#=GF ID   Porin_OmpG
#=GF AC   PF09381.14
#=GF DE   Outer membrane protein G (OmpG)
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF SE   pdb_2f1c
#=GF GA   26.50 26.50;
#=GF TC   33.10 32.00;
#=GF NC   24.80 24.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF WK   Outer_membrane_protein_G
#=GF CL   CL0193
#=GF RN   [1]
#=GF RM   16797588
#=GF RT   Crystal structure of the monomeric porin OmpG. 
#=GF RA   Subbarao GV, van den Berg B; 
#=GF RL   J Mol Biol. 2006;360:750-759.
#=GF DR   INTERPRO; IPR018981;
#=GF DR   TC; 1.B.21;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Porins are channel proteins in the outer membrane of gram
#=GF CC   negative bacteria which mediate the uptake of molecules required
#=GF CC   for growth and survival.  Escherichia coli OmpG forms a 14
#=GF CC   stranded beta-barrel and in contrast to most porins, appears to
#=GF CC   function as a monomer [1]. The central pore of OmpG is wider
#=GF CC   than other E. coli porins and it is speculated that it may form
#=GF CC   a non-specific channel for the transport of larger
#=GF CC   oligosaccharides [1].
#=GF SQ   22
#=GS A0A447M3X9_SALBN/24-299  AC A0A447M3X9.1
#=GS A0A085GDN0_9ENTR/24-301  AC A0A085GDN0.1
#=GS A0A4V3BQU0_9ENTR/24-301  AC A0A4V3BQU0.1
#=GS A0A4P7J0W1_9ENTR/24-299  AC A0A4P7J0W1.1
#=GS D1AL54_SEBTE/71-353      AC D1AL54.1
#=GS D1AH59_SEBTE/21-298      AC D1AH59.1
#=GS H5V239_ATLHE/26-305      AC H5V239.1
#=GS A0A085AIE0_9ENTR/2-279   AC A0A085AIE0.1
#=GS Q8X8K6_ECO57/24-299      AC Q8X8K6.1
#=GS D2TKA6_CITRI/24-299      AC D2TKA6.1
#=GS A0A2X4WLJ5_SALER/1-206   AC A0A2X4WLJ5.1
#=GS A0A0J5KP90_PLUGE/46-331  AC A0A0J5KP90.1
#=GS A0A2X4TCF0_SALER/24-73   AC A0A2X4TCF0.1
#=GS OMPG_ECOLI/24-299        AC P76045.1
#=GS A0A5Q2K264_9ENTR/25-302  AC A0A5Q2K264.1
#=GS A0A8H9YS63_9PSED/25-302  AC A0A8H9YS63.1
#=GS A0A1S8CN01_9GAMM/35-329  AC A0A1S8CN01.1
#=GS A9MER4_SALAR/59-347      AC A9MER4.1
#=GS A9MQ52_SALAR/24-299      AC A9MQ52.1
#=GS A0A240CCZ3_SERFI/48-331  AC A0A240CCZ3.1
#=GS D4E462_SEROD/49-332      AC D4E462.1
#=GS A0A078LGV9_CITKO/24-299  AC A0A078LGV9.1
A0A447M3X9_SALBN/24-299             ...................................................................................n-NNWHFNIGAMYEIENIEGQAeDMDGLGE...PSIYFNAAN..GPWKISLAYYQEG-PVD..YSAG.KRGTWFDR..PELEIRYQFLESDDVNVGLTGGFRNYGYHYVNEPGKD--.TANMQRWKVQPDWDIKLTDDLR.FSGWLAMYQFVND....LNITGYSDSRVESETGLNYTFNETVGLTVNYYLERGFNLAD..nRNNGEFSTQEIRAYLPISL-----GNTTLTPYTRLGLDRWSnwdWQDDPE-REGHDF...NRLGLLYAYDFQNGLSMTLEYAFEWEDHDEGESD-----KFHYAGIGINY......................
A0A085GDN0_9ENTR/24-301             ...................................................................................v-DAWHYNIGAMYEIENVEGQAdDKDGLYE...PSVYFNASY..GAWTLSMTMYQEG-SAD..YSNF.TRGTYFNR..PELDIRYQIVDNDAWSLGFTGGLRNYGYHFKNDDGSNNG.TANTQRYKFQPDWNVNINNDWS.FSGWLAYYRFDND....LDQTGYSDSRIETETGFTWKINETVSVRTNYYLERGFNTES..dKNNGEFSTQEIRAYLPIAL-----GNTTLTPYTRLGLDRWTnwdWSEDIY-REDHDY...NRLGLLYAYDFQNGLSMTLEYAYEWENHDEGEND-----TFHYAGVGVNY......................
A0A4V3BQU0_9ENTR/24-301             ...................................................................................n-DGWKFNIGAMYEIENIEGQAdDMDGLYE...PSVWFNAST..GPWKISLAMYQEG-PVD..YSSG.TRGTYFNR..PELEVRYQVLDSDDFTLGLTGGIRNYGYHFKDEHNKAAG.TANMQRYKFQPDWNLRLTDDVH.FNGWLAAYQFVND....LQQTGYADSRVETETGFTWKLTETVSLLTNYYLERGFNLDK..sRNNGEFSTQEIRAYLPISF-----GSTTLTPYTRLGLDRWTnwdWQDDPT-REGHDF...NRLGLQFAHDFDNGVSVSLEYAYEWEHHDEGDDD-----RFHYAGVGINY......................
A0A4P7J0W1_9ENTR/24-299             ...................................................................................n-NDWHFNIGAMYEIENVEGYGeDMDGLAE...PSVYFNAAN..GPWKISIAYYQEG-PVD..YSEG.KRGTWFDR..PELEVRYQFLESDDLNFGLTGGFRNYGYHYVDEPGKD--.TANMQRWKIQPDWDVKLTDDLR.FSGWLAMYQFVND....LSTTGYSDSRVESESGLNYTFNETVGLTVNYYLERGFNMDK..sRNNGEFSTQEIRAYLPLSF-----GNTTLTPYTRLGLDRWSnwdWQDDME-REGHDF...NRLGLLYAYDFQNGISMSLEYAYEWENHDEGESD-----KFHYAGIGVNY......................
D1AL54_SEBTE/71-353                 ...................................................................................w-DGWHGTFGILQETENVEGSG.DKDGLYE...PSVYFDLRK..GKWSFGMTNYNENHDFD..YSDW.TRGNYLNR..LELRAHYQFTDNDKYAVGLGAALRNYQWFHKDGTSPTTT.--NNRWLNIQPDWRYNFTSNLS.YEGWLGLYSMFND....AQENGYSDKELETESGLKYKFNDFISVRLNYYLDRGWNLGG...PTENSFNNQQIRGYVPMNFAFFGEKTTTITPYFRQGFINKS...WNAGANQANNEID...TRLGLRIDQQLPAGFAVSLEYAYEMRNQQDSAPGQKSFSKFHYTGVGLSY......................
D1AH59_SEBTE/21-298                 ekldittgayiesenhnavynssdvtvhgfrvnlnakdfplwtefvyeyrnadsssghkgdadrykvmlgsalkygnfnfnpty---------------------.-------...---------..-----------------..----.--------..----------------------------ELRI-TDMRES.SEKTTDHRFQPNWGYTFNDQWSlYNGWLFGYRQDDAyrgySEVKSWDDYFHELETGVKYKFADSQAVSFSIYNEYVKSEKSdmqYRAHKFDDWQVRIAYEKKF----DNGIAVSPFIRYSVSSKT...ENSNGVDTDHDGK...GRYGVKMGYVADNGIGVYAETYYQNEPRENTPGPDSP-------------dknrvffklgldy.........
H5V239_ATLHE/26-305                 ...................................................................................e-TRWEYTLGAMYETENVEGQAeDMDGLYE...PSVYFNAAY..GPWSINLAMYQEG-PVN..YSAM.SRGTWFNR..PEFNLRYQFIDNPDYTLGFTGGIRNYGYHFKNADGSPAG.TANTLRYKIQPDWRAKLHGNLT.FEGWLAWYRFIND....LEQTGYSDSRVETETGFTYQFNDTVSLQVHYYLERGYNASD..sHKQGEFNTNEARIFLPVSL-----GSTTLTPYTRLTIDRWSnwdWQEDGADSEDHDY...NRLGLLVAHDFNNGLAMTLEYACEWQTHREGDTHD----IFHYAGIGVSY......................
A0A085AIE0_9ENTR/2-279              ..................................................................................ts--PWHFNVGAMIESENVEGQGeDQDGLFE...PSVYFNASK..DAWRISVAMYQEG-PVN..YSDK.TRGTYFDR..PELEIRYQFIGNDNVTFGLTGGFRNYSYHFEDESGKNTG.SANMQRYKIQPDWDLKLADDWR.FSGWLALYQFGHD....LDKTGYSDSRVETETGVTWSINETVSLKVNYYLERGFNMDG..nRNTGEFSTQEIRAYLPVVL-----GASTLTPYTRLGLDRWSnwdWQDDPE-REGHDF...NRIGLLYTYDFGNGLSTSLEYAHEWENHDEGKSD-----KFHYVGVGVNY......................
Q8X8K6_ECO57/24-299                 ...................................................................................k-NDWHFNIGAMYEIENVEGYGeDMDGLAE...PSVYFNAAN..GPWRISLAYYQEG-PVD..YSAG.KRGTWFDR..PELEVHYQFLESDDFSFGLTGGFRNYGYHYVDEPGKD--.TANMQRWKIAPDWDVKLTDDLR.FNGWLSMYKFAND....LNTTGYADTRVETETGLQYTFNETVALRVNYYLERGFNMDD..sRNNGEFSTQEIRAYLPLTL-----GNHSVTPYTRIGLDRWSnwdWQDDIE-REGHDF...NRVGLFYGYDFQNGLSISLEYAFEWQDHDEGDSD-----KFHYAGVGVNY......................
D2TKA6_CITRI/24-299                 ...................................................................................n-NDWHFNVGAMYEIENVEGQGeDMDGLAE...PSIYFNAAN..GPWKISLTYYQEG-PVD..YSAG.TRGSWFDR..PELEVRYQFLESDAVSIGLTGGFRNYGYHYVNEPGKD--.TANMQRWKVQPDWDIKISDDVR.FGGWLSMYQFVND....LSTTGYADSRVETETGFTWSINDTFSVVTNYYLERGFNLDS..sRNNGEFSTQEIRAYLPIAL-----GNTTLTPYTRIGLDRWSnwdWQDDIA-REGHDF...NRLGMLYAYDFQNGLSMTLEYAFEWQDHDEGDSD-----KFHYAGVGVNY......................
A0A2X4WLJ5_SALER/1-206              ....................................................................................---------------------.-------...---------..-----------------..----.--------..----MRYQFLESADFNFGLTGGFRNYGYHYVNEEGKD--.TANMQRWKIQPDWDVKLTDDLR.FSGWLAMYQFVND....LSITGYSDSRIETETGLNYTFNETVGFTVNYYLERGFNLAE..hRNNGEFSTQEIRAYLPISL-----GNTTLTPYTRLGLDRWTnwdWQDDPE-REGHDF...NRLGLLYAYDFQNGLSMTLEYAYEWEDHDEGESD-----RFHYAGIGVNY......................
A0A0J5KP90_PLUGE/46-331             ...................................................................................t-REWQIKTGLLLETENIEGNS.DGKGAWE...PSVYLELIK..DRWTLGGSFYQEDHNTShyYRLK.GRNDGYDQ..YEITARYALVTSKTLALGMMGGIRNYRWSYYTGDNKGQT.-YNTQRYTLQPDWNLQLIPDLH.FSGWLAMSQFKNN....VNRNGLTHNEIESETGINFAFNETLGVTLNYYIDRGWNKYS...ERDGEFSQQEMRLYFPVIFNLFSVNESKFSPYIRRTLTTWY...YNHDHQRNERERD...SRFGLLFEQALPHNLALSLEYGYELQLHPDASGNEPSRTKFHYTSIGLSY......................
A0A2X4TCF0_SALER/24-73              ...................................................................................n-NDWHFNIGAMYEIENVESQSeDMDGLGE...PSIYFNASN..GP---------------..----.--------..---------------------------------------.----------------------.-------------....-----------------------------------------...-----------------------------------------...-------------...--------------------------------------------------gvlrwpiirk............
OMPG_ECOLI/24-299                   ...................................................................................r-NDWHFNIGAMYEIENVEGYGeDMDGLAE...PSVYFNAAN..GPWRIALAYYQEG-PVD..YSAG.KRGTWFDR..PELEVHYQFLENDDFSFGLTGGFRNYGYHYVDEPGKD--.TANMQRWKIAPDWDVKLTDDLR.FNGWLSMYKFAND....LNTTGYADTRVETETGLQYTFNETVALRVNYYLERGFNMDD..sRNNGEFSTQEIRAYLPLTL-----GNHSVTPYTRIGLDRWSnwdWQDDIE-REGHDF...NRVGLFYGYDFQNGLSVSLEYAFEWQDHDEGDSD-----KFHYAGVGVNY......................
A0A5Q2K264_9ENTR/25-302             ...................................................................................a-KQWDFNIGAMYEIENVEGQGdDKDGLYE...PSVWFNATW..DAWTISLAMYQEG-PVD..YSSM.TRGTYFDR..PEIELRYRFIGTDDFTFGLTGGFRNYGYHFKDEHGAKDG.SANMQRYKIQPDWDIKLTDDWR.FGGWLSLYQFAND....LEKTGYADSRVETETGFTWTLNETFSAKVNYYLERGFNMDS..sRNNGEFSTQEIRAYLPVSL-----GQTTLTPYTRLGLDRWSnwdWRDDP-EREGHDF...NRLGLLYAYDFNNGLSMTLEYAYEWENHDEGDSD-----RFHYAGVGVNY......................
A0A8H9YS63_9PSED/25-302             ...................................................................................v-KKWDFNIGAMYEIENVEGQGdDKDGLYE...PSIWFNATY..DAWTVSLAMYQEG-PVD..YSSM.TRGTYFDR..PEFQLRYRFIDSDDFTLGLTGGFRNYGYHFKDEHGAKDG.SANMQRYKIQPDWDLKLSDSWR.FNGWFAMYQFAND....LEKTGYSDSRVETETGFTWTMNKTFSIKTNYYLERGFNLDG..gRNNGEFSTQEIRAYVPIAM-----GQTTLTPYTRIGLDRWSnwdWQDDPE-REGHDF...NRLGMLYAYDFANGLSMTLEYAYEWQNHDEGKND-----RFHYAGVGVNY......................
A0A1S8CN01_9GAMM/35-329             ..................................................................................al--PWKINTNTFLEVEDFKGHRvNGERVFDkvsPALQLGLNKpdSDWSYFMEYKASMRNYT..TNYE.SRPTSYNRnrLQLQANRKLYKGTDGNLNLSLVYRKESNDVRAEQPPKNS.---YHSYWLIPSGGYNFNEQLS.FVFWDAGYYYDNT....FSGPYINQWEWESEHGFQYRFNDSFSAKLMYYTDWTWNSSG...TKT--WEQNQIRGYFPTKI----NEEWNLQPYFRFFLSEKN...YNPLTGETTNSADlggLRLGLIVNYNLTSKVTLWSNVAWETTHWDKSKNNQV--------------vtitygdnnrqdfrlysvgvky
A9MER4_SALAR/59-347                 ...................................................................................s-KPWKVRAGLLIETENKEGQSfDKDGFFE...PTLWMDFSR..DRWTFYGSYYQETHGTN..YSDGfSRDNWFNQ..YEFDARYLMVDQKDLALGMTFHFRNYTFIYQDNPEKTQSgGYNSQRWSFQPDWRINFTDKFK.STGWVTVYNWYNN....LHENGLANRELKGEGGFEYRFNPTIAVRLNYFIDRGWNTNS..dDQTGEFCRSQLRPYIPITFSLFDAGPTTITPYGRWTLDVWS...QNASRNQRMHTTE...TRTGIFIEQKLSPHLSMTLDYAYEVQARHDLSPGDKPIVKFHKTGLGFIY......................
A9MQ52_SALAR/24-299                 ...................................................................................n-NDWHFNVGAMYEIENVESQSeDMDGLGE...PSIYFNASN..GPWSIALAYYQEG-PVD..YSAG.NRGTWFDR..PELEVRYQFLESADFNFGLTGGFRNYGYHYVNEEGKD--.TANMQRWKIQPDWDAKLNDDLH.FSGWLAMYQFVND....LSITGYSDSRIETETGLNYTFNETVGFTVNYYLERGFNLAE..hRNNGEFSTQEIRAYLPISL-----GNTTLTPYTRLGLDRWTnwdWQDDPE-REGHDF...NRLGLLYAYDFQNGLSMTLEYAYEWEDHDEGESD-----RFHYAGIGVNY......................
A0A240CCZ3_SERFI/48-331             ....................................................................................EKTWHITTGLLIETENVEGQS.DNKGFWE...PTLYLEAAR..GNWSIYGSFYQENHNGAhyYGTQ.GRSDWFNQ..YEINLRYLIASHAVYDLGLMAGVRHYRWQYKQQDGIT--.RYQTQRYTVQPDWEIRLGDQTH.FSGWLALYQYINH....IGQNALTDKELEGETGFGYQVNDLLSFKLNYYIDRGWNSGS...DRLAEFSQQELRLYVPLTLSLWH-TPLTVTPYLRHSLDTDY...YNVEQQRNDGETD...TRIGLSLELTLPEGVALSLEYAYELQRHHGTADDAGSNGKYHYTGVGLSY......................
D4E462_SEROD/49-332                 ....................................................................................EKTWHITTGLLIETENVEGQS.DNKGFWE...PTLYLEAAR..GNWSIYGSFYQENHNGAhyYGTQ.GRSDWFNQ..YEINLRYLIASHAVYDLGLMAGVRHYQWQYKQQDGIT--.RYQTQRYTVQPDWEIRLGDQSR.FSGWLALYQYINH....VRQNALTDKELEGETGFGYQVNDLLSFKLNYYIDRGWNSGS...DRLAEFSQQELRLYMPLTLALWH-TPLTVTPYLRHSLDTDY...YNVEQQRNDGETD...TRIGLLLEQTLPQGIALSLEYAYELQRHHGTADDAGSNGKYHYTGVGLSY......................
A0A078LGV9_CITKO/24-299             ...................................................................................n-NDWHFNIGAMYEIENVEGYGeDMDGLGE...PSIYFNAAT..GPWKISLAYYQEG-PFD..YSAG.KRGTWFDR..PELEVRYQFLESDDVNFGLTGGFRNYGYHYVNEAGKD--.TANMQRWKVQPDWDVKLTDDLR.FSGWLAMYQFVND....LSITGYSDSRVESETGLNYTFNETVGLTVNYYLERGFNLAE..nRDNGEFSTQEIRAYLPIAL-----GNTTLTPYTRIGLDRWSnwdWQDDPE-REGHDF...NRLGLLYAYDFQNGLSMSLEYAFEWEDHDEGESD-----KFHYAGIGINY......................
#=GC seq_cons                       ...................................................................................t.psW+aNlGAMhEhENVEGpu-DhDGLhE...PSlYFNAup..GsWpluhuhYQEs.sss..YSst.sRGoaFsR...ElplRYphl-scchshGLTGGhRNYuYHahs-sGps...oANhQRaKlQPDWcl+LsDch+.FsGWLAhYpFsND....LppTGYuDoRlEoETGhsYphN-TlulplNYYLERGaNhss..p+ssGEFSTQEIRuYlPlsl.....GsoTlTPYTRlGLDRWoNWDWp-D.p.REGHDa...NRlGLlauYDFpNGLShoLEYAaEWpsHDEGcsD.....+FHYsGlGlsY......................
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