GenomeNet

Database: Pfam
Entry: P22_Tail-4
LinkDB: P22_Tail-4
Original site: P22_Tail-4 
#=GF ID   P22_Tail-4
#=GF AC   PF11650.6
#=GF DE   P22 tail accessory factor
#=GF AU   Pollington J, Finn RD
#=GF SE   PRODOM
#=GF GA   19.40 19.40;
#=GF TC   21.90 21.30;
#=GF NC   18.90 18.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   P22_phage
#=GF RN   [1]
#=GF RM   16970964
#=GF RT   Binding-induced stabilization and assembly of the phage P22 tail
#=GF RT   accessory factor gp4. 
#=GF RA   Olia AS, Al-Bassam J, Winn-Stapley DA, Joss L, Casjens SR,
#=GF RA   Cingolani G; 
#=GF RL   J Mol Biol. 2006;363:558-576.
#=GF DR   INTERPRO; IPR020362;
#=GF CC   This tail accessory factor of the P22 virus is also referred to
#=GF CC   as gene product 4 (Gp4). The proteins structure consists of 60%
#=GF CC   alpha helices. Gp4 is the first tail accessory factor to be
#=GF CC   added to newly DNA-filled capsids during P22-morphogenesis. In
#=GF CC   solution, the protein acts as a monomer and has low structural
#=GF CC   stability. The interaction of gp4 with the portal protein
#=GF CC   involves the binding of two non-equivalent sets of six gp4
#=GF CC   proteins [1]. Gp4 acts as a structural adaptor for gp10 and
#=GF CC   gp26, the other tail accessory factors [1].
#=GF SQ   14
#=GS A0A0G3QBS3_KLUIN/1-162  AC A0A0G3QBS3.1
#=GS A0A0A1B5A7_9ENTR/1-166  AC A0A0A1B5A7.1
#=GS A9MNM0_SALAR/1-162      AC A9MNM0.1
#=GS J7TAR5_MORMO/1-163      AC J7TAR5.1
#=GS F0FW95_9BURK/156-231    AC F0FW95.1
#=GS I6HA51_SHIFL/1-165      AC I6HA51.1
#=GS E6WS70_PSEUU/2-129      AC E6WS70.1
#=GS EXLYS_BPP22/1-161       AC P26746.1
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI P; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI T; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI M; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI N; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI O; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI L; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI V; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI R; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI K; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI S; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI U; 14-159;
#=GS EXLYS_BPP22/1-161       DR PDB; 5GAI Q; 14-159;
#=GS I2B9R0_SHIBC/1-159      AC I2B9R0.1
#=GS D4BUK6_PRORE/1-157      AC D4BUK6.1
#=GS C4K6U9_HAMD5/1-159      AC C4K6U9.1
#=GS A0A0F5JUJ7_9BURK/5-149  AC A0A0F5JUJ7.1
#=GS Q2G3Z0_NOVAD/15-141     AC Q2G3Z0.1
#=GS B9TAJ3_RICCO/8-154      AC B9TAJ3.1
A0A0G3QBS3_KLUIN/1-162             .........................M.LIATKGDLVRAALRKLGIASDAALTDVEPQSIQDAVDDLESMMAEWY..QDGKGIITGYEFADPDNPPAEGDEHGLRSRAVSAVIHNLACRIAPDYALEATAKIITTARNGKELLYK.QTAI.--ARAT..RSPYPNRMPIGSGNSFATLNGWHFFPGEQQ.DADSTTP-a............
A0A0A1B5A7_9ENTR/1-166             .........................M.NLTTKGDIVRAALRKLGVASDATLTDVEPQSMQDAVEDLELMMAEWY..QDGKGIITGYLFSDLDVPPFDGDPHGMLTSSISAVMHNLAVRIAPDYAVEPASKVVMNARNGKELLYK.NTAL.SRARAA.gRSGYPSRMPVGSGNRGAAMNNWNYFHRQEFdDADNTT--sv...........
A9MNM0_SALAR/1-162                 .........................M.QIKTKGDLVMAALRKLGVASDATLTDVEPQSMQDAVDDLEAMMAEWY..QGGKGIITGYVFSDDDNPPSEGDDHGLRSSAVSAVFHNLACRIAPDYALEATAKIIATAKYGKELLYK.QTAI.--ARAK..RAPYPSRMPTGSGNSFANLNEWHYFPGEQ-.NADSTT--spd..........
J7TAR5_MORMO/1-163                 .........................M.QILTKGELVVAALRKIGVASDATLTDIEPQSLEDGVNDLEAMMFEWH..EDGKGIITGYKFAPDDTPIDQGDDHGISKAAISAVIYNLALRIAPDYQIAPLDKVITTARYGKERLLR.TVSL.RKAREA..RSHYPNGFPIGSGNRLATMNGYRYFHRSKD.NAED----sgs..........
F0FW95_9BURK/156-231               ...................alpqfv-.-----------------------------------------------..-------------------TPADDINLPPEYMAAIRYSLACYLAPSYQLEPQPALVRLAMNAKRIVKR.MNVQ.IQSM--..------------------------------.--------smprglatkqryn
I6HA51_SHIFL/1-165                 .........................M.NLTTKGDLVLAALRKLGVASNATLTDVEPQSMEDGVNDLEMMMAEWLggDASPGINVGYIFADADVAPDPGDEHGLSNNAINAVIFNLACRIAPDYALEASAKLIATARYGKERLVK.LSAM.DRAKAAkcKSGYPNRMPVGSGNQLAKWNGWNYFHRKEP.--------cdngs........
E6WS70_PSEUU/2-129                 .....................akvq-.------EIVARALRLIQVQ-D-ARQPVKAVDMQTGIAVLNAMCARWE..ANGLAI--GWRPVSN-----PSEDMPCPPEAEEAIAFNLALTLAPEYGTEAPGIVVGAAARGLSDLRA.DVKAsNPLRPD..RGVLPH------------------------.--------gydtrtd......
EXLYS_BPP22/1-161                  .........................M.QIKTKGDLVRAALRKLGVASDATLTDVEPQSMQDAVDDLEAMMAEWY..QDGKGIITGYVFSDDENPPAEGDDHGLRSSAVSAVFHNLACRIAPDYALEATAKIIATAKYGKELLYK.QTAI.--SRAK..RAPYPSRMPTGSGNSFANLNEWHYFPGEQ-.NADSTTP-h............
#=GR EXLYS_BPP22/1-161       SS    .........................X.XXX--SSSSSHHHHHHHHHHHHTSSSSSSSSSSHHHHHHHHHHHHSS..SGGSSSSSSEES-SSSSSSSSSSEE---STTHHHHHHHHHHHSTGGGTS---HHHHHHHHHHHHHHTH.HHHH.--HHTS..--SS-STS--TSSSSSSSSSSBSS--XXX-.XXXXXXX-X............
I2B9R0_SHIBC/1-159                 .........................MaTTLTKGDIVLFALRKPAIASNASLTDVEPQSVEDAIQDLENMMYEWQ..INPGDI--GYLFAADGEEPLPDDDSGLPRKYMQAVGYQLMLRILSDYNLEPSSGVLINAQRSYDALLT.DTLI.VPSMRR..RG----DFPVGQGNKYDLYTADRYYLGDLP.PIDGDVPN.............
D4BUK6_PRORE/1-157                 ........................m-.-TLTKGEIVLFALRKAGVASDATLTDVEPQSVEDGIHDLEDLMSEMQ..ITFGDL--GYKFSLEDEQPTPDDDSGLPRKYKQAIGYQLLLRILTDYGLEPTPRQEASAASSYDALLL.DTVS.VPSIDR..RG----DMPVGQGNKYTALGVDNYYVERGF.NATGK---dst..........
C4K6U9_HAMD5/1-159                 .........................MtKPLTKGEIVLFALRKAGIASEATNIDVEPQSFEEGINDLEDLMAELQ..ITFGDL--GYQFSAEEENPTADDASGLPRKYKQVMGYQLMLRMLSDYGIEPTPRQEASAAAAYDALLT.DTLS.VPSIAR..RG----DMPVGQGNNYTALGTASYYVERGF.HAKNADPV.............
A0A0F5JUJ7_9BURK/5-149             .........kswfvaegiaelglag-.----------------------AAVDMDPEMIERVSLRLDANLAELE..TKGARV-SGWVFSSEPAVNNGGVVVNIPNGLVNLVILSAAIVAAPSIGKNLSSVTVAQLKLARDNLMNfQSSN.IPSMRR..NT----NMPFGSGNQQMA------------.--------dgpqfyrrlppq.
Q2G3Z0_NOVAD/15-141                lvdlaylalgmtdtmfgrteeeyas-.----------------------------------GVGLLRAMMGEWP..FD--QL--GYDY----TTPRPSERSGIEQKWTQAVSLSLAERIAPAVGKALSPQSASAKARSYSTLCA.AVGN.----KS..TVTYPNNTPAGAGQ----------------.--------grslgfgaf....
B9TAJ3_RICCO/8-154                 ...........fvenglaelglsga-.-----------------------VWDFPPEEMERICNRLDANLAELE..TKGARV-RGWVFADTPDGANSATVVNIPTGLVNLVILSAAIVAAPSIGKNLSSVTVAQLKLARDNLLF.FGKR.IPQYQR..NT----NMPVGSGNQVWA-DGVQFYVNRPP.RVD-----agpd.........
#=GC SS_cons                       .........................X.XXX--SSSSSHHHHHHHHHHHHTSSSSSSSSSSHHHHHHHHHHHHSS..SGGSSSSSSEES-SSSSSSSSSSEE---STTHHHHHHHHHHHSTGGGTS---HHHHHHHHHHHHHHTH.HHHH.--HHTS..--SS-STS--TSSSSSSSSSSBSS--XXX-.XXXXXXX-X............
#=GC seq_cons                      .............................hTKG-lVhhALRKhulASsAslsDVEPQShp-ulsDLEsMMAEW...tsutsl..GYhFuspsssPssuD-pGlssphhsAVhasLAhRIAPDYulEsoupllusAphu+-tLhp.posh...uhtp..Ru....pMPsGuGNphsshst.paa.tp....hp.....s.s..........
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