GenomeNet

Database: Pfam
Entry: Prok-RING_1
LinkDB: Prok-RING_1
Original site: Prok-RING_1 
#=GF ID   Prok-RING_1
#=GF AC   PF14446.4
#=GF DE   Prokaryotic RING finger family 1
#=GF AU   Burroughs AM, Iyer LM, Aravind L
#=GF SE   Manual
#=GF GA   29.10 29.10;
#=GF TC   29.10 29.20;
#=GF NC   28.80 29.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   21547297
#=GF RT   Functional diversification of the RING finger and other
#=GF RT   binuclear treble clef domains in prokaryotes and the early
#=GF RT   evolution of the ubiquitin system.
#=GF RA   Burroughs AM, Iyer LM, Aravind L;
#=GF RL   Mol Biosyst. 2011;7:2261-2277.
#=GF CC   RING finger family found sporadically in bacteria and archaea,
#=GF CC   and  associated in gene neighborhoods with other components of
#=GF CC   the  ubiquitin-based signaling and degradation system, including
#=GF CC    ubiquitin, the E1 and E2 proteins and the JAB-like
#=GF CC   metallopeptidase.  The bacterial versions contain transmembrane
#=GF CC   helices [1].
#=GF SQ   54
#=GS M5FYV8_DACSP/235-279    AC M5FYV8.1
#=GS Q0W5A9_METAR/33-84      AC Q0W5A9.1
#=GS K6TYA4_9CLOT/2-54       AC K6TYA4.1
#=GS R5XLT4_9FIRM/3-56       AC R5XLT4.1
#=GS L7UF71_MYXSD/11-62      AC L7UF71.1
#=GS R6T2N4_9FIRM/3-56       AC R6T2N4.1
#=GS F8DAY1_HALXS/20-54      AC F8DAY1.1
#=GS D4LCL0_RUMC1/2-55       AC D4LCL0.1
#=GS R6GQX3_9CLOT/3-57       AC R6GQX3.1
#=GS E9SD51_RUMAL/3-56       AC E9SD51.1
#=GS G0N885_CAEBE/210-249    AC G0N885.1
#=GS R7F8M1_9FIRM/4-57       AC R7F8M1.1
#=GS R6UCX1_9CLOT/2-55       AC R6UCX1.1
#=GS W1PIR8_AMBTC/145-184    AC W1PIR8.1
#=GS R6NKW4_9CLOT/2-55       AC R6NKW4.1
#=GS R6Y3H6_9FIRM/3-56       AC R6Y3H6.1
#=GS G9RVU5_9FIRM/3-56       AC G9RVU5.1
#=GS G0P7C0_CAEBE/640-679    AC G0P7C0.1
#=GS D2R360_PIRSD/217-265    AC D2R360.1
#=GS R5DT60_9FIRM/2-55       AC R5DT60.1
#=GS D4K3Q4_9FIRM/3-56       AC D4K3Q4.1
#=GS R6MU41_9FIRM/2-55       AC R6MU41.1
#=GS A3ZZM9_9PLAN/216-265    AC A3ZZM9.1
#=GS E6UEW2_RUMA7/3-56       AC E6UEW2.1
#=GS R7KZN4_9FIRM/3-56       AC R7KZN4.1
#=GS R5UYS9_9FIRM/3-56       AC R5UYS9.1
#=GS D4JWG4_9FIRM/4-56       AC D4JWG4.1
#=GS D2R359_PIRSD/219-268    AC D2R359.1
#=GS R5GQ20_9FIRM/3-56       AC R5GQ20.1
#=GS R6QRD2_9CLOT/2-55       AC R6QRD2.1
#=GS R7MRY6_9FIRM/2-55       AC R7MRY6.1
#=GS R6EIU8_9FIRM/2-59       AC R6EIU8.1
#=GS R7NJ19_9FIRM/2-55       AC R7NJ19.1
#=GS M1MJV2_9CLOT/3-54       AC M1MJV2.1
#=GS D4KCM5_9FIRM/3-56       AC D4KCM5.1
#=GS R6DV58_9FIRM/2-55       AC R6DV58.1
#=GS R5AAE6_9CLOT/3-56       AC R5AAE6.1
#=GS R6P286_9CLOT/3-56       AC R6P286.1
#=GS R6CMF0_9FIRM/3-56       AC R6CMF0.1
#=GS B0PF21_9FIRM/17-70      AC B0PF21.1
#=GS K2SDZ0_MACPH/329-377    AC K2SDZ0.1
#=GS M1MYV7_9CLOT/2-53       AC M1MYV7.1
#=GS K6UBZ4_9CLOT/2-53       AC K6UBZ4.1
#=GS J1H3N7_9CLOT/2-55       AC J1H3N7.1
#=GS R6DEQ5_9CLOT/4-58       AC R6DEQ5.1
#=GS R6IX88_9FIRM/2-55       AC R6IX88.1
#=GS C0E893_9FIRM/3-56       AC C0E893.1
#=GS L0DB65_SINAD/226-274    AC L0DB65.1
#=GS R5MJ60_9FIRM/2-55       AC R5MJ60.1
#=GS R6Q9T1_9FIRM/3-56       AC R6Q9T1.1
#=GS R5L268_9CLOT/3-56       AC R5L268.1
#=GS G0PIH3_CAEBE/700-739    AC G0PIH3.1
#=GS R6Q9U7_9FIRM/3-56       AC R6Q9U7.1
#=GS B5IDB3_ACIB4/1537-1587  AC B5IDB3.1
M5FYV8_DACSP/235-279               ....pq--EGNDCPICYESMPPGe..eEGLVFCP.ACGNGLHRGCFEQWGK-.-------------tpn......
Q0W5A9_METAR/33-84                 ..ades----GRCDECGLKVKKD....-DATVCP.ACTATYHRWCVTECNRC.-NTPLNS------deaeer...
K6TYA4_9CLOT/2-54                  ......DFTGKICPYCKSEFKED....DDVVICS.VCEMPHHKECWSENKAC.STFGCTGTNM---sa.......
R5XLT4_9FIRM/3-56                  .....l-YDNQKCPVCGELFKEG....DDVVTCP.ICGTPHHRSCYKKLGTC.ANESLHLKGFVY-n........
L7UF71_MYXSD/11-62                 ....af--AGNTCGICQTGIEVG....EEVGTCP.ACQAPFHAECWAENGGC.AQYGC--------ahmpgt...
R6T2N4_9FIRM/3-56                  ......NYTGKKCFSCGEVFKDG....DDIVVCP.ECGTPYHRECYLKEGKC.INDALHESGQSWE.........
F8DAY1_HALXS/20-54                 .....l--EGRSCPSCGGELERDvykdKDAVVCA.ECGTP------------.-------------raq......
D4LCL0_RUMC1/2-55                  ......DYTNKLCSKCGKPFRPE....DDVVVCP.ECGSPYHRACWEEAGGC.INTALHQSGGSWQ.........
R6GQX3_9CLOT/3-57                  nyrkfg-----ECPVCNVECKID....EDIVVCP.ECGAPYHRECYNSVGQC.VYKEKHSQGFSY-t........
E9SD51_RUMAL/3-56                  ......KYTGSKCICCGERFADG....DDIVVCP.ECGTPYHRECYIKEGKC.INTSLHEKNVSW-l........
G0N885_CAEBE/210-249               ...dnp---EMNCYICRNDYENG....DQVLICK.TCKKPVHRSCWMK----.-------------wla......
R7F8M1_9FIRM/4-57                  ....rh--VGQECFGCHQKLQED....DDIVVCP.ECGTPYHRACWQKTGHC.LNAPLHASGKSWD.........
R6UCX1_9CLOT/2-55                  ......NYYNQKCPGCHKAFNKD....DDIVVCP.VCGTPQHRECYEKENRC.VNYDKHSKTYEWN.........
W1PIR8_AMBTC/145-184               ...grg----GLCPVCFEGMDDE....GEVVVCG.RCRNGLHRECWGE----.-------------wkrr.....
R6NKW4_9CLOT/2-55                  ......KYNGLPCPVCGRIMTDD....DDIVVCP.ECATPQHRECWMKTGHC.VNEDKHSSGYVW-a........
R6Y3H6_9FIRM/3-56                  ......DYTGIKCPVCGVPFRSG....DDIVVCP.ECGAPYHRACYQEKGAC.IFDDLHKEGKEWK.........
G9RVU5_9FIRM/3-56                  ......DYKGCKCASCHKVLKEG....DDIVICP.ECGAPYHRECYAAEGRC.VFSAKHGKGFEY-v........
G0P7C0_CAEBE/640-679               ....nd--PERNCYICKDDFENG....DHVLICK.TCKKPVHRSCWMK----.-------------wla......
D2R360_PIRSD/217-265               ....id---GARCVVCGETLET-....-DIVSCV.KCKTPYHRDCWEYAGAC.STFGCG-------etrav....
R5DT60_9FIRM/2-55                  .....e-FTEYKCPVCDKQFKKG....DDIVVCP.ECGAPHHRECYEKEGHC.HFADKHGADFSFE.........
D4K3Q4_9FIRM/3-56                  ......KYYGCPCEGCGKPLTLQ....DDIVVCP.DCGAPYHRDCYEKLGQC.IHRPAHAAGCEWK.........
R6MU41_9FIRM/2-55                  .....d-FYKYKCPVCNKQFKEG....DDIVVCP.ECGTPHHRECYEQEEHC.FYQDKHSQNFSFE.........
A3ZZM9_9PLAN/216-265               ....nt--MRTICNACGDVVKED....--GVACN.DCGAIYHRRCWDPKVGC.VLYSCEG------ttat.....
E6UEW2_RUMA7/3-56                  ......NYTGSKCICCGKRFTDE....DDIVVCP.DCGTPYHRSCYVENGKC.INSELHDKNIGW-m........
R7KZN4_9FIRM/3-56                  ......NYTGYECKSCGKKFTDD....DDIVVCP.ECGTPYHRDCYKKEGRC.INDELHSKHMSWK.........
R5UYS9_9FIRM/3-56                  ......DYTGQSCFVCQKPFEPE....DDVVVCP.ECGTPYHRACWQHYGHC.INVHLHENGGSWK.........
D4JWG4_9FIRM/4-56                  .....q-FKNEKCAACGMKFFDD....EDIVVCP.ECGAPYHRECWNRVGTC.IHSAEHGS-YEWK.........
D2R359_PIRSD/219-268               .....d--VKTACPVCSDELSGA....--LVQCT.ACKTSHHRDCWSYFGSC.-ATYGCGSKRC--rn.......
R5GQ20_9FIRM/3-56                  .....r-FDNKLCPICRRPLNDK....SDVVVCP.VCGTPHHRACYMAAGHC.GVESYHAQGFEWK.........
R6QRD2_9CLOT/2-55                  ......DYTGKKCPICSEKFKAD....DDIVVCP.KCGAPYHRSCYEKEGRC.IFLDLHRSNEAWK.........
R7MRY6_9FIRM/2-55                  ......NYIGEKCICCNKEFQQG....DDVVVCP.ECGTPYHRDCYKQNGAC.INNELHEKGESWQ.........
R6EIU8_9FIRM/2-59                  ......NKFEDICPICGQEIAKEaverGDAVICP.DCGTSYHKACWEKAGGC.VTFACPSKPKV--qt.......
R7NJ19_9FIRM/2-55                  ......DYIGFRCPVCDKNFHAD....DDVVVCP.VCGTPHHRKCYEELGHC.YNEDKHSEGYDFE.........
M1MJV2_9CLOT/3-54                  ......NYIGKICPYCKDEFKEN....DEVISCS.ACEMPHHKECWTQNQGC.TTFGC--------tgiite...
D4KCM5_9FIRM/3-56                  ......KYYGCPCEGCGKPLTLQ....DDIVVCP.DCGAPYHRTCYEKMGLC.IHAPAHGAGYEWK.........
R6DV58_9FIRM/2-55                  ......NYTGKICDGCREPLKEG....DDIVVCP.ICGTPQHRSCYEKNNKC.VNEYLHSTGFTW-t........
R5AAE6_9CLOT/3-56                  ......DYTGIKCPVCGVPFRSG....DDIVVCP.QCGAPYHRACYQEKGKC.IFDDLHQEDKAWE.........
R6P286_9CLOT/3-56                  ......DYTGVPCPICGKAFHEG....DDIVVCP.ICGTPYHRACYEKEGRC.LFEDKHKEGYVF-h........
R6CMF0_9FIRM/3-56                  ......KYIGAKCSVCGEMFKDG....DDIVVCP.DCGTPYHRACWDKNGEC.INHELHESGMSW-s........
B0PF21_9FIRM/17-70                 ......NYTGARCPVCNKRFTDN....DDIVVCP.VCGAPHHRECYSRLGHC.ALAELHIDGHTWQ.........
K2SDZ0_MACPH/329-377               ....kt--TDDECPICQSSMATNe..lADLVWCKaQCGTNFHRECWTM----.-------------wertrrssr
M1MYV7_9CLOT/2-53                  ......DFTGKICPYCKGEFKED....DEIVLCS.ICEMPHHKECWVENQGC.TTFGCT-------gtimg....
K6UBZ4_9CLOT/2-53                  .....s-YVGKVCPYCKSEFKED....DEVVICS.VCEMPHHKECWIENKAC.TTFGCT-------gtimg....
J1H3N7_9CLOT/2-55                  ......KYTGIKCPVCGIPFQAD....DDIVVCP.DCGAPYHRHCYEKEGKC.LFSDTHNTGTYW-t........
R6DEQ5_9CLOT/4-58                  ......NYKGVSCPVCGQEFKEG....DDIVVCP.ECGAPHHRSCYKQLGHCaLQQELHEKGMEWK.........
R6IX88_9FIRM/2-55                  ....dl--NGQKCPACGRNFDHD....DDIVVCP.VCGTPQHRACWDERGEC.VNASRHAEGYVWQ.........
C0E893_9FIRM/3-56                  ......NFIGEVCPICKQKFKSG....DDIVVCP.ECGAPHHRSCYLEHGAC.AYHDRHAEGFT--vs.......
L0DB65_SINAD/226-274               ...gpp-----ICKVCGEAIEGP....--RVFCA.ICRTPHHRDCWEYVGTC.SIYGCHGKHS---vs.......
R5MJ60_9FIRM/2-55                  ......DYRGQHCPICGKEFCDG....DDIVVCP.ECGTPYHRECYKTAGHC.VNEERHGESFEWK.........
R6Q9T1_9FIRM/3-56                  .....s-YKNEKCPVCNQEFKDG....DDIVTCP.VCGTPHHRECYKKIGHC.FNEDKHAEGYEFK.........
R5L268_9CLOT/3-56                  .....l-YENQKCPVCGVAFKSG....DDIVTCP.ECGTPHHRQCYEKVGKC.ANAELHRSGFVY-n........
G0PIH3_CAEBE/700-739               ....nd--PERNCYICKDDFENG....DQVLICK.TCKKPVHRSCWMK----.-------------wla......
R6Q9U7_9FIRM/3-56                  ......KYYGCPCEGCGQPLTLR....DDIVVCP.DCGAPYHRTCYEKLGRC.IHSPAHAAGYEWK.........
B5IDB3_ACIB4/1537-1587             ......NKEKVKCTLCRGTILPG....MDIVICD.TCGAVYHLPCAKRAGKC.---LKCGTPFNF-e........
#=GC seq_cons                      .......ahGppCssCsctacps....DDlVVCP.pCGsPaHRpCapctGpC.h.tshHtpsh.a..........
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