GenomeNet

Database: Pfam
Entry: PF08204
LinkDB: PF08204
Original site: PF08204 
#=GF ID   V-set_CD47
#=GF AC   PF08204.8
#=GF DE   CD47 immunoglobulin-like domain
#=GF AU   Mifsud W, Bateman A
#=GF SE   Pfam-B_2739 (release 7.5)
#=GF GA   20.60 20.60;
#=GF TC   20.60 20.60;
#=GF NC   20.50 20.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   12124426
#=GF RT   Expression of CD47/integrin-associated protein induces death of
#=GF RT   cultured cerebral cortical neurons. 
#=GF RA   Koshimizu H, Araki T, Takai S, Yokomaku D, Ishikawa Y, Kubota M,
#=GF RA   Sano S, Hatanaka H, Yamada M; 
#=GF RL   J Neurochem 2002;82:249-257.
#=GF RN   [2]
#=GF RM   8794870
#=GF RT   Integrin-associated protein immunoglobulin domain is necessary
#=GF RT   for efficient vitronectin bead binding. 
#=GF RA   Lindberg FP, Gresham HD, Reinhold MI, Brown EJ; 
#=GF RL   J Cell Biol 1996;134:1313-1322.
#=GF DR   INTERPRO; IPR013270;
#=GF CC   This family represents the CD47 leukocyte antigen V-set like Ig
#=GF CC   domain [1,2].
#=GF SQ   85
#=GS A0A096NQZ6_PAPAN/8-142    AC A0A096NQZ6.1
#=GS G7NZR3_MACFA/1-127        AC G7NZR3.1
#=GS H0VBJ7_CAVPO/8-140        AC H0VBJ7.1
#=GS Q08FL4_DPV83/15-127       AC Q08FL4.1
#=GS F1NSJ5_CHICK/8-140        AC F1NSJ5.2
#=GS Q8V3H1_SWPV1/6-113        AC Q8V3H1.1
#=GS M3YET2_MUSPF/1-125        AC M3YET2.1
#=GS F1SL37_PIG/1-125          AC F1SL37.2
#=GS CD47_PONAB/8-142          AC Q5REL0.1
#=GS H2P9U0_PONAB/8-142        AC H2P9U0.2
#=GS H0WL00_OTOGA/3-135        AC H0WL00.1
#=GS Q6XFR0_CHICK/8-141        AC Q6XFR0.1
#=GS F7F5Z4_MACMU/8-142        AC F7F5Z4.1
#=GS Q6XFR1_CHICK/8-140        AC Q6XFR1.1
#=GS U3ID47_ANAPL/9-141        AC U3ID47.1
#=GS G3Q4M7_GASAC/9-109        AC G3Q4M7.1
#=GS F7F5Z8_MACMU/8-142        AC F7F5Z8.1
#=GS G1LYV2_AILME/2-74         AC G1LYV2.1
#=GS CD47_HUMAN/8-142          AC Q08722.1
#=GS CD47_HUMAN/8-142          DR PDB; 2VSC B; 1-115;
#=GS CD47_HUMAN/8-142          DR PDB; 4KJY C; 1-114;
#=GS CD47_HUMAN/8-142          DR PDB; 4CMM B; 1-118;
#=GS CD47_HUMAN/8-142          DR PDB; 2JJS D; 1-116;
#=GS CD47_HUMAN/8-142          DR PDB; 4KJY A; 1-114;
#=GS CD47_HUMAN/8-142          DR PDB; 2VSC A; 1-115;
#=GS CD47_HUMAN/8-142          DR PDB; 2VSC D; 1-116;
#=GS CD47_HUMAN/8-142          DR PDB; 2JJS C; 1-116;
#=GS CD47_HUMAN/8-142          DR PDB; 2JJT C; 1-115;
#=GS CD47_HUMAN/8-142          DR PDB; 2VSC C; 1-115;
#=GS CD47_HUMAN/8-142          DR PDB; 2JJT D; 1-115;
#=GS G1PH34_MYOLU/9-142        AC G1PH34.1
#=GS G1L3T4_AILME/8-141        AC G1L3T4.1
#=GS G1TS80_RABIT/8-140        AC G1TS80.2
#=GS A38_VAR67/2-124           AC P33853.1
#=GS CD47_BOVIN/8-140          AC Q9N0K1.1
#=GS M3WBM1_FELCA/1-124        AC M3WBM1.1
#=GS W5LMQ2_ASTMX/20-117       AC W5LMQ2.1
#=GS D3Z187_MOUSE/1-41         AC D3Z187.1
#=GS A0A091E6Q2_FUKDA/1-41     AC A0A091E6Q2.1
#=GS J9P735_CANFA/8-140        AC J9P735.1
#=GS H0ZVL5_TAEGU/1-126        AC H0ZVL5.1
#=GS I3NDM6_SPETR/8-140        AC I3NDM6.1
#=GS Q6TUP1_YMTV5/1-98         AC Q6TUP1.1
#=GS F7B173_HORSE/1-89         AC F7B173.1
#=GS G3QXE4_GORGO/8-142        AC G3QXE4.1
#=GS CD47_MOUSE/8-140          AC Q61735.2
#=GS F6ZW32_MONDO/6-138        AC F6ZW32.2
#=GS G5CA37_HETGA/1-125        AC G5CA37.1
#=GS R4GAV1_ANOCA/9-142        AC R4GAV1.1
#=GS F1P6D7_CANFA/8-140        AC F1P6D7.2
#=GS CD47_PIG/8-140            AC Q9GKE8.1
#=GS I3JAZ3_ORENI/14-142       AC I3JAZ3.1
#=GS F7A802_MACMU/8-142        AC F7A802.1
#=GS A0A0D9R1W9_CHLSB/8-142    AC A0A0D9R1W9.1
#=GS G1SKT7_RABIT/8-140        AC G1SKT7.2
#=GS E7F6J1_DANRE/16-124       AC E7F6J1.1
#=GS I3NFP1_SPETR/8-140        AC I3NFP1.1
#=GS L5L524_PTEAL/1-41         AC L5L524.1
#=GS A0A0G2JTH4_RAT/8-137      AC A0A0G2JTH4.1
#=GS I3MLK0_SPETR/4-135        AC I3MLK0.1
#=GS W5QC22_SHEEP/1-128        AC W5QC22.1
#=GS A0A087XK36_POEFO/204-301  AC A0A087XK36.2
#=GS A0A096MDN3_POEFO/210-307  AC A0A096MDN3.1
#=GS CD47_RAT/8-140            AC P97829.1
#=GS Q9Q8V0_RFVKA/10-120       AC Q9Q8V0.1
#=GS A0A091E6Q8_FUKDA/1-125    AC A0A091E6Q8.1
#=GS F1MUL0_BOVIN/8-140        AC F1MUL0.2
#=GS F6QKT4_ORNAN/9-140        AC F6QKT4.1
#=GS F7A7Y5_MACMU/8-142        AC F7A7Y5.1
#=GS F7I1Q3_CALJA/8-142        AC F7I1Q3.1
#=GS W5MSG0_LEPOC/10-133       AC W5MSG0.1
#=GS H2P9U1_PONAB/8-142        AC H2P9U1.1
#=GS I3K8H7_ORENI/227-334      AC I3K8H7.1
#=GS U3JVE9_FICAL/2-129        AC U3JVE9.1
#=GS G3HDA3_CRIGR/1-84         AC G3HDA3.1
#=GS I3K8H7_ORENI/2-123        AC I3K8H7.1
#=GS A38_VACCW/2-124           AC P24763.1
#=GS F6ZW27_MONDO/8-140        AC F6ZW27.2
#=GS L5MJA6_MYODS/11-136       AC L5MJA6.1
#=GS G3RW86_GORGO/3-137        AC G3RW86.1
#=GS L8Y0C4_TUPCH/1-39         AC L8Y0C4.1
#=GS F1MA83_RAT/8-142          AC F1MA83.3
#=GS G3TCK8_LOXAF/4-136        AC G3TCK8.1
#=GS A0A0A0MY37_RAT/8-140      AC A0A0A0MY37.1
#=GS Q9Q8H3_MYXVL/1-111        AC Q9Q8H3.1
#=GS G3WG71_SARHA/1-125        AC G3WG71.1
#=GS H0ZTR7_TAEGU/8-141        AC H0ZTR7.1
#=GS F7I1R1_CALJA/8-142        AC F7I1R1.1
#=GS H2QN21_PANTR/1-127        AC H2QN21.1
#=GS G1NNJ4_MELGA/8-140        AC G1NNJ4.2
#=GS V8NSR6_OPHHA/9-143        AC V8NSR6.1
#=GS F7F5Y9_MACMU/8-142        AC F7F5Y9.1
#=GS G1QTZ5_NOMLE/8-142        AC G1QTZ5.1
#=GS Q08DW0_BOVIN/8-140        AC Q08DW0.1
#=GS A0A087X762_POEFO/8-138    AC A0A087X762.2
#=GS L5LHS8_MYODS/1-84         AC L5LHS8.1
A0A096NQZ6_PAPAN/8-142               .............................................................................LLLGSACCGS.AQLLFNKTKSVE..FTFC..ND..T.VIIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....aPAN.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
G7NZR3_MACFA/1-127                   ............................................................................g---------S.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....aPAN.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
H0VBJ7_CAVPO/8-140                   ........................................................................lkkyf-----SFPGS.AQLLLNKTKLVE..YTIC..NK..T.VVIPCF..VI.N.VGAQ..ST....KEMF.VKW.....K...F......N....G......T....Y.......I...F...N....Y......DG..S..A....N..NST.....aKKN.F....S...S....AKIe.......vSKLL.K.G..D.A.S.L.Q.M.S..K..E.D.VK..V.GNYTCEV.TELSR..EG...E...T.VVEVKYRMVSWFSPNEN......................
Q08FL4_DPV83/15-127                  ...........................................................................fi--LTIFICFYcSEQTLTTVNSVM..YTSC..NK..T.ILLTCN..LD.K.LIYD..NI....SNID.IRW.....K...V......D....G......N....S.......I...F...L....V......NK..T..Y....Y..NL-......---.-....-...-....---.........----.-.-..-.S.S.L.L.F.N..F..S.T.SL..T.GNYTCEA.ASKFN..KI...K...N.IIMLQY-TSEWFTKEE-i.....................
F1NSJ5_CHICK/8-140                   ............................................................................a-LLAVLGAGS.TQLVFNAVDFVE..KYAC..ND..T.VVLPCI..VT.N.LKEN..ND....SSMH.VSW.....K...R......Q....G......Q....V.......I...F...S....F......NG..P..E....Q..RIY.....rHES.V....P...S....ANFl......skADLF.K.G..I.A.S.L.R.L.K..N..A.E.AP..D.GNYSCEV.TELNR..EG...E...T.KMKLRTHMVDSC-----deek..................
Q8V3H1_SWPV1/6-113                   ............................................................................l-LLLCYYPVLsKFIFFTNE----..FTIC..ND..T.VSVHCD..IS.S.LIYS..NI....SDIH.VNW.....S...L......N....N......H....N.......I...N...H....K......HT..I..H....N..ITT......---.-....-...-....---.........----.-.-..-.-.-.L.L.F.N..F..S.K.DI..N.GNYTCEA.SGKFN..KI...I...H.TTYVSY-TVKWFNHEE-r.....................
M3YET2_MUSPF/1-125                   ............................................................................g---------S.AQLIFNITKSVE..YTAC..NE..S.VIIPCF..VN.N.VEAT..NI....NEMY.VKW.....K...L......K....G......K....D.......I...F...T....F......NG..A..L....Q..KTT.....hGDK.F....K...S....TKIi.......pQKLL.T.G..I.A.S.L.E.M.D..K..E.E.AV..V.GNYTCEV.TELSR..EG...E...T.IIELKYRIVSWFSPNEN......................
F1SL37_PIG/1-125                     ............................................................................g---------S.AQLIFNITKSVE..FTVC..NT..T.VTIPCF..VN.N.MEAK..NI....SELY.VKW.....K...F......K....G......K....D.......I...F...I....F......DG..A..Q....H..ISK.....pSEA.F....P...S....SKIs.......pSELL.H.G..I.A.S.L.K.M.D..K..R.D.AV..I.GNYTCEV.TELSR..EG...E...T.IIELKRRFVSWFSPNEN......................
CD47_PONAB/8-142                     .............................................................................LLLGSACCGS.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....vPTD.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
H2P9U0_PONAB/8-142                   .............................................................................LLLGSACCGS.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....vPTD.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
H0WL00_OTOGA/3-135                   ...........................................................................tv--LSASCARS.AQLLFNKTKSVE..YTVC..NE..T.ISIPCF..VI.N.MEAE..NT....NEVY.VKW.....K...F......K....G......K....D.......I...Y...T....F......DG..S..D....N..RST.....hDSA.F....K...T....SGIk.......iSELL.K.G..D.A.T.L.M.M.H..Q..S.N.AV..P.GNYTCEV.TVLSR..EG...E...T.TIEVKYRIVSWFSPNEN......................
Q6XFR0_CHICK/8-141                   ............................................................................a-LLAVLGAGS.TQLVFNAVDFVE..KYAC..ND..T.VVLPCI..VT.N.LKEN..ND....SSMH.VSW.....K...R......Q....G......Q....V.......I...F...S....F......NG..P..E....Q..RIY.....rHES.V....P...S....ANFl......skADLF.K.G..I.A.S.L.R.L.K..N..A.E.AP..D.GNYSCEV.TELNR..EG...E...T.KMKLRTHMERQFDFIQ-s.....................
F7F5Z4_MACMU/8-142                   .............................................................................LLLGSACCGS.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....aPAN.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
Q6XFR1_CHICK/8-140                   ............................................................................a-LLAVLGAGS.TQLVFNAVDFVE..KYAC..ND..T.VVLPCI..VT.N.LKEN..ND....SSMH.VSW.....K...R......Q....G......Q....V.......I...F...S....F......NG..P..E....Q..RIY.....rHES.V....P...S....ANFl......skADLF.K.G..I.A.S.L.R.L.K..N..A.E.AP..D.GNYSCEV.TELNR..EG...E...T.KMKLRTHMVDSC-----deek..................
U3ID47_ANAPL/9-141                   .......................................................................lisgta-------SGS.AQLVFSPVDFVE..RDAC..NT..T.VVLPCH..VV.N.LKEH..ND....SNMF.VAW.....K...K......Q....G......I....V.......L...F...S....F......DG..A..Q....Q..RVY.....rHET.V....P...S....ANLl......sqQDLS.K.G..T.A.S.L.K.L.K..S..S.E.AE..D.GNYSCEV.TELNR..EG...E...T.KVDLRTVTGRQFDFME-s.....................
G3Q4M7_GASAC/9-109                   .........................................................................vtvl----LLAAVS.PLLNVTGASTVK.iLAVV..GQ..T.VILPCR..K-.Q.VREE..NV....--LH.VEW.....K...K......D....N......D....T.......A...F...V....Y......KD..G..C....E..AFGd....kSDA.F...lY...R....TQLi.......lQELK.D.G..N.M.S.L.R.L.S..D..-.-.--..-.-------.-----..--...-...-.-----------------vravrc................
F7F5Z8_MACMU/8-142                   .............................................................................LLLGSACCGS.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....aPAN.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
G1LYV2_AILME/2-74                    ......................................................ilrtkerstkkykeckpkmwrsi----------.------------..----..--..-.------..--.-.----..--....----.---.....-...-......-....-......-....-.......-...-...-....-......--..-..-....-..---......---.-....-...-....---.........-IIQ.K.G..N.A.L.L.I.Q.E..V..Q.E.ED..G.GNYTCEL.KYEGK..LI...R...R.TTELKV-TEERVS----ktks..................
CD47_HUMAN/8-142                     .............................................................................LLLGSACCGS.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....vPTD.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
#=GR CD47_HUMAN/8-142          SS    .............................................................................BE-GGGGGGT.--EEEEHHHHHT..EEEE..EE..T.EEEEEE..EE.-.XXXX..XX....XXXX.XXX.....X...X......X....X......X....X.......X...X...X....X......XX..X..X....X..XXX.....XXXX.X....X...X....XXXX.......XXXXX.X.X..X.X.X.X.X.X.X..X..X.X.XXXXX.XXXXXXX.XXXXX..XX...X...X.XXXXXXXXXXXXXXXXX......................
G1PH34_MYOLU/9-142                   ............................................................................c-FLVSMKCGSsAQLIFNITKFAE..YTIC..NK..T.VVIPCL..VN.N.VGAQ..SL....KEMF.VKW.....K...F......R....D......K....Y.......I...F...F....Y......DG..D..K....N..ESS.....pNSN.F....S...S....AFIv.......pEALL.S.G..I.A.S.L.K.M.D..K..S.D.AV..P.GNYTCEV.TELTR..EG...E...T.IVELKYRVVSWFSPNEN......................
G1L3T4_AILME/8-141                   ...........................................................................ll--CSCTICLSsAQLIFNITKSVE..YTAC..NE..S.VIIPCF..VN.N.VEAT..NI....NEMY.VKW.....K...L......K....G......K....D.......I...F...T....F......NG..A..L....Q..KTT.....hGDN.F....K...S....TKIi.......pQKLL.T.G..I.A.S.L.E.M.D..K..A.E.AV..V.GNYTCEV.TELSR..EG...E...T.IIELKYRIVSWFSPNEN......................
G1TS80_RABIT/8-140                   .............................................................................LLLGSAGYGS.SQLLFNKMKYVE..YTRC..NK..T.VVIPCC..AI.N.MEAE..KI....SELF.IKW.....R...Y......K....G......N....V.......I...L...T....F......DG..L..L....N..MTT.....kFNN.F....T...T....AKId.......vSKLL.K.G..D.A.S.L.E.M.D..M..S.D.AL..L.GNYTCEI.TELSR..EG...Q...T.TVELKHRTDSWFSSNE-i.....................
A38_VAR67/2-124                      ............................................................................l-RVRILLIYLcTFVVITSTKTIE..YTAC..ND..T.IIIPCT..ID.N.----..--....PTKY.IRW.....K...L......D....N......H....N.......I...L...T....Y......NK..T..S....K..TII.....lSKW.H....T...S....AKL.........HSLS.D.N..D.V.S.L.I.I.K..Y..K.D.IL..P.GTYTCED.---NT..GI...K...S.TVKLVQRHTNWFNDH--ht....................
CD47_BOVIN/8-140                     .............................................................................LLLGSVRCGS.AQLIFNAIKSVE..YTLC..NQ..T.VVIPCF..VN.N.VETK..NI....TELY.VRW.....K...F......K....G......E....N.......I...F...I....F......DG..S..Q....R..MSK.....pSSN.F....S...S....AEIa.......pSELL.R.G..I.A.S.L.K.M.A..K..S.D.AV..L.GNYTCEV.TELSR..EG...E...T.IIELKYRVVSWFSPNEN......................
M3WBM1_FELCA/1-124                   ............................................................................s----------.AQLIFNITRSVE..YTAC..NE..T.VIIPCY..VN.N.VEAT..NI....NEMY.VKW.....K...F......R....G......K....D.......I...F...T....F......DG..A..V....E..KTT.....rDNK.F....K...S....TKIi.......pQKLL.N.G..I.A.S.L.E.M.N..K..E.E.AV..V.GNYTCEV.TELSR..EG...E...T.IIELKYRIVSWFSPNEN......................
W5LMQ2_ASTMX/20-117                  ..........................................................................qsg----------.------------..----..-S..V.VILPCY..LH.-.-PER..SA....VEMT.VRW.....F...R......G....T......E....C.......I...C...L....Y......KD..G..R....M..TVG.....rGYE.G....R...I....SLF........sQELE.K.G..N.V.S.L.I.I.R..D..Y.S.WT..G.DDYLCQV.SNKET..TA...E...F.TVGL-------------ddpte.................
D3Z187_MOUSE/1-41                    .............................................................................----------.------------..----..--..-.------..--.-.----..--....----.---.....-...-......-....-......-....-.......-...-...-....-......--..-..-....-..---......---.-....-...-....---.........----.-.-..-.-.-.-.-.M.D..K..R.D.AM..V.GNYTCEV.TELSR..EG...K...T.VIELKNRTVSWFSPNEK......................
A0A091E6Q2_FUKDA/1-41                .............................................................................----------.------------..----..--..-.------..--.-.----..--....----.---.....-...-......-....-......-....-.......-...-...-....-......--..-..-....-..---......---.-....-...-....---.........----.-.-..-.-.-.-.-.M.D..K..A.D.AK..L.GNYTCEI.TELTR..EG...E...T.VVELKYHSVSWFSSNE-c.....................
J9P735_CANFA/8-140                   .............................................................................LLLGSASCGS.AQLIFNITKSVE..YTAC..NE..S.VIIPCF..VN.N.VEAT..NI....NEMY.VKW.....K...F......R....G......K....D.......I...F...T....F......DG..A..V....Q..KTT.....hGDK.F....K...S....TKIv.......pQKLL.N.G..I.A.S.L.E.M.S..K..E.E.AV..V.GNYTCEV.TELSR..EG...E...T.IIELKYRIVSWFSPNEN......................
H0ZVL5_TAEGU/1-126                   ............................................................................g---------S.AQLSLYGTSVVE..KNDC..NK..T.VVLPCY..VT.D.LKQN..NE....NVMS.VTW.....K...R......Q....G......V....T.......I...F...F....Y......HG..G..N....K..NFN.....iDPS.F....S...S....ARFl......skAELI.K.G..V.A.S.L.V.I.D..S..A.Q.AT..V.GNYSCKV.TESNS..EG...E...I.KMELKSSSGSWFLL---mer...................
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G3QXE4_GORGO/8-142                   ............................................................................l-LLGSAXXXS.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....vPTD.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
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G5CA37_HETGA/1-125                   ............................................................................g---------S.AQLLLNKTKFVE..YTIC..NE..T.VVIPCF..VI.N.VGAQ..ST....KEVF.VKW.....K...F......N....G......T....Y.......I...F...I....Y......DG..N..K....N..IST.....aNLN.F....S...S....AKIa.......vSKLL.K.G..D.A.S.L.K.M.S..K..D.D.VK..V.GNYTCEV.TELTR..EG...E...T.IIEVKYRMVSWFSPNEN......................
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I3JAZ3_ORENI/14-142                  ................................................................lvalavivglsvy----------.VRRLLNKVPQVM..ADSG..VE..T.VYLLCK..TT.A.HLPQ..DA....---K.VEW.....K...K......S....D......R....K.......V...H...V....Y......EN..G..S....D..QPG.....eQHQ.Yy..rG...R....TKL........nEDLL.KsG..D.L.S.L.S.L.K..Y..P.T.E-..G.GIYTCTV.YSRKGniLL...K...R.KVELKV-----------rgqc..................
F7A802_MACMU/8-142                   .............................................................................LLLGSACCGS.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....aPAN.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
A0A0D9R1W9_CHLSB/8-142               .............................................................................LLLGSACCGS.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..P..L....N..KST.....aPAN.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.L.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
G1SKT7_RABIT/8-140                   .............................................................................LLLGSACCGS.AQLIFNKTKSVE..FTFC..NE..T.VVIPCF..VK.N.VEAV..GT....MEMY.VKW.....R...F......K....G......K....Y.......I...F...I....Y......DG..G..Q....N..KST.....aEND.F....S...S....AKIa.......vSELL.K.G..D.A.S.L.K.M.D..K..R.D.AV..L.GNYTCEV.TELSR..EG...E...T.TVELKYRVVSWFSPNEN......................
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A0A0G2JTH4_RAT/8-137                 .............................................................................LLLGSCCCGS.AQLLLSKVKSVE..FTSC..ND..T.VVIPCK..VL.N.VEAQ..ST....DEMF.VKW.....K...L......N....K......S....Y.......I...F...I....Y......DG..N..K....N..STT.....rEQN.F....T...S....AKIs.......vSDLL.K.G..I.A.S.L.T.M.D..T..H.E.AV..V.GNYTCEV.TELSR..EG...K...T.VIELKN-----------rpafntdq..............
I3MLK0_SPETR/4-135                   .........................................................................sfsf-----SFPGS.AQLLFNKTKSVE..FTFC..NE..T.VVIPCF..VI.N.VGAQ..NT....NEMY.VKW.....K...F......K....G......K....Y.......I...F...I....Y......DG..G..Q....D..NAT.....mDSN.F....S...S....AKIa.......vSELL.K.G..D.A.S.L.K.M.D..K..R.D.AK..V.GNYTCEV.TELTR..EG...E...T.VIELKYRVVSWFSPNEN......................
W5QC22_SHEEP/1-128                   ..........................................................................mer--------GS.AQLIFNVIKSVE..YTLC..NQ..T.VVIPCF..VN.N.VETK..NI....TELY.VRW.....K...F......K....G......E....N.......I...F...I....F......DG..S..K....R..MSK.....pSSN.F....S...S....AKIt.......pPELL.R.G..I.A.S.L.K.M.D..K..S.D.AV..V.GNYTCEV.TELSR..EG...E...T.IIELKYRVVSWFSPNEN......................
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CD47_RAT/8-140                       .............................................................................LLLGSCCCGS.AQLLLSKVKSVE..FTSC..ND..T.VVIPCK..VL.N.VEAQ..ST....DEMF.VKW.....K...L......N....K......S....Y.......I...F...I....Y......DG..N..K....N..STT.....rEQN.F....T...S....AKIs.......vSDLL.K.G..I.A.S.L.T.M.D..T..H.E.AV..V.GNYTCEV.TELSR..EG...K...T.VIELKNRPVSWFSTNEK......................
Q9Q8V0_RFVKA/10-120                  ............................................................................a-HVGLLLVVF.VHLTVGNKVTVM.pYTVC..NT..T.ITLECN..LD.E.LIYK..DI....NSIH.VKW.....L...F......Y....T......M....D.......D...T...I....S......NI..T..N....G..SF-......---.-....-...-....---.........----.-.-..-.-.-.I.K.F.D..F..A.K.NL..S.GNYTCEA.YSDLN..SV...K...N.VIALNL-VHQWFSREE-l.....................
A0A091E6Q8_FUKDA/1-125               ............................................................................g---------S.AQLLLNKTKLVE..YTIC..NE..T.VVIPCF..VI.N.VGAQ..ST....KEMY.VKW.....K...F......N....G......T....Y.......I...F...I....Y......DG..N..K....N..IST.....aNLN.F....S...S....AKIa.......vSKLL.K.G..D.A.S.L.K.M.S..K..D.D.VK..V.GNYTCEV.TELSR..EG...E...T.IIEVKYRMVSWFSPNEN......................
F1MUL0_BOVIN/8-140                   .............................................................................LLLGSVRCGS.AQLIFNAIKSVE..YTLC..NQ..T.VVIPCF..VN.N.VETK..NI....TELY.VRW.....K...F......K....G......E....N.......I...F...I....F......DG..S..Q....R..MSK.....pSSN.F....S...S....AEIa.......pSELL.R.G..I.A.S.L.K.M.A..K..S.D.AV..L.GNYTCEV.TELSR..EG...E...T.IIELKYRVVSWFSPNEN......................
F6QKT4_ORNAN/9-140                   ........................................................................scffa------LPGS.AQLLFDSPRLVE..KNAC..NH..S.VLLPCS..VT.N.IELN..NI....RAMF.VRW.....K...Y......K....G......R....D.......I...Y...T....F......DG..F..Q....D..KVT.....iSND.F....Q...S....ASIf.......vPDIL.S.G..N.S.S.L.R.L.S..D..D.D.AV..L.GNYTCEV.TEANR..EG...E...I.IVELRYHVVSWFNPKEN......................
F7A7Y5_MACMU/8-142                   .............................................................................LLLGSACCGS.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....aPAN.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
F7I1Q3_CALJA/8-142                   .............................................................................LLLGSACCGS.AQLLFNKTKSVE..FTFC..NE..T.VVIPCF..VT.N.MEAQ..NT....TEIY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..RST.....vPSG.F....N...S....AKIe.......vSRLL.K.G..D.A.S.L.K.L.D..K..S.D.ATshT.GNYTCEV.TELTR..EG...E...T.IVELKYRVVSWFSPNEN......................
W5MSG0_LEPOC/10-133                  ..........................................................................lls--LMLLHYGQ.AQLIITKE-AQN..GTYC..SA..A.-LLKCI..VT.N.LRQN..KI....QNMV.LIW.....K...L......N....N......E....E.......I...Y...G....F......NG..E..D....G..KERk....lDSV.G....P...Q....VDL.........KALA.H.G..N.A.S.I.W.L.K..S..P.K.--..P.GNYTCYV.LEGSS..EG...S...G.VFKF-------------tevwdnyt..............
H2P9U1_PONAB/8-142                   .............................................................................LLLGSACCGS.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....vPTD.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
I3K8H7_ORENI/227-334                 ....................................................................qvevdseve----------.------------..----..--..S.VQLPCK..TT.-.IHLP..--....EDAK.VEW.....M...D......N....R......K....V.......H...V...Y....E......NG..S..D....Q..PEE.....qHQV.Y...rN...R....TKM........nEDLL.KtG..D.L.S.L.T.L.K..Y..P.T.DG.dN.RTYTCTV.YSREGniLL...K...K.QVELKV-----------rgqc..................
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G3HDA3_CRIGR/1-84                    .............................................................................----------.------------..----..--..-.------..--.-.----..--....--MY.VKW.....K...L......N....K......T....Y.......I...F...I....Y......DG..S..K....N..NST.....vETN.F....T...S....AKIs.......vSDLL.K.G..D.A.S.L.K.M.E..R..Q.Q.AV..L.GNYTCEV.TELSR..EG...K...T.VIELKYRMD--------sipdq.................
I3K8H7_ORENI/2-123                   ......................................................................lcfvvis----------.-------VPQVE..VDSG..TE..S.VQLPCK..T-.T.LHLP..--....EDAK.VEW.....K...D......S....Gy....kK....V.......H...V...Y....K......NG..S..D....Q..PEE.....qHQV.Y...rD...R....TKM........nEDLL.KtG..D.L.S.L.T.L.K..H..P.T.DG.eG.GIYTCTV.YSRER..KIl.mK...K.EVVLQVR----------vrqvev................
A38_VACCW/2-124                      ...........................................................................sr--VRISLIYLcTFMIITSTKTIE..YTAC..NN..T.IIIPCT..ID.N.----..--....PTKY.IRW.....K...L......D....N......H....D.......I...L...T....Y......NK..T..S....K..TTI.....lSKW.H....T...S....ARL.........HSLS.D.S..D.V.S.L.I.I.E..Y..K.D.IL..P.GTYTCED.---NT..GI...K...S.TVKLVQRHTNWFNDYQ-t.....................
F6ZW27_MONDO/8-140                   ............................................................................l-LLGTVCGGS.AQLTFNSTRIVE..KTIC..NE..T.VILPCI..VS.N.LELR..KL....KAMY.VKW.....K...H......K....G......K....E.......I...F...T....F......DG..V..D....N..KFN.....sSDD.F....K...S....ATIa.......fSHLT.E.G..N.A.S.L.Q.L.K..A..S.D.AV..P.GNYTCEV.TESNR..EG...E...I.IVELRYHMVSWFHPKEN......................
L5MJA6_MYODS/11-136                  ........................................................................hsyqk------LASS.AQLLFATIKSVE..YTND..NK..T.ILIPCL..VT.N.GGAQ..SL....RELF.VKW.....K...F......G....N......K....D.......I...F...F....Y......DG..D..K....N..ESS.....pNSD.F....S...S....AYIi.......pNALL.T.G..N.A.S.L.M.M.D..K..R.H.AV..P.GNYTCEV.TELTR..EG...E...T.TIELKYV----------avig..................
G3RW86_GORGO/3-137                   ..........................................................................imm---PSSCARS.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....vPTD.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
L8Y0C4_TUPCH/1-39                    .............................................................................----------.------------..----..--..-.------..--.-.----..--....----.---.....-...-......-....-......-....-.......-...-...-....-......--..-..-....-..---......---.-....-...-....---.........----.-.-..-.-.-.-.-.M.A..K..S.D.AT..V.GNYSCEV.TELSR..EA...E...T.TIELKYRVVKL------icll..................
F1MA83_RAT/8-142                     .............................................................................LLLGSFHCGL.AQLLFKNISSVK..IDHC..KN..I.VLIPCY..VS.N.LEAE..NI....NELF.LKW.....K...Fg....rN....S......D....I.......I...F...V....F......DG..Y..A....N..KSA.....aFYK.F....S...S....AHIf.......pSEFL.K.G..N.A.S.L.N.V.A..K..E.E.VK..N.GKYTCEV.TELSR..EG...Q...Q.TVDLQYTDGSLFTLKE-h.....................
G3TCK8_LOXAF/4-136                   ...........................................................................ii--LGICSICS.AQITFNVIKSVE..YTVC..NE..T.LVIPCF..AT.N.VETK..QL....AELY.VKW.....K...F......K....G......K....D.......I...F...I....F......DG..S..R....N..QST.....pSSN.F....T...S....AEIt.......pEELL.R.G..I.A.S.L.K.M.K..K..K.D.AV..P.GNYTCEV.TELSR..EG...E...T.TIQLKYRVVSWFFQKEN......................
A0A0A0MY37_RAT/8-140                 .............................................................................LLLGSCCCGS.AQLLLSKVKSVE..FTSC..ND..T.VVIPCK..VL.N.VEAQ..ST....DEMF.VKW.....K...L......N....K......S....Y.......I...F...I....Y......DG..N..K....N..STT.....rEQN.F....T...S....AKIs.......vSDLL.K.G..I.A.S.L.T.M.D..T..H.E.AV..V.GNYTCEV.TELSR..EG...K...T.VIELKNRPVSWFSTNEK......................
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G3WG71_SARHA/1-125                   ............................................................................g---------S.AQLTFNSTRFVE..ETIC..NE..T.VVLPCI..VN.N.LEIR..KI....EVMY.VKW.....K...H......K....G......K....E.......I...F...T....F......SG..E..Q....K..KHN.....aSDN.F....K...S....ATIp.......fSLLV.E.G..N.A.S.L.L.M.K..K..S.D.AI..P.GNYSCEV.TESNR..EG...E...T.TVELKYHVVSWFYPKEN......................
H0ZTR7_TAEGU/8-141                   ............................................................................v-LLAALRAGS.AQLSLYGTSVVE..KNDC..NK..T.VVLPCY..VT.D.LKQN..NE....NVMS.VTW.....K...R......Q....G......V....T.......I...F...F....Y......HG..G..N....K..NFN.....iDPS.F....S...S....ARFl......skAELI.K.G..V.A.S.L.V.I.D..S..A.Q.AT..V.GNYSCKV.TESNS..EG...E...I.KMELKSSSGSWFLL---mer...................
F7I1R1_CALJA/8-142                   .............................................................................LLLGSACCGS.AQLLFNKTKSVE..FTFC..NE..T.VVIPCF..VT.N.MEAQ..NT....TEIY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..RST.....vPSG.F....N...S....AKIe.......vSRLL.K.G..D.A.S.L.K.L.D..K..S.D.ATshT.GNYTCEV.TELTR..EG...E...T.IVELKYRVVSWFSPNEN......................
H2QN21_PANTR/1-127                   ............................................................................g---------S.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....vPTD.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVlhT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
G1NNJ4_MELGA/8-140                   ...........................................................................cm--LLLQWAGS.TQLMFNAVDFVE..KYAC..ND..T.VVLPCI..VI.N.LKEN..ND....SSMH.VSW.....K...R......Q....G......Q....V.......I...F...S....F......SG..P..E....Q..RIY.....rHES.V....P...S....ANFl......skMDLS.K.G..V.A.S.L.Q.L.K..N..A.E.AT..D.GNYSCEV.TELNR..EG...E...T.KMELRTHMVDSC-----deek..................
V8NSR6_OPHHA/9-143                   ............................................................................v-LLGTLGAGS.AQLSFQNVPFLE..INYC..NG.pQ.FVLPCV..VT.N.LKEN..NS....VSMF.VSW.....Q...F......Q....G......N....P.......F...F...I....Y......DG..V..S....D..NIT.....kNNS.F....H...T....AQFl......nrSMLP.Y.G..I.V.S.L.V.I.S..T..N.E.TV..L.GNYTCEV.TEVNR..EG...K...T.RFELRASSVPWFQPVE-r.....................
F7F5Y9_MACMU/8-142                   .............................................................................LLLGSACCGS.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....aPAN.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
G1QTZ5_NOMLE/8-142                   .............................................................................LLLGSACCGS.AQLLFNKTKSVE..FTFC..ND..T.VVIPCF..VT.N.MEAQ..NT....TEVY.VKW.....K...F......K....G......R....D.......I...Y...T....F......DG..A..L....N..KST.....vPTD.F....S...S....AKIe.......vSQLL.K.G..D.A.S.L.K.M.D..K..S.D.AVshT.GNYTCEV.TELTR..EG...E...T.IIELKYRVVSWFSPNEN......................
Q08DW0_BOVIN/8-140                   .............................................................................LLLGSVRCGS.AQLIFNAIKSVE..YTLC..NQ..T.VVIPCF..VN.N.VETK..NI....TELY.VRW.....K...F......K....G......E....N.......I...F...I....F......DG..S..Q....R..MSK.....pSSN.F....S...S....AEIa.......pSELL.R.G..I.A.S.L.K.M.A..K..S.D.AV..L.GNYTCEV.TELSR..EG...E...T.IIELKYRVVSWFSPNEN......................
A0A087X762_POEFO/8-138               ...................................................eltvllfllpaftltvqdsvnlevsp----------.-----------E.iFAEC..GK..P.VSLHCN..SS.S.-PQH..GL....SVKY.MEW.....S...H......G....N......M....S.......L...C...S....V......DS..E..K....T..ITK......LQR.H....Y...E....SDF........dCKYE.D.G..R.L.S.L.V.F.E..R..M.L.PL.qS.GQYRCKL.RSNKG..VA...T...E.YTK--------------vqlqefcg..............
L5LHS8_MYODS/1-84                    .............................................................................----------.------------..----..--..-.------..--.-.----..--....--MF.VKW.....K...F......R....D......K....D.......I...F...F....Y......DG..D..K....N..ESS.....pNSN.F....S...S....AYIv.......pEALL.S.G..I.A.S.L.K.M.A..K..S.H.AV..P.GNYTCEV.TELTR..EG...E...T.IVELKYRVG--------evhvs.................
#=GC SS_cons                         .............................................................................BE-GGGGGGT.--EEEEHHHHHT..EEEE..EE..T.EEEEEE..EE.-.XXXX..XX....XXXX.XXX.....X...X......X....X......X....X.......X...X...X....X......XX..X..X....X..XXX.....XXXX.X....X...X....XXXX.......XXXXX.X.X..X.X.X.X.X.X.X..X..X.X.XXXXX.XXXXXXX.XXXXX..XX...X...X.XXXXXXXXXXXXXXXXX......................
#=GC seq_cons                        ...................................................................................hhsS.AQLlFstscsVE..aThC..Nc..T.VllPCh..Vs.N.hctp..sh....s-ha.VKW.....K...a......p....G......c....s.......I...a...h....a......DG..s..p....p..pss.....hsps.F....s...S....AcI........sspLL.+.G..s.A.S.L.p.h.c..+..s.-.Al..s.GNYTCEV.TELoR..EG...E...T.llELKaRsVSWFospE.......................
//
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