GenomeNet

Database: Pfam
Entry: Phi-29_GP3
LinkDB: Phi-29_GP3
Original site: Phi-29_GP3 
#=GF ID   Phi-29_GP3
#=GF AC   PF05435.6
#=GF DE   Phi-29 DNA terminal protein GP3
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_14111 (release 8.0)
#=GF GA   25.00 25.00;
#=GF TC   449.40 449.30;
#=GF NC   21.70 20.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   6779279
#=GF RT   Protein p3 is linked to the DNA of phage phi 29 through a
#=GF RT   phosphoester bond between serine and 5'-dAMP. 
#=GF RA   Hermoso JM, Salas M; 
#=GF RL   Proc Natl Acad Sci U S A 1980;77:6425-6428.
#=GF DR   INTERPRO; IPR008770;
#=GF CC   This family consists of DNA terminal protein GP3 sequences from
#=GF CC   Phi-29 like bacteriophages. DNA terminal protein GP3 is linked
#=GF CC   to the 5' ends of both strands of the genome through a
#=GF CC   phosphodiester bond between the beta-hydroxyl group of a serine
#=GF CC   residue and the 5'-phosphate of the terminal deoxyadenylate.
#=GF CC   This protein is essential for DNA replication and is involved in
#=GF CC   the priming of DNA elongation [1].
#=GF SQ   7
#=GS TERM_BPPZA/1-266    AC P06951.1
#=GS Q9FZW9_BPGA1/1-265  AC Q9FZW9.1
#=GS TERM_BPB03/1-266    AC Q37883.1
#=GS B7SSM3_BPNF/1-266   AC B7SSM3.1
#=GS TERM_BPNF/1-266     AC P06812.1
#=GS TERM_BPPH2/1-266    AC P03681.1
#=GS TERM_BPPH2/1-266    DR PDB; 2EX3 D; 71-259;
#=GS TERM_BPPH2/1-266    DR PDB; 2EX3 B; 71-259;
#=GS TERM_BPPH2/1-266    DR PDB; 2EX3 H; 71-259;
#=GS TERM_BPPH2/1-266    DR PDB; 2EX3 J; 71-259;
#=GS TERM_BPPH2/1-266    DR PDB; 2EX3 L; 71-259;
#=GS TERM_BPPH2/1-266    DR PDB; 2EX3 F; 71-259;
#=GS B3VMN7_BPPH2/1-266  AC B3VMN7.1
TERM_BPPZA/1-266               MARSPRIRIKDNDKAEYARLVKNTKAKIARTKKKYGVDLSAEINIPDLESFETRAQFNKWKEQASSFTNRANMRYQFEKNAYGVVASKAKIAEIERNTKEVQRLVDEKINAMKDKEYYAGGKPQG.TIEQRIAMTSPAHVTGINRPRDFDFSKVRTYSRLRTLEESMEMRTDPQYYEKKMIQLQLNFIK.SVEGSFNSFDAADELIEELKKIPPDDFYELFLRISEISFEEFDSEGNTVENVEGNVYKILSYLEQYRRGDFDLSLKGF
Q9FZW9_BPGA1/1-265             MARESDFRLTKAQREEVSKLSRSVKAKTTRLLKNYGQDFTGYISPKSPDDIKSIEQFNAFKKRAESFTDRSNRDFQFVKNEYGVVVSKTELDEILSDTKKAQEVAEKILDRFNDVEVISGGQSTGfTVGENKELLAKPD-KGFGRIEDFDFNKVKTQEGLDRFANRAKKRSQEAYYEESLRRLQDNFIRnSVEGTFNS--EADDVVSKLRSLPADDFYECFSIYNEISFENFDSENALGMASESILERVRMYVNDYFEGKSDLSLKGF
TERM_BPB03/1-266               MARNSRIRITNNDKALYAKLVKNTKAKISRTKKKYGIDLSNEIELPPLESFQTRKEFNEWKRKQESFTNRANQNYQFVKNKYGIVASKAKINEIEKNTKEAQRIVDEQREEIEDKPFISGGKQQG.TVGQRMQILSPSQVTGVSRPSDFNFDDVRSYARLRTLEEGMAEKASPDYYDRRMAQMHQNFIE.IVEKSFNSYWLTDELVERLKKIPPDDFFELYLIFDEISFEYFDSEGEDVEASEAMLNKIHSYLDRYERGDVNLDLKGF
B7SSM3_BPNF/1-266              MARNSRIRITNNDKALYAKLVKNTKAKISRTKKKYGIDLSNEIELPPLESFQTREEFNKWKQKQESFTNRANQNYQFVKNKYGIVASKAKINEIAKNTKEAQRIVDEQREEIEDKPFISGGKQQG.TVGQRMQILSPSQVTGISRPSDFNFDDVRSYARLRTLEEGMAEKASPDYYDRRMTQMHQNFIE.IVEKSFNSDWLSDELVERLKKIPPDDFFELYLMFDEISFEYFDSEGEDVEASEAMLNKIHSYLDRYERGDVNLDLKGF
TERM_BPNF/1-266                MARNSRIRITNNDKALYAKLVKNTKAKISRTKKKYGIDLSNEIELPPLESFQTREEFNKWKQKQESFTNRANQNYQFVKNKYGIVASKAKINEIAKNTKEAQRIVDEQREEIEDKPFISGGKQQG.TVGQRMQILSPSQVTGISRPSDFNFDDVRSYARLRTLEEGMAEKASPDYYDRRMTQMHQNFIE.IVEKSFNSDWLSDELVERLKKIPPDDFFELYLMFDEISFEYFDSEGEDVEASEAMLNKIHSYLDRYERGDVNLDLKGF
TERM_BPPH2/1-266               MARSPRIRIKDNDKAEYARLVKNTKAKIARTKKKYGVDLTAEIDIPDLDSFETRAQFNKWKEQASSFTNRANMRYQFEKNAYGVVASKAKIAEIERNTKEVQRLVDEKIKAMKDKEYYAGGKPQG.TIEQRIAMTSPAHVTGINRPHDFDFSKVRSYSRLRTLEESMEMRTDPQYYEKKMIQLQLNFIK.SVEGSFNSFDAADELIEELKKIPPDDFYELFLRISEISFEEFDSEGNTVENVEGNVYKILSYLEQYRRGDFDLSLKGF
#=GR TERM_BPPH2/1-266    SS    XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--TTS-EEE-TTS-EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-XXXXXX.XXXXXXXXXXXXXX----------GGG--SHHHHHHHHHHHHHTTSTTHHHHHHHHHHHHHHH.HHHHHH-BSHHHHHHHHHHHTS-HHHHHHHHHHHTTT-XXXXXXX---HHHHHHHHHHHHHHHHHHHTT--XXXXXXX
B3VMN7_BPPH2/1-266             MARSPRIRIKDNDKAEYARLVKNTKAKIARTKKKYGVDLTAEIDIPDLDSFETRAQFNKWKEQASSFTNRANMRYQFEKNAYGVVASKAKIAEIERNTKEVQRLVDEKIKAMKDKEYYAGGKPQG.TIEQRIAMTSPAHVTGINRPHDFDFSKVRSYSRLRTLEESMEMRTDPQYYEKKMIQLQLNFIK.SVEGSFNSFDAADELIEELKKIPPDDFYELFLRISEISFEEFDSEGNTVENVEGNVYKILSYLEQYRRGDFDLSLKGF
#=GC SS_cons                   XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--TTS-EEE-TTS-EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-XXXXXX.XXXXXXXXXXXXXX----------GGG--SHHHHHHHHHHHHHTTSTTHHHHHHHHHHHHHHH.HHHHHH-BSHHHHHHHHHHHTS-HHHHHHHHHHHTTT-XXXXXXX---HHHHHHHHHHHHHHHHHHHTT--XXXXXXX
#=GC seq_cons                  MARssRIRIpsNDKA.YA+LVKNTKAKIuRTKKKYGlDLosEI-lPsL-SFpTRtpFNKWKcptpSFTNRAN.pYQF.KNtYGlVASKAKIsEIt+NTKEsQRlVDEphcthcDK.ahuGGK.QG.TltQRhthhSPupVTGIsRPpDFsFscVRSYuRLRTLEEuMt.+ssPpYY-++MhQhp.NFIc..VEtSFNS..huDELlEcLKKIPPDDFaELaLhhsEISFE.FDSEGpsVEssEu.l.KIhSYL-pYcRGDhsLsLKGF
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