GenomeNet

Database: Pfam
Entry: Nup_retrotrp_bd
LinkDB: Nup_retrotrp_bd
Original site: Nup_retrotrp_bd 
#=GF ID   Nup_retrotrp_bd
#=GF AC   PF10599.5
#=GF DE   Retro-transposon transporting motif  
#=GF AU   Wood V, Coggill P
#=GF SE   Wood V
#=GF GA   25.00 25.00;
#=GF TC   25.20 25.20;
#=GF NC   24.70 24.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   17615301
#=GF RT   Multiple conserved domains of the nucleoporin Nup124p and its
#=GF RT   orthologs Nup1p and Nup153 are critical for nuclear import and
#=GF RT   activity of the fission yeast Tf1 retrotransposon. 
#=GF RA   Sistla S, Pang JV, Wang CX, Balasundaram D; 
#=GF RL   Mol Biol Cell. 2007;18:3692-3708.
#=GF DR   INTERPRO; IPR018892;
#=GF CC   This is the highly conserved C-terminal motif GRKIxxxxxRRKx of
#=GF CC   nucleoporins that plays a critical and unique role in the
#=GF CC   nuclear import of retro-transposons in both yeasts and higher
#=GF CC   organisms. It would appear that the arginine residues at
#=GF CC   positions 2 and 9-10 constitute a bipartite nuclear localisation
#=GF CC   signal, with two basic peptide motifs separated by an
#=GF CC   interchangeable spacer sequence, that is crucial for the
#=GF CC   retro-transposon activity [1].
#=GF SQ   89
#=GS S9XPJ2_9CETA/2720-2811      AC S9XPJ2.1
#=GS E9Q3G8_MOUSE/1372-1462      AC E9Q3G8.1
#=GS I3M6R8_SPETR/1379-1469      AC I3M6R8.1
#=GS E7Q9M2_YEASB/934-1038       AC E7Q9M2.1
#=GS G1L1N5_AILME/1384-1476      AC G1L1N5.1
#=GS U3IHS3_ANAPL/69-156         AC U3IHS3.1
#=GS H9G2P1_MACMU/1385-1474      AC H9G2P1.1
#=GS U3B4E1_CALJA/1380-1470      AC U3B4E1.1
#=GS I0FWW1_MACMU/1384-1474      AC I0FWW1.1
#=GS E7M0B3_YEASV/934-1076       AC E7M0B3.1
#=GS Q80WR0_MOUSE/1372-1462      AC Q80WR0.1
#=GS A0A024QZW7_HUMAN/1385-1475  AC A0A024QZW7.1
#=GS H2PI06_PONAB/1349-1439      AC H2PI06.1
#=GS H0Z6B1_TAEGU/1332-1419      AC H0Z6B1.1
#=GS Q80UN3_MOUSE/838-928        AC Q80UN3.1
#=GS L8YAU1_TUPCH/857-920        AC L8YAU1.1
#=GS G2HFE7_PANTR/440-530        AC G2HFE7.1
#=GS H2R1J5_PANTR/1416-1506      AC H2R1J5.1
#=GS W5PPG7_SHEEP/1375-1467      AC W5PPG7.1
#=GS F7BCM6_MONDO/1366-1456      AC F7BCM6.2
#=GS C7GMN6_YEAS2/934-1076       AC C7GMN6.1
#=GS G2WMX5_YEASK/934-1076       AC G2WMX5.1
#=GS NU153_RAT/1378-1468         AC P49791.1
#=GS U3DFY6_CALJA/1380-1470      AC U3DFY6.1
#=GS H0V265_CAVPO/1381-1472      AC H0V265.1
#=GS E2RLN2_CANFA/1387-1478      AC E2RLN2.2
#=GS G1SIZ4_RABIT/1382-1473      AC G1SIZ4.2
#=GS S7N4Q5_MYOBR/1382-1473      AC S7N4Q5.1
#=GS F7EI13_CALJA/947-1036       AC F7EI13.1
#=GS U6DDK8_NEOVI/1266-1357      AC U6DDK8.1
#=GS G3GUG1_CRIGR/1235-1326      AC G3GUG1.1
#=GS U3EWG3_CALJA/1380-1470      AC U3EWG3.1
#=GS U3KG17_FICAL/1304-1390      AC U3KG17.1
#=GS B5VRZ2_YEAS6/934-1076       AC B5VRZ2.1
#=GS K9K9V1_HORSE/238-329        AC K9K9V1.1
#=GS G3U2A5_LOXAF/1382-1472      AC G3U2A5.1
#=GS A6ZNU8_YEAS7/939-1081       AC A6ZNU8.1
#=GS G1MW17_MELGA/1335-1422      AC G1MW17.1
#=GS F7EUV5_ORNAN/1377-1466      AC F7EUV5.2
#=GS A0A023ZH59_YEASX/939-1081   AC A0A023ZH59.1
#=GS K7GGR9_PELSI/1339-1427      AC K7GGR9.1
#=GS D2HWA0_AILME/1347-1440      AC D2HWA0.1
#=GS L5LVD6_MYODS/1157-1248      AC L5LVD6.1
#=GS G7P4H7_MACFA/1369-1459      AC G7P4H7.1
#=GS Q5XFX2_RAT/485-575          AC Q5XFX2.1
#=GS F7DUR1_HORSE/1375-1465      AC F7DUR1.1
#=GS G1KCK7_ANOCA/1343-1427      AC G1KCK7.1
#=GS G3V662_RAT/1378-1468        AC G3V662.1
#=GS A0A024XWJ6_YEASX/934-1076   AC A0A024XWJ6.1
#=GS G1QKG7_NOMLE/1386-1475      AC G1QKG7.1
#=GS J9JHY9_CANFA/1367-1458      AC J9JHY9.1
#=GS W7QUZ5_YEASX/934-1076       AC W7QUZ5.1
#=GS A0A024XIE5_YEASX/934-1076   AC A0A024XIE5.1
#=GS F1NWC8_CHICK/1324-1411      AC F1NWC8.2
#=GS H0XC65_OTOGA/1415-1507      AC H0XC65.1
#=GS J3SCU1_CROAD/1366-1450      AC J3SCU1.1
#=GS W7P9Q4_YEASX/934-1076       AC W7P9Q4.1
#=GS I3LEL0_PIG/1387-1477        AC I3LEL0.1
#=GS K7C6M5_PANTR/1385-1475      AC K7C6M5.1
#=GS NU124_SCHPO/1072-1159       AC Q09904.1
#=GS G3RSS3_GORGO/1386-1476      AC G3RSS3.1
#=GS F7EHG8_CALJA/1381-1470      AC F7EHG8.1
#=GS Q8R2M9_MOUSE/374-464        AC Q8R2M9.1
#=GS F6V9A5_MACMU/1343-1432      AC F6V9A5.1
#=GS G1P376_MYOLU/1421-1511      AC G1P376.1
#=GS NUP1_YEAST/934-1076         AC P20676.1
#=GS NUP1_YEAST/934-1076         DR PDB; 2BPT B; 974-1012;
#=GS E1BIX5_BOVIN/1393-1485      AC E1BIX5.2
#=GS L5KU23_PTEAL/1383-1469      AC L5KU23.1
#=GS J9NV51_CANFA/1251-1342      AC J9NV51.1
#=GS NU153_HUMAN/1385-1475       AC P49790.2
#=GS NU153_HUMAN/1385-1475       DR PDB; 4U0D Q; 1410-1418;
#=GS NU153_HUMAN/1385-1475       DR PDB; 4U0D R; 1410-1418;
#=GS NU153_HUMAN/1385-1475       DR PDB; 4U0D N; 1410-1418;
#=GS NU153_HUMAN/1385-1475       DR PDB; 4U0C B; 1410-1418;
#=GS NU153_HUMAN/1385-1475       DR PDB; 4U0D O; 1410-1418;
#=GS NU153_HUMAN/1385-1475       DR PDB; 4U0D M; 1410-1418;
#=GS NU153_HUMAN/1385-1475       DR PDB; 4U0D P; 1410-1418;
#=GS B3LJE4_YEAS1/934-1076       AC B3LJE4.1
#=GS Q6BZ26_DEBHA/940-1045       AC Q6BZ26.2
#=GS Q3TA10_MOUSE/1-42           AC Q3TA10.1
#=GS M3WFC8_FELCA/1398-1488      AC M3WFC8.1
#=GS I7GJD0_MACFA/311-400        AC I7GJD0.1
#=GS H9ZG48_MACMU/1384-1474      AC H9ZG48.1
#=GS A5DA71_PICGU/906-969        AC A5DA71.2
#=GS C8ZI59_YEAS8/934-1076       AC C8ZI59.1
#=GS F6V9C1_MACMU/1385-1474      AC F6V9C1.1
#=GS L8IHP7_9CETA/1382-1474      AC L8IHP7.1
#=GS K9J0M1_DESRO/1386-1476      AC K9J0M1.1
#=GS A3LRH6_PICST/919-1019       AC A3LRH6.2
#=GS Q8BRF6_MOUSE/576-666        AC Q8BRF6.1
#=GS H0GNL9_SACCK/934-1076       AC H0GNL9.1
#=GS Q3V3W1_MOUSE/407-497        AC Q3V3W1.1
#=GS N1P335_YEASC/934-1076       AC N1P335.1
#=GS G3RED7_GORGO/1415-1506      AC G3RED7.1
#=GS G3TFY7_LOXAF/1392-1482      AC G3TFY7.1
#=GS G5AXT4_HETGA/1413-1504      AC G5AXT4.1
S9XPJ2_9CETA/2720-2811                 ..gsg--TAPNSSSAFQF.GSS.TTSFNF--------TNNNPS....GVFTFGANPSTP--...................--AASAQPSGSGGFP....FNPS..........PAV----FTVGSNGKNVFSSSg.tSVSGRKIKTAVRRKK.........
E9Q3G8_MOUSE/1372-1462                 ....g-SGTANASSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGASPSTP--...................--AASAQPSGSGVFS....FSQS..........PAS----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRKK.........
I3M6R8_SPETR/1379-1469                 ...sg--AAPNPSSGFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANPSTP--...................--AASAQPSGSGGFP....FNQP..........TAA----FTVGSNGKNMFSSSg.tSVPARKIKTAVRRKK.........
E7Q9M2_YEASB/934-1038                  .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTXSfntnSSFTPSTVPNINFSglnggitntatnxlrpsdiFGANAASGSNSNVTNpssiFGG-..........---------------------...---------------grwcadnff
G1L1N5_AILME/1384-1476                 ...sa--AAPSSGSVFQF.GGS.SSTTNF------NFTNNNPS....GVFTFSANPSTP--...................--AASAQPSGSGGFP....FNQP..........SAA----FTVGSNGKNVFSSSg.tSVSGRKIKTAVRRRK.........
U3IHS3_ANAPL/69-156                    ....g-SGTSSAGPVFQF.GSN.TSNFNF----------PNNP....GVFTFGANPTAP--...................--TASAQPSGSSGFS....FSQP..........PAF-----TVGTNGKNIFSASg.sSVSGRKIKTAFRRRK.........
H9G2P1_MACMU/1385-1474                 ....s-GTTPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNQS..........PAA----FTVGSNGKNVFSSG..tSVSGRKIKTAVRRRK.........
U3B4E1_CALJA/1380-1470                 ...gs-GTTANSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNPS..........PAF-----TVGSNGKNVFSSSg.tAVPGRKIKTAVRRRK.........
I0FWW1_MACMU/1384-1474                 ...gs-GTTPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNQS..........PAA----FTVGSNGKNVFSSG..tSVSGRKIKTAVRRRK.........
E7M0B3_YEASV/934-1076                  .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTPSfntnSSFTPSTVPNINFSglnggitntatntlrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
Q80WR0_MOUSE/1372-1462                 ....g-SGTANASSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGASPSTP--...................--AASAQPSGSGVFS....FSQS..........PAS----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRKK.........
A0A024QZW7_HUMAN/1385-1475             ....s-GTTPNSSSAFQF.GSS.TTNFNF--------TNNSPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNQS..........PAA----FTVGSNGKNVFSSSg.tSFSGRKIKTAVRRRK.........
H2PI06_PONAB/1349-1439                 ...gs-GTTPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNQS..........PAA----FTVGSNGKSVFSSG..tSGSGRKIKTAVRRRK.........
H0Z6B1_TAEGU/1332-1419                 ....g-SGTPSAGSVFQF.GSN.ATNFSF----------PNNP....GVFTFGA----NPP...................ASAAPAPPSGTLGFS....FNQP..........PTF-----TVGTNGKNVFSASg.sSVPGRKIKTAIRRRK.........
Q80UN3_MOUSE/838-928                   ....g-SGTANASSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGASPSTP--...................--AASAQPSGSGVFS....FSQS..........PAS----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRKK.........
L8YAU1_TUPCH/857-920                   ...sg--AAPNTGSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANPSTP--...................--AACVQPSGSGGFP....FNQA..........PPA----FT------------...---------------vg.......
G2HFE7_PANTR/440-530                   ....s-GTTPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGAFP....FNQS..........PAA----FTVGSNGKNVFSSSg.tSFSGRKIKTAVRRRK.........
H2R1J5_PANTR/1416-1506                 ....s-GTTPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGAFP....FNQS..........PAA----FTVGSNGKNVFSSSg.tSFSGRKIKTAVRRRK.........
W5PPG7_SHEEP/1375-1467                 ..gsg--TAPNSSSIFQF.GSS.TA-TNF------NFTNNNPS....GVFTFGASPSTP--...................--AASAQPSGSGGFQ....FSQA..........SAA----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRKK.........
F7BCM6_MONDO/1366-1456                 ....s-GTTPNSSSVFHF.GSS.TANFNF--------TNNNPS....GVFTFGANAGTP--...................--AASAQPSGSAVFP....FNPS..........PAA----FTVGTNGKNMFSASg.tSVSGRKIKTAVRRRK.........
C7GMN6_YEAS2/934-1076                  .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTPSfntnSSFTPSTVPNINFSglnggitntatntlrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
G2WMX5_YEASK/934-1076                  .....NNSTPGGGSLFNMnGNT.NANTVFAGSNNQPHQSQTSSfntnSSFTPSTVPNINFSglnggitntatnalrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
NU153_RAT/1378-1468                    ....g-SGTANASSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGASPSTP--...................--AAAAQPSGSGGFS....FSQS..........PAS----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRKK.........
U3DFY6_CALJA/1380-1470                 ...gs-GTTANSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNPS..........PAF-----TVGSNGKNVFSSSg.tAVPGRKIKTAVRRRK.........
H0V265_CAVPO/1381-1472                 ....s-GTTPNSSSVFQF.GSSsTTNFNF--------TNNNPS....GVFTFGANPSTP--...................--AASAQPSGSGNFP....FSQS..........AAA----FTVGSNGKNMFSSPg.tSVPGRKIKTAVRRKK.........
E2RLN2_CANFA/1387-1478                 .gsat---APSSGSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANPSTP--...................--AASAQPSGSGGFP....FSQS..........SPA----FTMGSNGKNMFSSSg.tSVSGRKIKTAVRRRK.........
G1SIZ4_RABIT/1382-1473                 ..gsg--TAPNSNSVFQF.GSS.TANFNF--------TSNNPA....GVFTFGANFSTP--...................--AASTQPSGSGSFP....FNPS..........Q----ATFTVGSNGKSMFSSSg.tSVSGRKIKTAVRRKK.........
S7N4Q5_MYOBR/1382-1473                 ..gsg--TAPNSGSVFQF.GSS.TTNFNF--------TNNSTS....GVFKFGANPSTP--...................--AAPAQPSGSGAFP....FNQP..........SAS----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRRK.........
F7EI13_CALJA/947-1036                  ....s-GTTANSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNPS..........PAF-----TVGSNGKNVFSSSg.tAVPGRKIKTAVRRRK.........
U6DDK8_NEOVI/1266-1357                 aaaps-----SGSSVFQF.GSSsTTNFNF--------ANNNPS....GVFTFGANPGTP--...................--AASAQPSGSAAFA....FSQS..........SAA----FTVGSNGKNMFSSSg.tSVPGRKIKTAVRRRK.........
G3GUG1_CRIGR/1235-1326                 ..gsg--TAPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANPSTP--...................--AASAQPSGSGGFQ....FSQS..........PAS----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRRK.........
U3EWG3_CALJA/1380-1470                 ...gs-GTTANSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNPS..........PAF-----TVGSNGKNVFSSSg.tAVPGRKIKTAVRRRK.........
U3KG17_FICAL/1304-1390                 ....g-SGTPGAGSVFQF.GSS.TTNFSF---------T-NNP....GVFTFGASPSAA--...................--AAPAPPSGTAGFS....FNQ-..........PT-----FTVGTNGKNVFSASg.sSVPGRKIKTAVRRRK.........
B5VRZ2_YEAS6/934-1076                  .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTPSfntnSSFTPSTVPNINFSglnggitntatntlrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
K9K9V1_HORSE/238-329                   ..gsg--TAPNSSPAFQF.GST.TTNFNF--------TNNNPP....GVFTFGANPSTP--...................--AASAQPSGSGGFP....FSQS..........PAA----FTVGSNGKNMFSSSg.tSVPGRKIKTAVRRRK.........
G3U2A5_LOXAF/1382-1472                 ...sg--AAPNSSSGFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANASTP--...................--AASAQPSGSGGFP....FSQ-..........PSA---GFTVGSNGKNVFSSSg.tPVSGRKIKTAVRRRK.........
A6ZNU8_YEAS7/939-1081                  .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTPSfttnSSFTPSTVPNINFSglnggitntatntlrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
G1MW17_MELGA/1335-1422                 ....g-SSTSSAGPVFQF.GSS.TSNFNF--------TSNPE-....-VFTFGANPPAP--...................--AAPVQPSGSSGFS....FSQP..........PTF-----TVGTNGKNIFSASg.sSVSGRKIKTAVRRRK.........
F7EUV5_ORNAN/1377-1466                 .gsap----SGSGGVFQF.GSS.TTNFNF--------TSNNPT....GVFTFGANAAPP--...................--APSAQPSSTAGFP....FGPV..........PAF-----AVGTNGKNVFSASg.sSVSGRKIKTAVRRRK.........
A0A023ZH59_YEASX/939-1081              .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTPSfntnSSFTPSTVPNINFSglnggitntatntlrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
K7GGR9_PELSI/1339-1427                 ...gs-GTTPNSGGVFQF.GSS.S-NFNF--------TSNSP-....GVFTFGGNSGAP--...................--APPTQPSGSSGFS....FNQP..........PTF-----TVGSNGKNIFSASg.sSVSGRKIKTAVRRRK.........
D2HWA0_AILME/1347-1440                 ..gsa--AAPSSGSVFQF.GGS.SSTTNF------NFTNNNPS....GVFTFSANPSTP--...................--AASAQPSGSGGFP....FNQP..........SAA----FTVGSNGKNVFSSSg.tSVSGRKIKTAVRRRK.........
L5LVD6_MYODS/1157-1248                 ..gsg--TAPNSGSVFQF.GSS.TTNFNF--------TNNSPS....GVFKFGANPTTP--...................--AAPAQPSGSGGFP....FNQP..........SAS----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRRK.........
G7P4H7_MACFA/1369-1459                 ...gs-GTTPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNQS..........PAA----FTVGSNGKNVFSSG..tSVSGRKIKTAVRRRK.........
Q5XFX2_RAT/485-575                     ....g-SGTANASSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGASPSTP--...................--AAAAQPSGSGGFS....FSQS..........PAS----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRKK.........
F7DUR1_HORSE/1375-1465                 ...sg--TAPNSSKSFQF.GST.TTNFNF--------TNNNPP....GVFTFGANPSTP--...................--AASAQPSGSGGFP....FSQS..........PAA----FTVGSNGKNMFSSSg.tSVPGRKIKTAVRRRK.........
G1KCK7_ANOCA/1343-1427                 ....t-GTTPNSGPVFQF.GNS.ATSFNF--------TGNSP-....GVFTFGAAPGTS--...................-----AQPAGSSGFS....FNQ-..........PS-----FNLGSSGKNMFSTPg.sAVSGRKIKTAVRRRK.........
G3V662_RAT/1378-1468                   ....g-SGTANASSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGASPSTP--...................--AAAAQPSGSGGFS....FSQS..........PAS----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRKK.........
A0A024XWJ6_YEASX/934-1076              .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTPSfntnSSFTPSTVPNINFSglnggitntatntlrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
G1QKG7_NOMLE/1386-1475                 ....s-GTTPNSSSVFQF.GSS.ATNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNQS..........PAA----FTVGSNGKNVFSSG..tSVSGRKIKTAVRRRK.........
J9JHY9_CANFA/1367-1458                 .gsat---APSSGSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANPSTP--...................--AASAQPSGSGGFP....FSQS..........SPA----FTMGSNGKNMFSSSg.tSVSGRKIKTAVRRRK.........
W7QUZ5_YEASX/934-1076                  .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTPSfntnSSFTPSTVPNINFSglnggitntatntlrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
A0A024XIE5_YEASX/934-1076              .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTPSfntnSSFTPSTVPNINFSglnggitntatntlrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
F1NWC8_CHICK/1324-1411                 ....g-SGTSSTGPVFQF.GSS.TSNFNF--------TSNPE-....-VFTFGANPPAP--...................--AASVQPSGSSGFS....FSQP..........PAF-----TVGTNGKNIFSASg.sSVSVRKIKTAVRRRK.........
H0XC65_OTOGA/1415-1507                 ..gsg--TAPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANPSTP--...................--AASAQPSGSGGFS....FNQS..........PAA----FTLGSNGKNMFSSSgtsVTAGRKIKTAVRRRK.........
J3SCU1_CROAD/1366-1450                 ...sg--TAPGTGQVFQF.GSS.TANFNF---------SSNSP....GIFTFGASSSAP--...................-----AQPTSSSGFA....FTQA..........SS-----FNPGNNGKSTYSMG..sSVTGRKIKTAVRRRK.........
W7P9Q4_YEASX/934-1076                  .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTPSfntnSSFTPSTVPNINFSglnggitntatntlrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
I3LEL0_PIG/1387-1477                   ...sg--TAPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANPSIP--...................--AASAQPSGSGGFP....FNQS..........PGA----FTVGSNGKNIFSSSg.tSLSGRKIKTAVRRRK.........
K7C6M5_PANTR/1385-1475                 ....s-GTTPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGAFP....FNQS..........PAA----FTVGSNGKNVFSSSg.tSFSGRKIKTAVRRRK.........
NU124_SCHPO/1072-1159                  ....a-GNTPNPSGSIN-.-NA.SQAFAFGSGEPSNPASNPPS....TGFSFGA-------...................-----ATPSAFNASA....-SQS..........PAPNGIQFNLGSSNSQTN---...APPGRKIAVPRSRRKr........
G3RSS3_GORGO/1386-1476                 ....s-GTTPNSSSVFQF.GSS.TTNFNF--------TNNNPP....GVFTFGANSSTP--...................--AASAQPSGSGGFS....FNQS..........PAA----FTVGSNGKNVFSSSg.tSFSGRKIKTAVRRRK.........
F7EHG8_CALJA/1381-1470                 ....s-GTTANSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNPS..........PAF-----TVGSNGKNVFSSSg.tAVPGRKIKTAVRRRK.........
Q8R2M9_MOUSE/374-464                   ....g-SGTANASSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGASPSTP--...................--AASAQPSGSGVFS....FSQS..........PAS----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRKK.........
F6V9A5_MACMU/1343-1432                 ....s-GTTPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNQS..........PAA----FTVGSNGKNVFSSG..tSVSGRKIKTAVRRRK.........
G1P376_MYOLU/1421-1511                 ..gsg--TAPNSGSVFQF.GSS.TTNFNF--------TNNSPS....GVFKFGANPSTP--...................--AAPAQPSGSGFPF....-N-Q..........PSA---SFTVGSNGKNMFSSSg.tSVSGRKIKTAVRRRK.........
NUP1_YEAST/934-1076                    .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTPSfntnSSFTPSTVPNINFSglnggitntatnalrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
#=GR NUP1_YEAST/934-1076         SS    .....XXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXX--S----SS------XXXXXXXXX---X--GGGTTT---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXXX.........
E1BIX5_BOVIN/1393-1485                 ..gsg--TAPNPSSVFQF.GSS.TA-TNF------NFTNSSPS....GVFTFGASPSTP--...................--AASSQPSGSGGFQ....FSQS..........SAA----FTVGSNGKNMFSSSg.pSVSGRKIKTAVRRKK.........
L5KU23_PTEAL/1383-1469                 ...sg--TAPNSSSIFQF.ARS.ATNFSF--------TNNNAS....GIFTFGANPSTP--...................--AASAQPSGSGGFP....----..........-SA---AFTLGSNGKNMFSSSg.tSVSGRKIKTAVRRRK.........
J9NV51_CANFA/1251-1342                 .gsat---APSSGSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANPSTP--...................--AASAQPSGSGGFP....FSQS..........SPA----FTMGSNGKNMFSSSg.tSVSGRKIKTAVRRRK.........
NU153_HUMAN/1385-1475                  ....s-GTTPNSSSAFQF.GSS.TTNFNF--------TNNSPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNQS..........PAA----FTVGSNGKNVFSSSg.tSFSGRKIKTAVRRRK.........
#=GR NU153_HUMAN/1385-1475       SS    ....X-XXXXXXXXXXXX.XXX.XXXXXX--------XXX---....-S-S--XXXXXX--...................--XXXXXXXXXXXXX....XXXX..........XXX----XXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXX.........
B3LJE4_YEAS1/934-1076                  .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTPSfntnSSFTPSTVPNINFSglnggitntatntlrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
Q6BZ26_DEBHA/940-1045                  .....KEGTPDPASIFGG.GAN.NMNTSNIQNGVNGLNKSAES....SPFGFNAHQSTPDFkfangiqqpqfnsglpadmNNQSFNSTSGMTPPT....LSTT..........PPI------------------...IKSNRKIAQMRSRRR.........
Q3TA10_MOUSE/1-42                      ....g-------------.---.--------------------....--------------...................------------VFS....FSQS..........PAS----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRKK.........
M3WFC8_FELCA/1398-1488                 ...sa--AAPSSTSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANPSAP--...................--AAAAQPSGSGGFP....FSH-..........PAA---AFTVGSNGKNMFSSSg.tSVSGRKIKTAVRRKK.........
I7GJD0_MACFA/311-400                   ....s-GTTPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNQS..........PAA----FTVGSNGKNVFSSG..tSVSGRKIKTAVRRRK.........
H9ZG48_MACMU/1384-1474                 ...gs-GTTPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNQS..........PAA----FTVGSNGKNVFSSG..tSVSGRKIKTAVRRRK.........
A5DA71_PICGU/906-969                   .....REPTPDPASIFGA.GSS.NT------------RESTPA....APLGFAT-------...................--QNQNPNTSFTPPP....LSGN..........P--------------------...MVRNRKIAQMRSRRR.........
C8ZI59_YEAS8/934-1076                  .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTPSfntnSSFTPSTVPNINFSglnggitntatntlrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
F6V9C1_MACMU/1385-1474                 ....s-GTTPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANSSTP--...................--AASAQPSGSGGFP....FNQS..........PAA----FTVGSNGKNVFSSG..tSVSGRKIKTAVRRRK.........
L8IHP7_9CETA/1382-1474                 ..gsg--TAPNPSSVFQF.GSS.TA-TNF------NFTNSSPS....GVFTFGASPSTP--...................--AASSQPSGSGGFQ....FSQS..........SAA----FTVGSNGKNMFSSSg.pSVSGRKIKTAVRRKK.........
K9J0M1_DESRO/1386-1476                 ..gsg--TAPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANPSTP--...................--AASAQPSGSGGFP....FTQL..........SAS----FTVGSNGKSAFSSG..tSVSGRKIKTAVRRRK.........
A3LRH6_PICST/919-1019                  .....KEATPDPASVFGM.NNS.NAN-----------MGSREA....TPFAFGTGTGVSNP...................ASVFGNPGNAISMPAptagFGGT..........PAFAFGGVNGGAGGSLAPNQTptpPLQGRMIARMRQRRR.........
Q8BRF6_MOUSE/576-666                   ....g-SGTANASSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGASPSTP--...................--AASAQPSGSGVFS....FSQS..........PAS----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRKK.........
H0GNL9_SACCK/934-1076                  .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTPSfntnSSFTPSTVPNINFSglnggitntatntlrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
Q3V3W1_MOUSE/407-497                   ....g-SGTANASSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGASPSTP--...................--AASAQPSGSGVFS....FSQS..........PAS----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRKK.........
N1P335_YEASC/934-1076                  .....NNSTPGGGSVFNMnGNT.NANTVFAGSNNQPHQSQTPSfntnSSFTPSTVPNINFSglnggitntatnalrpsdiFGANAASGSNSNVTNpssiFGGAggvpttsfgqPQSAPNQMGMGTNNGMSMGGG...VMANRKIARMRHSKR.........
G3RED7_GORGO/1415-1506                 ...gs-GTTPNSSSVFQF.GSS.TTNFNF--------TNNNPP....GVFTFGANSSTP--...................--AASAQPSGSGGFS....FNQS..........PAA----FTVGSNGKNVFSSSg.tSFSGRKIKTAVRRRK.........
G3TFY7_LOXAF/1392-1482                 ...sg--AAPNSSSGFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANASTP--...................--AASAQPSGSGGFP....FSQ-..........PSA---GFTVGSNGKNVFSSSg.tPVSGRKIKTAVRRRK.........
G5AXT4_HETGA/1413-1504                 ...gs-GTTPNSSSVFQF.GSS.TTNFNF--------TNNNPS....GVFTFGANPSIP--...................--AASAQPSGSGSFP....FSQS..........SAA----FTVGSNGKNMFSSSg.tSVSGRKIKTAVRRRK.........
#=GC SS_cons                           ....X-XXXXXXXXXXXX.XXX.XXXXXX--------XXX---....-S-S--SSXXXX--...............GGGTTTXXXXXXXXXXXXX....XXXX..........XXX----XXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXX.........
#=GC seq_cons                          ....u.soTPNuuSVFQF.GSS.TTNFNF........TNNNPS....GVFTFGAsPSTP.......................AASAQPSGSGuFs....FsQu..........PAu....FTVGSNGKNhFSSSG.TSVSGRKIKTAVRRRK.........
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