GenomeNet

Database: Pfam
Entry: PLC-beta_C
LinkDB: PLC-beta_C
Original site: PLC-beta_C 
#=GF ID   PLC-beta_C
#=GF AC   PF08703.7
#=GF DE   PLC-beta C terminal
#=GF AU   Mistry J
#=GF SE   pdb_1jad
#=GF GA   24.40 24.40;
#=GF TC   24.40 24.40;
#=GF NC   23.90 24.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF DR   INTERPRO; IPR014815;
#=GF DR   SCOP; 1jad; fa;
#=GF CC   This domain corresponds to the alpha helical C terminal domain
#=GF CC   of phospholipase C beta.
#=GF SQ   235
#=GS G3WSF5_SARHA/859-1006       AC G3WSF5.1
#=GS H0WVR1_OTOGA/1029-1202      AC H0WVR1.1
#=GS F1PL90_CANFA/921-1094       AC F1PL90.2
#=GS G3GSB8_CRIGR/806-948        AC G3GSB8.1
#=GS M4A280_XIPMA/1035-1208      AC M4A280.1
#=GS A0A067RK16_ZOONE/820-961    AC A0A067RK16.1
#=GS H2T5M1_TAKRU/1030-1169      AC H2T5M1.1
#=GS G7PAX0_MACFA/864-1011       AC G7PAX0.1
#=GS A0A096MPE1_PAPAN/1028-1201  AC A0A096MPE1.1
#=GS W5L6G5_ASTMX/1045-1217      AC W5L6G5.1
#=GS R9PXY3_RAT/902-1054         AC R9PXY3.2
#=GS H2ND03_PONAB/999-1172       AC H2ND03.1
#=GS H9J6P8_BOMMO/813-947        AC H9J6P8.1
#=GS M3WLN6_FELCA/926-1074       AC M3WLN6.1
#=GS E0W3C1_PEDHC/1026-1190      AC E0W3C1.1
#=GS G1KBF0_ANOCA/1006-1147      AC G1KBF0.2
#=GS I3K794_ORENI/1012-1185      AC I3K794.1
#=GS G3NT25_GASAC/951-1027       AC G3NT25.1
#=GS G3S3I2_GORGO/1035-1208      AC G3S3I2.1
#=GS A0A087XPB2_POEFO/975-1162   AC A0A087XPB2.2
#=GS L5LFG6_MYODS/997-1170       AC L5LFG6.1
#=GS M3ZYR6_XIPMA/937-1108       AC M3ZYR6.1
#=GS I3MBL6_SPETR/1030-1203      AC I3MBL6.1
#=GS T1K583_TETUR/457-631        AC T1K583.1
#=GS M7B1J2_CHEMY/923-1064       AC M7B1J2.1
#=GS G3WJX4_SARHA/979-1152       AC G3WJX4.1
#=GS A0A0D9SF51_HUMAN/902-960    AC A0A0D9SF51.1
#=GS I3N4U4_SPETR/977-1152       AC I3N4U4.1
#=GS G1MI45_AILME/998-1171       AC G1MI45.1
#=GS B3MUI8_DROAN/1108-1255      AC B3MUI8.1
#=GS G3ICJ1_CRIGR/979-1154       AC G3ICJ1.1
#=GS G5B6Q5_HETGA/999-1172       AC G5B6Q5.1
#=GS E2AT88_CAMFO/1088-1245      AC E2AT88.1
#=GS F7D8C0_MACMU/981-1156       AC F7D8C0.1
#=GS U3IZQ7_ANAPL/917-1026       AC U3IZQ7.1
#=GS H3CZG1_TETNG/748-922        AC H3CZG1.1
#=GS A0A087XE40_POEFO/1036-1209  AC A0A087XE40.1
#=GS I3IYR6_ORENI/1008-1172      AC I3IYR6.1
#=GS G3WSF6_SARHA/882-1041       AC G3WSF6.1
#=GS M3YAI4_MUSPF/980-1155       AC M3YAI4.1
#=GS G3T334_LOXAF/997-1170       AC G3T334.1
#=GS W5QG22_SHEEP/959-1134       AC W5QG22.1
#=GS H2T0J2_TAKRU/1016-1188      AC H2T0J2.1
#=GS G3QEQ0_GORGO/981-1156       AC G3QEQ0.1
#=GS L9KV79_TUPCH/1005-1173      AC L9KV79.1
#=GS A0A087WW73_HUMAN/923-1072   AC A0A087WW73.1
#=GS M4A2J9_XIPMA/935-1108       AC M4A2J9.1
#=GS A0A0D9SG17_HUMAN/902-961    AC A0A0D9SG17.1
#=GS H2Q961_PANTR/978-1153       AC H2Q961.1
#=GS W5PHF5_SHEEP/948-1096       AC W5PHF5.1
#=GS A0A0G2JZ43_RAT/976-1151     AC A0A0G2JZ43.1
#=GS M3WXT8_FELCA/1-145          AC M3WXT8.1
#=GS F4X6N0_ACREC/1086-1243      AC F4X6N0.1
#=GS PLCB1_BOVIN/1003-1176       AC P10894.1
#=GS Q7ZZ38_DANRE/1014-1184      AC Q7ZZ38.2
#=GS W5P6K6_SHEEP/1008-1181      AC W5P6K6.1
#=GS F6Y4X0_MONDO/982-1155       AC F6Y4X0.2
#=GS A0A0D9SGI7_HUMAN/90-230     AC A0A0D9SGI7.1
#=GS U3JED2_FICAL/981-1156       AC U3JED2.1
#=GS F6ZKK2_MACMU/902-1051       AC F6ZKK2.1
#=GS I3IX39_ORENI/1030-1090      AC I3IX39.1
#=GS I3K2K2_ORENI/966-1135       AC I3K2K2.1
#=GS H0Z7L9_TAEGU/946-1091       AC H0Z7L9.1
#=GS E1BR11_CHICK/955-1130       AC E1BR11.2
#=GS H2T5L9_TAKRU/1004-1177      AC H2T5L9.1
#=GS A0A091DLC4_FUKDA/950-1124   AC A0A091DLC4.1
#=GS H3CZG0_TETNG/898-1010       AC H3CZG0.1
#=GS E4XX08_OIKDI/20-125         AC E4XX08.1
#=GS F6R8R8_MACMU/902-1075       AC F6R8R8.1
#=GS F6TQH3_HORSE/967-1142       AC F6TQH3.1
#=GS M7BC37_CHEMY/689-862        AC M7BC37.1
#=GS K7IWF5_NASVI/1075-1234      AC K7IWF5.1
#=GS W4Y6U5_STRPU/420-583        AC W4Y6U5.1
#=GS F1RQ08_PIG/1022-1195        AC F1RQ08.2
#=GS H2T0J1_TAKRU/999-1171       AC H2T0J1.1
#=GS H2LLI2_ORYLA/969-1127       AC H2LLI2.1
#=GS G1QR36_NOMLE/822-997        AC G1QR36.2
#=GS E9PYI3_MOUSE/951-1126       AC E9PYI3.1
#=GS G7PGY4_MACFA/922-1095       AC G7PGY4.1
#=GS W5LF50_ASTMX/899-1071       AC W5LF50.1
#=GS E9IZ80_SOLIN/1027-1184      AC E9IZ80.1
#=GS A0A091E039_FUKDA/1027-1200  AC A0A091E039.1
#=GS M3ZWG8_XIPMA/1088-1250      AC M3ZWG8.1
#=GS G3SQN0_LOXAF/876-1049       AC G3SQN0.1
#=GS A0A087Y6H2_POEFO/973-1144   AC A0A087Y6H2.2
#=GS F1NLL3_CHICK/903-1056       AC F1NLL3.2
#=GS F7I4D1_CALJA/978-1153       AC F7I4D1.1
#=GS H2ZXW7_LATCH/891-1005       AC H2ZXW7.1
#=GS E2RT75_CANFA/981-1156       AC E2RT75.1
#=GS G3PFZ8_GASAC/1002-1175      AC G3PFZ8.1
#=GS PLCB3_HUMAN/1029-1202       AC Q01970.2
#=GS PLCB3_HUMAN/1029-1202       DR PDB; 4GNK E; 1029-1192;
#=GS PLCB3_RAT/1029-1202         AC Q99JE6.2
#=GS H2T5M0_TAKRU/1034-1173      AC H2T5M0.1
#=GS H0VMR3_CAVPO/953-1126       AC H0VMR3.1
#=GS G1SR80_RABIT/962-1137       AC G1SR80.2
#=GS V8N9T1_OPHHA/4-117          AC V8N9T1.1
#=GS F6X322_MOUSE/13-161         AC F6X322.1
#=GS V8P608_OPHHA/912-1086       AC V8P608.1
#=GS E7FGQ4_DANRE/306-417        AC E7FGQ4.1
#=GS G3Q8A3_GASAC/964-1130       AC G3Q8A3.1
#=GS E1B7M6_BOVIN/964-1139       AC E1B7M6.2
#=GS H3BYJ8_TETNG/961-1114       AC H3BYJ8.1
#=GS H0YCJ2_HUMAN/744-893        AC H0YCJ2.1
#=GS PLCB1_RAT/1003-1176         AC P10687.1
#=GS H0V8S9_CAVPO/923-1096       AC H0V8S9.1
#=GS A0A087ZZ32_APIME/1092-1248  AC A0A087ZZ32.1
#=GS I3IX38_ORENI/1030-1203      AC I3IX38.1
#=GS L5K2I7_PTEAL/1113-1288      AC L5K2I7.1
#=GS PLCB3_MOUSE/1029-1202       AC P51432.2
#=GS T1J5Z0_STRMM/937-1109       AC T1J5Z0.1
#=GS L5KQC2_PTEAL/1024-1197      AC L5KQC2.1
#=GS F6U3P2_ORNAN/1032-1122      AC F6U3P2.1
#=GS E2BMN6_HARSA/1084-1240      AC E2BMN6.1
#=GS A0A096M2T4_POEFO/984-1154   AC A0A096M2T4.1
#=GS X1WJA8_ACYPI/1049-1219      AC X1WJA8.1
#=GS M3VUW7_FELCA/990-1163       AC M3VUW7.1
#=GS G1P8B5_MYOLU/993-1166       AC G1P8B5.1
#=GS PLCB1_MOUSE/1003-1176       AC Q9Z1B3.2
#=GS W5N5D4_LEPOC/1093-1258      AC W5N5D4.1
#=GS H2NMT9_PONAB/156-323        AC H2NMT9.2
#=GS PLCB2_RAT/976-1151          AC O89040.1
#=GS W5LF86_ASTMX/954-1126       AC W5LF86.1
#=GS H2T0J6_TAKRU/986-1121       AC H2T0J6.1
#=GS H2T0J5_TAKRU/1015-1173      AC H2T0J5.1
#=GS H2T5M2_TAKRU/896-1028       AC H2T5M2.1
#=GS F6VSL4_XENTR/965-1140       AC F6VSL4.1
#=GS G3NT25_GASAC/1067-1129      AC G3NT25.1
#=GS H2T0J4_TAKRU/1018-1176      AC H2T0J4.1
#=GS V8P4U0_OPHHA/54-92          AC V8P4U0.1
#=GS G1MFM0_AILME/942-1097       AC G1MFM0.1
#=GS H3CA47_TETNG/998-1148       AC H3CA47.1
#=GS H9GKW8_ANOCA/981-1156       AC H9GKW8.2
#=GS F7FSH8_CALJA/922-1071       AC F7FSH8.1
#=GS H2QJY4_PANTR/922-1095       AC H2QJY4.1
#=GS F7FSH1_CALJA/922-1095       AC F7FSH1.1
#=GS G1SSV4_RABIT/912-1060       AC G1SSV4.2
#=GS G3UBY5_LOXAF/890-1029       AC G3UBY5.1
#=GS H3APZ2_LATCH/924-1034       AC H3APZ2.1
#=GS H0X1B8_OTOGA/979-1155       AC H0X1B8.1
#=GS A0A096NVH5_PAPAN/412-585    AC A0A096NVH5.1
#=GS PLCB2_HUMAN/978-1153        AC Q00722.2
#=GS W4X425_ATTCE/1071-1209      AC W4X425.1
#=GS F7BGK4_XENTR/964-1133       AC F7BGK4.1
#=GS F6VVA6_ORNAN/926-1071       AC F6VVA6.2
#=GS M7ANH5_CHEMY/961-1136       AC M7ANH5.1
#=GS F6QQI2_CALJA/1025-1198      AC F6QQI2.1
#=GS L5JY32_PTEAL/972-1120       AC L5JY32.1
#=GS A0A096NTF5_PAPAN/978-1153   AC A0A096NTF5.1
#=GS B4LUP2_DROVI/1092-1236      AC B4LUP2.1
#=GS W5L6H5_ASTMX/1013-1185      AC W5L6H5.1
#=GS H0WUK0_OTOGA/922-1072       AC H0WUK0.1
#=GS H2T0J3_TAKRU/986-1158       AC H2T0J3.1
#=GS G3I883_CRIGR/1026-1199      AC G3I883.1
#=GS Q45QJ4_RAT/1031-1204        AC Q45QJ4.1
#=GS L9KMX3_TUPCH/923-1065       AC L9KMX3.1
#=GS W5M1N1_LEPOC/1-105          AC W5M1N1.1
#=GS E1BHX7_BOVIN/1029-1202      AC E1BHX7.1
#=GS B3SC96_TRIAD/960-1122       AC B3SC96.1
#=GS G1RVN2_NOMLE/922-1095       AC G1RVN2.1
#=GS F6SD46_MONDO/908-1085       AC F6SD46.1
#=GS A0A0D9R4V3_CHLSB/978-1153   AC A0A0D9R4V3.1
#=GS Q29N33_DROPS/1076-1227      AC Q29N33.2
#=GS L5JZQ0_PTEAL/46-90          AC L5JZQ0.1
#=GS G1N430_MELGA/670-808        AC G1N430.2
#=GS G3UDB8_LOXAF/984-1157       AC G3UDB8.1
#=GS H2M1G8_ORYLA/931-1104       AC H2M1G8.1
#=GS I3K795_ORENI/1001-1171      AC I3K795.1
#=GS H0YKR9_HUMAN/1-84           AC H0YKR9.1
#=GS A0A0D9R3U6_CHLSB/1032-1205  AC A0A0D9R3U6.1
#=GS H9H683_MONDO/741-879        AC H9H683.2
#=GS F1M084_RAT/922-1095         AC F1M084.3
#=GS H2Q3Z3_PANTR/1029-1202      AC H2Q3Z3.1
#=GS M3Y4V8_MUSPF/926-1076       AC M3Y4V8.1
#=GS E7F5Y6_DANRE/623-679        AC E7F5Y6.1
#=GS G1MWY7_MELGA/981-1156       AC G1MWY7.1
#=GS B4KL19_DROMO/1101-1253      AC B4KL19.1
#=GS H3AZ25_LATCH/981-1154       AC H3AZ25.2
#=GS G1QYG5_NOMLE/1029-1202      AC G1QYG5.1
#=GS E7FE48_DANRE/7-84           AC E7FE48.1
#=GS H2P106_PONAB/1002-1175      AC H2P106.1
#=GS W5NI42_LEPOC/1031-1177      AC W5NI42.1
#=GS I3IYR5_ORENI/973-1033       AC I3IYR5.1
#=GS F7GXA6_MACMU/987-1158       AC F7GXA6.1
#=GS PLCB1_HUMAN/1003-1176       AC Q9NQ66.1
#=GS F6QQW1_CALJA/996-1169       AC F6QQW1.1
#=GS A0A091DA99_FUKDA/970-1143   AC A0A091DA99.1
#=GS G1PB22_MYOLU/975-1150       AC G1PB22.1
#=GS W5N5E1_LEPOC/947-1122       AC W5N5E1.1
#=GS G5BLY4_HETGA/971-1146       AC G5BLY4.1
#=GS B0W1K0_CULQU/859-1012       AC B0W1K0.1
#=GS G1Q7E5_MYOLU/587-726        AC G1Q7E5.1
#=GS F7C4D9_XENTR/991-1164       AC F7C4D9.1
#=GS G5BAR9_HETGA/922-1095       AC G5BAR9.1
#=GS F6RJC0_MACMU/1031-1202      AC F6RJC0.1
#=GS G3R963_GORGO/1011-1184      AC G3R963.1
#=GS F7I202_CALJA/968-1143       AC F7I202.1
#=GS H0YNI4_HUMAN/1-42           AC H0YNI4.1
#=GS H9G588_ANOCA/1012-1185      AC H9G588.2
#=GS I3MR14_SPETR/1003-1176      AC I3MR14.1
#=GS F1SS34_PIG/896-1071         AC F1SS34.2
#=GS L9JC73_TUPCH/984-1159       AC L9JC73.1
#=GS A0A096N6P9_PAPAN/1029-1202  AC A0A096N6P9.1
#=GS F6SRN6_CIOIN/3-168          AC F6SRN6.2
#=GS G3T825_LOXAF/975-1129       AC G3T825.1
#=GS F6PJE1_HORSE/1016-1189      AC F6PJE1.1
#=GS G3R558_GORGO/922-1095       AC G3R558.1
#=GS U3I4B6_ANAPL/980-1091       AC U3I4B6.1
#=GS G6CJ81_DANPL/840-978        AC G6CJ81.1
#=GS H3C925_TETNG/961-1108       AC H3C925.1
#=GS D2HGF5_AILME/922-1095       AC D2HGF5.1
#=GS H3CWV7_TETNG/992-1156       AC H3CWV7.1
#=GS PLCB2_MOUSE/974-1149        AC A3KGF7.1
#=GS H2T006_TAKRU/971-1146       AC H2T006.1
#=GS H2T005_TAKRU/1013-1158      AC H2T005.1
#=GS W5QG18_SHEEP/999-1174       AC W5QG18.1
#=GS J9JHK9_CANFA/1025-1197      AC J9JHK9.1
#=GS F1SBL1_PIG/925-1064         AC F1SBL1.2
#=GS H2T008_TAKRU/1020-1184      AC H2T008.1
#=GS A0A087WT80_HUMAN/923-1096   AC A0A087WT80.1
#=GS A0A0D9RMA8_CHLSB/902-1075   AC A0A0D9RMA8.1
#=GS I3K2K1_ORENI/1079-1237      AC I3K2K1.1
#=GS H2T007_TAKRU/983-1152       AC H2T007.1
#=GS H0W8H6_CAVPO/1011-1183      AC H0W8H6.1
#=GS M3YNF2_MUSPF/1028-1201      AC M3YNF2.1
#=GS Q8IV91_HUMAN/1-41           AC Q8IV91.2
#=GS F6T8C1_HORSE/929-1077       AC F6T8C1.1
#=GS W5KF50_ASTMX/1015-1188      AC W5KF50.1
#=GS G3PDG8_GASAC/1004-1168      AC G3PDG8.1
#=GS V8P5W0_OPHHA/900-1043       AC V8P5W0.1
#=GS U3K8T0_FICAL/982-1123       AC U3K8T0.1
#=GS F6ZKL2_MACMU/1003-1176      AC F6ZKL2.1
#=GS J9P126_CANFA/902-1051       AC J9P126.1
#=GS G3WJX3_SARHA/1005-1178      AC G3WJX3.1
#=GS L5M8A3_MYODS/915-1088       AC L5M8A3.1
#=GS W5KF47_ASTMX/1015-1195      AC W5KF47.1
G3WSF5_SARHA/859-1006                  ..................................QKLVELKDKQQQQLLNLRQEQYYSEKYQKREH..................IKLL..IQKLTDVAEECQNNQLKKLKEICEK.EK.KELKKKMDKKRQEK.I..TEA.KSKDKS.QMEE.EKT--EMIRSYIQEVVQYIK..RLEDAQSKRQEKLLEKHKEIRQQILDEK.P.......K.-----....------------------------------gegsssyls..........
H0WVR1_OTOGA/1029-1202                 ..................................KRYQEFRNRQVQSLLELREAQADTEAERRLEH..................LKQV..QQRLREIVLEAHTAQFKRLKEMNER.EK.KELQKILDRKRHNS.I..SEA.KTREKH.K-KE.AELT-EINRRHITESVNSIR..RLEEAQKQRHDRLVAGQQQVLQQLAEEE.P.......K.LLAQL....AQECQEQRSRLPQEIRRSLLGETMEG----lgdr...............
F1PL90_CANFA/921-1094                  ..................................QKLIDLKDKQQQQLLNLRQEQYYSEKYQKREH..................IKLL..IQKLTDVAEECQNNQLKKLKEICEK.EK.KELKKKMDKKRQEK.I..TEA.KSKDKS.QMEE.EKT--EMIRSYIQEVVQYIK..RLEEAQSKRQEKLVEKHKEIRQQILDEK.P.......K.LQMDL....EQEYQDKFKRLPLEILEFVQEAMKGKIS--ee.................
G3GSB8_CRIGR/806-948                   ..................................QKLIDLKDKQQQQLLNLRQEQYYSEKYQKREH..................IKLL..IQKLTDVAEECQNNQLKKLKETCEK.EK.KELKKKMDKKRQEK.I..TEA.KSKDKS.QMEE.EKT--EMIRSYIQEVVQYIK..RLEEAQSKRQEKLVEKHKEIRQQILDEK.P.......K.V----....------------------------------nga................
M4A280_XIPMA/1035-1208                 ..................................QKLAELKEQQQQQLLKLRQEQYYSEKYLKREH..................IKQL..VEKLTTIAEECQSAQLKKIRDICEK.EK.KDLKKKMDKKRQEK.I..NEA.KTKDKN.LTEE.EKL--EINRSFVNEVVQYIK..RLEDAQCKRQERLQEKHKDTRQQILDEK.P.......K.LQSDL....DQEYQDKFRRLPVEIQEFVQDSSKTKLCD-d..................
A0A067RK16_ZOONE/820-961               ................................sk--AAGLPRSQSERLLSLCKDYINHEKELREKY..................HALI..FQTVEKLMKTSQCNQLKLLSALLER.ET.ADVMRRLEAVRRGE.V..KAL.SKVHRD.KDEM.IRIKREVASSMVEKGVHERV..RLTKIYEKRREELQRQHEEVRLSLEERK.H.......K.-----....------------------------------v..................
H2T5M1_TAKRU/1030-1169                 ..................................QRLAELKEQQQQQLLTLRQEQYYSEKYQKREH..................IKQL..VEKLTTIAEECQNIQLKKLKDICEK.EK.KDLKKRMDKKRQEK.I..SEA.KSKDKN.VTEE.EKL--EINRSFVNEVVQYIK..RLEDAQSKRQERLLEKHKDIRQQILDER.P.......K.-----....------------------------------v..................
G7PAX0_MACFA/864-1011                  .............................prsng--------------------------------..................-SPQ..ISKMMELAREKQAAELKALKETAEI.DT.KEMKKKLETKRLER.I..QGM.TKVTAD.KMAQ.ERLKREINSSHIQEVVQVIK..QMTENLEKHQEKLEEKQAACLEQIREME.K.......Q.FQKEA....LAEYEARMKGLEAEVKESVRACFRTCFPSE...................
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#=GC SS_cons                           ..................................HHHHHHHHHHHHHHHHHHHHHHHHTTTHHHHH..................---T..TTHHHHHHHHHHHHHHHHHHHHHHH.TH.HHHHHHHHHHHHHH.H..HHH.HHHHHH.H-HH.HTTT-GGGT--XXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXXX.X.......X.XXXXX....XXXXXXXXXXXXXXXXXXXXXXXXXXX---XXX................
#=GC seq_cons                          ...................................+hh-L+-cQpQpLLpLRpEQa.sEphp+ccH..................lcph..hpKLp-lAcEsQssQLK+LKEhsE+.EK.KELKKphD+KRp-c.I..spA.Ks+-Ks.phcp.E+l..Els+SaIpEsVphI+..RLEEsQp+RQE+LhccppplhQQIh--c.s.......+.hptph.....tEhptphttL..El.p.l.tt...........................
//
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