GenomeNet

Database: Pfam
Entry: P22_Tail-4
LinkDB: P22_Tail-4
Original site: P22_Tail-4 
#=GF ID   P22_Tail-4
#=GF AC   PF11650.7
#=GF DE   P22 tail accessory factor
#=GF AU   Pollington J, Finn RD
#=GF SE   PRODOM
#=GF GA   19.40 19.40;
#=GF TC   21.90 21.30;
#=GF NC   19.20 18.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   P22_phage
#=GF RN   [1]
#=GF RM   16970964
#=GF RT   Binding-induced stabilization and assembly of the phage P22 tail
#=GF RT   accessory factor gp4. 
#=GF RA   Olia AS, Al-Bassam J, Winn-Stapley DA, Joss L, Casjens SR,
#=GF RA   Cingolani G; 
#=GF RL   J Mol Biol. 2006;363:558-576.
#=GF DR   INTERPRO; IPR020362;
#=GF CC   This tail accessory factor of the P22 virus is also referred to
#=GF CC   as gene product 4 (Gp4). The proteins structure consists of 60%
#=GF CC   alpha helices. Gp4 is the first tail accessory factor to be
#=GF CC   added to newly DNA-filled capsids during P22-morphogenesis. In
#=GF CC   solution, the protein acts as a monomer and has low structural
#=GF CC   stability. The interaction of gp4 with the portal protein
#=GF CC   involves the binding of two non-equivalent sets of six gp4
#=GF CC   proteins [1]. Gp4 acts as a structural adaptor for gp10 and
#=GF CC   gp26, the other tail accessory factors [1].
#=GF SQ   15
#=GS A0A0G3QBS3_KLUIN/1-162  AC A0A0G3QBS3.1
#=GS A0A0A1B5A7_9GAMM/1-166  AC A0A0A1B5A7.1
#=GS A9MNM0_SALAR/1-162      AC A9MNM0.1
#=GS J7TAR5_MORMO/1-163      AC J7TAR5.1
#=GS A0A0S8KYL7_9PROT/2-151  AC A0A0S8KYL7.1
#=GS E6WS70_PSEUU/2-129      AC E6WS70.1
#=GS A0A069PH61_9BURK/5-154  AC A0A069PH61.1
#=GS EXLYS_BPP22/1-161       AC P26746.1
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI P; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI T; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI M; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI N; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI O; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI L; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI V; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI R; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI K; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI S; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI U; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI Q; 14-159;
#=GS I2B9R0_SHIBC/1-159      AC I2B9R0.1
#=GS A0A0R0CIR4_9GAMM/2-136  AC A0A0R0CIR4.1
#=GS C4K6U9_HAMD5/1-159      AC C4K6U9.1
#=GS A0A0S9MUJ5_9BURK/1-138  AC A0A0S9MUJ5.1
#=GS A0A0F5JUJ7_9BURK/5-149  AC A0A0F5JUJ7.1
#=GS Q2G3Z0_NOVAD/15-141     AC Q2G3Z0.1
#=GS B9TAJ3_RICCO/8-154      AC B9TAJ3.1
A0A0G3QBS3_KLUIN/1-162             ...........................................................M.LIATKGDLVRAALRKLGIASDAALTDVEPQSIQDAVDDLESMMAEWYQDGKGIITGYEFADPDNPPAEGDEHGLRSRAVSAVIHNLACRIAPDYALEATAKIITTARNGKELLYK.QTA.I.--ARAT.RSPYPNRMPIGSGNSFATLNGWHFFPGEQQ.DADSTTP-a................
A0A0A1B5A7_9GAMM/1-166             ...........................................................M.NLTTKGDIVRAALRKLGVASDATLTDVEPQSMQDAVEDLELMMAEWYQDGKGIITGYLFSDLDVPPFDGDPHGMLTSSISAVMHNLAVRIAPDYAVEPASKVVMNARNGKELLYK.NTA.L.SRARAAgRSGYPSRMPVGSGNRGAAMNNWNYFHRQEFdDADNTT--sv...............
A9MNM0_SALAR/1-162                 ...........................................................M.QIKTKGDLVMAALRKLGVASDATLTDVEPQSMQDAVDDLEAMMAEWYQGGKGIITGYVFSDDDNPPSEGDDHGLRSSAVSAVFHNLACRIAPDYALEATAKIIATAKYGKELLYK.QTA.I.--ARAK.RAPYPSRMPTGSGNSFANLNEWHYFPGEQ-.NADSTT--spd..............
J7TAR5_MORMO/1-163                 ...........................................................M.QILTKGELVVAALRKIGVASDATLTDIEPQSLEDGVNDLEAMMFEWHEDGKGIITGYKFAPDDTPIDQGDDHGISKAAISAVIYNLALRIAPDYQIAPLDKVITTARYGKERLLR.TVS.L.RKAREA.RSHYPNGFPIGSGNRLATMNGYRYFHRSKD.NAED----sgs..............
A0A0S8KYL7_9PROT/2-151             .........................................................gw-.---TKRDIIEQAFDEIGLAG--YVFDLQPQQLDSALRRLDNMMATWN--GKGIRIGYALPSSPGSSDLDQESGVTDMAIEAMALNLAIRLGPGYGRAIAPETKAAATMAYKQLLM.TSAqI.VEQQLG.----DGTIPSGAGNKG--------------.--------wryyndpflvppqdplq
E6WS70_PSEUU/2-129                 .......................................................akvq-.------EIVARALRLIQVQ-D-ARQPVKAVDMQTGIAVLNAMCARWEANGLAI--GWRPVSN-----PSEDMPCPPEAEEAIAFNLALTLAPEYGTEAPGIVVGAAARGLSDLRA.DVK.AsNPLRPD.RGVLPH------------------------.--------gydtrtd..........
A0A069PH61_9BURK/5-154             ...........................................ksyfveqglaelglsg-.----------------------AVYDFEPEDLERISNRLDANLAELESKGARI-PGWQFADAPGVSNLSTEVNIPTALVNLVILSAAIVAAPSIGKSLHSVTVAQLKIARDNLLF.FNK.P.IPQYQR.----PSNMPVGSGNQPW-ADGVQFYPQRPP.--------kldagpd..........
EXLYS_BPP22/1-161                  ...........................................................M.QIKTKGDLVRAALRKLGVASDATLTDVEPQSMQDAVDDLEAMMAEWYQDGKGIITGYVFSDDENPPAEGDDHGLRSSAVSAVFHNLACRIAPDYALEATAKIIATAKYGKELLYK.QTA.I.--SRAK.RAPYPSRMPTGSGNSFANLNEWHYFPGEQ-.NADSTTP-h................
#=GR EXLYS_BPP22/1-161       SS    ...........................................................X.XXX--SSSSSHHHHHHHHHHHHTSSSSSSSSSSHHHHHHHHHHHHSSSGGSSSSSSEES-SSSSSSSSSSEE---STTHHHHHHHHHHHSTGGGTS---HHHHHHHHHHHHHHTH.HHH.H.--HHTS.--SS-STS--TSSSSSSSSSSBSS--XXX-.XXXXXXX-X................
I2B9R0_SHIBC/1-159                 ...........................................................MaTTLTKGDIVLFALRKPAIASNASLTDVEPQSVEDAIQDLENMMYEWQINPGDI--GYLFAADGEEPLPDDDSGLPRKYMQAVGYQLMLRILSDYNLEPSSGVLINAQRSYDALLT.DTL.I.VPSMRR.RG----DFPVGQGNKYDLYTADRYYLGDLP.PIDGDVPN.................
A0A0R0CIR4_9GAMM/2-136             tavadivrdalqilgvvdpneapeaedeatairalnlmcrawevqgmtlgwqdvsgpge-.----------------------------------------------------------------------ELPAPPEAEEAIAYNLALRLRPRYGTELSADIVQQANDGLATLSA.QIT.A.--NTFA.RTEFP-DLPAGVGSRFGS------------.--------wrdgff...........
C4K6U9_HAMD5/1-159                 ...........................................................MtKPLTKGEIVLFALRKAGIASEATNIDVEPQSFEEGINDLEDLMAELQITFGDL--GYQFSAEEENPTADDASGLPRKYKQVMGYQLMLRMLSDYGIEPTPRQEASAAAAYDALLT.DTL.S.VPSIAR.RG----DMPVGQGNNYTALGTASYYVERGF.HAKNADPV.................
A0A0S9MUJ5_9BURK/1-138             ........................................................msw-.---TKRALVSEAFSELGLAG--YEFDLSPEEQIGALRRLDSMVAAWEEDGIRL--GYLLPTSPEDSDPDDDSGIPDTAAETVYLQLAIRIGPSFGKALNATTRKVATDGYARLLR.RAS.V.VPQMSR.P-----------------------------.--------rvlagagnrgrahgrv.
A0A0F5JUJ7_9BURK/5-149             ...........................................kswfvaegiaelglag-.----------------------AAVDMDPEMIERVSLRLDANLAELETKGARV-SGWVFSSEPAVNNGGVVVNIPNGLVNLVILSAAIVAAPSIGKNLSSVTVAQLKLARDNLMNfQSS.N.IPSMRR.NT----NMPFGSGNQQMA------------.--------dgpqfyrrlppq.....
Q2G3Z0_NOVAD/15-141                ..................................lvdlaylalgmtdtmfgrteeeyas-.----------------------------------GVGLLRAMMGEWPFD--QL--GYDY----TTPRPSERSGIEQKWTQAVSLSLAERIAPAVGKALSPQSASAKARSYSTLCA.AVG.N.----KS.TVTYPNNTPAGAGQ----------------.--------grslgfgaf........
B9TAJ3_RICCO/8-154                 .............................................fvenglaelglsga-.-----------------------VWDFPPEEMERICNRLDANLAELETKGARV-RGWVFADTPDGANSATVVNIPTGLVNLVILSAAIVAAPSIGKNLSSVTVAQLKLARDNLLF.FGK.R.IPQYQR.NT----NMPVGSGNQVWA-DGVQFYVNRPP.RVD-----agpd.............
#=GC SS_cons                       ...........................................................X.XXX--SSSSSHHHHHHHHHHHHTSSSSSSSSSSHHHHHHHHHHHHSSSGGSSSSSSEES-SSSSSSSSSSEE---STTHHHHHHHHHHHSTGGGTS---HHHHHHHHHHHHHHTH.HHH.H.--HHTS.--SS-STS--TSSSSSSSSSSBSS--XXX-.XXXXXXX-X................
#=GC seq_cons                      ................................................................TKt-lV..AhcchulAu..slhDl-PpshpculscL-uMMAEWppcGtsI..GYhFusssssss.u--pGlsspulpAVhasLAlRlAPcYGhphoupslusAphuh-pLhp.psu.h...shtc.Rs..PtshPsGuGNphhs.st.paa.tp...........th...............
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