GenomeNet

Database: Pfam
Entry: Orbi_VP6
LinkDB: Orbi_VP6
Original site: Orbi_VP6 
#=GF ID   Orbi_VP6
#=GF AC   PF01516.14
#=GF DE   Orbivirus helicase VP6
#=GF AU   Bateman A
#=GF SE   Pfam-B_765 (release 4.0)
#=GF GA   22.60 22.60;
#=GF TC   22.70 715.90;
#=GF NC   19.60 22.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9311795
#=GF RT   Bluetongue virus VP6 protein binds ATP and exhibits an
#=GF RT   RNA-dependent ATPase function and a helicase activity that
#=GF RT   catalyze the unwinding of double-stranded RNA substrates. 
#=GF RA   Stauber N, Martinez-Costas J, Sutton G, Monastyrskaya K, Roy P; 
#=GF RL   J Virol 1997;71:7220-7226.
#=GF DR   INTERPRO; IPR001399;
#=GF CC   The VP6 protein a minor protein in the core of the virion is
#=GF CC   probably the viral helicase [1].
#=GF SQ   2
#=GS VP6A_BTV10/6-329  AC Q98829.3
#=GS VP6B_BTV10/2-325  AC P33423.1
VP6A_BTV10/6-329             LLAPGDVIKRSSEELKQRQIQINLVDWMESEGGKEDKTEPKEESKAEGSKDGEGTQSESGQKEEGGKETKDADVDRRIHTAVGSGSGTKGSGERANENANRGDGKVGGGGGDADAGVGATGTNGGRWVVLTEEIARAIESKYGTKIDVYRDEVPAQIIEVERSLQKELGISREGVAEQTERLRDLRRKEKNGTHAKAVERGGRKQRKKAHGDAQREGVEEEKTSEEPARIGITIEGVMSQKKLLSMIGGVERKMAPIGARESAVMLVSNSIKDVVRATAYFTAPTGDPHWKEVAREASKKKNILAYTSTGGDVKTEFLHLIDHL
VP6B_BTV10/2-325             LLAPGDVIKRSSEELKQRQIQINLIDWIESESGKEDKAEPKEESKAEESKDGQGTQSESSQKKEGSKEAKDADVDRRIHTAVGSGSSAKGPGVRANENVDRGDGKVGGGGGNADAGVGTIGANGGRWVVLTEEIARAIESKYGTKIDVYRDKVPAQIIEVERSLQKELGISREGVAEQTERLRDLRRKEKSGAHAKAAERGRRKQGKKPHGDVQKEGTEEEKTSEEQASVGIAIEGVMSQKKLLSMIGGVERKMAPIGARESAVMLVSNSIKDVVRATAYFTAPTGDPHWKEVAREASKKKNILAYTSTGGDVKTEFLHLIDHL
#=GC seq_cons                LLAPGDVIKRSSEELKQRQIQINLlDWhESEuGKEDKsEPKEESKAEtSKDGpGTQSESuQKcEGuKEsKDADVDRRIHTAVGSGSusKGsG.RANENssRGDGKVGGGGGsADAGVGshGsNGGRWVVLTEEIARAIESKYGTKIDVYRDcVPAQIIEVERSLQKELGISREGVAEQTERLRDLRRKEKsGsHAKAsERGtRKQtKKsHGDsQ+EGsEEEKTSEE.AplGIsIEGVMSQKKLLSMIGGVERKMAPIGARESAVMLVSNSIKDVVRATAYFTAPTGDPHWKEVAREASKKKNILAYTSTGGDVKTEFLHLIDHL
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