GenomeNet

Database: Pfam
Entry: PP1_inhibitor
LinkDB: PP1_inhibitor
Original site: PP1_inhibitor 
#=GF ID   PP1_inhibitor
#=GF AC   PF05361.8
#=GF DE   PKC-activated protein phosphatase-1 inhibitor
#=GF AU   Finn RD
#=GF SE   Pfam-B_69711 (release 7.8)
#=GF GA   20.70 20.70;
#=GF TC   20.70 20.70;
#=GF NC   20.60 20.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11734001
#=GF RT   Solution NMR structure of the myosin phosphatase inhibitor
#=GF RT   protein CPI-17 shows phosphorylation-induced conformational
#=GF RT   changes responsible for activation. 
#=GF RA   Ohki S, Eto M, Kariya E, Hayano T, Hayashi Y, Yazawa M,
#=GF RA   Brautigan D, Kainosho M; 
#=GF RL   J Mol Biol 2001;314:839-849.
#=GF DR   INTERPRO; IPR008025;
#=GF DR   SCOP; 1k5o; fa;
#=GF CC   Contractility of vascular smooth muscle depends on
#=GF CC   phosphorylation of myosin light chains, and is modulated by
#=GF CC   hormonal control of myosin phosphatase activity. Signaling
#=GF CC   pathways activate kinases such as PKC or Rho-dependent kinases
#=GF CC   that phosphorylate the myosin phosphatase inhibitor protein
#=GF CC   called CPI-17. Phosphorylation of CPI-17 at Thr-38 enhances its
#=GF CC   inhibitory potency 1000-fold, creating a molecular switch for
#=GF CC   regulating contraction [1].
#=GF SQ   358
#=GS H0VQA4_CAVPO/25-146      AC H0VQA4.1
#=GS G3UIU2_LOXAF/1-119       AC G3UIU2.1
#=GS B5MC51_HUMAN/519-629     AC B5MC51.1
#=GS G3PAR8_GASAC/38-143      AC G3PAR8.1
#=GS W5KGT9_ASTMX/12-150      AC W5KGT9.1
#=GS W5NH63_LEPOC/30-141      AC W5NH63.1
#=GS M3ZWL2_XIPMA/6-125       AC M3ZWL2.1
#=GS G3HJA1_CRIGR/172-243     AC G3HJA1.1
#=GS U6HDR6_ECHMU/2-91        AC U6HDR6.1
#=GS M3Z2C2_MUSPF/1-113       AC M3Z2C2.1
#=GS Q5DEP4_SCHJA/15-137      AC Q5DEP4.1
#=GS F7H6G2_CALJA/37-164      AC F7H6G2.1
#=GS F6T2P4_MACMU/93-156      AC F6T2P4.1
#=GS I3IVJ1_ORENI/32-141      AC I3IVJ1.1
#=GS W5QGE0_SHEEP/32-151      AC W5QGE0.1
#=GS H9GBT4_ANOCA/1-64        AC H9GBT4.1
#=GS F6Q451_CALJA/39-147      AC F6Q451.1
#=GS J9APU5_WUCBA/1-60        AC J9APU5.1
#=GS G3TNN7_LOXAF/23-145      AC G3TNN7.1
#=GS G3Q899_GASAC/21-139      AC G3Q899.1
#=GS V9KNK8_CALMI/22-136      AC V9KNK8.1
#=GS B0WBN1_CULQU/4-123       AC B0WBN1.1
#=GS G7MZL1_MACMU/27-137      AC G7MZL1.1
#=GS H3BAE8_LATCH/1-141       AC H3BAE8.1
#=GS A0A016UXK2_9BILA/1-87    AC A0A016UXK2.1
#=GS G3VPI7_SARHA/1-62        AC G3VPI7.1
#=GS V9LDM5_CALMI/3-115       AC V9LDM5.1
#=GS T2M885_HYDVU/10-120      AC T2M885.1
#=GS G1SP96_RABIT/24-145      AC G1SP96.1
#=GS C1BMC3_OSMMO/1-120       AC C1BMC3.1
#=GS K7FY66_PELSI/28-146      AC K7FY66.1
#=GS R4G9M6_ANOCA/1-142       AC R4G9M6.1
#=GS G8F528_MACFA/93-156      AC G8F528.1
#=GS W5NM54_LEPOC/6-66        AC W5NM54.1
#=GS U3JUF6_FICAL/5-129       AC U3JUF6.1
#=GS G1NJ36_MELGA/1-64        AC G1NJ36.2
#=GS F7GNA1_MACMU/1-45        AC F7GNA1.1
#=GS H9JZY1_APIME/4-126       AC H9JZY1.1
#=GS PP14D_RAT/21-143         AC Q8K3F4.1
#=GS F6T9E6_CALJA/1-136       AC F6T9E6.1
#=GS F6YMT9_HORSE/1-90        AC F6YMT9.1
#=GS V9LKU0_CALMI/3-119       AC V9LKU0.1
#=GS PP14B_HUMAN/39-147       AC Q96C90.3
#=GS W5KIW0_ASTMX/1-129       AC W5KIW0.1
#=GS PP14A_MOUSE/1-136        AC Q91VC7.1
#=GS F7ISZ2_CALJA/24-145      AC F7ISZ2.1
#=GS G1RZH1_NOMLE/37-165      AC G1RZH1.1
#=GS H2LLB2_ORYLA/10-128      AC H2LLB2.1
#=GS G3TMV5_LOXAF/40-147      AC G3TMV5.1
#=GS U3J9G3_ANAPL/6-136       AC U3J9G3.1
#=GS H3D9R5_TETNG/2-136       AC H3D9R5.1
#=GS G3RNV8_GORGO/24-145      AC G3RNV8.1
#=GS G7PXF8_MACFA/1-97        AC G7PXF8.1
#=GS A0A016UZ39_9BILA/1-96    AC A0A016UZ39.1
#=GS G9KI59_MUSPF/30-150      AC G9KI59.1
#=GS Q9VKQ5_DROME/4-124       AC Q9VKQ5.1
#=GS A8RU10_CLOBW/3-55        AC A8RU10.1
#=GS PP14B_MOUSE/39-147       AC Q62084.2
#=GS H3B0M7_LATCH/6-127       AC H3B0M7.1
#=GS I3K793_ORENI/17-136      AC I3K793.1
#=GS Q640Z5_XENLA/28-156      AC Q640Z5.1
#=GS Q7ZZ24_DANRE/1-61        AC Q7ZZ24.1
#=GS U3EMJ9_CALJA/38-166      AC U3EMJ9.1
#=GS G1MIW0_AILME/1-108       AC G1MIW0.1
#=GS PP14A_HUMAN/1-139        AC Q96A00.1
#=GS PP14D_HUMAN/24-145       AC Q9NXH3.1
#=GS G3Q9T0_GASAC/2-137       AC G3Q9T0.1
#=GS Q4S430_TETNG/10-128      AC Q4S430.1
#=GS F7CUW3_XENTR/6-127       AC F7CUW3.1
#=GS U6CNZ7_NEOVI/23-145      AC U6CNZ7.1
#=GS R0KGE0_ANAPL/153-197     AC R0KGE0.1
#=GS Q4SB61_TETNG/1-136       AC Q4SB61.1
#=GS C1L4A3_SCHJA/15-140      AC C1L4A3.1
#=GS V9LK49_CALMI/9-125       AC V9LK49.1
#=GS L8IMB7_9CETA/56-129      AC L8IMB7.1
#=GS W5JBN9_ANODA/5-123       AC W5JBN9.1
#=GS I3MYR4_SPETR/36-142      AC I3MYR4.1
#=GS W5P696_SHEEP/1-119       AC W5P696.1
#=GS I3LZL5_SPETR/1-107       AC I3LZL5.1
#=GS G1TVU9_RABIT/1-105       AC G1TVU9.1
#=GS Q14BX6_MOUSE/38-153      AC Q14BX6.1
#=GS F6TJM9_CALJA/67-110      AC F6TJM9.1
#=GS G1P2P3_MYOLU/23-145      AC G1P2P3.1
#=GS M7AMN9_CHEMY/61-146      AC M7AMN9.1
#=GS F5GXC4_HUMAN/1-45        AC F5GXC4.1
#=GS K7CXC3_PANTR/40-154      AC K7CXC3.1
#=GS A8NFU7_BRUMA/2-119       AC A8NFU7.2
#=GS F6XG02_MACMU/1-22        AC F6XG02.1
#=GS L5LDG6_MYODS/29-97       AC L5LDG6.1
#=GS K7BUR7_PANTR/37-165      AC K7BUR7.1
#=GS F6SZL7_MONDO/28-148      AC F6SZL7.1
#=GS S7N667_MYOBR/1-133       AC S7N667.1
#=GS D2H4T9_AILME/25-133      AC D2H4T9.1
#=GS F1NQV6_CHICK/73-207      AC F1NQV6.2
#=GS Q29KQ3_DROPS/2-123       AC Q29KQ3.1
#=GS F6TA78_CALJA/1-128       AC F6TA78.1
#=GS Q7YX00_CAEEL/5-112       AC Q7YX00.1
#=GS A0A016UWD5_9BILA/1-71    AC A0A016UWD5.1
#=GS H2R706_PANTR/579-684     AC H2R706.1
#=GS F6ZGW6_HORSE/1-81        AC F6ZGW6.1
#=GS W5NPN6_SHEEP/13-107      AC W5NPN6.1
#=GS H9G7F4_ANOCA/19-148      AC H9G7F4.2
#=GS K7EJB8_HUMAN/1-116       AC K7EJB8.1
#=GS H2MPY2_ORYLA/26-136      AC H2MPY2.1
#=GS G7MWP5_MACMU/24-89       AC G7MWP5.1
#=GS E9PAT1_HUMAN/24-89       AC E9PAT1.1
#=GS M3YG61_MUSPF/33-109      AC M3YG61.1
#=GS Q28G89_XENTR/13-129      AC Q28G89.1
#=GS F1PCV4_CANFA/39-147      AC F1PCV4.2
#=GS T1E2M6_9DIPT/5-123       AC T1E2M6.1
#=GS V9LE51_CALMI/1-126       AC V9LE51.1
#=GS I2CUS4_MACMU/37-165      AC I2CUS4.1
#=GS U3KCG3_FICAL/2-70        AC U3KCG3.1
#=GS F6TJM9_CALJA/1-69        AC F6TJM9.1
#=GS I3MQH8_SPETR/18-140      AC I3MQH8.1
#=GS F7BC28_XENTR/28-153      AC F7BC28.1
#=GS I3KKU4_ORENI/1-108       AC I3KKU4.1
#=GS B4Q9T3_DROSI/4-124       AC B4Q9T3.1
#=GS Q0P4A9_DANRE/1-129       AC Q0P4A9.1
#=GS F6Y6N5_ORNAN/1-89        AC F6Y6N5.1
#=GS H2UV74_TAKRU/39-146      AC H2UV74.1
#=GS G9KI57_MUSPF/38-145      AC G9KI57.1
#=GS G7NCJ1_MACMU/93-156      AC G7NCJ1.1
#=GS T1H7V0_RHOPR/1-55        AC T1H7V0.1
#=GS T1L0E3_TETUR/2-92        AC T1L0E3.1
#=GS C1BWF8_ESOLU/2-123       AC C1BWF8.1
#=GS PP14B_RAT/39-147         AC Q8K3F3.1
#=GS A0A023F903_TRIIF/5-127   AC A0A023F903.1
#=GS S9X907_9CETA/2-113       AC S9X907.1
#=GS F7DZ04_CALJA/37-165      AC F7DZ04.1
#=GS Q29VH5_DANRE/2-136       AC Q29VH5.1
#=GS R0KVX3_ANAPL/5-112       AC R0KVX3.1
#=GS G1Q788_MYOLU/1-131       AC G1Q788.1
#=GS B4JE51_DROGR/45-167      AC B4JE51.1
#=GS G1MI51_AILME/40-148      AC G1MI51.1
#=GS Q3TMQ9_MOUSE/1-85        AC Q3TMQ9.1
#=GS U6D2E4_NEOVI/1-87        AC U6D2E4.1
#=GS L8I1J9_9CETA/23-144      AC L8I1J9.1
#=GS Q4RZ73_TETNG/1-135       AC Q4RZ73.1
#=GS W7UAB5_9STRA/34-161      AC W7UAB5.1
#=GS G4V8M7_SCHMA/8-125       AC G4V8M7.1
#=GS G3Q897_GASAC/11-128      AC G3Q897.1
#=GS M4ATZ5_XIPMA/1-141       AC M4ATZ5.1
#=GS S4RJC1_PETMA/19-142      AC S4RJC1.1
#=GS B4GSZ8_DROPE/2-123       AC B4GSZ8.1
#=GS F7DGQ5_HORSE/23-145      AC F7DGQ5.1
#=GS H2L400_ORYLA/1-139       AC H2L400.1
#=GS W5P5T6_SHEEP/41-147      AC W5P5T6.1
#=GS M7AMN9_CHEMY/4-65        AC M7AMN9.1
#=GS G3WTH4_SARHA/28-148      AC G3WTH4.1
#=GS T1DQU0_ANOAQ/5-123       AC T1DQU0.1
#=GS H2WGE8_CAEJA/5-112       AC H2WGE8.1
#=GS A0A022T2W0_9HYME/7-126   AC A0A022T2W0.1
#=GS B4HWV3_DROSE/4-124       AC B4HWV3.1
#=GS J9P3B5_CANFA/1-68        AC J9P3B5.1
#=GS M4A4Y5_XIPMA/40-149      AC M4A4Y5.1
#=GS G9KI56_MUSPF/1-65        AC G9KI56.1
#=GS Q4KMJ9_DANRE/21-134      AC Q4KMJ9.1
#=GS E9FR70_DAPPU/11-139      AC E9FR70.1
#=GS A0A024R563_HUMAN/92-199  AC A0A024R563.1
#=GS H2SY42_TAKRU/1-143       AC H2SY42.1
#=GS V9LKN2_CALMI/8-114       AC V9LKN2.1
#=GS G8XXX3_OREMO/1-81        AC G8XXX3.1
#=GS G3ICK0_CRIGR/18-89       AC G3ICK0.1
#=GS Q66KC0_XENTR/1-138       AC Q66KC0.1
#=GS G1S4X8_NOMLE/1-139       AC G1S4X8.1
#=GS B3MJV5_DROAN/4-124       AC B3MJV5.1
#=GS U6IHJ4_HYMMI/3-101       AC U6IHJ4.1
#=GS G3SB74_GORGO/3-116       AC G3SB74.1
#=GS N6UBV8_DENPD/19-132      AC N6UBV8.1
#=GS A4QP76_DANRE/7-122       AC A4QP76.1
#=GS G1QC33_MYOLU/48-171      AC G1QC33.1
#=GS E2RES0_CANFA/31-150      AC E2RES0.2
#=GS G1NF46_MELGA/27-159      AC G1NF46.1
#=GS T1J181_STRMM/18-142      AC T1J181.1
#=GS Q641W6_RAT/31-147        AC Q641W6.1
#=GS W5KP38_ASTMX/13-156      AC W5KP38.1
#=GS Q6GNL2_XENLA/13-129      AC Q6GNL2.1
#=GS F6Q2M3_HORSE/2-112       AC F6Q2M3.1
#=GS R4G3R2_RHOPR/3-127       AC R4G3R2.1
#=GS I1FA42_AMPQE/1-118       AC I1FA42.1
#=GS H2PKM0_PONAB/19-90       AC H2PKM0.1
#=GS A0A016UX18_9BILA/1-62    AC A0A016UX18.1
#=GS B4KKN4_DROMO/4-124       AC B4KKN4.1
#=GS A5PK48_BOVIN/23-144      AC A5PK48.1
#=GS D2HTH8_AILME/1-124       AC D2HTH8.1
#=GS H2L405_ORYLA/1-137       AC H2L405.1
#=GS A0A023EEQ4_AEDAL/4-110   AC A0A023EEQ4.1
#=GS F1S7V6_PIG/37-165        AC F1S7V6.1
#=GS H2U8C0_TAKRU/4-126       AC H2U8C0.1
#=GS Q8BUV2_MOUSE/1-33        AC Q8BUV2.1
#=GS H0UZP4_CAVPO/1-85        AC H0UZP4.1
#=GS H0X246_OTOGA/1-136       AC H0X246.1
#=GS E1B7I6_BOVIN/26-142      AC E1B7I6.2
#=GS G5BM01_HETGA/23-91       AC G5BM01.1
#=GS L8IJZ3_9CETA/25-134      AC L8IJZ3.1
#=GS Q7ZZ37_DANRE/4-128       AC Q7ZZ37.1
#=GS U6DWX3_NEOVI/1-81        AC U6DWX3.1
#=GS G3QT63_GORGO/24-89       AC G3QT63.1
#=GS C5EPD7_9FIRM/3-55        AC C5EPD7.1
#=GS W5U8D1_ICTPU/1-139       AC W5U8D1.1
#=GS E1C0X7_CHICK/29-148      AC E1C0X7.2
#=GS H2R1S8_PANTR/37-165      AC H2R1S8.1
#=GS Q0VCI8_BOVIN/41-168      AC Q0VCI8.1
#=GS L9JC38_TUPCH/17-148      AC L9JC38.1
#=GS G3UM52_LOXAF/1-130       AC G3UM52.1
#=GS V9LDU2_CALMI/6-115       AC V9LDU2.1
#=GS H3DFW4_TETNG/34-143      AC H3DFW4.1
#=GS G6D1C0_DANPL/133-190     AC G6D1C0.1
#=GS W6V135_ECHGR/3-102       AC W6V135.1
#=GS H0VVT5_CAVPO/1-64        AC H0VVT5.1
#=GS Q4V755_HUMAN/1-45        AC Q4V755.1
#=GS L9JP28_TUPCH/1-78        AC L9JP28.1
#=GS G3X024_SARHA/46-173      AC G3X024.1
#=GS H3D652_TETNG/22-141      AC H3D652.1
#=GS W5UEW2_ICTPU/33-141      AC W5UEW2.1
#=GS M7BJZ3_CHEMY/1-103       AC M7BJZ3.1
#=GS H2NMV7_PONAB/24-145      AC H2NMV7.1
#=GS B3N537_DROER/4-124       AC B3N537.1
#=GS I0FWJ4_MACMU/1-139       AC I0FWJ4.1
#=GS L5KNJ1_PTEAL/1-134       AC L5KNJ1.1
#=GS B7PSA9_IXOSC/1-55        AC B7PSA9.1
#=GS G9KI58_MUSPF/1-74        AC G9KI58.1
#=GS E2RC84_CANFA/37-140      AC E2RC84.1
#=GS I3K2I7_ORENI/3-122       AC I3K2I7.1
#=GS G3N903_GASAC/1-138       AC G3N903.1
#=GS U6JE53_ECHGR/2-91        AC U6JE53.1
#=GS B4MU57_DROWI/4-124       AC B4MU57.1
#=GS T0MDQ8_9CETA/48-143      AC T0MDQ8.1
#=GS V9LJB7_CALMI/13-128      AC V9LJB7.1
#=GS K7EMN0_HUMAN/1-95        AC K7EMN0.1
#=GS PP14D_MOUSE/22-143       AC Q7TT52.2
#=GS G3TFA0_LOXAF/37-166      AC G3TFA0.1
#=GS D2GW97_AILME/23-145      AC D2GW97.1
#=GS W5NY86_SHEEP/1-64        AC W5NY86.1
#=GS PP14C_MOUSE/36-164       AC Q8R4S0.1
#=GS Q0IHD5_XENLA/12-129      AC Q0IHD5.1
#=GS T1P9U5_MUSDO/4-124       AC T1P9U5.1
#=GS A0A034VTY0_BACDO/5-124   AC A0A034VTY0.1
#=GS L8HVD0_9CETA/5-65        AC L8HVD0.1
#=GS F6RDK6_MACMU/39-108      AC F6RDK6.1
#=GS M4A2I6_XIPMA/10-128      AC M4A2I6.1
#=GS G5AMC3_HETGA/15-94       AC G5AMC3.1
#=GS W5LF96_ASTMX/8-127       AC W5LF96.1
#=GS V9LEN8_CALMI/3-120       AC V9LEN8.1
#=GS S4RYZ1_PETMA/14-151      AC S4RYZ1.1
#=GS G3RYU7_GORGO/44-149      AC G3RYU7.1
#=GS U5EQV0_9DIPT/5-123       AC U5EQV0.1
#=GS A8Y4I0_CAEBR/5-112       AC A8Y4I0.1
#=GS M3YP53_MUSPF/37-145      AC M3YP53.1
#=GS S9WX33_9CETA/6-67        AC S9WX33.1
#=GS G1QYA5_NOMLE/39-147      AC G1QYA5.1
#=GS F6Y7A1_CANFA/52-174      AC F6Y7A1.1
#=GS V9LJY3_CALMI/1-135       AC V9LJY3.1
#=GS M7CFF9_CHEMY/3-104       AC M7CFF9.1
#=GS H2RF42_PANTR/39-147      AC H2RF42.1
#=GS Q4RRA1_TETNG/169-235     AC Q4RRA1.1
#=GS C3Y0Q5_BRAFL/4-62        AC C3Y0Q5.1
#=GS G3R934_GORGO/41-87       AC G3R934.1
#=GS G3QTH2_GORGO/1-139       AC G3QTH2.1
#=GS I3KFM0_ORENI/2-136       AC I3KFM0.1
#=GS G7PAX8_MACFA/1-45        AC G7PAX8.1
#=GS E3MQD0_CAERE/5-112       AC E3MQD0.1
#=GS H9YV07_MACMU/39-147      AC H9YV07.1
#=GS F1LVP5_RAT/5-82          AC F1LVP5.2
#=GS G1PXW0_MYOLU/38-166      AC G1PXW0.1
#=GS U6D543_NEOVI/1-94        AC U6D543.1
#=GS W8C4G5_CERCA/4-124       AC W8C4G5.1
#=GS G3I882_CRIGR/48-121      AC G3I882.1
#=GS G1LVE6_AILME/1-134       AC G1LVE6.1
#=GS M7B7W8_CHEMY/45-104      AC M7B7W8.1
#=GS B4P0U2_DROYA/4-124       AC B4P0U2.1
#=GS H0WGL9_OTOGA/23-145      AC H0WGL9.1
#=GS F7CDX3_MACMU/34-147      AC F7CDX3.1
#=GS G1QWE3_NOMLE/574-684     AC G1QWE3.1
#=GS H9FAP1_MACMU/30-138      AC H9FAP1.1
#=GS C3Y0Q5_BRAFL/82-149      AC C3Y0Q5.1
#=GS F6SCU8_MONDO/1-72        AC F6SCU8.1
#=GS F6XG02_MACMU/20-67       AC F6XG02.1
#=GS G7NMX1_MACMU/1-125       AC G7NMX1.1
#=GS B9EN08_SALSA/3-122       AC B9EN08.1
#=GS K7AYU7_PANTR/1-139       AC K7AYU7.1
#=GS G3SF11_GORGO/2-117       AC G3SF11.1
#=GS H0VEG1_CAVPO/1-120       AC H0VEG1.1
#=GS F7G690_MONDO/225-351     AC F7G690.2
#=GS PP14B_PIG/39-147         AC Q8MIK9.1
#=GS PP14A_RAT/1-132          AC Q99MC0.1
#=GS PP14A_PIG/1-132          AC O18734.1
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H0VQA4_CAVPO/25-146                 ...................................wtaerr--------RRTSSTDSESKs.....hTD.P..CR.LA.......R..S..RR...H..SR.LTVKYD...LGQL...QR...WLEMEQWVDAQIQELFQ.......D..Q.....A..E...P.......S.EP.......E.....I..DLE.TLLELSTEEQKM....-....QL.EGIL...Q..N....C...P...R...P...TE..D...FISELLSQLKKLRR------------------------lsrpqk........................
G3UIU2_LOXAF/1-119                  .........................................MAAQRLGKRVLSKLQAP--.......--.-..--.--.......L..Q..KR...H..AR.VTVKYD...RREL...QR...RLDVEKWIDGRLEELYR.......G..R.....E..A...E.......M.PD.......E.....V..NID.ELLELESEEERS....R....KV.RGLL...K..S....C...S...K...P...TE..D...FVQELLGKLRGLHKQP----------------------ghhqlspsg.....................
B5MC51_HUMAN/519-629                ...........................agegpgcaddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTIKYD...PKEL...RK...HLNLEEWILEQLTRLYD.......C..Q.....E..E...E.......I.SE......lE.....I..DVD.ELLDMESDDAWA....S....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRAMQKLST---------------------pqkk..........................
G3PAR8_GASAC/38-143                 ..................................pistgdd-------------------.......--.-..--.-P.......V..Q..RR...Q..GK.VTVKYD...RKEL...RK...RLVLEEWIIEQLSELYD.......C..E.....E..E...E.......M.PE......vE.....I..DID.DLLEVTSDDERA....S....KL.QESL...T..D....C...Y...K...P...TE..V...FVRELLGRIRGMRKL-----------------------saptk.........................
W5KGT9_ASTMX/12-150                 .......................................ma-EEQNGGRREEDGERLFPR.......--.-..AA.LS.......A..Q..KR...Q..SR.VTVKYN...RKEL...QK...RLDVETWIEEALEELYA.......G..L.....E..D...E.......M.PD.......E.....I..DID.ELLVLQSDEERV....Q....KI.QELL...Q..T....C...T...N...S...TQ..A...FITELLQKLHGLQKQEELQNKGIGHPCLHSYPHHHGN-v.............................
W5NH63_LEPOC/30-141                 .................................tgagperr-------------------.......--.-..-D.DS.......V..Q..KK...Q..GK.VTVKYD...RKEL...RK...RLILEEWIIEQLSELYD.......C..E.....E..E...E.......M.PE......vE.....I..DID.DLLDEPSEDERA....T....KL.QESL...I..D....C...Y...K...P...TE..E...FVKELLSRIRGMRKLSAPQKKGL---------------..............................
M3ZWL2_XIPMA/6-125                  ...................................amatep------GTQSRVMFQAPDK.......TE.D..--.-S.......A..H..RK...L..GK.LTVKYN...RKDL...QR...RLDIEEWIDGQLHLLFD.......C..E.....E..E...E.......I.PE......lE.....I..DID.ELLELPDEGQRT....-....RL.EELL...Q..E....C...G...K...P...KE..E...FINGLLYRIKGLRKM-----------------------sgplk.........................
G3HJA1_CRIGR/172-243                ...................................dlttid-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..L.....E..S...D.......M.PD.......E.....V..NID.ELLELDSEEERS....R....KI.QD--...-..-....-...-...-...-...--..-...FIQELLAKLRGLHKQPGFPQPSLTDDC-----------slsphqdrah....................
U6HDR6_ECHMU/2-91                   ....................sgkheitpkvnfpdivedetp-------------------.......--.-..--.--.......T..H..KR...H..--.LTARYDkktRRLM...RE...KLNLEDFIYAELRKVYL.......R..D.....D..D...E.......W.DC.......E.....I..DVD.QLIRLNES----....-....--.----...-..-....-...-...-...-...--..-...--------------------------------------grkayievtfe...................
M3Z2C2_MUSPF/1-113                  .................................xrargpgg-------------------.......--.-..--.-Sp....ggL..Q..KR...H..AR.VTVKYD...RREL...QR...RLDVEKWIDGRLEELYR.......G..R.....E..A...D.......M.PD.......E.....V..NID.ELLELESEEDRS....R....KI.QGLL...K..S....C...R...N...P...TE..D...FIQELLGKLRGLHKQPGLR-------------------ppsps.........................
Q5DEP4_SCHJA/15-137                 .......................lsketnehsdgfsqksvn--------------REVVF.......AT.D..AP.SD.......H..S..KR...K..RY.LTAKYD...RRTR...QKiseKIKIENFVFDQLRALYS.......T..E.....I..D...D.......Y.DC.......D.....I..DVD.EISDLETNEEKI....R....VL.KEKL...K..S....C...ParpE...E...IE..E...FIQSLLRRLK----------------------------..............................
F7H6G2_CALJA/37-164                 ....................ssgsgsswedsapvattaaag-------------------.......--.-..QV.QQ.......Q..Q..RRrhqQ..GK.VTVKYD...RKEL...RK...QLVLEEWILEQLGQLYG.......C..E.....E..E...E.......V.PE......vE.....T..DID.DLLDADSDEERA....S....KL.QEAL...V..D....C...S...K...P...TE..E...FIKELLSRIRGMRKLS----------------------ppqkks........................
F6T2P4_MACMU/93-156                 .......................................pp-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDARA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
I3IVJ1_ORENI/32-141                 .................................sgpinged-------------------.......--.-..--.-P.......V..Q..KK...Q..GK.VTVKYD...RKEL...RK...RLVLEEWIIEQLSVLYD.......C..E.....E..E...E.......M.PE......vE.....I..DID.DLLEVNSDDERA....S....KL.QESL...I..D....C...Y...K...P...TE..N...FVRELLGRIRGMRKLSAPTKKG----------------l.............................
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H9GBT4_ANOCA/1-64                   .........................................-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..Q.....E..E...E.......M.PD......vE.....I..DID.DLLDAANEEERA....I....KL.QEAL...V..D....C...Y...K...P...TE..D...FIKELLTRIKGMRKLSPPQKK-----------------si............................
F6Q451_CALJA/39-147                 .............................egpggaddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWILEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDARA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
J9APU5_WUCBA/1-60                   .......................................ml-------------------.......--.-..--.--.......-..-..--...-..--.-TMKYG...KHQMmliKK...RMNVEGWIDDQLNELYK.......S..A.....T..D...N.......I.--.......D.....I..DVD.AILDLNTELERR....H....Y-.----...-..-....-...-...-...-...--..-...--------------------------------------im............................
G3TNN7_LOXAF/23-145                 .....................................vqws-----SGRRRTSSTDSESK......pHP.D..PS.KV......pR..S..RR...P..SR.LTVKYD...RGQL...QR...WVEMEQWVDAQVQELFQ.......D..Q.....P..A...L.......S.EP.......E.....I..DLE.ALMELPTEEQK-....T....HL.EAIL...Q..N....C...P...R...P...TE..S...FISELLSQLKKLRR------------------------lsrpqk........................
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V9KNK8_CALMI/22-136                 ........................pprvffqlpgcsqdppg-------------------.......--.-..--.--.......-..Q..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWIIQQLHHLYD.......C..D.....E..E...E.......M.PE......lE.....I..DID.DLLDVSRDEDRA....L....KL.QESL...V..D....C...Y...K...P...TE..V...FVKELLDRIRGMRKLSA---------------------pqkk..........................
B0WBN1_CULQU/4-123                  ....................gvetmndcerspgrtglrvnf-------------------.......-T.E..KG.EV.......K..E..RR...E..KF.LTAKYG...SHQMsliRK...RLAVEMWLYDELQKLYD.......P..P.....T..E...A.......I.--.......D.....V..DID.EILDMDTDDIRR....S....HL.FSLL...S..A....C...KrppQ...D...IS..K...FISDLLDRAK----------------------------tl............................
G7MZL1_MACMU/27-137                 ...........................agegpsgaddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWIQEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDARA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
H3BAE8_LATCH/1-141                  .........................................MAANKVGKRAQNKFLSPSR.......NR.E..AG.LA.......V..Q..KR...Q..AR.VTVKYD...RKEL...QK...RLDVEKWIDERLEELYL.......G..R.....E..K...E.......M.PE.......E.....L..NID.DLLDLASDEERS....R....KL.KDML...H..S....C...N...S...N...IE..E...FTTELLIKLHGLPKQNVLQRNGIEHQEVEQFEELPGS-n.............................
A0A016UXK2_9BILA/1-87               ...............................mkygkqqmml-------------------.......--.-..--.--.......-..-..--...-..--.------...---I...RK...RMKIENWIDAEVAKLFN.......G..N.....D..N...N.......G.V-.......D.....I..DVD.VLLDLDSVPAKR....K....FV.FDNL...Q..Rs..hC...P...A...SmdkIT..M...FLDEMIDQLN----------------------------tl............................
G3VPI7_SARHA/1-62                   .........................................-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMETDSTRA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISDLLDKIRGMQKLST---------------------pqkk..........................
V9LDM5_CALMI/3-115                  ..................................sggsggs-------------------.......--.-..--.GT.......A..P..RR...Q..AR.VTVKYD...RRGL...QH...RLDVEKWIEDSVCQLYR.......E..Q.....E..D...E.......M.PE.......E.....V..NID.DLLELETDQERT....N....QL.QILF...A..S....C...N...R...N...TD..V...FIGELVTKLEGLHKAKTMQRVGQEV-------------rq............................
T2M885_HYDVU/10-120                 ........................ilrfngvnespsfskky-------------------.......--.-..--.--.......-..-..--...-..-A.ATAKYN...RKTL...SM...RLELEEWMHDQLRKLYN.......C..Qs...eD..D...D.......Y.NV.......E.....V..DVD.VLLAEEKSEVRF....K....ML.QELL...H..G....A...K...E...S...PE..S...FIDELLIRIRKLEN------------------------aplkkga.......................
G1SP96_RABIT/24-145                 ...................................qwtser-------RRRTSSTDSESR.......SH.S..DP.SR.......VprS..RR...S..SR.LTVKYD...LGQL...QR...WLEMEQWVDAQIQELFQ.......D..E.....S..V...T.......A.DI.......E.....I..DLE.ALMELSTEEQKT....-....QL.EDLL...R..N....C...P...R...P...TE..P...FISELLSQLKKFR-------------------------rlsrpq........................
C1BMC3_OSMMO/1-120                  ...........................matqsgpqgrvlfq---------------TPEE.......-K.E..EE.EP.......S..Q..RR...L..GK.LTVKYN...RKDL...QR...RLDIEEWIDGQLHLLFD.......C..E.....E..E...D.......I.PE......lG.....I..DID.ELLDLSNSEQRL....-....KL.YELL...Q..E....C...G...K...P...RE..D...FINGLLYRIKGLRKM-----------------------sgpl..........................
K7FY66_PELSI/28-146                 .....................gprvyfqnppgepgqeeeeg-------------------.......--.-..--.--.......P..G..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWILEQLTQLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMGSDEARG....A....RV.KELL...V..D....C...Y...K...P...TE..A...FVGDLLDKIRGMQKLST---------------------pqkk..........................
R4G9M6_ANOCA/1-142                  .........................................MAANRVGRRLGRASPARPSa....alSP.E..AS.RTdrtpspgI..Q..RR...Q..AR.VTVKYD...RREL...QR...RLDTEKWIDGRLEELYQ.......G..Q.....E..E...E.......M.PD.......E.....V..NID.ALLEMGTDSERA....K....KL.QSIL...E..S....C...H...N...N...TE..E...FIQELLGKLRGLRTEHVLRR------------------tspggrvdv.....................
G8F528_MACFA/93-156                 .......................................pp-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDARA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
W5NM54_LEPOC/6-66                   ........................spesspqprvyfqtppg-------------------.......AE.E..AE.VP.......V..-..RK...Q..GR.VTVKYD...RKEL...RK...RLNLEEWIIDQLTELYD.......-..-.....-..-...-.......-.--.......-.....-..---.------------....-....--.----...-..-....-...-...-...-...--..-...--------------------------------------ce............................
U3JUF6_FICAL/5-129                  ....................asnssalprvtfqtpekpgee-------------------.......--.-..--.-S.......S..H..RK...L..GK.LTIKYN...RKDL...QR...WLDLEEWINAQLQELYQ.......C..RlreetE..A...A.......A.PE......pQ.....I..DLE.DLLEVPNEEQ-K....L....KL.QEIL...H..E....C...S...S...P...TE..D...FITELLSRLRGLRKVTNPQ-------------------kk............................
G1NJ36_MELGA/1-64                   .........................................-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..Q.....E..E...E.......M.PD......vE.....I..DID.DLLDAANEEERA....L....KL.QETL...V..D....C...Y...K...P...TE..E...FIKELLTRIRGMRKLSPPQKK-----------------si............................
F7GNA1_MACMU/1-45                   ........................................m-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..-.....-..-...-.......-.--.......-.....-..---.---DLST-EEQK....T....QL.EAIL...G..N....C...P...R...P...TE..A...FISELLSQLKKLRR------------------------lsrpqk........................
H9JZY1_APIME/4-126                  ......................ggvltaersparanlhvaf-------------------.......-T.E..KG.EV.......K..E..RR...E..KF.LTAKYG...SHQMsliRK...RLAVEMWLFDELEKLYE.......S..V.....N..EsgkN.......R.EV.......E.....I..DID.ELLDMDSDEHRR....R....FL.QELL...V..D....T...KkppH...D...IN..K...FINDLLEKAK----------------------------tl............................
PP14D_RAT/21-143                    ............................kkvrwssekrrra-----------SSTDSESK.......TH.L..DI.SKl.....pR..S..RR...P..SR.LTVKYD...RGHL...QR...WLEMEQWVDAQVQELFQ.......G..Q.....A..D...T.......S.EP.......E.....I..DLE.ALMELSTDEQRT....Q....-L.EAIL...Q..D....C...P...G...N...RE..P...FISELLSQLKRLRR------------------------lsr...........................
F6T9E6_CALJA/1-136                  .........................................MAAQRLGKRVLSKLQSPSR.......AR.G..PG.GSp....ggL..Q..KR...H..AR.VTVKYD...RREL...QR...RLDVEKWIDGRLEELYR.......G..M.....E..A...D.......M.PD.......E.....V..NID.ELLELESEEERR....R....KI.QGLL...K..S....C...R...S...P...IE..D...FIQELLAKLHGLHRQPGLHQ------------------pspshdgsls....................
F6YMT9_HORSE/1-90                   .........................................-------------------.......--.-..--.--.......-..-..--...-..--.----YD...RKEL...RK...RLVLEEWIVEQLGQLYG.......C..E.....E..E...E.......M.PE......vE.....I..DID.DLLDADSEEDRA....S....KL.REAL...I..D....C...Y...K...P...TE..E...FIKELLSRIRGMRKLNPPQK------------------ktv...........................
V9LKU0_CALMI/3-119                  ..........................nvlqlsrwlgvgegg-------------------.......--.-..--.ET.......P..A..RR...Q..GR.VTVKYD...RKEL...RR...RLNLEEWIIGQLTVLYD.......C..E.....E..E...A.......I.PE......lE.....I..DVD.ELLDLPSETQRG....A....RL.EALL...T..D....C...Y...K...P...TE..V...FVKELLEQIRGMQKLTT---------------------pqkyt.........................
PP14B_HUMAN/39-147                  .............................egpggaddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWILEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDARA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
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PP14A_MOUSE/1-136                   .........................................MAAQRLGKRVLSKLQSPSR.......AR.G..PG.GSp....sgL..Q..KR...H..AR.VTVKYD...RREL...QR...RLDVEKWIDGCLEELYR.......G..R.....E..S...D.......M.PD.......E.....V..NID.ELLELDSEEERC....R....KI.QGLL...E..A....C...A...N...P...TE..D...FVQELLAKLRGLHKQP----------------------gfpqpspsddpsls................
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H3D652_TETNG/22-141                 ...........................tspqprvyfqtpag-------------------.......TT.E..EP.ET.......P..V..RK...Q..GR.VTVKYD...RKEL...RK...RLNLEEWIIDQLTELYD.......C..E.....E..E...A.......I.PE......lE.....I..DVD.ELLDMPSDVERA....A....RV.KDLL...V..D....C...F...K...P...TE..D...FVSELLDKIRGMQKLST---------------------pqkk..........................
W5UEW2_ICTPU/33-141                 ..................................gpvprdd-------------------.......--.-..--.-P.......V..Q..KK...Q..GK.VTVKYD...RKEL...RK...RLVLEEWIIEQLSELYD.......C..E.....E..E...E.......M.PE......vE.....I..DID.DLLEVNSEDERA....V....KL.QESL...T..D....C...Y...K...P...TD..A...FVQELLGRIRGMRKLGAPQ-------------------kksl..........................
M7BJZ3_CHEMY/1-103                  .........................................MAANRVGRGSLARSPGSPR......aEP.A..CS.PE.......I..Q..KR...Q..AR.VTVKYD...RQEL...QR...RLDTEKWIDGRLEELYR.......G..R.....E..A...E.......M.PE.......E.....V..NID.ELLELDADGARA....A....QL.QGIP...-..-....-...-...-...-...--..-...--------------------------------------evvsqqha......................
H2NMV7_PONAB/24-145                 ......................................hwa-----SGRRRTSSTDSESK.......SH.P..DS.SK.......I..PrsRR...P..SR.LTVKYD...RGQL...QR...WLEMEQWVDAQVQELFQ.......D..Q.....A..T...P.......S.EP.......E.....I..DLE.ALMDLSTEEQKT....-....QL.EAIL...R..N....C...P...R...P...TE..T...FISELLSQLKKLRR------------------------lsrpqk........................
B3N537_DROER/4-124                  .................................gleqmndc-------ERSPNRTNLRVN.......FN.E..KG.AE.......V..K..ER...R.eKF.LTAKYG...SHQMsliRK...RLAVEMWLYDELQKLFD.......P..P.....N..E...A.......I.--.......D.....V..DID.EILDMDTDDIRR....S....HL.IRLL...S..V....C...KrpqS...D...IS..K...FIGDLLDRAK----------------------------tl............................
I0FWJ4_MACMU/1-139                  .........................................MAAQRLGKRVLSKLQSPSR.......AR.G..PG.GSp....ggL..Q..KR...H..AR.VTVKYD...RREL...QR...RLDVEKWIDGRLEELYS.......G..M.....E..A...D.......M.PD.......E.....I..NID.ELLELESEEERS....R....KI.QGLL...K..S....C...G...K...P...VE..D...FIQELLAKLQGLHRQPGLRQ------------------pspshdgslsplq.................
L5KNJ1_PTEAL/1-134                  .........................................MAAQRLGKRVLSKLQAPLR.......AR.G..PG.GSp....ggL..Q..KR...H..SR.VTVKYD...RREL...QR...RLDVEKWIDGRLEELYC.......G..R.....E..A...D.......M.PD.......E.....V..NID.ELLELDSEEDRR....R....KI.QGLL...K..S....C...M...N...P...TE..D...FIQELLVKLRGLHKQPGLRQ------------------pspsgdrs......................
B7PSA9_IXOSC/1-55                   .......................................me-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..-.....-..D...N.......H.DL.......E.....I..DLD.ELLDMESDHRRR....D....FL.RAKLvgaK..Q....S...R...D...R...VE..M...FIEELMQRAK----------------------------tl............................
G9KI58_MUSPF/1-74                   ........................................i-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...--------VEQLGQLYG.......C..E.....E..E...E.......M.PE......vE.....I..DID.DLLDADSEEERA....L....KL.REAL...V..D....C...Y...K...P...TE..E...FIQELLSRIRGMRKLS----------------------ppqkkt........................
E2RC84_CANFA/37-140                 ...........................agegpggaddegsv-------------------.......--.-..--.--.......-..-..RC...Q..GK.VTVKYD...RKLL...--...----EEWILEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDLESDDTQA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIQGMQKL-----------------------gtpqk.........................
I3K2I7_ORENI/3-122                  .........................amasdpstqsrvmfqa-------------------.......TD.K..AE.EP.......A..H..RK...L..GK.LTVKYN...RKDL...QK...RLDIEEWIDGQLHLLFD.......C..E.....E..E...E.......I.PE......lE.....I..DID.ELLELS-DEGQR....T....RL.EELL...H..E....C...G...K...P...KE..D...FINGLLYRIKGLRKM-----------------------sgplk.........................
G3N903_GASAC/1-138                  .................................rmnkscsn--------------QSPSRa....saDR.D..AA.QN.......L..Q..RR...H..IR.VTVKYN...RKEL...QR...RMEVEKWIDCELEKLYK.......G..R.....E..E...D.......M.PA.......E.....V..NID.ELLDLRTDEERT....E....RL.QDIF...H..S....C...N...K...E...SK..V...FVCELLFKLHGLQKHEDLHNNGIDLPQLHIYPTRPGS-a.............................
U6JE53_ECHGR/2-91                   ....................sgkheitpkvnfpdivedetp-------------------.......--.-..--.--.......T..H..KR...H..--.LTARYDkktRRLM...RE...KLNLEDFIYAELRKVYL.......R..D.....D..D...E.......W.DC.......E.....M..DVD.QLIRLNES----....-....--.----...-..-....-...-...-...-...--..-...--------------------------------------grkayievtfe...................
B4MU57_DROWI/4-124                  .................................gleqmndc-------ERSPNRTNLRVN.......FN.E..KG.AE.......V..K..ER...R.eKF.LTAKYG...SHQMsliRK...RLAVEMWLYDELQKLFD.......P..P.....S..E...A.......I.--.......D.....V..DID.EILDMDTDDIRR....S....HL.IRLL...S..V....C...KrpqS...D...IS..K...FISDLLDRAK----------------------------tl............................
T0MDQ8_9CETA/48-143                 .....................................vqwa-----SGRRRISSSDSESKs.....hSD.P..AK.AS.......R..S..RR...S..SR.LTVKYD...RGQL...QR...WLEMEQWVDAQVQELFQ.......D..Hp...tP..S...E.......T.SE......pE.....I..DLE.ALMELSTEEQKT....Q....--.----...-..-....-...-...-...-...--..-...--------------------------------------leve..........................
V9LJB7_CALMI/13-128                 ...............................sggsggsggs-------------------.......--.-..--.GA.......A..P..RR...Q..AR.VTVKYD...RRGL...QH...RLDVEKWIEDSVCQLYR.......E..Q.....E..D...E.......M.PE.......E.....V..NID.DLLELETDQERT....N....QL.QILF...A..S....C...D...R...N...TD..V...FIGELVTKLEGLHKAKTMQRVGQEV-------------rq............................
K7EMN0_HUMAN/1-95                   .........................................MAAQRLGKRVLSKLQSPSR.......AR.G..PG.GSp....ggL..Q..KR...H..AR.VTVKYD...RREL...QR...RLDVEKWIDGRLEELYR.......G..M.....E..A...D.......M.PD.......E.....I..NID.ELLELESEEERS....R....KI.Q---...-..-....-...-...-...-...--..-...--------------------------------------p.............................
PP14D_MOUSE/22-143                  ..............................kvhwasekrrr----------ASSTDSESK.......TH.LdiSK.LP.......R..S..RR...P..SR.LTVKYD...RGHL...QR...WLEMEQWVDAQVQELFQ.......G..Q.....E..E...S.......S.EP.......E.....I..DLE.ALMDLSTEDQRT....Q....-L.EAIL...Q..D....C...P...G...N...RE..P...FISELLSQLKRLRR------------------------lsr...........................
G3TFA0_LOXAF/37-166                 ..................srsagssredsalvapaaaggql-------------------.......--.-..QQ.QQ.......Q..Q..RRh.qQ..GK.VTVKYD...RKEL...RK...RLVLEEWIVEQLGQLYG.......C..E.....E..E...E.......M.PE......vE.....I..DID.DLLDADSEEERA....V....KL.QEAL...V..D....C...Y...K...P...TE..E...FIKELLSRIRGMRKLSP---------------------pqkktv........................
D2GW97_AILME/23-145                 .....................................vrwt-----SGRRRTSSTDSESK......sHP.D..PS.KV......aR..S..RR...P..SR.LTVKYD...RGQL...QR...WLEMEQWVDGQVQELFR.......D..Q.....P..T...P.......S.EP.......E.....I..DLE.ALMELSTEEQ-K....T....HL.EAIL...R..N....C...P...R...P...TE..P...FISELLSQLKKLRR------------------------lsrpqk........................
W5NY86_SHEEP/1-64                   .........................................-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..Q.....E..E...E.......M.PD......vE.....I..DID.DLLDADSEEERA....L....KL.REAL...V..D....C...Y...K...P...TE..E...FIKELLSRIRGMRKLSPPQ-------------------kkav..........................
PP14C_MOUSE/36-164                  .......................sssssgssredsapvttv------------------A.......AA.G..QV.QQ.......Q..Q..RR...HqqGK.VTVKYD...RKEL...RK...RLVLEEWIVEQLGQLYG.......C..E.....E..E...E.......M.PD......vE.....I..DID.DLLDANSEEERA....S....KL.QEAL...V..D....C...Y...K...P...TE..E...FIRELLSRIRGMRKLSP---------------------pqkksv........................
Q0IHD5_XENLA/12-129                 ............................hptsprvyfqspg-------------------.......--.E..TA.EQ.......T..D..RR..hQ..GK.VTVKYD...RKEL...RK...RLRLEEWILEQLVELYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMETDAQRG....E....RV.KKLL...V..D....C...Y...K...P...TE..A...FISGLLEKIQGMQKLST---------------------pqkk..........................
T1P9U5_MUSDO/4-124                  .................................sleqmndt-------ERSPNRTNLRVN.......FN.E..KG.SE.......V..K..ER...R.eKF.LTAKYG...SHQMsliRK...RLAVEMWLYDELQKLFD.......P..P.....T..E...A.......I.--.......D.....V..DID.EILDMDTDDIRR....S....HL.IRLL...S..V....C...KrpqS...D...IS..K...FISDLLDRAK----------------------------tl............................
A0A034VTY0_BACDO/5-124              ..................................leqmndc-------ERSPNRTNLRVN.......FN.E..KG.AE.......V..K..ER...R.eKF.LTAKYG...SHQMsliRK...RLAVEMWLYDELQKLFD.......P..P.....S..E...A.......I.--.......D.....V..DID.EILDMDTDDIRR....S....HL.IRLL...S..V....C...KrpqA...D...IS..K...FISDLLDRAK----------------------------tl............................
L8HVD0_9CETA/5-65                   .....................................skql-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......S..K.....E..A...D.......M.PD.......E.....V..NID.ELLELESEEERS....R....KI.QD--...-..-....-...-...-...-...--..-...FVQELLAKLRGLHKQPGLRQ------------------pspsgdg.......................
F6RDK6_MACMU/39-108                 ............................gegpggtddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTVQYD...LKEL...RK...RLNLEEWIQEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDKESD----....-....--.----...-..-....-...-...-...-...--..-...--------------------------------------d.............................
M4A2I6_XIPMA/10-128                 ............................spqprvyfqtpag-------------------.......TT.E..EP.ET.......P..V..RK...Q..GR.VTVKYD...RKEL...RK...RLNLEEWIIDQLTDLYD.......C..E.....E..E...A.......I.PE......lE.....I..DVD.ELLDMPSDVERA....A....RV.KDLL...V..D....C...F...K...P...TE..D...FISELLDKIRGMQKLST---------------------pqkk..........................
G5AMC3_HETGA/15-94                  .....................................vlrr-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...----------TLELIHS.......Q..Q.....E..A...D.......M.PD.......E.....V..NID.ELLELESEEDRR....R....KI.QGLL...R..S....C...T...D...P...TE..D...FIQELLAKLRGLHKQPGLRQ------------------pspsedds......................
W5LF96_ASTMX/8-127                  ...........................esspqprvyfqtpp------------------A.......TE.E..TE.-T.......P..V..RK...Q..GR.VTVKYD...RKEL...RK...RLNLEEWIIDQLTELYD.......C..E.....E..E...A.......I.PE......lE.....I..DVD.ELLDMQDDVDRA....A....RV.KELL...V..D....C...Y...N...P...TE..D...FVSELLDKIRGMQKLST---------------------pqkk..........................
V9LEN8_CALMI/3-120                  ...............................epstqsrvyf----------------QAA.......SK.E..EE.QP.......T..H..RK...M..GK.FTVKYD...RKDL...QK...RLEVEEWMDVQIRQLLG.......C..K.....E..E...E.......T.PV......lE.....I..DVD.ELLELPDEKQRS....-....KL.QAIL...Q..G....C...C...K...P...TD..D...FINELLIRIKGLRKMTTPQ-------------------kk............................
S4RYZ1_PETMA/14-151                 saqgngkqqqqqpghgeqqqqqqqqgpvhpgggaappmphg-------------------.......--.-..--.--.......-..R..RA...G..SK.VTVKYN...RKEL...QK...RLDLEEWIDERLHLLYD.......C..D.....E..E...E.......M.PE......lE.....I..DID.QLLDMNTDEERA....E....QL.REIL...Q..E....C...C...S...S...SE..E...FVLELLSRIKGMKKLS----------------------tnkk..........................
G3RYU7_GORGO/44-149                 ...............................pggaddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWILEQLTRLYD.......C..Q.....A..W...V.......L.PS.......D.....P..SAF.TSSSLPGSCDRC....L....GE.GKGV...C..L....P...S...H...P...TQ..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
U5EQV0_9DIPT/5-123                  .....................vetmnecerspgrtglrvnf-------------------.......-T.E..KG.EV.......K..E..RR...E..KF.LTAKYG...SHQMsliRK...RLAVEMWLYDELQKLFD.......P..P.....T..E...A.......I.--.......D.....V..DID.EILDMDTDDIRR....S....HL.FSLL...S..E....C...KrppQ...D...IS..K...FISDLLDRAK----------------------------tl............................
A8Y4I0_CAEBR/5-112                  ..................................ekharfg-------------------.......--.D..SK.SR.......M..E..DR...S..RV.LTMKYG...KQQMaliRK...RMKVENWIETEVTELFN.......G..N.....E..N...N.......T.VD.......-.....I..DLD.VIQDIEDVTGKR....K....YA.FEQL...Q..KahcpC...S..mD...K...II..M...FLDELITQLNT---------------------------l.............................
M3YP53_MUSPF/37-145                 .............................egpggaddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWILEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDTRA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
S9WX33_9CETA/6-67                   ..................................kqnvftf-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...----------------A.......P..Q.....E..E...E.......M.PD......vE.....I..DID.DLLDADSEEERA....L....KL.QE--...-..-....-...-...-...-...--..-...FIKELLSRIRGMRK------------------------lsppqkktv.....................
G1QYA5_NOMLE/39-147                 .............................egpggaddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWILEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDARA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
F6Y7A1_CANFA/52-174                 ................................apaaaagqv--------------QQQQQ.......QQ.Q..QQ.QQ.......Q..Q..RRh.qQ..GK.VTVKYD...RKEL...RK...RLVLEEWIVEQLGQLYG.......C..E.....E..E...E.......M.PE......vE.....I..DID.DLLDADSEEERA....L....KL.REAL...V..D....C...Y...K...P...TE..E...FIQELLSRIRGMRKLNP---------------------pqkkt.........................
V9LJY3_CALMI/1-135                  .........................................MAAYRMGKKGSGGFSALGK.......GG.G..SG.GSgg..sgaA..P..RR...Q..AR.VTVKYD...RRGL...QH...RLDVEKWIEDSVCQLYR.......E..Q.....E..D...E.......M.PE.......E.....V..NID.DLLELETDQERT....N....QL.QILF...A..S....C...N...R...T...TD..V...FIGELVTKLEGLHKAKTMQRVGQEV-------------rq............................
M7CFF9_CHEMY/3-104                  ......................sksrdlprvtfeapekpge-------------------.......--.-..--.ES.......S..H..KK...L..GK.LTVKYN...RKDL...QR...WLDLEEWIDAQLQELYQ.......Y..Ql..qeE..E...Dt.....aT.PE......pE.....I..DIE.DLLEVSNEEQKS....-....KL.Q---...-..-....-...-...-...-...--..-...--------------------------------------lmdsflltrrt...................
H2RF42_PANTR/39-147                 .............................egpggaddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWILEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDARA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
Q4RRA1_TETNG/169-235                .....................................rpdw-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..-.....E..E...E.......M.PE......vE.....I..DID.DLLEVTSDDERA....S....KL.QESL...T..D....C...Y...K...P...TE..D...FVRELLCRIRGMRKLSAPTKKG----------------l.............................
C3Y0Q5_BRAFL/4-62                   ...........................rvsfgspsdsvapk-------------------.......-P.V..QP.QQ.......A..P..RR...N..VK.ATVKYN...RALL...KR...RLELEEWVDEALRDIYE.......-..-.....-..-...-.......-.--.......-.....-..---.------------....-....--.----...-..-....-...-...-...-...--..-...--------------------------------------cda...........................
G3R934_GORGO/41-87                  ...............................pggaddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWILEQLTRLYD.......C..-.....-..-...-.......-.--.......-.....-..---.------------....-....--.----...-..-....-...-...-...-...--..-...--------------------------------------qa............................
G3QTH2_GORGO/1-139                  .........................................MAAQRLGKRVLSKLQSPSR.......AR.G..PG.GSp....ggL..Q..KR...H..AR.VTVKYD...RREL...QR...RLDVEKWIDGRLEELYR.......G..M.....E..A...D.......M.PD.......E.....I..NID.ELLELESEEERS....R....KI.QGLL...K..S....C...G...K...P...VE..D...FIQELLAKLQGLHRQPGLRQ------------------pspshdgslsplq.................
I3KFM0_ORENI/2-136                  ...............................aakwtnaale----------------ENA.......DE.E..RS.RS.......I..P..KR...H..AR.VTVKYN...RKEL...QR...RLDVEKWIDESLDRLYA.......G..Q.....E..G...D.......M.PE.......E.....V..NID.DLLDLPNEEERV....K....KL.QELL...Q..K....C...R...S...S...TE..A...FIKELVVKLQGVHRKDELQSEGIEHPVICHGHYRHEPY..............................
G7PAX8_MACFA/1-45                   ........................................m-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..-.....-..-...-.......-.--.......-.....-..---.---DLST-EEQK....T....QL.EAIL...G..N....C...P...R...P...TE..A...FISELLSQLKKLRR------------------------lsrpqk........................
E3MQD0_CAERE/5-112                  ..................................ekharfg-------------------.......--.D..SK.SR.......M..E..DR...S..RV.LTMKYG...KQQMaliRK...RMKVENWIETEVTKLFN.......G..N.....E..N...N.......N.V-.......D.....I..DLD.VIQDMEDVTGKR....K....YA.FEQL...Q..KahcpC...S..mD...K...II..M...FLDELIIQLNT---------------------------l.............................
H9YV07_MACMU/39-147                 .............................egpggaddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWILEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDARA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
F1LVP5_RAT/5-82                     .................................llslella-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...----------ELTRLYY.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDTRA....A....RV.KELL...V..N....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
G1PXW0_MYOLU/38-166                 ......................sgagssredsapvapaagq-------------------.......QQ.Q..QQ.QQ.......Q..Q..RRh.qQ..GK.VTVKYD...RKEL...RK...RLVLEEWIVEQLGRLYG.......C..E.....E..E...E.......M.PD......vE.....I..DID.DLLDADSEEERA....L....KL.REAL...V..D....C...H...K...P...TE..E...FIKELLSRIRGMRKLSP---------------------pqkktv........................
U6D543_NEOVI/1-94                   ........................................g-------------------.......--.-..--.--.......-..-..--...-..-K.VTVKYD...RKEL...RK...RLNLEEWILEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDTRA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
W8C4G5_CERCA/4-124                  .................................gleqmndc-------ERSPNRTNLRVN.......FN.E..KG.AE.......V..K..ER...R.eKF.LTAKYG...SHQMsliRK...RLAVEMWLYDELQKLFD.......P..P.....S..E...A.......I.--.......D.....V..DID.EILDMDTDDIRR....S....HL.IRLL...S..V....C...KrpqA...D...IS..K...FISDLLDRAK----------------------------tl............................
G3I882_CRIGR/48-121                 .............................lrrmsdefegsf-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..K.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDTRA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
G1LVE6_AILME/1-134                  .......................................vt--KKRIGKEVRSKLQSPSR.......AR.G..PG.GSp....ggL..Q..KR...H..AR.VTVKYD...RREL...QR...RLDVEKWIDGRLEELYR.......G..R.....E..A...D.......M.PD.......E.....V..NID.ELLELESEEDRS....R....KI.QGLL...K..S....C...R...N...P...TE..D...FVQELLGKLRGLHKQPGLR-------------------ppspsgnhs.....................
M7B7W8_CHEMY/45-104                 ......................................srd-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..E.....E..A...E.......M.PD.......E.....V..NID.ELLELDADEARA....A....QL.Q---...-..-....-...-...-...-...--..A...FVQELLLKLRGLQKQQALRR------------------pspelqkr......................
B4P0U2_DROYA/4-124                  .................................gleqmndc-------ERSPNRTNLRVN.......FN.E..KG.AE.......V..K..ER...R.eKF.LTAKYG...SHQMsliRK...RLAVEMWLYDELQKLFD.......P..P.....N..E...A.......I.--.......D.....V..DID.EILDMDTDDIRR....S....HL.IRLL...S..V....C...KrpqS...D...IS..K...FIGDLLDRAK----------------------------tl............................
H0WGL9_OTOGA/23-145                 .....................................iqwa-----SGRRRTSSTDSESK.......SH.P..DL.SK.......V..PrsRR...P..SR.LTVKYD...MGQL...QR...WMEMEQWVNAQLQELFQ.......D..Q.....P..D...L.......S.EP.......E.....I..DLE.ALMELSTDEQKI....Q....-L.EAIL...Q..N....C...S...Q...S...TE..P...FISELLSQLKKLRR------------------------lsrpqk........................
F7CDX3_MACMU/34-147                 .........................pgaagegpsgaddegp-------------------.......--.-..--.--.......-..V..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWILEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDARA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLS----------------------tpkkk.........................
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PP14B_PIG/39-147                    .............................egpggaddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWILEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDTRA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
PP14A_RAT/1-132                     .........................................MAAQRLGKRVLSKLQSPSR.......AR.G..PG.GSp....sgL..Q..KR...H..AR.VTVKYD...RREL...QR...RLDVEKWIDGRLEELYR.......G..R.....E..A...D.......M.PD.......E.....V..NID.ELLELDSEEERC....R....KI.RGLL...E..A....C...L...N...P...TE..D...FVQELLAKLRGLHKQP----------------------gfpqpspsdd....................
PP14A_PIG/1-132                     .........................................MAAQRLGKRVLSKLQSPSR.......AR.G..PG.GSp....ggL..Q..KR...H..AR.VTVKYD...RREL...QR...RLDVEKWIDGRLEELYR.......G..R.....E..A...D.......M.PD.......E.....V..NID.ELLELESEEERS....R....KI.QGLL...K..S....C...T...N...P...TE..N...FVQELLVKLRGLHKQPGLRQ------------------pspsgd........................
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T1GH88_MEGSC/5-97                   .................................leslndce--------RSPNRTNLRVN.......FN.D..KG.SE.......V..K..ER...R.eKF.LTAKYG...SHQMsliRK...RLAVEMWLYDELQKLFD.......P..P.....S..E...A.......I.--.......D.....V..DID.EILDMDTDDIRR....S....H-.----...-..-....-...-...-...-...--..-...--------------------------------------li............................
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Q641E2_XENLA/1-138                  .........................................MAANKVGKRLTNKPHSPSK.......SR.D..SN.QG.......I..Q..RR...Q..AR.ITVKYD...RKEL...QK...RLDVEKWIDEQMEELYL.......G..R.....E..V...D.......M.PD.......E.....V..NID.DLLDLETDEDRR....R....SL.QVIL...K..S....C...T...N...N...TE..V...FIRELLLRLKGLQKQTLLKKNGLEVSSEEHIVEH----a.............................
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G5B6Q6_HETGA/17-136                 ...................gprqsppgaagegsgdaddegp-------------------.......--.-..--.--.......-..V..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWILEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDTRA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
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Q567W8_DANRE/2-137                  ..................................aeethtg--------------HSPELd.....cAR.E..HG.MN.......L..H..KR...H..SR.VTVKYN...RKQL...QK...RLDVEKWIDEALDKLYE.......G..K.....V..E...D.......M.PE.......E.....V..NID.DLLDLPSDEART....H....RL.QALL...Q..S....C...S...S...N...TE..A...FIAELLQKLHGLHKQEELQNEGIEHPCHHTYPHHHGN-m.............................
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S7P1M8_MYOBR/23-115                 .....................................vqwa-----SGKRRTSSTDSESK......sHP.D..PSkAS.......R..S..RR...P..SR.LTVKYD...RGHL...QR...WLDMEQWVDAKVQELFQ.......D..Q.....P..T...P.......S.EL.......E.....I..DLE.ALMELSTEEQKT....Q....--.----...-..-....-...-...-...-...--..-...--------------------------------------leve..........................
F6XFX8_MACMU/1-93                   ........................................x-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...RLDVEKWIDGRLEELYS.......G..M.....E..A...D.......M.PD.......E.....I..NID.ELLELESEEERS....R....KI.QGLL...K..S....C...G...K...P...VE..D...FIQELLAKLQGLHRQPGLRQ------------------pspshdgslsplqd................
H3BAE7_LATCH/1-134                  .........................................MAANKVGKRAQNKFLSPSR.......NR.E..AG.LA.......V..Q..KR...Q..AR.VTVKYD...RKEL...QK...RLDVEKWIDERLEELYL.......G..R.....E..K...E.......M.PE.......E.....L..NID.DLLDLASDEERS....R....KL.KDML...H..S....C...N...S...N...IE..E...FTTELLIKLHGLPKQNVLQRNGIEHQEVE---------kp............................
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H9G8B8_ANOCA/1-143                  .........................................MAANRVGRRLGRASPARPSa....alSP.E..AS.RTdrtpspgI..Q..RR...Q..AR.VTVKYD...RREL...QR...RLDTEKWIDGRLEELYQ.......G..Q.....E..E...E.......M.PD.......E.....V..NID.ALLEMGTDSERA....K....KL.QSIL...E..S....C...H...N...N...TE..E...FIQELLGKLRGLRTEHVLRR------------------tspggrvdve....................
D2HEQ3_AILME/1-48                   ....................................qqkqq-------------------.......--.-..--.QQ.......R..R..HQ...Q..GK.VTVKYD...RKEL...RK...RLVLEEWIVEQLGQLYG.......-..-.....-..-...-.......-.--.......-.....-..---.------------....-....--.----...-..-....-...-...-...-...--..-...--------------------------------------cevpe.........................
I3N0F0_SPETR/1-120                  .........................................---------------SPSR.......AR.G..PG.GSp....ggL..Q..KR...H..AR.VTVKYD...RREL...QR...RLDVEKWIDGRLEEMYR.......G..R.....E..A...D.......M.PD.......E.....V..NID.ELLELESEEERS....R....KI.QGPQ...S..Q....H...P...P...C...PQ..D...FVQELLAKLRGLHKQPGLRQ------------------pspsaegsl.....................
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M0R6N9_RAT/1-74                     .........................................-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..-.....E..S...D.......M.PN.......E.....V..NIDdELLELDSQEERR....C....KI.QGLL...E..Y....Y...T...N...P...TE..G...IIQELLAKLHGMHKQPQ---------------------psqsddyspspcqdwth.............
F5H2U0_HUMAN/9-72                   .......................................pp-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDARA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
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E1GFU5_LOALO/1-72                   .......................................ml-------------------.......--.-..--.--.......-..-..--...-..--.-TMKYG...KHQMmliKK...RMNVENWIDDQLNELYK.......A..A.....T..D...S.......I.--.......D.....I..DVD.AVLDLNTESERR....R....YV.----...-..-....-...-...-...-...--..-...--------------------------------------mvnnacqiyynkc.................
S7MT33_MYOBR/1-45                   .........................................-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..-.....-..-...-.......-.--.......-.....-..---.----MESDDTRA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLSTP--------------------qkk...........................
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H2Q971_PANTR/24-89                  ......................................hwa-----SGRRRTSSTDSESK.......SH.P..DS.SK.......I..PrsRR...P..SR.LTVKYD...RGQL...QR...WLEMEQWVDAQVQELFQ.......-..-.....-..-...-.......-.--.......-.....-..---.------------....-....--.----...-..-....-...-...-...-...--..-...--------------------------------------slal..........................
F7H6G4_CALJA/24-143                 .......................ffqsprgcaegstgsvqq-------------------.......--.-..-Q.QR.......R..R..HQ...Q..GK.VTVKYD...RKEL...RK...QLVLEEWILEQLGQLYG.......C..E.....E..E...E.......V.PE......vE.....T..DID.DLLDADSDEERA....S....KL.QEAL...V..D....C...S...K...P...TE..E...FIKELLSRIRGMRKL-----------------------sppqkk........................
PP14C_RAT/35-164                    .........................essshsgssredsapv---------------ATVA.......AA.G..QV.QQ.......Q..Q..RR...HqqGK.VTVKYD...RKEL...RK...RLVLEEWIVEQLGQLYG.......C..E.....E..E...E.......M.PD......vE.....I..DID.DLLDADSEEERA....S....KL.QEAL...V..D....C...Y...K...P...TE..E...FIRELLSRIRGMRKLSP---------------------pqkksv........................
E1BE60_BOVIN/1-132                  .........................................MAAQRLGKRVLSKLQAPSR.......AR.G..PG.GSp....ggL..Q..KR...H..AR.VTVKYD...RREL...QR...RLDVEKWIDGRLEELYR.......G..R.....E..A...D.......M.PD.......E.....V..NID.ELLELESEEERS....R....KI.QGLL...K..S....C...T...N...P...TE..D...FVQELLAKLRGLHKQPGLRQ------------------pspsgd........................
H2ZX56_LATCH/25-83                  .......................ffqaapaapasgtgpaar-------------------.......--.-..-D.DS.......A..Q..RR...Q..GK.VTVKYD...RKEL...RK...RLILEEWIVEQLSELYD.......-..-.....-..-...-.......-.--.......-.....-..---.------------....-....--.----...-..-....-...-...-...-...--..-...--------------------------------------ce............................
H3D0T8_TETNG/2-129                  ............................seqqhagpghvhd-------------------.......SR.R..SP.GR.......N..Q..RR...Q..AR.VTVQYN...RKEL...QR...RLDVEKWVECGLDELYR.......G..R.....E..D...E.......M.PE.......E.....V..NID.ELLDLKTDEERR....Q....RL.QVIF...R..S....S...H...S...S...TE..V...FIRDLVQKLQGLQKQEELHNNGIQLPQLHV--------y.............................
G1Q9T3_MYOLU/2-72                   ....................................pqlrp-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...--------------LSP.......P..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDTRA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
H0ZKH1_TAEGU/1-95                   ......................................rkl-------------------.......--.-..--.--.......-..-..--...-..GK.LTIKYN...RKDL...QR...WLDLEEWINTQLQELYQ.......C..R.....A..A...A.......P.EP.......Q.....I..DLE.DLLEVPNEEQKL....K....LQ.IGLL...N..I....C...Q...N...W...VN..D...FITELLSRLRGLRRVT----------------------npqk..........................
K7ISN1_NASVI/3-127                  .....................agggvltaersparsnlhva-------------------.......FT.E..EG.KV.......K..E..RR...E..KF.LTAKYG...SHQMsliRK...RLAVEMWLFEELSKLYE.......S..K.....N..E...S.......G.NSr....evE.....V..DID.ELLDMDSDEHRK....S....YL.QGLL...V..D....A...KkppH...D...VK..K...FINDLLEKAK----------------------------tl............................
G3N0C3_BOVIN/1-62                   .........................................-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDTRA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
H2L402_ORYLA/1-143                  .....................................sere----RTAEMAAEETRAPASe.....lAP.E..HG.GH.......I..P..KR...H..AR.VTVKYN...RREL...QR...RLDVEKWIDESLDRLYR.......G..Q.....E..E...E.......M.PE.......E.....V..NID.ELLDLPSDRERA....Q....RL.QDLL...Q..K....C...R...N...S...TE..V...FIKELLVKLHGVHKQNELQSEGIEHPVICHSHPRHEPY..............................
U3IQY6_ANAPL/1-64                   .........................................-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...-----------------.......-..Q.....E..E...E.......M.PD......vE.....I..DID.DLLDAANEEERA....L....KL.QETL...V..D....C...Y...K...P...TE..E...FIKELLTRIRGMRKLSPPQKK-----------------si............................
B4LS81_DROVI/4-124                  .................................gleqmndc-------ERSPNRTNLRVN.......FN.E..KG.AE.......V..K..ER...R.eKF.LTAKYG...SHQMsliRK...RLAVEMWLYDELQKLFD.......P..P.....S..E...A.......I.--.......D.....V..DID.EILDMDTDDIRR....S....HL.IRLL...S..V....C...KrpqS...D...IS..K...FIGDLLDRAK----------------------------tl............................
E0VZG3_PEDHC/20-112                 .................dsirsegspakaglhvnfiektdv-------------------.......--.-..--.--.......K..E..KR...E..KF.LTAKYG...SHQMgliRK...RLAVEMWLYDELQKLFE.......S..P.....V..V...K.......-.-V.......E.....V..DID.ELLDMDSDDQRR....K....HL.EV--...-..-....-...-...-...-...--..-...--------------------------------------fi............................
H2URV0_TAKRU/20-138                 ............................spqprvyfqtpag-------------------.......TT.E..EP.ET.......P..V..RK...Q..GR.VTVKYD...RKEL...RK...RLNLEEWIIDQLTDLYD.......C..E.....E..E...A.......I.PE......lE.....I..DVD.ELLDMPSDVERA....A....RV.KDLL...V..D....C...F...K...P...TE..D...FVSELLDKIRGMQKLST---------------------pqkk..........................
G0P6N1_CAEBE/5-112                  ..................................ekharfg-------------------.......--.D..SK.SR.......M..E..DR...S..RV.LTMKYG...KQQMaliRK...RMKVENWIETEVTKLFN.......G..N.....E..N...N.......N.V-.......D.....I..DLD.VIQDMEDVTGKR....K....YA.FEQL...Q..KahcpC...S..mD...K...II..M...FLDELIIQLNT---------------------------l.............................
W4YYP8_STRPU/11-79                  ....................nrvsfagseeqqipgvdhrrg-------------------.......SI.N..SE.EK.......A..K..RK...H..QN.VTCKYD...RKVM...RI...RLDIEEWMDEQLRELYE.......C..-.....-..-...-.......-.--.......-.....-..---.------------....-....--.----...-..-....-...-...-...-...--..-...--------------------------------------easi..........................
U4TYT5_DENPD/71-199                 .....................................vgdv---QRTTNRSPAKSGLHVN.......FK.E..KG.EV.......K..E..KR...E..KF.LTAKYG...HHQMsliRK...RLAVEMWLYEELKKLYE.......S..T.....N..N...K.......I.EDsvsneevE.....I..DID.ELLDMDSDEHRR....R....HL.QNLL...V..Na.kgS...Q...N...D...VK..S...FINDLLEKAK----------------------------tl............................
H0Y1H3_OTOGA/26-134                 .............................egpggtddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWILEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDTRA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
H2NYN1_PONAB/1-128                  .........................................MAAQRLGKRVLSKLQSPSR.......AR.G..PG.GSp....ggL..Q..KR...H..AR.VTVKYD...RREL...QR...RLDVEKWIDGRLEELYR.......G..M.....E..A...D.......M.PD.......E.....I..NID.ELLELESEEERS....R....KI.QD--...-..-....-...-...-...-...--..-...FIQELLAKLQGLHRQPGLRQ------------------pspshdgslsplq.................
K7GHF4_PELSI/1-75                   .......................................ml-------------------.......--.-..--.--.......-..-..--...-..--.------...----...--...---------EQLGQLYG.......C..E.....E..E...E.......M.PD......vE.....I..DID.DLLDAANEEERA....I....KL.QEAL...V..D....C...Y...K...P...TE..E...FIRELLTRIRGMRKLSPPQKK-----------------si............................
M3X951_FELCA/1-92                   .........................................-------------------.......--.-..--.--.......-..-..--...-..--.------...RREL...QR...RLDVEKWIDGRLEELYR.......G..R.....E..A...D.......M.PD.......E.....V..NID.ELLELESEEERS....R....KI.QGLL...K..S....C...K...N...P...TE..D...FVQELLVKLRGLHKQPGLRQ------------------pspsgdss......................
M3WW18_FELCA/41-149                 .............................egpggaddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTVKYD...RKEL...RK...RLNLEEWILEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDMESDDTRA....A....RV.KELL...V..D....C...Y...K...P...TE..A...FISGLLDKIRGMQKLST---------------------pqkk..........................
Q7PN37_ANOGA/4-123                  ....................gvetmndcerspgrtglrvnf-------------------.......-T.E..KG.EV.......K..E..RR...E..KF.LTAKYG...SHQMsliRK...RLAVEMWLYDELQKLFD.......P..P.....T..E...A.......I.--.......D.....V..DID.EILDMDTDDIRR....S....HL.FSLL...S..A....C...KrppQ...D...IS..K...FISDLLDRAK----------------------------tl............................
A0A016UY89_9BILA/2-101              ....................................gtcqe-------------------.......--.-..--.--.......-..E..ER...N..RV.LTMKYG...KQQMmliRK...RMKIENWIDAEVAKLFN.......G..N.....D..N...N.......G.V-.......D.....I..DVD.VLLDLDSVPAKR....K....FV.FDNL...Q..Rs..hC...P...A...SmdkIT..M...FLDEMIDQLN----------------------------tl............................
G7NAF6_MACMU/22-92                  ...........................agegpggaddegpv-------------------.......--.-..--.--.......-..-..RR...Q..GK.VTVQYD...LKEL...RK...RLNLEEWIQEQLTRLYD.......C..Q.....E..E...E.......I.PE......lE.....I..DVD.ELLDKESD----....-....--.----...-..-....-...-...-...-...--..-...--------------------------------------d.............................
A0A044RKI7_ONCVO/1-114              ..............................madniakhahf-------------------.......SD.Q..KN.RK.......T..N..ER...S..RM.LTMKYG...KHQMmliRK...RMNVENWIDNQLNELYQ.......A..T.....T..T...D.......N.I-.......D.....I..DLD.AVLDLNTESERR....H....YV.TDLL...R..Kt..hCpatE...S...Q...IH..D...FLDQLMQKLN----------------------------ml............................
Q6PBJ4_DANRE/1-143                  .........................................MAANRVGRRYNNKIHSPNRg.....aSR.E..AG.LS.......V..Q..KR...Q..AR.VTVKYN...RKEL...QR...RLDVEKWIDCGLDELYL.......G..R.....E..D...E.......M.PE.......E.....V..NID.ELLDLQSDEERT....Q....KL.KDIL...H..A....C...S...N...N...TE..V...FITELVKKLHGLQKQEDLHNNGIEHPQLHIFPERQGS-s.............................
U1MDV9_ASCSU/1-112                  .............................mseemkqtrfse-------------------.......-E.N..KS.RS.......T..A..ER...G..RV.LTMKYG...KHQMmliRK...RMAVENWLDDRLVQLCD.......G..T.....V..E...-.......-.-L.......D.....I..DLD.KVLDLNTTTERR....R....YI.LDII...ErtK....C...IaspN...T...ID..D...FLDELMQKLDT---------------------------l.............................
W5NBX3_LEPOC/1-77                   .........................................MAANRVGRRYNHKVHSPNR......gPR.E..PG.LH.......L..Q..KR...Q..AR.VTVKYN...RKEL...QK...RLDVEKWIDDRLAELYL.......G..R.....E..R...A.......-.--.......-.....-..---.------------....-....--.----...-..-....-...-...-...-...--..-...--------------------------------------vtrhssngi.....................
F1SST3_PIG/23-145                   .....................................vqwa-----SGRRRTSSTDSESKs.....hSD.P..SK.VS.......R..S..RR...P..TR.LTVKYD...LGQL...QR...WLEMEQWVDTQVQELFQ.......-..Q.....D..Q...P.......T.PE......lE.....I..DLE.ALMELSTEEQKT....-....QL.EAVL...Q..N....C...P...R...P...TE..T...FISELLGQLKKLRR------------------------lsrpqk........................
H9FC93_MACMU/1-113                  .................................aaaagqvq-------------------.......--.-..--.QQ.......Q..Q..RRh.qQ..GK.VTVKYD...RKEL...RK...RLVLEEWIVEQLGQLYG.......C..E.....E..E...E.......M.PE......vE.....I..DID.DLLDADSDEERA....S....KL.QEAL...V..D....C...Y...K...P...TE..E...FIKELLSRIRGMRKLSP---------------------pqkktv........................
F1RE36_DANRE/12-154                 .........................................MAANRVGRRYNNKIHSPNRg.....aSR.E..AG.LS.......V..Q..KR...Q..AR.VTVKYN...RKEL...QR...RLDVEKWIDCGLDELYL.......G..R.....E..D...E.......M.PE.......E.....V..NID.ELLDLQSDEERT....Q....KL.KDIL...H..A....C...S...N...N...TE..V...FITELVKKLHGLQKQEDLHNNGIEHPQLHIFPERQGS-s.............................
S4NYB9_9NEOP/11-142                 ....................aaahaarspterspakaglhv------------------N.......FS.D..KG.EV.......K..E..RR...E..KF.LTAKYG...SHQMaliRK...RLAVEMWLYDELQKLYEtpgaaggG..A....gG..A...G.......G.EV.......E.....V..DID.ELLDMDSDELRR....R....HL.VTLL...A..D....AkkpQ...K...D...VH..K...FINDLLEKAK----------------------------tl............................
#=GC SS_cons                        .........................................XXXXXXXXXXXXXXXXXXX.......XX.-..-S.SSS....SSS..-..S-...S..SS.SSSSS-...SSSS...CH...HHHHHHHHHHHHHHCSS.......S..S.....S..T...T.......S.-S.......S.....S..HHH.HHHCTSSTTHHH....H....HH.HHHH...T..T....C...S...S...T...TH..H...HHHHHHHHCTTT--XXXXXX------------------XXXXXX........................
#=GC seq_cons                       ...........................................................................................+R...p..u+.lTVKYs...R+pL...p+...RLslEpWI.ppLpcLYp.......s..p.....E..-...-.......h.P-.......E.....I..DlD.-LLDhpo--pRs....t....+l.pplL...h..s....C...h...p...P...TE..t...FIp-LLs+l+Ghp+........................st............................
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