#=GF ID   DUF531
#=GF AC   PF04407.7
#=GF DE   Protein of unknown function (DUF531)
#=GF AU   Waterfield DI, Finn RD
#=GF SE   COG1772
#=GF GA   25.00 25.00;
#=GF TC   80.50 79.40;
#=GF NC   21.00 20.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR007501;
#=GF CC   Family of hypothetical archaeal proteins.
#=GF SQ   38
#=GS D7DT04_METV3/28-205   AC D7DT04.1
#=GS O58326_PYRHO/2-177    AC O58326.1
#=GS F0LK48_THEBM/1-175    AC F0LK48.1
#=GS B7R3G6_9EURY/1-174    AC B7R3G6.1
#=GS C6A3N9_THESM/12-187   AC C6A3N9.1
#=GS Q8PWQ8_METMA/40-213   AC Q8PWQ8.1
#=GS C9RDT9_METVM/6-169    AC C9RDT9.1
#=GS D1YZQ2_METPS/1-175    AC D1YZQ2.1
#=GS Q8TZ83_METKA/7-184    AC Q8TZ83.1
#=GS H8IAZ2_METCZ/10-184   AC H8IAZ2.1
#=GS F6BCG0_METIK/52-215   AC F6BCG0.1
#=GS B6YTT3_THEON/1-174    AC B6YTT3.1
#=GS Q8U3Y6_PYRFU/1-176    AC Q8U3Y6.1
#=GS H1KWT0_9EURY/8-171    AC H1KWT0.1
#=GS F8AET8_PYRYC/1-175    AC F8AET8.1
#=GS D3S6N9_METSF/6-170    AC D3S6N9.1
#=GS D3RWY3_FERPA/1-165    AC D3RWY3.1
#=GS C5A2V4_THEGJ/1-174    AC C5A2V4.1
#=GS F2KRN4_ARCVS/1-164    AC F2KRN4.1
#=GS D2RD77_ARCPA/1-167    AC D2RD77.1
#=GS F4HNB8_PYRSN/1-176    AC F4HNB8.1
#=GS Y224_METJA/6-169      AC Q57677.1
#=GS D5VRB0_METIM/3-167    AC D5VRB0.1
#=GS F8AK47_METOI/6-169    AC F8AK47.1
#=GS F7XQQ3_METZD/1-174    AC F7XQQ3.1
#=GS G0HLH2_THES4/3-176    AC G0HLH2.1
#=GS Q46EI7_METBF/5-178    AC Q46EI7.1
#=GS H3ZJZ6_THELI/1-176    AC H3ZJZ6.1
#=GS Q9UYQ5_PYRAB/1-175    AC Q9UYQ5.1
#=GS B3T4Q1_9ZZZZ/331-485  AC B3T4Q1.1
#=GS D5E7U5_METMS/1-174    AC D5E7U5.1
#=GS Q0W266_UNCMA/1-175    AC Q0W266.1
#=GS Q12W36_METBU/1-174    AC Q12W36.1
#=GS C7P6V0_METFA/6-169    AC C7P6V0.1
#=GS Q5JDR7_PYRKO/3-176    AC Q5JDR7.1
#=GS A6UT28_META3/6-169    AC A6UT28.1
#=GS Q8TU36_METAC/5-178    AC Q8TU36.1
#=GS O29840_ARCFU/1-165    AC O29840.1
D7DT04_METV3/28-205              .r-CTMILYNSYDKSKWHEAHKRAIARAAPICTAFDWNLAIYDFPVDkienldgldT.-ANNEKDVIKlIETTIGGSGSYLRNLIDNNRFLITN----KYQAQF.GTPIATTSKPDPKKLITPKKVLEE-LQKKPCGVFIGLGRHGLPKDVMKMGHYDLDIT.EKGLSLETCTAIASIPAVISTMAKYe....
O58326_PYRHO/2-177               ..MLTIGLYNTYDPKRIHEAHLRAIARAAPVAYAFNFHLALIGFPFE.........GkDEREIAGEVA.ENTTIGEGGKYLIKLVESGKFHLLDFPKKGFPSQF.GEVVATTSKPSKEKAVKTIEIAEMAVRGKSFIFLIGLGRHGLPKEAFKIAKYHLDITdGKGISLETCTAIGIIPAKIATVMEAl....
F0LK48_THEBM/1-175               ..MLTLALYNSYDPKKVHEAHLRAIARAAPICYAFDFHLALIGFPFN.........E.KPLDLSEKIS.ENTTIGEGGKYLLELAKKNKFHLLEFPKRGFPPQF.GTIIATTRKPDEHKEISAIEVAKRALKGESFMLIVGLGRHGLPEEIFKLAEYHLDITdGKRISLETCTAIGSIPTKIRTLMEAl....
B7R3G6_9EURY/1-174               ..MLTLALYNTYDARKLHEAHLRAIARAGPIAYAFGFHLALVGFPLE.........G.KPIEVAEEVS.SHTTIGEGGTYLLELARRNRFHLLDFPRKGFPPQF.GTVVATTRKPEEEKEISPLELAERAFRGESFILLVGLGRHGLPGEIFKLARHHMDIT.GERISLETCTAIGAIPARIRTLMEAl....
C6A3N9_THESM/12-187              ..MLTLSLYNSYDPKKLHEAHLRAIARAAPICYAFDFHLALVGFPFE.........TkKPLEIGSEIS.KSTTIGESGKYLLELAKTNKFHLLDFPKLGFPPQF.GQIVATTRKPDENKNISSLQLAERALRGESFMLVVGLGRHGLPKEIFKLAKYHLDITdGKRISLETCTAIGSIPTKIRTLMEAl....
Q8PWQ8_METMA/40-213              ..MLTLGIVNTYDKIKVLDAHYRAIARAAPICHAFGFHLALYDFPFK.........M.TAEELVAFVM.EKTTIGESGSYLKILYEKNHLSVSDLPKKGFPSQF.GETVITTSKPDPKRKVMPVKIAEEALHNRSFLFLVGLGHKGLPKELFERGKYHLDIT.SKGLSLETCTAIGAVPAHLAGLMENl....
C9RDT9_METVM/6-169               ..RMTVILYNSYDKLRWHEAHKRAIARAAPICYAYDCNMAIMDFPCS.........-.----MEDILN.IKTTIGSSGKYLEQLIDENRFFIVD----KFLPQF.GVPIASTSKPEETKKISPQDVA-NLLNKKPVGIYIGLGRHGLPKDIMKTSVYHLDIT.EKNISLETCTAIGAIPAKIHTITQ-lq...
D1YZQ2_METPS/1-175               ..MLTLGLYNTYDKVKVVEAHYRGIARGAPIAYAYGFNLALVGFPYD.........F.SQQELVAFVK.DNTTIGGSGLYLQKLYDEKRLYVMDVPEKGFPAQF.GALVATTSKPEKKKKASAEEIADMMVKNKPLFILIGLGRKGLPKEYFEMAHYHLDITdGKGISLETCTAIGAIAARLYTLAEQk....
Q8TZ83_METKA/7-184               ..RVTIGLYNSYDPRRFHEIHARTIARAAPLCVAFDFKLALFGFPLDdl.....gvE.TPHELAEYVA.EETTIGASGREVLVLAERNLLEVYDYPVRGFPPQL.GTIVGTTCRPDERKAIEPEDVVREILRPRSVTLVFGLGRRGLPAEVLEACEYHLDIT.GRRISLETATAIGAVTAVIGHLIKKe....
H8IAZ2_METCZ/10-184              ..MLTLGLYNTYDKVKVVEAHYRGIARGAPIAYAYGFNLALIGFPYE.........F.EEKELVEFVK.DNTTIGASGLYLQKLYDEKRLFVMDVPEKGFPSQF.GSLVVTTSHPERKKNASAEEIADMMIKNRPLLILIGLGRKGLPKEYFEMAQYHLDITdGKGISLETCTAIGAIAARLYTIAE-fk...
F6BCG0_METIK/52-215              ..RMTLILYNSYDKNRWHEAHKRAIARAAPICYAFDCNLAIMEFPCK.........K.-----EDILS.IETTIGNSGEYLHKLIEKNRFLIID----KYLPQL.GIPIVATSKPDKKKAITPMDVV-NLLTKKPCGILVGLGRHGLPKDIVKMGEYHLDIT.GKGVSLETCTAIATIPAVISTYINAk....
B6YTT3_THEON/1-174               ..MLTVALYNTYDPRKLHEAHLRAIARAGPIAYAYGFHLALVGFPFE.........G.RPVDVAEEIA.SHTTIGEGGKYLLELAQRNRFHLLEFPKKGFPPQF.GTPVATTRKPSEEKEITPLELSERALKGESFLLLIGLGRHGLPKEIFKMARYHMDIT.GKRVSLETCTAIGAIPARISTLMEAl....
Q8U3Y6_PYRFU/1-176               ..MLTIGLYNTYDTKKLHEAHIRAIARAAPVAYAYEFHLALIGFPFD.........SdDPKEVAERVA.STTTIGEGGKYLLELAKSNKFHLLDFPKRGFPPQF.GEVIATTSKPSKEKVIGSREVAEMALRGKSLMLIIGLGRHGLPKEVFEISKYHLDITdGREISLETCTAIGIIPARIKTLMEAl....
H1KWT0_9EURY/8-171               ..RMTLILYNSYDKNRWHEAHKRAIARAAPICYAFDCNLAIMEFPCK.........K.-----EDILS.IETTIGNSGEYLRKLVEKNRFLIID----KYLPQL.GIPIIATSKPDKKKAITPMDVVD-LLTKKPCGILVGLGRHGLPKDIVKMGEYHLDIT.GKGVSLETCTAIASIPAVISTYINTt....
F8AET8_PYRYC/1-175               ..MLTIALYNTYDPKKLHETHLRAIARAAPVAHAFGFHLALVGFPLT.........G.KPLDVAEEVA.EHTTIGEGGKYLLELARANKFHLLDFPEKGFSPQF.GTPIATTSKPWEEKKITSLEVAERALRGESFIFLIGLGRHGLPKEIFKMARHHLDITdGLGVSLETCTAIGIIPARIKTLMEAl....
D3S6N9_METSF/6-170               ..RMTLILYNSYDKTRWHEAHKRAIARAAPICYAFDCNLAIMDFPCK.........-.---DVEDILN.IKTTIGNSGEYLEKLIEKNRFFIVD----KFLPQF.GIPIASTSKPDEKKAITPLDTA-HLLKKKPVGIYVGLGRHGLPKDIMESSLYHLDIT.EKKVSLETCTAIGCIPAVVYCYTKYi....
D3RWY3_FERPA/1-165               ..MITLCLVNTYDKLKLHEAHLRSIARIAPICYAFDFHLALYDFPFW.........K.REEEVVDAVC.DYTTIGEGGKYLRELHESGKFHLIE----SFESRF.GEIVATTSKPDESKKISLDDIARF----RSAIFLFGLGRKGLPKDVLKKAKYHFEAT.GKNVSLETCTAIGVVATLIWV----vrhg.
C5A2V4_THEGJ/1-174               ..MLTLALYNTYDTRKLHEAHLRAIARAGPIAYAFGFHLALVGFPLR.........G.RPLDVAEEVS.SHTTIGEGGTYLLELARRNRFHLLDFPRKGFPPQF.GTVVATTRKPSDEKEISPLELAERALRGESFIFLVGLGRHGLPGEIFKLARHHMDIT.GKRISLETCTAIGAIPAKIRTLMEAl....
F2KRN4_ARCVS/1-164               ..MFVLCLVNTYDKLKLHEIHLRSIARAAPLCYAFGLHLALLDFPFW.........K.ERDEVVKAVR.DYTTIGEHGRYLEELDKSGKFHLIE----KIPAHF.GVLVATTSKPDEGKRISTDDVPSL----TSATFLMGLGRKGLPKELMKKAKYHWDVT.GKGVSLETCAAMGVIAALVG-----ckhg.
D2RD77_ARCPA/1-167               ..MIVLCLVNTYDKLKKHEIHLRSIARAIPLCYAFDFHLALYDFNFW.........K.NEREMVDEVV.SYTTIGEP-DYAYQMLDKNKIHLID----NFPAHF.GELIATTPEPDRKKALSFEDMAR-VIRERSVTFLIGLGRRGLPKDLMERARYHFEAT.GRGVSLETCTAMGVIATTIH-----farvm
F4HNB8_PYRSN/1-176               ..MLTIGLYNTYDTRRIHEAHLRAIARAAPVAYAFNFHLALIGFPFE.........EkDEKEIAEEVA.SNTTIGGGGRYLIELANSGKFHLLDFPKRGFPPQF.GEIVATTSKPSREKVVKTIEIAEMALRGKSFIFLIGLGRHGLPKEAFKIAKYHLDITdGMGVSFETCTAIGIIPARIATIMEAl....
Y224_METJA/6-169                 ..RLTLILYNSYDKTRWHEAHKRAIARAAPICYAFDCNLAIMDFPCK.........-.----MEDILN.IKTTIGNSGEYLEKLIEKNRFFIVD----KFLPQF.GIPIASTSKPDEKKAITPLDTA-YLLKKKPIGVYVGLGRHGLPKDIMESCVYHLDVT.EKRVSLETCTAIGSIPAVIYCYTKYi....
D5VRB0_METIM/3-167               ..RITLILYNSYDKKRWHEAHKRAIARAAPVCWAYNCNLAIMDFPVE.........-.---DVEEVKE.ISTTIGDSGKYLRMLIENNKFFIVD----KFLSQF.GVPIASTSKPDKKKSITPEETI-GLLTKKPIGIFIGLGRHGLPKDILEFSKYHLDIT.KKGISLETCTAIGCIPATLYWI---gemy.
F8AK47_METOI/6-169               ..RMTLILYNSYDKSRWHEAHKRAIARAAPICYAFNCNLAIMDFPCK.........K.-----EDILS.IETTIGNSGEYLKELIDNNRFSIID----KYRAQF.GVPIITTSKPDERKLITPREIANL-LLKKPCGIFVGLGRHGLPKNIIKLSDYQLDIT.EKRVSLETCTAIATIPSVISTYLK-fl...
F7XQQ3_METZD/1-174               ..MLTMGLVNTYDRIKILDAHYRAIARAAPICYAFGFNLALFDFPFT.........M.ESDEMVDYVV.DKTTIGESGKYLRMLHESRRFYLSDLPKKGFQAHL.GHPVVTTSKPEEKFRTTPQQLVDEIMRKRSFLILVGLGRKGLPKNMYQLSRYHLDIT.SCGVSLETCTAIGAIAANIEGIA--agr..
G0HLH2_THES4/3-176               ..MLTIALYNTYDPKRLHEAHLRAIARAGPIAYAYGFHLALVGFPFE.........G.RPIDVAEEIS.GHTTIGEGGRYLMELAEGNRFHLLDFPRRGFPPQF.GTPVATTRKPSDGKELTPIELAERALRGESFLLLVGLGRHGLPKEIFKTARYHMDIT.GKRVSLETCTAIGAIPARISTLMEAl....
Q46EI7_METBF/5-178               ..MLTLGIVNTYDKIKVLDAHYRAIARAAPICHAFGFHLALYDFPFK.........M.TAEELVAYVM.EKTTIGESGSYLKILYEKNYLSVSDLPKKGFPSQF.GEIVITTSKPDPKRQVPPIKIAEEALRNRSFLFLVGLGHKGLPKELFERGRYHLDIT.CKGLSLETCTAIGAIPAHLSGLMVNf....
H3ZJZ6_THELI/1-176               ..MLTLALYNSYDPKKLHEAHLRAIARAAPICYAFDFHLALIGFPFE.........KkKPAEIAEEIS.QNTTIGEGGKYLIELARTNKFHLIEFPKGGFPPQF.GHIVATTRKPNKNKEISSHQLAERALKGESFMLIVGLGRHGLPKEIFKLANYHLDITdGKRISLETCTAIGSIPTKIRTIMEEl....
Q9UYQ5_PYRAB/1-175               ..MLAIGLYNTYDPKRIHEAHLRAIARAAPVAYAFNFHLVLIGFPFE.........G.DSKEIAEEVA.KNTTIGEGGKYLIELAKSGKFHAIDFPRKGFPPQF.GEVIATTSKPSEDKVIKTIDVAKMALSGKSFLLVIGLGRHGLPKEMFKVARYHLDITdGMGVSLETCTAIGIIPAKIATLMEAl....
B3T4Q1_9ZZZZ/331-485             hv---LGLWNGYR-GGLKPPHLRALARAGALCAGFGLDLALVDFPRT.........-.ELPRLAQRVA.RESR-ADGGEWFAALVGDGRVKLFS----GVPGKWaGILVATTPRPGKPEPPEPFEG--------RLCLLLGVGSQGLPGKLLKAAKFHLELT.GHGIELETATAMGVIAERLST----l....
D5E7U5_METMS/1-174               ..MQTIGIVNTYDRIKVLDAHYRAIARAAPICRIFGFSLALFDFPFD.........M.EKDELVKYVV.EKTTIGESGAYLQQLNEEHHFFVQDLPKKGFPAHF.GKPVATTSRIDGSKRMTVMDAAEGIIHQDSYLFLVGLGRKGLPKSIIKQAPAHLDIS.SGGTSCETCTAMGAIPAYIMGIVE-gi...
Q0W266_UNCMA/1-175               ..MLTLGLYNTYDRNKVVEAHYRGIARGAPIAYAFGFNLALVGFPYD.........F.EKQELVDFVR.DNTTIGESGAYLQKLHDEKRLYVMDIPQKGFPAQF.GSLVVTSSHGDKKKAVSSREVADMMARNKPLFILIGLGRKGLPKEYFEMAPYHLDITdGKGVSFETCTAIGAIAARLYTLAEQq....
Q12W36_METBU/1-174               ..MLTLGLINTYDKIKVLDAHYRAIARAAPICYAYGLTLCLFDFPFK.........M.TPEELVEYIM.DKTTIGGSGKYLKALHENNRLFIFDLPKKGFQSQF.GTAVVTTSMPEDKFTVTPEDIAGGMMRNRSYLLLIGLGRKGLPKKLYSLTDHHLDIT.CDGISLETCTAMGIIPAYIMGIVNTr....
C7P6V0_METFA/6-169               ..RMTLILYNSYDKTRWHEAHKRAIARAAPICYAFDCNLAIMDFPCE.........-.----MEDILN.IKTTIGNSGEYLEKLIEKNRFFIVD----KFLPQF.GIPIASTSKPDEKKAITPLDTA-YLLKKKPVGIYVGLGRHGLPKDIVESCSYHLDIT.EKRVSLETCTAIGCIPAVIYTYTKYl....
Q5JDR7_PYRKO/3-176               .t-LTLALYNTYDTKRLHEAHLRAIARAAPIAYAYGFHLALVGFPLD.........G.KPMEIAEEVS.RHTTIGDGGKYLQELAKANKFHLLEFPKKGFPPQF.GTPVATTRKPWPEKEITPLDLTREALSGRSFLLLIGLGRHGLPEEIFKIARYHMDVT.GKRTSLETCTAMGAIGARIATYMEAl....
A6UT28_META3/6-169               ..RMTMILYNSYDKNKWHEAHKRAIARAASICYAFECNLAIMNFPCK.........R.-----EDITS.IETTIGSSGKYLNELIEKNRFMIVD----KYQPQF.GVPIITTSKPEPKKAISPKEVAQSLL-KKSCGIYVGLGRHGLPKNILKSGELHLDIT.EKGISLETCTAISAIPSTIYTHSK-yl...
Q8TU36_METAC/5-178               ..MLTLGIVNTYDKIKVLDAHYRAIARAAPICHAFGFHLALYDFPFK.........M.TAEELVAFVM.EKTTIGESGSYLRVLYEKNHLSVADLPKKGFPSQF.GDTVITTSKPDPKRKVLPVEIAEEALRNHSFLFLVGLGHKGLPKELFGRGKYHLDIT.SKGLSLETCTAIGAIPAHLSGLMG-nl...
O29840_ARCFU/1-165               ..MISICLVNTYDKLKKHEIHLRSIARAAPLCYAFNFHLALLDFPFW.........R.SEKEVAEEVA.NYTTIGEGGKYLLYLAESGKLHLID----KIPAHF.GEVVATTSKPDPDKVVNPDTLAAF----KSATFLIGLGRRGLPREMLKSAKYHLDVT.RKGVSLETCSAIGAI-AMLLA----vkvvg
#=GC seq_cons                    ..MlTLuLYNTYD+pKlHEAHhRAIARAAPICYAFsFpLALhsFPhc.........t.p..-ls-hls.pcTTIG-uGcYLtcLh-pN+FallDhP.hGFPsQF.GpsVATTSKP-ccKtIoPh-lAchhL+t+ShhlLlGLGRHGLPK-lhKhu+YHLDIT.GKslSLETCTAIGuIPApItTlhc.h....
//