GenomeNet

Database: Pfam
Entry: Pox_VLTF3
LinkDB: Pox_VLTF3
Original site: Pox_VLTF3 
#=GF ID   Pox_VLTF3
#=GF AC   PF04947.12
#=GF DE   Poxvirus Late Transcription Factor VLTF3 like 
#=GF AU   Finn RD, Iyer L
#=GF SE   Iyer L
#=GF GA   25.00 25.00;
#=GF TC   61.30 59.50;
#=GF NC   24.90 23.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   8523544
#=GF RT   The A2L intermediate gene product is required for in vitro
#=GF RT   transcription from a vaccinia virus late promoter. 
#=GF RA   Hubbs AE, Wright CF; 
#=GF RL   J Virol 1996;70:327-331.
#=GF RN   [2]
#=GF RM   16494962
#=GF RT   Evolutionary genomics of nucleo-cytoplasmic large DNA viruses. 
#=GF RA   Iyer LM, Balaji S, Koonin EV, Aravind L; 
#=GF RL   Virus Res. 2006;117:156-184.
#=GF DR   INTERPRO; IPR007031;
#=GF CC   Members of this family are approximately 26 KDa, and are
#=GF CC   involved in trans-activator of late transcription [1].
#=GF SQ   28
#=GS L1JNN8_GUITH/39-206   AC L1JNN8.1
#=GS Q98271_MCV1/42-202    AC Q98271.1
#=GS Q9Q8Y8_RFVKA/38-198   AC Q9Q8Y8.1
#=GS Q08FQ1_DPV83/38-198   AC Q08FQ1.1
#=GS E3T5B2_CROVB/178-343  AC E3T5B2.1
#=GS YR430_MIMIV/85-249    AC Q5UQM5.1
#=GS Q070C9_CPRVZ/39-199   AC Q070C9.1
#=GS Q6TVP3_ORFSA/38-198   AC Q6TVP3.1
#=GS 001R_FRG3G/79-253     AC Q6GZX4.1
#=GS Q9EMK1_AMEPV/39-198   AC Q9EMK1.1
#=GS Q8QUP9_ISKNN/101-264  AC Q8QUP9.1
#=GS VLTF3_VACCW/38-198    AC P68319.1
#=GS Q6TUS6_YMTV5/38-198   AC Q6TUS6.1
#=GS VF282_IIV6/195-379    AC Q91FP2.1
#=GS YR429_MIMIV/261-427   AC Q5UQM6.1
#=GS VLTF3_VAR67/38-198    AC P68320.1
#=GS VF385_ASFB7/195-374   AC Q65170.1
#=GS K3XCZ4_PYTUL/67-223   AC K3XCZ4.1
#=GS Q0E572_SFAVA/217-392  AC Q0E572.1
#=GS Q4A276_EHV8U/195-362  AC Q4A276.1
#=GS VF282_IIV3/200-390    AC Q196Y1.1
#=GS D2XAY0_GBMV/177-341   AC D2XAY0.1
#=GS Q8V3K7_SWPV1/38-198   AC Q8V3K7.1
#=GS Q9Q8L0_MYXVL/38-198   AC Q9Q8L0.1
#=GS Q8QNH7_ESV1K/147-315  AC Q8QNH7.1
#=GS D8LPD2_ECTSI/147-315  AC D8LPD2.1
#=GS Y494R_PBCV1/189-356   AC Q98544.1
#=GS VLTF3_FOWPN/39-199    AC Q9J566.1
L1JNN8_GUITH/39-206              .........k-DNSHYSYKR....INHFREWCNQIQGKESTD........IPNDVFEKILNELKKEKIT.................nTKELSYKTMRNILKKLK...I.NKYYEHINYIINRINGVPTPQFSPELEEKLCNMFKEIQGPF-LKHCP..........PNRKNFLSYSYVLYKLCQIL.....GQDEYLKHFPLLKSRIKIFQMD...LIWKNICESI...GY--py...
Q98271_MCV1/42-202               .........k-RSNFHVSNK....LIHLRNVLRRLLSKQ---........CSGDIIAELRALMARNQLA..................PADIDANFVSSFLKAHE...-.KINKKDYKLVFEIINQIKDERLELDTQK-----INEVIEIFKHLVFFc.......qeNTPSKTINYSFFLDKIFTLT.....SVTRNLRP-QTVKNYTKNNSNQ...LIWENFLVYM...RGK-k....
Q9Q8Y8_RFVKA/38-198              ..........KKSNFHVSNK....LIHLRNVLRRLLSSQ---........CSGEIISELLELMQRNQIS..................TNDVDANFVSSFLKAHE...-.RINKKDYKLVFEIINQVKREKLNLTTEK-----INEVVEIFKHLVFFc.......qeNTPSKTINYSFFLDKIFDIT.....LVTKNLKP-QTVKNYTKNNSNQ...LIWENFLSYM...KTK-k....
Q08FQ1_DPV83/38-198              ..........KKSNFHVSNK....LIHLRNVLRRLLSNQ---........CSGEIITELLELMNKNQIS..................ATDVDANFVSSFLKAHE...-.RINKKDYKLVFEIINQVKEEKLNLTTEK-----INEVVEIFKHLVFFc.......qeNTPSKTINYSFFLDKIFDIT.....NVTKNLKP-QTVKNYTKNNSNQ...LIWENFLSYM...RNK-k....
E3T5B2_CROVB/178-343             ......kdis------CYHR....SGRFKEWLNQFQAKENAD........IEDWVYLEIIKELNKKRIT.................eYSALNRTIIREILRKLK...L.TKYYDNVTFIINKLNNIPAPKISHTLEKKLLFMFDMIEDIW-AIVKP..........KNRKNMLSYPYILHKLCELL.....EEDKLLSSFPLLKSQDVLREQD...IIWKRICNKL...NWEF.....
YR430_MIMIV/85-249               ........vp---SKIFFSK....TTFFKIKLDEIMSCHNIT........ISD--LNSIKNKIESKNLQ..................IDEINTIIIGKILKKLG...L.YKYHGHEQYILNIIIGKPVQKMSSQEKNLIMKLFDQVLVTFNLLKKK..........YNWNNFLHYGYLIYQLCKLL.....EYNDFLDNIALPNNETIIYVNN...QAWKKICSHN...NWIY.....
Q070C9_CPRVZ/39-199              ..........KKSSFHVSNK....LIHLRNVLRRLLSRQ---........CSSHIIDEIMTDIERYNIS..................SQDVDANFVSNFLKEKD...-.KINKKDYKLVFEIINHVRNDTLNLTTEK-----INEIVEIFKLLVFFt.......qeNTESKTINYSFFLDKIFNVI.....GVTANLKP-QTVKNYAKNNYNQ...LTWEKFLRFL...DGK-c....
Q6TVP3_ORFSA/38-198              .........k-RSNFHVSNK....LIHLRNVLRRLLSKQ---........CSEEVIRDLRAMMDRHQIR..................PEDVDANYVSSFLKDSE...-.MINKKDYKLVFEIINQVKNEKLDLSTEK-----INEVIEIFKQLVFFc.......qeITPTKTINYSFFLDKIFEVT.....GVTRNLRP-QTVKNYAKNNSNQ...LTWENFLAHM...RA--rk...
001R_FRG3G/79-253                ........aq--ASEVDVNKmccwVSKFKDAMRRYQGIQTCK........IPGKVLSDLDAKIKAYNLTvegv.........egfvrYSRVTKQHVAAFLKELR...H.SKQYENVNLIHYILTDKRVD-IQHLEKDLVKD-FKALVESAHRMRQG..........----HMINVKYILYQLLKKH.....GHGPDGPDILTVKTGSKGVLYD...DSFRKIYTDL...GWKF.....
Q9EMK1_AMEPV/39-198              .........t-TISSASNNK....TIHCNNVLKEISNTS---........ISYDIVDGFLKLINDNNLN..................TKSITTALGSEYLKSKG...I.KNYRTTHKLINMSLSDGNNCILTKDDIFRINIIFEDFTQFIYK----..........NNYTKTISYEFCLDRIFDIL.....NINYVINF-----NYSKLNKRDdkpEIWNKYIIEL...----ynksl
Q8QUP9_ISKNN/101-264             rryvdqlhsy----------....-------IYLYQGVTNSKfp....vhIPNSVLVNIRDHLQKYRIK..................EADVTLQQVLSILKVNK...H.VKYYDYATIIYRMLTGKAEV-LPPDVVAAVQA---DIVRLADAAMASp.......diWTLCTQAGATYVFFQLLRHN.....GYEYNCHTFMQAKTLSKKQSQD...VACNALCDRM...SWTF.....
VLTF3_VACCW/38-198               ..........KKSNFHVSNK....LIHLRNVLRRLLSHQ---........CSGEIISELLDIMEKNQIS..................TDDVDANFVSSFLKANE...-.RINKKDYKLVFEIINQVKDEKLNLSTEK-----INEVVEIFKHLVFFc.......qeNTPSKTINYSFFLDKIFDIT.....SVTKNLKP-QTVKNYTKNNSNQ...LVWENFLAHM...RSK-k....
Q6TUS6_YMTV5/38-198              .........k-RSNFHVSNK....LIHLRNVLRRLLSNQ---........CSGEIISEILSLMEKNQIS..................TDDVDANFVSSFLKAHE...-.KINKKDYKLVFEIINHVKDEKINLTTEK-----INEVVEIFKHLVFFc.......qeNTPSKTINYSFFLDKIFDIT.....SVTKNLKP-QTVKNYTKNNSNQ...LIWENFLDHM...KNK-k....
VF282_IIV6/195-379               .........n-VCNKYTYDR....KVHFKDCINQYQGKQNTN........INPRIYDELEEQLVNHQIIepankkdkfgnpisqskrFKIVTRAHILFFLKELG...Y.TKHYEDTILIHYTLTGKRPDNIEHLEEKLMAD-FDKLTEQYDLLFKD..........IERKNFINTQYVLFQLLRKH.....GYNCNKDDFAVLKTTERKACHD...DICKTLFDAL...GWKY.....
YR429_MIMIV/261-427              .........q-DSGTYAYKR....INHLTEILSQLQAKESTD........IPNKVYEAIKRELKKRKID..................KNDLDIFRLRRILKKLN...Y.RKFYEHVPHILQVINGKEPPNFSRADEMKIKALFKSIQKPF-AIYCP..........KNRKNFLNYSYVLHKFCELL.....ELDEYTNYFPLLKNNAKLLQHD...KIWKNICDYQ...GWYF.....
VLTF3_VAR67/38-198               ..........KKSNFHVSNK....LIHLRNVLRRLLSHQ---........CSGEIISELLDIMEKNQIS..................TDDVDANFVSSFLKANE...-.RINKKDYKLVFEIINQVKDEKLNLSTEK-----INEVVEIFKHLVFFc.......qeNTPSKTINYSFFLDKIFDIT.....SVTKNLKP-QTVKNYTKNNSNQ...LVWENFLAHM...RSK-k....
VF385_ASFB7/195-374              .........a-KSGIFNPNR....--HYRFWIEHILGRNPEQelgtkqdpCGTKVLQQLKKIIKRDNKC..................IALLTVENIRKMLKEIN...R.TDLNNCVSLILRKLTGVGPPQISESILLRGEYIFTEAIKIREKVCKK..........-GRINRNYYPYYIYKIFDAIlppndTTNRRILQYIHLQGNDTLANND...SEWESICMELpeiKWK-.....
K3XCZ4_PYTUL/67-223              ...ffsqegm----------....-------------RETNT........ISEKQLNKIETCIKRGGIT.................nKKKITIEQLGQYLKDAD...L.AELNEHVALIKRLITGIIPPQLTYSETQDITNSFSKAVKAY-NIIRP..........SNKSNMLFYLFLLWKLIEMHvs.dyNKRKNLLSFIHLQGTQTLIQND...HIWMQICEIT...----ssfhy
Q0E572_SFAVA/217-392             ........tg---GNNVYNR....TMHFRDCLYQYQGVHTPV........LAAEVFESLIKAMRECNIMgntg.........drerdAANVTKGDVLYYLKQLN...Y.TRHYDDAVYIHRVITGRSSDNVQHLEERLIHD-FTLLSKKYDEQHAG.........kRERRSFINMQIVLYQLLRRY.....GHDCKLEDFASIKSLEQRARRD...ELYKELFTSL...GWKY.....
Q4A276_EHV8U/195-362             ........vf--NQSFSYKR....SNHFTEWLIRTQAKETYV........VPDDVIKKVMEGLALRNVH..................PDEVDQHIVLDILKKNK...MkSKTYRYTAQITMKCTGVPPPRLTSEMDQLAGLIFIAIQEPF-NKYMP..........ADRKNFLSYSYCIYRIYELM.....GADDLLPTLSLLSGTGKIPPQD...AVMKKIYNEM...EWDW.....
VF282_IIV3/200-390               ..........NMASKYTYNR....KVHFRDCITQYQGKQKTH........IPEEIYTILETKLLEKNLLntepg.......ltvekrYEKVTRAMVLDILKELGskdV.KKFYDDIVLIHHTLTKQPCDNIEYLEDSLLDD-FDKLTETYDNLYVNqdspdderggTKRKNFINAQFVLYQLLRKH.....NHPCNSMDFLTLKKSERKRFHH...TICKKLFSIL...EWKY.....
D2XAY0_GBMV/177-341              .gsskpgyvt----------....KLQFLEVIEKFQAKKNTR........IPLEVKEKIVSELKKYGIP..................LESVTKKHIYMVLVDNN...L.TDYYEELSLLLWELNGTLPPDISAYQEELSNC--YDVYEKVYLQIKE..........KERRKSLNAWYVLYKLLQHL.....KYTPNPDDFCFLKNTMKTRDCD...EKFLEVCKRL...GWN-d....
Q8V3K7_SWPV1/38-198              ..........KKSNFHVSNK....LIHLRNVLRRLLSNQ---........CSGDIITELLELMDKNQIS..................SEDIDANFVSNFLKAHE...-.RINKKDYKLVFEIINQVKDEKLNLTTEK-----INEVVEIFKHLVFFc.......qeKTPSKTINYSFFLDKIFDIT.....HVTKNLKP-QTVKNYTKNNSNQ...LIWENFLIYM...KTK-h....
Q9Q8L0_MYXVL/38-198              ..........KKSNFHVSNK....LIHLRNVLRRLLSSQ---........CSGEIISELLELMQRNQIS..................TNDVDANFVSSFLKAHE...-.RINKKDYKLVFEIINQVKREKLNLTTEK-----INEVVEIFKHLVFFc.......qeNTPSKTINYSFFLDKIFDIT.....LVTKNLKP-QTVKNYTKNNSNQ...LIWENFLSYM...KTK-k....
Q8QNH7_ESV1K/147-315             ........vs--HTTYMYKR....QNHFKTWLKRTQGKETTT........VDKEVVDSVRLELKKQRID.................dIKTISHTKVREILKKLR...L.NKHYNNCVQITAMITGITPPQMTSEQETALLQMFDAIQTPFQKIIQS..........EPRQNMLSYSFLIHKFLELM.....SWDEYLPYFPLLRSVDKIQYQD...WIWRKLCAEV...GFEY.....
D8LPD2_ECTSI/147-315             ........vs--HTTYMYKR....QNHFKTWLKRTQGKETTT........VDKGVVDSVRFELKKQRID.................dIRTISHTKVREILKKLR...L.NKHYNNCVQITAIITGVTPPQMTNEQETALLQMFDAIQEPFQKIIRS..........EPRQNMLSYSFLIHKFLELM.....SWDEYLPYFPLLRSVDKIQYQD...WIWRKLCAEV...GFEY.....
Y494R_PBCV1/189-356              ........es--NEGMAYKR....INHLAECLNALQGKEGTN........VPQEVINAVKAEFKKNRIS.................tTSEIKPSKVKQFLKKLG...Y.SMYYENIYTIANMISGIPTLKLSRELEKRLKDMFFEIQEPF-FRHKP..........PKRKNFLSYNYVLYKFSELL.....GEDDLLQYFPLLKCPKNLHNQD...VIWKKICNDL...QWEF.....
VLTF3_FOWPN/39-199               ..........KKSNFHVSNK....LIHLRNVLRRLLSNQ---........CSSDVIVELKSVMTKNNIS..................STDIDANFVSSFLKANE...-.KINKKDYKLVFEIINHIKEEKLNLDTSK-----INEVIEIFKHLVFFc.......qeNTPSKTINYSFFLDKIFSLT.....SVTNNLKP-QTVKNYTKNNSNQ...LVWENFLDYM...KKK-k....
#=GC seq_cons                    ............sshas.s+....hhHh+ssLc+l.u+p...........hss-llsclhphhc+ppIs..................hs-lstshVppaLKphc...h.phphcchpLlhplIstlpspplshspEc.....hs-lhEhFcplhh...........ps.pphlNYoahL.Klh-lh.....shscsLcs..plKshsKtsspp...hlWcphhsph...phc......
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