRFemIQDACRILI...DNQ.....VGSFCKWQFSQFMELPISL....NPD....FLISNIHKVSES---------PRVWVTILSSLSRSCQK...FRKK.IAFTLFVGKQSKN--DDSDFSSLCQRL.....................----DEISASC.NNDYTTLLYq.............irTFGYAVDEKHFKT............NE.RLECLLEK...........................lRKIDLTISGSTDHL..LLSRCEVKDCIHRLFMvLYYLNTNSAPELERI---.........IE----sdlp........................................
E7NLB7_YEASO/1-325                   ...................................................................................................m------------------.......--.....------------.-------------------------...------------....--------..-----.------------XQYNTSR-.........-ETLSRRAL..KLLQKYLAILKEFDSEQYNLYDLELLRCQFFLAIDTL......TPKKQKWSFDR.FRRTKSEKGVTYRQNASVDPELDQAKTFKNPYRSYISCLEQRNXILGNRLLNLKLNEPGEFI....N...MIL...WTLSNSL------QESTPLFLSS.......HEIWMPLLEILIDLFSC----.RQD..YFIQHEVAQ.NVSKS.LFVQRls....esPLAVFFE.SLNTRNFANRFSEYV..FLNCDYKLP...SDN.....YATPVHPVYNG--ENTIVD....TYI....PTIKCSPLYKSQKSLALRRKLIGSCFKLLLRVPDGHRL...ITPR.IVADDVIQGISRTLASFNDILQFKKFF.....................---------M-.---------................-------------............--.--------............................--------------..----------------.------------------.........------tenlsqesyfy.................................
I2H2P8_TETBL/1-516                   ....................................................................................................MQCSSSQSFVLGKERKNN.......PH.....YFVDLTEDILNV.FDILNSMCILENYNDLLLYLESNLM..sI--DHKKLVVPP....FDVFMILL..TVCTI.TPNYKNNIIQENDHYNTTL-.........-TLLNRRVQ..NILKMYIKIVKDFNTSKYEVYDLELLRCQLFLMVDSLi....pSKHTISTNNNK.RKNKNNSLE-----------EN--KLFFPNKYESYVYCLDKNIETLGNTLLHLVFHKYGEFT....N...CIL...WTLVNSM-----SNTNENFLTTI.......-EIWIPLLNIIFDILEL----.RHE..YFIMNELRK.ELPKS.IF-DEls....esPLAKLFKmFVVSHNFSTRFCEYI..FIECEGLKT...SNS.....LNYRPHPIYHG--ENTFNN....TYV....QRVNYSKRYKLEKSFIFRRRIISLCYKLVSDLPRSKKL..lSDPR.MNKSTLTDHIVDSLLKLQDIVEFKTFFksddllqdigylpylaqktffVIRDQVLYPET.HNQYPTFNRdt...........eecNFVENFGED-DKF............LE.ELLDLVEEs.........................edLFTNFNGQPF-EKA..FLLIEKSKICLVTLIK.YFLYLECND---------.........------tsdlnhilidsl................................
I2H401_TETBL/8-421                   .....................dsgdgsdmeiirdsqtddndddsliilndfkenpyeslldstddehdnnqfldeslagdaifslitqhkqstnldldkn------------------.......--.....------------.-------------------------...------------....--------..-----.------------GGNNIKNEpsikdskveIKQSDLGDD..FD-EELGKKMKRFRDISDDITTLKKRALDYEYRTDSN......NIALLKKQIKY.KEISNNYLEMVANETLSGKYKDWFFFTENSRFNEDI-LED-----IENFSSKEIMLKYGDFK....KllvCFG...TNIKYLY------QDYNISDLKY.......------KYDTLSILQPIDTMK.VIIghYFIIDPIN-.-----.-----........FKKFFPS.LLLDRNFYESLSIDDdwCTSFYNKIT...P--.....--KIFFKNYFKVVNKTDFF....LHY....RLIRIIPSSKNL---------------IISLIFSTSV-...-EVK.DVEKNPVIEMFNYLIDEKNYKNLLYFI.....................-----------.---------................--LVLSGSNLVPF...........gSN.KYVDYFQS............................CINDISDENS-NEV..ELTL------------.------------------.........------vrnilklfe...................................
G8JMX5_ERECY/8-403                   snsedeerlvqlqlsenddqdevinridsdlsdnisslsgdnynedpsqdvlndpilqsmgnksdplyiydsedeypfkykvrsneddpslpitrkdvdf------------------.......--.....------------.-------------------------...------------....--------..-----.--------------------.........---------..-NLLSNIEKIEEVHKDIETSPEKQISALSSIIK----......QREDMIKLSIK.NPISQQLLDFLVRD-KLETTKDWYFITDSPTYQEPS--------LLDKFSGKQKTY------....-...---...-GIEELYVQFGVCKAKLDPSFAI.......--TNYKNFDQMNNRVPVELMC.DEI..LRHVPTTNK.RDIAL.-----........SLRYFIL.FILDRKVFESDALTMswIVDTWIKHR...---.....-FSDHLDVYLSLVPKDCYF....LHH....RFTRLLP-IKSE---------------LIKKLFSDLT-...----.---PQAVAQKFDELMDQKNWFQMLYFI.....................-----------.---------................--LFINGITELPK...........gSN.GIWHYFRD............................CIYDMNIDNV-SSI..ELSVLK----------.------------------.........------syinlcin....................................
G0W780_NAUDC/330-471                 ...........................................................................................ennsdeiqm------------------.......--.....------------.-------------------------...------------....--------..-----.--------------------.........---------..-------------------------------------......-----------.--------------------------------------------------------------....-...---...-----------------------.......---------------------.---..---------.-----.-----........-------.---------------..---------...---.....NKGNFIKIYFEVVDRENYL....LHY....RLIRLIPELQKD---------------IINHLFENTVK...NGNG.GDDNIRIVEEFNNLFDNKQYHKLLYYI.....................-----------.---------................--LLIYGSDLMPF...........gHN.KTTEYFKD............................CIYDMTVEGN-NEV..ELSI---L--------.------------------.........------kgilnifykitdkivdv...........................
S6EHA9_ZYGB2/94-380                  ...........................................................................elrkpsilpggqddnrtrllsqlqn------------------.......--.....------------.-------------------------...------------....--------..-----.--------------------.........---------..-------------------------------------......-----------.KQVSPQYLDLIVKESISGRYIDWHFITENSEFQDVS----IEQELLADEKGKIVQEDIRALY....P...---...-SLKCFLNSIGVSDLTMRSLEAPs....pkPLTANRRYDSLCAISPVESMM.RAF..KTYSDCGT-.-----.F----........FLKSLIC.FILDRKIWESMECDAhwCHNILAEFT...T--.....--QQVLDEYLMLVERRDYF....MHY....RFVRSFPHLQLA---------------LIRQLINPLK-...----.---TQAIMEEFERLMEEKSYQPLLYFT.....................-----------.---------................--LLVYGSRLMPF...........gNS.STTLYLKE............................CTEDLCNEST-NAV..ELSL------------.------------------.........------lrgilg......................................
NSE5_YEAST/1-517                     ....................................................................................................MDGALINSVLYVSPRNGA.......-H.....YFVELTEKHLLA.FEMLNSMCLLENYDHVLLFLECQ--...-FGKSHNLAVIP....FDIILVLF..TLSTL.SEYYKEPILRANDPYNTSR-.........-ETLSRRAL..KLLQKYLAILKEFDSEQYNLYDLELLRCQFFLAIDTL......TPKKQKWGFDR.FRRTKSESGVTYRQNASVDPELDQAKTFKNPYRSYISCLEQRNTILGNRLLNLKLNEPGEFI....N...MIL...WTLSNSL------QESTPLFLSS.......HEIWMPLLEILIDLFSC----.RQD..YFIQHEVAQ.NVSKS.LFVQRls....esPLAVFFE.SLNTRNFANRFSEYV..FLNCDYKLP...SDN.....YATPVHPVYNG--ENTIVD....TYI....PTIKCSPLYKSQKSLALRRKLIGSCFKLLLRVPDGHRL...ITPR.IVADDVIQGISRTLASFNDILQFKKFFmtenls........qesyfipLLAEGTLSEIL.KDTQECVVI...............lTLVENLSDG-VSF............CN.EVIGLVKSk.........................cfAFTEQCSQASYEEA..VLNIEKCDVCLLVLLR.YLLHLIGTEAILDAKEQLe.......mLHAIE-k...........................................
J7RGY0_KAZNA/158-483                 ................................................................................................nskl------------------.......--.....------------.-------------------------...------------....--------..-----.--------------------.........---------..-------------------------------------......-----------.----------------------------QNPYKSYISLLTKKEHVLNNQLLHLKLSKRGEFV....N...MLR...WTLACSL------DERVTYFMSA.......HEIWDPIVNLLLDLLDL----.RQK..YFVLNEITL.SKKKKrTFVQRls....esPSVKFLK.IIDTFHFGPLFTEYL..FTGCNDDRT...---.....RNKTIKPVYND--ETQLSQ....AFV....PRFKYPKSYILEKSMKLRKRLLVACFNLLITVPRGHRL...CTIH.LETDDFLNNLSWELIGLKSIEYFQAFFktyd.............rereLAFMPVINEKI.INDITDLKFnl............vdQIVSIRNFL-KEW............TS.VIHSYLLL............................KLQELSK----AGV..VLEIYQIQTCLLALFE.YFEFIHEKD---------.........------gikkskfvcilrdi..............................
C5E4U6_ZYGRC/2-371                   ....................................................................ssdsdedaiifrqnvndneldsssssssstde------------------.......--.....------------.-------------------------...------------....DDRLLQTLkrTSYSS.RRVTRSSPIKK---SKSVQ-.........IQKFDLGR-..----NFDPQLASSLDRIQNVKDEVDNPSTVTTVKEQ-......KSNTVRSRIKP.RDASSQYIDLIVRETISGRYIDWHFISNDTRFEDVD----IDDELIEDSDNHAVRD----AI....R...RKY...PTLLELIESLGADLSLLQEDKPL......tRK---RDYDSLSEMTPVDSMM.RAI..GCYQDDKQ-.-----.-----........FIKYLLC.FILDRKIWESQDCDDdwCSQMLESVG...D--.....--EQIIDFYLSLVDPKDYF....MHY....RLSRCISRLQSP---------------LIHRIIR----...----.---PITIEEEFTQLIEDKNYESLLYFT.....................-----------.---------................--LFVYGSHEMPF...........gPS.SRTQYFKD............................CVEDMCNEGT-NAV..ELSL------------.------------------.........------lrgllslfl...................................
E7LTS1_YEASV/1-460                   ....................................................................................................MGSVNSSPNEEFETVPDSqi...sgFDsplipTSVGSYFRDDDD.DEKVHPNFTSDPENDSLNSDEEFSSlenSDLNLSGAKAESgddfDPILKRTI..ISK--.RKAPSNNEDEEIVKTPRKLVny.....vpLKIFNLGDS..FD-DTITTTVAKLQDLKKEILDSPRSNKSIVITSNTV.....aKSELQKSIKFS.GSIPEIYLDVVTKETISDKYKDWHFISXNCHYEQLMDLEMKDTAYSFLFGSSRSQGKVPEFV....H...LKC...PSITNLLVLFGVNQEKCNSLKIN......yEKKENSRYDNLCTIFPVNKML.KFL..MYFYSDDDN.DDVRE.F----........FLKAFIC.LILDRKVFNAMESDHrlCFKVLELFN...E--.....--AHFINSYFEIVDKNDFF....LHY....RLLQIFPHLQSA---------------LLRRRFSEKQG...RTET.I--QQNIIKEFNEFFDCKNYKNLLYFI.....................-----------.---------................--LTMYGSKFIPFg..........pKC.QVTEYFKD............................CILDISNETT-NDV..EISI------------.------------------.........------lkgilnlf....................................
K0K7N9_WICCF/16-114                  .........................................................................................qeellrtfinv------------------.......--.....------------.----------KQYDKLLFFLESTL-...-FNNAPTLNCPS....PFVINCLF..TLATL.GEYNNAGLIRKNFEKPLSQ-.........-QPVSVRAI..NILRRLVNIVKELDEDVKDEK----------------......-----------.--------------------------------------------------------------....-...---...-----------------------.......---------------------.---..---------.-----.-----........-------.---------------..---------...---.....-------------------....---....--------------------------------------...----.---------------------------.....................-----------.---------................-------------............--.--------............................--------------..----------------.------------------.........------sn..........................................
E7QDU7_YEASZ/1-460                   ....................................................................................................MGSVNSSPNEEFETVPDSqi...sgFDsplipTSVGSYFRDDDD.DEKVHPNFTSDPENDSLNSDEEFSSlenSDLNLSGAKAESgddfDPILKRTI..ISK--.RKAPSNNEDEEIVKTPRKLVny.....vpLKIFNLGDS..FD-DTITTTVAKLQDLKKEILDSPRSNKSIVITSNTV.....aKSELQKSIKFS.GSIPEIYLDVVTKETISDKYKDWHFISENCHYEQLMDLEMKDTAYSFLFGSSRSQGKVPEFV....H...LKC...PSITNLLVLFGVNQEKCNSLKIN......yEKKENSRYDNLCTIFPVNKML.KFL..MYFYSDDDN.DDVRE.F----........FLKAFIC.LILDRKVFNAMESDHrlCFKVLELFN...E--.....--AHFINSYFEIVDKNDFF....LHY....RLLQIFPHLQSA---------------LLRRRFSEKQG...RTET.I--QQNIIKEFNEFFDCKNYKNLLYFI.....................-----------.---------................--LTMYGSKFIPFg..........pKC.QVTEYFKD............................CILDISNETT-NDV..EISI------------.------------------.........------lkgilnlf....................................
E7LYN6_YEASV/1-517                   ....................................................................................................MDGALINSVLYVSPRNGA.......-H.....YFVELTEKHLLA.FEMLNSMCLLENYDHVLLFLECQ--...-FGKSHNLAVIP....FDIILVLF..TLSTL.SEYYKEPILRANDPYNTSR-.........-ETLSRRAL..KLLQKYLAILKEFDSEQYNLYDLELLRCQFFLAIDTL......TPKKQKWSFDR.FRRTKSEKGVTYRQNASVDPELDQAKTFKNPYRSYISCLEQRNTILGNRLLNLKLNEPGEFI....N...MIL...WTLSNSL------QESTPLFLSS.......HEIWMPLLEILIDLFSC----.RQD..YFIQHEVAQ.NVSKS.LFVQRls....esPLAVFFE.SLNTRNFANRFSEYV..FLNCDYKLP...SDN.....YATPVHPVYNG--ENTIVD....TYI....PTIKCSPLYKSQKSLALRRKLIGSCFKLLLRVPDGHRL...ITPR.IVADDVIQGISRTLASFNDILQFKKFFmtenls........qesyfipLLAEGTLSEIL.KDTQECVVI...............lTLVENLSDG-VSF............CN.EVIGLVKSk.........................cfAFTEQCSQTSYEEA..VLNIEKCDVCLLVLLR.YLLHLIGTEAILDAKEQLe.......mLHAIE-k...........................................
J7RGY0_KAZNA/1-161                   ..................................................................................................md---SCHSSVRYVSGGKDDl.....lKH.....YHVELTEKCLRT.FEILNSFSLLDNYDGVLLFLEYQIY..nANCQLDIPVVP-....FDVILVLF..TLVTI.SEHYKEPQLRDNDPYNVCR-.........-QPLNRRAV..KILRFYVNLLKEFDVEAHGRYNLELLRCQFFFALDCL......-----------.--------------------------------------------------------------....-...---...-----------------------.......---------------------.---..---------.-----.-----........-------.---------------..---------...---.....-------------------....---....--------------------------------------...----.---------------------------.....................-----------.---------................-------------............--.--------............................--------------..----------------.------------------.........------iphghhprnwnskl..............................
G0W7I9_NAUDC/1-530                   ............................................................................................mrpscsrs--------VDYVIGNKSNer...rlPH.....YFVELTERHLGV.FEVLNSMCLLDNYDHILFFLECQM-...--VNTKTLPIPP....YDICLVLL..TLATT.SNYYKADILQASDAYNFTR-.........-QSLDQRAL..KILRFYIRILLEFDTSKYEQYDLEFLRCQFFLVIDTLs....pKRAYRNIDRFK.RRKVENSKL-IYGESISI--NEDELKDLQNPYRSYLSSLERKKSVLGNTLINWKLTQPGEFI....N...MIL...WTLSNSL------QDDPALYLSS.......HDVWMPILDIILELFNL----.RQK..YFLKNEIGK.GISAD.LCVQRls....esPLSRFFQ.SVDSIHFTSRFCDYM..FINCDYSLK..gSDN.....SSTSIHPVYHG--ENQLSK....LYV....PRTKYTKVYKARKSFQLRRKIIGSCFKLLIHVPDKHKL...ISPRgMSSNDIVDGISRTLATFQNIEQFRSFFlsdsls........qevffipLLAEGTLAEII.ENHRQHQEEgpk..........tsiKVVKYLGDT-EQF............LL.EFISLFEK...........................gFMVPYCDKKITEKV..ILEIKKGDICVLVLFR.YLLHLI------------.........------pskklkcvksfnhfievlkwndsk....................
J4U292_SACK1/1-507                   ....................................................................................................MDDALINSVSYVSPRESA.......-H.....YFVELTERHLLA.FEMLNSMCLLENYDHVLLFLECQL-...--DKSRNLAVIP....FDIMLVLF..TLSTS.SEYCKEPMLRANDPYNVSR-.........-ETLSRRAL..KILQKYLAILKDFDAEQYNLHDLELLRCQFFLAIDTL......TPRKQKWSFDR.FRRTKSENDVAYRPNASADPELEPSNTIKNPYRSYISCLEQTHTILGSRLLNLKLSEPGEFI....N...MIL...WTLCNSL------QESVPLYLSS.......HEIWMPLLEIIIDLFNF----.RQD..YFIHHEIAR.NISKS.LFIQRls....esPLATFFE.SLNTRNFANRFSEYV..FINCNYRAP...SEN.....YATPVHPVYNG--ENTIVE....TYI....HRFKYSALYKSQKSLALRRKLIGSCFKLLLRVPDGRRL...ITPR.IIADDVIQGISRTLASFNDILQFKKFFmtenls........qesyfipLLAEGTLSEIF.KDTQECVVI...............lTLVESLSDG-VSF............CS.EVIDLVRLk.........................cfTFTEQSKRISYEES..ILITEKCDVCLLVLLR.YLLH--------------.........------lvdvetitgtte................................
G8BZ47_TETPH/6-558                   .............................................................................................dtscesv---------EYTNN-GEDp....elPH.....YLVRLSDDVLRN.FEVLNSMYLLDDYDGLLMYMETQ--...--IDEKSFAVPP....YDIVIVLL..TLCTV.SNHYKDEMVRANDLYNITR-.........-QQLSKRAI..QLLRKFVQILRDFDLEKYNRYTLELLRCQFFLAIDSFni.rraQYSFDRVRRIR.TPNAIVYTE--LSAEEIDSANEKYIATIEDPYKAYHSSLKQKFSVFDNNLINLRLSEKGEFI....N...MII...WTLSNSV------QKEENLFISS.......HDIWLPLLGILMNIFDL----.RHC..YYVDRQINE.NVDAS.LKVQLlg....tsPLALFLK.SLDSMQLSQRLSEYI..FINLSYERD...-DS.....YNTYVHPVYYE--ENTFSK....QYI....SRINYSENYKYIISMAMRRKLIGLCFKLLLNVPKGHKL...VSPR.LVPDDFMKSIVKKLCLFDNINQFKAFFyivdls........helffipLLAEMTIGELY.HDMNPSKIK................DQLQIVDYL-DNF............NK.FLEYSIKLidqgfftmp..........idnssnnvsSDSDSNDENSDDKIkyVSPLQKIDICFSVVLR.YAVHLNDDGLEKSNI---.........------alfeqfiravnsvdqrrkkdasckislye...............
G0VJA4_NAUCC/1-511                   ....................................................................................................MSCSKSISYVLGDKKSND......lPH.....YFVELTESHLAV.FEMLNSMCLLDDYDHLLFYLECQI-...--NETKILTIPP....FDICLILM..TLVTI.SGHYKEQFLRTSDTYNFTR-.........-ETMNNRAI..KILRFYLKVLRDFDTDKYQQYDLELLRCQFFLAIDTL......IPKTLR-KKFF.RSKRMKVDTSRVLYVEKLEDDTISLGTIENPYRSYISCLEQKKTVIGNTLLTLKLSEPGEFI....N...MIL...WTLLTSL------QDDTALYTSC.......HDVWIPLLDILIDLFDL----.KHK..YFLRNEIVR.GISAT.LFVQRlt....esPLALFFR.SFGTTQFTARFCEYV..FVNCSYNLE..yDDD.....FKTEIHPVYRG--ENRLSN....LYI....PRMRYTKMYKIRKSLSLRRNIVGACLKLLVTVPNKHIL...TSPR.IASDTLIDQICVTLAKFSDVDQFKSFFftdsls........qelyfipLLAEGTLAELF.YNSGKLVKNlde.........kqplRFMENLSNV-DNY............LL.YCADLFEKg..........................fFMTESNQHIT-NVT..LTEMRKTDVCLLVLLR.YLLQFEMNH---------.........------aiisl.......................................
A7TR81_VANPO/1-415                   ....................................................................................................MSDNSSSIHDSQDSDESV.......--.....TTIYNSNNHKIK.DEKSTSKYPEVSDEEIDSDIDLYLIddsED----------....DEILLKMS..SFNGS.SKKPAVIKNEN--------Gy......inIKSFDLGDL..YN-EKVTKNLNSIESAEDKINNEKKKFVSKTFTKSN-......ELMAKLSKNFT.NSQLSYYIDTIIKDANPDKYLDWHFIEEDTTIDDISPILSFETAYYNCHDFNRIRHEILKSY....P...---...-NLNYILPTFGISKEKLNSINDGy.....fCISDYYNYDNLCTILPTDSMK.SII..IYYIDEPN-.-----.-----........FVKFFLC.FILDKKIYESNDCDSkwCEEIVSALD...---.....--VDVIEEYLKLINLDDYY....MHY....RLTKLLPSFKNK---------------LVDGIFGDNTL...A---.---LNRIIDEFNTIFDDKEYRKLLYFS.....................-----------.---------................--IFIFGSDLVPYs..........kESlPVIDYIFN............................CIRDVSDMTNVADI..ELLL------------.------------------.........------lksiltsftk..................................
Q6CWU9_KLULA/1-497                   ....................................................................................................MASQSH-KYDLGRNELNK.......PD.....YYVELTEKHLSD.FEIWNSLCSNESYDMLLYLCEQY--...--LNMGRFPVIP....SEVIAVLF..TLASI.GDHNKGSLIKKADPFDTGR-.........-ELLTRRSM..KLLETLLDILQTFDTDLYEIYDLELLRCQFFYFIDSIrpengrALVLDPLNAQS.SRATRRSFKLSSRSA-----EGGSLLSVEPLYGSYINLIGDDTSVFKTTMVHSALSQEGSFW....N...GFS...WALSTFMIGHENEDQKTDWDYEL.......AKAWLSVFKLIFIIYEL----.RQD..YYIDSKTET.IEKS-.-----........PIFRLLE.AVDKKNQLKGLVQYL..FVGCVECE-...---.....---ILYPVSPSLNDPSTSN....ASF....NQFHEDKDYRAAFSMDVRKDTLCVFVRFLDRYER--HL...QSYP.FTLDALYGTIVDALYSDLKISSFKQFFlscdve........kdrnlitTLVEKLLNKAF.SNVEPRRTFn.............ivNKMSNFEEV----............TS.ELMKLLRA............................--IDRSAAFNRSRI..SKRRIQMDFCIIILTR.-LIITTHPQGNFEELLRV.........LTTFAK............................................
G0VH93_NAUCC/88-432                  ......................................................................................ifkddnishkevei------------------.......--.....------------.-------------------------...------------....--------..-----.--------------------.........-KQFDLGRS..FD-KKLATNISKLDELIKLAEKSPLKSPVVNLDIDKA......KNAYRAQLKYK.GNINEHIVDMVVRETISGQFKDWHFIDSEYNFKLLDPILDSDDFFYL----NEIQM--TEKI....K...KQF...PTLHELCLALGCNKVKLNNIHIS.......-KEDLLQYDNLVELTPTENVM.KLI..CYYGSDPL-.-----.-----........FNKIFIC.LILDRKIYESLFCDSliCTTIYCKLIlqnDPD.....NESLFLQDYLQVVDKGNYF....LHY....RLIRLLPNLKNA---------------LIERLFKENQ-...-DTK.L---AQFVKTFNKLFDEKMYRDLLYFV.....................-----------.---------................--LFIYGSDEMPF...........gNS.KTTEYFKD............................CVYDMTQDGT-NDV..ELSL---MKGVLNLF-.------------------.........------yqine.......................................
#=GC seq_cons                        ......................................................................................................................................l....p......p..p........t..h...-.........................lh.hhh..h.....tth.pt...pt......t............t.hshts...h..pphhphlpphpstt.th.p..hhpsphhhh.sp.......p.ph.h...hp.tphsp..hshhhptt..sp.ps..hhs.ps.apphh.....t.thht....phhhtp.sphh....p...hhh....oLps.l......ppp.s.hh.........tp....hh-.lhplhsl.....+....hhh.pchs.....t................lthFhp..l.spphhpthpp.h..hhph..th..............t.hhssYht..-ts.......hah.....hh+h.s.hp.................lLtpl.pttph...........pphl.p..ppLhs.pphpphhhFh............................................................l..hust..sh.............p.phhphhcp............................thh-.stp.s.pph...lpl..............................................hhh.........................................
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