LinkDB: PF02463
Original site: PF02463
Gene (145823) KEGG GENES (145823) Protein sequence (18110) UniProt (18110) 3D Structure (21) PDB (20) SCOP (1) Protein domain (2) InterPro (1) PROSITE(DOC) (1) Literature (2) PubMed (2) All databases (163958)
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#=GF ID SMC_N #=GF AC PF02463.14 #=GF DE RecF/RecN/SMC N terminal domain #=GF AU Bateman A #=GF SE [1] #=GF GA 40.00 40.00; #=GF TC 40.00 40.00; #=GF NC 39.90 39.90; #=GF BM hmmbuild --handHMM.ann SEED.ann #=GF SM hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq #=GF TP Family #=GF NE PF04423; #=GF NL Q12267.1/295-1321 #=GF NE PF06470; #=GF NL Q12267.1/295-1321 #=GF RN [1] #=GF RM 10429180 #=GF RT Structural maintenance of chromosomes (SMC) proteins: conserved #=GF RT molecular properties for multiple biological functions. #=GF RA Strunnikov AV, Jessberger R; #=GF RL Eur J Biochem 1999;263:6-13. #=GF RN [2] #=GF RM 9640531 #=GF RT SMC protein complexes and higher-order chromosome dynamics. #=GF RA Hirano T; #=GF RL Curr Opin Cell Biol 1998;10:317-322. #=GF DR INTERPRO; IPR003395; #=GF DR PROSITE; PDOC00539; #=GF DR HOMSTRAD; ABC_tran; #=GF DR SCOP; 1f2t; fa; #=GF CC This domain is found at the N terminus of SMC proteins. The SMC #=GF CC (structural maintenance of chromosomes) superfamily proteins #=GF CC have ATP-binding domains at the N- and C-termini, and two #=GF CC extended coiled-coil domains separated by a hinge in the middle. #=GF CC The eukaryotic SMC proteins form two kind of heterodimers: the #=GF CC SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute #=GF CC an essential part of higher order complexes, which are involved #=GF CC in chromatin and DNA dynamics [1]. This family also #=GF CC includes the RecF and RecN proteins that are involved in DNA #=GF CC metabolism and recombination. #=GF SQ 12849 #=GS C9VHH6_9RHIZ/2-1136 AC C9VHH6.1 #=GS D1WM58_STAEP/3-1171 AC D1WM58.1 #=GS H5P7V5_ECOLX/1-514 AC H5P7V5.1 #=GS C0EA14_9CLOT/2-358 AC C0EA14.1 #=GS D6SAW9_PEPMA/2-1155 AC D6SAW9.1 #=GS C6RP22_ACIRA/1-509 AC C6RP22.1 #=GS G3IWQ5_9GAMM/2-356 AC G3IWQ5.1 #=GS C2TKG9_BACCE/2-1173 AC C2TKG9.1 #=GS G2I9R6_9CLOT/2-356 AC G2I9R6.1 #=GS Q6P2R1_HUMAN/3-665 AC Q6P2R1.1 #=GS A4QFD2_CORGB/2-1138 AC A4QFD2.1 #=GS A0KVI2_SHESA/2-689 AC A0KVI2.1 #=GS F6FYR9_RALS8/1-510 AC F6FYR9.1 #=GS B5YFF1_DICT6/2-343 AC B5YFF1.1 #=GS F7JVN3_9FIRM/174-633 AC F7JVN3.1 #=GS F8F899_PAEMK/1-519 AC F8F899.1 #=GS H9ZRT1_THETH/6-996 AC H9ZRT1.1 #=GS E7KE91_YEASA/1-1135 AC E7KE91.1 #=GS C7P804_METFA/685-1163 AC C7P804.1 #=GS H2Z795_CIOSA/5-1164 AC H2Z795.1 #=GS B0H3T6_YERPE/1-514 AC B0H3T6.1 #=GS D4DZL7_SEROD/2-357 AC D4DZL7.1 #=GS A0YTB3_LYNSP/3-1211 AC A0YTB3.1 #=GS F0E9Z8_9PSED/1-515 AC F0E9Z8.1 #=GS H6MFC5_ECOLX/5-755 AC H6MFC5.1 #=GS H3EH96_PRIPA/10-882 AC H3EH96.1 #=GS F1X3Q9_MORCA/2-1191 AC F1X3Q9.1 #=GS Q7PAX7_RICSI/1-506 AC Q7PAX7.1 #=GS E4QGC4_BORBN/2-811 AC E4QGC4.1 #=GS F5WK33_STAAU/1-515 AC F5WK33.1 #=GS B1RIA3_CLOPF/1-513 AC B1RIA3.1 #=GS I0YMD8_9CHLO/16-1202 AC I0YMD8.1 #=GS H8LSP0_CORPS/1-530 AC H8LSP0.1 #=GS H1YWC5_9EURY/2-1137 AC H1YWC5.1 #=GS B2N6B0_ECOLX/2-356 AC B2N6B0.1 #=GS D4LHP9_9FIRM/1-87 AC D4LHP9.1 #=GS G1LKK8_AILME/56-1075 AC G1LKK8.1 #=GS H0W9V2_CAVPO/2-341 AC H0W9V2.1 #=GS RECF_LISIN/2-368 AC Q92FU8.1 #=GS G6GAB3_9FIRM/1-513 AC G6GAB3.1 #=GS E0HWX3_9BACT/3-1160 AC E0HWX3.1 #=GS E5VL62_9FIRM/212-705 AC E5VL62.1 #=GS A4RUQ7_OSTLU/10-1214 AC A4RUQ7.1 #=GS F4UFK6_ECOLX/2-356 AC F4UFK6.1 #=GS G7EA48_MIXOS/58-1269 AC G7EA48.1 #=GS B6W317_9BACE/2-364 AC B6W317.1 #=GS Q9SHT1_ARATH/40-315 AC Q9SHT1.2 #=GS A4N876_HAEIF/2-356 AC A4N876.1 #=GS F5RM58_9FIRM/2-1172 AC F5RM58.1 #=GS B2D9H2_UREPR/283-964 AC B2D9H2.1 #=GS F5IIR2_ACIBA/2-351 AC F5IIR2.1 #=GS A5ISB9_STAA9/3-665 AC A5ISB9.1 #=GS A3U8W5_CROAH/1-512 AC A3U8W5.1 #=GS A4ECR8_9ACTN/4-366 AC A4ECR8.1 #=GS D2RCN7_GARV4/2-397 AC D2RCN7.1 #=GS C3FQ72_BACTB/22-549 AC C3FQ72.1 #=GS F0P5G0_STAPE/1-515 AC F0P5G0.1 #=GS H6QKL1_RICMA/5-359 AC H6QKL1.1 #=GS E4FZC5_PROAA/1-515 AC E4FZC5.1 #=GS C6LY72_GIAIB/5-1417 AC C6LY72.1 #=GS G8NI05_BRUSS/2-1136 AC G8NI05.1 #=GS F3LD90_9GAMM/1-517 AC F3LD90.1 #=GS F1SH51_PIG/83-1274 AC F1SH51.1 #=GS Q874Z0_PODAS/145-1176 AC Q874Z0.1 #=GS G2I547_GLUXN/1-533 AC G2I547.1 #=GS RECF_HAES2/2-356 AC B0UUM0.1 #=GS B4LUF6_DROVI/81-1280 AC B4LUF6.1 #=GS C9IYK2_HUMAN/83-172 AC C9IYK2.1 #=GS F1VLL4_PROAA/1-515 AC F1VLL4.1 #=GS C5X880_SORBI/5-1037 AC C5X880.1 #=GS G6TMI4_STRPN/1-513 AC G6TMI4.1 #=GS RECF_VIBFM/2-357 AC B5FEV5.1 #=GS H9FRR7_MACMU/52-1068 AC H9FRR7.1 #=GS C7XIM7_9LACO/703-1173 AC C7XIM7.1 #=GS F8P1C8_SERL9/2-141 AC F8P1C8.1 #=GS G4GEV1_9EURY/2-1176 AC G4GEV1.1 #=GS D9XS43_9ACTO/1-532 AC D9XS43.1 #=GS E4TEW8_CALNY/2-1110 AC E4TEW8.1 #=GS F3A995_9BACL/2-1166 AC F3A995.1 #=GS E4STW8_STRTN/2-361 AC E4STW8.1 #=GS F7FZ50_ORNAN/51-1073 AC F7FZ50.1 #=GS D3IIA6_9BACT/1-513 AC D3IIA6.1 #=GS Q7Q3D7_ANOGA/71-1270 AC Q7Q3D7.2 #=GS A5JZH3_PLAVS/2-1183 AC A5JZH3.1 #=GS Q45KY9_TOXGO/153-1420 AC Q45KY9.1 #=GS A4YZJ4_BRASO/1-510 AC A4YZJ4.1 #=GS F3PQG0_9BACE/1-513 AC F3PQG0.1 #=GS G6CAQ2_9STRE/1-513 AC G6CAQ2.1 #=GS E5R5H6_STAAG/2-368 AC E5R5H6.1 #=GS H0Q967_ECOLI/1-514 AC H0Q967.1 #=GS H4NVT8_ECOLX/2-356 AC H4NVT8.1 #=GS H2CGM8_9LEPT/2-342 AC H2CGM8.1 #=GS B2FDA8_CAEEL/2-1241 AC B2FDA8.1 #=GS E1NS97_9LACO/2-341 AC E1NS97.1 #=GS C7LZB1_ACIFD/1-477 AC C7LZB1.1 #=GS B0CI24_BRUSI/15-378 AC B0CI24.1 #=GS A5UQ60_ROSS1/2-1187 AC A5UQ60.1 #=GS B3S8C6_TRIAD/1-831 AC B3S8C6.1 #=GS Q63R40_BURPS/1-508 AC Q63R40.1 #=GS Q1V0M1_PELUQ/2-843 AC Q1V0M1.1 #=GS G7H550_9ACTO/2-1188 AC G7H550.1 #=GS H2HFF8_CORDP/2-1141 AC H2HFF8.1 #=GS Q2CK39_9RHOB/2-1137 AC Q2CK39.1 #=GS D0C9I7_ACIBA/2-1131 AC D0C9I7.1 #=GS C1D6U4_LARHH/1-512 AC C1D6U4.1 #=GS F1XHG4_MORCA/1-516 AC F1XHG4.1 #=GS B1C162_9FIRM/2-148 AC B1C162.1 #=GS I0N8V1_STRPN/2-1165 AC I0N8V1.1 #=GS H8KYP8_FRAAD/2-1151 AC H8KYP8.1 #=GS B1FWE9_9BURK/1-515 AC B1FWE9.1 #=GS B5JMA0_9BACT/2-1264 AC B5JMA0.1 #=GS G7USZ2_PSEUP/2-344 AC G7USZ2.1 #=GS A9ZA35_YERPE/1-514 AC A9ZA35.1 #=GS C9LZF3_LACHE/1-517 AC C9LZF3.1 #=GS D6UB44_STAAU/696-1171 AC D6UB44.1 #=GS A4MES9_BURPE/1-508 AC A4MES9.1 #=GS B5ZWI3_RHILW/2-510 AC B5ZWI3.1 #=GS F0I2M2_STRSA/2-1166 AC F0I2M2.1 #=GS G9XB38_9FIRM/656-1162 AC G9XB38.1 #=GS G2IQ24_9SPHN/1-514 AC G2IQ24.1 #=GS E4D6Z5_PROAA/1-515 AC E4D6Z5.1 #=GS Q01BI2_OSTTA/14-1128 AC Q01BI2.1 #=GS RECF_RICFE/5-360 AC Q4UNG8.2 #=GS F7Q7H3_9GAMM/2-1156 AC F7Q7H3.1 #=GS H9KGP8_APIME/4-114 AC H9KGP8.1 #=GS RECF_LACLA/2-355 AC Q9CE70.1 #=GS E7JJY0_ECOLX/2-356 AC E7JJY0.1 #=GS G4QAB4_TAYAM/632-1158 AC G4QAB4.1 #=GS B6ACW3_CRYMR/759-1199 AC B6ACW3.1 #=GS G7RZG9_STRSU/2-361 AC G7RZG9.1 #=GS Q2FY50_STAA8/1-515 AC Q2FY50.1 #=GS H3ZEN2_9ALTE/2-362 AC H3ZEN2.1 #=GS F1UWD1_PROAA/9-378 AC F1UWD1.1 #=GS E6QPI9_9ZZZZ/42-907 AC E6QPI9.1 #=GS G2Q0N3_THIHA/74-1024 AC G2Q0N3.1 #=GS C4R6W0_PICPG/2-573 AC C4R6W0.1 #=GS D5WHL9_BURSC/2-867 AC D5WHL9.1 #=GS H2G375_CORDP/1-529 AC H2G375.1 #=GS RECF_LEPIC/2-343 AC Q72WD4.1 #=GS F9UUL1_MYCBO/2-359 AC F9UUL1.1 #=GS E4FN15_PROAA/9-378 AC E4FN15.1 #=GS D7UVJ4_LISGR/2-1171 AC D7UVJ4.1 #=GS G7DDW6_BRAJP/1-511 AC G7DDW6.1 #=GS D6LGQ0_9FUSO/2-1163 AC D6LGQ0.1 #=GS E7VGR4_SALMO/1-514 AC E7VGR4.1 #=GS C2V0C1_BACCE/5-532 AC C2V0C1.1 #=GS D2YK36_VIBMI/1-515 AC D2YK36.1 #=GS C2ENW2_9LACO/2-369 AC C2ENW2.1 #=GS C7Z1J1_NECH7/3-1239 AC C7Z1J1.1 #=GS D1BQ80_VEIPT/2-361 AC D1BQ80.1 #=GS E1SMV2_FERBD/2-1136 AC E1SMV2.1 #=GS G8S1F7_ACTS5/1-539 AC G8S1F7.1 #=GS B1BI55_CLOPF/2-360 AC B1BI55.1 #=GS C4FZI5_ABIDE/2-1174 AC C4FZI5.1 #=GS D3DFW6_HYDTT/52-479 AC D3DFW6.1 #=GS A3MKV2_BURM7/34-1187 AC A3MKV2.1 #=GS E8UZJ7_TERSS/3-136 AC E8UZJ7.1 #=GS B2GIG0_KOCRD/2-381 AC B2GIG0.1 #=GS C7N560_SLAHD/2-1159 AC C7N560.1 #=GS B3P775_DROER/106-1108 AC B3P775.1 #=GS A0JXV4_ARTS2/2-1212 AC A0JXV4.1 #=GS F0FER7_STRSA/1-513 AC F0FER7.1 #=GS B9WLG8_CANDC/3-1216 AC B9WLG8.1 #=GS A3XVM0_9VIBR/1-515 AC A3XVM0.1 #=GS F5J648_9RHIZ/1-510 AC F5J648.1 #=GS Q9K078_NEIMB/1-511 AC Q9K078.1 #=GS H7IYC0_STRPN/1-513 AC H7IYC0.1 #=GS H1SKZ5_STAAU/3-665 AC H1SKZ5.1 #=GS C7WMN2_ENTFL/4-517 AC C7WMN2.1 #=GS B7DUN1_9BACL/2-363 AC B7DUN1.1 #=GS B5EFS9_GEOBB/2-1168 AC B5EFS9.1 #=GS Q1V4W0_VIBAL/2-357 AC Q1V4W0.1 #=GS D6T2K3_GARVA/1-538 AC D6T2K3.1 #=GS A5WN15_MYCTF/1-541 AC A5WN15.1 #=GS G8XJU0_MYCHR/3-151 AC G8XJU0.1 #=GS E3HLV2_ACHXA/1-508 AC E3HLV2.1 #=GS E1C611_CHICK/2-1170 AC E1C611.1 #=GS D4XKX7_ACIHA/2-350 AC D4XKX7.1 #=GS C5VX31_STRSE/2-1165 AC C5VX31.1 #=GS B4HRQ4_DROSE/2-1165 AC B4HRQ4.1 #=GS Q5CGG0_CRYHO/2-726 AC Q5CGG0.1 #=GS G7W5E9_DESOD/2-903 AC G7W5E9.1 #=GS F5W1D5_9STRE/2-361 AC F5W1D5.1 #=GS G2YGL0_BOTF4/1-1209 AC G2YGL0.1 #=GS B5RQM6_BORRA/6-817 AC B5RQM6.1 #=GS B2P423_ECO57/2-356 AC B2P423.1 #=GS A5W9A5_PSEP1/1-515 AC A5W9A5.1 #=GS F8FTV8_PSEPU/2-1147 AC F8FTV8.1 #=GS B6JB44_OLICO/1-513 AC B6JB44.1 #=GS Q12AD2_POLSJ/2-1165 AC Q12AD2.1 #=GS F6B3U4_DESCC/2-363 AC F6B3U4.1 #=GS D1Y3F5_9BACT/2-335 AC D1Y3F5.1 #=GS G5GLR4_9FIRM/1-518 AC G5GLR4.1 #=GS H5KL44_ECOLX/2-356 AC H5KL44.1 #=GS H8EQ99_CLOTM/2-365 AC H8EQ99.1 #=GS H7G7C5_STAA5/3-665 AC H7G7C5.1 #=GS F7ZQG8_CLOAT/776-1177 AC F7ZQG8.1 #=GS H6WNU7_9BACE/1-514 AC H6WNU7.1 #=GS A2EIA2_TRIVA/2-1080 AC A2EIA2.1 #=GS Q5FPF7_GLUOX/7-1496 AC Q5FPF7.1 #=GS F9NJI5_STREQ/2-362 AC F9NJI5.1 #=GS H3M8X6_KLEOX/1-514 AC H3M8X6.1 #=GS B2GWM6_BURPE/2-1155 AC B2GWM6.1 #=GS D1J8Q8_MYCHP/2-961 AC D1J8Q8.1 #=GS D7XPZ0_ECOLX/1-514 AC D7XPZ0.1 #=GS RECF_SALEP/2-356 AC B5QUP8.1 #=GS A6AJC0_VIBCL/2-173 AC A6AJC0.1 #=GS D7I3X5_PSESS/1-515 AC D7I3X5.1 #=GS E0Y140_9PROT/2-1137 AC E0Y140.1 #=GS D0CG09_ACIBA/2-351 AC D0CG09.1 #=GS E8DMX5_SALMO/2-356 AC E8DMX5.1 #=GS A6AQ90_VIBHA/1-514 AC A6AQ90.1 #=GS E5TE44_STAAU/696-1171 AC E5TE44.1 #=GS I0E6T6_HELPX/8-486 AC I0E6T6.1 #=GS C1CVD0_DEIDV/4-492 AC C1CVD0.1 #=GS H2YJF9_CIOSA/2-1177 AC H2YJF9.1 #=GS F3ZMS1_9ACTO/5-539 AC F3ZMS1.1 #=GS D2GDB7_STAAU/2-368 AC D2GDB7.1 #=GS C6ILA3_9BACE/2-363 AC C6ILA3.1 #=GS Q1GIU1_SILST/1-508 AC Q1GIU1.1 #=GS RECF_STRGC/2-361 AC A8AU71.1 #=GS E4T223_PALPW/2-360 AC E4T223.1 #=GS H4TF10_ECOLX/2-356 AC H4TF10.1 #=GS C8LDJ1_STAAU/696-1171 AC C8LDJ1.1 #=GS A6QGD4_STAAE/3-665 AC A6QGD4.1 #=GS F0INU1_STRSA/1-513 AC F0INU1.1 #=GS B5JZC8_9RHOB/1-337 AC B5JZC8.1 #=GS B7HDX1_BACC4/2-1173 AC B7HDX1.1 #=GS G0UUM0_TRYCI/4-1244 AC G0UUM0.1 #=GS A5GPU1_SYNPW/1-520 AC A5GPU1.1 #=GS H4AKL7_STAAU/696-1171 AC H4AKL7.1 #=GS E0TMT8_STRZ6/1-513 AC E0TMT8.1 #=GS Q1ZL29_PHOAS/2-358 AC Q1ZL29.1 #=GS H4E0E3_STAAU/1-515 AC H4E0E3.1 #=GS G9V6E2_SALMO/1-514 AC G9V6E2.1 #=GS G6UFD2_STRPN/2-361 AC G6UFD2.1 #=GS B3XT85_UREUR/3-964 AC B3XT85.1 #=GS Q5DD31_SCHJA/7-212 AC Q5DD31.1 #=GS Q3DNE5_STRAG/1-1105 AC Q3DNE5.1 #=GS Q0CKT6_ASPTN/241-1432 AC Q0CKT6.1 #=GS D1CC09_THET1/2-1165 AC D1CC09.1 #=GS RECF_SHIF8/2-356 AC Q0SYP0.1 #=GS E2YL49_ENTFL/1-513 AC E2YL49.1 #=GS B4FN08_MAIZE/21-333 AC B4FN08.1 #=GS RECN_XYLFA/178-512 AC Q9PB02.1 #=GS E1MBR8_9ACTO/2-406 AC E1MBR8.1 #=GS C9LFM2_9BACT/1-340 AC C9LFM2.1 #=GS F0BX51_9XANT/1-512 AC F0BX51.1 #=GS RECF_CHLCV/2-361 AC Q823G6.1 #=GS G2G089_9FIRM/1-513 AC G2G089.1 #=GS H3XM66_STAAU/1-515 AC H3XM66.1 #=GS Q7A5Z2_STAAN/3-665 AC Q7A5Z2.1 #=GS E0RV40_BUTPB/2-1172 AC E0RV40.1 #=GS E5Y632_BILWA/1-495 AC E5Y632.1 #=GS F7JVN2_9FIRM/2-319 AC F7JVN2.1 #=GS RECF_CLOPS/2-360 AC Q0SWY1.1 #=GS F1X241_MORCA/2-1185 AC F1X241.1 #=GS C4FJG6_9AQUI/4-1149 AC C4FJG6.1 #=GS B4V5C2_9ACTO/2-568 AC B4V5C2.1 #=GS F1UEC3_PROAA/1-515 AC F1UEC3.1 #=GS G0I9U0_STRES/2-1165 AC G0I9U0.1 #=GS Q8DPN3_STRR6/1-513 AC Q8DPN3.1 #=GS G4D5W0_9FIRM/1-154 AC G4D5W0.1 #=GS E7R3U8_PICAD/327-1499 AC E7R3U8.1 #=GS F4TIY2_ECOLX/1-514 AC F4TIY2.1 #=GS D4ZIY3_SHEVD/2-1120 AC D4ZIY3.1 #=GS F0PBN4_ENTF6/344-849 AC F0PBN4.1 #=GS RECF_SALTY/2-356 AC P24900.3 #=GS C9A9K6_ENTCA/2-1172 AC C9A9K6.1 #=GS H3SZF9_PSEAE/1-515 AC H3SZF9.1 #=GS E4MPZ7_CAPOC/1-512 AC E4MPZ7.1 #=GS B0MDR3_9FIRM/1-514 AC B0MDR3.1 #=GS B6IR58_RHOCS/2-1159 AC B6IR58.1 #=GS B4L846_DROMO/205-1180 AC B4L846.1 #=GS C2TL70_BACCE/5-532 AC C2TL70.1 #=GS A5N7J6_CLOK5/1-517 AC A5N7J6.1 #=GS C5WJS8_STRDG/2-362 AC C5WJS8.1 #=GS D8ECC6_ECOLX/2-356 AC D8ECC6.1 #=GS A3PAB6_PROM0/5-1188 AC A3PAB6.1 #=GS A4Y804_SHEPC/2-407 AC A4Y804.1 #=GS A1AJX4_PELPD/2-362 AC A1AJX4.1 #=GS C3AG08_BACMY/2-368 AC C3AG08.1 #=GS E1NKW5_9LACO/1-516 AC E1NKW5.1 #=GS C6UC03_ECOBR/1-514 AC C6UC03.1 #=GS E0VYD1_PEDHC/2-1186 AC E0VYD1.1 #=GS E0RTB3_SPITD/1-334 AC E0RTB3.1 #=GS F8M8T2_MYCA0/1-541 AC F8M8T2.1 #=GS Q0C0X5_HYPNA/2-1137 AC Q0C0X5.1 #=GS D6J0U2_STAAU/1-515 AC D6J0U2.1 #=GS Q11MG7_MESSB/18-387 AC Q11MG7.1 #=GS C6CT00_PAESJ/2-368 AC C6CT00.1 #=GS F7QY98_9LACO/1-514 AC F7QY98.1 #=GS A1STE1_PSYIN/1-519 AC A1STE1.1 #=GS H5PBC9_ECOLX/2-356 AC H5PBC9.1 #=GS C7RBE2_KANKD/2-1150 AC C7RBE2.1 #=GS F5TW93_9ACTO/2-371 AC F5TW93.1 #=GS 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