GenomeNet

Database: Pfam
Entry: PepSY_2
LinkDB: PepSY_2
Original site: PepSY_2 
#=GF ID   PepSY_2
#=GF AC   PF13670.5
#=GF DE   Peptidase propeptide and YPEB domain
#=GF AU   Coggill P
#=GF SE   Jackhmmer:C6QGP5
#=GF GA   24.30 24.30;
#=GF TC   24.30 24.30;
#=GF NC   24.20 24.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   7674922
#=GF RT   Evolutionary families of metallopeptidases. 
#=GF RA   Rawlings ND, Barrett AJ; 
#=GF RL   Meth Enzymol 1995;248:183-228.
#=GF RN   [2]
#=GF RM   15124630
#=GF RT   The PepSY domain: a regulator of peptidase activity in the
#=GF RT   microbial environment?. 
#=GF RA   Yeats C, Rawlings ND, Bateman A; 
#=GF RL   Trends Biochem Sci 2004;29:169-172.
#=GF RN   [3]
#=GF RM   15583150
#=GF RT   Identification of residues in the Pseudomonas aeruginosa
#=GF RT   elastase propeptide required for chaperone and secretion
#=GF RT   activities. 
#=GF RA   McIver KS, Kessler E, Ohman DE; 
#=GF RL   Microbiology 2004;150:3969-3977.
#=GF DR   INTERPRO; IPR025711;
#=GF DR   PROSITE; PDOC00129;
#=GF DC   This Prosite motif covers only the active site.
#=GF DR   MEROPS; M4;
#=GF DC   This is family M4 in the peptidase classification. 
#=GF DR   SCOP; 1qf2; fa;
#=GF CC   This region is likely to have a protease inhibitory function
#=GF CC   (personal obs:C Yeats).  The name is derived from Peptidase &
#=GF CC   Bacillus subtilis YPEB.
#=GF SQ   763
#=GS Q5NXN5_AROAE/7-97         AC Q5NXN5.1
#=GS H0JB62_9PSED/5-84         AC H0JB62.1
#=GS A0A0F2P656_9RHIZ/5-86     AC A0A0F2P656.1
#=GS A0A0J1H9S2_9GAMM/5-88     AC A0A0J1H9S2.1
#=GS I4MT27_9BURK/5-87         AC I4MT27.1
#=GS A0A0Q4Y0E6_9RHIZ/5-85     AC A0A0Q4Y0E6.1
#=GS A0A069PFG7_9BURK/5-84     AC A0A069PFG7.1
#=GS I4W6Z5_9GAMM/5-106        AC I4W6Z5.1
#=GS A0A0F4R2V7_9GAMM/6-83     AC A0A0F4R2V7.1
#=GS Q1LC76_CUPMC/10-98        AC Q1LC76.1
#=GS A0A0D6S1D2_9PSED/1-84     AC A0A0D6S1D2.1
#=GS F2BEJ7_9NEIS/3-91         AC F2BEJ7.1
#=GS A0A101JY25_9BRAD/5-97     AC A0A101JY25.1
#=GS A0A0L0MFN1_9BURK/3-85     AC A0A0L0MFN1.1
#=GS I4W0Q4_9GAMM/6-88         AC I4W0Q4.1
#=GS G7UVJ2_PSEUP/80-142       AC G7UVJ2.1
#=GS W0SGX5_9RHOO/9-96         AC W0SGX5.1
#=GS A0A0Q7A6G1_9BURK/3-86     AC A0A0Q7A6G1.1
#=GS A0A0M9EGB7_9RHOB/3-85     AC A0A0M9EGB7.1
#=GS A0A0P0ACD9_9RHOB/5-87     AC A0A0P0ACD9.1
#=GS A0A0F3IPB2_9PROT/1-85     AC A0A0F3IPB2.1
#=GS A0A0W1A1N3_9GAMM/9-86     AC A0A0W1A1N3.1
#=GS A3X8K5_9RHOB/6-80         AC A3X8K5.1
#=GS A0A126RLN3_9SPHN/1-84     AC A0A126RLN3.1
#=GS A0A098GBJ1_TATMI/4-82     AC A0A098GBJ1.1
#=GS Q20WN0_RHOPB/4-89         AC Q20WN0.1
#=GS A0A127F8E6_9GAMM/12-101   AC A0A127F8E6.1
#=GS X7E7R8_9RHOB/4-83         AC X7E7R8.1
#=GS W9H439_9PROT/6-91         AC W9H439.1
#=GS A0A0D6JGH3_9RHIZ/4-88     AC A0A0D6JGH3.1
#=GS J0R650_9RHIZ/8-89         AC J0R650.1
#=GS A0A0T5NVJ7_9RHOB/5-87     AC A0A0T5NVJ7.1
#=GS A0A058ZIS2_9RHOB/3-91     AC A0A058ZIS2.1
#=GS A0A023NVG7_9GAMM/5-79     AC A0A023NVG7.1
#=GS B3KLW3_RHIME/3-102        AC B3KLW3.1
#=GS H0TSB4_9BRAD/110-187      AC H0TSB4.1
#=GS A0A0K8NUF7_IDESA/26-124   AC A0A0K8NUF7.1
#=GS G6YHK8_9RHIZ/5-84         AC G6YHK8.1
#=GS A0A117KHK6_9GAMM/5-86     AC A0A117KHK6.1
#=GS A0A142WUA4_9PLAN/78-146   AC A0A142WUA4.1
#=GS G4CSM4_9NEIS/3-91         AC G4CSM4.1
#=GS L2F8K8_9GAMM/8-105        AC L2F8K8.1
#=GS A0A098TEI9_9RHIZ/1-80     AC A0A098TEI9.1
#=GS S6ANX7_PSERE/15-98        AC S6ANX7.1
#=GS A0A0S2DYC6_9GAMM/81-142   AC A0A0S2DYC6.1
#=GS A0A160MYV6_9GAMM/76-142   AC A0A160MYV6.1
#=GS I1AZ58_9RHOB/5-86         AC I1AZ58.1
#=GS W7WVW1_9BURK/9-90         AC W7WVW1.1
#=GS A0A066UJM8_9GAMM/7-98     AC A0A066UJM8.1
#=GS Q5P446_AROAE/5-88         AC Q5P446.1
#=GS Q3ST17_NITWN/3-83         AC Q3ST17.1
#=GS Q2YQC0_BRUA2/8-90         AC Q2YQC0.1
#=GS A4XVH9_PSEMY/6-85         AC A4XVH9.1
#=GS G9ZUL1_9PROT/85-151       AC G9ZUL1.1
#=GS A0A0R0BJF7_9GAMM/3-79     AC A0A0R0BJF7.1
#=GS A0A0N0K208_9SPHN/3-86     AC A0A0N0K208.1
#=GS A0A0D2WL24_9PROT/13-99    AC A0A0D2WL24.1
#=GS A0A101JXX9_9BRAD/4-95     AC A0A101JXX9.1
#=GS A0A101JAH2_9ACTN/98-167   AC A0A101JAH2.1
#=GS A0A0Q6B9N1_9PROT/6-88     AC A0A0Q6B9N1.1
#=GS F2J3H8_POLGS/5-86         AC F2J3H8.1
#=GS X6D4Z3_9RHIZ/4-84         AC X6D4Z3.1
#=GS C8RZP8_9RHOB/4-87         AC C8RZP8.1
#=GS I9P5T4_9ALTE/3-92         AC I9P5T4.1
#=GS A0A0N8GEN0_9RHIZ/7-89     AC A0A0N8GEN0.1
#=GS A0A166I4V8_9MICO/23-112   AC A0A166I4V8.1
#=GS B9K2Y3_AGRVS/3-85         AC B9K2Y3.1
#=GS A0A0P1GG75_9RHOB/2-83     AC A0A0P1GG75.1
#=GS A0A127FE66_9GAMM/1-81     AC A0A127FE66.1
#=GS A0A085FQN2_9BRAD/6-89     AC A0A085FQN2.1
#=GS K6XJZ6_9ALTE/1-74         AC K6XJZ6.1
#=GS A0A0A2WEF9_9GAMM/84-145   AC A0A0A2WEF9.1
#=GS A0A0F2RNL7_9RHOB/5-86     AC A0A0F2RNL7.1
#=GS G7UVJ2_PSEUP/3-83         AC G7UVJ2.1
#=GS A7IQ64_XANP2/11-92        AC A7IQ64.1
#=GS A0A0R0CT89_9GAMM/78-140   AC A0A0R0CT89.1
#=GS A0A0Q6CUK5_9RHIZ/7-88     AC A0A0Q6CUK5.1
#=GS A0A120HK02_9PSED/8-87     AC A0A120HK02.1
#=GS A0A011UXL3_9RHIZ/4-87     AC A0A011UXL3.1
#=GS A0A0Q5NNR1_9BURK/7-84     AC A0A0Q5NNR1.1
#=GS A0A089ZQH8_9PSED/6-86     AC A0A089ZQH8.1
#=GS A0A0F4PWY3_9GAMM/1-79     AC A0A0F4PWY3.1
#=GS I3THR8_TISMK/248-313      AC I3THR8.1
#=GS A0A165P4L8_9SPHN/11-93    AC A0A165P4L8.1
#=GS A4VHV2_PSEU5/30-109       AC A4VHV2.1
#=GS A0A0X8GPG2_9BURK/2-87     AC A0A0X8GPG2.1
#=GS E3HZP9_RHOVT/11-105       AC E3HZP9.1
#=GS A0A085TX41_9RHOB/6-81     AC A0A085TX41.1
#=GS D0D123_9RHOB/5-83         AC D0D123.1
#=GS B8EKV5_METSB/3-81         AC B8EKV5.1
#=GS A0A109BPF3_9BURK/7-88     AC A0A109BPF3.1
#=GS A0A0B4XDT9_9RHIZ/3-104    AC A0A0B4XDT9.1
#=GS A0A0R0DQE7_9GAMM/84-142   AC A0A0R0DQE7.1
#=GS A0A0Q6VMM2_9BURK/7-90     AC A0A0Q6VMM2.1
#=GS I3I5N5_9GAMM/2-85         AC I3I5N5.1
#=GS B5GL13_STRC2/97-167       AC B5GL13.1
#=GS V4QW66_9RHIZ/1-83         AC V4QW66.1
#=GS D5RR60_9PROT/16-96        AC D5RR60.1
#=GS A0A0B3SM43_9RHOB/3-83     AC A0A0B3SM43.1
#=GS L0NB92_9RHIZ/3-85         AC L0NB92.1
#=GS A0A0Q3I6D7_9BRAD/3-96     AC A0A0Q3I6D7.1
#=GS Q2YJ59_BRUA2/1-46         AC Q2YJ59.1
#=GS W9HDC9_9PROT/7-91         AC W9HDC9.1
#=GS A0A0Q8NNJ0_9RHIZ/4-100    AC A0A0Q8NNJ0.1
#=GS Q2W5D9_MAGSA/5-85         AC Q2W5D9.1
#=GS H0Q2Y2_9RHOO/5-88         AC H0Q2Y2.1
#=GS A0A0Q8RAP5_9SPHN/1-79     AC A0A0Q8RAP5.1
#=GS A0A177QYA2_9PROT/2-84     AC A0A177QYA2.1
#=GS F1W0R5_9BURK/9-91         AC F1W0R5.1
#=GS A1B772_PARDP/5-86         AC A1B772.1
#=GS A0A0Q4XNS3_9RHIZ/5-83     AC A0A0Q4XNS3.1
#=GS B2FKQ4_STRMK/2-78         AC B2FKQ4.1
#=GS H8FVM2_PHAMO/7-96         AC H8FVM2.1
#=GS A0A142HK99_9BACT/4-76     AC A0A142HK99.1
#=GS I4W100_9GAMM/104-165      AC I4W100.1
#=GS A0A0Q7PPN5_9GAMM/77-138   AC A0A0Q7PPN5.1
#=GS A0A0U3BA31_9ALTE/6-83     AC A0A0U3BA31.1
#=GS Q5P431_AROAE/5-88         AC Q5P431.1
#=GS A0A063B4P2_9BURK/8-92     AC A0A063B4P2.1
#=GS A0A0C1YSA0_9BURK/3-85     AC A0A0C1YSA0.1
#=GS A0A085TUA5_9RHOB/5-86     AC A0A085TUA5.1
#=GS A0A126P422_9BRAD/2-99     AC A0A126P422.1
#=GS S6KFR4_9PSED/6-87         AC S6KFR4.1
#=GS A0A0W0WKG0_9GAMM/4-82     AC A0A0W0WKG0.1
#=GS A0A0R0A8J4_9GAMM/8-91     AC A0A0R0A8J4.1
#=GS A0A0C3HM24_9VIBR/1-66     AC A0A0C3HM24.1
#=GS A0A0F2P4D7_9RHIZ/4-87     AC A0A0F2P4D7.1
#=GS K6ZZY6_9ALTE/10-88        AC K6ZZY6.1
#=GS A5WEP8_PSYWF/56-122       AC A5WEP8.1
#=GS A0A095V5R8_9RHIZ/5-86     AC A0A095V5R8.1
#=GS Q4K9Y2_PSEF5/25-108       AC Q4K9Y2.1
#=GS A0A0D1M2H0_BRAEL/6-90     AC A0A0D1M2H0.1
#=GS A0A0P1GFT0_9RHOB/9-91     AC A0A0P1GFT0.1
#=GS A0A0P1FL99_THAGE/7-84     AC A0A0P1FL99.1
#=GS Q6MRI8_BDEBA/3-85         AC Q6MRI8.1
#=GS A0A0Q9EC91_9RHIZ/27-106   AC A0A0Q9EC91.1
#=GS A0A0D7EZ49_RHOPL/4-89     AC A0A0D7EZ49.1
#=GS H1S6X0_9BURK/3-85         AC H1S6X0.1
#=GS A0A0Q9PE60_9GAMM/4-79     AC A0A0Q9PE60.1
#=GS Q3SV66_NITWN/5-83         AC Q3SV66.1
#=GS D5AQE8_RHOCB/8-90         AC D5AQE8.1
#=GS A0A0Q4XV74_9RHIZ/6-85     AC A0A0Q4XV74.1
#=GS A0A0J5GH54_9NEIS/4-86     AC A0A0J5GH54.1
#=GS A0A078LTM6_9PSED/6-85     AC A0A078LTM6.1
#=GS Q1QM53_NITHX/9-102        AC Q1QM53.1
#=GS J1TCU9_9RHIZ/3-87         AC J1TCU9.1
#=GS A0A0F7JRE7_9GAMM/8-96     AC A0A0F7JRE7.1
#=GS A7IKT6_XANP2/6-87         AC A7IKT6.1
#=GS A0A0D1LRK3_BRAEL/3-83     AC A0A0D1LRK3.1
#=GS A0A0M6ZA02_9RHOB/6-89     AC A0A0M6ZA02.1
#=GS A0A0Q4GW68_9BURK/8-95     AC A0A0Q4GW68.1
#=GS A0A150WPN2_BDEBC/2-85     AC A0A150WPN2.1
#=GS A0A089Y8F8_9PSED/2-85     AC A0A089Y8F8.1
#=GS Q1ZWJ2_PHOAS/5-89         AC Q1ZWJ2.1
#=GS A0A172YH88_9GAMM/87-155   AC A0A172YH88.1
#=GS A0A0D0R4C4_9GAMM/4-87     AC A0A0D0R4C4.1
#=GS A0A0Q7U3I6_9RHIZ/5-91     AC A0A0Q7U3I6.1
#=GS C3K1S1_PSEFS/2-85         AC C3K1S1.1
#=GS A0A0J6R8A5_9RHIZ/58-126   AC A0A0J6R8A5.1
#=GS A0A139DCV9_9ALTE/3-84     AC A0A139DCV9.1
#=GS A0A160FNR3_9BURK/3-87     AC A0A160FNR3.1
#=GS A3KB53_9RHOB/3-86         AC A3KB53.1
#=GS A0A0Q3BPX4_9RHOB/4-86     AC A0A0Q3BPX4.1
#=GS B9QWG8_LABAD/19-97        AC B9QWG8.1
#=GS A0A0T6LTH5_9ACTN/70-135   AC A0A0T6LTH5.1
#=GS V5SAS1_9RHIZ/3-88         AC V5SAS1.1
#=GS D0J2B8_COMT2/28-123       AC D0J2B8.1
#=GS A0A0Q5MRE4_9MICO/38-123   AC A0A0Q5MRE4.1
#=GS F7SW42_9BURK/8-110        AC F7SW42.1
#=GS A0A0M2VFD6_9GAMM/6-84     AC A0A0M2VFD6.1
#=GS A0A0Q9HKZ8_9BRAD/9-92     AC A0A0Q9HKZ8.1
#=GS A0A090F500_9RHIZ/170-251  AC A0A090F500.1
#=GS A0A0M9X985_9ACTN/139-207  AC A0A0M9X985.1
#=GS A0A069PH25_9BURK/3-85     AC A0A069PH25.1
#=GS Q5F6R1_NEIG1/3-91         AC Q5F6R1.1
#=GS Q5P432_AROAE/18-101       AC Q5P432.1
#=GS H4F662_9RHIZ/4-87         AC H4F662.1
#=GS A0A0B8WGG6_9DELT/4-86     AC A0A0B8WGG6.1
#=GS A0A0Q7PJT1_9RHIZ/31-106   AC A0A0Q7PJT1.1
#=GS A3JXM1_9RHOB/4-83         AC A3JXM1.1
#=GS F6A9Z6_PSEF1/6-85         AC F6A9Z6.1
#=GS A0A081G2W3_9GAMM/5-87     AC A0A081G2W3.1
#=GS L1P3G3_9NEIS/3-101        AC L1P3G3.1
#=GS A7IQ54_XANP2/6-90         AC A7IQ54.1
#=GS B2FKQ5_STRMK/2-93         AC B2FKQ5.1
#=GS Q9K0U4_NEIMB/3-91         AC Q9K0U4.1
#=GS H4EZK1_9RHIZ/4-85         AC H4EZK1.1
#=GS D4XI21_9BURK/8-99         AC D4XI21.1
#=GS A0A0W0VS72_9GAMM/82-145   AC A0A0W0VS72.1
#=GS L8EQT1_STRRM/137-205      AC L8EQT1.1
#=GS Q3J2H8_RHOS4/3-84         AC Q3J2H8.1
#=GS A0A0A0EQ65_9GAMM/3-81     AC A0A0A0EQ65.1
#=GS A0A0Q8QKC3_9SPHN/4-85     AC A0A0Q8QKC3.1
#=GS M1FJV1_9ALTE/5-86         AC M1FJV1.1
#=GS F9EZ94_9NEIS/6-87         AC F9EZ94.1
#=GS V4PA59_9CAUL/5-90         AC V4PA59.1
#=GS A0A0H1A310_9RHIZ/3-80     AC A0A0H1A310.1
#=GS A0A163CY51_9NEIS/5-87     AC A0A163CY51.1
#=GS A0A0Q7XIL3_9RHIZ/4-85     AC A0A0Q7XIL3.1
#=GS A0A0P6VQA4_9RHIZ/5-86     AC A0A0P6VQA4.1
#=GS A0A098T1D8_9PSED/5-86     AC A0A098T1D8.1
#=GS G7ZF59_AZOL4/5-94         AC G7ZF59.1
#=GS Q1QQG0_NITHX/5-83         AC Q1QQG0.1
#=GS A0A160DS83_9GAMM/85-150   AC A0A160DS83.1
#=GS A0A0R0D7T7_9GAMM/5-95     AC A0A0R0D7T7.1
#=GS A0A160DS83_9GAMM/149-214  AC A0A160DS83.1
#=GS A0A0Q6EDL3_9RHIZ/6-82     AC A0A0Q6EDL3.1
#=GS F3KE31_9GAMM/5-88         AC F3KE31.1
#=GS A1VTH7_POLNA/3-85         AC A1VTH7.1
#=GS A0A0Q7MJA6_9RHIZ/4-106    AC A0A0Q7MJA6.1
#=GS A0A0M6XTD7_9RHOB/5-86     AC A0A0M6XTD7.1
#=GS K0UM96_MYCVA/6-63         AC K0UM96.1
#=GS Q0BXA6_HYPNA/7-95         AC Q0BXA6.1
#=GS I4W6Z5_9GAMM/104-165      AC I4W6Z5.1
#=GS V9H9K8_9NEIS/9-101        AC V9H9K8.1
#=GS A0A0K1NCH7_9BURK/149-215  AC A0A0K1NCH7.1
#=GS A0A059KLN1_9BURK/7-89     AC A0A059KLN1.1
#=GS N6Y906_9RHOO/3-96         AC N6Y906.1
#=GS A0A127CF68_9RHIZ/3-82     AC A0A127CF68.1
#=GS A0A101D4I0_9GAMM/96-156   AC A0A101D4I0.1
#=GS A0A165U7M8_9GAMM/9-87     AC A0A165U7M8.1
#=GS W0H255_PSECI/2-85         AC W0H255.1
#=GS A0A0Q5ZKP3_9RHIZ/5-85     AC A0A0Q5ZKP3.1
#=GS A0A0A1VGM8_9BURK/19-111   AC A0A0A1VGM8.1
#=GS A0A101K1B7_9BRAD/3-87     AC A0A101K1B7.1
#=GS A0A014QDT4_9BURK/38-121   AC A0A014QDT4.1
#=GS A0A162CVH7_9SYNE/6-79     AC A0A162CVH7.1
#=GS A7HVA0_PARL1/5-87         AC A7HVA0.1
#=GS W6W430_9RHIZ/2-105        AC W6W430.1
#=GS A0A0Q9I3E2_9BRAD/4-96     AC A0A0Q9I3E2.1
#=GS Q0FUG9_PELBH/5-86         AC Q0FUG9.1
#=GS A0A0R0E2N4_9GAMM/82-142   AC A0A0R0E2N4.1
#=GS G2J097_PSEUL/4-86         AC G2J097.1
#=GS A0A085TRL2_9RHOB/5-86     AC A0A085TRL2.1
#=GS A0A0P0ADL8_9RHOB/5-86     AC A0A0P0ADL8.1
#=GS Q885E0_PSESM/2-85         AC Q885E0.1
#=GS C5T4R9_ACIDE/9-90         AC C5T4R9.1
#=GS M7P3T3_9GAMM/88-152       AC M7P3T3.1
#=GS A0A0Q8NLZ2_9RHIZ/4-99     AC A0A0Q8NLZ2.1
#=GS Q1Z0D6_9GAMM/8-91         AC Q1Z0D6.1
#=GS A0A135HR46_9RHIZ/3-89     AC A0A135HR46.1
#=GS A0A098T6N8_9RHIZ/5-86     AC A0A098T6N8.1
#=GS A0A0K0TZ47_9RHIZ/4-85     AC A0A0K0TZ47.1
#=GS A1B655_PARDP/3-84         AC A1B655.1
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X6FN94_9RHIZ/10-92                   .........................................tvlh----VAALV.IAS.....tFSALA....................-AD..AC....D..V.....P.V......VDWQ..............PRETL....K.S.....Q.LE....S....AG.W..S...V..T....SIT..A..K....S.G-C......YEAT...G....TD..N....A..GH.....VV..VATFNPQTLAPVGQ-q.............
K2JDJ0_9PROT/1-62                    ............................................m---------.---......-----....................---..--....-..Q.....P.P......ADAM..............PLSQI....V.A.....K.IE....Q...rPD.F.rY...I..D....DLE..W..D....D.DGY......YEIE...Y....RT..K....E..GG.....EV..RLKLDPKTGE-----arr...........
A1TTN9_ACIAC/142-208                 .................................gqaggtlngqpv---------.---......-----....................---..--....-..-.....-.-......---L..............SADQV....R.Q.....A.LQ....V....AG.Y.tR...I..R....DID..Y..D....D.G-F......WEAE...A....TN..A....A..NL.....PV..ELRVEPTTGKVLREK..............
A1W3D6_ACISJ/6-89                    ...........................................ph--IAALALA.VSA......SSAFAh..................gKVT..CP....E..H.....P.P......AEWR..............PHTEL....E.Q.....K.LV....K....EG.W..T...V..R....RME..K..T....E.T-C......YEVY...G....KD..P....Q..GK.....RV..EAFFDPKTLERVQ--d.............
I4WQV9_9GAMM/5-85                    .....................................lapltlal--ALATPVL.VLP......-----....................---..-T....A..A.....A.A......QQAM..............TEPQV....Q.S.....Q.LT....A....QG.Y.tK...V..H....DLK..F..R....D.G-M......WYAE...A....RS..A....N..GS.....RV..DLRIDAGTGQVY---pde...........
A6X6Z4_OCHA4/6-101                   ..........................................rnl---AGAAFL.LLA......PAAFAqttpteepq..tpavttpgeKNP..KA....P..V.....P.G......QNSF..............TEDQA....K.E.....R.LT....E....EG.F.sN...I..M....NLQ..L..G....E.DGI......WRAE...-....AA..R....D..GQ.....PV..KVLLD----------fqgn..........
A0A0B5CKA0_NEIEG/3-91                ............................................k-FLITAVIA.LSA......ASASAn.................dyIEH..QI....Y..S.....D.K......NFEQ..............NRAKA....V.R.....M.LE....Q....RG.Y..Q...V..H....EID..P..D....D.HWGk...pvLEIE...-....AY..K....N..GR.....EY..DIILSYPDLKIIRE-t.............
A0A0T5NVK3_9RHOB/5-86                ............................................l-TIIGFLAV.FPV......GAALA....................-DD..DC....F..V.....P.M......ADWQ..............PRDAV....A.M.....L.AE....E....NG.W..T...V..R....RIK..I..D....D.G-C......YEID...G....RD..A....E..GR.....AI..EVTVHPATLEIIE--fe............
S9RWX1_9RHOB/6-82                    .........................................tapl----LALTL.TFG......AAGIA....................---..-Q....A..S.....P.D......IDSA..............RQDEI....R.T.....R.LA....E....QG.Y..E...V..R....KID..A..E....D.G-M......IEVY...-....AL..K....D..GQ.....RF..ELYLDDQ-LEIVR--tk............
A0A0D5V3R4_9BURK/7-89                ...........................................rl--AAAVALI.ALP......FAAHA....................TGS..CT....T..E.....P.K......TKWM..............QDKEV....S.S.....Q.LE....K....QG.Y..Q...V..K....RVK..T..-....E.GSC......YEVY...A....LD..K....K..GN.....HH..EMVVNPVDGKPVSEE..............
A0A0D5M406_9GAMM/7-90                ...........................................ki--ITSALLL.TAS......TAALA....................ETH..CT....D..A.....P.S......DEWI..............SQADM....E.E.....R.IS....E....MG.Y..K...I..K....EFK..V..T....E.GNC......YEIY...G....WD..E....Q..ER.....RV..EIYFNPVDASIVKQE..............
W9E4N7_RHILI/5-84                    ............................................l-VATSVAVF.LAA......GPALA....................-AD..DK....P..L.....P.P......PNAK..............KLSEI....L.A.....K.VE....Q...rDG.F.rY...V..K....EVD..W..D....N.G-A......YTVT...Y....YT..S....D..KA.....KV..EITYDPVTAE-----p.............
W8R1I2_PSEST/6-86                    ...........................................lt--AALAIAV.LGSa....sTVALA....................---..--....D..R.....P.G......TGWI..............SLEQA....V.E.....K.AK....A....AG.Y.tQ...L..Y....SIE..A..D....D.D-S......WEGE...G....TK..Q....D..GK.....TY..EFRIDGKTGEVTRD-r.............
A0A0N1B351_9BRAD/9-94                ...........................................al--LLSALLA.LPAt....vVNAQA....................PSP..AP....I..R.....P.G......QTAI..............SMDDA....R.R.....I.AN....D....NG.V.vR...I..E....EIE..L..D....D.G-K......WEIE...G....RD..A....A..GA.....EI..EIDLRATDGMIIKM-e.............
P72639_SYNY3/9-92                    ...................................yflagvvlme-------MT.L--......TAAIA....................-RA..DD....R..D.....V.T......AQE-..............-RQRI....V.Q.....A.LN....A....LG.C.sS...F..D....DAE..Y..E...iD.KRR......FEID..dA....IC..A....D..GR.....KY..EIYLDAN--------yqlikke.......
A0A0N1BTG8_9PROT/7-99                ................................lagllltgslaag----AYAYA.QGA......GTGAA....................-PM..SG....P..S.....M.A......ADTL..............SMPAL....L.D.....K.LS....A....QG.Y.rD...A..R....SVE..R..K....S.DKL......VEVK...A....TG..P....D..GQ.....RQ..ELYVDARTGEILKV-e.............
D7A7P1_STAND/4-86                    ...........................................al-TILACIAV.LPV......GQALA....................-DD..DC....F..A.....P.M......ADWK..............PKEAV....A.A.....L.AT....R....NG.W..T...V..R....RIK..I..D....D.G-C......YEID...G....TD..A....E..GQ.....RI..EVTVHPSTLDVIE--ie............
R4YUS5_OLEAN/5-87                    ............................................r-ITTFIAAC.LLS......SAALA....................DDD..DC....A..G.....S.L......TDWQ..............PKEQL....R.Q.....K.MV....D....KG.W..D...I..K....RIK..V..D....D.G-C......YEVK...G....RD..R....N..GH.....RV..EAKFSPASLELIEL-e.............
A0A136FRK0_9PSED/5-84                ...........................................ll-ASLFACSV.LAS......TAALA....................---..--....D..Q.....P.G......ADWM..............PMNDV....K.S.....K.LM....E....QG.Y.tS...I..T....KIE..A..D....D.G-Q......WEGE...G....MK..K....D..GM.....KY..DFHADAKTGKITKEK..............
A0A0A2SPC0_9GAMM/143-203             ....................................ntqkypisl---------.---......-----....................---..--....-..-.....-.-......----..............--LEA....A.Q.....K.IE....G....AG.Y.hS...I..Y....KIE..S..-....H.GSQ......YEVK...A....LG..K....E..DT.....KV..KLRVDANTGKINRD-e.............
N2J5K1_9PSED/5-84                    ........................................hviag------LLL.SVA......GTGFA....................---..WA....D..Q.....P.G......ADWM..............PKKEV....E.A.....K.II....E....SG.Y.tS...V..S....RLD..A..E....N.G-E......WVGK...G....LK..L....N..SE.....KY..RFRADPRTGNIIQEE..............
I2N6F4_9ACTN/5-95                    .........................................ivia-TAVAALMA.GGT......LTAFAa..................tGSD..DD....R..T.....P.P......AAKV..............TLTEA....T.D.....A.AL....A....KV.P.gT...V..E....SAD..R..D....D.DGKg....dWEID...I....RT..S....E..GT.....ER..EVRVDAQNGSV----rve...........
A0A0Q9YIJ7_9COXI/88-146              .....................................eglallsa---------.---......-----....................---..--....-..-.....-.-......----..............--LEI....A.K.....K.VE....D....AG.Y.rN...I..S....KID..T..-....E.GKE......YEVK...A....LS..K....E..GK.....ET..KLLVNAQSGEIT---vk............
A0A0F3IWJ8_9PROT/5-87                ..........................................lpl---TSLALC.LAS......SLTLA....................SGT..HC....T..A.....P.V......ADWQ..............PRENL....Q.R.....K.LE....N....DG.Y..S...V..H....RIK..V..D....D.G-C......YEVK...A....TD..R....A..GK.....HL..EIKYDPKSFAPLK--ie............
A0A126NUJ9_9BRAD/1-84                ........................................miglg------ALL.AMS......GLAGA...................qAPA..PI....R..P.....D.A......LPAI..............SMDQA....R.R.....I.AA....D....NG.M.mR...V..D....DIK..L..-....D.NGV......WDVD...G....RD..G....T..GA.....EM..ELKVRATDGTVIKV-e.............
A0A011PTN0_9PROT/8-99                .............................paliigvvlgaasafi---------.---......TPAFSdd................krPPA..AA....S..T.....A.D......RQWL..............SIPQI....V.D.....K.LE....A....AG.Y.rN...I..E....EIE..R..E....H.G-K......YEVR...A....TR..R....D..GT.....RS..KLYVHPQTGEVMD--sr............
A0A0S2DNW9_LYSEN/96-158              .......................................ypdeqv---------.---......-----....................---..--....-..-.....-.-......-AQL..............SRRDI....Q.A.....S.LS....A....AG.Y.tD...I..H....DLD..Y..R....D.G-L......WLAK...A....ED..P....G..GR.....DV..ELRLDPDNGRIVG--vd............
A0A117MVU0_9BRAD/4-95                ...................................liitsfvasv---------.-MS......MGAFAqtstts.......paptpapADA..NA....P..L.....P.G......ANSF..............TEGQA....K.S.....R.LE....A....NG.Y.sA...I..S....ELK..K..D....D.NGV......WKGT...-....AT..H....G..GQ.....PV..TVSVDYR--------gni...........
L1NK69_9NEIS/3-91                    ...........................................ks--LFTALIA.LTA......AASFAd.................dhIER..QI....Y..S.....D.R......NFEQ..............NRAKA....V.K.....M.LE....K....RG.Y..Q...V..Q....EVE..A..D....D.RRGk...pvLDID...-....AY..K....N..GR.....KY..DIVLSYPDLRIIKE-r.............
N0B0Q5_9RHIZ/1-77                    ...........................................ms---------.-VA......GAAHAg.................syGKP..CT....T..Q.....P.Q......EKWM..............SIQQL....E.K.....I.VN....D....HG.Y..K...V..A....KSK..I..-....K.GAC......FEVY...A....RD..P....Q..GQ.....RI..ELFLDPVTGN-----pada..........
A0A0Q7WTP4_9RHIZ/5-89                ............................................i-SAAAFALV.LAA......SPALAq..................sAAP..AP....D..V.....P.P......ANGK..............KLSEI....I.A.....K.VE....K...rPD.F.rY...I..S....EVG..W..D....D.G-G......YDVT...Y....YT..T....D..NA.....KV..EMKFDAVSGE-----trs...........
R7XRU7_9ACTN/31-120                  .........................................taia--AGVLVVA.TGAt....tGVAVA...................tGGD..DT....E..G.....P.I......TGDA..............LKQAS....D.A.....A.LE....F....TG.G.gK...V..T....DTE..V..G....D.EES.....yYEVE...V....TL..G....N..GD.....QV..DVQLDKAFQ------vvdsk.........
A0A0R3MHB6_9BRAD/43-117              ...........................................li--TSSIAIL.VLS.....vLPALA....................---..--....D..R.....P.V......TEDE..............-RAKL....V.A.....A.VQ....A....EG.C..T...G..G....KFE..F..D....E.DDQ.....qFEVD..dA....VC..A....D..GK.....KY..DLKFDA---------qmk...........
A0A0U3N7P2_9BURK/5-86                ...........................................lp--IAVLIAL.TAS......GAARA....................-NV..DC....H..R.....A.T......AEWQ..............PREAV....T.A.....R.AT....E....LG.L..T...T..D....SLR..I..D....D.G-C......YEIR...G....RD..A....D..GN.....WV..TLTFEPATLAVLE--lg............
A0A0Q8BAC3_9RHIZ/5-84                ...........................................vs--AAAIATF.LLA......SGAYA....................-QD..TD....R..A.....P.P......PDAK..............KLSEI....V.A.....K.VE....Q...rNG.F.rY...I..G....DIE..W..D....D.G-A......YEVT...Y....YT..V....D..KA.....KV..EIRFDPVTGE-----p.............
C5AT97_METEA/2-84                    .........................................ntlk----TLAAA.TLA......TGLLA....................ASA..HA....D..T.....P.G......KDWM..............PIDQV....L.T.....K.LA....E....AG.Y.gT...V..R....SIE..A..D....D.G-V......WKAK...-....AV..R....D..GR.....SV..KVQLDPQTGAIVEK-t.............
A4Z1B9_BRASO/8-92                    ............................................i-TAVALGAG.LAS.....gSVAFAd..................gYKD..CT....K..L.....D.K......ASWK..............PTADA....E.A.....K.AK....A....AG.Y..E...V..R....QTK..I..-....E.GTC......YEVY...G....-V..K....G..GK.....LF..ELFYSPEDLA-----lkhtk.........
H0JDD9_9PSED/3-85                    ..........................................rll-----LPLL.FAS......PLALA...................aEPQ..CT....Q..A.....D.K......STWQ..............DAEKF....Q.A.....Q.LR....D....QG.Y..E...I..K....KFK..I..T....K.GNC......YEIY...G....FD..K....D..RR.....KV..EIYHDPVSGKAVKSE..............
A0A126NR60_9BRAD/4-98                .............................liiasliatatsfgam---------.---......----Aqtstts.......paptpapADA..NA....P..L.....P.G......ANSF..............TEGQA....K.S.....R.LE....A....NG.Y.tD...V..T....DLK..K..D....D.NGV......WKGM...-....AM..N....A..GA.....KV..SVSVDYR--------gnivkn........
D3F654_CONWI/9-104                   .........................................igvg--AAVALAA.GGT......GVALAv..................sGGG..DD....G..R.....D.G......NDGApv.........paaTATKA....K.D.....A.AL....Kv..tRG.G..T...V..T....DFE..R..D....D.ERGa....tYEVE...I....AK..P....D..GS.....SV..DVRLDEAF-------klvgqp........
A1U059_MARHV/5-86                    ............................................p-IILSLSLL.LLS......GTAVA....................-DD..DC....D..D.....P.V......ASWQ..............PRENL....R.E.....K.LE....A....EG.W..T...V..H....RIK..V..D....D.G-C......YEVR...G....LD..A....D..GV.....RA..EASFAPASLTMMKW-e.............
A0A160FXI0_9BURK/7-89                ...........................................rl--AAAVALI.ALP......FAAHA....................TGS..CT....T..E.....P.K......TKWM..............QDKEV....S.S.....Q.LE....K....QG.Y..Q...V..K....RVK..T..-....E.GSC......YEVY...A....LD..K....K..GN.....HH..EMVVNPVDGKPVSEE..............
I3THR8_TISMK/188-247                 ...................................rpaaeldlrv---------.---......-----....................---..--....-..-.....-.-......----..............----L....G.E.....R.LA....A....GG.Y.tR...I..T....DVD..L..-....D.RRH......ISAE...A....VS..R....D..GL.....QV..ELRIDPRSYEVIRE-r.............
A1TTN9_ACIAC/77-141                  ..................................ksdiggtlpgv---------.---......-----....................---..--....-..-.....-.-......----..............--DQV....T.Q.....R.LR....S....AG.Y.aV...V..Y....DVE..L..D....D.G-F......WEAK...A....RQsvH....Q..GE.....KV..EFVLHPATLEVLS--qv............
A0A0K1J3M2_9RHOO/5-87                ............................................h-FTLAAAAL.LIG......TSAFA....................GPK..CT....A..A.....P.Q......NT-Q..............PVANT....L.R.....T.LV....D....AG.F..K...F..Q....KAK..V..T....K.EDC......YELK...G....TN..T....V..GD.....RV..EIYLNPADGTNVKT-e.............
R4LIM9_9ACTN/45-133                  ............................................p-TAAASPFV.TAS......PSATA....................SPS..AT....T..S.....P.G......RATS.............vPAAAA....K.A.....I.AL....R...iVG.G.gR...V..E....SVE..G..E....I.EHGr...avWDVD...-....VL..R....N..GV.....EH..DIDVDRTTGAVLRH-r.............
Q5ZZ46_LEGPH/10-90                   ...........................................pm---VLFSGL.LVA......TFAMA....................--E..AT....K..A.....E.E......TSTV..............KLSTI....L.Q.....Q.LS....D....QG.Y.kN...I..H....DAE..I..D....D.G-V......LTVE...G....SN..E....Q..GV.....KF..EIHIDPATGKILKK-q.............
X6L3L1_9RHOB/5-86                    ............................................l-TIIGFLAV.FPA......GAVLA....................-DD..DC....F..V.....P.M......ADWQ..............PRDAV....A.R.....L.AE....E....NG.W..A...V..R....RIK..I..D....D.G-C......YEID...G....RD..A....Q..GR.....AI..EVTVHPATLEVIE--fe............
A1SRM1_PSYIN/6-86                    ...........................................lk---IFTVLS.LCS......AVAQA....................-EV..EC....R..D.....P.V......DKWQ..............PQQQL....R.Q.....R.LE....Q....KG.W..Q...V..K....RIK..V..-....D.DNC......YEVK...A....LD..H....Q..GN.....KI..EARFGPAELDILEL-e.............
A6X0N5_OCHA4/2-80                    ...........................................rl--AVTTLFL.GLS.....vAAAYA....................---..--....-..A.....P.P......PEGT..............KLSEI....I.A.....K.IE....Qs..aDT.A..F...I..D....EVD..W..N....D.RGY......YEIE...Y....VT..K....A..GA.....KV..EVKVDPKTGENV---r.............
I4W100_9GAMM/5-106                   ..............tlplliglsvcsvalaqdppvttqsqttttq---------.---......TTTTA....................-ST..WS....T..E.....P.P......AGAL..............SEEAI....K.T.....A.VA....N....AG.Y.kE...V..K....DLE..F..K....D.G-V......WRSE...A....RG..G....N..KQ.....WV..KIAVGPETGRV----yvsd..........
A0A0H5BF57_BLAVI/50-110              ........................................rrfqa---------.---......-----....................---..--....-..-.....-.-......--EL..............PPWEI....E.T.....M.LR....S....MG.Y.tR...I..S....RPR..M..-....A.GSV......YEVN...A....TD..R....R..GW.....RI..ALVVDSESGRILERE..............
Q0FSA2_PELBH/1-77                    ............................................m------LAL.CLA......GPALA....................---..-D....D..H.....M.V......SDEA..............KAKIA....E.I.....M.TD....M....RC.E.vD...P..D....DIE..M..T....D.EGG......YDLD..dV....IC..E....G..TG.....QF..DIELDAEFNEVGRR-a.............
A0A0C1YIY6_9BURK/3-85                ............................................k-ILAVALAL.SLS......GAAFA....................KAD..CA....A..H.....P.K......SEWM..............KESDA....K.A.....K.IE....S....QG.Y..K...I..R....KFK..V..-....D.GNC......YEIY...G....HD..K....D..GK.....KV..EIYYDTKTLDVVKSE..............
N0B0Y1_9RHIZ/4-86                    ......................................ikiaagi----LASSA.FIV......GVAFA....................---..DG....R..P.....P.T......AEET..............--SAI....S.A.....A.LT....K....AG.F.sE...W..G....KIE..F..D....D.G-K......WEVD..dA....IG..A....D..GK.....QY..DVDLSASDFSVIKKE..............
A0A0Q3KJK1_9BRAD/7-93                ....................................flalavacp-------LW.VLP......HPGQA...................qAPG..PS....A..P.....S.Q......QPAV..............SMEQA....R.R.....I.AA....E....NG.V.vR...V..E....EIS..L..E....R.D-E......WKVE...G....RD..S....T..GA.....EI..EIKLRASDGVIIRM-e.............
A0A0H2LV34_VARPD/8-89                ...........................................rs--LALAILV.LAA......QPVRA....................-ED..DC....D..A.....P.S......ETWQ..............PRSAV....H.A.....L.AE....R....NG.W..R...I..D....KLK..I..D....D.G-C......YEIK...G....RD..A....D..DR.....RF..KAKLDPATLKVVRM-k.............
A0A0F5L0A9_9RHIZ/4-87                ...........................................kt-ALVLALVA.LTP......AVAMA....................SPA..CT....T..E.....P.Q......DKWM..............SQDAM....K.A.....K.VA....E....LG.Y..T...I..K....TFQ..V..-....S.GNC......YEIY...G....FT..K....D..NK.....RA..EVYFNPVTGDVVEA-e.............
A0A0A1YQZ6_9PSED/2-85                ............................................r-AIVLSFLA.FLS......PLALA....................KTE..CT....T..A.....D.Q......TTWQ..............DQDDF....Q.Q.....E.LV....L....QG.Y..E...I..K....KFK..V..T....G.GNC......YEIY...G....YD..K....D..KR.....KV..EIYFDPVSGKVVKHE..............
I4VYH0_9GAMM/90-152                  .......................................ypedev---------.---......-----....................---..--....-..-.....-.-......-SKL..............SEADV....R.A.....S.LS....T....QG.Y.tD...V..H....DVD..F..D....D.G-V......WKAK...A....KN..A....A..GN.....KV..KLRLDPSTGKVIGK-d.............
G9ZUL1_9PROT/5-87                    ............................................l-AALGLALT.LMA......GTGVA....................-LA..ED....R..A.....P.T......AEE-..............-RSRI....E.G.....A.LR....S....QG.F.nD...W..G....RIE..L..D....D.G-I......WKID..dA....RG.gQ....N..DR.....RR..DIRLTPDDLRLI---dts...........
A0A0Q5MKJ1_9BURK/8-93                ...........................................rl--ATAALLA.LGA.....cSSAFAh..................gKVE..CP....E..H.....P.K......AEWR..............PHTEL....Q.Q.....K.LE....K....EG.W..V...V..R....RME..K..T....P.T-C......YEVY...A....KD..P....Q..GK.....RI..EAFFDPKTFERVEE-r.............
A4YYE7_BRASO/3-88                    .........................................lita-ALLGAALA.GFA.....iSPAMAd..................gYKT..CT....K..L.....D.K......AQWK..............PAAEA....E.A.....K.AK....D....AG.Y..E...V..R....RSK..V..-....E.GSC......YEVY...G....-V..K....G..GK.....LY..ELFYSPEDLS-----lkh...........
G4QMW8_GLANF/5-86                    ...........................................fh--MLLIASS.LTS......AASFA....................-SD..SC....N..D.....P.I......DKWQ..............PQENL....Q.K.....K.LE....I....KG.W..K...V..N....RIK..I..D....D.G-C......YEAK...G....LD..T....L..GN.....RF..EAIFLPASLSISKL-e.............
A0A0A0E8T1_9RHOB/7-82                ..........................................lip---ATLMAA.TLA......GTVMA....................---..SS....Y..A.....I.P......DDL-..............-KARV....T.E.....K.LT....Q....EG.Y..E...V..R....KID..R..E....D.G-K......IEVY...-....AL..K....D..GA.....KV..ELYLDA---------dlnvtrqk......
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