GenomeNet

Database: Pfam
Entry: Pox_VP8_L4R
LinkDB: Pox_VP8_L4R
Original site: Pox_VP8_L4R 
#=GF ID   Pox_VP8_L4R
#=GF AC   PF04498.7
#=GF DE   Poxvirus nucleic acid binding protein VP8/L4R
#=GF AU   Kerrison ND
#=GF SE   DOMO:DM04340;
#=GF GA   25.00 25.00;
#=GF TC   26.10 174.20;
#=GF NC   20.80 19.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9321647
#=GF RT   Vaccinia virion protein VP8, the 25 kDa product of the L4R gene,
#=GF RT   binds single-stranded DNA and RNA with similar affinity. 
#=GF RA   Bayliss CD, Smith GL; 
#=GF RL   Nucleic Acids Res 1997;25:3984-3990.
#=GF DR   INTERPRO; IPR007586;
#=GF CC   The 25 kDa product of Vaccinia virus gene L4R is also known as
#=GF CC   VP8.	VP8 is found in the cores of Vaccinia virions and is
#=GF CC   essential for the formation of transcriptionally competent viral
#=GF CC   particles.  It binds both single stranded and double stranded
#=GF CC   DNA and RNA with similar affinities.	Binding is thought to
#=GF CC   involve cooperative interactions between protein subunits. The
#=GF CC   protein is proteolytically cleaved during viral assembly at an
#=GF CC   Ala-Gly-Ala site. Possible roles for VP8 include packaging and
#=GF CC   maintaining the DNA genome in a transcribable configuration;
#=GF CC   binding ssDNA during transcription initiation; and cooperation
#=GF CC   with I8R protein to unwind early promoter regions.  VP8 may also
#=GF CC   function in either transcription elongation or release of mRNA
#=GF CC   molecules from viral particles [1].
#=GF SQ   58
#=GS VP8_VACCW/33-249     AC P03295.1
#=GS Q6RZL1_9POXV/33-249  AC Q6RZL1.1
#=GS E2CZV3_9POXV/33-249  AC E2CZV3.1
#=GS Q76Q15_VARV/33-249   AC Q76Q15.1
#=GS Q6TVS0_ORFSA/32-250  AC Q6TVS0.1
#=GS Q8V4Z9_MONPV/33-249  AC Q8V4Z9.1
#=GS Q98241_MCV1/31-251   AC Q98241.1
#=GS Q0NLX7_VAR66/33-249  AC Q0NLX7.1
#=GS Q0GNZ3_HSPV/33-249   AC Q0GNZ3.1
#=GS O11328_MCV1/1-126    AC O11328.1
#=GS Q0NPB7_9POXV/33-249  AC Q0NPB7.1
#=GS Q8V2T2_CAMPM/33-249  AC Q8V2T2.1
#=GS Q6VZH1_CNPV/31-252   AC Q6VZH1.1
#=GS Q9Q8N8_MYXVL/33-249  AC Q9Q8N8.1
#=GS VP8_VACCC/33-249     AC P20981.1
#=GS Q08FB0_DPV84/33-250  AC Q08FB0.1
#=GS G3EIE9_9POXV/33-249  AC G3EIE9.1
#=GS Q0N570_VARV/33-249   AC Q0N570.1
#=GS VP8_VAR67/33-249     AC P33039.1
#=GS Q0NG62_VAR46/33-249  AC Q0NG62.1
#=GS B9U1H3_9POXV/33-249  AC B9U1H3.1
#=GS Q77GM4_LSDV/33-251   AC Q77GM4.1
#=GS Q91MU5_LSDV/33-251   AC Q91MU5.1
#=GS Q77GD3_LSDV/33-251   AC Q77GD3.1
#=GS Q9DHQ0_YLDV/33-249   AC Q9DHQ0.1
#=GS Q1M1M8_9POXV/33-249  AC Q1M1M8.1
#=GS Q8V3N4_SWPV1/34-251  AC Q8V3N4.1
#=GS Q08FT0_DPV83/33-250  AC Q08FT0.1
#=GS Q49PP2_9POXV/33-249  AC Q49PP2.1
#=GS B2CWG5_9POXV/33-249  AC B2CWG5.1
#=GS Q2F8C5_ORFV/32-250   AC Q2F8C5.1
#=GS I0AZF0_9POXV/33-249  AC I0AZF0.1
#=GS Q070F8_CPRV/31-241   AC Q070F8.1
#=GS G0XUM9_COWPX/33-249  AC G0XUM9.1
#=GS Q775V4_CAMPS/33-249  AC Q775V4.1
#=GS Q6TUV0_YMTV5/33-250  AC Q6TUV0.1
#=GS Q77TK7_VACCT/33-249  AC Q77TK7.1
#=GS Q76RD0_9POXV/33-249  AC Q76RD0.1
#=GS G0XX33_COWPX/33-249  AC G0XX33.1
#=GS Q0NEF6_VARV/33-249   AC Q0NEF6.1
#=GS D3IZJ7_9POXV/32-250  AC D3IZJ7.1
#=GS Q9Q913_RFVKA/33-249  AC Q9Q913.1
#=GS A7XCI6_9POXV/33-249  AC A7XCI6.1
#=GS F1AX34_ORFV/32-250   AC F1AX34.1
#=GS G0XVV8_COWPX/33-249  AC G0XVV8.1
#=GS Q6TW50_ORFV/32-250   AC Q6TW50.1
#=GS Q76TT4_9POXV/31-251  AC Q76TT4.1
#=GS Q0NCP5_VAR65/33-249  AC Q0NCP5.1
#=GS Q8JLD8_9POXV/33-249  AC Q8JLD8.1
#=GS VP8_FOWPN/32-253     AC P15913.1
#=GS Q89214_VARV/33-249   AC Q89214.1
#=GS H6TA55_9POXV/35-251  AC H6TA55.1
#=GS Q6TVD8_9POXV/31-248  AC Q6TVD8.1
#=GS Q8QMX2_COWPX/33-249  AC Q8QMX2.1
#=GS D3IZ66_9POXV/32-250  AC D3IZ66.1
#=GS A9J1Q2_VACCA/33-249  AC A9J1Q2.1
#=GS Q5IXU2_MONPV/33-249  AC Q5IXU2.1
#=GS Q70H27_FOWPV/32-253  AC Q70H27.1
VP8_VACCW/33-249                AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINILNVYSPSTSIRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q6RZL1_9POXV/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
E2CZV3_9POXV/33-249             AKLKYPRSFLSIFNIVPRNMTRYELDLVQTENITGVVFTTVFNIKKNLGILE.EKLTIEAIENYYLDPNNDVLTLMIDNTSLKEI..-SPRKKSRR.TKNPVLFRQGSIPLFFIFESRKKVDIYKENVNKAV.DGSYIKIDDNVALMGKYANMSLLDVHSPSAFMKLNAVYGF.THKNELRKLVSDKEIEEYSGQP.LQEPVRLNDFIGLFDGVKKSIPLTSIP-s
Q76Q15_VARV/33-249              AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMSLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q6TVS0_ORFSA/32-250             ARVRFPRSLLSLFNVVPRTMTRYETELVGTEMVVGAVFTTAYNIRRNLGLGE.DPVTMRDIEKYFLDSDNEVLTLIVHNTDFSAM.sGVRRRGGRR.ITNPVIFRSGSTPLLIVMESRKKTNIYRERTAEQA.NASYREVGSSLALVTRYAGLQLVDVHTPSSVLTVSAVYGF.TEDKGLKKLGSDKELADYQSTP.LTDPIRLSDFSKLFDGVKKSIQLTNVP-v
Q8V4Z9_MONPV/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTTV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESV-.STEYTPIGDNKALISKYAGINILNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q98241_MCV1/31-251              AKVKFPRSLLSMYRVVPRTMSRYELALVQSETVTGVVFTTVYNVRRNLGLEErEALSLPALEKYYLDKANDVLTLMVNNTNLEHI..AAYRMRSRR.LLNPVVFRAGAVPLALVFTSRKKLSIYREDTSQAAeDSTYTKIAANVALAGKYAGLLLLDVHTPGTALMLTAVYGL.DDRRELRKLADSTALENHQQSGaLSEAMKLSDFRAVFEGLKKSVPLTNLEM.
Q0NLX7_VAR66/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMSLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q0GNZ3_HSPV/33-249              AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINILNVYSPSTSIRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECIKKNIPLTDIP-t
O11328_MCV1/1-126               ----------------------------------------------------.-------LEKYYLDKANDVLTLMVNNTNLEHI..AAYRMRSRR.LLNPVVFRAGAVPLALVFTSRKKLSIYREDTSQAAeDSTYTKIAANVALAGKYAGLLLLDVHTPGTALMLTAVYGL.DDRRELRKLADSTALE------.----------------------------.
Q0NPB7_9POXV/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q8V2T2_CAMPM/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVMNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLFECVKKNIPLTDIP-t
Q6VZH1_CNPV/31-252              AKYKFPKSLLSIYKIVPKIMTRYPMKLLTNESISGVVITTVYNLKKNLSIPEkTKLTKQDIEKYYLDKNIEVLNLMISNTSVEDLacGRQRRKRTAkRKEPVIFLGVSAPIIVLMTSKKAVNTYVQDKESDP.STDYVNITPGIAVLENYGNTRLLDVHNPSAVLTVSAVYGL.DSNMELKKLSTVAEMENYQNTN.IGKPIDLKKFTEIFSTIKKHLSLSNFTM.
Q9Q8N8_MYXVL/33-249             AKLKYPRSFLSIFNIVPRNMTRYELDLVQTENITGAVFTTVFNIKKNLGILE.EKLTIEAIENYYLDPNNDVLTLMIDNTSLKEI..-SPRKKSRR.TKNPVLFRQGSIPLFFIFESRKKVDIYKENVNKAV.DGSYIKIDDNVALMGKYANMSLLDVHSPSAFMKLNAVYGF.THKNELRKLVSDKEIEEYSGQP.LQEPVRLNDFIGLFDGVKKSIPLTSIP-s
VP8_VACCC/33-249                AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q08FB0_DPV84/33-250             AKVKYPRSFLSIFNITPRNMTKYELELVQTENITGAVFSTAFNIKKNLGITD.EKLTIEAIESYYLDPNNDVLTLMINNTSLDGV..-TPRKRSRR.NKNPVLFRQGSVPLFCIFDSRKKIGVYRENMNSPSkDNSYMQIEDNVALINKYANMSLLDVHSPSASMKLNAVYGF.THKNELRKLVSNKEIEEYSRKP.LQEPVRLNDFIGLFDSVKKNIPLTNIP-i
G3EIE9_9POXV/33-249             AKAKYPRSMLSIFNIVPRTMSKYNMEMIQNENITGAVFTTMYNVRNNIGLGN.DKLTIETIENYFLDPNNEVMSLIINNTDMSAV..-IPKKRSRKqNKNMVIFRQGSSPILCIFETRKKINIYKEDVSSS-.NNDYMPIGDNKAVISKYAGISILNVYSPSVSLRLNAIYGF.TNKNKVEKLSTNKELESYSDNP.LQEPIRLNDFIKLVESVKKSIPLIDIP-i
Q0N570_VARV/33-249              AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELELYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
VP8_VAR67/33-249                AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELELYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q0NG62_VAR46/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
B9U1H3_9POXV/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSIRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q77GM4_LSDV/33-251              AKIKYPRSFLSIFNIIPRNMTKYEMDLVQTENITGAVFTTAFNIKKNLGIVD.EKLTIESIENYYLDPNNDVLTLMINNTSLDNV..TTRKKRSKR.NKNPVLFRQGSIPLFFIFESRKKVEIYKENVDKASsDNSYMKIDDNIAVASKYANMSLLDVHSPSASMKLNGVYGF.TYKNELRKLSSDKEIDEYSNKP.LQEPVRLNDFIGLFDCVKKNIPLTNIP-i
Q91MU5_LSDV/33-251              AKIKYPRSFLSIFNIIPRNMTKYEMDLVQTENITGAVFTTAFNIKKNLGIVD.EKLTIESIENYYLDPNNDVLTLMINNTSLDNV..TTRKKRSKR.NKNPVLFRQGSIPLFFIFESRKKVEIYKENVDKASsDNSYMKIDDNIAVASKYANMSLLDVHSPSASMKLNGVYGF.TYKNELRKLSSDKEIDEYSNKP.LQEPVRLNDFIGLFDCVKKNIPLTNIP-i
Q77GD3_LSDV/33-251              AKIKYPRSFLSIFNIIPRNMTKYEMDLVQTENITGAVFTTAFNIKKNLGIVD.EKLTIESIENYYLDPNNDVLTLMINNTSLDNV..TTRKKRSKR.NKNPVLFRQGSIPLFFIFESRKKVEIYKENVDKASsDNSYMKIDDNIAVASKYANMSLLDVHSPSASMKLNGVYGF.TYKNELRKLSSDKEIDEYSNKP.LQEPVRLNDFIGLFDCVKKNIPLTNIP-i
Q9DHQ0_YLDV/33-249              AKVKYPRSFLSIFNIIPRNMTKYELDLVQTENITGAVFTTAFNIKKNLGMGD.EKLTIEAIEGYYLDPNNDILTLMINNTSLSEV..-VPKRKSKR.NKNPVLFRQGSVPLFFIFESRKKVEIYKENMESQK.DSSYSQINENIALISKYSNMHLLDIHSPSAFMKLNGVYGF.THKNELRKLSSNKEIEEYSNKP.LQEPVRLNDFINLFDCVKKNIPLTNVI-d
Q1M1M8_9POXV/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECIKKNIPLTDIP-t
Q8V3N4_SWPV1/34-251             AKIKYPRSFLSIFNIIPRNMTRYSLDLIQTENITGAVFTTVFNIKKNLGMTD.ENLTIEAIENYYLDPNNDVITLMINNTSLDFI..-NPRKKSRR.NKNPVLFRQGSVPLFFIFDSRKKVEIYKENIDKMNeNNTYTKINDNIALAGKYANLSLLDVHSPSASMKLNAVYGF.THKNELRKLSSDKEIEEYSKKP.LQEPVRLNDFIGLFDCVKKNIPLTNIP-i
Q08FT0_DPV83/33-250             AKVKYPRSFLSIFNIIPRNMTKYELELVQTENITGAVFSTAFNIKKNLGITD.EKLTIEAIESYYLDPNNDVLTLMINNTSLDGV..-TPRKRSRR.NKNPVLFRQGSVPLFCIFDSRKKIGVYRENMNSPSkDNSYMQIEDNVALINKYANMSLLDVHSPSASMKLNAVYGF.THKNELRKLVSNKEIEEYSRKP.LQEPVRLNDFIGLFDSVKKNIPLTNIP-i
Q49PP2_9POXV/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSIRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
B2CWG5_9POXV/33-249             AKLKYPRSFLSIFNIVPRNMTRYELDLVQTENITGAVFTTVFNIKKNLGILE.EKLTIEAIENYYLDPNNDVLTLMIDNTSLKEI..-SPRKKSRR.TKNPVLFRQGSIPLFFIFESRKKVDIYKENVNKAV.DGSYIKIDDNVALMGKYANMSLLDVHSPSAFMKLNTVYGF.THKNELRKLVSDKEIEEYSGQP.LQEPVRLNDFIGLFDGVKKSIPLTSIP-s
Q2F8C5_ORFV/32-250              ARVRFPRSLLSLFNVVPRTMTRYETELVGTEMVVGAVFTTAYNVRRNLGLGE.EPVTMRDIEKYFLDSENEVLTLIVHNTDFSAM.sGVRRRGGRR.IANPVIFRSGSTPLLIVMESRKKTNIYRERTAEQA.NASYREVGSSLALVTRYAGLQLVDVHTPSSVLTVSAVYGF.TEDKGLKKLGSDKELADYQSTP.LTDPIRLSDFSNIFDGVKKSIQLTNVP-v
I0AZF0_9POXV/33-249             AKSKFPRSMLSIFNIVPRTMSKYELVLIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.ATEYTPIGDNKALISKYAGINTLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q070F8_CPRV/31-241              AKLRYPKSFLSIYRVVPRNTSKYRLRKLATETLVGFAMTTMESVRKSLNV--.TTATAQQVEEYFLD--NDVVTLAVGNTDVSKL..GSYKKRSRA.-KNPVVYRKSSAPVLLVFRSKNKMDVMIEDREET-.TGTYARHEAG-AVVNTYLQTNFIDVYDPADQLTLDAVYGVpGSDLSLVKM-EGKALEKYQVTG.IQESITLSEFKELFSSAKKNIGVSNFI-q
G0XUM9_COWPX/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINILNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q775V4_CAMPS/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVMNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLFECVKKNIPLTDIP-t
Q6TUV0_YMTV5/33-250             AKVRYPRSFLSIFNIIPRNMTKYELELVQTENITGAVFTTAFNIKKNLGMND.ENLTIEAIEGYYLDPNNDILTLMINNTSLMEV..-VPKRKSKR.NKNPVLFRQGSVPLFFIFESRKKVDIYKENIENKKdSTSYSQIDENIALISKYSNMQLLDVHSPSAFMKLNGVYGF.THKNELRKLSSNKEIEEYSNKP.LQEPVRLNDFINLFDCVKKNIPLTNVI-d
Q77TK7_VACCT/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINILNVYSPSTSIRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q76RD0_9POXV/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
G0XX33_COWPX/33-249             AKSKFPRSMLSIFNIVPRTMSKYELALIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.ATEYTPIGDNKALISKYAGINILNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q0NEF6_VARV/33-249              AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
D3IZJ7_9POXV/32-250             ARVRFPRSLLSLFNVVPRTMTRYETELVGTEMVVGAIFTTAYNIRRNLGLGE.EPVTMRDIEKYFLDSENEVLTLVVHNTDFSTM.tGIRRRGGRR.IANPVIFRSGSTPLLIVMESRKKTNIYRERTADPA.NASYKEVGSSLALVTRYAGLQLVDVHTPSAVLTVSAIYGF.TEDKGLKKLGSDKELAEYQSAP.LTDPIRLGDFSKLFDGVKKSIQLTNVP-v
Q9Q913_RFVKA/33-249             AKLKYPRSFLSIFNIVPRNMTRYELDLVQTENITGAVFTTVFNIKKNLGILE.EKLTIEAIENYYLDPNNDVLTLMIDNTSLNEI..-SPRKKSKR.TKNPVLFRQGSIPLFFIFESRKKVDIYKENVNKAV.DGSYIKIDDNVALMGKYANMSLLDVHSPSAFMKLNAVYGF.THKNELRKLVSDKEIEEYSNHP.LQEPVRLNDFIGLFDGVKKSIPLTSIP-s
A7XCI6_9POXV/33-249             AKVKYPRSFLSIFNIIPRNMTKYELDLVQTENITGAVFTTAFNIKKNLGMGD.EKLTIEAIEGYYLDPNNDILTLMINNTSLSEV..-VPKRKSKR.NKNPVLFRQGSVPLFFIFESRKKVEIYKENMESQK.DSSYSQINENIALISKYSNMHLLDIHSPSAFMKLNGVYGF.THKNELRKLSSNKEIEEYSNKP.LQEPVRLNDFINLFDCVKKNIPLTNVI-d
F1AX34_ORFV/32-250              ARVRFPRSLLSLFNVVPRTMTRYETELVGTEMVVGAVFTTAYNVRRNLGLGE.EPVTMRDIEKYFLDSENEVLTLIVHNTDFSAM.sGVRRRGGRR.IANPVIFRSGSTPLLIVMESRKKTNIYRERTAEQA.NASYREVGSSLALVTRYAGLQLVDVHTPSSVLTVSAVYGF.TEDKGLKKLGSDKELADYQSTP.LTDPIRLSDFSKLFDGVKKSIQLTNVP-v
G0XVV8_COWPX/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q6TW50_ORFV/32-250              ARVRFPRSLLSLFNVVPRTMTRYETELVGTEMVVGAVFTTAYNVRRNLGLGE.EPVTMRDIEKYFLDSENEVLTLIVHNTDFSAM.sGVRRRGGRR.IANPVIFRSGSTPLLIVMESRKKTNIYRERTAEQA.NASYREVGSSLALVTRYAGLQLVDVHTPSSVLTVSAVYGF.TEDKGLKKLGSDKELADYQSTP.LTDPIRLSDFSNIFDGVKKSIQLTNVP-v
Q76TT4_9POXV/31-251             AKVKFPRSLLSMYRVVPRTMSRYELALVQSETVTGVVFTTVYNVRRNLGLEErEALSLPALEKYYLDKANDVLTLMVNNTNLEHI..AAYRMRSRR.LLNPVVFRAGAVPLALVFTSRKKLSIYREDTSQAAeDSTYTKIAANVALAGKYAGLLLLDVHTPGTALMLTAVYGL.DDRRELRKLADSTALENHQQSGaLSEAMKLSDFRAVFEGLKKSVPLTNLEM.
Q0NCP5_VAR65/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELELYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q8JLD8_9POXV/33-249             AKSKFPRSMLSIFNIVPRTMSKYELVLIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.ATEYTPIGDNKALISKYAGINILNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
VP8_FOWPN/32-253                ARSKFPKSLLSMYRVTPRVMTRYPLKLITNESITGVVITTVYNLKKNLNIPQnNKLTTQDIERYYLDKSVEVINLMVGNTSLGDLacGRPRRTKSSkKKDPVIFLGISAPLILVMNSKKSINTYIQDKKSDP.SSDYVNINPGIGVLENYGNTYLLDIHNPSSVLTISTIYGL.DNNMELKKLSTASEIDAYQDVN.IGKSVDLKKFNEIFNTMKKHLSLSNFS-i
Q89214_VARV/33-249              AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMSLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
H6TA55_9POXV/35-251             AKIKYPRSFLSIFNIIPRNVTKYELELVQNDNITGAVFTTAFNIKKNLGITD.DKLTIEAIENYYLDPNNDVLTLMTNNTTLDGI..-TPRKKSRR.NKNPVLFRQGSVPLFFIFESRKRVDIYRENMNKQN.DNSYVQIDDNIALISKYSNMTLLDVHSPSASMKLNAVYGF.THKNELKKLSTNKEIDEYSKKT.LQEPVRLNDFTGLFDCIKKNIPLTSIP-v
Q6TVD8_9POXV/31-248             ARVRFPRSLLSLFHVVPRTMTRYETELVGTEMLVGAIFSTAYNVRRNLGLGE.EPVTMRDLERYFLDSENEVLTLVVNNTDFSNL..SGVKKRGRR.IPNPVIFRSGSIPILMVLESRKKVNIYRERTDEQA.NSSYKEVGSNLAIVTRYAGLQLVDVHTPSSMLTVSAVYGV.TEDKALKKIGNDKELADYQSTP.LSDPIRLSDFTKLFDGVKKSIQLTNVP-v
Q8QMX2_COWPX/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINILNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
D3IZ66_9POXV/32-250             ARVRFPRSLLSLFNVVPRTMTRYETELVGTEMVVGAIFTTAYNIRRNLGLGE.EPVTMRDIEKYFLDSENEVLTLVVHNTDFSTM.tGIRRRGGRR.IANPVIFRSGSTPLLIVMESRKKTNIYRERTADPA.NASYKEVGSSLALVTRYAGLQLVDVHTPSAVLTVSAIYGF.TEDKGLKKLGSDKELAEYQSAP.LTDPIRLSDFSKLFDGVKKSIQLTNVP-v
A9J1Q2_VACCA/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTAV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESA-.STEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q5IXU2_MONPV/33-249             AKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGD.DKLTIEAIENYFLDPNNEVMPLIINNTDMTTV..-IPKKSGRRkNKNMVIFRQGSSPILCIFETRKKINIYKENMESV-.STEYTPIGDNKALISKYAGINILNVYSPSTSMRLNAIYGF.TNKNKLEKLSTNKELESYSSSP.LQEPIRLNDFLGLLECVKKNIPLTDIP-t
Q70H27_FOWPV/32-253             ARSKFPKSLLSMYRVTPRVMTRYPLKLITNESITGVVITTVYNLKKNLNIPQnNKLTTQDIERYYLDKSVEVINLMVGNTSLGDLacGRPRRTKSSkKKDPVIFLGISAPLILVMNSKKSINTYIQDKKSDP.SSDYVNINPGIGVLENYGNTYLLDIHNPSSVLTISTIYGL.DNNMELKKLSTASEIDAYQDVN.IGKSVDLKKFNEIFNTMKKHLSLSNFS-i
#=GC seq_cons                   AKsKFPRShLSIFNIVPRTMoKYELELlpsENITGAhFTThYNIRpNLGLGD.-KLTIEAIENYFLDPNNEVhsLlINNTDhouV...lPKKuGRR.NKN.VIFRQGSoPlLhIFEoRKKlNIYKENh-SA..sopYo.IGDNhALISKYAGlslLsVaSPSoSM+LNAlYGF.TsKNcLcKLSoNKELEsYSSoP.LQEPIRLNDFlGLh-CVKKNIPLTsIP.s
//
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