GenomeNet

Database: Pfam
Entry: Prok-RING_1
LinkDB: Prok-RING_1
Original site: Prok-RING_1 
#=GF ID   Prok-RING_1
#=GF AC   PF14446.2
#=GF DE   Prokaryotic RING finger family 1
#=GF AU   Burroughs AM, Iyer LM, Aravind L
#=GF SE   Manual
#=GF GA   29.10 29.10;
#=GF TC   29.10 29.10;
#=GF NC   29.00 28.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   21547297
#=GF RT   Functional diversification of the RING finger and other
#=GF RT   binuclear treble clef domains in prokaryotes and the early
#=GF RT   evolution of the ubiquitin system.
#=GF RA   Burroughs AM, Iyer LM, Aravind L;
#=GF RL   Mol Biosyst. 2011;7:2261-2277.
#=GF CC   RING finger family found sporadically in bacteria and archaea,
#=GF CC   and  associated in gene neighborhoods with other components of
#=GF CC   the  ubiquitin-based signaling and degradation system, including
#=GF CC    ubiquitin, the E1 and E2 proteins and the JAB-like
#=GF CC   metallopeptidase.  The bacterial versions contain transmembrane
#=GF CC   helices [1].
#=GF SQ   75
#=GS M5FYV8_DACSP/235-279    AC M5FYV8.1
#=GS L7UF71_MYXSD/11-62      AC L7UF71.1
#=GS R6T2N4_9FIRM/3-56       AC R6T2N4.1
#=GS F8DAY1_HALXS/20-54      AC F8DAY1.1
#=GS R6GQX3_9CLOT/3-57       AC R6GQX3.1
#=GS A0A011WRN3_RUMAL/3-56   AC A0A011WRN3.1
#=GS R7F8M1_9FIRM/4-57       AC R7F8M1.1
#=GS R6UCX1_9CLOT/2-55       AC R6UCX1.1
#=GS W1PIR8_AMBTC/145-184    AC W1PIR8.1
#=GS R9M659_9FIRM/3-56       AC R9M659.1
#=GS R6Y3H6_9FIRM/3-56       AC R6Y3H6.1
#=GS G9RVU5_9FIRM/3-56       AC G9RVU5.1
#=GS D4MJ04_9FIRM/4-56       AC D4MJ04.1
#=GS G0P7C0_CAEBE/640-679    AC G0P7C0.1
#=GS R7BIM2_9FIRM/3-56       AC R7BIM2.1
#=GS R5DT60_9FIRM/2-55       AC R5DT60.1
#=GS D4K3Q4_9FIRM/3-56       AC D4K3Q4.1
#=GS B0MKC4_9FIRM/4-56       AC B0MKC4.1
#=GS R6MU41_9FIRM/2-55       AC R6MU41.1
#=GS A3ZZM9_9PLAN/216-265    AC A3ZZM9.1
#=GS R5YDV8_9FIRM/3-54       AC R5YDV8.1
#=GS E6UEW2_RUMA7/3-56       AC E6UEW2.1
#=GS X1BFT7_9ZZZZ/27-77      AC X1BFT7.1
#=GS D2R359_PIRSD/219-268    AC D2R359.1
#=GS R5GQ20_9FIRM/3-56       AC R5GQ20.1
#=GS R6EIU8_9FIRM/2-59       AC R6EIU8.1
#=GS M1MJV2_9CLOT/3-54       AC M1MJV2.1
#=GS R6QRD2_9CLOT/2-55       AC R6QRD2.1
#=GS R7MRY6_9FIRM/2-55       AC R7MRY6.1
#=GS U2DGQ1_CLOS4/3-56       AC U2DGQ1.1
#=GS R6P286_9CLOT/3-56       AC R6P286.1
#=GS R6CMF0_9FIRM/3-56       AC R6CMF0.1
#=GS B0PF21_9FIRM/17-70      AC B0PF21.1
#=GS D4L8K9_9FIRM/2-55       AC D4L8K9.1
#=GS M1MYV7_9CLOT/2-53       AC M1MYV7.1
#=GS R7A710_9FIRM/2-55       AC R7A710.1
#=GS J1H3N7_9CLOT/2-55       AC J1H3N7.1
#=GS R5LJ64_9FIRM/3-56       AC R5LJ64.1
#=GS R6DEQ5_9CLOT/4-58       AC R6DEQ5.1
#=GS C0E893_9CLOT/3-56       AC C0E893.1
#=GS L0DB65_SINAD/226-274    AC L0DB65.1
#=GS B5IDG2_ACIB4/1537-1587  AC B5IDG2.1
#=GS R5MJ60_9FIRM/2-55       AC R5MJ60.1
#=GS R5Y669_9FIRM/2-55       AC R5Y669.1
#=GS R5L268_9CLOT/3-56       AC R5L268.1
#=GS R6Q9U7_9FIRM/3-56       AC R6Q9U7.1
#=GS R6RL90_9FIRM/4-56       AC R6RL90.1
#=GS K6UBZ4_9CLOT/2-54       AC K6UBZ4.1
#=GS W0U939_9FIRM/3-56       AC W0U939.1
#=GS Q0W5A9_UNCMA/33-84      AC Q0W5A9.1
#=GS K6TYA4_9CLOT/2-54       AC K6TYA4.1
#=GS R5XLT4_9FIRM/3-56       AC R5XLT4.1
#=GS W7V2Y3_RUMFL/2-55       AC W7V2Y3.1
#=GS D4LCL0_RUMC1/2-55       AC D4LCL0.1
#=GS E9SD51_RUMAL/3-56       AC E9SD51.1
#=GS G0N885_CAEBE/210-249    AC G0N885.1
#=GS R6NKW4_9CLOT/2-55       AC R6NKW4.1
#=GS K1T397_9ZZZZ/1-39       AC K1T397.1
#=GS D2R360_PIRSD/217-265    AC D2R360.1
#=GS R5UYS9_9FIRM/3-56       AC R5UYS9.1
#=GS R7KZN4_9FIRM/3-56       AC R7KZN4.1
#=GS D4JWG4_9FIRM/4-56       AC D4JWG4.1
#=GS R7NJ19_9FIRM/2-55       AC R7NJ19.1
#=GS R6DV58_9FIRM/2-55       AC R6DV58.1
#=GS R5AAE6_9CLOT/3-56       AC R5AAE6.1
#=GS D4KCM5_9FIRM/3-56       AC D4KCM5.1
#=GS U2KMF3_9FIRM/4-56       AC U2KMF3.1
#=GS L0HJL0_ACIS0/1535-1585  AC L0HJL0.1
#=GS K2SDZ0_MACPH/329-377    AC K2SDZ0.1
#=GS R6IX88_9FIRM/2-55       AC R6IX88.1
#=GS R6Q9T1_9FIRM/3-56       AC R6Q9T1.1
#=GS G0PIH3_CAEBE/700-739    AC G0PIH3.1
#=GS H8I925_METCZ/22-71      AC H8I925.1
#=GS B5IDB3_ACIB4/1537-1587  AC B5IDB3.1
#=GS R5XXX1_9FIRM/3-56       AC R5XXX1.1
M5FYV8_DACSP/235-279               ....pq--EGNDCPICYESMPPGe..eEGLVFCP.ACGNGLHRGCFE..QWGK-.-------------tpn......
L7UF71_MYXSD/11-62                 ....af--AGNTCGICQTGIEVG....EEVGTCP.ACQAPFHAECWA..ENGGC.AQYGC--------ahmpgt...
R6T2N4_9FIRM/3-56                  ......NYTGKKCFSCGEVFKDG....DDIVVCP.ECGTPYHRECYL..KEGKC.INDALHESGQSWE.........
F8DAY1_HALXS/20-54                 .....l--EGRSCPSCGGELERDvykdKDAVVCA.ECGTP-------..-----.-------------raq......
R6GQX3_9CLOT/3-57                  nyrkfg-----ECPVCNVECKID....EDIVVCP.ECGAPYHRECYN..SVGQC.VYKEKHSQGFSY-t........
A0A011WRN3_RUMAL/3-56              ......NYTGSKCICCEKRFTDD....DDIVVCP.DCGTPYHRSCYE..KNGRC.INDILHDKNVSW-l........
R7F8M1_9FIRM/4-57                  ....rh--VGQECFGCHQKLQED....DDIVVCP.ECGTPYHRACWQ..KTGHC.LNAPLHASGKSWD.........
R6UCX1_9CLOT/2-55                  ......NYYNQKCPGCHKAFNKD....DDIVVCP.VCGTPQHRECYE..KENRC.VNYDKHSKTYEWN.........
W1PIR8_AMBTC/145-184               ...grg----GLCPVCFEGMDDE....GEVVVCG.RCRNGLHRECWG..E----.-------------wkrr.....
R9M659_9FIRM/3-56                  .....h-YTGVHCPVCDKKFTDE....DDIVVCP.VCGTPHHRACYQ..QEGRC.AFEEQHIKGHTWE.........
R6Y3H6_9FIRM/3-56                  ......DYTGIKCPVCGVPFRSG....DDIVVCP.ECGAPYHRACYQ..EKGAC.IFDDLHKEGKEWK.........
G9RVU5_9FIRM/3-56                  ......DYKGCKCASCHKVLKEG....DDIVICP.ECGAPYHRECYA..AEGRC.VFSAKHGKGFEY-v........
D4MJ04_9FIRM/4-56                  .....q-FKNEKCAACGMKFFDD....EDIVVCP.ECGAPYHRECWN..RVGTC.IHSAEHGS-YEWK.........
G0P7C0_CAEBE/640-679               ....nd--PERNCYICKDDFENG....DHVLICK.TCKKPVHRSCWM..K----.-------------wla......
R7BIM2_9FIRM/3-56                  .....s-YKNEKCPVCDTEFKDG....DDIVTCP.VCGTPHHRECYN..KIGHC.INEDKHKDGFEFK.........
R5DT60_9FIRM/2-55                  .....e-FTEYKCPVCDKQFKKG....DDIVVCP.ECGAPHHRECYE..KEGHC.HFADKHGADFSFE.........
D4K3Q4_9FIRM/3-56                  ......KYYGCPCEGCGKPLTLQ....DDIVVCP.DCGAPYHRDCYE..KLGQC.IHRPAHAAGCEWK.........
B0MKC4_9FIRM/4-56                  .....q-FKNEKCAACGMKFFDD....EDIVVCP.ECGAPYHRECWN..RVGTC.IHSAEHGS-YEWK.........
R6MU41_9FIRM/2-55                  .....d-FYKYKCPVCNKQFKEG....DDIVVCP.ECGTPHHRECYE..QEEHC.FYQDKHSQNFSFE.........
A3ZZM9_9PLAN/216-265               ....nt--MRTICNACGDVVKED....--GVACN.DCGAIYHRRCWD..PKVGC.VLYSCEG------ttat.....
R5YDV8_9FIRM/3-54                  ......DYTGKVCPYCKTAFKPD....DKIVICS.ECDMPHHKDCWI..ENQGC.TTFGC--------lgties...
E6UEW2_RUMA7/3-56                  ......NYTGSKCICCGKRFTDE....DDIVVCP.DCGTPYHRSCYV..ENGKC.INSELHDKNIGW-m........
X1BFT7_9ZZZZ/27-77                 ..devf----NSCPVCNFIFEEG....QEILMCD.HCKTLYHEKCFKdlRNNQC.K------------ncgvklh..
D2R359_PIRSD/219-268               .....d--VKTACPVCSDELSGA....--LVQCT.ACKTSHHRDCWS..YFGSC.-ATYGCGSKRC--rn.......
R5GQ20_9FIRM/3-56                  .....r-FDNKLCPICRRPLNDK....SDVVVCP.VCGTPHHRACYM..AAGHC.GVESYHAQGFEWK.........
R6EIU8_9FIRM/2-59                  ......NKFEDICPICGQEIAKEaverGDAVICP.DCGTSYHKACWE..KAGGC.VTFACPSKPKV--qt.......
M1MJV2_9CLOT/3-54                  ......NYIGKICPYCKDEFKEN....DEVISCS.ACEMPHHKECWT..QNQGC.TTFGC--------tgiite...
R6QRD2_9CLOT/2-55                  ......DYTGKKCPICSEKFKAD....DDIVVCP.KCGAPYHRSCYE..KEGRC.IFLDLHRSNEAWK.........
R7MRY6_9FIRM/2-55                  ......NYIGEKCICCNKEFQQG....DDVVVCP.ECGTPYHRDCYK..QNGAC.INNELHEKGESWQ.........
U2DGQ1_CLOS4/3-56                  .....s-YKGELCPVCHKAFADG....DQIVVCP.ECGTPHHRDCYF..QLGHC.ANAERHGEDFAWQ.........
R6P286_9CLOT/3-56                  ......DYTGVPCPICGKAFHEG....DDIVVCP.ICGTPYHRACYE..KEGRC.LFEDKHKEGYVF-h........
R6CMF0_9FIRM/3-56                  ......KYIGAKCSVCGEMFKDG....DDIVVCP.DCGTPYHRACWD..KNGEC.INHELHESGMSW-s........
B0PF21_9FIRM/17-70                 ......NYTGARCPVCNKRFTDN....DDIVVCP.VCGAPHHRECYS..RLGHC.ALAELHIDGHTWQ.........
D4L8K9_9FIRM/2-55                  .....e-FTEYKCPVCDKQFKKG....DDVVVCP.ECGAPHHRECYE..KEGHC.HFADKHGADFSFE.........
M1MYV7_9CLOT/2-53                  ......DFTGKICPYCKGEFKED....DEIVLCS.ICEMPHHKECWV..ENQGC.TTFGCT-------gtimg....
R7A710_9FIRM/2-55                  ......DYTNKLCTKCGKPFQPE....DDVVVCP.ECGSPYHRACWE..EAGGC.INTALHQSGGSWQ.........
J1H3N7_9CLOT/2-55                  ......KYTGIKCPVCGIPFQAD....DDIVVCP.DCGAPYHRHCYE..KEGKC.LFSDTHNTGTYW-t........
R5LJ64_9FIRM/3-56                  .....r-FENKLCPVCRRPFTEN....DDIVVCP.VCGTPHHRACYN..EKGGC.GVEEWHASGFVWE.........
R6DEQ5_9CLOT/4-58                  ......NYKGVSCPVCGQEFKEG....DDIVVCP.ECGAPHHRSCYK..QLGHCaLQQELHEKGMEWK.........
C0E893_9CLOT/3-56                  ......NFIGEVCPICKQKFKSG....DDIVVCP.ECGAPHHRSCYL..EHGAC.AYHDRHAEGFT--vs.......
L0DB65_SINAD/226-274               ...gpp-----ICKVCGEAIEGP....--RVFCA.ICRTPHHRDCWE..YVGTC.SIYGCHGKHS---vs.......
B5IDG2_ACIB4/1537-1587             ......NKEKVKCTLCRGTILPG....MDIVICD.TCGAVYHLPCAK..RAGKC.---LKCGTPFNF-e........
R5MJ60_9FIRM/2-55                  ......DYRGQHCPICGKEFCDG....DDIVVCP.ECGTPYHRECYK..TAGHC.VNEERHGESFEWK.........
R5Y669_9FIRM/2-55                  ......NYTGKICDGCREPFKDG....DDIVVCP.ICGTPQHRSCYE..KNHKC.VNEYLHSTDFTW-t........
R5L268_9CLOT/3-56                  .....l-YENQKCPVCGVAFKSG....DDIVTCP.ECGTPHHRQCYE..KVGKC.ANAELHRSGFVY-n........
R6Q9U7_9FIRM/3-56                  ......KYYGCPCEGCGQPLTLR....DDIVVCP.DCGAPYHRTCYE..KLGRC.IHSPAHAAGYEWK.........
R6RL90_9FIRM/4-56                  .....q-FKNEKCAACGMKFFDD....EDIVVCP.ECGTPYHRECWN..RVGTC.IHSAEHGS-YEWK.........
K6UBZ4_9CLOT/2-54                  .....s-YVGKVCPYCKSEFKED....DEVVICS.VCEMPHHKECWI..ENKAC.TTFGCT-------gtimgt...
W0U939_9FIRM/3-56                  ......NYTGKKCFSCGEVFKDG....DDIVVCP.ECGTPYHRECYL..KEGKC.INDALHESGQSWE.........
Q0W5A9_UNCMA/33-84                 ..ades----GRCDECGLKVKKD....-DATVCP.ACTATYHRWCVT..ECNRC.-NTPLNS------deaeer...
K6TYA4_9CLOT/2-54                  ......DFTGKICPYCKSEFKED....DDVVICS.VCEMPHHKECWS..ENKAC.STFGCTGTNM---sa.......
R5XLT4_9FIRM/3-56                  .....l-YDNQKCPVCGELFKEG....DDVVTCP.ICGTPHHRSCYK..KLGTC.ANESLHLKGFVY-n........
W7V2Y3_RUMFL/2-55                  ......DYIGEKCPVCEKIFTAD....DDIVVCP.DCGTPHHRSCYA..AEKKC.ANEEYHSTGRKWE.........
D4LCL0_RUMC1/2-55                  ......DYTNKLCSKCGKPFRPE....DDVVVCP.ECGSPYHRACWE..EAGGC.INTALHQSGGSWQ.........
E9SD51_RUMAL/3-56                  ......KYTGSKCICCGERFADG....DDIVVCP.ECGTPYHRECYI..KEGKC.INTSLHEKNVSW-l........
G0N885_CAEBE/210-249               ...dnp---EMNCYICRNDYENG....DQVLICK.TCKKPVHRSCWM..K----.-------------wla......
R6NKW4_9CLOT/2-55                  ......KYNGLPCPVCGRIMTDD....DDIVVCP.ECATPQHRECWM..KTGHC.VNEDKHSSGYVW-a........
K1T397_9ZZZZ/1-39                  .....f---------------DD....EDIVVCP.ECGAPYHRECWN..RVGTC.IHSAEHGS-YEWK.........
D2R360_PIRSD/217-265               ....id---GARCVVCGETLET-....-DIVSCV.KCKTPYHRDCWE..YAGAC.STFGCG-------etrav....
R5UYS9_9FIRM/3-56                  ......DYTGQSCFVCQKPFEPE....DDVVVCP.ECGTPYHRACWQ..HYGHC.INVHLHENGGSWK.........
R7KZN4_9FIRM/3-56                  ......NYTGYECKSCGKKFTDD....DDIVVCP.ECGTPYHRDCYK..KEGRC.INDELHSKHMSWK.........
D4JWG4_9FIRM/4-56                  .....q-FKNEKCAACGMKFFDD....EDIVVCP.ECGAPYHRECWN..RVGTC.IHSAEHGS-YEWK.........
R7NJ19_9FIRM/2-55                  ......DYIGFRCPVCDKNFHAD....DDVVVCP.VCGTPHHRKCYE..ELGHC.YNEDKHSEGYDFE.........
R6DV58_9FIRM/2-55                  ......NYTGKICDGCREPLKEG....DDIVVCP.ICGTPQHRSCYE..KNNKC.VNEYLHSTGFTW-t........
R5AAE6_9CLOT/3-56                  ......DYTGIKCPVCGVPFRSG....DDIVVCP.QCGAPYHRACYQ..EKGKC.IFDDLHQEDKAWE.........
D4KCM5_9FIRM/3-56                  ......KYYGCPCEGCGKPLTLQ....DDIVVCP.DCGAPYHRTCYE..KMGLC.IHAPAHGAGYEWK.........
U2KMF3_9FIRM/4-56                  .....h--TGEKCIVCGQVFTDA....DDVVVCP.ECGTPYHRACWQ..KNGAC.INLPLHESGKSWE.........
L0HJL0_ACIS0/1535-1585             ......NKEKVKCTLCRGTILPG....LDIVVCD.NCGAVYHLPCAK..RVGKC.---LKCGTPFNF-e........
K2SDZ0_MACPH/329-377               ....kt--TDDECPICQSSMATNe..lADLVWCKaQCGTNFHRECWT..M----.-------------wertrrssr
R6IX88_9FIRM/2-55                  ....dl--NGQKCPACGRNFDHD....DDIVVCP.VCGTPQHRACWD..ERGEC.VNASRHAEGYVWQ.........
R6Q9T1_9FIRM/3-56                  .....s-YKNEKCPVCNQEFKDG....DDIVTCP.VCGTPHHRECYK..KIGHC.FNEDKHAEGYEFK.........
G0PIH3_CAEBE/700-739               ....nd--PERNCYICKDDFENG....DQVLICK.TCKKPVHRSCWM..K----.-------------wla......
H8I925_METCZ/22-71                 .kkdea----GRCDECGLKVKKD....-DAVVCP.MCSAVYHRWCAT..ECNVC.K------------tpfderle.
B5IDB3_ACIB4/1537-1587             ......NKEKVKCTLCRGTILPG....MDIVICD.TCGAVYHLPCAK..RAGKC.---LKCGTPFNF-e........
R5XXX1_9FIRM/3-56                  .....e-YVGKVCPYCKTEIREG....DDVKACH.ECGIPHHAACWE..ENKGC.TTFGCKQQHYE--eq.......
#=GC seq_cons                      .......apsppCssCsptFpcs....DDIVVCP.pCGsPaHRpCap..ctGpC.hptshHtpshta..........
//
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