GenomeNet

Database: Pfam
Entry: PPV_E1_C
LinkDB: PPV_E1_C
Original site: PPV_E1_C 
#=GF ID   PPV_E1_C
#=GF AC   PF00519.15
#=GF DE   Papillomavirus helicase
#=GF PI   E1; 
#=GF AU   Finn RD
#=GF SE   Pfam-B_48 (release 1.0)
#=GF GA   19.70 19.70;
#=GF TC   19.90 19.80;
#=GF NC   19.60 19.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR001177;
#=GF DR   SCOP; 1f08; fa;
#=GF CC   This protein is a DNA helicase that is required for initiation
#=GF CC   of viral DNA replication.  This protein forms a complex with the
#=GF CC   E2 protein Pfam:PF00508.
#=GF SQ   60
#=GS Q8QQC0_ECPVO/176-606      AC Q8QQC0.1
#=GS VE1_MNPVA/162-593         AC Q84356.1
#=GS B4XYE1_9PAPI/200-630      AC B4XYE1.1
#=GS V9P8E0_9PAPI/174-603      AC V9P8E0.1
#=GS E2E2D0_FCDNV/348-518      AC E2E2D0.1
#=GS Q30BJ1_9PAPI/164-591      AC Q30BJ1.1
#=GS D6YRN6_WADCW/13-73        AC D6YRN6.1
#=GS E7C0H2_9PAPI/176-608      AC E7C0H2.1
#=GS VE1_HPV11/211-640         AC P04014.1
#=GS VE1_HPV04/163-590         AC Q07846.1
#=GS Q0QLX4_9PAPI/188-619      AC Q0QLX4.1
#=GS Q8JNA6_FCPVN/248-679      AC Q8JNA6.1
#=GS VE1_HPV41/178-605         AC P27551.1
#=GS VE1_HPV16/210-640         AC P03114.2
#=GS C5L5M0_PERM5/18-129       AC C5L5M0.1
#=GS A0A075B0T7_9FUNG/28-237   AC A0A075B0T7.1
#=GS B8R1U9_9PAPI/162-593      AC B8R1U9.1
#=GS W6UKP4_ECHGR/37-166       AC W6UKP4.1
#=GS G3DRD2_9PAPI/162-590      AC G3DRD2.1
#=GS Q8UZ18_PSPVP/203-633      AC Q8UZ18.1
#=GS A0A077RCS4_ECHMU/43-226   AC A0A077RCS4.1
#=GS C6ZDA0_9PAPI/214-639      AC C6ZDA0.1
#=GS B2KKW8_9PAPI/178-609      AC B2KKW8.1
#=GS VE1_BPV5/184-617          AC Q705G8.1
#=GS A0A077RCT5_ECHMU/71-255   AC A0A077RCT5.1
#=GS D5FL27_9PAPI/171-601      AC D5FL27.1
#=GS B5SPY2_9PAPI/164-588      AC B5SPY2.1
#=GS B7TQN9_9PAPI/165-588      AC B7TQN9.1
#=GS A0A068XTH8_ECHMU/186-360  AC A0A068XTH8.1
#=GS U6FUW9_ECHMU/229-399      AC U6FUW9.1
#=GS A0A068XWU9_ECHMU/192-374  AC A0A068XWU9.1
#=GS Q647H9_9PAPI/169-598      AC Q647H9.1
#=GS VE1_HPV05/170-597         AC P06920.2
#=GS VE1_HPV1A/172-603         AC P03111.2
#=GS Q5IRF4_9PAPI/168-595      AC Q5IRF4.1
#=GS A0A077R414_ECHMU/2-157    AC A0A077R414.1
#=GS W5QK93_9PAPI/208-638      AC W5QK93.1
#=GS A0A0A7RZ37_9GAMM/181-334  AC A0A0A7RZ37.1
#=GS F2X1C4_9PAPI/189-620      AC F2X1C4.1
#=GS Q0QIH9_9PAPI/225-656      AC Q0QIH9.1
#=GS Q8JJG5_PEPVA/245-675      AC Q8JJG5.1
#=GS A0A0J7KFY5_LASNI/204-634  AC A0A0J7KFY5.1
#=GS A0A068Y0E1_ECHMU/192-277  AC A0A068Y0E1.1
#=GS F2VIS1_9PAPI/181-611      AC F2VIS1.1
#=GS A0A068Y0S4_ECHMU/105-269  AC A0A068Y0S4.1
#=GS A0A068Y0J2_ECHMU/229-397  AC A0A068Y0J2.2
#=GS VE1_COPV6/161-588         AC Q89536.1
#=GS Q1I125_9PAPI/138-566      AC Q1I125.1
#=GS C0ITA7_9PAPI/4-435        AC C0ITA7.1
#=GS U6HHE5_ECHMU/45-217       AC U6HHE5.1
#=GS VE1_CRPVK/162-593         AC P03112.1
#=GS VE1_BPV3/174-604          AC Q8BDD7.1
#=GS A0A068XWQ7_ECHMU/72-255   AC A0A068XWQ7.1
#=GS G3BER3_CANTC/1-57         AC G3BER3.1
#=GS Q6BLT1_DEBHA/1-56         AC Q6BLT1.2
#=GS VE1_PAPVE/170-602         AC P11328.1
#=GS B7P8E5_IXOSC/1-170        AC B7P8E5.1
#=GS Q5UUY3_9PAPI/173-602      AC Q5UUY3.1
#=GS G7YUC3_CLOSI/298-418      AC G7YUC3.1
#=GS E0SH87_DICD3/267-473      AC E0SH87.1
Q8QQC0_ECPVO/176-606                 ......................................................................................l-FKDAFGVPYGELTRQFRSDKTGCFDWVVAAY.AVREPFFESGKAQLRQHCRYTHVTYRPMPRG.TVLLMLVSFNNQKCRDTVNKLIRTLFNVHELLLMLEPPKIRSVAAAMYWYKQSLTNATETFGELPEWIKKLILINHQ.TDEEVKFDFSQFVQWAYDNEYQEEHEIAYNYASIADEDSNAAAWLGLTGQAKVVK.DVATMVR..Y..YRRAEM..NRMSMSNWIHNRKKK-...S....KPGQW....QPIVNFLK.Y....Q....GVA....MVTFINALKS.F.L..K.G..T.P.KK.NCLVIWGPPNTGKSWFCMSLM.H.F..L..G..GRVLSH...VN.S..NSHF..WLQPL..GDA..KVA.....LLDDATTVVWDYF.DRYMRNACDGNPISLDMKHKAP.VQIK...CPPL.LITSNID.......VK..A....D...DR.....W.....LYLHSRLVTFHFPNLF.PFEDDGSPVYQFNDENWNSLFTRLWRALDLSDQEDEG..D..DGDPAPAFRC..................................................
VE1_MNPVA/162-593                    ......................................................................................v-FKEAYGVSYKELTREYKSDKTCNPDWVIALY.SLSEPILNAARTTLQGICEYVFMQSRPTAAA.TVALLTVRFKCSKSRETVRKQMCGMFHSDPLLCLCDPPKVQSVPAALYWYKSSMYSGTFTHGEAPEWIKRQTMITCA.-MEETKFDLSEMVQWAYDNNYEDESQIAFEYARTATESPNANAWLASNAQAKHVR.DCATMVR..H..YKRAEM..KAMSMSQWVWKCCREE...P....EEGTW....TPISLYLA.S....E....GVE....VIRFLSAMKS.W.L..R.G..I.P.KK.NCLVFYGPPNTGKSLFTMSLI.K.F..L..R..GRVISF...AN.S..KSHF..WMQPL..AEA..KVV.....LLDDATRATWDYV.DTYMRNAMDGNPLSIDCKYRTP.VQVK...CPPM.LVTTNED.......VH..L....N...DR.....W.....RYLHSRIQVFHLKEPM.PIDTAGNPEYSFSNRHWKAFFEKLQKPLDLSEDEGDP.kD..NGEHTQPFSC..................................................
B4XYE1_9PAPI/200-630                 ......................................................................................l-FKEIYGCSFADLTRCFKSDRTVCEDWICLIA.GVPCSLVDAITELLKPHASYTHVTCTPCKVG.MLLLLLVQWKTNKNRETVANLLGGLLQVQKQQMLLEPPRIRCPAAAMFWYKKSMCNGTVVSGEMPQWILKQVSIQEQ.LGNIPPFQLSLMIQWAYDNGYDTESRIAYEYAALANEDKNAEAFLRSNSQAKFVK.DCACMVR..H..YKKAEM..DKMSIGQWIKHRCEKI...A....GDGDW....RPIMKFLK.Y....H....SVE....IMPFLMFFRR.F.L..K.G..I.P.KS.NCLVLYGPANSGKSYFAMSLI.N.M..L..G..GKVISH...VN.A..KSHF..WLQPL..ADG..KIA.....LLDDATPSTWDYM.DTFLRNLLDGNTISLDTKHKAP.LQIR...SPPL.IVTTNYN.......VL..E....N...EK.....W.....KYLHSRIKQISFLNPC.PLDCRGDPEIKLNNQNWKAFFEKCWARLSLDDLLEEG..-..DGETMQPLRC..................................................
V9P8E0_9PAPI/174-603                 .......................................................................................RFKKILGIGFTDITRTYKSNKTCAAEWVVSLH.DCNEVLSESLKTTLVEHCIFFQHIYTCTDEG.SVLLMLLRFRSQKSRDTVQNLFRSLLG--QMDMLADPPKIRSVPAALYWYKRSMSSTSYMHGSFPEWILQHTMLSHL.LGEEKPFELSVMVQWAYDNGYADESRIAYQYALLGDTDENAKAFLASNAQAKYVK.DCAAMVR..H..YLRAEM..AELSMSAWIYRRLEPI...E....DGGDW....REIVKFLR.F....Q....EVG....FIPFCIAFKK.F.L..R.G..T.P.KH.NCIVFYGPPNTGKSMLCMSLL.N.V..L..G..GKVISY...AN.S..RSHF..WLQPL..ADT..KIG.....LLDDATKACWDYM.DVYLRNALDGNPISVDCKHRAP.QQIK...CPPL.LITTNVD.......VM..S....D...DR.....W.....RYLHSRLTAFNFKNQF.PFDSEGNPGFALTDANWKSFFTRFWLQLELSDQEDEG..D..DGNSQQPLRL..................................................
E2E2D0_FCDNV/348-518                 ...............................................................mmfniidnmrvesrpktipiiskn--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....--------.-....-....--K....TVQWIQDFMD.I.I..H.G.nL.P.KI.NCMMLYGNSNSGKTQLIEALT.G.L..V..N..TAIMTN...VG.D..GGTF..HFSNI..TEM..STI.....VVGNETKIRTQTI.EQW-KGLCGGENVTMPMKYKEHkTHMF...RKPV.FLTNQ--.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------hhplvdishyddrraienrsfmykvelgse....................
Q30BJ1_9PAPI/164-591                 .......................................................................................QFKEAFGVSFTDLTRSFISNKTCTQHWVVAVF.GPNSDILDGTGTLLEPHCTFLLKCTCFADRG.PIILLLIEFKASKCRDTVQNLLNNIMRVEHHQMLLEPPKIRSQLTAFFFYKKTMAGGCDVIGKLPDWLTRLTVLSHQ.-GATEAFELSRMVQWAYDNDMLEDSEIAYYYAQHADVDSNAAAWLKTNNQAKYVR.DCGNMVR..L..YKQQEM..KNLTMSEYIYKRCCKV...E....GSGDW....KHIFKLLR.Y....Q....DVN....MIQFLTSFRD.L.L..S.C..K.P.KR.QCLVIYGPPDTGKSYFLYSLI.S.F..L..K..GKVISF...TN.S..KSHF..WLQPL..LNA..KVA.....LLDDATKACWNYM.DCYMRTALDGNAVSVDSKFKAP.VQVR...LPPL.LISTNVE.......LP..L....L...EE.....Y.....KYLHSRTMCYCFAKPC.LYDDEGNPLFNLTDRHWKGFFLHLEQQLGLNFSEKDE..-..--EASGAFR-c.................................................
D6YRN6_WADCW/13-73                   ..................................................................ieriflgfaveaqkqmsediy--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....--------.-....-....---....----------.-.-..-.-..M.P.KK.KVIVLSGPTACGKTEFAIELA.K.S..L..N..GEIIS-...--.-..----..-----..---..---.....-------------.----------------------.----...----.-------.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------adsmqi............................................
E7C0H2_9PAPI/176-608                 .......................................................................................RFKDVFGVSYTELTRPFRSDKTVCRDWVVAVY.GVREAVYESIKVQLEPLCDYMHLILRPTTQQ.NYLQALLQWKAQKSRETVRKLLKSLLQVDELQMLIDPPKLRSLPAALYWYKTALGNSCYTVGTAPDWVVRQTTVSHQ.-DEEARFDFSQMVQWAFDNNYDTECQIAYHYASIAAEEPNAAAWLSCSSQAKMVK.DCCTMVN..H..YKRAIM..REMTMSAWLNHKMKQV...S....VSGHW....REICGFLK.Y....Q....QVG....IPDLLSFLKL.F.L..K.G..T.P.KR.NCLVIAGPPDTGKSLFCMSLL.H.F..A..G..GKVLSY...AN.S..KSHF..WLQPM..LDA..KMV.....LLDDATKPCWDYM.DTHLRNLFDGNPVSVDAKHKAL.QQMK...CPPL.LITTNEM.......VH..K....N...ER.....W.....RYLHSRIKVIEFQNQC.PLDDNGEPAYKLNDGSWKSFFQRLWPHLDLSDQEDEG..DeeDGGPANTFRC..................................................
VE1_HPV11/211-640                    .......................................................................................KFKDCFGLSFVDLIRPFKSDRTTCADWVVAGF.GIHHSIADAFQKLIEPLSLYAHIQWLTNAWG.MVLLVLIRFKVNKSRCTVARTLGTLLNIPENHMLIEPPKIQSGVRALYWFRTGISNASTVIGEAPEWITRQTVIEHS.-LADSQFKLTEMVQWAYDNDICEESEIAFEYAQRGDFDSNARAFLNSNMQAKYVK.DCAIMCR..H..YKHAEM..KKMSIKQWIKYRGTKV...D....SVGNW....KPIVQFLR.H....Q....NIE....FIPFLSKLKL.W.L..H.G..T.P.KK.NCIAIVGPPDTGKSCFCMSLI.K.F..L..G..GTVISY...VN.S..CSHF..WLQPL..TDA..KVA.....LLDDATQPCWTYM.DTYMRNLLDGNPMSIDRKHRAL.TLIK...CPPL.LVTSNID.......IS..K....E...EK.....Y.....KYLHSRVTTFTFPNPF.PFDRNGNAVYELSDANWKCFFERLSSSLDIEDSEDEE..-..DGSNSQAFRC..................................................
VE1_HPV04/163-590                    .......................................................................................KFKEWYGVSYNEITRIYKSDKSCSDNWVIVIF.RAAVEVLESSKIVLKQHCTYIQVKI----FG.FSALYLVQFKSAKSRETVQKLMCSILNIQEYQMLCDPPKLRSVPTALYFYKHAMLTESSVFGQTPDWIAKQTLVSHQaATTAETFELSRMVQWAYDNNYVDECDIAYHYAMYAEEDANAAAYLKSNNQVKHVR.DCSTMVR..M..YKRYEM..RDMSMSEWIYKCCDEC...S....EEGDW....KPISQFLK.Y....Q....GVN....ILSFLIVLKS.F.L..K.G..I.P.KK.NCIVIHGPPDTGKSLFCYSFI.K.F..L..K..GKVVSY...VN.R..SSHF..WLQPL..MDC..KVG.....FMDDATYVCWTYI.DQNLRNALDGNPMCIDAKHRAP.QQLK...LPPM.LITSNID.......IK..Q....E...QS.....L.....MYLHSRIQCFNFPNKM.PILDDGSPMYTFTDGTWKSFFQKLGRQLELTDPEEEN..-..NGVPSRTFRC..................................................
Q0QLX4_9PAPI/188-619                 ......................................................................................l-FKKGYGISLTELTRVFKSNKTCNPDWVVVAF.GVHHNTYSDLVHRLEKHCEYVQCSGNAIATG.YIVLMLLRFTAHKNRNTLIKLMKSVLSVSDIQILADPPKIRSVPAALYWYRNSMSTAVQSHGPLPDWVARQTLVQHH.SGEDNKFVLSTMVQWAYDNDHTEESDIAYHYALLADEDTNAAAWLGTNSQAKHVR.DCAVMVK..H..YRRAIM..SAMSMSEWINRRMGLI...E....EEGDW....KNIGNFLR.Y....Q....GIE....VITFIGALRD.M.L..K.G..I.P.KR.TCMCIVGPPDTGKSAFCLSLL.D.F..F..G..GRVLSF...TN.Y..KSQF..WLQPL..ADT..RIA.....LIDDATKSTWDYI.DEYMRNALDGNAICVDLKHKNP.LQIR...CPPL.LITSNIN.......IK..H....N...DR.....W.....RYLYSRIHIVEFKHAF.PFNEEGEPVYQLTKGNWKSFFKRLWLRLDLSDQEDEG..E..DGEPEKTFRC..................................................
Q8JNA6_FCPVN/248-679                 ......................................................................................a-FKKMYNASYYEVAREYKSDKTQSYEWVLFML.GCSPERVSALNECLKGVTEFILYDC--NPTD.YSALFYLEFYCSKNREGVRRLLKNYNVDTDSILLLNPPNKRSVLAALFYQKLVL-----AHGDFPDWCRD-ILSNEQ.-LSGEGFELSQMIQWALDNKHHDEGSIAYHYAIHAEQDNNAKLWLQSNQQAKYVR.DAATMVR..H..FVKGRL..HSITMSEHIAAQIREY...DvestDEDGW....KKILVFLT.F....Q....HIN....FKEFISILCM.W.L..K.G..R.P.KK.SCITIAGVPDSGKSMFAYSLI.K.F..L..N..GSVLSF...AN.S..KSHF..WLQPL..TEC..KAA.....LIDDVTLPCWDYV.DTFLRNALDGNAICIDCKHRAP.VQTK...CPPL.LLTSNYDprlhgvdSG..G....G...NR.....Y.....KYLNSRIQFLLFNRVI.PLY-GTQPRFYIEPADWRSFFQKYSEDLQLQITEYDG..S..QAA-------setppa............................................
VE1_HPV41/178-605                    .......................................................................................KFKAVYGVSFTDITRPFKSDKTTSQHWVVAAYyLAFDSEISAMEVLLRQQCQFLYIDN----ND.GIILFFLEYNVQKSRTTVYNWFTANFHYNENRMLANPPRTRNMPAALFFYHRFMGTGGIKHGAMPEIIVNQCVVSNQ.--QTDTFELSRMVQWALDNDLQDEHMLALEYALLAESDGNARAFLKQNNQPMIVK.NCSIMVR..H..YKTALV..AKMSISQYVNKRCLDH..gE...aDENSW....RGIVHFLR.Y....Q....GQE....FLPFMCKMHN.F.L..H.H..R.P.KK.STLVLCGPSDTGKSYFANGLN.K.F..L..D..GHVLSF...VS.N..GSHF..WLSPL..RGA..RCC.....LIDDATLTFWRYA.DQNMRALLDGYEISIDAKHRNP.MQTR...APPL.IITTNED.......IM..R....L...DE.....F.....KYLQTRTMYVYFNKPF.PLKGNGQPLYYIDGYTWNSFFRKFWRHLNLKDPEDES..-..DGETPGTIR-l.................................................
VE1_HPV16/210-640                    .......................................................................................KFKELYGVSFSELVRPFKSNKSTCCDWCIAAF.GLTPSIADSIKTLLQQYCLYLHIQSLACSWG.MVVLLLVRYKCGKNRETIEKLLSKLLCVSPMCMMIEPPKLRSTAAALYWYKTGISNISEVYGDTPEWIQRQTVLQHS.-FNDCTFELSQMVQWAYDNDIVDDSEIAYKYAQLADTNSNASAFLKSNSQAKIVK.DCATMCR..H..YKRAEK..KQMSMSQWIKYRCDRV...D....DGGDW....KQIVMFLR.Y....Q....GVE....FMSFLTALKR.F.L..Q.G..I.P.KK.NCILLYGAANTGKSLFGMSLM.K.F..L..Q..GSVICF...VN.S..KSHF..WLQPL..ADA..KIG.....MLDDATVPCWNYI.DDNLRNALDGNLVSMDVKHRPL.VQLK...CPPL.LITSNIN.......AG..T....D...SR.....W.....PYLHNRLVVFTFPNEF.PFDENGNPVYELNDKNWKSFFSRTWSRLSLHEDEDKE..N..DGDSLPTFKC..................................................
C5L5M0_PERM5/18-129                  .................................................................................escrqk--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-----------------------------------------------NLQVMFVI.NKIDGIP..F..YEK---..KKHQIRQWATRMSRQI...K....-NAQW....SDVVLVSS.L....N....GTG....FAELEDRMRQ.Y.L..S.A..-.D.KP.RWIYIVGRVNTGKSTFVNRWL.R.H..I..G..------...--.-..----..-----..---..---.....-------------.----------------------.----...----.-------.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------ythlgtvnykr.......................................
A0A075B0T7_9FUNG/28-237              ..................gcannvsvmfgslpakvsrasssnaitmiqfyqianeynfvddtslyafiqqhvtsqdptlqsnalklq--------------------------------.-------------------------------.-----------------------------------------------------------------------------.------------------------------------------QFVNKNSFSKSMRiRVDEAIRwgHatYKEL-R..RQKSRMQLLAEACP-V...E....RPNDV....DNIYRILH.N....H....NVD....IFNFRTVLLK.Y.I..F.EdvS.N.AK.KRLCIIGPSNTGKSRILQGIA.D.I..L..N..TE--TF...IN.E..HTVY..KFKPL..LNA..ELI.....VI-----------.----------------------.----...----.-------.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------pelqkll...........................................
B8R1U9_9PAPI/162-593                 .......................................................................................KFKDLVGVSFTELTRTFRSNKTCYTDWVVCVY.GVSGPVSLTAPSLLTPHCEYLNLTVHGGRGA.ILVVFLARFKTSKSRETVCKLVKALMDVKDAQIMAQPPKVKSVPAALYWYKCGIGNGGVVHGPHPEWILQQTMISHK.TGEEARFSFGDMVQWAYDNDFRDECQIAYEYARLATEDSNALAWLECNNQAKFVK.DCARMVG..Y..YKRAEM..QNMSISAWIHKQIKDR...Q....CTTDW....KVILNFLK.F....Q....HVE....VIIFLNAMMH.L.L..R.G..T.P.KK.NCLVLYGPPNTGKSMFAMSLI.Q.C..L..K..GRVLSY...VN.S..RSQF..WLQPL..ADA..KIA.....LLDDATRPCWDYI.DINLRNALDGNPICLDCKHRAP.VQIK...CPPL.IVTTNVD.......IQ..A....D...AR.....W.....RYLWSRVRVFKFGSDM.PLNDDGTPTYNITDAHWQSFFQRLWKQLDLSDQEDEG..D..DGETGEPLRC..................................................
W6UKP4_ECHGR/37-166                  .....................................................................hppgsgsesiqwledmfl--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....--------.A....N....EIA....LVDFAITLRI.I.M..N.C..EdE.KI.NTLVLYGPTNTGKSLICKLTT.T.F..L..E..HGSVMR...RQ.G..ASAF..AYENL..LNR..KVA.....LMEEPG-------.----------------------.----...----.-------.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------icaanqqdlkqilggetfkgpkdmqttqqapqp.................
G3DRD2_9PAPI/162-590                 ......................................................................................i-FKQNFDISFGELSRPFKSAKTCYGEWVVAVY.GVQQVLYESLQTTLASHCSYMHLSYSSKEKH.SITLALLTFKTMKCRDTVIKLFKTLLNVQEMQILAEPPKVRSVAAALFWFKTSLFKSAQCTGPLPEWIARQTNFNQL.-VEETKFDLSTMIQYAYDHDMVEESTIAYNYARLADTDGNAAAWLASSNQAKYVR.DCCTMVR..H..YKRAEM..RNMTISAWIHKRCKSV...G....-DADW....KQIARFLK.L....Q....NVE....FMPFVQILKQ.F.L..R.G..I.P.KK.NCLLFYGQPNTGKSMFTMSLI.Q.F..L..H..GKILSF...LN.S..KSQF..WLQPL..ADC..KIA.....LIDDATENCWSYI.DVYLRNALDGNPICIDCKHKAP.LQIK...CPPL.LITSNID.......IS..T....N...SK.....W.....FYLHSRIHGFKFDVPI.P-DIDGKPQFTLTDEHWKCFFARLWTHLELSDQEEDS..D..NGDSQETFRC..................................................
Q8UZ18_PSPVP/203-633                 ......................................................................................l-CKDAYGCSFSDLTRSYKSDKTVCGDWVCLIA.GVPCSLEEAITDLLKPHSDYTHVNISTCRYG.LLLLLLVRWKTAKCRETVQKLLGGLMSVEKHQMVLEPPKIRHPATAMFWYKRTLANASVVTGETPEWILKQVSLQEQ.IGAAATFSLSAMVQWAYDNGLEGESEIAYGYAQLAEEDTNAEAFLRSNAQAKHVK.DCAIMVR..H..YRRAEM..CKMNIAQWIKLRCSKV...E....GEGDW....RPIMKFLK.F....Q....KVE....ILAFLTFMRH.F.L..R.G..T.P.KR.NCMVLLGPPNTGKSLFGMSLM.H.F..L..G..GKIISH...VN.S..GSHF..WLQPL..LEC..KVA.....MLDDATTSTWDYM.DIYLRNMLDGNTVCLDAKHKAP.MQLK...CPPL.IVTTNVD.......VT..A....N...DK.....W.....KYLHSRLKVFTFPNLC.PLNCRGDPEFQLTPENWKAFLEKCWTSLGLEDLLKDG..-..DGEPLQPLRC..................................................
A0A077RCS4_ECHMU/43-226              .....................................................................knhsgpsrkesiqwledm--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....------FS.A....N....EIA....VVDFAITLRI.I.M..N.C..EdE.KI.NTLVLYGPTNTGKSLICRLTT.S.F..L..E..HGSVMR...RQ.E..ASAF..AYENL..LNR..KVA.....LMEEPKICAAN--.QQDLKQILGGEPFEVHIKYQNP.DLLE...RLPV.IVTTNEP.......L-..-....-...--.....-.....----------------.-------------------------------------..-..----------gvrlsdvdaaaiegrckiytldkqicnanidgsvpappyklc........
C6ZDA0_9PAPI/214-639                 ......................................................................................v-FKEAYGASYTEVTRTFKSDKTQSNEWVFVIL.GCATVVYEALRECLQAHTDFLLVDCDPCR--.RLGLFYCGFPVSKNRDGVRRLLKHFNIDHPNVPLMDPPNKRSTLAALFFQKLVL-----VHGEVPQWCRDITGMSQL.--SGDQFELSKMIQWALDNNYSDEGAISFHYAIQAETDMNAQLWLKSNSQARFVR.DCAAMVR..H..YKRGQL..HAMDMEEFIASRVKHF..aD...aSDEGW....KPILVFLR.F....Q....HVP....LPDFLQMLRY.W.L..K.G..R.P.KK.STIAIVGVPDSGKSMFCMSLN.Q.F..L..D..GRVLSF...SN.S..KSHF..WLQPL..SEA..KTA.....LIDDLTRPAWDYL.DIYLRNALDGNPISIDCKHRAP.MQIK...CPPL.LLTSNVD.......PR..A....P...DStgcagY.....KYLTNRIAFITFGRPI.PLR-DGAPRFLIEPGDWKAFFDKFQVELDLTLQKYD-..-..----------cgerspase.........................................
B2KKW8_9PAPI/178-609                 .......................................................................................KFKEVYDISFKDLTRPFKSSKTCNSDWVVAVF.GVHESVCEGSIELLKKHCTYVHLQKELSSWG.NVLLLLLCFTTAKNRTTVEKLLCSVLACNQQLLMADPPKVRSAAAAVYWYKAGFTNHATQWGEKPKWIMQHVGLQHI.AADQIPFDLSVMIQWAYDNGYQDECEVAYEYARLADTDTNASAFLKSNCQAKYVK.DCVTMVR..L..YKRAEM..SRLNMRQWIEKRREEV...D....GDGDW....RTIVTFLK.Y....Q....NVE....FVPFMQKFKM.L.L..K.G..V.P.KK.NCMVFVGPPNTGKSAFCMGLL.K.F..M..Q..GRVISF...MN.S..RSHF..WIQPL..QDA..KLG.....LLDDATDACWDFF.DVYMRNALDGNPISIDRKHKAP.IQMK...CPPL.LVTTNVD.......VT..N....N...DR.....W.....KYLHSRLVTVRFPNEF.PITDEGEVVYKFTEQNWKSFFGRLWARLDLSDGEEEG..D..DAEPQQPFRC..................................................
VE1_BPV5/184-617                     ......................................................................................v-FKFVYAASFCDLTRPFKNDKTTNYQWVAAVF.GVSEELFEASKQLLGRSCTYLHATCRAHEKG.SVALLLLSFHVAKSRETVTNLLKNLLNLRAEHMMLQPPKLRGVTSAMFWYKMTLSPNTYTWGQLPRWIEQQILITEN.SSEVLKFDFSHMVQWALDNEMMDESSIAFHYAQMADHDSNARAWLGLSNQAKIVK.DVCTMVH..H..YQRAIM..RSMTMSAYVHKMCERV...N....VTGSW....LVIMQFLK.F....H....GIE....PIRFVNALRP.W.L..Q.G..V.P.KK.NCLAFIGPPDTGKSLFTNSLM.S.F..L..K..GKVLNF...AN.S..ASHF..WLAPL..TEA..KVA.....LIDDATHACLKYC.DTYLRNFFDGYSVCIDRKHKNA.VQIK...APPM.LLTSNID.......IQ..A....E...EK.....Y.....SYLKSRVTCFYFNDKC.PLNEDGKPLFQITDPDWKSFFERLWQRLELSDQEEEEegD..ENGSRGTFIC..................................................
A0A077RCT5_ECHMU/71-255              ....................................................................pknhsgpsrkesiqwledm--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....------FS.A....N....EIA....VVDFAITLRI.I.M..N.C..EdE.KI.NTLVLYGPTNTGKSLICRLTT.S.F..L..E..HGSVMR...RQ.E..ASAF..AYENL..LNR..KVA.....LMEEPKICAAN--.QQDLKQILGGEPFEVHIKYQNP.DLLE...RLPV.IVTTNEP.......L-..-....-...--.....-.....----------------.-------------------------------------..-..----------gvrlsdvdaaaiegrckiytldkqicnanidgsvpappyklc........
D5FL27_9PAPI/171-601                 ......................................................................................i-FKQVVGVGFGELTRQFKSDQTCAGHWVCAGF.GVLEEVYEAFKQSLKPLVTYYNVSRFPFEKG.SVTLILATFKVNKSRATVQKLMKTLLQVEDYMVVSSPPRLRSAVTACFWFRRGFTSTCTTYGEMPEWLKKQILVSHQ.SKEEATFSLTAMVQWAWDNEVCDEATAAYEYAKLCNDDSNAAAFLNSNNQPKHVK.DCIAMVR..M..YRTAEM..RGMTMSAWISRRAKKI...V....GEGSW....KDIVNFLR.Y....Q....SVE....MPVFIGCLRA.C.L..K.K..V.P.KK.TCLVIAGPSDTGKSTFLLSLM.R.F..M..Q..GAVLSF...VN.Y..RSHF..WISPL..AHC..KVA.....LIDDATPQCWDYL.DTYMRNALDGTEISLDLKHRNH.QQIV...CPPL.FISTNCD.......LQ..Q....E...DK.....W.....KYLRSRLSLFTFANKF.PLDDSGNPLYVLNEANWKAFFLRLWSHLELSDQEEDS..-..DGEAKSPFR-r.................................................
B5SPY2_9PAPI/164-588                 .......................................................................................QFKERFGISFCDLTRPFKSNKTTCGDWVVYAC.GMSDALADATSDLLSPHCIYGNITKEHSALG.NSLLMLLRFTHAKNRDTLTKLLGSHMTIPAYNIVAEPPKIRCPAAAIFWYRRSTTQGVTVFGDVCEWITKQVTVGGG.---ECAFELSTMIQWAYDSDLTDEAQVAYEYAKLADSDRNAEAFLKSNCQAKYVK.DCCTMVR..L..YKKAEM..HNMTMGQWVRKQADRY...E....GEGNY....RPIVQFLK.F....Q....GIE....FIPFMHTLAQ.F.L..K.G..I.P.KR.NCLVIHGPPNTGKSLFTMSLC.S.F..L..G..GKVISF...VN.S..KSHF..WLQPL..GEC..KVA.....LLDDATRPCWDYF.DLYLRNLLDGNPVSLDAKHRAP.IQIK...GPPL.LITSNVG.......IS..T....E...DR.....W.....KYLHSRVRCFSFPNTL.PLDSKGDPVYELTALNWKSFFTRLWSRLDLKEGSH--..-..----------geaftalrc.........................................
B7TQN9_9PAPI/165-588                 .......................................................................................KFKDTYGVSFTELSRLFKSNKSCCTDWVLSVY.GVSTELIEASKQLLQQSCLFIYLYV----SG.FIALYLLRFKAAKNRDTVLKLITKVLYCKPEQVVADPPKTRSVPAALYWLKTSTGP-GWTYGILPEWISNQTLVSQA.--TKDVFDFSQMVQWAYDNDFDEESVIAYNYALFADEDPNARAWLACLGQAKHVK.DCATMVR..Y..YKRAEM..KEMTMSAWIHKQLQKV...E....-TGQW....QEIVRFLR.Y....Q....EVT....FIRFLGVLKN.V.L..K.G..I.P.KK.NCMVLYGPPNTGKSMFAMSLV.H.C..L..R..GKVISF...CN.S..KSHF..WLQPL..VDA..KLG.....LLDDATDACWSYI.DTYLRGGLDGNPVSIDCKHKSL.AQLK...FPPL.IITTNCD.......LT..A....D...DL.....Y.....LYLRSRIQLIQFPNPF.PFDENGNAGFELSDRSWKAFFKKLWTQLELSDQEDEG..E..DGEANATFRC..................................................
A0A068XTH8_ECHMU/186-360             ..................................................................caypknhsgpsreesiqwled--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....-----MFS.A....N....AIA....VVDFAITLRI.I.M..N.C..EdE.KI.NTLVLYGPTNTGKSLICKLMT.S.F..L..E..HGSVMR...RQ.E..ASAF..AYENL..LNG..KVA.....LMEEPKICAAN--.QQDLKQILGGEPFEVPVKYQNP.DLLE...RLPV.VVTTNEP.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------lgvrlsdvdaaategrckiytldkqicnan....................
U6FUW9_ECHMU/229-399                 ...................................................................ypknhsgpsrkesiqwledm--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....------FS.A....N....AIA....VVDFAITLRI.I.M..N.C..EdE.KI.NTLVLYGPTNTGKSLICKLMT.S.F..L..E..HGSVMR...RQ.E..ASAF..AYENL..LNR..KVA.....LMEEPKICAAN--.QQDLKQILGGEPFEVHTKYQNP.DLLE...RLPV.VVTTNEP.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------lgvrlsdvdaaategrckiytldkqicn......................
A0A068XWU9_ECHMU/192-374             .....................................................................knhsgpsrkesiqwledm--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....------FS.A....N....EIA....VVDFAITLRI.I.M..N.C..EdE.KI.NTLVLYGPTNTGKSLICRLTT.T.F..L..E..HGSVMR...RQ.E..ASAF..AYENL..LNR..KVA.....LMEEPRICAAN--.QQDLKQILGGEPFEVHIKYQNP.DLLE...RLPV.IVTTNEP.......L-..-....-...--.....-.....----------------.-------------------------------------..-..----------gvrlsdvdaaaiegrckiytldkqicnanidgsvpappykl.........
Q647H9_9PAPI/169-598                 .......................................................................................KFKGCFGVSLKELTRPYKSSKTCCNEWVVFAF.GIREELLTASKTLLQPHCDFFLADIETGGLG.YVCLYLITFKAAKNRETITKLFCSMLNCYDYQLRADPPKNRSVAVALFFYKLGLSGGCFKHGDFPPWLAKQLLVSHQ.-QDMDVFELSKMVQWAYDNDHTDESEIAFHYACLADEDSNAAAWLKSNAQAKYVA.DCSKMVR..H..YKKQEM..RNMSMSQWIYRCCYLV...E...gHDGDW....TVVAKYLK.Y....Q....GVS....FLGFLTALRH.L.F..E.G..T.P.KK.QCLLIYGPPDTGKSWFCFSLL.N.F..L..R..GKVVSY...QN.S..RSHF..WLSPL..ADC..KVG.....MLDDATHACFQFI.DVNMRSAFDGNYVSVDCKHKAP.IQIK...LPPM.LVTSNVN.......LP..G....E...AC.....F.....QYLHSRVTGFEFPRKF.PIDQDGSPVFSLTHSVWKAFFKRLHHQLGL-DPEDEN..-..AGESCQAFRC..................................................
VE1_HPV05/170-597                    .......................................................................................KFKESFGVGFNELTRQFKSHKTCCKDWVVSVY.AVHDDLFESSKQLLQQHCDYIWVRG----IG.AMSLYLLCFKAGKNRGTVHKLITSMLNVHEQQILSEPPKLRNTAAALFWYKGCMGSGAFSHGPYPDWIAQQTILGHK.SAEASTFDFSAMVQWAFHNHLLDEADIAYQYARLAPEDANAVAWLAHNNQAKFVR.ECAYMVR..F..YKKGQM..RDMSISEWIYTKINEV...E....GEGHW....SDIVKFIR.Y....Q....NIN....FIVFLTALKE.F.L..H.S..V.P.KK.NCILIYGPPNSGKSSFAMSLI.R.V..L..K..GRVLSF...VN.S..KSQF..WLQPL..SEC..KIA.....LLDDVTDPCWIYM.DTYLRNGLDGHYVSLDCKYRAP.TQMK...FPPL.LLTSNIN.......VH..G....E...TN.....Y.....RYLHTTIKGFEFPNPF.PMKADNTPQFELTDQSWKSFFTRLWTQLDLSDQEEEG..E..DGESQRAFQC..................................................
VE1_HPV1A/172-603                    .......................................................................................RFKDTAGVSFTDLTRSYKSNKTCCGDWVLAVW.GVRENLIDSVKELLQTHCVYIQLEHAVTEKN.RFLFLLVRFKAQKSRETVIKLITTILPVDASYILSEPPKSRSVAAALFWYKRSMSSTVFTWGTTLEWIAQQTLINHQ.LDSESPFELCKMVQWAYDNGHTEECKIAYYYAVLADEDENARAFLSSNSQAKYVK.DCAQMVR..H..YLRAEM..AQMSMSEWIFRKLDNV...E....GSGNW....KEIVRFLR.F....Q....EVE....FISFMIAFKD.L.L..C.G..K.P.KK.NCLLIFGPPNTGKSMFCTSLL.K.L..L..G..GKVISY...CN.S..KSQF..WLQPL..ADA..KIG.....LLDDATKPCWDYM.DIYMRNALDGNTICIDLKHRAP.QQIK...CPPL.LITSNID.......VK..S....D...TC.....W.....MYLHSRISAFKFAHEF.PFKDNGDPGFSLTDENWKSFFERFWQQLELSDQEDEG..N..DGKPQQSLRL..................................................
Q5IRF4_9PAPI/168-595                 .......................................................................................RFNDMYGVKYTDLIRAFKSDKTMSANWVVVCYvPLLEDGKAAAKHTLQQQCSWYFMED----RA.GIQLFNVEFNAQKCRATVIKLFTKLFNFSSKRLMADPPKLRSAPACLFWYQKVLKKVGASYGELPDYIHTQCALGSG.--HVPVFELTKMVQWALDNNLTEESSIALKYAMLAEEDENAQAFLKSNNQPKLVK.DCCTMVR..M..FQTALM..RDMSISQYVDHRCNEV..tE...qVGEEW....RSIVHFLR.Y....Q....GVQ....FLSFMIDLKN.L.L..H.H..K.P.KK.CTIVVCGPPNTGKSYFVLSFV.K.F..M..N..GCVISF...VN.Y..GSHF..WLTPL..RTA..RIG.....MIDDATNSFWKYC.DTYMRTLLDGNDVSIDCKHRNP.IQLR...CPPL.VITTNED.......IK..N....D...PQ.....Y.....KYLQTRLRFLYFNKPF.PLHDRGDPVYKIESLQWASFFRKFWRHLDLTPLEEDT..-..HGETATPLR-l.................................................
A0A077R414_ECHMU/2-157               ...................................................................................fsan--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....--------.-....-....AIA....VVDFAITLRI.I.M..N.C..EdE.KI.NTLVLYGPTNTGKSLICKLMT.S.F..L..E..HGSVMR...RQ.E..ASAF..AYENL..LNR..KVA.....LMEEPKICAAN--.QQDLKQILGGEPFEVHIKYQNP.DLLE...RLPV.VVTTNEP.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------lgvrlsdvdaaategrckiytldkqicnanide.................
W5QK93_9PAPI/208-638                 .......................................................................................KFKECYGVGFTDLVRQFKSDKTCCWEWVVAAF.GMPVAVAESLKTTIQPLCTYAHIQTTTCSLG.GAVLILASFKASKNRQTVKKAMGTLMNIPEDRMLIEPPKLKSMPAALYWFKTSMSNVSEVFGEPPDWLKRQTQLNHC.-FEDDTFNLSHMVQWAYDNKYTDDSTIAYEYACIGDTDSNAAAFLKSNCQAKYVK.DCGVMVR..H..YLRAEM..RKMSMAEWIEHCSSKV...E....EDGDW....RTIVRFLR.Y....Q....GIE....FVSFCRALKD.F.L..K.G..V.P.KR.NCIVLCGPPNTGKSWFGMSLM.T.F..L..Q..GKVLSY...CN.A..ASHF..WLQPL..GDT..KIA.....MIDDATPQCWDYM.DTYMRNALDGNPICVDRKHKEP.TQIK...CPPL.LITSNTN.......IK..E....N...DR.....W.....RYLWSRHTMFMFPNEM.PFTPQGTPVYELSNANWKSFFGRSWAQLDLGDREDVQ..D..NGRANQPFRC..................................................
A0A0A7RZ37_9GAMM/181-334             .........laalymilanrydwqlflevtgaggsgksvfaeiatmlsgknntvigtmeslekardralvvgysliilpdqprymgs--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....--------.-....-....---....----------.-.-..-.-..-.-.--.---------------------.-.-..-..-..------...--.-..----..-----..---..---.....-------------.GAGLKAITGGDEVAIDPKHKQP.YSCK...IPAVvLVINNEA.......MR..F....N...DR.....N.....GGISRRRVIFHFSKVI.PEKE---------------------------------..-..----------rdlqlvskirq.......................................
F2X1C4_9PAPI/189-620                 .......................................................................................RFKEAYGVAYGELTRQFKSDKTCNGDWVVAVF.GASPILYEGTNLRLQKHCESSLLTNTQTAAG.AIALMLLRFKAQKSRDTLYKLLKGMLNVPEYQIMAEPPRIRSTPAAVYWFRLAMATSTQKHGELPEWVTRQTMLHHQ.TAEEQKFTLSTMVQWALDNDYTDECTIAYEYAKCADTDSNAAAWLNTNAQAKHLK.DCATMVA..H..YRRGIM..RSLSMSGWIHKRVQRA...P....DGGDW....RHIIQFIK.Y....Q....HIE....VIVFLTALTH.L.L..K.G..T.P.KR.NCVLLCGPPNTGKSTFAMSLL.S.F..M..G..GRVLSF...AN.A..KSHF..WMQPI..VDS..RLV.....LIDDATKNTWDYI.DEYLRNALDGNPICLDVKHRAP.TQLK...CPPI.LVTSNID.......IR..E....D...DR.....W.....RYLHSRVCCFKFINEF.PFNREGQPVYELDDKNWKCFFTRLWLQLDLSDQEDEA..D..DGGAGDTFRC..................................................
Q0QIH9_9PAPI/225-656                 .......................................................................................RFKEVYGVSVTDLTRQFKSDKTCCKNWVVVIF.GLCEPYYITLTGVLPDHCCYSHMQRAVSEQGgGIALMLCDFKAMKNRDTVIKLIKSLVPVSDDLIMVQPPNVRSPAAALYWVQRAQSNASECKGEYPSWITKQTMLSHM.LAEDVTFDFSNMVQWAYDQGYTEESKIAYHYAQLAEEDKNAMAWLSSAAQAQHVK.HCAQMVR..Y..YMQAQT..AEMTMAQYIHERIEQV...E....GEGDW....KHIIAFLR.H....Q....DIE....IIPWLRTTRD.W.L..K.G..I.P.KR.NCVCYHGPPDTGKSMFGMSLM.R.F..M..R..GAIISY...VN.S..RSHF..WLQPL..VSA..KVA.....MLDDATDACWQYI.DTNLRNLLDGNPLSFDLKHRAP.IQAT...CPPL.LITSNID.......IT..Q....D...DK.....H.....KYLRSRVKCFAFHCPL.PVGEDGMPTLVLTEASWKCFFRKFASTLEVALPEEEE..-..DGDSQRSFRC..................................................
Q8JJG5_PEPVA/245-675                 ......................................................................................v-FKELYTASFTEVTRTFKSDKTQSYEWVFMVL.GCSHIALEAVKDVLIHNTEHVILDI--DPYK.HLGVYYVGFTVSKSREGLLRFLKQHNIFTENVVLSNPPNKRSVLSALFFDKL-----VQVSGDKPQWMIDIITSGDK.--GGEGFELSKMIQWALDNNMYDEGAIAYNYALLADTDLNAQLWLKHNSQAKYVR.DAATMCR..H..YRRGQM..QAIGVMEHLATRMREYadsD....IEEGW....KRIIVFLR.Y....Q....HVD....HHTFINDLKY.W.I..V.N..R.P.KR.STIAIVGIPDSGKSMFGMSLI.Q.F..L..D..GRVLSF...SN.H..KSHF..WLQPL..SET..RYA.....LVDDVTWPAWDYM.DVYMRNALDGNPICIDCKHRAP.IQTK...CPPL.LLTSNYDpr..ergTG..A....E...NS.....Y.....RYLLSRITFMSFNRSI.PCI-GGQPRFLISPADWRSFMLKFRKELDIN------..-..----------ltdldyggatgepgetae................................
A0A0J7KFY5_LASNI/204-634             .......................................................................................KFKELYGVGYYELVRQFKSSRTACADWVVCAF.GVYYAVAEGIKQLIQPHTQYAHIQIQTSSWG.MVVFMLLRYNCAKNRDTVSKNMSMLLNIPEKHMLIEPPKLRSTPAALYWYKTSMGNGSEVYGETPEWIVRQTLIGHS.-MEDEQFKLSVMVQYAYDHDITDESALAFEYAQLADVDANAAAFLNSNCQAKYLK.DAVTMCR..H..YKRAER..EQMSMSQWIKFRGSKI...S....EEGDW....KPIVKFLR.H....Q....GVE....FVSFLAAFKS.F.L..K.G..V.P.KK.NCIVFYGPADTGKSYFCMSLL.Q.F..L..G..GAVISY...AN.S..SSHF..WLQPL..ADS..KIG.....LLDDATAQCWTYI.DTYLRNLLDGNPFSIDRKHKTL.LQIK...CPPL.MITTNIN.......PL..E....E...DR.....W.....KYLRSRVTLFKFTNPF.PFASPGEPLYPINNANWKCFFQRSWSRLDLNSPEDQE..D..NGNTGEPFRC..................................................
A0A068Y0E1_ECHMU/192-277             ......................................................................knhsgpsrkesiqwled--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....-----MFS.A....N....EIA....VVDFAITLRI.I.M..N.C..EdE.KI.NTLVLYGPTNTGKSLICRLTT.T.F..L..E.hGSVM--...--.-..----..-----..---..---.....-------------.----------------------.----...----.-------.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------rrqeasafaica......................................
F2VIS1_9PAPI/181-611                 ......................................................................................l-FKKTMGISFTDLSRTFQSDKTPCVDWVAVCF.GVPLSLIDACTELLQPHCEFGNVTTTPCCTG.YLLLLLARFQVAKCRVTVKKLLGNTLHVPEQQILTEPPKIRCPAAAIYWYKKGITGVAKTWGPLPEWLAKMVNVSSN.LADAAVFNLSDMIQWAYDNNKTEDADIAYGYAQLADTDRNAEAFLKSNSQAKYVK.DCGVMVR..L..YKKAEM..QRTSMKDWIKRRCEEV...D....GDGDW....RPIVSFLK.F....Q....GID....MAVFISVLKN.F.L..K.G..I.P.KQ.NCIVICGPPNTGKSLFSVSLI.Q.F..L..S..GKVISF...VN.S..KSHF..WLQPL..GEC..KVA.....LLDDATGPAWDYF.DTFLRNLVDGNPISLDCKHKAP.TQVK...CPPL.IITSNID.......VT..A....S...DR.....W.....KYLHSRLKLFTFSNPC.PLTEQGEPAFNLTPVNWKCFFKRLKTRLGLADDEGED..-..HGESQQPLKC..................................................
A0A068Y0S4_ECHMU/105-269             .....................................................................hsgparresiqwledmfs--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....--------.A....N....AIA....VVDFAITLRI.I.M..N.C..EdE.KI.NTLVLYGPTNTGKSLICKLMT.S.F..L..E..HGSVMR...RQ.E..ASAF..AYEDL..LNR..KVA.....LMEEPKICAAN--.QQDLKQILGGEPFEVHIKYQNP.DLLE...RLPV.VVTTNEP.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------lgvrlsdvdaaategrcksytldkqi........................
A0A068Y0J2_ECHMU/229-397             ...................................................................ypknhsgpsrkesiqwledm--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....------FS.A....N....AIA....VVDFAITLRI.I.M..N.C..EdE.KI.NTLVLYGPTNTGKSLICKLMT.S.F..L..E..HGSVMR...RQ.E..ASAF..AYENL..LNR..KVA.....LMEEPKICAAN--.QQDLKQILGGEPFEVHIKYQNP.DLLE...RLPV.VVTTNEP.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------lgvrlsdvdaaategrcksytldkqi........................
VE1_COPV6/161-588                    .......................................................................................KFKSSFGISFTDLTRVYNSDKTCSSDWVVCLY.HVSDDRREAGKTLLQDHCEYFFLHS----MG.FCTLLLLCLFVPKCRNTLFKLCRSLFHISNVQMLADPPKTRSPAVALYWYKKGFASGTFTHGELPSWIAQQTLITHH.LAAEKTFDLSEMVQWAYDNDLKDESEIAYKYAALAETDENALAFLKSNNQPKHVK.DCATMCR..Y..YKKAEM..KRLSMSQWIDERCKAT..dD....GPGDW....KEVVKFLR.H....Q....GIE....FILFLADFKR.F.L..R.G..R.P.KK.NCLVFWGPPNTGKSMFCMSLL.S.F..L..H..GVVISY...VN.S..KSHF..WLQPL..TEG..KMG.....LLDDATRPCWLYI.DTYLRNALDGNTFSVDCKHKAP.LQLK...CPPL.LITTNVN.......VC..G....D...EK.....F.....KYLRSRCSFFHFPQEF.PLDDNGNPGFQLNDQSWASFFKRFWKHLDLSDPEDGE..-..DGETQRGLRL..................................................
Q1I125_9PAPI/138-566                 ......................................................................................i-FKQTYGVTFASLTRVFKSDKTCCHNWVVCVF.SASEEVIEGSKIQLRQYCDFYYASVLLCKKG.HCVLYLLDFKASKNRETVIRLFTSMLAVPDHCILSDPPKLKHVPAALFWLKTSNQPHVAVHGQLPNWICQQTMLNYE.-NQQPQFELRKMVQWALDHNLTDDSMIAYNYAQLAEEDENANAWLNSNSQARYLK.ECALMTR..H..FLRAQR..LEMTMAKWLTRCITSV...R....GNGDW....KAIIKFLK.Y....Q....NVN....IVNFLSMFRD.F.M..N.S..K.P.KK.NCLVICGAPNTGKSIFAMSLM.Q.F..L..Q..GKTISF...AN.H..KSHF..WLQPL..ADC..KFA.....VLDDATLPCWSYL.DIYCRNALDGNYVCIDSKHKNP.VQIK...IPPL.LITTNYN.......IL..Q....E...DK.....F.....FYLHSRLLFLEFNNAF.PLDEEGNPQFDLNDQNWKSFFIKLRRQLDLEDIEEEE..E..ND--------slgstv............................................
C0ITA7_9PAPI/4-435                   .......................................................................................RFKTCFEVGFNELTRPFTSNKTCAKQWVVLAY.SVREALFEAAKELLRQHCDYAHMTLRPDARG.PIVLLLLSFRAQKNRDTVHKLLQGMLNVNTLHLLSNPPRMRSVVVGLFWYRLSLSNMTTVFGPTPDWLKRLTLLQHQ.CEEAMKFEFSDMVQWAYDNHVTEESQIAYGYASLADTNANAAAFLACASQAKYVR.DVATMVK..Y..YRRAEM..QNMSISEWIHRQAERI...E....GEGDW....RPIINFLK.H....Q....GVE....ISVFINNLKH.F.V..K.G..V.P.KK.NCMVLVGPPNTGKSSFAVSLL.E.F..M..N..GKVLFF...PN.S..KSHF..WLMPL..ADT..RMA.....LLDDATGPVWDFF.DHYMRNAMDGNPISVDQKHKQP.LQLR...CPPL.LMTTNVD.......IS..Q....E...SK.....Y.....WYLHSRMIVLRFPNPF.PLDENQQPVFELTVKNWKSLFKRLWQRLELSDQEDEG..D..DGEPTQGFRC..................................................
U6HHE5_ECHMU/45-217                  ..................................................................ypknhsgpsrkesiqwledmf--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....-------S.A....N....AIA....VVDFAITLRI.I.M..N.C..EdE.KI.NTLVLYGPTNTGKSLICKLMT.S.F..L..E..HGSVMR...RQ.E..ASAF..AYENL..LNR..KVA.....LMEEPKICAAN--.QQDLKQILGGEPFEVHTKYQNP.DLLE...RLPV.VVTTNEP.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------lgvrlsdvdaaategrckiytldkqicnan....................
VE1_CRPVK/162-593                    ......................................................................................l-FRQAHSVSFSELTRTFQSDKTMSWDWVGGLA.DIHVSVLESLQTSLRSHCVYVQYDLNFAETNaSSLLLLLRFKAQKCRDGVKALLSQLLGVQDLKVLLEPPKTRSVAVALFWYKRAMVSGVFSYGPMPEWITQQTNVNHQ.MLQEKPFQLSVMVQWAYDNHLQDESSIAYKYAMLAETDENARAFLASNSQAKYVR.DCCNMVR..L..YLRAEM..RQMTMSAWINYRLDGM...N....DDGDW....KVVVHFLR.H....Q....RVE....FIPFMVKLKA.F.L..R.G..T.P.KK.NCMVFYGPPNSGKSYFCMSLI.R.L..L..A..GRVLSF...AN.S..RSHF..WLQPL..ADA..KLA.....LVDDATSACWDFI.DTYLRNALDGNPISVDLKHKAP.IEIK...CPPL.LITTNVD.......VK..S....D...DR.....W.....RYLFSRICVFNFLQEL.PIR-NGTPVYELNDANWKSFFKRFWSTLELSDPEDEG..D..DGGSQPALRL..................................................
VE1_BPV3/174-604                     ......................................................................................i-FKEKFGISLNSLTRIFKNDKTCCSNWVGVVF.GAREELLAASQTILQRVCDSIMLLTHTCKLG.FMGLYLLEFKNAKSRDTVRHLFQQILQVENNDMLLEPPKIKSLPAATFWWKLRHSSAAFLFGNLPDWIARQTSITHQ.IQEDQPFDLSAMVQWAYDHNFVDEAQIAYYYARLASEDSNAAAFLRCNNQVKHVK.ECAQMTR..Y..YKTAEM..REMSMSKWIKKCLNEI...E....GTGDW....KQIINFIK.Y....Q....NIN....FLSFLACFRD.L.L..H.S..V.P.KR.NCLVIVGPPNTGKSMFVMSLM.R.T..L..K..GRVLSF...VN.S..KSHF..WLQPL..NAA..KIA.....ILDDATRPTWSYI.DTYLRNGLDGTPVSLDMKHRAP.MQIC...FPPL.IITTNVD.......VA..K....D...PT.....F.....VYLHSRLMSFEFANAF.PLDENGKPALILNELSWKSFFERLWNQLDLTEPEDED..-..DGDPPSPFRC..................................................
A0A068XWQ7_ECHMU/72-255              .....................................................................knhsgpsrkesiqwledm--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....------FS.A....N....EIA....VVDFAITLRI.I.M..N.C..EdE.KI.NTLVLYGPTNTGKSLICRLTT.S.F..L..E..HGSVMR...RQ.E..ASAF..AYENL..LNR..KVA.....LMEEPKICAAN--.QQDLKQILGGEPFEVHIKYQNP.DLLE...RLPV.IVTTNEP.......L-..-....-...--.....-.....----------------.-------------------------------------..-..----------gvrlsdvdaaaiegrckiytldkqicnanidgsvpappyklc........
G3BER3_CANTC/1-57                    ......................................................................................m--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....--------.-....-....---....-FRYLRFLKN.S.I..M.T..T.P.KK.SVVAIVGTTGVGKSKFSIDLA.H.A..I..N..GEIIN-...--.-..----..-----..---..---.....-------------.----------------------.----...----.-------.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------adsmqvykk.........................................
Q6BLT1_DEBHA/1-56                    ......................................................................................m--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....--------.-....-....---....IIRYLRYFKN.L.M..M.T..T.P.KK.NIVTIVGTTGVGKSQFSIELA.K.A..I..N..GEIIN-...--.-..----..-----..---..---.....-------------.----------------------.----...----.-------.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------adsmqvy...........................................
VE1_PAPVE/170-602                    ......................................................................................l-FKTLYIAGFGEITRVFQSDKTNNNQWVIAAH.GASEVLYAASFEILSKHCSYLQASRKVHETG.SMSLFLAVFNVGKSRETVRKLISGVLNTPCSRLLLQPPKIRGLCPALFWFKLGLSPATQTHGTTPDWIKQQTNVAYN.TGEASKFDFGTMVQWAYDHRLTEECKIAYQYAKCAGTDLNAKAFLASTNQARLVK.DCCTMVK..H..YLRAEE..QSLTISAFIKRRCDNA...T....GKGSW....LSIMNLLK.F....Q....GIE....PINFVNALKP.W.L..K.G..T.P.KH.NCIAIVGPPNSGKSLLCNTLM.S.F..L..G..GKVLTF...AN.H..SSHF..WLAPL..TDC..RVA.....LIDDATHACWRYF.DTYLRNVLDGYPVCIDRKHKSA.VQLK...APPL.LLTSNID.......VH..A....D...EK.....Y.....FYLQSRVKTFYFKEPC.PASDTGEPLFFITDADWKNFFERLWERLDLSDQEDEV..D.eDECSQRSFTC..................................................
B7P8E5_IXOSC/1-170                   ....................................................................................mdv--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-SASY....DAMVRLLE.Y....Q...lGEE....VQEFVHDLYN.L.L.eR.R..V.P.KK.NCMEVVSPPSAGKNFFFDAVV.S.F..YinR..GNIHNF...-N.R..YSNF..PLQDA..VGK..RVL.....IWNEPNCESAAY-.-ETIKKIFGGDVDNVAVKYSPD.MIVT...RTPV.IVLSNNE......tFP..R....D...EA.....F.....N---------------.-------------------------------------..-..----------hrmfrykwrscpalkqydkkihp...........................
Q5UUY3_9PAPI/173-602                 .......................................................................................KFKDTYGISFTELTRPFKSDKTCCEDWVAALY.GISGPLYEGAKQLLEGHVIYMQLTLGTTANG.LLLLMLLRLKHAKSRATLRRLLQNIFNISEMQLLAEPPKTRSVPVALFWYKGTLSSLSYNFGTCPEWIHRQTLINHQ.SMDELKFDLSSMIQWAYDYDYDDECTIAYQYARLAETDANANAWLNSPAQARYVK.DTATMVK..Y..YKRAQM..REMTMGEWIKHRLEKI...D....EEGDW....KKIVQFIR.F....Q....GIE....FPLFFGALKK.F.L..H.G..I.P.KH.NCIVIWGPPDTGKSMFCMNLI.K.L..L..G..GKIISF...AN.S..KSQF..WLQPL..ADA..KVG.....LLDDATGVCWDYI.DQYLRNALDGNPISIDLKHRAP.TQMK...CPPL.LITTNLD.......IT..A....N...SR.....W.....RYLVSRVACFKFSEPF.PFTDRDTPTYPLTECNWKALLERLWKQLDFPEQEEE-..-..DGSTTRPFKC..................................................
G7YUC3_CLOSI/298-418                 ................................................................srfedhirtnshnrdcqhprdtl--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....DGEHW....LDLLLFV-.-....N....RIN....KQQFLADLTR.V.M.nK.E..V.D.RK.NAFVLEGPTTTGKTLFVKLIAdS.Y..I..Y..GTV-QR...SG.D..HSQF..FLMNL..LNK..ALA.....LMEE---------.----------------------.----...----.-------.......--..-....-...--.....-.....----------------.-------------------------------------..-..----------pritqltvnd........................................
E0SH87_DICD3/267-473                 ...................................................fwkwlsrsvgnnkrkadrvlaalfmvlanrydwqlf--------------------------------.-------------------------------.-----------------------------------------------------------------------------.-------------------------------------------------------.-------..-..------..----------------...-....-----....--------.-....-....---....----------.-.-..-.-..-.-.--.--LEVTGPGGSGKSVFAE-IC.T.M..L..A..GKANT-...VS.A..SMKA..LEDPR..DRA..LVVgysliIMPDMTRYAGD--.GAGIKAITGGDKVSIDPKHKAP.YSTR...IPAV.VLAVNNN.......AM..T...fS...DR.....S.....GGISRRRVIFNFSEVV.PENER-DP-----------------------------..-..----------mlaekiegelaviirhlltrfakqdeakrllheqqkseeama........
#=GC seq_cons                        ........................................................................................FKt.hshsh.-lsR.apSs+o.s.pWVh.hh.th...h.ts....l...s.ah.h.......t....hhhhta.s.KsRtsl.phhtth.......hh.pPPph+s..sAhaa.+......s..hG.hPpWh.p.h.htt....t...Fphs.MlQWAhDpth.p-s.lAa.YA.hut.s.NA.taLtpssQs+hV+.-ss.Ms+..h..Yhpt.h..tthshttal..phpth...t.....tspW....p.Ih.aL+.a....Q....slp....hlsFhtsL+t.h.L..p.s..h.P.K+.NClVlhGPsNTGKShFshuLh.p.F..L..p..Gplloa...sN.p..pSpF..WLpPL..hss..Klu.....LlDDsThssWsah.DphlRshLDGsslslDhKH+sP.hQl+...pPPl.llToN.s.......l...t....p...pp.....a.....hYL.oRh.hh.F.p.h.Pht.tspP.h.hp..pWpshh.+h..pLtlt.......................................................................
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