GenomeNet

Database: Pfam
Entry: Nterm_IS4
LinkDB: Nterm_IS4
Original site: Nterm_IS4 
#=GF ID   Nterm_IS4
#=GF AC   PF13006.4
#=GF DE   Insertion element 4 transposase N-terminal
#=GF AU   Coggill P
#=GF SE   IS_finder
#=GF GA   21.80 21.80;
#=GF TC   22.20 23.80;
#=GF NC   21.20 21.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   2996976
#=GF RT   Joint distribution of insertion elements IS4 and IS5 in natural
#=GF RT   isolates of Escherichia coli.
#=GF RA   Dykhuizen DE, Sawyer SA, Green L, Miller RD, Hartl DL;
#=GF RL   Genetics. 1985;111:219-231.
#=GF DR   INTERPRO; IPR024473;
#=GF CC   This family represents the N-terminal region of proteins
#=GF CC   carrying the transposase enzyme, DDE_Tnp_1 (that was
#=GF CC   Transposase_11), Pfam:PF01609, at the C-terminus. The
#=GF CC   full-length members are Insertion Element 4, IS4. Within the
#=GF CC   collection of E.coli strains, ECOR, the number of IS4 elements
#=GF CC   varies from zero to 14, with an average of 5 copies/strain [1].
#=GF SQ   134
#=GS H6RIM9_BLASD/23-116       AC H6RIM9.1
#=GS J9M7X8_ACYPI/266-358      AC J9M7X8.2
#=GS G0G0Y9_AMYMS/14-107       AC G0G0Y9.1
#=GS Q32A43_SHIDS/23-115       AC Q32A43.1
#=GS K4QVT8_9ACTN/1-94         AC K4QVT8.1
#=GS A0A0A6ZMN0_SHIDY/47-139   AC A0A0A6ZMN0.1
#=GS A1SV49_PSYIN/1-58         AC A1SV49.1
#=GS Q2JB40_FRASC/12-110       AC Q2JB40.1
#=GS YCHG_ECOLI/18-107         AC P30192.2
#=GS D2THB0_CITRI/18-112       AC D2THB0.1
#=GS Q2JGA9_FRASC/11-109       AC Q2JGA9.1
#=GS G8M9P4_9BURK/15-108       AC G8M9P4.1
#=GS A0A0A6ZX84_SHIDY/23-115   AC A0A0A6ZX84.1
#=GS K9TAD9_9CYAN/41-135       AC K9TAD9.1
#=GS A0A0D5V3J4_9BURK/18-115   AC A0A0D5V3J4.1
#=GS Q2JF90_FRASC/18-72        AC Q2JF90.1
#=GS A0A0A6ZRR2_SHIDY/50-142   AC A0A0A6ZRR2.1
#=GS A0A0D5VPK5_9BURK/18-115   AC A0A0D5VPK5.1
#=GS K0JXC5_SACES/22-120       AC K0JXC5.1
#=GS E8RKS3_ASTEC/8-101        AC E8RKS3.1
#=GS A4JLT1_BURVG/17-115       AC A4JLT1.1
#=GS D2PLH1_KRIFD/11-52        AC D2PLH1.1
#=GS A0A0A6ZN47_SHIDY/110-202  AC A0A0A6ZN47.1
#=GS Q8FSH8_COREF/18-117       AC Q8FSH8.1
#=GS A0A089PQX6_PLUGE/15-107   AC A0A089PQX6.1
#=GS X1XN69_ACYPI/17-109       AC X1XN69.1
#=GS K7RYI6_PROA4/18-116       AC K7RYI6.1
#=GS Q2J8F5_FRASC/15-113       AC Q2J8F5.1
#=GS Q7M7C3_VIBVY/18-112       AC Q7M7C3.1
#=GS Q8CM86_COREF/18-117       AC Q8CM86.1
#=GS F5XQ00_MICPN/13-105       AC F5XQ00.1
#=GS B2J1G3_NOSP7/1-85         AC B2J1G3.1
#=GS Q32AI1_SHIDS/23-115       AC Q32AI1.1
#=GS A8L4S2_FRASN/21-119       AC A8L4S2.1
#=GS A0A0A8EBC9_9ACTN/1-88     AC A0A0A8EBC9.1
#=GS Q32CS7_SHIDS/23-115       AC Q32CS7.1
#=GS D5W4U9_BURSC/21-114       AC D5W4U9.1
#=GS D2TH14_CITRI/15-108       AC D2TH14.1
#=GS Q82R32_STRAW/8-103        AC Q82R32.4
#=GS W6R4S3_9RHIZ/23-116       AC W6R4S3.1
#=GS C1DP19_AZOVD/1-55         AC C1DP19.1
#=GS A8L1S1_FRASN/24-123       AC A8L1S1.1
#=GS A0A0A6ZP97_SHIDY/23-87    AC A0A0A6ZP97.1
#=GS G8M7H6_9BURK/15-108       AC G8M7H6.1
#=GS A0A068R5X2_9ENTR/17-112   AC A0A068R5X2.1
#=GS D4ZHZ7_SHEVD/15-107       AC D4ZHZ7.1
#=GS A8KXP7_FRASN/18-116       AC A8KXP7.1
#=GS F8AXZ8_FRADG/23-121       AC F8AXZ8.1
#=GS G8M6F1_9BURK/15-108       AC G8M6F1.1
#=GS Q2J581_FRASC/11-109       AC Q2J581.1
#=GS H2FV62_OCESG/15-107       AC H2FV62.1
#=GS W6RHK1_9RHIZ/20-113       AC W6RHK1.1
#=GS W6RF99_9RHIZ/20-113       AC W6RF99.1
#=GS F9T0N1_9VIBR/17-109       AC F9T0N1.1
#=GS G4FUV5_9GAMM/25-118       AC G4FUV5.1
#=GS A0A0A6ZTU1_SHIDY/55-147   AC A0A0A6ZTU1.1
#=GS Q8E9X7_SHEON/15-107       AC Q8E9X7.1
#=GS Q7MJC7_VIBVY/18-112       AC Q7MJC7.1
#=GS W6R332_9RHIZ/8-101        AC W6R332.1
#=GS E0SL40_DICD3/21-114       AC E0SL40.1
#=GS W6RG65_9RHIZ/20-113       AC W6RG65.1
#=GS H6RVQ3_BLASD/11-104       AC H6RVQ3.1
#=GS Q5GZ11_XANOR/1-83         AC Q5GZ11.1
#=GS G2P482_STRVO/1-80         AC G2P482.1
#=GS K9U088_9CYAN/19-113       AC K9U088.1
#=GS K0JV09_SACES/22-123       AC K0JV09.1
#=GS A0A0A6ZVQ7_SHIDY/37-129   AC A0A0A6ZVQ7.1
#=GS Q8FLI0_COREF/1-91         AC Q8FLI0.1
#=GS Q32GW6_SHIDS/23-115       AC Q32GW6.1
#=GS B2JV26_BURP8/15-108       AC B2JV26.1
#=GS W6RRJ7_9RHIZ/20-113       AC W6RRJ7.1
#=GS A8L021_FRASN/17-115       AC A8L021.1
#=GS D2TQC4_CITRI/18-112       AC D2TQC4.1
#=GS A0A0A7A560_SHIDY/17-109   AC A0A0A7A560.1
#=GS K0JWE3_SACES/22-120       AC K0JWE3.1
#=GS F5XSB1_MICPN/11-91        AC F5XSB1.1
#=GS Q32FF6_SHIDS/23-115       AC Q32FF6.1
#=GS W6R5G7_9RHIZ/20-113       AC W6R5G7.1
#=GS K9ZE46_ANACC/15-108       AC K9ZE46.1
#=GS A0A089PQ08_PLUGE/15-107   AC A0A089PQ08.1
#=GS Q8CM19_SHEON/15-107       AC Q8CM19.1
#=GS F5XT14_MICPN/18-116       AC F5XT14.1
#=GS Q5QU56_IDILO/15-107       AC Q5QU56.1
#=GS G8MC69_9BURK/15-108       AC G8MC69.1
#=GS F8B083_FRADG/12-110       AC F8B083.1
#=GS Q7MLW1_VIBVY/18-112       AC Q7MLW1.1
#=GS D7C169_STRBB/10-102       AC D7C169.1
#=GS D2ASB5_STRRD/13-111       AC D2ASB5.1
#=GS D2TIW6_CITRI/18-112       AC D2TIW6.1
#=GS C1DHR3_AZOVD/11-104       AC C1DHR3.1
#=GS Q326Z2_SHIDS/23-115       AC Q326Z2.1
#=GS Q1LFQ5_RALME/20-118       AC Q1LFQ5.1
#=GS A8L643_FRASN/1-68         AC A8L643.1
#=GS A4JGL4_BURVG/20-118       AC A4JGL4.1
#=GS Q8FPL6_COREF/18-117       AC Q8FPL6.1
#=GS G8MQD6_9BURK/1-91         AC G8MQD6.1
#=GS Q8FRV1_COREF/18-117       AC Q8FRV1.1
#=GS A0A089PKE2_PLUGE/15-107   AC A0A089PKE2.1
#=GS B2JAP6_NOSP7/5-99         AC B2JAP6.1
#=GS V6KH62_STRNV/4-99         AC V6KH62.1
#=GS A0A0A6ZYA8_SHIDY/23-115   AC A0A0A6ZYA8.1
#=GS F8B6B6_FRADG/21-119       AC F8B6B6.1
#=GS Q32JF1_SHIDS/23-115       AC Q32JF1.1
#=GS A0A0D5EHH2_9BURK/17-116   AC A0A0D5EHH2.1
#=GS D4ZJM3_SHEVD/15-107       AC D4ZJM3.1
#=GS Q7ML52_VIBVY/18-112       AC Q7ML52.1
#=GS INSG_ECOLI/17-109         AC P03835.1
#=GS Q6D540_PECAS/17-109       AC Q6D540.1
#=GS F8AZF0_FRADG/12-110       AC F8AZF0.1
#=GS A0A0A7A128_SHIDY/17-109   AC A0A0A7A128.1
#=GS A8LF21_FRASN/21-119       AC A8LF21.1
#=GS A0A077LNH5_9PSED/17-118   AC A0A077LNH5.1
#=GS G2NZZ3_STRVO/10-103       AC G2NZZ3.1
#=GS E4N371_KITSK/18-116       AC E4N371.1
#=GS G0HGE0_CORVD/1-55         AC G0HGE0.1
#=GS G0G104_AMYMS/14-107       AC G0G104.1
#=GS C6WCS4_ACTMD/18-116       AC C6WCS4.1
#=GS Q32J58_SHIDS/23-115       AC Q32J58.1
#=GS A0A0A7A4L6_SHIDY/23-96    AC A0A0A7A4L6.1
#=GS D0LI35_HALO1/16-109       AC D0LI35.1
#=GS Q7MGY3_VIBVY/17-109       AC Q7MGY3.1
#=GS Q2JAY9_FRASC/18-127       AC Q2JAY9.1
#=GS M4NBA0_9GAMM/25-118       AC M4NBA0.1
#=GS E1VVQ6_ARTAR/18-116       AC E1VVQ6.1
#=GS Q82R31_STRAW/23-116       AC Q82R31.1
#=GS E0SFQ3_DICD3/15-107       AC E0SFQ3.1
#=GS A0A0A7A2Y2_SHIDY/23-115   AC A0A0A7A2Y2.1
#=GS D2TNL1_CITRI/15-108       AC D2TNL1.1
#=GS Q32E26_SHIDS/23-115       AC Q32E26.1
#=GS F8AYX9_FRADG/12-92        AC F8AYX9.1
#=GS Q82QY0_STRAW/23-116       AC Q82QY0.1
#=GS Q32CZ3_SHIDS/23-115       AC Q32CZ3.1
#=GS A0A0A7A0P6_SHIDY/23-115   AC A0A0A7A0P6.1
#=GS W6R4D8_9RHIZ/20-113       AC W6R4D8.1
H6RIM9_BLASD/23-116                  .......p-GHLGELTQIVPFEMVDAVLAKTGTVQQRV.RDLPSRVVVYLLLSAVLFAEC..GYRQVWDRMTAALDGL.............-PVPAPTPAALAAARRRIGAAPLRALFD..........
J9M7X8_ACYPI/266-358                 .......p-QEFSALSDLLSPELIDECLADTGTVTLRK.RRLSMEMMVWAVTGMALFRSH..SMTQLVSHLDILLPGK.............R--PFVAPSAVVQARQRFGEDVIRLMFE..........
G0G0Y9_AMYMS/14-107                  .......p-GHLGELTQIVPFEMVDAALAETRRMQQRL.RVLPSRVVVYLLLAAGLFTEV..GLSQVWTRLCAGLDKL.............A-VARPSPSALAAARVRVGAVPLRALFD..........
Q32A43_SHIDS/23-115                  ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCTVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
K4QVT8_9ACTN/1-94                    .......m------LTQAFPQSLVDEVLAETGRVQRRN.RLLPARLVVYFVLAMCLFSGQ..SYEEVARLLTTGLQGArr.........wrASWVVPSTAAIWKARSRLGVAPMRQLFA..........
A0A0A6ZMN0_SHIDY/47-139              ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
A1SV49_PSYIN/1-58                    .......m------------------------------.-----EKMVWAVVGMALFRKY..SMRQLVNQLDIILPNG.............E--PYVASSAVTQARKKLGYQAIES---is........
Q2JB40_FRASC/12-110                  .......r-ISIGVLARIVPRDLVDEALVETKRQERRT.RLLPARVMVYFTMAMCLFFDD..DYEEVMRKLAGALRWLgn.........wkGDWQVPTSGAISQARIRLGAAPLKLLFE..........
YCHG_ECOLI/18-107                    ....ppsa----QLFAEHLPTEWIQHCLTLSAHATVRR.RRLPGDMVIWMVV-----QNE..PITDVVRRLNLSADGE.............AGMNLLARSAVTQARQRVGAAPVEWLFR..........
D2THB0_CITRI/18-112                  ....ppsa----QLFAQHLPVEWIQHCLTLSAHATVRR.RRLPGDMVIWMVVAMAFFRNE..SITDVVRRLNLSADGE.............AGMNLLARSAVTQARQRVGAAPVEWLFR..........
Q2JGA9_FRASC/11-109                  .......w-ISLGVLTSFVSRDAVDGAIEATGRGARRSdTTIPPRVAVYFVMALALFADD..DYEAVACRLAATLDDLdv.........vgPRWE-PTSGGLTKARQRLGSAPLAELF-c.........
G8M9P4_9BURK/15-108                  .......p-TDLRRLAEHLPDEWIRRAVQATGTASIRR.RRLPAEQVVWLVIALAMYRHW..SISEVLDSLDLALPDE.............A-APFVSKSAVAQARQRVGEAPMAWLFE..........
A0A0A6ZX84_SHIDY/23-115              ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
K9TAD9_9CYAN/41-135                  qslglpfe--------NLLPSWEIQKVIDELK-VKYRR.RLFDPIVTLWTFLSQVLDVDK..SCHNAVSRVIAYLANQ............rVEIPSSDTSAYCQARSRLPENLLEKLF-g.........
A0A0D5V3J4_9BURK/18-115              .....lav----GYLALNCSLGEVKEALVKCGVHTRLR.RDMPREVLVYFVMAMCLYPRV..AYEEVFRLVIEGLRRIyg.........dqVRDAQVSKAAISQGRARLGWQVMRELFA..........
Q2JF90_FRASC/18-72                   .......h-ISLGVLTGLVHHDLVDDVLVETGRVEKRS.RKLPARVMVYFTLAMWLFFDD..----------------.............----------------------------ergg......
A0A0A6ZRR2_SHIDY/50-142              ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
A0A0D5VPK5_9BURK/18-115              .....lav----GYLALNCSLGEVKEALVKCGVHTRLR.RDMPREVLVYFVMAMCLYPRV..AYEEVFRLVIEGLRRIyg.........dqVRDAQVSKAAISQGRARLGWQVMRELFA..........
K0JXC5_SACES/22-120                  ........RVSLGVLAEVVSRDLIEEVLDETGKREQRT.RLLPAHVMVRFCQAMCLFFDD..DYEEVMRKLVGSLKSMgs.........wrGEWHVPSTSAVAQARQRLGSEPLRVLFE..........
E8RKS3_ASTEC/8-101                   .......h-VDLTALSRSVDVDWISQALAATGKASVRR.RKLPAEQVVWLVIALALYRHQ..SIADVAAHLSLALPDE.............VN-PDIAKSALTQARQRLGQAPLAQLFA..........
A4JLT1_BURVG/17-115                  ......li--SAGVLASVCPRTLIEEVLAETGKASQRE.RLLPAPAVVYYVMALALWREA..PLEEVLRVVCEGLQWLgg.........ghTEAVQASKSAISQARSRLGPEVMRQL--ad........
D2PLH1_KRIFD/11-52                   ..qaslgv------------------------------.---------------------..--------LDRWNCWN.............AAWSVPTVSAITQARKWLGRCVFPELFE..........
A0A0A6ZN47_SHIDY/110-202             ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
Q8FSH8_COREF/18-117                  ......li--SVGLLTRVFPADVVDEVVAQAGRTQQRS.RILPSRVMVYYTITMALNSDG..SYEDIYADLTDGLSWAcr........weeQAVPAPSRSAIFQARVRLGHEPMAALFA..........
A0A089PQX6_PLUGE/15-107              .......p-KEFSALSDLLSPELINECLVDTGVATIRK.RRLPMEMMVWAVTGMTLFRSL..SMNQLVSHLDILLPGK.............R--PFVAPSAVVQARQRLGADVIRSVFE..........
X1XN69_ACYPI/17-109                  .......r-NPLNTLADVLDPALISRCLEEAGTVTLRK.RRLTTDMMVWCLIGMALERKE..PLHAIVNRLDILLPGN.............R--PFVAPSAVVQARQRLGDDAVRRVFE..........
K7RYI6_PROA4/18-116                  .......l-VSVGVLSRVFPAHLVDEVITECGRTERRH.RSLPARVMAYFAIGMALDASG..SYEDVMAQLTDGLAWAsg.........wsQEFGLPSASAIFQARARLGAEPIRRLFE..........
Q2J8F5_FRASC/15-113                  .......w-ISLGVLTSFVPRDAVDEAIEATGAGARRSdTTIPPQVVAYFVMALALFADD..DYETVARRLAATLTDLdv.........vgPRWE-PTSSGLTKARQRLGAAPLAELF-g.........
Q7M7C3_VIBVY/18-112                  ......va--QLTTFSEHIPDEWVAKAATLSDKATIRR.RRLPSDMVLWLIVGMAFFRNE..SIAEVARRMNVCAEGL.............ADEELLAKSALTQARQRLGKAAPEWLFR..........
Q8CM86_COREF/18-117                  ......li--SVGLLTRVFPADVVDEVVAQAGRTQQRS.RILPSRVMVYYTITMALNSDG..SYEDIYADLTDGLSWAcr........weeQAVPAPSRSAIFQARVRLGHEPMAALFA..........
F5XQ00_MICPN/13-105                  ......ev--------QSFPAAVLDEVIEAAGVREVRY.RRLPARLMMVFTLACWLFMRS..GYGLVLSRLADAQALTgg.........gwGDWQAPGTGSITKAKAKLGAEPFKLLFA..........
B2J1G3_NOSP7/1-85                    ....masl-------------------TANIQTQEERK.RSLPAQLVVSLVIAMSLWSKD..SMRDVLKNLIDGLSEAwl........kvgKYWRVACKSAITQARQRLGARVMCKLFH..........
Q32AI1_SHIDS/23-115                  ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
A8L4S2_FRASN/21-119                  .......r-ISLGVLARIVPRDLVDEVLAETRRLEQRK.RLLPARVVVYFTMAMCLFFDD..DYDEVMRRLVGTLRWLgs.........wkGDWKVPSTGAISQARTRLGPEPLKLLFE..........
A0A0A8EBC9_9ACTN/1-88                .......m-------APVIPFELVDAALAETGRTERRV.RMLLSRVGVYFALAPGLFGHV..GARLVWQKLISGLAGP.............R-VPVPSEKALRDLRRRIDVAPLKALFE..........
Q32CS7_SHIDS/23-115                  ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
D5W4U9_BURSC/21-114                  ......pl--EWGRLGQHLPYEWIEYAVQASGSASVRR.RRLPAQQVVWLVIALALYRHQ..SISEVVDELDLALPAA.............-DASFVSKSAIAQARQRIGAAPLAWLFH..........
D2TH14_CITRI/15-108                  .......p-ASLSCFQRAIPLEWISQVLDSTNKASIRK.RKLPAELVVWLIVGMGLYRDR..SITDVVTKLDLVLSSQ.............E-GETLAASSVARARQRLSDEPLRELFT..........
Q82R32_STRAW/8-103                   .......p-GHLGELTQVIPFDLVDAVLDETRCVQRRL.RDLPSRVGVYFLLAMCLFPEV..GYRLVWHKLTAALTGV............gFEVAEPTAKALRDLRRRLGAEPMKRVFE..........
W6R4S3_9RHIZ/23-116                  .......s-AELSALSQAIDPDWIAQALATTGKASIRK.RKLPAEQVVWLVIALALYRHQ..SIPEVVAHLDLVLPDE.............VN-ADIAKSALTQARQRLGQAPLAHLFA..........
C1DP19_AZOVD/1-55                    ........------------------------------.----------MVLGMALFRDE..PVHEVARCLNICAQGL.............ASDQLLARSGVTEAHKRLGADPVESLFR..........
A8L1S1_FRASN/24-123                  .......q-VSVGVLVTAVPRDAVDEAVAACGVGARRAgGKLPPHVTAYLTLAMSLFPDD..DYAEVAQKVTGSLDRFgc.........wdAAWAPPSASGITQARKRLGRMVMAEVFE..........
A0A0A6ZP97_SHIDY/23-87               .rnpltsr-------GDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDVM----.............----------------------------pi........
G8M7H6_9BURK/15-108                  .......p-TDLRRLAEHLPDEWIRRAVQATGTASIRR.RRLPAEQVVWLVIALAMYRHW..SISEVLDSLDLALPDE.............A-APFVSKSAVAQARQRVGEAPMAWLFE..........
A0A068R5X2_9ENTR/17-112              .......p-ESIDAFSKNIPLEWVTEAVRETGCATVRK.RRFPAEQAVWLVLGIGLMRNR..SINDVCDKLELAFPDA............rGELPSLASSSITQARHRIGVEPLRHLFH..........
D4ZHZ7_SHEVD/15-107                  .......p-HQVETLADLLPLELIEEAYSLTETVTLRK.RKLTLESMAWLLIGMAIYNDK..SMAHIVNMLDIVDREG.............K--PFVAPSALTQRRKDLGEAAMKALFE..........
A8KXP7_FRASN/18-116                  .......r-VGLGVLAAQFPDALVDRVVAETGRRERRT.RDLPAALTLRYVVALALFPSD..GYDEVMRQVKVADDWLsd.........kaGPVKVPATTAITKARDRLGVEPVKLLFE..........
F8AXZ8_FRADG/23-121                  .......r-ISIGVLARIVPRDLIDEVLVETKRQERRT.RLLPARVMVYFTMAMCLFFDD..DYEEVMRKLAGGLMWLgn.........wkGDWKVPTTGAISQARTRLGAAPLKLLFE..........
G8M6F1_9BURK/15-108                  ....padp----SRLAEHLPYEWIERAVQATGVASIRR.RRLPAEQVVWLVIALAMYRHW..SISEVLDNLDLALPDN.............A-APFVSKSAVAQARQRIGEAPLAWLFE..........
Q2J581_FRASC/11-109                  .......w-ISLGVLTSFVSRDAVDGAIEATGRGARRSdTTIPPRVAVYFVMALALFADD..DYEAVACRLAATLDDLdv.........vgPRWE-PTSGGLTKARQRLGSAPLAELF-c.........
H2FV62_OCESG/15-107                  .......t-VEFHSLAEVLDPEIIQACLASNGVATVRK.RKLPMEAMVWAVIGMALFRGD..SVRQLINKLDIVLPQE.............V--DSVVRSAVTQARKKLGSDVVRDIFR..........
W6RHK1_9RHIZ/20-113                  .......s-AELSALSQAIDPDWIAQALATTGKASIRK.RKLPAEQVVWLVIALALYRHQ..SIPEVVAHLDLVLPDE.............VN-ADIAKSALTQARQRLGQAPLAQLFA..........
W6RF99_9RHIZ/20-113                  .......s-AELSALSQAIDPDWIAQALATTGKASIRK.RKLPAEQVVWLVIALALYRHQ..SIPEVVAHLDLVLPDE.............VN-ADIAKSALTQARQRLGQAPLAQLFA..........
F9T0N1_9VIBR/17-109                  ......td--KLGQLSDILCPNFINQCLEATGVATVRK.RRIPLDMAVWTVIAMSLYRQE..PVWSIVSKAQLMLPGK.............K--PLVAPSAVVQARQRLGADAVKEVFH..........
G4FUV5_9GAMM/25-118                  .......p-AAFDRFSQLIPAAWIEQALQATGTTSLRR.RRLPAERLIWLVIGLALFRNE..PIWHIVRQLGLALGTE.............AQ-VVPVPSATVQGRQRLGEAPLAHLFD..........
A0A0A6ZTU1_SHIDY/55-147              ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
Q8E9X7_SHEON/15-107                  ......lt--EFTCLADVLEPELIQSCLDSQGVATLRR.RKLPMDAMIWAVIGMALFRGE..SVRSLINKLDIVLPQE.............I--DYVARSAVTQARKRLGSEVVREVF-s.........
Q7MJC7_VIBVY/18-112                  ......va--QLTTFSEHIPDEWVAKAATLSDKATIRR.RRLPSDMVLWLIVGMAFFRNE..SIAEVARRMNVCAEGL.............ADEELLAKSALTQARQRLGKAAPEWLFR..........
W6R332_9RHIZ/8-101                   .......s-AELSALSQAIDPDWIAQALATTGKASVRK.RKLPAEQVVWLVIALALYRHQ..SIPEVVAHLDLVLPDE.............VN-ADIAKSALTQARQRLGQAPLAQLFA..........
E0SL40_DICD3/21-114                  .......p-ASLSCFQRAIPLEWISQVLDTTQKASIRK.RKFPAERVVWLVVGMGLYRDR..SITDVASKLDLVLSPH.............E-GDTLAASSIAQARQRLSDDPLRELFT..........
W6RG65_9RHIZ/20-113                  .......s-AELSALSQAIDPDWIAQALATTGKASVRK.RKLPAEQVVWLVIALALYRHQ..SIPEVVAHLDLVLPDE.............VN-ADIAKSALTQARQRLGQAPLAQLFA..........
H6RVQ3_BLASD/11-104                  .......p-GHLGELTQIVPFEMVDAVLAKTGTVQQRV.RDLPSRVVVYLLLSAVLFAEC..GYRQVWDRMTAALDGL.............-PVPAPTPAALAAARRRIGAAPLRALFD..........
Q5GZ11_XANOR/1-83                    .......m-------------EWISSALQLSANARIRR.RRLPSDQVLWLVVGMALFRDE..PIHEVARRLNICAQGL.............ASEDLLAKSGVSQARRRLGADPVEALF-s.........
G2P482_STRVO/1-80                    ........--------------MVDEALRAARAVQSRL.RDLPSRVVIYLILAACLFPEV..GYPGVWRKLTGALAGL.............-PVAAPTASALAQARRRVGSKPLRWLFD..........
K9U088_9CYAN/19-113                  ..qslglp------FQELLPESEIQRIIEELQ-IKYRR.RLFDPFVTLWAFLSQVLDVDK..SCHNAVSRIIAYLVNE............kVELPSTDTSAYCQARSRLPEELLQKLF-g.........
K0JV09_SACES/22-123                  ........RVSLGVLAEVVSRDLIEEVLDETGKREQRT.RLLPAHVMVRFCQAMCLFFDD..DYEEVMRKLVGSLKSLksm......gswrGEWHVPSTSAVAQARQRLGSEPLRVLFE..........
A0A0A6ZVQ7_SHIDY/37-129              ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
Q8FLI0_COREF/1-91                    .......m----------FPADVVDEVVAQAGRTQQRS.RILPSRVMVYYTITMALNSDG..SYEDIYADLTDGLSWAcr........weeQAVPAPSRSAIFQARVRLGHEPMAALFA..........
Q32GW6_SHIDS/23-115                  ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............C--PFVAPSAVIQARQRLGSEAVRRVFT..........
B2JV26_BURP8/15-108                  .......p-ADLSRLAEHLPYEWIERAVQATGAASIRR.RRLPAEQVVWLVIALAMYRHW..SISEVLDSLDLALPNE.............A-APFVSKSAVVQARQRIGEAPMAWLFE..........
W6RRJ7_9RHIZ/20-113                  .......s-AELSALSQAIDPDWIAQALATTGKASIRK.RKLPAEQVVWLVIALALYRHQ..SIPEVVAHLDLVLPDE.............VN-ADIAKSALTQARQRLGQAPLAQLFA..........
A8L021_FRASN/17-115                  .......r-IGIGVLTRLVDRDLVDEVLADTGKREQRT.RLLPARVVVYYVMALCLFFEE..SYEEVMRILVDGLRSLgs.........wsKDWHVPTTSAISKARTRLGPEPLQVLFE..........
D2TQC4_CITRI/18-112                  ....ppsa----QLFAQHLPVEWIQHCLTLSAHATVRR.RRLPGDMVIWMVVAMAFFRNE..SITDVVRRLNLSADGE.............AGMNLLARSAVTQARQRVGAAPVEWLFR..........
A0A0A7A560_SHIDY/17-109              ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
K0JWE3_SACES/22-120                  ........RVSLGVLAEVVSRDLIEEVLDETGKREQRT.RLLPAHVMVRFCQAMCLFFDD..DYEEVMRKLVGSLKSMgs.........wrGEWHVPSTSAVAQARQRLGSEPLRVLFE..........
F5XSB1_MICPN/11-91                   .rqtggsp-------------------------QEVRY.RRLPARLMMVFTLACWLFMRS..GYGLVLSRLADAQALTgg.........gwGDWQAPGTGSITKAKAKLGAEPFKLLFA..........
Q32FF6_SHIDS/23-115                  ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMALERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
W6R5G7_9RHIZ/20-113                  .......s-AELSALSQAIDPDWIAQALATTGKASIRK.RKLPAEQVVWLVIALALYRHQ..SIPEVVAHLDLVLPDE.............VN-ADIAKSALTQARQRLGQAPLAQLFA..........
K9ZE46_ANACC/15-108                  ...svglp------FAELLPESVINESIQELNL-KYHQ.RIFSPVVRIWAFLSQVLDVDK..SCQNIVSRVIAWLSTT............gAELPSTNTSAYCQARERLPEKLLSKLF-s.........
A0A089PQ08_PLUGE/15-107              .......p-KEFSALSDLLSPELINECLVDTGVATIRK.RRLPMEMMVWAVTGMTLFRSL..SMNQLVSHLDILLPGK.............R--PFVAPSAVVQARQRLGADVIRSVFE..........
Q8CM19_SHEON/15-107                  ......lt--EFTCLADVLEPELIQSCLDSQGVATLRR.RKLPMDAMIWAVIGMALFRGE..SVRSLINKLDIVLPQE.............I--DYVARSAVTQARKRLGSEVVREVF-s.........
F5XT14_MICPN/18-116                  ........RVSIGVLARSFPAAVLDEVIEAAGVREVRY.RRLPARLMMVFTLACWLFMRS..GYGLVLSRLADAQALTgg.........gwGDWQAPGTGSITKAKAKLGAEPFKLLFA..........
Q5QU56_IDILO/15-107                  .......p-DDFSKLPDLLEPELIEQCLEDAGVTTVRK.RRLPMDFMVWAVVGMALFREM..PMRQLVSHLDLMLPGK.............R--PYVAPSAVVQARQRLGANVMKRMFE..........
G8MC69_9BURK/15-108                  ....padp----SRLAEHLPYEWIERAVQATGVASIRR.RRLPAEQVVWLVIALAMYRHW..SISEVLDNLDLALPDN.............A-APFVSKSAVAQARQRIGEAPLAWLFE..........
F8B083_FRADG/12-110                  .......r-ISIGVLARIVPRDLVEEVLVETKRQERRT.RLLPARVMVYFTMTMCLFFDD..DYEEVMRKLAGALRWLgn.........wqGDWKVPTTGAISQARIRLGAAPLKVLFE..........
Q7MLW1_VIBVY/18-112                  ......va--QLTTFSEHIPDEWVAKAATLSDKATIRR.RRLPSDMVLWLIVGMAFFRNE..SIAEVARRMNVCAEGL.............ADEELLAKSALTQARQRLGKAAPEWLFR..........
D7C169_STRBB/10-102                  .......p-GHLGELTQVVPPELIDAVLEETGARERRL.RCLPSRVGVYFVLALGLFEHL..GARLVWTKLAAGLTAR.............V--PEPSEKALRDLRRRIGPAPVKRLFE..........
D2ASB5_STRRD/13-111                  ......ql--SIGFLTSVFPISLLDEVIGVSGCAERRR.RALPARLTIYYVLALCLFSDK..NYDQVMRLLLNGLAWRsr.........wvYTWEPPSASAISRARARLGAEPLRVLF-c.........
D2TIW6_CITRI/18-112                  ....ppsa----QLFAQHLPVEWIQHCLTLSAHATVRR.RRLPGDMVIWMVVAMAFFRNE..SITDVVRRLNLSADGE.............AGMNLLARSAVTQARQRVGAAPVEWLFR..........
C1DHR3_AZOVD/11-104                  .......s--DLSTFTRNIPVEWVASALNLSAQATIRR.RRLPSDQVLWLVLGMALFRDE..PVHEVARRLNICAQGL.............ASDQLLARSGVTEARKRLGADPVESLFR..........
Q326Z2_SHIDS/23-115                  ......rn--PLTSLGDYLAPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
Q1LFQ5_RALME/20-118                  ......li--SAGVLASVCPRTLIEEVLAETGKASQRE.RLLPAPAVVYYVMALALWREA..PLEEVLRVVCEGLQWLgg.........ghTEAVQASKSAISQARSRLGPEVMRQL--ad........
A8L643_FRASN/1-68                    .......m------------------------------.--LPARLVVYFTLAMCLFFDD..DYEEVLRRLVSSTLWRgn.........rdAGWQVATSGAASQARRPLGPEPLAELFR..........
A4JGL4_BURVG/20-118                  ......li--SAGVLASVCPRTLIEEVLAETGKASQRE.RLLPAPAVVYYVMALALWREA..PLEEVLRVVCEGLQWLgg.........ghTEAVQASKSAISQARSRLGPEVMRQL--ad........
Q8FPL6_COREF/18-117                  ......li--SVGLLTRVFPADVVDEVVAQAGRTQQRS.RILPSRVMVYYTITMALNSDG..SYEDIYADLTDGLSWAcr........weeQAVPAPSRSAIFQARVRLGHEPMAALFA..........
G8MQD6_9BURK/1-91                    ......mr-----RLAEHLPDEWIKRAVQATGTASIRR.RRLPAEQVVWLVIALAMYRHL..SISEVLDSLDPALPDE.............L-APFVSKSAVAQASQRVGEAPMAWLFE..........
Q8FRV1_COREF/18-117                  ......li--SVGLLTRVFPADVVDEVVAQAGRTQQRS.RILPSRVMVYYTITMALNPDG..SYEDIYADLTDGLSWAcr........weeQAVPAPSRSAIFQARVRLGHEPMAALFA..........
A0A089PKE2_PLUGE/15-107              .......p-KEFSALSDLLSPELINECLVDTGVATIRK.RRLPMEMMVWAVTGMTLFRSL..SMNQLVSHLDILLPGK.............R--PFVAPSAVVQARQRLGADVIRSVFE..........
B2JAP6_NOSP7/5-99                    ....kdll----KAIETAIPATAIEQAIATSEANEARN.RSLPAHLVVCLVVAMSLWSRD..SMRDVLKNLVDGLSVGwv........kvgKYWRVPVRVLMFQ---------------aattariati
V6KH62_STRNV/4-99                    .......r-IAIGVLTQAFPPGLVDEVIAETGRAEQRS.RLLPARVVVYFILAMCLFFGQ..GYEEVARLLGEGLGDG............rRSWRVPTTAAIGRARRRLGVEPLKALFA..........
A0A0A6ZYA8_SHIDY/23-115              ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
F8B6B6_FRADG/21-119                  .......r-ISIGVLARIVPRDLVEEVLVETKRQERRT.RLLPARVMVYFTMTMCLFFDD..DYEEVMRKLAGALRWLgn.........wqGDWKVPTTGAISQARIRLGAAPLKVLFE..........
Q32JF1_SHIDS/23-115                  ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQLLGSEAVRRVFT..........
A0A0D5EHH2_9BURK/17-116              ......li--SAGVLAAACPRPLIEAILAETGKASQRE.RRLPAPAVVYYVMALALWREA..PLEEVLRVVCEGLQWLgg........adqTEAVQVSKSAISQARTRLGPDVMRHL--aq........
D4ZJM3_SHEVD/15-107                  .......p-HQVETLADLLPLELIEEAYSLTDTVTIRK.RKLTLESMAWLLIGMAIYNDK..SMAHIVNMLDIVDREG.............K--PFVAPSALTQRRKDLGEAAMKALFE..........
Q7ML52_VIBVY/18-112                  ......va--QLTTFSEHIPDEWVAKAATLSDKATIRR.RRLPSDMVLWLIVGMAFFRNE..SIAEVARRMNVCAEGL.............ADEELLAKSALTQARQRLGKAAPEWLFR..........
INSG_ECOLI/17-109                    ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMALERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
Q6D540_PECAS/17-109                  .......r-NPLSTLAEVLDPELVARCLEEAGTVTLRK.RRLTTDMMVWCLIGIALERKE..PLHQIVNRLDILPPGN.............R--PFVAPSAVVQARQRLGSEAVRLVFE..........
F8AZF0_FRADG/12-110                  .......r-ISIGVLARIVPRDLVEEVLVETKRQERRT.RLLPARVMVYFTMTMCLFFDD..DYEEVMRKLAGALRWLgn.........wqGDWKVPTTGAISQARIRLGAAPLKVLFE..........
A0A0A7A128_SHIDY/17-109              ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
A8LF21_FRASN/21-119                  .......r-ISLGVLARIVPRDLVDEVLAETRRLEQRK.RLLPARVVVYFTMAMCLFFDD..DYDEVMRRLVGTLRWLgs.........wkGDWKVPSTGAISQARTRLGPEPLKLLFE..........
A0A077LNH5_9PSED/17-118              ......li--SAGVLINSCPRTLIDEVLKQTGRGSQRE.RLLTAPTVVYYVMAMALWRDA..PLEEVLRIVCEGANWLniga.....gahpHNLQLPTKSAISAARNRLGAKVMQGL--a.........
G2NZZ3_STRVO/10-103                  .......h-VRLGVVTRWVTPELVAGVLEKCGVRDKKP.GALPAGFMVYFTLALALFQQD..SHDDVAEQLVGAIREL.............S-GRIPNKSSFTRARKRLGPLVLETVFR..........
E4N371_KITSK/18-116                  .......r-IALGVLTRAYPPELIDEVVAACGRTEQRS.RLLPARVVVYFVLAMCLFFGQ..GYEEVARLLVQGLEREsr.........waNGWRVPTTAAIGRARLRLGPEPLRALFA..........
G0HGE0_CORVD/1-55                    ........------------------------------.--------------MALNPQG..SYADVLDQLTDGLSWAsg.........wqDIYQPPSPAAVVQARRRLGSSPLRLLFD..........
G0G104_AMYMS/14-107                  .......p-GHLGELTQIVPFEMVDAALAETRRMQQRL.RVLPSRVVVYLLLAAGLFTEV..GLSQVWTRLCAGLDKL.............A-VARPSPSALAAARVRVGAVPLRALFD..........
C6WCS4_ACTMD/18-116                  .......r-IAIGLLTRSFPPELVDRVIAETGREGQRD.RLLPPRVVVYFVLAMCLFSGQ..GYEEVARLLTEGLSWAar.........wsKPWRVPTTAAISRARVKLGAAPLKALFE..........
Q32J58_SHIDS/23-115                  ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............C--PFVAPSAVIQARQRLGSEAVRRVFT..........
A0A0A7A4L6_SHIDY/23-96               .......r-NPLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGT.............E---------------------------tltcfr....
D0LI35_HALO1/16-109                  .......p-EEFSRLARDVAPEWIEQALEATGTATLRR.RRLPMEQLVWLVIGMALFRDR..PITEVVTSLDLALPSP.............G-HPEVAPSAVAQARDRLGESPMAWLFA..........
Q7MGY3_VIBVY/17-109                  .......t-EQLGKLSDILCPDFINQCLDASGVATIRK.RRIPLDMAVWAVVAMSLYRQE..PLWSIVSKAQLMLPGK.............R--SLVAPSAIVQARQRLGADAMKEVFH..........
Q2JAY9_FRASC/18-127                  ........RVTVGVLTRVYPPELVDRVLAVTDTAEVRR.RLLPSWLVVYFVLALWLFRGRncGYVQVLARLTSGLHFQrraavlaaggaggAGWSLPASPSLGEARARIGSDPVRMLFE..........
M4NBA0_9GAMM/25-118                  ......pd--AFDRFSQLIPAAWIEQALQATGTTSLRR.RRLPAERLIWLVIGLALFRNE..PIWHIVRQLGLALGTE.............AQ-VVPVPSATVQGRQRLGEAPLAHLFD..........
E1VVQ6_ARTAR/18-116                  .......h-VSLGVLAKVFPPSLVNEVVTKVGAGEQRS.RLLPAWMMVYYVMALALHAAA..SYEEVMRNLLGGLQWIsh.........rtSEWSMPTKAAIFKARTRLGAPVMIELFD..........
Q82R31_STRAW/23-116                  .......p-GHLGELTQQLPFELVDDVLERAGGAQHRL.RLLPSRVGVYFVLALALFPQL..GYVRVWDKLTAGLRGI.............L-HRRPSEKALREVRRRLGVAPLRLLFE..........
E0SFQ3_DICD3/15-107                  .......p-EHACSLSDLIPIELIHQAFTLTDTVTLRK.RKLPLESMIWLVVGMSIFCNR..PMTEIVNLMDITDRTG.............A--PFTARSSVIQRRKTLGEDAVRELFD..........
A0A0A7A2Y2_SHIDY/23-115              ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
D2TNL1_CITRI/15-108                  .......p-ASLSCFQRAIPLEWISQVLDSTNKASIRK.RKLPAELVVWLIVGMGLYRDR..SITDVVTKLDLVLSSQ.............E-GETLAASSVARARQRLSDEPLRELFT..........
Q32E26_SHIDS/23-115                  ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMALERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
F8AYX9_FRADG/12-92                   .......r-ISIGVLARIVPRDLVEEVLVETKRQERRT.RLLPARVMVYFTMTMCLFFDD..DYEEVMRKLAGALRWL.............GNWQ------------------------gdwespdhrg
Q82QY0_STRAW/23-116                  .......p-GHLGELTQQLPFELVDDVLERAGGAQHRL.RLLPSRVGVYFVLALALFPQL..GYVRVWDKLTAGLRGI.............L-HRRPSEKALREVRRRLGVAPLRLLFE..........
Q32CZ3_SHIDS/23-115                  ......rn--PLTSLGDYLAPELISRCLAESGTVTLRK.RRLPLEMMVWCIVGMVLERKE..PLHQIVNRLDIMLPGN.............R--PFVAPSAVIQARQRLGSEAVRRVFT..........
A0A0A7A0P6_SHIDY/23-115              ......rn--PLTSLGDYLDPELISRCLAESGTVTLRK.RRLPLEMMVWCTVGMVLERKE..PLHQIVNRLDIMLPAI.............R--PSFAPVAVIQARQRLGSEAVRRVFT..........
W6R4D8_9RHIZ/20-113                  .......s-AELSALSQAIDPDWIAQALATTGKASIRK.RKLPAEQVVWLVIALALYRHQ..SIPEVVAHLDLVLPDE.............VN-ADIAKSALTQARQRLGQAPLAQLFA..........
#=GC seq_cons                        ..........tlssLuchls.-hlscsLspoGpsshR+.RcLPschhVahlluMsLapcp..shppVhs+LshsLsst.............t..shsutSAlsQARpRLGstslctLFp..........
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