GenomeNet

Database: Pfam
Entry: PLRV_ORF5
LinkDB: PLRV_ORF5
Original site: PLRV_ORF5 
#=GF ID   PLRV_ORF5
#=GF AC   PF01690.15
#=GF DE   Potato leaf roll virus readthrough protein
#=GF AU   Bashton M, Bateman A
#=GF SE   Pfam-B_1335 (release 4.1)
#=GF GA   27.40 27.40;
#=GF TC   28.80 28.80;
#=GF NC   22.90 21.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   7513925
#=GF RT   Changes in the amino acid sequence of the coat protein
#=GF RT   readthrough domain of potato leafroll luteovirus affect the
#=GF RT   formation of an epitope and aphid transmission. 
#=GF RA   Jolly CA, Mayo MA; 
#=GF RL   Virology 1994;201:182-185.
#=GF DR   INTERPRO; IPR002929;
#=GF CC   This family consists mainly of the potato leaf roll virus 
#=GF CC   readthrough protein. This is generated via a readthrough  of
#=GF CC   open reading frame 3 a coat protein allowing transcription of
#=GF CC   open reading frame 5 to give an extended coat protein  with a
#=GF CC   large c-terminal addition or read through domain [1]. The
#=GF CC   readthrough protein is thought to play a role in the 
#=GF CC   circulative aphid transmission of potato leaf roll virus [1].
#=GF CC   Also in the family is open reading frame 6 from beet western
#=GF CC   yellows virus and potato leaf roll virus both luteovirus and an
#=GF CC   unknown protein from cucurbit aphid-borne yellows virus a
#=GF CC   closterovirus.
#=GF SQ   6
#=GS MCAPS_PLRV1/213-697   AC P17525.2
#=GS MCAPS_BYDVP/564-649   AC P09516.3
#=GS MCAPS_BYDVP/218-571   AC P09516.3
#=GS Q84829_PLRV1/5-489    AC Q84829.1
#=GS R9S4X7_SIMAS/215-306  AC R9S4X7.1
#=GS MCAPS_PEMVW/198-469   AC Q84711.2
MCAPS_PLRV1/213-697              ...SEPSPSPQPTPTPTPQK.HERFIAY...VGIPMLTIQARENDDQIILGSLGSQRMKYIEDENQNYTKFSSEYYSQSSMQAVPMYYFNVPKGQWSVDISCEGYQPTSSTSDPNRGRSDGMIAYSNADSDYWNVGEADGVKISKLRNDNTYRQGHPELEINSCHFREGQLLERDATISFHVEAP.TDGRFFLVGPAIQKTAKYNYTISYGDWTDRDMELGLITVVLDEHLEGTGSANRVRR....PPREGHTYMASPH.EPEGKPVGNKPRD.ETPIQTQ......ERQPDQTPSDDVSDAGSVNSGGPTESLRLEFGVNSDSTYDATVD.............GTDWPRIPPPRHPPEPRVSGNSRTVTDFSSKADLLENWDAEHFDPGYSKEDVAAATIIAHGSIQDGRSMLEKREENVKNKTSSWKPP....SLKAVSPAIAKLRSIRKSQPLEGGTLNK.......DATDGVSSIGSGSLTGGTLKRKATIEERLLQTLTTEQRLWYENFKKTNP.PAATQWLFEY..................................
MCAPS_BYDVP/564-649              edv-----------------.-------...----------------------------------------------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------....-------------.-------------.-------......--------------------------------------------.............-------------------------------------------------------------------------------------PPmarqKLREAANAPSTLLYERRTPKKSGNFLSRlveanrsPTTPTAPSVSTTS------------------NMTREQLREYTRIRNSSGiTAAKAYKAQF..................................
MCAPS_BYDVP/218-571              ...PQPTPAPQPTPEPTPAPvPKRFFEY...IGTPTGTISTRENTDSISVSKLGGQSMQYIENEKCETKVIDSFWSTNNNVSAQAAFVYPVPEGSYSVNISCEGFQSVDHIGGNEDGYWIGLIAYSNSSGDNWGVGNYKGCSFKNFLATNTWRPGHKDLKLTDCQFTDGQIVERDAVMSFHVEATgKDASFYLMAPKTMKTDKYNYVVSYGGYTNKRMEFGTISVTCD---ESDVEAERITRhaetPIRSKHILVSERYaEPLPTIVNQGLCDvKTPEQEQtlvdedDRQTVSTESDIA---------------LLEYEAATAEIPDAEEDvlpskeqlsskpmDTSGNIIPKPKEP-------------------EVLGTYQGQNIYP----EDV-----------------------------------....----------------------------.......-------------------------------------------------.----------ppmar.............................
Q84829_PLRV1/5-489               ...SEPSPSPQPTPTPTPQK.HERFIAY...VGIPMLTIQARENDDQIILGSLGSQRMKYIEDENQNYTKFSSEYYSQSSMQAVPMYYFNVPKGQWSVDISCEGYQPTSSTSDPNRGRSDGMIAYSNADSDYWNVGEADGVKISKLRNDNTYRQGHPELEINSCHFREGQLLERDATISFHVEAP.TDGRFFLVGPAIQKTAKYNYTISYGDWTDRDMELGLITVVLDEHLEGTGSANRVRR....PPREGHTYMASPH.EPEGKPVGNKPRD.ETPIQTQ......ERQPDQTPSDDVSDAGSVNSGGPTESLRLEFGVNSDSTYDATVD.............GTDWPRIPPPRHPPEPRVSGNSRTVTDFSSKADLLENWDAEHFDPGYSKEDVAAATIIAHGSIQDGRSMLEKREENVKNKTSSWKPP....SLKAVSPAIAKLRSIRKSQPLEGGTLNK.......DATDGVSSIGSGSLTGGTLKRKATIEERLLQTLTTEQRLWYENFKKTNP.PAATQWLFEY..................................
R9S4X7_SIMAS/215-306             ept--PTPEPTPTPEPTPSPaPEGPVSVagpVTVNWDAPATRENGDPIDVSELGGYEIRYREEGATDYTYV------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------....-------------.-------------.-------......--------------------------------------------.............---------------------------------------------------------------------------------------....----------------------------.......-------------------------------------------------.----------lvedgyalskyvgdlygsyefev...........
MCAPS_PEMVW/198-469              pgp-DPGPQPPPPPPPSPTPvGARFWGY...EGVPESRMISERNDHDIDVKPLSFITMYKWEDESWTSVKLSASYLQNDQVEATPYFLIPSSKGKFSVYIECEGFQAVKSIGGKSDGCWGGLIAY-NRKKDGWQARAYTGTVLSNYRSTTTVINGHPDCEVNDCKFKPDRGVESDLICSFHLEAE.EDSYWALQAPPIQKSSDYNYVVSYGGYTEKSIEWGSVSISID-EVNQTASASPWRG....RAR----------.-------------.-------......--------------------------------------------.............---------------------------------------------------------------------------------------....----------------------------.......-------------------------------------------------.----------klailqetavpppfppggvmdyhlgdregdqtgt
#=GC seq_cons                    ....pPoPpPpPTPpPTPp...cRFhuY...lGlPh.shtsRENsDpI.lupLGu.pMpYhE-Espshshhsu.a.ppsphpA.shahhssscGpaSV.IpCEGaQsspphus.pcGh..GhIAY.NtptD.WtstthpGs.hpphhsssThh.GH.-hclssCpFp.sphlEpDhhhSFHlEA..pDu.ahL.uP.h.KoscYNYslSYGsaTp+phEhG.lolshD...ptsspAp.hpt......R...........................................................................................................................................................................................................................................................................................................................
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