GenomeNet

Database: Pfam
Entry: Nse5
LinkDB: Nse5
Original site: Nse5 
#=GF ID   Nse5
#=GF AC   PF08691.7
#=GF DE   DNA repair proteins Nse5 and Nse6
#=GF AU   Mistry J, Wood V
#=GF SE   manual
#=GF GA   25.00 25.00;
#=GF TC   44.10 28.50;
#=GF NC   24.40 21.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   16478984
#=GF RT   The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6
#=GF RT   complex. 
#=GF RA   Pebernard S, Wohlschlegel J, McDonald WH, Yates JR 3rd, Boddy
#=GF RA   MN; 
#=GF RL   Mol Cell Biol. 2006;26:1617-1630.
#=GF DR   INTERPRO; IPR014803;
#=GF CC   Nse5 and Nse6 are non essential nuclear proteins that are
#=GF CC   critical for chromosome segregation in fission yeast [1].  Nse5
#=GF CC   forms a dimer with Nse6 and facilitates DNA repair as part of
#=GF CC   the Smc5-Smc6 holocomplex.
#=GF SQ   50
#=GS J7RGY0_KAZNA/1-160    AC J7RGY0.1
#=GS J8LPK5_SACAR/32-468   AC J8LPK5.1
#=GS C5DLK2_LACTC/150-411  AC C5DLK2.1
#=GS H2AT47_KAZAF/153-497  AC H2AT47.1
#=GS Q756F5_ASHGO/1-501    AC Q756F5.2
#=GS Q6FSX3_CANGA/1-531    AC Q6FSX3.1
#=GS C5DLY3_LACTC/1-507    AC C5DLY3.1
#=GS B6JV13_SCHJY/1-562    AC B6JV13.1
#=GS J7S707_KAZNA/82-379   AC J7S707.1
#=GS NSE5_SCHPO/1-387      AC O94668.1
#=GS A7TR81_VANPO/1-417    AC A7TR81.1
#=GS E7LTS1_YEASV/1-461    AC E7LTS1.1
#=GS KRE29_YEAST/1-461     AC P40026.1
#=GS G8ZMA9_TORDC/4-508    AC G8ZMA9.1
#=GS C5DWA7_ZYGRC/1-507    AC C5DWA7.1
#=GS G8JT19_ERECY/1-519    AC G8JT19.1
#=GS Q753U0_ASHGO/1-413    AC Q753U0.1
#=GS G0VH93_NAUCC/89-432   AC G0VH93.1
#=GS E7KSD9_YEASL/1-517    AC E7KSD9.1
#=GS Q6CYC9_KLULA/1-375    AC Q6CYC9.1
#=GS A7TFV6_VANPO/1-559    AC A7TFV6.1
#=GS E7KBP7_YEASA/1-360    AC E7KBP7.1
#=GS G0W7I9_NAUDC/1-538    AC G0W7I9.1
#=GS H2AT47_KAZAF/1-162    AC H2AT47.1
#=GS B5DT85_DROPS/110-253  AC B5DT85.1
#=GS S6E807_ZYGB2/1-511    AC S6E807.1
#=GS S6EHA9_ZYGB2/95-381   AC S6EHA9.1
#=GS K0K7N9_WICCF/17-114   AC K0K7N9.1
#=GS NSE6_SCHPO/1-478      AC O13688.1
#=GS E7NLB7_YEASO/1-325    AC E7NLB7.1
#=GS J7RGY0_KAZNA/159-485  AC J7RGY0.1
#=GS I2H2P8_TETBL/1-516    AC I2H2P8.1
#=GS G8JMX5_ERECY/8-403    AC G8JMX5.1
#=GS NSE5_YEAST/1-517      AC Q03718.1
#=GS C5E4U6_ZYGRC/2-371    AC C5E4U6.1
#=GS S9VVH5_SCHCR/172-477  AC S9VVH5.1
#=GS G0W780_NAUDC/330-473  AC G0W780.1
#=GS G8BZ47_TETPH/5-541    AC G8BZ47.1
#=GS E7LYN6_YEASV/1-517    AC E7LYN6.1
#=GS G0W780_NAUDC/3-309    AC G0W780.1
#=GS K0K7N9_WICCF/216-303  AC K0K7N9.1
#=GS E7KML7_YEASL/1-461    AC E7KML7.1
#=GS G8ZU95_TORDC/80-398   AC G8ZU95.1
#=GS G0VJA4_NAUCC/1-511    AC G0VJA4.1
#=GS Q6FWW8_CANGA/1-360    AC Q6FWW8.1
#=GS J4U292_SACK1/1-514    AC J4U292.1
#=GS Q6CWU9_KLULA/1-497    AC Q6CWU9.1
#=GS E7QDU7_YEASZ/1-461    AC E7QDU7.1
#=GS I2H401_TETBL/8-423    AC I2H401.1
#=GS G8BTX3_TETPH/2-431    AC G8BTX3.1
J7RGY0_KAZNA/1-160               .................................................................................................md---SCHSSVRYVSGGKDDl.....lKH.....YHVELTEKCLRT.FEILNSFSLLDNYDGVLLFLEYQIyn.anC-QL-DIPVVP....FDVILVLFTLVTI.SEHYKEPQ..LRDNDPYNVCR...........QPLNRRAV..KILRFYVNLLKEFDVEAHGRYNLELLRCQFFFALDCL......-----------.----------------------------------------------.----------------....-...---...--------------------.---.......-------------------...------------.-----.-----........-------.---------------..--------...-.---.....-----------------..-....------------------------------------------...----.---------------------------.....................-----------.---------................-------------............--.--------............................--------------..----------------..-----------------..............------iphghhprnwnsk..........................
J8LPK5_SACAR/32-468              ........................................................................................agsifrddddv--------VDDDDDDDDK......vRP.....NFISNTEDDSLDsDEDLS----DLDGDLTLPSAEPNSi..ddF----------....DPILKRSILSK--.RRAPSNDVdgDEEISRTPKKLinf.....vplKNFNLGQS..FD-TTITTKVTKLRNLNKEILDSPRESTNVV-VTSTIt....aKSELQRNIKFV.GNIPEVYLDLVTKETISDKYKDWYFISENCHYEELMDLEMKDMDYS.FLYSNSACQDDVPDFI....R...SSF...PSIANLLASFGVNQEKAKLL.KID......yGKNENSKYDSLCTIFPVEKm.lKFLMYYYSDDKE.--ERE.I----........FLRTFIC.LVLDRNVFNAMEMEYkiCSKVLELF...N.E--.....--EYFINLYLEIVRKDD..F....FLHYRLLQIFPNLQIL---------------LLGRLFDEKEA...RSKT.I--RQSLINKFNELFDYKNYKNLLYFI.....................-----------.---------................--LTIYGSKLIPFg..........pES.QVTEYFKD............................CILDVSNETT-NDV..EISI------------..-----------------..............------lkgilnlfs..............................
C5DLK2_LACTC/150-411             ........................................................................................aasasdkkppl------------------.......--.....------------.------------------------.....-----------....-------------.--------..-----------...........--------..-------------------------------------......--RKQVASSFK.QKVPRAYLDMILAENSSRKFQDWYFMTENAQPAEID--------PW.ATFLGAKKPKKQ----....-...---...-SLKELLKSLGVPSQHLSPQ.--L.......QHITVDMYDTVNLLQPVHVm.cKQLQRYY-----.-----.----Kc.....rgFAQSFIC.FILDRNVFNSPECTSawCEDVYSRL...D.A--.....--NHFTDTYLQLVAGDS..Y....LLHLRVSRQIPEFHEL---------------LLEKLFPQHT-...----.---YETLLGEFDRLLKAKEHQKLLYFT.....................LFIYGTAT---.---------................-------------............--.--------............................--------------..----------------..-----------------..............------mpfgdtaasqrlrdsvygagndgnhvelviir.......
H2AT47_KAZAF/153-497             ............................................................................................ksfnqle------------------.......--.....------------.------------------------.....-----------....-------------.--------..-----------...........--------..-------------------------------------......-----------.--------------------------SITNPYTAYFTLLKQKETIL.GNRLLNVQLAKPSEFL....N...LIL...LTLSYSL------EETEGKY.LSF.......HERWGPMMDILTDLISL--...RHKYYMKNEIAKeKIKSS.LYTQRls....esPLACFFK.LFNTFAFKDRFTEYI..FIGCNIKG...I.AADrsnkySSFNPHTIFKG--EDAI..S....TTYVARTAFSTAYKVKKSMRLRRRIINKCFKLLSQVPKRHRL...VSPR.MDIDDIITNISITLSNFSNLMEFFAFFdtesps........kdfsflpVVAENTLNELL.FRLESNEGAkeefylsrgqgnditvNLVSNLSNT-DAF............LK.ECLMLLEE............................-KLSTNDS---LKT..PLLIQKSLICILSLLR.fLMFLN------------..............------dkeamr.................................
Q756F5_ASHGO/1-501               ...................................................................................................MNASVGDHDMPSPSEAAV.......PH.....YFVELNEHYLKD.FEQFSSLCSLDEYEQLLYLLEEK-.....-FVAGRVAIPP....GDVIVVLLTLATA.SSHYKADF..VRANDPYNVGR...........TDIAHRSM..RLLSRLVDAVEEFDDRRYMRFELELLRCQLFLFLDSIv...pkRPEVTIAKRVR.THGKNQPTDIPFAPDEMPLCVD----SLRSASYKYVSVLETKKAVF.QNVLLTHVLSQNGGFW....N...CVA...WTLSTMI-------DKDAVK.NYC.......GETWFPIVTFLFRLYEL--...RHAYYMQYEMTQ.GISSA.AYTKEla....dsPLVLLFK.SLGSNNVHITLCDYL..FVNCGKNV...-.---.....GRGEARPVYHS--ELKL..S....ATYVPFCKPSTEWKLFKSMQLRRRILSCYFKVLADIPKDHRI...K--P.FSEDQSIKYMVRTLLELETVEMFQAFFftddlk........itmhylpLLAEHIIVVLL.EDCGKAIES................TLVTNLGNL-DVV............IE.NIEEYLEM............................RPVDCSNAIGLHKT..VFYI---DTCTLVLIK.yAILLHGTDVLLTGGLDM.............vLKRFFK.......................................
Q6FSX3_CANGA/1-531               ...................................................................................................MSGVSVSVEHVVGNQIGKg.....lPH.....YFVELGDKDITS.FETQNSLYRAEDYDHLLFCLEERWq..dgDSAFDPLFVPS....FDIIIVLFTLITV.SDHYKATV..LTRNEPYNVNR...........VSYSKRAI..KILRKYLRILQQFDTTRYGTYKLELLRCQMFLAIETV......NPHFKYLQNCR.SVKNSTNENVYYKPDAMP--ENIIRRGIVNPYRSFISCVETKNPIF.GNIPVNFKLSQRGGLS....N...AIL...WTLANSI------QEDDLLF.HDA.......YEIWIPLFDIFISILEI--...RQAYFLENEIVK.KISKE.LRIQKlm....esPICQFLS.FVDSINFNPLFCEYV..FVNCDYTL...I.NRD.....AALTIQPVYKG--ETQP..T....EVYYQRVKYTKQFKAKVSMRIRRRFISLCFNILGSVPTGLHL...PKPR.IHKKRLLVEMSRTLSTFQNIVEFEEFFtfdy............eefmfHLIERTLYELF.KQDRRTIVTe.............rpSLISGKDDL-KTF............FN.EILALFKAgaftpdv.............ringlpphEIIDNAGHVKNEK-..-LRLQKIDVCICTILR.nVLQGQAKPLLVDCKKLL..............IK----vskrini................................
C5DLY3_LACTC/1-507               ...................................................................................................MSILSHGSEKVGVP----.......--.....YNVGLTTESLSV.FEVLNSLCVVENYDQLLYYLEAR-.....---RSALAVPP....ADVLIVMMTLSVI.PDFGAATL..EAEMDPYNVGR...........ASLATRSI..KLLRHFTDILLSEHAEEENHYSLALLRSQFFIMLDQLslrgitSTRVRERDFTK.RRKTNSGVLLEASPSIFRDDQSPPLLSFKNPYPSYVSCLEHRPEVL.KNMPITSKLSQEGEFW....N...CVG...WALYASL-------SDDSHI.YER.......SKVWFAVLSVLFDAFEM--...RNKYSIDSETDP.TANNA.ARLSFie....rsPLVALFR.SLNSQGLIQAFCDIL..FLGCSYEL...-.--A.....GKLRVHCVYPK--ELMQ..V....DTYVPKLLARTSCKFTQSMSFRHRLLSLFLTMLRSIPEGVEF...SKPC.LSEAGFVRHLGKVLSSFEDTSQLKQFFsvtnpy........efldympLFAQAAANESL.KAFDANYTL................SLVEKLANN-DLV............IE.ELGNVFEAg..........................fPPLDENYDSRPEQF..YSSIEKCDIFLLVILR.yWEYIHGAQLKMTRMRCA..............IRAL--sv.....................................
B6JV13_SCHJY/1-562               ...................................................................................................MASQHFSDAEIPDSQSSSgs...stPS.....SPTSSPSSASST.SEALPAVSALLPTASRVRTRSARLrakrrCLPTRSYVWS-....LDRLSKSAVKDAT.LSHRRKNV..IQKLTHYGSAQsqg.....trvASVEKAIL..KNLGMNESVLSSIKAEQDTQDAASEFHYSYVGVVATG......EKSLWSSPKEE.GRESSPVDVSSLSPSDVADFVCSGLLSFEDVVSQIF----------.-----TRFFENKGANC....E...EWA...VCLQRCLDKLSSSSTKPILL.PYI.......SS----VLQAVVDMLGIDVg.kRHTPVAHDSVRP.PASTA.PSNYSva...atvKLLTLLY.PLCELPLQKDIVADL..CRIALDTA...V.SDD.....VRLVIMDAFASILKVPR..A....THSRTRSRSSDDAWQILYETTTNAQAWVTLLMLLPNRKGIIR...NRQK.LALSWFLSKPLQSINNNNDNASLFAEV.....................CEAIEALPNKT.AEDFVRVRYs.............isALFFAFHGELAPQ............PD.EVLRLLAL...........................lRKLDHSIHGTTTDS..LMLLRCEAKDVVQRLYlyVYYEHCNAYQVLEQAADmnmnvsaadlqddiI-----aptakseavtagdikvavkdnleaeteeepksevkaeak
J7S707_KAZNA/82-379              ...................................................dgqfdrlrqveeelhfsqelelhptptllrdklsqqrdnlkqrvkapl------------------.......--.....------------.------------------------.....-----------....-------------.--------..-----------...........--------..-------------------------------------......-----------.--VTEYTLDLISKETVSDKYKDWFLFTEGPMDGNNA-------AIS.D----------T----....-...---...-SLTQLLIQFGATPSSLQSD.FIL.......KDEDLEHFDTFCDIYPVDYmmeRIRPLILSHEDV.GV---.-----........ATRLFTF.FILDRNVYSSKECTQewCTQVFESL...L.SRT.....TVEEFIAQYFAQLQLHDrfY....FLLERLTKLIPPVRIH---------------ILNQLFPK---...----.---TTAVINTFNELFDAQNYKDLLYFV.....................-----------.---------................--LIIFGSDNCNF...........gES.TVAQYFKD............................CILDACEDGA-NGV..ELTI------------..-----------------..............------ivgiinvfvk.............................
NSE5_SCHPO/1-387                 .............................................................................................mnsalk------------------.......--.....AIIELCIEEDLL.PKSLDVLEYLLSTTSIPIP-----.....-----------....ACYIRMCITLLVH.PEYPTSSN..IQE-------Scnw.....ilqQVVENRSK..INFDAWSFENDLSDNDMPKENYLKIFSNQCLFTQDVDy...wdLIAYMSSRPPD.LERWMSLMDIWLRILEIDAEENGSALMKKYMGEDLCELQDAIRICF.SCFTLPQQTMES----....-...---...-PFATSMSKAPAKTESRGSN.---.......------SFEGTSRLANLGA...------------.-----.-----........KLLCLIW.AMLPKGRF--FVVHLtdAFHFLSKL...D.ERF.....SKLNAKQQDLFFGNLGA..S....NLRYCLSQYI---------------------LMKGIGIGINI...RHTR.CEFTKQLTQLLPTSLPKNKIRQKLHLR.....................-----------.---------................AWVSFLGSALRES............DR.NFDKELFY............................TTLKQLYTMYQQTE..LVGIDRPMAI----LK..-----------------..............------dmlvlldiskklsldki......................
A7TR81_VANPO/1-417               ...................................................................................................MSDNSSSIHDSQDSDESV.......--.....TTIYNSNNHKIK.DEKSTSKYPEVSDEEIDSDIDLYLiddseD----------....DEILLKMSSFNGS.SKKPAVIK..NEN-------Gyi.......niKSFDLGDL..YN-EKVTKNLNSIESAEDKINNEKKKFVSKTFTKSN-......ELMAKLSKNFT.NSQLSYYIDTIIKDANPDKYLDWHFIEEDTTIDDISPILSFETAYY.NCHDFNRIRHEILKSY....P...---...-NLNYILPTFGISKEKLNSI.NDGy.....fCISDYYNYDNLCTILPTDSm.kSIIIYYIDEPN-.-----.-----........FVKFFLC.FILDKKIYESNDCDSkwCEEIVSAL...D.---.....--VDVIEEYLKLINLDD..Y....YMHYRLTKLLPSFKNK---------------LVDGIFGDNTL...A---.---LNRIIDEFNTIFDDKEYRKLLYFS.....................-----------.---------................--IFIFGSDLVPYs..........kESlPVIDYIFN............................CIRDVSDMTNVADI..ELLL------------..-----------------..............------lksiltsftkii...........................
E7LTS1_YEASV/1-461               ...................................................................................................MGSVNSSPNEEFETVPDSqi...sgFDsplipTSVGSYFRDDDD.DEKVHPNFTSDPENDSLNSDEEFSslensDLNLSGAKAESgddfDPILKRTIISK--.RKAPSNNE..DEEIVKTPRKLvny.....vplKIFNLGDS..FD-DTITTTVAKLQDLKKEILDSPRSNKSIVITSNTV.....aKSELQKSIKFS.GSIPEIYLDVVTKETISDKYKDWHFISXNCHYEQLMDLEMKDTAYS.FLFGSSRSQGKVPEFV....H...LKC...PSITNLLVLFGVNQEKCNSL.KIN......yEKKENSRYDNLCTIFPVNKm.lKFLMYFYSDDDN.DDVRE.F----........FLKAFIC.LILDRKVFNAMESDHrlCFKVLELF...N.E--.....--AHFINSYFEIVDKND..F....FLHYRLLQIFPHLQSA---------------LLRRRFSEKQG...RTET.I--QQNIIKEFNEFFDCKNYKNLLYFI.....................-----------.---------................--LTMYGSKFIPFg..........pKC.QVTEYFKD............................CILDISNETT-NDV..EISI------------..-----------------..............------lkgilnlfs..............................
KRE29_YEAST/1-461                ...................................................................................................MGSVNSSPNEEFETVPDSqi...sgFDsplipTSVGSYFRDDDD.DEKVHPNFISDPENDSLNSDEEFSslensDLNLSGAKAESgddfDPILKRTIISK--.RKAPSNNE..DEEIVKTPRKLvny.....vplKIFNLGDS..FD-DTITTTVAKLQDLKKEILDSPRSNKSIVITSNTV.....aKSELQKSIKFS.GSIPEIYLDVVTKETISDKYKDWHFISKNCHYEQLMDLEMKDTAYS.FLFGSSRSQGKVPEFV....H...LKC...PSITNLLVLFGVNQEKCNSL.KIN......yEKKENSRYDNLCTIFPVNKm.lKFLMYFYSDDDN.DDVRE.F----........FLKAFIC.LILDRKVFNAMESDHrlCFKVLELF...N.E--.....--AHFINSYFEIVDKND..F....FLHYRLLQIFPHLQSA---------------LLRRRFSEKQG...RTET.I--QQNIIKEFNEFFDCKNYKNLLYFI.....................-----------.---------................--LTMYGSKFIPFg..........pKC.QVTEYFKD............................CILDISNETT-NDV..EISI------------..-----------------..............------lkgilnlfs..............................
G8ZMA9_TORDC/4-508               ..............................................................................................gianh--------TSIGENDDER.......LP.....YYVDVSDDTLFT.FEVLNSMCMLDNYDHLLFTLECQS....vD--EEKFAIPP....FDVLLVLMTLTTV.SDHYKEPI..LRQNDPYNTSR...........GKLSRRAF..KILRFYVKMLQKYDLNGGQRPDIELLRCQFFLIIDSL......SSNARWARPHR.RKRRKTENGVIYNF-DVAEAEDSELGNIIANPYPYVSCLEQKKSIL.GNDLLSIKLKQPGSFI....N...MIL...WTLSNSL------QEDNVLY.IDN.......HEVWMPLLELIVDLFVL--...RHDFFIKHELKS.AIDDY.HMVQLls....esPLANFLH.LIDSSQSGISFCQCI..FLSCDYKF...D.DLD.....VSIELHPVYYG--ENTL..S....KTYIPRTSFSKVYKLKRSMSLRRKIIGTYCKLLTEVPTGHQL...IKPK.PSADELIKNLSYSLAKFNDIDEFEAFFltgdlt........vasyfvpLIAEDTLCHLF.SNFKKSIERldik........hvalTLVENLDNI-GAF............LY.ECTCFFDK...........................gFFVPPERQIK-SIE..LVEINKADICMLALFQ..YI---------------..............------kfleggeviks............................
C5DWA7_ZYGRC/1-507               ...................................................................................................MGCECSAEFVKGKNGEGF.......EH.....YHVELTESMLNG.FEVLNSMCLLNNFDHLMFFLECQM.....GPSSCELVVPP....FDVFIVLMTLVTV.SDHYKDES..LRANDPYNVSR...........LSLSQRSL..KVLQFYVKKLNEFDVEKYGRYQLELLRCQLFIAYDSIs...pgSDKFYRKKKLR.RTGSGRLFD-----------NDFPTVEFKEPYKSYISCLDQKQEVL.GNTLLNLKLNQPGEFK....N...MIL...WTLSNSM------QSQQVLY.LAS.......HNVWMPLLDLLLDILTL--...RYDYFVKNEAER.DDDNK.-YVQQls....scPLALFLR.VFESIQFSSVFCECV..FSNCDYEL...D.DTL.....TALKIHPVYHG--ETTL..S....NTFHPRVKYTDSYKIRKSLALRRKLLGVCFELLTEVPNGHRL...IYPR.MIPEDISSRIAVILVNFKNLEQFKAFFsnnmdk........rpsyvlaYIVDDTLLEMF.KKFGRKPLKk.............seIGILADSHDVDTL............FK.NCKYYIES............................GLFAPWDSKNPEKS..YLDIQKADTCLIVSMK..CYAKNGDAVNISNKKEF..............LKALL-e......................................
G8JT19_ERECY/1-519               ...................................................................................................MAASSH-HYVVGSNDAGL.......PH.....YFVELNEQCLKE.FEQYNSLCSVDEYEQLLYLLENK-.....-FLSGQVPIPP....SDVIVVLLTLATA.SSHYKDHL..IRGNDPYNVGR...........TDIAHRCM..RFLNELLRTVHVFELHKYELFELELLRCQLFTFLDSId...pkQSTSTISKRVR.TRTNNQVSDIPFIAEELPQSLG----SPETVNYKYISALETKKAVF.HNPLITRVLSQSGSFW....N...SVA...WALSSSV-------DDDPVK.HYC.......GEVWLPIIMFIFELYEL--...RHEYYKLHELGG.TDRLG.FTQKFi.....rsPLVSLFK.SLSSSNIHIALCDHL..FVNCGKGV...G.S--.....--GIARPVYHS--ELNL..S....ATYLPICKPSTSFKWYKSMKLRRRILGAYYRVLADIPSSQRI...K--S.FSEDQSIKYMSRILLQIDKLSMFESFFltdeis........atmhylpLLAEHTVVQLW.EDCNKTIEP................TLVDNLKNL-DAL............ID.NFEDLLEG............................EPKVCVNDLGLLKT..TGYI---YTCTLVLLK.cALFLHGKRLKASRLRSV..............IQRFI-kmesesisatkrdetypiltpy.................
Q753U0_ASHGO/1-413               ...................................................................................................MNAEQGDFVDDSQDEDDQiipvglsESd...aSEVHNMINSDLS.DAISSLDDERDSDWENGTGEEFE-.....-----NSVAN-....DPILNKVISSRVH.ESTPVPPI..NREVGAREATLeqi.....rasQMREQIDR..SLIDNI-EKLERLQKQINSSPEKPWLRSTDVVE----......ERRQAISAKIV.NPVPKRLLEYLARD-RVGSNKDWYFLTHNAIYQEPT--------LT.ELFLGSRPLL------....-...---...-SIRDLYLQFGASEDALDAE.FKIl.....eCN----SYEQLNNRAPLELm.cYEIERHIPFSAN.DQLEL.-----........SLRYFIL.FILDRKVFDCVELDTewCATLWEKH...K.A--.....--IDRIAVYLSVVPKDC..Y....FLHYRATRLLP-LKDE---------------LLCKLFIGSQ-...----.---PQEVIKQFDTLLENDDWFQILYFM.....................-----------.---------................--LLVNGLPDYPLg..........gI-.RIWQYFKD............................RIYDMNIDNV-SSI..ELSL----------LK..SYVNMCT----------..............------syk....................................
G0VH93_NAUCC/89-432              ......................................................................................fkddnishkevei------------------.......--.....------------.------------------------.....-----------....-------------.--------..-----------...........KQFDLGRS..FD-KKLATNISKLDELIKLAEKSPLKSPVVNLDIDKA......KNAYRAQLKYK.GNINEHIVDMVVRETISGQFKDWHFIDSEYNFKLLDPILDSDDFFYlNEIQMTEK-------I....K...KQF...PTLHELCLALGCNKVKLNNI.HIS.......-KEDLLQYDNLVELTPTENv.mKLICYYGSDPL-.-----.-----........FNKIFIC.LILDRKIYESLFCDSliCTTIYCKLilqN.DPD.....NESLFLQDYLQVVDKGN..Y....FLHYRLIRLLPNLKNA---------------LIERLFKENQ-...-DTK.L---AQFVKTFNKLFDEKMYRDLLYFV.....................-----------.---------................--LFIYGSDEMPF...........gNS.KTTEYFKD............................CVYDMTQDGT-NDV..ELSL---MKGVLNLF-..-----------------..............------yqine..................................
E7KSD9_YEASL/1-517               ...................................................................................................MDGALINSVLYVSPRNGA.......-H.....YFVELTEKHLLA.FEMLNSMCLLENYDHVLLFLECQ-.....FGKSHNLAVIP....FDIILVLFTLSTL.SEYYKEPI..LRANDPYNTSR...........ETLSRRAL..KLLQKYLAILKEFDSEQYNLYDLELLRCQFFLAIDTL......TPKKQKWSFDR.FRRTKSEKGVTYRQNASVDPELDQAKTFKNPYRSYISCLEQRNTIL.GNRLLNLKLNEPGEFI....N...MIL...WTLSNSL------QESTPLF.LSS.......HEIWMPLLEILIDLFSC--...RQDYFIQHEVAQ.NVSKS.LFVQRls....esPLAVFFE.SLNTRNFANRFSEYV..FLNCDYKL...P.SDN.....YATPVHPVYNG--ENTI..V....DTYIPTIKCSPLYKSQKSLALRRKLIGSCFKLLLRVPDGHRL...ITPR.IVADDVIQGISRTLASFNDILQFKKFFmtenls........qesyfipLLAEGTLSEIL.KDTQECVVI...............lTLVENLSDG-VSF............CN.EVIGLVKSk.........................cfAFTEQCSQTSYEEA..VLNIEKCDVCLLVLLR.yLLHLIGTEAILDAKEQLe............mLHAIE-k......................................
Q6CYC9_KLULA/1-375               ...................................................................................................MLSNDEDEVVASSDDGLY.......--.....AKIWDIRDEELD.DNGKNSDHFSDPGESFLLSSDDAM.....--------LPT....DRVLNNIMSSNAHiGTKRRRST..DRE-------Klw.......eeWHKSLKSS..MEINNMTMELKSFTDKRPDVQASQRKNSPHY------......DRQKQIAYSIK.RNIPTSLLTELAAD-VSDSTVDWYFLREDPDFSVVP-------SRY.STFLGKRLSI------....-...---...-PLDDLYKKFGADLRANIEY.TNC.......---------PYGKLIPVETm.cGLIESNNSDSVQ.-----.-----........AFKHFIK.FILDRKISGNLKTKW..VINMWNRF...T.---.....--CDKLSVYFEVTPRNF..Y....LMHYRLTRLIP-IESE---------------IVSKLFPN---...----.---DNDVITEFENLLDSQEWTSLLYFI.....................-----------.---------................--ILVLGTSALPF...........gPS.PRMTYIKD............................CILDLNSQNS-SKI..QLSIIKAYLT------..-----------------..............------vcski..................................
A7TFV6_VANPO/1-559               ...................................................................................................MNYAEPCSTSNEFTNKNDik...slPY.....YFVHLTDKHLSN.FETLNAMALIGNYADLLFFIESY-.....-ETSDTFVVPP....YDIIILLLTLVTV.SKYYKEAT..VRKNDYYVLTG...........KQLNKRSI..AILKNYIEILNEFDCGKYDRYSLELLRCQFFLAIELIf...nkEKRTDIRNRFK.RRRAEVEFEIEYLTSSVDENNDDDTIGFQNPYNSYIPFLDRNKTVL.GNKLFNIVLNKRDSFI....N...LLI...WTLSNSL------EEDTALY.LSS.......QEIWMPILQMILDIYLL--...RHDYYIQNELTN.KGNSH.FFSREls....rsPIGTLLR.SIGEVDFIERFCESV..FINCSDRN...D.ILS.....YRTVMQRIYQN--ENVI..S....NAFLPRVKYSNDYKMLKSMSIRRKMIGLCFRLLQDLDDDERL...ELPK.MSTNTLGDSIIRCVINFDNIKQFKMFFytemis........kelfflpILAEDCILKLS.ENYLENNREt..............lDLCSNFNNS-KAF............FQ.ILVELINDgyfyipelkcndndaydksnnkekndenNKIDAKIKKSLYKK..YITIMKADICLIVLLR.fFIYENSNMNEIKALSSFn...........nfLARV--kkldserlne.............................
E7KBP7_YEASA/1-360               ...................................................................................................MGSVNSSPNEEFETVPDTqi...sgFDsplipTSVGSYFRDDDD.DEKVHPNFTSDPENDSLNSDEEFSslensDLNLSGAKAESgddfDPILKRTIISK--.RKAPSNNE..DEEIVKTPRKLvny.....vplKIFNLGDS..FD-DTITTTVAKLQDLKKEILDSPRSNKSIVITSNTV.....aKSELQKSIKFS.GSIPEIYLDVVTKETISDKYKDWHFISENCHYEQLMDLEMKDTAYS.FLFGSSRSQGKVPEFV....H...LKC...PSITNLLVLFGVNQEKCNSL.KIN......yEKKENSRYDNLCTIFPVNKm.lKFLMYFYSDDDN.DDVRE.F----........FLKAFIC.LILDRKVFNAMESDHrlCFKVLELF...N.E--.....--AHFINSYFEIVDKND..F....F-----------------------------------------...----.---------------------------.....................-----------.---------................-------------............--.--------............................--------------..----------------..-----------------..............------ftl....................................
G0W7I9_NAUDC/1-538               .........................................................................................mrpscsrsvd----------YVIGNKSNer...rlPH.....YFVELTERHLGV.FEVLNSMCLLDNYDHILFFLECQM.....-VNTKTLPIPP....YDICLVLLTLATT.SNYYKADI..LQASDAYNFTR...........QSLDQRAL..KILRFYIRILLEFDTSKYEQYDLEFLRCQFFLVIDTLs....pKRAYRNIDRFK.RRKVEN-SKLIYGESISI--NEDELKDLQNPYRSYLSSLERKKSVL.GNTLINWKLTQPGEFI....N...MIL...WTLSNSL------QDDPALY.LSS.......HDVWMPILDIILELFNL--...RQKYFLKNEIGK.GISAD.LCVQRls....esPLSRFFQ.SVDSIHFTSRFCDYM..FINCDYSL...KgSDN.....SSTSIHPVYHG--ENQL..S....KLYVPRTKYTKVYKARKSFQLRRKIIGSCFKLLIHVPDKHKL...ISPRgMSSNDIVDGISRTLATFQNIEQFRSFFlsdsls........qevffipLLAEGTLAEII.ENHRQHQEEgpk..........tsiKVVKYLGDT-EQF............LL.EFISLFEK...........................gFMVPYCDKKITEKV..ILEIKKGDICVLVLFR..YLLHLIPSKKLKCVKSF..............------nhfievlkwndskrldvantq..................
H2AT47_KAZAF/1-162               ..............................................................................................mtsct-----RSINHVNGYKDEK......lPH.....YFVEVTLKDLNN.FEILNSICLLDNFDQMLYFLESQIntiqmKDGKRILAIPS....YDVLIVLITLATV.SEHSKEQL..LRASDPYNFTR...........IPLNKKAL..SIIEHYLSILKNFDTTLYAGYDLELLRCQFFLMVDNL.....lP----------.----------------------------------------------.----------------....-...---...--------------------.---.......-------------------...------------.-----.-----........-------.---------------..--------...-.---.....-----------------..-....------------------------------------------...----.---------------------------.....................-----------.---------................-------------............--.--------............................--------------..----------------..-----------------..............------ksfnqlesit.............................
B5DT85_DROPS/110-253             ..................................................................................sasendeasewvlnfer------------------.......--.....------------.------------------------.....-----------....-------------.--------..-----------...........--------..-------------------------------------......-----------.----------------------------------------------.----------------....-...---...--------------------.---.......-------------------...------------.-----.-----........-------.---------------..--ICGGVN...E.SSN.....FKLRCVRMLMKAGTEAD..L....FMRVDKSKTYDEFKGN---------------FLKTFGRSNS-...----.---TADVVLLLKETFFNPEKNSVMGYI.....................-----------.---------................-----LRMEEIAM............RA.DIEEKLTV...........................qFIIDGFRDRSSSIA..LLYSASTIGK------..-----------------..............------lkelar.................................
S6E807_ZYGB2/1-511               ...................................................................................................MGYADS-VEFIKGNNSVG......lAH.....YHVELTEAQLGT.FETLNSICLLDNFDHLLLFLECQL....yD--GLNLTVPP....FDIFLVLLTLATV.SDHYKDHS..TRSNDPYNASR...........APLNKRAL..KILFFYLERLKEFDTGKYGRYELELLRCQLFLASDSLs...pqRKRFDRPRKLR.KTVANTVYSCE----VVDVGEN----DFKEPYKSYISCLGQKSTVL.GNRIINSQLSYPGEFI....N...MIL...WTLCNSM------QDHPALY.LAS.......HDVWMPLLGIILDLLEL--...RQDYFVSQESQA.KNMRK.AEYVQkl...sqsPVAVFLE.SIDSLQFTDLFCEYI..FSKCDYLS...A.NNG.....REALVHPVYHG--EATL..S....NTFHLRIKYTKSYKIQKSIALRRKLIGIAFKLLSEVPSGHRL...VYPR.MEADDMINRISVILSEFNNLEQFRAFFsgnpt..........ssyflpLLAEGTLLQLC.HTYKNTSDPl.............swVIISDLLSGADAF............LD.KCISILET............................GLFIPWDNETPQDS..ILDICKADTCLLVLIK.tFVRLSGVA---------..............------lgsakfeamlsavkkv.......................
S6EHA9_ZYGB2/95-381              ...........................................................................lrkpsilpggqddnrtrllsqlqn------------------.......--.....------------.------------------------.....-----------....-------------.--------..-----------...........--------..-------------------------------------......-----------.KQVSPQYLDLIVKESISGRYIDWHFITENSEFQDVS----IEQELL.ADEKGKIVQEDIRALY....P...---...-SLKCFLNSIGVSDLTMRSLeAPSp.....kPLTANRRYDSLCAISPVES...------------.-MMRA.FKTYSdc...gtfFLKSLIC.FILDRKIWESMECDAhwCHNILAEF...T.T--.....--QQVLDEYLMLVERRD..Y....FMHYRFVRSFPHLQLA---------------LIRQLINPLK-...----.---TQAIMEEFERLMEEKSYQPLLYFT.....................-----------.---------................--LLVYGSRLMPF...........gNS.STTLYLKE............................CTEDLCNEST-NAV..ELSL------------..-----------------..............------lrgilgl................................
K0K7N9_WICCF/17-114              .........................................................................................eellrtfinv------------------.......--.....------------.----------KQYDKLLFFLESTL.....FNNAPTLNCPS....PFVINCLFTLATL.GEYNNAGL..IRKNFEKPLSQ...........QPVSVRAI..NILRRLVNIVKELDEDVKDEK----------------......-----------.----------------------------------------------.----------------....-...---...--------------------.---.......-------------------...------------.-----.-----........-------.---------------..--------...-.---.....-----------------..-....------------------------------------------...----.---------------------------.....................-----------.---------................-------------............--.--------............................--------------..----------------..-----------------..............------sn.....................................
NSE6_SCHPO/1-478                 ...................................................................................................MNASNNISKFPDLDNSSK.......--.....-----LIDHILD.SDDSEELDELPDISSLVPSARAQSrkqylKNDSSNSSTYRw..nIDLLSSTATIDDS.VAKRRKLA..VQNLLQYDSTQ...........--------..--TFQTGDEIDELIGKSVGSNVLNVLRSNPIYDDDL-......RYEYCSNSKAR.VPDWNTLKAECLKDNDLEFNEGIIPTTFGDLLSAKLVPLDIALSIC.S---LQFFRSLGDTTC....S...EWI...ANLEKIFYSYKSSSNNLNQI.VRF.......------IFETTADMIGIDLa.kRQVPIQLERTSA.SENLK.SNLKI........KVINFLK.CCGTLYRFSDDTVRFemIQDACRIL...I.DNQ.....VGSFCKWQFSQFMELPI..S....LNPDFLISNIHKVSES---------PRVWVTILSSLSRSCQK...FRKK.IAFTLFVGKQSKN--DDSDFSSLCQRL.....................----DEISASC.NNDYTTLLYq.............irTFGYAVDEKHFKT............NE.RLECLLEK...........................lRKIDLTISGSTDHL..LLSRCEVKDCIHRLFMvlYYLNTNSAPELERI---..............IE----sdlp...................................
E7NLB7_YEASO/1-325               ..................................................................................................m------------------.......--.....------------.------------------------.....-----------....-------------.--------..----XQYNTSR...........ETLSRRAL..KLLQKYLAILKEFDSEQYNLYDLELLRCQFFLAIDTL......TPKKQKWSFDR.FRRTKSEKGVTYRQNASVDPELDQAKTFKNPYRSYISCLEQRNXIL.GNRLLNLKLNEPGEFI....N...MIL...WTLSNSL------QESTPLF.LSS.......HEIWMPLLEILIDLFSC--...RQDYFIQHEVAQ.NVSKS.LFVQRls....esPLAVFFE.SLNTRNFANRFSEYV..FLNCDYKL...P.SDN.....YATPVHPVYNG--ENTI..V....DTYIPTIKCSPLYKSQKSLALRRKLIGSCFKLLLRVPDGHRL...ITPR.IVADDVIQGISRTLASFNDILQFKKFF.....................---------MT.---------................-------------............--.--------............................--------------..----------------..-----------------..............------enlsqesyfy.............................
J7RGY0_KAZNA/159-485             ................................................................................................skl------------------.......--.....------------.------------------------.....-----------....-------------.--------..-----------...........--------..-------------------------------------......-----------.----------------------------QNPYKSYISLLTKKEHVL.NNQLLHLKLSKRGEFV....N...MLR...WTLACSL------DERVTYF.MSA.......HEIWDPIVNLLLDLLDL--...RQKYFVLNEITL.SKKKKrTFVQRls....esPSVKFLK.IIDTFHFGPLFTEYL..FTGCNDDR...T.---.....RNKTIKPVYND--ETQL..S....QAFVPRFKYPKSYILEKSMKLRKRLLVACFNLLITVPRGHRL...CTIH.LETDDFLNNLSWELIGLKSIEYFQAFFktyd.............rereLAFMPVINEKI.INDITDLKFn.............lvDQIVSIRNFLKEW............TS.VIHSYLLL............................KLQELSK----AGV..VLEIYQIQTCLLALFE.yFEFIH------------..............------ekdgikkskfvcilrdiit....................
I2H2P8_TETBL/1-516               ...................................................................................................MQCSSSQSFVLGKERKNN.......PH.....YFVDLTEDILNV.FDILNSMCILENYNDLLLYLESNL....mSIDHKKLVVPP....FDVFMILLTVCTI.TPNYKNNI..IQENDHYNTTL...........TLLNRRVQ..NILKMYIKIVKDFNTSKYEVYDLELLRCQLFLMVDSLi....pSKHTISTNNNK.RKNKNNSLE-----------EN--KLFFPNKYESYVYCLDKNIETL.GNTLLHLVFHKYGEFT....N...CIL...WTLVNSM-----SNTNENFL.TTI.......-EIWIPLLNIIFDILEL--...RHEYFIMNELRK.ELPKS.IF-DEls....esPLAKLFKmFVVSHNFSTRFCEYI..FIECEGLK...T.SNS.....LNYRPHPIYHG--ENTF..N....NTYVQRVNYSKRYKLEKSFIFRRRIISLCYKLVSDLPRSKKL..lSDPR.MNKSTLTDHIVDSLLKLQDIVEFKTFFksddllqdigylpylaqktffVIRDQVLYPET.HNQYPTFNRdt...........eecNFVENFGED-DKF............LE.ELLDLVEEs..........................eDLFTNFNGQPFEKA..FLLIEKSKICLVTLIK.yFLYLECND---------..............------tsdlnhilidsl...........................
G8JMX5_ERECY/8-403               snsedeerlvqlqlsenddqdevinridsdlsdnisslsgdnynedpsqdvlndpilqsmgnksdplyiydsedeypfkykvrsneddpslpitrkdvd------------------.......--.....------------.------------------------.....-----------....-------------.--------..-----------...........--------..FNLLSNIEKIEEVHKDIETSPEKQISALSSIIK----......QREDMIKLSIK.NPISQQLLDFLVRD-KLETTKDWYFITDSPTYQEPS--------LL.DKFSGKQKTY------....-...---...-GIEELYVQFGVCKAKLDPS.FAI.......--TNYKNFDQMNNRVPVELm.cDEILRHVPTTNK.RDIA-.L----........SLRYFIL.FILDRKVFESDALTMswIVDTWIKH...R.---.....-FSDHLDVYLSLVPKDC..Y....FLHHRFTRLLP-IKSE---------------LIKKLFSDLT-...----.---PQAVAQKFDELMDQKNWFQMLYFI.....................-----------.---------................--LFINGITELPK...........gSN.GIWHYFRD............................CIYDMNIDNV-SSI..ELSVLKS---------..-----------------..............------yinlcin................................
NSE5_YEAST/1-517                 ...................................................................................................MDGALINSVLYVSPRNGA.......-H.....YFVELTEKHLLA.FEMLNSMCLLENYDHVLLFLECQ-.....FGKSHNLAVIP....FDIILVLFTLSTL.SEYYKEPI..LRANDPYNTSR...........ETLSRRAL..KLLQKYLAILKEFDSEQYNLYDLELLRCQFFLAIDTL......TPKKQKWGFDR.FRRTKSESGVTYRQNASVDPELDQAKTFKNPYRSYISCLEQRNTIL.GNRLLNLKLNEPGEFI....N...MIL...WTLSNSL------QESTPLF.LSS.......HEIWMPLLEILIDLFSC--...RQDYFIQHEVAQ.NVSKS.LFVQRls....esPLAVFFE.SLNTRNFANRFSEYV..FLNCDYKL...P.SDN.....YATPVHPVYNG--ENTI..V....DTYIPTIKCSPLYKSQKSLALRRKLIGSCFKLLLRVPDGHRL...ITPR.IVADDVIQGISRTLASFNDILQFKKFFmtenls........qesyfipLLAEGTLSEIL.KDTQECVVI...............lTLVENLSDG-VSF............CN.EVIGLVKSk.........................cfAFTEQCSQASYEEA..VLNIEKCDVCLLVLLR.yLLHLIGTEAILDAKEQLe............mLHAIE-k......................................
C5E4U6_ZYGRC/2-371               .......................................................................ssdsdedaiifrqnvndneldsssssss------------------.......--.....------------.------------------------.....-------STDE....DDRLLQTLK-RTS.YSSRRVTR..SSPIKKSKSVQ..........iQKFDLGRN..FD-PQLASSLDRIQNVKDEVDNPST----VTTVKEQK......SNTVRSRIKPR.-DASSQYIDLIVRETISGRYIDWHFISNDTRFEDVD----IDDELI.EDSDNHAVRD----AI....R...RKY...PTLLELIESLGADLSLLQED.KPL......tRK---RDYDSLSEMTPVDSm.mRAIGCYQDDKQ-.-----.-----........FIKYLLC.FILDRKIWESQDCDDdwCSQMLESV...G.D--.....--EQIIDFYLSLVDPKD..Y....FMHYRLSRCISRLQSP---------------LIHRIIRP---...----.----ITIEEEFTQLIEDKNYESLLYFT.....................-----------.---------................--LFVYGSHEMPF...........gPS.SRTQYFKD............................CVEDMCNEGT-NAV..ELSL------------..-----------------..............------lrgllslfl..............................
S9VVH5_SCHCR/172-477             .......................................................................................fevvacsnlipp------------------.......--.....------------.------------------------.....-----------....-------------.--------..-----------...........--------..-------------------------------------......-----------.-------------------------------------------SII.SCVLVYRFFN---SFYspprS...TWL...ECLKTYL--HSNIQSKRDSG.LDV.......NF----FYRQVCQKVGFNTq.kRYQSVRSETISP.KEVCS.IVLNDssdvnffvQCCQLMY.PICPQKLQSIIVQDV..FRCLLDIK...-.---.....VGHSCRLSFMKFMELTI..TsekpHFFYDLVRLSD-------------QPPVWVSILSSLPSNSPRvvhFRTN.LAIHWFLGTLPEPAF---ILSSICEQL.....................----DTLLDRCrNEDYTDLLFl.............tmTFSYTVAGLDLKR............SE.NLSLILEK...........................lRKLNLAIPGTTEHL..LLSRCEVKDYIHRLYM.vIYYENSDVY--------..............------selert.................................
G0W780_NAUDC/330-473             .........................................................................................ennsdeiqmn------------------.......--.....------------.------------------------.....-----------....-------------.--------..-----------...........--------..-------------------------------------......-----------.----------------------------------------------.----------------....-...---...--------------------.---.......-------------------...------------.-----.-----........-------.---------------..--------...-.---.....-KGNFIKIYFEVVDREN..Y....LLHYRLIRLIPELQKD---------------IINHLFENTVK...NGNG.GDDNIRIVEEFNNLFDNKQYHKLLYYI.....................-----------.---------................--LLIYGSDLMPF...........gHN.KTTEYFKD............................CIYDMTVEGN-NEV..ELSI---LKGIL----..-----------------..............------nifykitdkivdvnd........................
G8BZ47_TETPH/5-541               ...........................................................................................ldtscesv---------EYTNNGE-Dp....elPH.....YLVRLSDDVLRN.FEVLNSMYLLDDYDGLLMYMETQ-.....-IDEKSFAVPP....YDIVIVLLTLCTV.SNHYKDEM..VRANDLYNITR...........QQLSKRAI..QLLRKFVQILRDFDLEKYNRYTLELLRCQFFLAIDSFni.rraQYSFDRVRRIR.TPNAIVYTE--LSAEEIDSANEKYIATIEDPYKAYHSSLKQKFSVF.DNNLINLRLSEKGEFI....N...MII...WTLSNSV------QKEENLF.ISS.......HDIWLPLLGILMNIFDL--...RHCYYVDRQINE.NVDAS.LKVQLlg....tsPLALFLK.SLDSMQLSQRLSEYI..FINLSYER...D.-DS.....YNTYVHPVYYE--ENTF..S....KQYISRINYSENYKYIISMAMRRKLIGLCFKLLLNVPKGHKL...VSPR.LVPDDFMKSIVKKLCLFDNINQFKAFFyivdls........helffipLLAEMTIGELY.HDMNPSKIK................DQLQIVDYL-DNF............NK.FLEYSIKLidqgfftmp..........idnssnnvsSDSDSNDENSDDKIkyVSPLQKIDICFSVVLR.yAVHLN------------..............------ddgleksnialfeqfiravns..................
E7LYN6_YEASV/1-517               ...................................................................................................MDGALINSVLYVSPRNGA.......-H.....YFVELTEKHLLA.FEMLNSMCLLENYDHVLLFLECQ-.....FGKSHNLAVIP....FDIILVLFTLSTL.SEYYKEPI..LRANDPYNTSR...........ETLSRRAL..KLLQKYLAILKEFDSEQYNLYDLELLRCQFFLAIDTL......TPKKQKWSFDR.FRRTKSEKGVTYRQNASVDPELDQAKTFKNPYRSYISCLEQRNTIL.GNRLLNLKLNEPGEFI....N...MIL...WTLSNSL------QESTPLF.LSS.......HEIWMPLLEILIDLFSC--...RQDYFIQHEVAQ.NVSKS.LFVQRls....esPLAVFFE.SLNTRNFANRFSEYV..FLNCDYKL...P.SDN.....YATPVHPVYNG--ENTI..V....DTYIPTIKCSPLYKSQKSLALRRKLIGSCFKLLLRVPDGHRL...ITPR.IVADDVIQGISRTLASFNDILQFKKFFmtenls........qesyfipLLAEGTLSEIL.KDTQECVVI...............lTLVENLSDG-VSF............CN.EVIGLVKSk.........................cfAFTEQCSQTSYEEA..VLNIEKCDVCLLVLLR.yLLHLIGTEAILDAKEQLe............mLHAIE-k......................................
G0W780_NAUDC/3-309               .kkttqskiqqdntssdssldelleddeddedeteeddfilskiikqkplkdvfqdnddddddddnerkkrkrinplgylnnkskfipikqfdlgknyd------------------.......--.....------------.------------------------.....-----------....-------------.--------..-----------...........--------..---TKIVSSMEKLNELIDLANNSPIKSSVVDLAFDKS......KKTYEERLKLVgTRINDSLIDMILKEHISFKYKDWHFIDTNYDPMIISEIFDDDELTF.F----NLNKLKIAEMI....K...LKI...PNLNEFMIKCGCNMTKLNSL.RISstlsennVIETFNQYDNFVEICPMEDi.mKFLCYYDDDPN-.-----.-----........FIKIFIC.FILDRKVYETLFLDSicCTNIYQN-...-.---.....-----------------..-....------------------------------------------...----.---------------------------.....................-----------.---------................-------------............--.--------............................--------------..----------------..-----------------..............------vilkrtpq...............................
K0K7N9_WICCF/216-303             .................................................................................sldrksyyilrnerfdia------------------.......--.....------------.------------------------.....-----------....-------------.--------..-----------...........--------..-------------------------------------......-----------.----------------------------------------------.--------L-QGDGFW....N...AVA...WALQCSS-------TKDNLN.LEA.......WNVWKPILELIFDIIEIDL...--DQFITRKTNN.EDDE-.-----........-------.---------------..--------...-.---.....-----------------..-....------------------------------------------...----.---------------------------.....................-----------.---------................-------------............--.--------............................--------------..----------------..-----------------..............------ngepalfknt.............................
E7KML7_YEASL/1-461               ...................................................................................................MGSVNSSPNEEFETVPDSqi...sgFDsplipTSVGSYFRDDDD.DEKVHPNFXSDPENDSLNSDEEFSslensDLNLSGAKAESgddfDPILKRTIISK--.RKAPSNNE..DEEIVKTPRKLvny.....vplKIFNLGDS..FD-DTITTTVAKLQDLKKEILDSPRSNKSIVITSNTV.....aKSELQKSIKFS.GSIPEIYLDVVTKETISDKYKDWHFISKNCHYEQLMDLEMKDTAYS.FLFGSSRSQGKVPEFV....H...LKC...PSITNLLVLFGVNQEKCNSL.KIN......yEKKENSRYDNLCTIFPVNKm.lKFLMYFYSDDDN.DDVRE.F----........FLKAFIC.LILDRKVFNAMESDHrlCFKVLELF...N.E--.....--AHFINSYFEIVDKND..F....FLHYRLLQIFPHLQSA---------------LLRRRFSEKQG...RTET.I--QQNIIKEFNEFFDCKNYKNLLYFI.....................-----------.---------................--LTMYGSKFIPFg..........pKC.QVTEYFKD............................CILDISNETT-NDV..EISI------------..-----------------..............------lkgilnlfs..............................
G8ZU95_TORDC/80-398              ...............................................esvefksydlgrhfdpristsldkvqaltrlandlpvksesktifegkvpaf------------------.......--.....------------.------------------------.....-----------....-------------.--------..-----------...........--------..-------------------------------------......---------KN.RDVSSHYIDLILKESISKKYLDWHFITENTQFEEQP----------.----PSSVLFGPDENL....F...KRY...PTLESLLVAFGVGRDTLDFI.FMEk.....sPLTNSRQNDTLCKLSPFDTm.iNAFACYQDQTEQ.-----.-----........FAKYFIC.FILDRKVYESMFCDTiwCSKIYKTF...-.---.....SADDFMQQYVSLVHSQD..Y....FLHYRLIKLIPAAQDL---------------LIRRLFSEGEF...L-AG.EQARIKLVQEFNDLFDKRRFQQLLYFV.....................-----------.---------................--LTIYGSKYMPF...........gDT.DVTLYFKD............................CIADLFNASA-SDV..ELSL------------..-----------------..............------lngflsifi..............................
G0VJA4_NAUCC/1-511               ...................................................................................................MSCSKSISYVLGDKKSND......lPH.....YFVELTESHLAV.FEMLNSMCLLDDYDHLLFYLECQ-.....INETKILTIPP....FDICLILMTLVTI.SGHYKEQF..LRTSDTYNFTR...........ETMNNRAI..KILRFYLKVLRDFDTDKYQQYDLELLRCQFFLAIDT-......LIPKTLRKKFF.RSKRMKVDTSRVLYVEKLEDDTISLGTIENPYRSYISCLEQKKTVI.GNTLLTLKLSEPGEFI....N...MIL...WTLLTSL------QDDTALY.TSC.......HDVWIPLLDILIDLFDL--...KHKYFLRNEIVR.GISAT.LFVQRlt....esPLALFFR.SFGTTQFTARFCEYV..FVNCSYNL...EyDDD.....FKTEIHPVYRG--ENRL..S....NLYIPRMRYTKMYKIRKSLSLRRNIVGACLKLLVTVPNKHIL...TSPR.IASDTLIDQICVTLAKFSDVDQFKSFFftdsls........qelyfipLLAEGTLAELF.YNSGKLVKNlde.........kqplRFMENLSNV-DNY............LL.YCADLFEKg..........................fFMTESNQHIT-NVT..LTEMRKTDVCLLVLLR.yLLQ--------------..............------femnhaiisl.............................
Q6FWW8_CANGA/1-360               .......................................................................metvfdsendeplvelsdvddfefedgd------------------.......--.....------------.------------------------.....-----------....DPILKKMKL----.DVKPESSS..DSE------GE...........VVLQETDV..HPYMDFLQKLNKIQAGEVGEKRDIKRDKSIVELQHEE......LVKQLKSAGTF.TSVPDRLIDHISSEVLSDKFRDWHFITQECRDIDNT----------.----------------....-...---...-TLSSMLDAFGVGNSADLLN.LKI......iASEYTKKYDSLSTIYPVGYm.lEELVDYYRRTLP.RAETP.LE---........YCHAFFL.FVLDIKIYDSHECDTswCEEVLDIL...T.QRF.....RQEEIFDVYLKVVELND..Y....YMHYRVTKLIPRMKSY---------------ILAKLFGTVD-...----.---TVTIVNEFNTLLDDKRYKELLYFL.....................-----------.---------................--LLVLGTRYVPR...........gKN.ETIKYFIS............................CVTDVYDDSQ-SNP..EISIIKNYLLVLQ---..-----------------..............------vld....................................
J4U292_SACK1/1-514               ...................................................................................................MDDALINSVSYVSPRESA.......-H.....YFVELTERHLLA.FEMLNSMCLLENYDHVLLFLECQL.....D-KSRNLAVIP....FDIMLVLFTLSTS.SEYCKEPM..LRANDPYNVSR...........ETLSRRAL..KILQKYLAILKDFDAEQYNLHDLELLRCQFFLAIDTL......TPRKQKWSFDR.FRRTKSENDVAYRPNASADPELEPSNTIKNPYRSYISCLEQTHTIL.GSRLLNLKLSEPGEFI....N...MIL...WTLCNSL------QESVPLY.LSS.......HEIWMPLLEIIIDLFNF--...RQDYFIHHEIAR.NISKS.LFIQRls....esPLATFFE.SLNTRNFANRFSEYV..FINCNYRA...P.SEN.....YATPVHPVYNG--ENTI..V....ETYIHRFKYSALYKSQKSLALRRKLIGSCFKLLLRVPDGRRL...ITPR.IIADDVIQGISRTLASFNDILQFKKFFmtenls........qesyfipLLAEGTLSEIF.KDTQECVVI...............lTLVESLSDG-VSF............CS.EVIDLVRLk.........................cfTFTEQSKRISYEES..ILITEKCDVCLLVLLR.yLLH--------------..............------lvdvetitgttenlrmlrt....................
Q6CWU9_KLULA/1-497               ...................................................................................................MASQSH-KYDLGRNELNK.......PD.....YYVELTEKHLSD.FEIWNSLCSNESYDMLLYLCEQY-.....-LNMGRFPVIP....SEVIAVLFTLASI.GDHNKGSL..IKKADPFDTGR...........ELLTRRSM..KLLETLLDILQTFDTDLYEIYDLELLRCQFFYFIDSIrpengrALVLDPLNAQS.SRATRRSFKLSSRSA-----EGGSLLSVEPLYGSYINLIGDDTSVF.KTTMVHSALSQEGSFW....N...GFS...WALSTFMIGHENEDQKTDWD.YEL.......AKAWLSVFKLIFIIYEL--...RQDYYIDSKTET.IEKS-.-----........PIFRLLE.AVDKKNQLKGLVQYL..FVGCVECE...-.---.....---ILYPVSPSLNDPST..S....NASFNQFHEDKDYRAAFSMDVRKDTLCVFVRFLDRYER--HL...QSYP.FTLDALYGTIVDALYSDLKISSFKQFFlscdve........kdrnlitTLVEKLLNKAF.SNVEPRRTFn.............ivNKMSNFEEV----............TS.ELMKLLRA............................--IDRSAAFNRSRI..SKRRIQMDFCIIILTR..LIITTHPQGNFEELLRV..............LTTFAK.......................................
E7QDU7_YEASZ/1-461               ...................................................................................................MGSVNSSPNEEFETVPDSqi...sgFDsplipTSVGSYFRDDDD.DEKVHPNFTSDPENDSLNSDEEFSslensDLNLSGAKAESgddfDPILKRTIISK--.RKAPSNNE..DEEIVKTPRKLvny.....vplKIFNLGDS..FD-DTITTTVAKLQDLKKEILDSPRSNKSIVITSNTV.....aKSELQKSIKFS.GSIPEIYLDVVTKETISDKYKDWHFISENCHYEQLMDLEMKDTAYS.FLFGSSRSQGKVPEFV....H...LKC...PSITNLLVLFGVNQEKCNSL.KIN......yEKKENSRYDNLCTIFPVNKm.lKFLMYFYSDDDN.DDVRE.F----........FLKAFIC.LILDRKVFNAMESDHrlCFKVLELF...N.E--.....--AHFINSYFEIVDKND..F....FLHYRLLQIFPHLQSA---------------LLRRRFSEKQG...RTET.I--QQNIIKEFNEFFDCKNYKNLLYFI.....................-----------.---------................--LTMYGSKFIPFg..........pKC.QVTEYFKD............................CILDISNETT-NDV..EISI------------..-----------------..............------lkgilnlfs..............................
I2H401_TETBL/8-423               ..............dsgdgsdmeiirdsqtddndddsliilndfkenpyeslldstddehdnnqfldeslagdaifslitqhkqstnldldknggnnik------------------.......--.....------------.------------------------.....-----------....-------------.--------..----------NepsikdskveiKQSDLGDD..FD-EELGKKMKRFRDISDDITTLKKRALDYEYRTDSN......NIALLKKQIKY.KEISNNYLEMVANETLSGKYKDWFFFTENSRFNEDI-L-----EDI.ENFSSKEIMLKYGDFK....KllvCFG...TNIKYLY------QDYNISD.LKY.......------KYDTLSILQPIDT..mKVIIGHYFIIDP.-IN--.-----........FKKFFPS.LLLDRNFYESLSIDDdwCTSFYNKI...T.P--.....--KIFFKNYFKVVNKTD..F....FLHYRLIRIIPSSKNL---------------IISLIFSTSV-...-EVK.DVEKNPVIEMFNYLIDEKNYKNLLYFI.....................-----------.---------................--LVLSGSNLVPF...........gSN.KYVDYFQS............................CINDISDENS-NEV..ELTL------------..-----------------..............------vrnilklfekv............................
G8BTX3_TETPH/2-431               .................................................................................................sn------------------.......--.....SFIHDSQDSSVT.DDVLRENIKINN--SIVLSSDSS-.....DSDLDSSFHIDv.gnDPILKTLKSRQKS.INQEESNV..LNLA------Gnnlf..kqvkiQQFDLGSNfdKNITKNLTVLNNESMASDGINDN-LLQANTFVSQAEIdt.kklISFLGKSTLKK.YHNIEYYINMLVNERVSSKYLDWFFFNQDSTITDIS-------DII.SNADFFLLGNNWPKLK....E...LILkkyPTISDLLMSIGVSNEKLERL.GDGn....clQLTTDRTYDPLAKLLPFDSv.lQIIAFYCHEKG-.-----.-----........FLKIYFA.IMLDRNFYELSNSYDnnLYDFLKIF...S.N--.....--EQILDSYFQLVSKDD..Y....FMHYRFSRMIPQYKNI------------LVNYLWKTDSDNID...E---.--SLEKLANEFNNLYDNSKYESLLYYI.....................-----------.---------................--LFIYGSDLLPIkmsvekdmisvnHN.NLKEYFIN............................CIHNSTGHLT-NDV..ELPL------------..-----------------..............------iknilgif...............................
#=GC seq_cons                    .....................................................................................................................................l....p......c..p......s.tt.h...-................h.......slhhhhhh......ph.pt.....pt...h..th...........t.hshts...h..pphhphlpchpstp.th.p..hhppphhhh.sp.......p.pht...h.p.tphsp..hshhhptt..sp.ps..hhs.ps.apphh.....p.thh.tph.hshhhtp.sphh....p...hhh....oLss.l......ppp.s.h.h.s.......tph...hh-.lhslhsl.....+..hah.p-.st.t..t................lthFhp..l.spphhpthpp.h..hhps.tph...s.t.........tphhssYht..-ps...h....hhah.hh+h.sthc.t...............lLtpl.pspph......t.h..pphlhp.hppLhs.pshpphhhFh............................................................l..hust.hsh.............p.phhphhcp............................phh-.sppts.pch...lpl...................................................ht.....................................
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