GenomeNet

Database: Pfam
Entry: PF11956
LinkDB: PF11956
Original site: PF11956 
#=GF ID   KCNQC3-Ank-G_bd
#=GF AC   PF11956.7
#=GF DE   Ankyrin-G binding motif of KCNQ2-3
#=GF AU   Cooper E, Coggill P
#=GF SE   Pfam-B_10256 (release 23.0)
#=GF GA   21.20 21.20;
#=GF TC   22.20 30.80;
#=GF NC   21.10 21.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Ankyrin-G_binding_motif_of_KCNQ2-3
#=GF RN   [1]
#=GF RM   12716895
#=GF RT   Identification of a conserved ankyrin-binding motif in the
#=GF RT   family of sodium channel alpha subunits.
#=GF RA   Lemaillet G, Walker B, Lambert S;
#=GF RL   J Biol Chem. 2003;278:27333-27339.
#=GF RN   [2]
#=GF RM   16525039
#=GF RT   A common ankyrin-G-based mechanism retains KCNQ and NaV channels
#=GF RT   at electrically active domains of the axon.
#=GF RA   Pan Z, Kao T, Horvath Z, Lemos J, Sul JY, Cranstoun SD, Bennett
#=GF RA   V, Scherer SS, Cooper EC;
#=GF RL   J Neurosci. 2006;26:2599-2613.
#=GF RN   [3]
#=GF RM   16735477
#=GF RT   Polarized axonal surface expression of neuronal KCNQ channels is
#=GF RT   mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal
#=GF RT   domains.
#=GF RA   Chung HJ, Jan YN, Jan LY;
#=GF RL   Proc Natl Acad Sci U S A. 2006;103:8870-8875.
#=GF RN   [4]
#=GF RM   17311847
#=GF RT   Requirement of subunit co-assembly and ankyrin-G for M-channel
#=GF RT   localization at the axon initial segment.
#=GF RA   Rasmussen HB, Frokjaer-Jensen C, Jensen CS, Jensen HS, Jorgensen
#=GF RA   NK, Misonou H, Trimmer JS, Olesen SP, Schmitt N;
#=GF RL   J Cell Sci. 2007;120:953-963.
#=GF RN   [5]
#=GF RM   19112491
#=GF RT   Ion channel clustering at the axon initial segment and node of
#=GF RT   Ranvier evolved sequentially in early chordates.
#=GF RA   Hill AS, Nishino A, Nakajo K, Zhang G, Fineman JR, Selzer ME,
#=GF RA   Okamura Y, Cooper EC;
#=GF RL   PLoS Genet. 2008;4:e1000317.
#=GF DR   INTERPRO; IPR020969;
#=GF CC   Interactions with ankyrin-G are crucial to the localisation of
#=GF CC   voltage-gated sodium channels (VGSCs) at the axon initial
#=GF CC   segment and for neurons to initiate action potentials. This
#=GF CC   conserved 9-amino acid motif ((V/A)P(I/L)AXXE(S/D)D) is required
#=GF CC   for ankyrin-G binding and functions to localise sodium channels
#=GF CC   to a variety of 'excitable' membrane domains both inside and
#=GF CC   outside of the nervous system [1]. This motif has also been
#=GF CC   identified in the potassium channel 6TM proteins KCNQ2 and KCNQ3
#=GF CC   [2], that correspond to the M channels that exert a crucial
#=GF CC   influence over neuronal excitability. KCNQ2/KCNQ3 channels are
#=GF CC   preferentially localised to the surface of axons both at the
#=GF CC   axonal initial segment and more distally, and this axonal
#=GF CC   initial segment targeting of surface KCNQ channels is mediated
#=GF CC   by these ankyrin-G binding motifs of KCNQ2 and KCNQ3 [3]. KCNQ3
#=GF CC   is a major determinant of M channel localisation to the AIS,
#=GF CC   rather than KCNQ2 [4]. Phylogenetic analysis reveals that anchor
#=GF CC   motifs evolved sequentially in chordates (NaV channel) and jawed
#=GF CC   vertebrates (KCNQ2/3) [5].
#=GF SQ   217
#=GS M3VVS5_FELCA/641-737        AC M3VVS5.1
#=GS G3NLC0_GASAC/663-770        AC G3NLC0.1
#=GS G3SBP3_GORGO/723-823        AC G3SBP3.1
#=GS G1T2H7_RABIT/641-737        AC G1T2H7.1
#=GS KCNQ3_MOUSE/771-867         AC Q8K3F6.2
#=GS S9WNY3_CAMFR/794-889        AC S9WNY3.1
#=GS M3WAG9_FELCA/647-745        AC M3WAG9.1
#=GS M3Y9Y5_MUSPF/668-766        AC M3Y9Y5.1
#=GS A0A0P7VT09_9TELE/560-643    AC A0A0P7VT09.1
#=GS A0A091U5Q6_PHALP/349-446    AC A0A091U5Q6.1
#=GS M7BD60_CHEMY/655-755        AC M7BD60.1
#=GS W5P9E5_SHEEP/645-741        AC W5P9E5.1
#=GS F1PVZ4_CANLF/673-769        AC F1PVZ4.2
#=GS A0A0G2JFQ2_MOUSE/739-838    AC A0A0G2JFQ2.1
#=GS A0A091HPU0_CALAN/638-735    AC A0A091HPU0.1
#=GS A0A091I973_CALAN/639-735    AC A0A091I973.1
#=GS A0A091T971_NESNO/636-732    AC A0A091T971.1
#=GS A0A091N2R5_APAVI/644-741    AC A0A091N2R5.1
#=GS A0A091DFP0_FUKDA/665-760    AC A0A091DFP0.1
#=GS A0A093EJA9_TYTAL/567-663    AC A0A093EJA9.1
#=GS K7FEF1_PELSI/638-734        AC K7FEF1.1
#=GS V8NB24_OPHHA/348-441        AC V8NB24.1
#=GS F7D4R0_ORNAN/681-780        AC F7D4R0.1
#=GS G3TXG4_LOXAF/629-727        AC G3TXG4.1
#=GS A0A093LPN2_FULGA/638-734    AC A0A093LPN2.1
#=GS F1M6X3_RAT/749-848          AC F1M6X3.2
#=GS K7FZ48_PELSI/673-773        AC K7FZ48.1
#=GS W5LDV5_ASTMX/272-370        AC W5LDV5.1
#=GS G1NJK4_MELGA/645-741        AC G1NJK4.2
#=GS G1L416_AILME/668-767        AC G1L416.1
#=GS A0A096M9K0_POEFO/264-370    AC A0A096M9K0.1
#=GS F7ASD7_MACMU/746-846        AC F7ASD7.1
#=GS F6WQP9_MONDO/771-870        AC F6WQP9.2
#=GS G1N3R9_MELGA/679-776        AC G1N3R9.2
#=GS G3NFU0_GASAC/779-863        AC G3NFU0.1
#=GS B7ZBV3_MOUSE/623-722        AC B7ZBV3.1
#=GS H2LQ97_ORYLA/616-720        AC H2LQ97.1
#=GS G5C6Q1_HETGA/779-874        AC G5C6Q1.1
#=GS A0A094LEL7_9AVES/638-734    AC A0A094LEL7.1
#=GS A0A0Q3Q3K7_AMAAE/767-864    AC A0A0Q3Q3K7.1
#=GS L5JYN1_PTEAL/694-793        AC L5JYN1.1
#=GS W5N4S1_LEPOC/747-843        AC W5N4S1.1
#=GS A0A0F8AND3_LARCR/900-943    AC A0A0F8AND3.1
#=GS A0A091LCN0_CATAU/643-740    AC A0A091LCN0.1
#=GS H2L5I0_ORYLA/771-880        AC H2L5I0.1
#=GS KCNQ3_BOVIN/764-860         AC P58126.1
#=GS F7ASA7_MACMU/755-855        AC F7ASA7.1
#=GS A0A093LL24_FULGA/343-440    AC A0A093LL24.1
#=GS F1RRT9_PIG/642-737          AC F1RRT9.2
#=GS A0A0D9RUZ8_CHLSB/672-772    AC A0A0D9RUZ8.1
#=GS S7N417_MYOBR/646-740        AC S7N417.1
#=GS A0A091V4Z6_PHORB/610-706    AC A0A091V4Z6.1
#=GS A0A091E7U8_CORBR/640-737    AC A0A091E7U8.1
#=GS F1NUH9_CHICK/646-742        AC F1NUH9.2
#=GS A0A091THM5_9AVES/646-743    AC A0A091THM5.1
#=GS A0A0G2JH35_HUMAN/624-724    AC A0A0G2JH35.1
#=GS A0A091Q8Z5_MERNU/638-734    AC A0A091Q8Z5.1
#=GS F1MCH6_BOVIN/672-772        AC F1MCH6.2
#=GS B7ZBV9_MOUSE/767-866        AC B7ZBV9.1
#=GS KCNQ3_HUMAN/770-866         AC O43525.2
#=GS A0A091S7Y1_9GRUI/346-442    AC A0A091S7Y1.1
#=GS H2QWQ8_PANTR/770-866        AC H2QWQ8.1
#=GS F6VHK7_HORSE/595-695        AC F6VHK7.1
#=GS A0A099Z4M4_TINGU/638-734    AC A0A099Z4M4.1
#=GS A0A0P7V1A1_9TELE/899-998    AC A0A0P7V1A1.1
#=GS G1RGA9_NOMLE/607-707        AC G1RGA9.1
#=GS W5M0D6_LEPOC/782-881        AC W5M0D6.1
#=GS G3QH87_GORGO/641-737        AC G3QH87.1
#=GS G1R191_NOMLE/643-739        AC G1R191.1
#=GS M3XQS8_MUSPF/642-737        AC M3XQS8.1
#=GS A0A0Q3M8F0_AMAAE/651-747    AC A0A0Q3M8F0.1
#=GS L5MIN0_MYODS/704-798        AC L5MIN0.1
#=GS A0A091PLG3_LEPDC/610-706    AC A0A091PLG3.1
#=GS H0V8Z6_CAVPO/767-867        AC H0V8Z6.1
#=GS A0A087VKI7_BALRE/628-725    AC A0A087VKI7.1
#=GS V8NNU1_OPHHA/282-375        AC V8NNU1.1
#=GS I3K398_ORENI/631-734        AC I3K398.1
#=GS A0A087VLI9_BALRE/638-734    AC A0A087VLI9.1
#=GS A0A091HPK5_BUCRH/638-734    AC A0A091HPK5.1
#=GS A0A091W3E8_OPIHO/567-664    AC A0A091W3E8.1
#=GS S7NRF4_MYOBR/1003-1103      AC S7NRF4.1
#=GS G1U889_RABIT/679-775        AC G1U889.1
#=GS H3CBD5_TETNG/762-854        AC H3CBD5.1
#=GS A0A093CZV5_TAUER/638-734    AC A0A093CZV5.1
#=GS H0VDQ0_CAVPO/649-745        AC H0VDQ0.1
#=GS A0A091MJ79_9PASS/638-734    AC A0A091MJ79.1
#=GS A0A0D9RC24_CHLSB/641-737    AC A0A0D9RC24.1
#=GS L5KJ13_PTEAL/613-708        AC L5KJ13.1
#=GS L8Y4G7_TUPCH/1021-1121      AC L8Y4G7.1
#=GS A0A093G4N3_PICPB/638-734    AC A0A093G4N3.1
#=GS I3JSA7_ORENI/771-880        AC I3JSA7.1
#=GS A0A091MGX0_9PASS/640-737    AC A0A091MGX0.1
#=GS A0A151NYJ6_ALLMI/795-896    AC A0A151NYJ6.1
#=GS A0A091G6F6_9AVES/638-735    AC A0A091G6F6.1
#=GS A0A093PTR8_9PASS/634-731    AC A0A093PTR8.1
#=GS A0A087XU80_POEFO/648-758    AC A0A087XU80.1
#=GS F6UC55_MOUSE/692-791        AC F6UC55.1
#=GS G1M2U4_AILME/641-737        AC G1M2U4.1
#=GS G7PFI1_MACFA/817-917        AC G7PFI1.1
#=GS F6QEV2_HORSE/639-735        AC F6QEV2.1
#=GS I3LG54_PIG/154-249          AC I3LG54.1
#=GS A0A091JFB6_9AVES/638-734    AC A0A091JFB6.1
#=GS A0A087QRU7_APTFO/638-734    AC A0A087QRU7.1
#=GS B8JIR6_DANRE/776-880        AC B8JIR6.1
#=GS G7PCU7_MACFA/664-760        AC G7PCU7.1
#=GS F7ASB9_MACMU/746-846        AC F7ASB9.1
#=GS A0A093FPU5_GAVST/630-727    AC A0A093FPU5.1
#=GS U3K756_FICAL/739-835        AC U3K756.1
#=GS U3I8X0_ANAPL/649-745        AC U3I8X0.1
#=GS A0A091NXN2_HALAL/643-740    AC A0A091NXN2.1
#=GS F6SB27_XENTR/653-746        AC F6SB27.1
#=GS A0A1B0GW14_HUMAN/567-667    AC A0A1B0GW14.1
#=GS A0A0A0A824_CHAVO/638-734    AC A0A0A0A824.1
#=GS A0A096NN67_PAPAN/773-873    AC A0A096NN67.1
#=GS A0A091F6N3_CORBR/638-734    AC A0A091F6N3.1
#=GS G3RYC4_GORGO/776-876        AC G3RYC4.1
#=GS F1LPA2_RAT/641-737          AC F1LPA2.3
#=GS A0A091VGC2_NIPNI/638-734    AC A0A091VGC2.1
#=GS F6TR64_HORSE/669-769        AC F6TR64.1
#=GS A0A087QRQ2_APTFO/641-738    AC A0A087QRQ2.1
#=GS A0A151NYX7_ALLMI/778-879    AC A0A151NYX7.1
#=GS B7ZBW1_MOUSE/749-848        AC B7ZBW1.1
#=GS F7CY49_CALJA/686-786        AC F7CY49.1
#=GS F1R9G5_DANRE/293-392        AC F1R9G5.1
#=GS I3N9C8_ICTTR/773-873        AC I3N9C8.1
#=GS I3MGR4_ICTTR/641-737        AC I3MGR4.1
#=GS A0A091WKW8_OPIHO/638-734    AC A0A091WKW8.1
#=GS H2TIQ8_TAKRU/767-862        AC H2TIQ8.1
#=GS H2P2L6_PONAB/674-774        AC H2P2L6.1
#=GS A0A091LX95_CARIC/652-749    AC A0A091LX95.1
#=GS A0A091JHE4_9AVES/660-757    AC A0A091JHE4.1
#=GS X1WFK8_DANRE/180-277        AC X1WFK8.1
#=GS H2TIR0_TAKRU/757-852        AC H2TIR0.1
#=GS A0A091KU28_9GRUI/508-604    AC A0A091KU28.1
#=GS A0A094N137_9AVES/485-582    AC A0A094N137.1
#=GS F7G3D5_ORNAN/678-773        AC F7G3D5.1
#=GS G3HGY7_CRIGR/664-763        AC G3HGY7.1
#=GS A0A151NYU4_ALLMI/760-861    AC A0A151NYU4.1
#=GS G5C8D4_HETGA/674-774        AC G5C8D4.1
#=GS B7ZBW2_MOUSE/736-835        AC B7ZBW2.2
#=GS H0ZQN1_TAEGU/638-734        AC H0ZQN1.1
#=GS F1PER0_CANLF/666-764        AC F1PER0.2
#=GS A0A099ZHN2_TINGU/634-731    AC A0A099ZHN2.1
#=GS L9K371_TUPCH/765-861        AC L9K371.1
#=GS G3VB89_SARHA/539-638        AC G3VB89.1
#=GS H2TIR2_TAKRU/682-765        AC H2TIR2.1
#=GS G3QZ98_GORGO/776-876        AC G3QZ98.1
#=GS H3A9P0_LATCH/772-872        AC H3A9P0.1
#=GS F7HWT6_CALJA/641-737        AC F7HWT6.1
#=GS A0A0H2UI30_RAT/809-905      AC A0A0H2UI30.1
#=GS H0X7V7_OTOGA/652-748        AC H0X7V7.1
#=GS I3KTS3_ORENI/749-839        AC I3KTS3.1
#=GS G1PXK7_MYOLU/682-782        AC G1PXK7.1
#=GS A0A094KSP0_ANTCR/638-735    AC A0A094KSP0.1
#=GS F6SB39_XENTR/749-850        AC F6SB39.1
#=GS A0A091G0N2_9AVES/638-734    AC A0A091G0N2.1
#=GS H2TIQ9_TAKRU/758-853        AC H2TIQ9.1
#=GS M4AD12_XIPMA/764-813        AC M4AD12.1
#=GS A0A093J701_STRCA/638-734    AC A0A093J701.1
#=GS A0A087X6K0_POEFO/613-678    AC A0A087X6K0.2
#=GS A0A093BWG3_TAUER/639-736    AC A0A093BWG3.1
#=GS F7DI95_MACMU/739-835        AC F7DI95.1
#=GS A0A093FVN4_TYTAL/336-433    AC A0A093FVN4.1
#=GS H2PR82_PONAB/770-866        AC H2PR82.1
#=GS A0A093QUT1_PHACA/638-734    AC A0A093QUT1.1
#=GS F7HWR5_CALJA/650-746        AC F7HWR5.1
#=GS W5M0F6_LEPOC/797-896        AC W5M0F6.1
#=GS G3VZW6_SARHA/650-746        AC G3VZW6.1
#=GS W5JY17_ASTMX/653-759        AC W5JY17.1
#=GS G3SWQ3_LOXAF/641-737        AC G3SWQ3.1
#=GS A0A091TJ07_PHALP/638-734    AC A0A091TJ07.1
#=GS A0A151NYJ8_ALLMI/796-897    AC A0A151NYJ8.1
#=GS A0A091Q8W4_LEPDC/641-738    AC A0A091Q8W4.1
#=GS F7G7S4_MONDO/617-713        AC F7G7S4.1
#=GS U3IL20_ANAPL/676-773        AC U3IL20.1
#=GS A0A091VUC1_NIPNI/641-738    AC A0A091VUC1.1
#=GS G3PTC7_GASAC/634-722        AC G3PTC7.1
#=GS A0A091SZ27_9AVES/455-551    AC A0A091SZ27.1
#=GS A0A093EPR0_9AVES/639-735    AC A0A093EPR0.1
#=GS M3ZIB7_XIPMA/664-775        AC M3ZIB7.1
#=GS F6VHH8_HORSE/651-751        AC F6VHH8.1
#=GS A0A091EP95_FUKDA/1253-1353  AC A0A091EP95.1
#=GS I3JSA8_ORENI/759-868        AC I3JSA8.1
#=GS H3CKE7_TETNG/540-640        AC H3CKE7.1
#=GS E7ET42_HUMAN/758-854        AC E7ET42.1
#=GS A0A096MBR2_POEFO/267-373    AC A0A096MBR2.1
#=GS H0ZAR3_TAEGU/677-774        AC H0ZAR3.1
#=GS A0A091L4L0_CATAU/638-734    AC A0A091L4L0.1
#=GS A0A093S200_9PASS/638-734    AC A0A093S200.1
#=GS F7CY15_CALJA/438-538        AC F7CY15.1
#=GS G1KEV7_ANOCA/698-795        AC G1KEV7.2
#=GS A0A087WZB4_HUMAN/649-745    AC A0A087WZB4.1
#=GS G1PS86_MYOLU/636-730        AC G1PS86.1
#=GS W5PN83_SHEEP/654-754        AC W5PN83.1
#=GS KCNQ3_RAT/771-867           AC O88944.2
#=GS A0A1B8XXA7_XENTR/556-657    AC A0A1B8XXA7.1
#=GS KCNQ2_HUMAN/768-868         AC O43526.2
#=GS A0A0P7XJ86_9TELE/443-539    AC A0A0P7XJ86.1
#=GS A0A093J1S3_STRCA/632-729    AC A0A093J1S3.1
#=GS M7APY8_CHEMY/630-726        AC M7APY8.1
#=GS A0A091S1Q3_NESNO/641-738    AC A0A091S1Q3.1
#=GS M3ZXU7_XIPMA/622-728        AC M3ZXU7.1
#=GS H0X1I7_OTOGA/752-852        AC H0X1I7.1
#=GS H2QKS4_PANTR/701-801        AC H2QKS4.1
#=GS G1KKP5_ANOCA/767-862        AC G1KKP5.2
#=GS A0A091P0A5_HALAL/636-732    AC A0A091P0A5.1
#=GS H3CZW3_TETNG/746-842        AC H3CZW3.1
#=GS A0A091QHS3_9GRUI/607-704    AC A0A091QHS3.1
#=GS F7D4P1_ORNAN/673-772        AC F7D4P1.1
#=GS G3IP73_CRIGR/140-235        AC G3IP73.1
#=GS G3TZD6_LOXAF/637-735        AC G3TZD6.1
#=GS E1C3B4_CHICK/750-847        AC E1C3B4.1
#=GS A0A096MSS3_PAPAN/622-719    AC A0A096MSS3.1
#=GS KCNQ2_RAT/749-848           AC O88943.1
#=GS A0A091HZH4_BUCRH/637-734    AC A0A091HZH4.1
#=GS A0A091S5J8_MERNU/615-712    AC A0A091S5J8.1
#=GS A0A0F8AND3_LARCR/794-855    AC A0A0F8AND3.1
M3VVS5_FELCA/641-737                   ...........cs--DrVSPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSLPLSSTGDG.-ISDSVWT.........
G3NLC0_GASAC/663-770                   ........rrrhr---.--RRQRDAVALESDTSLSIPSVDHEELERSFSGFSISQAKEDFFGPsffa....gsggGAGTEAA..AGPALCARVRP.FIAEGESDTDSDLYAPS.---PLSFTGEV.SCGDPAWP.........
G3SBP3_GORGO/723-823                   ...........qe--DtPGCRPPEGTLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
G1T2H7_RABIT/641-737                   ........ysdhi---.-SPHHGRSITRDSDTPLSLMSLNHEELERSPSGFSISQDRDEYAFG............-----PS..-AGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
KCNQ3_MOUSE/771-867                    .........ysdh---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..SGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPMSSTGDG.-ISDSIWT.........
S9WNY3_CAMFR/794-889                   ..........per---.VSPGQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..IGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
M3WAG9_FELCA/647-745                   .......astefl---.----RHEAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLDGL............---HSCY..AAAAPCATVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
M3Y9Y5_MUSPF/668-766                   .......astefl---.----RHEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCG..AAAAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A0P7VT09_9TELE/560-643               .......dgpspg---.----QGRTLGRDTDTPLSLLSVNHEELERSPSGFSISQEREDLT--............-------..--------XKR.YLAEGETDTDTDPFTPS.GPLPLSSTGEG.-FPESVWN.........
A0A091U5Q6_PHALP/349-446               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
M7BD60_CHEMY/655-755                   ............n-ED.ITAKHHDSALRDSDTSISIPSVDHEELERSFSGFSISQSKDNLD--............ILNNGCY..AAVAPCAKIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
W5P9E5_SHEEP/645-741                   ...........cs--DrVSPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYAFG............P------..SGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
F1PVZ4_CANLF/673-769                   ...........cs--DrVSPRHRRSLTRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..SGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
A0A0G2JFQ2_MOUSE/739-838               .........egtp---.-ACRPSEAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ALG-SCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVAWA.........
A0A091HPU0_CALAN/638-735               ...........ss--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQERDDFPF-............----GPN..GGSSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A091I973_CALAN/639-735               ............n-ED.ITTKPHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGW-.........
A0A091T971_NESNO/636-732               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A091N2R5_APAVI/644-741               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A091DFP0_FUKDA/665-760               ..........ser---.ISPRQRCSLTRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYTFG............P------..GGGSSWMREKR.YLAEGETDTDTDPFTPS.GSLPLSSTGDG.-ISDSIWT.........
A0A093EJA9_TYTAL/567-663               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
K7FEF1_PELSI/638-734                   .........ssdr---.ISPRQKRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDKDDFPFG............P------..NGGSSWLREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
V8NB24_OPHHA/348-441                   .......hsdrfs---.-----SRQRQRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFLFG............P------..NGGTSWMKEKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISESIWT.........
F7D4R0_ORNAN/681-780                   ............n-ED.VTTKHHESALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............-VLNSCY..AAVAPCAKIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
G3TXG4_LOXAF/629-727                   .........rhed---.-VARPPEGCLRDSDTSISIPSVDHEELERSFSGFSISQSKEQLD--............A--LGGY..TAVAPCVKVRP.YIAEGESDTDSDLCTPC.GPPPRSATSEG.PFGDLGWA.........
A0A093LPN2_FULGA/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
F1M6X3_RAT/749-848                     .........egtp---.-ACRPSEAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............-ALASCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVAWA.........
K7FZ48_PELSI/673-773                   ............n-ED.ITAKHHDSALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............VLNNGCY..AAVAPCAKIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
W5LDV5_ASTMX/272-370                   .........edgk---.AGGLSQQQAGAESDTSISIPSVDHEELERSFSGFSISQSKENLD--............FLNNAYF..SGVARSSKVRP.YIAEGESDTDSDLCAPS.---PHSATGEG.AYGDRGWT.........
G1NJK4_MELGA/645-741                   ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
G1L416_AILME/668-767                   ......rastefl---.----RHEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ALNSG-Y..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVG--rg.......
A0A096M9K0_POEFO/264-370               ........eragt---.--ERNGDEAKLDSDTSVSIPSVDHEELERSFSGFSISQSRENLDFLnngfypsagpgeQPAGGSG..GGSVRRAARRP.YIAQGESDSDSELCAPS.PHSDRAWTG--.--------tk.......
F7ASD7_MACMU/746-846                   ...........qe--DaPGCRPPEGTLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
F6WQP9_MONDO/771-870                   ............n-ED.MASKHHESALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............-VLNSCY..AAVAPCAKIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
G1N3R9_MELGA/679-776                   ............n-ED.ITTKHHESALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
G3NFU0_GASAC/779-863                   ......gggggge---.-------EVKPDSDASVSIQSMDHEDLEHSFGGFSTSKSKDNLNFLnn.......gfySSANHKG..GGGASSATLRP.YIAEGESDSDSELCAP-.-----------.--------.........
B7ZBV3_MOUSE/623-722                   .........egtp---.-ACRPSEAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ALG-SCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVAWA.........
H2LQ97_ORYLA/616-720                   ............l-QDlSAGPGRTTGRQGGDSPLSMLSVNHEELERSPSGFSISVDREGDERV............PTEADMA..TGEVSWTRPRPsYLAEGETDTDTDPFTPSgGALPLSSTGEG.-FCDAEWN.........
G5C6Q1_HETGA/779-874                   ..........seh---.VSPRQRRSLTRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYAFG............P------..GGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A094LEL7_9AVES/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A0Q3Q3K7_AMAAE/767-864               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
L5JYN1_PTEAL/694-793                   ...........he--DaPACRPHEAVPRDSDTSISIPSVDHEELERSSSGFSISQSRENLD--............--ALGCH..AAAAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
W5N4S1_LEPOC/747-843                   .........mdyl---.-SPRQGRTVVRDTDTPLSLLSVNHEELERSPSGFSISQDRDDLTF-............----GPC..GGGSSWMKEKR.YLAEGETDTDTDPFTPS.GPLPLSSTGEG.-FPDSVWT.........
A0A0F8AND3_LARCR/900-943               ........ggggg---.----------------------------------------------............-------..GGAARCATVRP.YIAEGESDSDSELCVPS.PHSDQAWTG--.--------tk.......
A0A091LCN0_CATAU/643-740               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
H2L5I0_ORYLA/771-880                   .........rqrc---.-QQDAASAAAVESDTSLSIPSVDHEELERSFSGFSISQAKEDFFGPpyftg..sggggAAGTEAG..TGHSLCARVRP.FIAEGESDTDSDLYAPS.---PLSFTGEV.PCGEKGWP.........
KCNQ3_BOVIN/764-860                    ...........cs--DrVSPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYAFG............P------..SGGSSWMREKR.YLAEGETDTDTEPFTPS.GSLPLSSTGDG.-ISDSIWT.........
F7ASA7_MACMU/755-855                   ...........qe--DaPGCRPPEGTLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A093LL24_FULGA/343-440               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
F1RRT9_PIG/642-737                     ...........se--R.VSPRQRPSLTRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYAFG............P------..GGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A0D9RUZ8_CHLSB/672-772               ...........qe--DaPGCRPPEGTLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
S7N417_MYOBR/646-740                   .........tdph---.-GLRQRRSFTRDSDTPLSLMSVDHEELERSPSGFSISQDRDDVFG-............------L..GGGSSWMREKR.YLAEGETDTDTDPFTPS.SSMPLSSTGDG.-ISDSIWT.........
A0A091V4Z6_PHORB/610-706               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A091E7U8_CORBR/640-737               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
F1NUH9_CHICK/646-742                   ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGCAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A091THM5_9AVES/646-743               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A0G2JH35_HUMAN/624-724               ...........qe--DtPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A091Q8Z5_MERNU/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQERDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
F1MCH6_BOVIN/672-772                   ...........pe--DaPACRPHEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDMGWA.........
B7ZBV9_MOUSE/767-866                   .........egtp---.-ACRPSEAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ALG-SCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVAWA.........
KCNQ3_HUMAN/770-866                    .........ysdr---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
A0A091S7Y1_9GRUI/346-442               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQERDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
H2QWQ8_PANTR/770-866                   .........ysdr---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
F6VHK7_HORSE/595-695                   ...........he--DaPACRSHEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A099Z4M4_TINGU/638-734               ...........ys--DkVSPRQRRSFTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A0P7V1A1_9TELE/899-998               .........pedg---.--RQQQDSALRESDTSLSIPSVDHEELERSFSGFSISQSRENLD--............FLSGGYF..GGVALCAKVRP.YIAEGESDTDSDLCTPC.GHSPHSTAGEG.PLTDRGWS.........
G1RGA9_NOMLE/607-707                   ...........qe--DaPGCRPPEGTLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
W5M0D6_LEPOC/782-881                   ..........rae---.-DGKQHDSALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............FLNNAYF..GGVALCAKVRP.YIAEGESDTDSDLCTPC.GPSPHSATGEG.AYGDRGWS.........
G3QH87_GORGO/641-737                   .........ysdr---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
G1R191_NOMLE/643-739                   .........ysdr---.ISPRQRRSVTRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
M3XQS8_MUSPF/642-737                   ..........ldr---.VSPRQRQSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYMFG............P------..SGGSSWMREKR.YLAEGETDTDTDPFTPS.GSIPLSSTGDG.-ISDSMWT.........
A0A0Q3M8F0_AMAAE/651-747               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDKDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
L5MIN0_MYODS/704-798                   .........tdph---.-GLRQRRSFTRDSDTPLSLMSVDHEELERSPSGFSISQDRDDVFG-............------S..GGGSSWMREKR.YLAEGETDTDTDPFTPS.SSMPLSSTGDG.-ISDSIWT.........
A0A091PLG3_LEPDC/610-706               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
H0V8Z6_CAVPO/767-867                   ...........le--DaPACRPHEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............-ALSSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A087VKI7_BALRE/628-725               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
V8NNU1_OPHHA/282-375                   ............n-ED.VTAKHPDSALRDSDTSISIPSVDHEELERSFSGFSISQSRENLD--............ILNNGCY..TAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATA--.--------iaaqtf...
I3K398_ORENI/631-734                   ............l-QDlSVGLGRTTGGQGGDSPLSMLSVNHEELERSPSGFSISGEREGEN-I............SMGAGLA..PGDPGWTRPRPsYLAEGETDTDTDPFTPSgGPLPLSSTGEG.-FGDAVWT.........
A0A087VLI9_BALRE/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A091HPK5_BUCRH/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A091W3E8_OPIHO/567-664               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
S7NRF4_MYOBR/1003-1103                 ...........he--DtPASRPHEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLDG-............-L-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFADVGWA.........
G1U889_RABIT/679-775                   ........ysdhi---.-SPHHGRSITRDSDTPLSLMSLNHEELERSPSGFSISQDRDEYAFG............-----PS..-AGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
H3CBD5_TETNG/762-854                   ...........rk--E.SSGTPGEDAKPDSDVSVSIPSVDHEELERSFSGFSISQSRENLDFLksnfc..lsstnLGDHHRG..GAATPCAAIRP.YIAEGESDSDSELCPP-.-----------.--------.........
A0A093CZV5_TAUER/638-734               ...........ys--DkMSSRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..SGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
H0VDQ0_CAVPO/649-745                   .........ysdh---.ISPRQRRSLTRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYAFG............P------..SGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A091MJ79_9PASS/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQERDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A0D9RC24_CHLSB/641-737               .........ysdr---.ISPQQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
L5KJ13_PTEAL/613-708                   ...........gs--DwVSPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDVFG-............------P..GGGPSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
L8Y4G7_TUPCH/1021-1121                 ...........le--DaPGGRPHEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAAAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A093G4N3_PICPB/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQERDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
I3JSA7_ORENI/771-880                   ......rnrrhrc---.----HREVTAVDSDTSLSIPSVDHEELERSFSGFSISQAKEDFFGPsfftg..lgggaGAGTEAG..GGPSLCARVRP.LLAEGESDTDSDLCAPS.---PLSFTGEV.SGGERGWA.........
A0A091MGX0_9PASS/640-737               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A151NYJ6_ALLMI/795-896               ...........rn-DD.VTTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..ASVAPCAKIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A091G6F6_9AVES/638-735               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A093PTR8_9PASS/634-731               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A087XU80_POEFO/648-758               .......rhrrhr---.---CQHDATAVESDTSLSIPSVDHEELERSFSGFSISQAKEDFFGPsffag.sgggggGAAAEAV..GGRSICARVRP.FIAEGESDTDSDLYAPS.---PLSFTGDA.SCGERGWP.........
F6UC55_MOUSE/692-791                   .........egtp---.-ACRPSEAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ALG-SCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVAWA.........
G1M2U4_AILME/641-737                   ...........cs--DrVSPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYMFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
G7PFI1_MACFA/817-917                   ...........qe--DaPGCRPPEGTLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
F6QEV2_HORSE/639-735                   ...........ys--DrVSPRQRRSITRDSDTPLSLMSVNHEELEQSPSGFSISQDRDDYVFG............P------..SGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
I3LG54_PIG/154-249                     ...........se--R.VSPRQRPSLTRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYAFG............P------..GGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A091JFB6_9AVES/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A087QRU7_APTFO/638-734               ...........ys--DkASPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
B8JIR6_DANRE/776-880                   ......srrsrrp---.----VQQQAAVESDTSLSIPSVDHEELDRSFSGFSISQAREEDYVP............PVSLGPFggGGGTLCTRIRP.YLAEGESDTDSDLYTPG.APSPLSFTGEG.TFGDRMWP.........
G7PCU7_MACFA/664-760                   .........ysdr---.ISPQQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
F7ASB9_MACMU/746-846                   ...........qe--DaPGCRPPEGTLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A093FPU5_GAVST/630-727               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNSCY..AAV---AKIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
U3K756_FICAL/739-835                   ..........ged---.-MAKHHESALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
U3I8X0_ANAPL/649-745                   ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A091NXN2_HALAL/643-740               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
F6SB27_XENTR/653-746                   ........lkeas---.---PTQRRSFRDSDTPLSLLSVNHDELQRSPSGFSISQEKEDFSF-............------G..NNGSNWMREKR.FLAEGETDTDTDPFTPS.GPITLSSTGDG.-ISESAWT.........
A0A1B0GW14_HUMAN/567-667               ...........qe--DtPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A0A0A824_CHAVO/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A096NN67_PAPAN/773-873               ...........qe--DaPGCRPPEGTLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A091F6N3_CORBR/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQERDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
G3RYC4_GORGO/776-876                   ...........qe--DtPGCRPPEGTLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
F1LPA2_RAT/641-737                     .........ysdh---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..SGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPMSSTGDG.-ISDSIWT.........
A0A091VGC2_NIPNI/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
F6TR64_HORSE/669-769                   ...........he--DaPACRSHEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A087QRQ2_APTFO/641-738               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A151NYX7_ALLMI/778-879               ...........rn-DD.VTTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..ASVAPCAKIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
B7ZBW1_MOUSE/749-848                   .........egtp---.-ACRPSEAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ALG-SCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVAWA.........
F7CY49_CALJA/686-786                   ...........qe--DaPGCRPPEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
F1R9G5_DANRE/293-392                   .......shspss---.---NVSQTGGHRVGTPLSLLSVTHEELERSPSGFSISAEKEEVTGK............A---SGL..TAGSSWGRDRR.YLAEGETDTDTDPFTPS.GPVPPSSTGDG.FQSDGAW-g........
I3N9C8_ICTTR/773-873                   ...........le--DaAVCRPHEAALRDSDTSISIPSVDHEELERSFSGFSISQSRENLD--............AL-SGGY..AAAAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGEVGWA.........
I3MGR4_ICTTR/641-737                   .........ysdh---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYMFG............-----P-..SAGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A091WKW8_OPIHO/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSGWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
H2TIQ8_TAKRU/767-862                   ........rrrrq---.--TCQQDGTAAESDTSLSIPSVDHEELERSFSGFSISQAKEDFF--............--GPSFF..AGTAGCPRVRP.FIAEGESDTDSDLYAPS.---PVSFTGDT.SCGERPWP.........
H2P2L6_PONAB/674-774                   .........qedt---.LGCRPPEGTLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A091LX95_CARIC/652-749               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A091JHE4_9AVES/660-757               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
X1WFK8_DANRE/180-277                   .........aedg---.-RPASQAQAGAESDTSISIPSVDHEELERSFSGFSISQSKENLD--............FLNNAYF..SGVSRCTKVRP.YIAEGESDTDSDLCAPS.---PHSATGDG.AYADRGWT.........
H2TIR0_TAKRU/757-852                   ........rrrrq---.--TCQQDGTAAESDTSLSIPSVDHEELERSFSGFSISQAKEDFF--............--GPSFF..AGTAGCPRVRP.FIAEGESDTDSDLYAPS.---PVSFTGDT.SCGERPWP.........
A0A091KU28_9GRUI/508-604               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A094N137_9AVES/485-582               ............n-ED.ITTKHHESALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
F7G3D5_ORNAN/678-773                   ........sprqr---.--RRQRPSLTRDSDTPLSLLSVNHEELARSPSGFSISQERDDYLFG............P------..SGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-VSDSVWT.........
G3HGY7_CRIGR/664-763                   .........egap---.-ACRPPEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ALG-SCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A151NYU4_ALLMI/760-861               ...........rn-DD.VTTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..ASVAPCAKIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
G5C8D4_HETGA/674-774                   ...........le--DtPACRPHEGIPRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............-ALSGCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDMGWA.........
B7ZBW2_MOUSE/736-835                   .........egtp---.-ACRPSEAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ALG-SCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVAWA.........
H0ZQN1_TAEGU/638-734                   ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQERDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
F1PER0_CANLF/666-764                   ......asteflr---.-----PEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A099ZHN2_TINGU/634-731               ............n-ED.IATKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
L9K371_TUPCH/765-861                   .........ysdr---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDKDDYMFD............P------..GGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
G3VB89_SARHA/539-638                   ............n-ED.MAVKHHESALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............-MLNSCY..AAVAPCAKIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
H2TIR2_TAKRU/682-765                   ........rrrrq---.--TCQQDGTAAESDTSLSIPSVDHEELERSFSGFSISQAKEDFFG-............---PSFF..AGTA---GVRP.FIAEGESDTDSDLYAPS.---PVSFTGD-.--------.........
G3QZ98_GORGO/776-876                   ...........qe--DtPGCRPPEGTLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
H3A9P0_LATCH/772-872                   ..........aee---.APVRPHDILLRDSDTSISIPSVDHEELERSFSGFSISQSKENMD--............ILNTGIF..SGAAPCAKRRP.YIAEGESDSDSDLCTPS.GPPPRSSTGEG.PCGDMGWS.........
F7HWT6_CALJA/641-737                   .........ysdr---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A0H2UI30_RAT/809-905                 .........ysdh---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..SGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPMSSTGDG.-ISDSIWT.........
H0X7V7_OTOGA/652-748                   .........ysdg---.ISPRQRCSVTRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYAFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
I3KTS3_ORENI/749-839                   .....sngmgggg---.------EEGKPDSDTSISIPSVDHEELERSFSGFSISQSRDNLDFLnngf...yssnnLGDHHGG..GGAACCTAVRS.YIAEGESDSDSELCVP-.-----------.--------.........
G1PXK7_MYOLU/682-782                   ...........he--DtPASRPHEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLDG-............-L-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFADMGWA.........
A0A094KSP0_ANTCR/638-735               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
F6SB39_XENTR/749-850                   ........veegs---.-GKHRDPAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLE--............ILNNGAV..AGPGPCHKVRP.YIAEGESDTDSDLCTPC.GPPARSTTGEG.PYGDMGWP.........
A0A091G0N2_9AVES/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQERDDFPFG............------L..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
H2TIQ9_TAKRU/758-853                   ........rrrrq---.--TCQQDGTAAESDTSLSIPSVDHEELERSFSGFSISQAKEDFF--............--GPSFF..AGTAGCPRVRP.FIAEGESDTDSDLYAPS.---PVSFTGDT.SCGERPWP.........
M4AD12_XIPMA/764-813                   .......dragpe---.---RNGDEAKPDSDTSVSIPSVDHEELERSFSGFSISQSRENLDF-............-------..-----------.-----------------.-----------.--------ln.......
A0A093J701_STRCA/638-734               ...........ys--DkVSPRQRRSFTRDSDTPLSLLSVNHEELERSPSGFSISQDKDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A087X6K0_POEFO/613-678               terptvlpisslq---.----------------------------------------------............--DLSAA..AGEASWTRTRPsYLAEGETDTDTDPFTPSgGALPLSSTGEG.-FGDAEWN.........
A0A093BWG3_TAUER/639-736               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
F7DI95_MACMU/739-835                   .........ysdr---.ISPQQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
A0A093FVN4_TYTAL/336-433               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
H2PR82_PONAB/770-866                   .........ysdr---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
A0A093QUT1_PHACA/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
F7HWR5_CALJA/650-746                   .........ysdr---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
W5M0F6_LEPOC/797-896                   ..........rae---.-DGKQHDSALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............FLNNAYF..GGVALCAKVRP.YIAEGESDTDSDLCTPC.GPSPHSATGEG.AYGDRGWS.........
G3VZW6_SARHA/650-746                   .........yqer---.ISPRQRRSFTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDYLFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
W5JY17_ASTMX/653-759                   ..........rqr---.RSRRSRHQAGVESDTSLSIPSVDHEELERSFSGFSISQAKEEDYFPp.........tiLAPFRAG..ERESISSNARP.RLAEGESDTDSDLYTPG.GPSPLSFTGETlPFGDRGWP.........
G3SWQ3_LOXAF/641-737                   .........vsdh---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYMFG............P------..SGGSGWMWEKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A091TJ07_PHALP/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQERDDFPFG............P------..SGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A151NYJ8_ALLMI/796-897               ...........rn-DD.VTTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..ASVAPCAKIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A091Q8W4_LEPDC/641-738               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
F7G7S4_MONDO/617-713                   ............y-QDrISPRQRRSFTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDYLFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
U3IL20_ANAPL/676-773                   ............n-ED.ITTKHHESALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A091VUC1_NIPNI/641-738               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
G3PTC7_GASAC/634-722                   ............l-QDlSAGPGRTTGARGGDSPLSMLSV-HDELERS-SGFSISGSRMKPA--............-------..-G----RDPDPsYLAEGETDTDTDPFTPSgGALPLSSPGEG.-FGDAVWN.........
A0A091SZ27_9AVES/455-551               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A093EPR0_9AVES/639-735               ...........ys--DkVSPRQRRSFTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
M3ZIB7_XIPMA/664-775                   ......rhrrhrc---.----QHDPTVVESDTSLSIPSVDHEELERSFSGFSISQAKEDFFGPsffagsggggggGAAAEAV..GGRSICARVRP.FIAEGESDTDSDLYAPS.---PLSFTGET.SCGERGW-l........
F6VHH8_HORSE/651-751                   ...........he--DaPACRSHEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A091EP95_FUKDA/1253-1353             ...........le--DaPACRPHEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............-ALSSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
I3JSA8_ORENI/759-868                   ......rnrrhrc---.----HREVTAVDSDTSLSIPSVDHEELERSFSGFSISQAKEDFFGPsfftg..lgggaGAGTEAG..GGPSLCARVRP.LLAEGESDTDSDLCAPS.---PLSFTGEV.SGGERGWA.........
H3CKE7_TETNG/540-640                   ............l-QDqAGGVARTTGGRGADTPLSMLSVNHEELERSPSGFSISGERDGED--............--GGGPS..AGATVRTRARPtHLAEGETDTDTDPFTPSgGPLPLSSTGEG.-FGESVWA.........
E7ET42_HUMAN/758-854                   .........ysdr---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
A0A096MBR2_POEFO/267-373               ........eragt---.--ERNGDEAKLDSDTSVSIPSVDHEELERSFSGFSISQSRENLDFLnngfypsagpgeQPAGGSG..GGSVRRAARRP.YIAQGESDSDSELCAPS.PHSDRAWTG--.--------tk.......
H0ZAR3_TAEGU/677-774                   ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A091L4L0_CATAU/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
A0A093S200_9PASS/638-734               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQERDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
F7CY15_CALJA/438-538                   ...........qe--DaPGCRPPEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
G1KEV7_ANOCA/698-795                   ............n-ED.VTAKHPESALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............VLNNGCY..TAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A087WZB4_HUMAN/649-745               .........ysdr---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
G1PS86_MYOLU/636-730                   .........tdph---.-GLRQRRSFTRDSDTPLSLMSVDHEELERSPSGFSISQDRDDVFG-............------L..GGGSSWMREKR.YLAEGETDTDTDPFTPS.SSMPLSSTGDG.-ISDSIWT.........
W5PN83_SHEEP/654-754                   ...........pe--DaPACRPHEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDMGWA.........
KCNQ3_RAT/771-867                      .........ysdh---.ISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..SGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPMSSTGDG.-ISDSIWT.........
A0A1B8XXA7_XENTR/556-657               ........veegs---.-GKHRDPAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLE--............ILNNGAV..AGPGPCHKVRP.YIAEGESDTDSDLCTPC.GPPARSTTGEG.PYGDMGWP.........
KCNQ2_HUMAN/768-868                    ...........qe--DtPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
A0A0P7XJ86_9TELE/443-539               ....slhtrteng---.-------KQQPESDTSISIPSVDHEELERSFSGFSISQSKENLD--............FLNNAYF..GGVARCAKVRP.YIAEGESDTDSDLCTPC.APSPHSAPGDR.--------gwsgt....
A0A093J1S3_STRCA/632-729               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
M7APY8_CHEMY/630-726                   .........nsdr---.ISPRQKRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDKDDFPFG............P------..NGGSTWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSLWT.........
A0A091S1Q3_NESNO/641-738               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
M3ZXU7_XIPMA/622-728                   ............l-QDlSAGRGRTTGGRGGDSPLSLLSVNHEELERSPSGFSISGEREGEAGLt..........cRVGAAVA..AGEASWTRTRPsYLAEGETDTDTDPFTPSgGALPLSSTGEG.-FGDAEWN.........
H0X1I7_OTOGA/752-852                   ............q-EDaPACRAHEGALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............-ALSSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDMGWP.........
H2QKS4_PANTR/701-801                   ...........qe--DtPGCRPPEGTLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............AL-NSCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVGWA.........
G1KKP5_ANOCA/767-862                   .........seri---.-PSRQKHSVTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFLFG............P------..NGGSSWMKEKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-LSDSIWT.........
A0A091P0A5_HALAL/636-732               ...........ys--DkVSPRQRRSLTRDSDTPLSLLSVNHEELERSPSGFSISQDRDDFPFG............P------..NGGSAWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSIWT.........
H3CZW3_TETNG/746-842                   .......sqsrrr---.--RRRQTCQQAESDTSLSIPSVDHEELERSFSGFSISQAKEDFF--............--GASFF..AGPPVCPRDRP.FIAEGESDTDSDLYAPS.---PVSFTGDI.FCGEKPWP.........
A0A091QHS3_9GRUI/607-704               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
F7D4P1_ORNAN/673-772                   ............n-ED.VTTKHHESALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............-VLNSCY..AAVAPCAKIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
G3IP73_CRIGR/140-235                   .........pdhi---.-SPHQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYMFG............P------..SGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPMSSTGDG.-ISDSIWT.........
G3TZD6_LOXAF/637-735                   .........rhed---.-VARPPEGCLRDSDTSISIPSVDHEELERSFSGFSISQSKEQLD--............A--LGGY..TAVAPCVKVRP.YIAEGESDTDSDLCTPC.GPPPRSATSEG.PFGDLGWA.........
E1C3B4_CHICK/750-847                   ............n-ED.ITTKHHESALRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A096MSS3_PAPAN/622-719               ........tddsv---.SCPQQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFG............P------..NGGSSWMREKR.YLAEGETDTDTDPFTPS.GSMPLSSTGDG.-ISDSVWT.........
KCNQ2_RAT/749-848                      .........egtp---.-ACRPSEAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLN--............-ALASCY..AAVAPCAKVRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFGDVAWA.........
A0A091HZH4_BUCRH/637-734               ............n-ED.ITTKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A091S5J8_MERNU/615-712               ............n-ED.IATKHHESAMRDSDTSISIPSVDHEELERSFSGFSISQSKENLD--............ILNNGCY..AAVA---KIRP.YIAEGESDTDSDLCTPC.GPPPRSATGEG.PFSDMGWS.........
A0A0F8AND3_LARCR/794-855               ....sgtggggge---.-------EIKPDSDTSISIPSVDHEELERSFSGFSISQSRENLDF-............-LNNSFY..-----------.-----------------.-----------.--------sssnnlgdh
#=GC seq_cons                          ............p.....us+p+cShhRDSDTslSl.SVsHEELERS.SGFSISQs+-shs....................h..uusushh+.+..YlAEGEoDTDoD.hTPs.Gs.PhSuTG-G..hSDssWo.........
//
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