GenomeNet

Database: Pfam
Entry: RESP18
LinkDB: RESP18
Original site: RESP18 
#=GF ID   RESP18
#=GF AC   PF14948.2
#=GF DE   RESP18 domain
#=GF AU   Eberhardt R
#=GF SE   Jackhmmer:Q5W5W9
#=GF GA   25.00 25.00;
#=GF TC   27.80 26.00;
#=GF NC   23.90 23.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   21104147
#=GF RT   Requirement of regulated endocrine-specific protein-18 for
#=GF RT   development and expression of regulated endocrine-specific
#=GF RT   protein-18 isoform c in mice.
#=GF RA   Liang M, Yang JL, Bian MJ, Liu J, Hong XQ, Wang YC, Huang YF, Gu
#=GF RA   SP, Yu M, Huang F, Fei J;
#=GF RL   Mol Biol Rep. 2011;38:2557-2562.
#=GF RN   [2]
#=GF RM   17951542
#=GF RT   RESP18, a homolog of the luminal domain IA-2, is found in dense
#=GF RT   core vesicles in  pancreatic islet cells and is induced by high
#=GF RT   glucose.
#=GF RA   Zhang G, Hirai H, Cai T, Miura J, Yu P, Huang H, Schiller MR,
#=GF RA   Swaim WD, Leapman RD, Notkins AL;
#=GF RL   J Endocrinol. 2007;195:313-321.
#=GF DR   INTERPRO; IPR029403;
#=GF CC   This domain is found in the glucocorticoid-responsive protein
#=GF CC   regulated endocrine-specific protein 18 (RESP18) and in the
#=GF CC   N-terminal extracellular region of receptor-type
#=GF CC   tyrosine-protein phosphatases containing the protein-tyrosine
#=GF CC   phosphatase receptor IA-2 domain (Pfam:PF11548) [1,2].
#=GF SQ   156
#=GS W5QFY6_SHEEP/37-142   AC W5QFY6.1
#=GS F1R8X1_DANRE/47-121   AC F1R8X1.1
#=GS A8K604_HUMAN/60-160   AC A8K604.1
#=GS F7A9S9_XENTR/49-163   AC F7A9S9.1
#=GS PTPRN_HUMAN/60-160    AC Q16849.1
#=GS S7NP26_MYOBR/40-136   AC S7NP26.1
#=GS PTPRN_BOVIN/60-160    AC P56722.1
#=GS A3KPJ4_DANRE/70-170   AC A3KPJ4.2
#=GS F7ES81_MACMU/37-137   AC F7ES81.1
#=GS E9QB40_DANRE/47-153   AC E9QB40.1
#=GS G5AKJ5_HETGA/37-139   AC G5AKJ5.1
#=GS H2UFW5_TAKRU/27-98    AC H2UFW5.1
#=GS H2PP66_PONAB/21-106   AC H2PP66.1
#=GS B3DJH4_DANRE/47-147   AC B3DJH4.1
#=GS K7C882_PANTR/60-160   AC K7C882.1
#=GS H9FXU6_MACMU/59-140   AC H9FXU6.1
#=GS U3DVH3_CALJA/60-160   AC U3DVH3.1
#=GS H2P8P3_PONAB/37-138   AC H2P8P3.1
#=GS B0CM60_PAPAN/60-160   AC B0CM60.1
#=GS F1QIB8_DANRE/50-150   AC F1QIB8.1
#=GS U3ELC9_CALJA/60-160   AC U3ELC9.1
#=GS M3W8R9_FELCA/12-102   AC M3W8R9.1
#=GS W5QFR7_SHEEP/64-169   AC W5QFR7.1
#=GS Q6NVE2_MOUSE/67-162   AC Q6NVE2.1
#=GS G1MEE8_AILME/60-159   AC G1MEE8.1
#=GS W5KE42_ASTMX/47-136   AC W5KE42.1
#=GS I3K2I3_ORENI/49-139   AC I3K2I3.1
#=GS W5N3T4_LEPOC/48-132   AC W5N3T4.1
#=GS M3YEH3_MUSPF/2-89     AC M3YEH3.1
#=GS B4DGA1_HUMAN/60-157   AC B4DGA1.1
#=GS Q4RQS0_TETNG/18-119   AC Q4RQS0.1
#=GS F1SR78_PIG/60-159     AC F1SR78.2
#=GS D2HQQ8_AILME/22-121   AC D2HQQ8.1
#=GS G1KP25_ANOCA/45-128   AC G1KP25.2
#=GS H2P8P2_PONAB/60-160   AC H2P8P2.1
#=GS A6MDD2_MOUSE/63-158   AC A6MDD2.1
#=GS F6US37_HORSE/37-139   AC F6US37.1
#=GS PTPR2_HUMAN/59-142    AC Q92932.2
#=GS M7AWL5_CHEMY/559-675  AC M7AWL5.1
#=GS W5KPX0_ASTMX/22-101   AC W5KPX0.1
#=GS H0XDK2_OTOGA/37-140   AC H0XDK2.1
#=GS F6R0M5_CALJA/60-157   AC F6R0M5.1
#=GS F7E5U0_CALJA/60-160   AC F7E5U0.1
#=GS H9FXU7_MACMU/59-140   AC H9FXU7.1
#=GS K7EUG8_PONAB/60-160   AC K7EUG8.1
#=GS G3WJ01_SARHA/22-113   AC G3WJ01.1
#=GS U3D4X3_CALJA/60-153   AC U3D4X3.1
#=GS M4A8F6_XIPMA/48-129   AC M4A8F6.1
#=GS Q9Y4I9_HUMAN/59-142   AC Q9Y4I9.1
#=GS I3K2I4_ORENI/47-137   AC I3K2I4.1
#=GS H0Z6G4_TAEGU/22-110   AC H0Z6G4.1
#=GS W5MXC4_LEPOC/28-113   AC W5MXC4.1
#=GS H0V3J5_CAVPO/60-152   AC H0V3J5.1
#=GS U3DU84_CALJA/59-152   AC U3DU84.1
#=GS E6ZJ13_DICLA/4-95     AC E6ZJ13.1
#=GS F7H047_MACMU/60-145   AC F7H047.1
#=GS G3I619_CRIGR/12-114   AC G3I619.1
#=GS X1WH84_DANRE/47-137   AC X1WH84.1
#=GS RES18_HUMAN/37-138    AC Q5W5W9.1
#=GS U3CT49_CALJA/59-152   AC U3CT49.1
#=GS V8P9P5_OPHHA/68-141   AC V8P9P5.1
#=GS U3DMN1_CALJA/60-153   AC U3DMN1.1
#=GS Q5DTQ3_MOUSE/76-171   AC Q5DTQ3.1
#=GS F6TGE3_CALJA/72-173   AC F6TGE3.1
#=GS R4GHU3_CHICK/76-162   AC R4GHU3.1
#=GS I3K2I5_ORENI/22-112   AC I3K2I5.1
#=GS I3MHI4_SPETR/61-156   AC I3MHI4.1
#=GS M3YYW0_MUSPF/60-160   AC M3YYW0.1
#=GS M4ANC3_XIPMA/47-137   AC M4ANC3.1
#=GS L5LWZ9_MYODS/33-101   AC L5LWZ9.1
#=GS D2HQQ9_AILME/2-88     AC D2HQQ9.1
#=GS PTPR2_MACNE/57-139    AC O02695.1
#=GS B0KWI8_CALJA/1-70     AC B0KWI8.1
#=GS F7ES91_MACMU/37-141   AC F7ES91.1
#=GS Q5R982_PONAB/60-160   AC Q5R982.1
#=GS C9JR27_HUMAN/27-128   AC C9JR27.1
#=GS G3T308_LOXAF/60-164   AC G3T308.1
#=GS C9JJL7_HUMAN/1-74     AC C9JJL7.2
#=GS J9P792_CANFA/60-160   AC J9P792.1
#=GS PTPR2_MOUSE/58-140    AC P80560.2
#=GS G3SFN6_GORGO/74-161   AC G3SFN6.1
#=GS M3ZJM2_XIPMA/50-162   AC M3ZJM2.1
#=GS K9INK6_DESRO/56-148   AC K9INK6.1
#=GS H2QJG8_PANTR/79-166   AC H2QJG8.1
#=GS RES18_MOUSE/37-140    AC P47939.1
#=GS M3WER6_FELCA/60-160   AC M3WER6.1
#=GS Q6GPA6_XENLA/49-169   AC Q6GPA6.1
#=GS K6ZLK2_PANTR/60-160   AC K6ZLK2.1
#=GS C9JK57_HUMAN/1-74     AC C9JK57.1
#=GS RES18_RAT/37-140      AC P47940.1
#=GS B3DJG5_DANRE/47-121   AC B3DJG5.1
#=GS G7N8Z9_MACMU/37-137   AC G7N8Z9.1
#=GS H2UFW4_TAKRU/27-98    AC H2UFW4.1
#=GS B2GU79_XENTR/49-169   AC B2GU79.1
#=GS G1RDV0_NOMLE/50-150   AC G1RDV0.1
#=GS L8Y330_TUPCH/60-132   AC L8Y330.1
#=GS F1PMD6_CANFA/60-160   AC F1PMD6.1
#=GS F6U2N5_CALJA/65-164   AC F6U2N5.1
#=GS U6DLE8_NEOVI/59-159   AC U6DLE8.1
#=GS G5AKJ6_HETGA/60-155   AC G5AKJ6.1
#=GS F7D9P9_HORSE/64-163   AC F7D9P9.1
#=GS G3HTT8_CRIGR/3-85     AC G3HTT8.1
#=GS H0VV96_CAVPO/19-106   AC H0VV96.1
#=GS L8IWF8_9CETA/37-139   AC L8IWF8.1
#=GS I3J8R2_ORENI/47-147   AC I3J8R2.1
#=GS H2R644_PANTR/60-160   AC H2R644.1
#=GS H3DG99_TETNG/22-108   AC H3DG99.1
#=GS Q925J7_MOUSE/1-53     AC Q925J7.1
#=GS PTPR2_RAT/58-145      AC Q63475.1
#=GS H2UFW6_TAKRU/27-98    AC H2UFW6.1
#=GS G5C8S2_HETGA/42-128   AC G5C8S2.1
#=GS L5L2A3_PTEAL/60-156   AC L5L2A3.1
#=GS F6RCL7_MONDO/54-153   AC F6RCL7.2
#=GS RES18_BOVIN/37-139    AC A0JNL8.1
#=GS F1SR77_PIG/37-139     AC F1SR77.1
#=GS T1DHQ2_CROHD/64-144   AC T1DHQ2.1
#=GS Q8BT93_MOUSE/37-142   AC Q8BT93.1
#=GS K7E663_MONDO/4-84     AC K7E663.1
#=GS U3FVJ4_CALJA/60-160   AC U3FVJ4.1
#=GS PTPRN_RAT/66-163      AC Q63259.2
#=GS I2CY08_MACMU/60-160   AC I2CY08.1
#=GS G7PK47_MACFA/37-137   AC G7PK47.1
#=GS W5MXD0_LEPOC/48-133   AC W5MXD0.1
#=GS G7PK46_MACFA/25-125   AC G7PK46.1
#=GS C9JCQ0_HUMAN/1-75     AC C9JCQ0.1
#=GS E1BYQ1_CHICK/62-157   AC E1BYQ1.2
#=GS B9W0B0_MOUSE/37-120   AC B9W0B0.1
#=GS W5K3K7_ASTMX/22-91    AC W5K3K7.1
#=GS G3R874_GORGO/73-173   AC G3R874.1
#=GS G1U816_RABIT/60-160   AC G1U816.2
#=GS G3INC6_CRIGR/1-65     AC G3INC6.1
#=GS C0HAC4_SALSA/47-138   AC C0HAC4.1
#=GS F6PIZ6_CALJA/60-160   AC F6PIZ6.1
#=GS F6TF72_CALJA/33-132   AC F6TF72.1
#=GS A3KN68_MOUSE/58-128   AC A3KN68.1
#=GS Q925J6_MOUSE/1-53     AC Q925J6.1
#=GS G3QNU1_GORGO/79-166   AC G3QNU1.1
#=GS G7N8Z8_MACMU/60-160   AC G7N8Z8.1
#=GS G1PAU4_MYOLU/66-162   AC G1PAU4.1
#=GS G1MEF3_AILME/37-140   AC G1MEF3.1
#=GS A8MW94_HUMAN/1-56     AC A8MW94.1
#=GS U3JNT8_FICAL/1-49     AC U3JNT8.1
#=GS L8IW25_9CETA/69-169   AC L8IW25.1
#=GS G1T8W0_RABIT/37-139   AC G1T8W0.1
#=GS H0XDJ7_OTOGA/60-156   AC H0XDJ7.1
#=GS I3MHI7_SPETR/37-139   AC I3MHI7.1
#=GS S9Y636_9CETA/457-529  AC S9Y636.1
#=GS Q59FU1_HUMAN/32-132   AC Q59FU1.1
#=GS G3NSZ9_GASAC/22-121   AC G3NSZ9.1
#=GS Q571D4_MOUSE/82-164   AC Q571D4.1
#=GS Q3UU93_MOUSE/58-140   AC Q3UU93.1
#=GS PTPRN_MOUSE/63-158    AC Q60673.2
#=GS H9EW26_MACMU/60-160   AC H9EW26.1
#=GS C9J392_HUMAN/1-66     AC C9J392.1
#=GS F7GFM0_CALJA/67-166   AC F7GFM0.1
#=GS F7GWZ3_CALJA/1-70     AC F7GWZ3.1
W5QFY6_SHEEP/37-142              .................GQSQVGVGQLWPLPGFTSPVFKHLQVLLQHIM...PHG...FFWKDDMTQEVMTQKMGHTSK..L.HP.....EDPCVRSG......PAAFPT.KTPGVR........GKQEEKLRLLFPKs..sqSPMVKVNKDQC...............................................
F1R8X1_DANRE/47-121              .................GQCRSSRH-DQVQYQVSVPVLQRLQQVLKELM...LQG...FSWQDEITQQIIAKELSRIPH..T.RT.....QKSQ----......------.------........-------------.....-----------naqppppaakkvy..................................
A8K604_HUMAN/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPK.RPGPAG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
F7A9S9_XENTR/49-163              .................GQCRPRADRDDAPFQVPPGALQQLQGVLRQLT...AKG...FPWKDDMTPRLLAHEMGRIPQ..H.RPl..etLDGLDEDR......SGRTMQ.RLPGMSqms.aprwAGSADKLQYFRPRl...pSPL--------gdtspqkp.......................................
PTPRN_HUMAN/60-160               .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPK.RPGPAG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
S7NP26_MYOBR/40-136              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPHPRDR......SGLVPR.RPGPAE........-------------.....-----------elllqgiptgpapaaphr.............................
PTPRN_BOVIN/60-160               .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPHPRDR......SGLVPR.RPGPAG........-------------.....-----------elllqgiptgsapalqhrlprp.........................
A3KPJ4_DANRE/70-170              .................GQCLRYPGSDVSSFDVSPAAVQRLRSVLQKLA...HRG...YTWQDDITQQVISKELSQLPR..V.SL.....--------......------.------........-------------.....-----------ggfantfphfndnsrklkaqkeaasrtlqrflqgflpsdvss.....
F7ES81_MACMU/37-137              .................GQDQVGVEQLWPLQGFATPVFQHLQVVFQQIL...PQG...LFWKDDITQDAMIQKMEHTSR..L.HP.....QDPCLKDG......KAVFPT.KTAGSP........LAKVNRDQCFTSK.....-----------vvskvlkqe......................................
E9QB40_DANRE/47-153              ....grceaapltnvyt-------------YDVTPATVQRLRNLLQRLA...HRG...LSWEDDVTQQILSNEFSKLRR..V.SLp...lPEPRPKGY......EIAFGD.RRMKSSs......dAEVKNTLKYLQ--.....-----------hllllpktalhkg..................................
G5AKJ5_HETGA/37-139              .................GQCQAEVAQLWPLQEFTAPFFRHLQVLLHQLV...PQG...LFWKNDIIQDLMTQNMEHMSR..L.HL.....QDPCLKGG......KAIFPA.RTTGVR........GKQEEKLQLLFPT.....SPMPRVNRDQC...............................................
H2UFW5_TAKRU/27-98               .................GQCL-SSKQDKVQYQVSVQVLKRMQEVLKQLM...LQG...LSWQDDITQYILSKELKRVPH..T.--.....--------......------.------........-------------.....-----------srtskssssfpsshsp...............................
H2PP66_PONAB/21-106              .....grcqkvpamdfy------------RYEVSPVALQRLRLALQKLS...GTG...FTWQDDYTQYVMDQELADLPK..T.YL.....RRPE----......-ASS--.------........-------------.....-----------parpskhsvgserkysregg...........................
B3DJH4_DANRE/47-147              .................GQCLRYPGSDVSSFDVSPAAVQRLRSVLQKLA...HRG...YTWQDDITQQVISKELSQLPR..V.SL.....--------......------.------........-------------.....-----------ggfantfphfndnsrklkaqkeaasrtlqrflqgflpsdvss.....
K7C882_PANTR/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPHPRDR......SGLAPK.RPGPAG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
H9FXU6_MACMU/59-140              .....grcqkvpamdfy------------RYEVSPVALQRLRVALQKLS...GTG...FTWQDDYTQYVMDQELADLPK..T.YL.....RHPE----......------.------........-------------.....-----------asgparpskhsigserrys............................
U3DVH3_CALJA/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQSVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RL.....PEPRPRDR......SGLAPR.RPGPTG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
H2P8P3_PONAB/37-138              .................GQDQVGVGQLWPLQGFATPVFQHLQVVLQQII...PQG...LFWKDDITQDAMIQKMEHASR..L.HP.....QDPCLKDG......KAVFPT.KTTESP........LAKVNRDQCFTSK.....-----------vvskvlkqev.....................................
B0CM60_PAPAN/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPR.RPGPAG........-------ELLLQD.....-----------iptgsapasqhrlpqp...............................
F1QIB8_DANRE/50-150              .................GQCLRYPGSDVSSFDVSPAAVQRLRSVLQKLA...HRG...YTWQDDITQQVISKELSQLPR..V.SL.....--------......------.------........-------------.....-----------ggfantfphfndnsrklkaqkeaasrtlqrflqgflpsdvss.....
U3ELC9_CALJA/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQSVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RL.....PEPRPRDR......SGLAPR.RPGPTG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
M3W8R9_FELCA/12-102              .................GRCQKVPAVDTHRYEVSPAVLQHLAATLQKLS...RTG...FTWQDDYTQHVMAQELLNLPS..P.QH.....LDASSTA-......------.------........-------------.....-----------rtskqsvdedrrssleddgglarav......................
W5QFR7_SHEEP/64-169              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPHPRDR......SGLVPR.RPGPAG........-------E-----.....-----------lllqgiptgsapapqhrhlllpaqpp.....................
Q6NVE2_MOUSE/67-162              .................GQCQAGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQHVISQEMERIPR..L.RP.....PEPHPRDR......SGLLPR.KPGPAG........-------ELLTQG.....-----------nptgsspaaqg....................................
G1MEE8_AILME/60-159              .................GQCQVGAGQARPLLQVTSPVLQRLQSVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.HP.....PEPRPRDR......SGLVPR.RPGPAG........-------ELLLQ-.....-----------giptgstpatqhrlpq...............................
W5KE42_ASTMX/47-136              .................GQCRSS-RQDQVQYQVSVPVLQRLQEVLKELM...MQG...FSWQDDITQSIIAKELSRVPH..S.RA.....QTPQPGPS......AQHSPK.KAYS--........-------------.....-----------nskteprtpqsymd.................................
I3K2I3_ORENI/49-139              .................GQCQAPHQEPV-QYQVSVPVLHKLQEVLKDLM...VQG...LNWKDDMTQAIISRELSQVPT..I.ET.....HSKLNEK-......------.------........-------------.....-----------spklssrllgsspqrgqgpedqadpk.....................
W5N3T4_LEPOC/48-132              ...grcqrvpvidvyry--------------EVSPAALQRLRSLLQKLS...QRG...LTWKDDATQQVISKELSKLRK..V.--.....--------......------.------........-------------.....-----------yyrlsetnspdigsnprtpsqnidsekk...................
M3YEH3_MUSPF/2-89                ............dthry--------------EVSPGALQHLTATLQKLS...RTG...FTWQDGYTQRVMAQELSDLPH..A.YPrhldaS---D---......------.------........-------------.....-----------tarslersaekerrsslqeagalaravqryl................
B4DGA1_HUMAN/60-157              .................GQCQVGVGQAWPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPK.RPGPAG........-------ELLLQ-.....-----------diptgsapaaqlls.................................
Q4RQS0_TETNG/18-119              ................g-QCL-SSKQDKVQYQVSVPVLKRMQEVLKQLM...LQG...LSWQDDITQYILSKELKRVPH..TsRA.....SKPSSSSP......SSHSPQ.SQANQR........ERERD-RQLLQ--.....-----------ealslylasaqps..................................
F1SR78_PIG/60-159                .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPPARDR......SGLVPR.RPGPAG........-------E-----.....-----------lllqgiptgsapapqhrlpr...........................
D2HQQ8_AILME/22-121              .................GQCQVGAGQARPLLQVTSPVLQRLQSVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.HP.....PEPRPRDR......SGLVPR.RPGPAG........-------ELLLQ-.....-----------giptgstpatqhrlpq...............................
G1KP25_ANOCA/45-128              .................GQCQESSQQDRPYFQVSAAVLQRLQDVLRHLM...AQG...LSWQDGLTQYVISREMERIPK..L.HL.....STTWESVA......------.------........-------------.....-----------enrlpsmypaprrtslp..............................
H2P8P2_PONAB/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPR.RPGPAG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
A6MDD2_MOUSE/63-158              .................GQCQAGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQHVISQEMERIPR..L.RP.....PEPHPRDR......SGLVPR.KPGPAG........-------ELLTQG.....-----------nptgsspaaqg....................................
F6US37_HORSE/37-139              .................GQGQVGVGQLWPLQGFATPVFQNLQVVLQQIV...PQG...LFWKDGMTQDAMTQKMEHISR..P.HP.....QDPCLRDG......QAAFPT.RSTGVR........GKQEEKLRLLFPK.....SPVAKVTRDQC...............................................
PTPR2_HUMAN/59-142               .....grcqkvpamdfy------------RYEVSPVALQRLRVALQKLS...GTG...FTWQDDYTQYVMDQELADLPK..T.YL.....RRPE----......------.------........-------------.....-----------assparpskhsvgserrysre..........................
M7AWL5_CHEMY/559-675             .................GQCQESAARDSPYFQVTSPVLQRLQDVLHRLT...ARG...LSWRDDLTQYVIAQEMERIPR..L.RPp..paREPGAKER......------.------........-------------.....-----------fsplraaprmalfpsepsqpgsalqmaprqlpasaekaphlepqppl
W5KPX0_ASTMX/22-101              .................GRCQAMTAADVYTYDITPATLQRFRSLLQKLS...LRG...LSWEDDVTQQVLSKEFSKLRK..I.--.....--------......------.------........-------------.....-----------srtpldtrpmvqtvgagdarlkp........................
H0XDK2_OTOGA/37-140              .................GQDQVGVGQFWSLQGLTTPVFQNLQVILQQIV...PQG...LFWKNDITQDIFPQ-MEH---..F.NP.....QNPCLRDE......KAAFPT.KLTRGK........GKQKEKIRLLFPKlpssqSPVAKVNKDQC...............................................
F6R0M5_CALJA/60-157              .................GQCQVGVGQARPLLQVTSPVLQRLQSVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RL.....PEPRPRDR......SGLAPR.RPGPTG........-------ELL---.....-----------lqdiptgsapaaqlls...............................
F7E5U0_CALJA/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQSVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RL.....PEPRPRDR......SGLAPR.RPGPTG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
H9FXU7_MACMU/59-140              .....grcqkvpamdfy------------RYEVSPVALQRLRVALQKLS...GTG...FTWQDDYTQYVMDQELADLPK..T.YL.....RHPE----......------.------........-------------.....-----------asgparpskhsigserrys............................
K7EUG8_PONAB/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPR.RPGPAG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
G3WJ01_SARHA/22-113              .................GQCQTGAGRVRPLLQVTSPILQRLQSVLRQLM...SQGnhvIIWVDCLLILLLASPIFILPK..H.QD.....QEPK----......------.------........-------------.....-----------ncvtgktlenmncevradhtggrker.....................
U3D4X3_CALJA/60-153              .....grcqkvpamdfy------------RYEVSPVALHRLRVALQKLS...STG...FTWQDDYTQYVMAQELANLPK..T.YL.....RRPAVSSA......AGPSKQ.SIGS--........-------------.....-----------errysregsaalakalq..............................
M4A8F6_XIPMA/48-129              .................GQCRAP-DQKPVRYRVSGPVLLRLQEVLKDLM...VQG...LTWKDELTQSIISRELSWVPT..D.PV.....LDPDPEEN......------.------........-------------.....-----------ppkpssrllgpapqte...............................
Q9Y4I9_HUMAN/59-142              .....grcqkvpamdfy------------RYEVSPVALQRLRVALQKLS...GTG...FTWQDDYTQYVMDQELADLPK..T.YL.....RRPE----......------.------........-------------.....-----------assparpskhsvgserrysre..........................
I3K2I4_ORENI/47-137              .................GQCQAPHQEPV-QYQVSVPVLHKLQEVLKDLM...VQG...LNWKDDMTQAIISRELSQVPT..I.ET.....HSKLNEK-......------.------........-------------.....-----------spklssrllgsspqrgqgpedqadpk.....................
H0Z6G4_TAEGU/22-110              .................GQCQVGSVQDRPYFQVTSPVLQRLQDVLRHLM...AQG...LSWQDGITQYVISQEMERIPR..L.RLp..psLEPVARDR......------.------........-------------.....-----------dlplypgelpqrslpsrfl............................
W5MXC4_LEPOC/28-113              .................GQCQDSSVRERVTYEVSVPVLHRLQEVLKHLT...MQG...LSWQDDITQYIISQEMIHVPR..T.YS.....--------......------.------........-------------.....-----------stspkeafldqvpksaqssgklsysss....................
H0V3J5_CAVPO/60-152              .................GQCQVGVGQARPLLQVTSPVLQRLQAVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PELRPRDR......SGLMLR.RPVP--........-------------.....-----------tgelflqgiptgsaqa...............................
U3DU84_CALJA/59-152              .....grcqkvpamdfy------------RYEVSPVALHRLRVALQKLS...STG...FTWQDDYTQYVMAQELANLPK..T.YL.....RRPAVSSA......AGPSKQ.SIGS--........-------------.....-----------errysregsaalakalq..............................
E6ZJ13_DICLA/4-95                .................GRCQELAGANLYTYDISSLALQRLRILLQKLA...HRG...LTWQDDITQQVISRELSKLRN..V.PL.....--------......------.------........-------------.....-----------rhqaappslsssrdrklrpaqaelnrnlqqylt..............
F7H047_MACMU/60-145              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...KVWRD----------------..-.--.....--------......------.------........-------------.....-----------wnlvsyglsmpfprlqhihfaflyrsglaprrpgpagelllqdipt.
G3I619_CRIGR/12-114              .................GQGHVTSEPLWPFQGFAASIFRYLKYVLHQIV...PED...LFWTDELAQEVLTKKVEHLSR..L.HL.....HNPCRKEG......KAVSTT.ATTGVR........GKQEEKHGFLYPK.....NPAVKVSKDRC...............................................
X1WH84_DANRE/47-137              ................g-QCLAER-QERFRYRVTAVLLDRLQSLLQTLM...KEG...LTWQDDVTQSVIKKELSKVPK..I.PL.....SSG-TKNG......P-----.------........-------------.....-----------siesqsgstnqlnskqahpymdymi......................
RES18_HUMAN/37-138               .................GQDQVGVGQLWPLQGFATPVFQHLQVVLQQII...PQG...LFWKDDITQDAMIQKMEHASR..L.HP.....QEPCLKDG......KALFPT.KTTE--........--QEEKLQLLFPSe..thSPLAKVNRDQC...............................................
U3CT49_CALJA/59-152              .....grcqkvpamdfy------------RYEVSPVALHRLRVALQKLS...STG...FTWQDDYTQYVMAQELANLPK..T.YL.....RRPAVSSA......AGPSKQ.SIGS--........-------------.....-----------errysregsaalakalq..............................
V8P9P5_OPHHA/68-141              .................GQCQESSLRDQPYFQVTTPVLQRLQDILRHLM...AQG...LSWQDDLTQYVIAQEMEHIPR..L.HL.....PSS-----......------.------........-------------.....-----------wnsaaedrlppl...................................
U3DMN1_CALJA/60-153              .....grcqkvpamdfy------------RYEVSPVALHRLRVALQKLS...STG...FTWQDDYTQYVMAQELANLPK..T.YL.....RRPAVSSA......AGPSKQ.SIGS--........-------------.....-----------errysregsaalakalq..............................
Q5DTQ3_MOUSE/76-171              .................GQCQAGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQHVISQEMERIPR..L.RP.....PEPHPRDR......SGLVPR.KPGPAG........-------ELLTQG.....-----------nptgsspaaqg....................................
F6TGE3_CALJA/72-173              .................GQDQSRNGQLWPSKDCH-PSLPAFTSVLQQII...PRG...LFWKDDITQDVMTQKMEHVSR..L.HP.....QDPCLKDG......KAVFPT.KTTGSL........LAKLNR-------.....-----------drcftskviskalkqevs.............................
R4GHU3_CHICK/76-162              .................GQCQVGSVQDKPHFQVTSPVLQRLQDVLRHLM...AQG...LSWQDGITQYVISQEMERIPR..L.RPp..psLEPSPRDS......WGAVPR.CHP---........-------------.....-----------sllvprsl.......................................
I3K2I5_ORENI/22-112              .................GQCQAPHQEPV-QYQVSVPVLHKLQEVLKDLM...VQG...LNWKDDMTQAIISRELSQVPT..I.ET.....HSKLNEK-......------.------........-------------.....-----------spklssrllgsspqrgqgpedqadpk.....................
I3MHI4_SPETR/61-156              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLVPR.RPGPAG........-------ELLSQG.....TP---------tgsspaaqg......................................
M3YYW0_MUSPF/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQSVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.HP.....PEPRPRDR......SGLVPR.RPGPAG........-------ELLLQGiptgsTPAAQH-----rlpqp..........................................
M4ANC3_XIPMA/47-137              .................GQCQS-SKQDQIQYQVTVPVLKRMQEVLKQLM...LQG...LSWQDDITQYILSKELKRVPH..T.TA....lSKPISSSP......SSHSS-.------........-------------.....-----------hskqhvshhpnsksgstss............................
L5LWZ9_MYODS/33-101              ...............sa------------------------------IS...AHG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPHPRDR......SGLVPR.RPGPAE........-------------.....-----------elllqgiptgpapaaphr.............................
D2HQQ9_AILME/2-88                .................GQGQVGAEQLWTLQGFATPVFQHMQVVLQQIV...PQG...LFWKDGITQDVMAQK--HISR..F.HP.....QDPCLRHG......QAAFPT.KTTGIS........-------------.....-----------pvakvnseqc.....................................
PTPR2_MACNE/57-139               .....grcqkvpamdfy------------RYEVSPVALQRLRVALQKLS...GTG...FTWQDDYTQYVMDQELADLPK..T.YL.....RHPE----......------.------........-------------.....-----------asgparpskhsigserrysq...........................
B0KWI8_CALJA/1-70                .................-------------------------------M...SQG...LSWHDDLTQYVISQEMERIPR..L.RL.....PEPRPRDR......SGLAPR.RPGPTG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
F7ES91_MACMU/37-141              .................GQDQVGVEQLWPLQGFATPVFQHLQVVFQQIL...PQG...LFWKDDITQDAMIQKMEHTSR..L.HP.....QDPCLKDG......KAVFPT.KTAGKQ........A-RGETLTPIPHSe..shSPLAKVNRDQC...............................................
Q5R982_PONAB/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPR.RPGPAG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
C9JR27_HUMAN/27-128              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPK.RPGPAG........-------ELLLQDiptgsAPAAQH-----rlpqpp.........................................
G3T308_LOXAF/60-164              .................GQCQVGVGQVRPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRLRDR......SGLVPR.RPGPTGellsqgipTGSAPAAQHLLPR.....SPA--------gg.............................................
C9JJL7_HUMAN/1-74                .................-------------------------------M...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPK.RPGPAG........-------ELLLQDiptgsAPAAQH-----rlpqppvgk......................................
J9P792_CANFA/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQSVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLVPR.RPGPAG........-------ELLLQGlptgsTPAAQH-----rlpqp..........................................
PTPR2_MOUSE/58-140               ......grcqkvpvmdt-----------YRYEVPPGALLHLKVTLQKLS...RTG...FTWQDDYTQRVIAQELANLPK..A.YL.....--------......------.------........-------------.....-----------whgeasgparslqqnadnekwfsl.......................
G3SFN6_GORGO/74-161              .................GQDQVGVGQLWPLQGFATPVFQHLQVVLQQII...PQG...LFWKDDITQDAMIQKMEHASR..L.HP.....QDPCLKDG......KALFPT.KTTE--........-------------.....SPLAKVNRDQC...............................................
M3ZJM2_XIPMA/50-162              .................GRCQELAGADLYTYDISSSALQRLRILLQKLA...HRG...LTWRDDITQQVISRELSKLRNipV.HQ.....QSPSPSQL......TAYSSS.RNRKLR........PTQAELSRNLQQ-.....-----------yltglgfmpdpdtkqqenqp...........................
K9INK6_DESRO/56-148              .........grcqkvpv--------TDTYRYEVSPGVLQHLTTTLQRLS...RTG...FTWQDDYTQHVLAQELSYLPR..T.HL.....WCPR----......------.------........-------------.....-----------tahparilkpsaqderrrhpegslalaeal.................
H2QJG8_PANTR/79-166              .................GQDQVGVGQLWTLQGFATPVFQHLQVVLQQII...PQG...LFWKDDITQDAMIQKMEHASR..L.HP.....QDPCLKDG......KALFPT.KTTE--........-------------.....SPLAKVNRDQC...............................................
RES18_MOUSE/37-140               .................GQGQVGSEQLWTFQGLIASVFQYLQLIFHQIV...PEG...MFWADDIAYELMTKKVEHLSR..L.HP.....QYPCRKDM......KAVSPT.ANAGVR........SKQEEKLQLLSPQ....kSPTVKVNRDRC...............................................
M3WER6_FELCA/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQSVLRQLM...SQG...KSQTGDLRQHKVNKNKNRSDN..D.RP.....PEPRPRDR......SGLVPR.RPGSAG........-------ELLLQGiptgsTPAAQH-----rlpqp..........................................
Q6GPA6_XENLA/49-169              .................GQCRPRAERDDPPYQMATGTLQQLQGVLQQLT...AKG...FSWKDDMTPRLMAHKMGRISQ..H.RPl..epLDGLDEDRfplshaSGRTMQ.RLSGASqps.tprwASSSDKLQYFRPRl...pSPLG-------dtslqkp........................................
K6ZLK2_PANTR/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPHPRDR......SGLAPK.RPGPAG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
C9JK57_HUMAN/1-74                .................-------------------------------M...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPK.RPGPAG........-------ELLLQDiptgsAPAAQH-----rlpqppvgk......................................
RES18_RAT/37-140                 .................GQGQVGSEQLWTFQGLVASVFQYLQLLFHHIV...PQG...MFWTDDIAYELMTKKVEHLSR..L.HP.....QYPCRKEG......KVVSPI.ATTGVR........GKQEEKLRLLSPQ....kSPAVKVNRDRC...............................................
B3DJG5_DANRE/47-121              .................GQCRSSRH-DQVQYQVSVPVLQRLQQVLKELM...LQG...FSWQDEITQQIIAKELSRIPH..T.RT.....QKSQ----......------.------........-------------.....-----------naqppppaakkvy..................................
G7N8Z9_MACMU/37-137              .................GQDQVGVGQLWPLQGFATPVFQHLQVVFQQIL...PQG...LFWKDDITQDAMIQKMEHTSR..L.HP.....QDPCLKDG......KAVFPT.KTAGSP........LAKVNRDQCFTSK.....-----------vvskvlkqe......................................
H2UFW4_TAKRU/27-98               .................GQCL-SSKQDKVQYQVSVQVLKRMQEVLKQLM...LQG...LSWQDDITQYILSKELKRVPH..T.--.....--------......------.------........-------------.....-----------srtskssssfpsshsp...............................
B2GU79_XENTR/49-169              .................GQCRPRADRDDAPFQVPPGALQQLQGVLRQLT...AKG...FPWKDDMTPRLLAHEMGRIPQ..H.RPl..etLDGLDEDRsplslgSGRTMQ.RLPGMSqms.aprwAGSADKLQYFRPRl...pSPL--------gdtspqkp.......................................
G1RDV0_NOMLE/50-150              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPR.RPGPAG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
L8Y330_TUPCH/60-132              .................GQCQVGVGQARPLLQVTSPVLQRLQSVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.QP.....PEPRPRDR......------.------........-------------.....-----------lprplg.........................................
F1PMD6_CANFA/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQSVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLVPR.RPGPAG........-------ELLLQGlptgsTPAAQH-----rlpqp..........................................
F6U2N5_CALJA/65-164              .................GQDQSRNGQLWPSK-IAIPVFQHLQ-VLQQII...PRG...LFWKDDITQDVMTQKMEHVSR..L.HP.....QDPCLKDG......KAVFPT.KTTGSL........LAKLN--------.....-----------rdrcftskviskalkqev.............................
U6DLE8_NEOVI/59-159              .................GQCQVGVGQARPLLQVTSPVLQRLQSVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.HP.....PEPRPRDR......SGLVPR.RPGPAG........-------ELLLQGiptgsTPAAQH-----rlpqp..........................................
G5AKJ6_HETGA/60-155              .................GQCQVGVGQARPLLQVTSPVLQRLQAVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PETRQRDR......SGLMPR.RPVPAG........-------------.....-----------elllqgiptgsapaaqg..............................
F7D9P9_HORSE/64-163              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....TEPHPRDR......SGLVPR.RPGPTG........-------ELLLQGiptgsAPVAQH-----rlpr...........................................
G3HTT8_CRIGR/3-85                .............tyry--------------EVSPGALLHLRVTLQKLS...RTG...FTWQDDYTQHVMAQELANLPK..A.YP.....WHGD----......-TSSPA.R-----........-------------.....-----------tlqqnadnekwfspeseaalaktl.......................
H0VV96_CAVPO/19-106              .................GQGQADSGQLWPLKGFAAPFFHHLQVLLHQLI...SHG...LFWKDDIVQHLMTQNMEHMSR..L.YA.....HDPYLKGR......KSVLPT.KISQ--........-------------.....SPVPKVNRD--qc.............................................
L8IWF8_9CETA/37-139              .................GQSQVGVGQLWPLPGFTTPVFKHLQVLLQQIT...PHD...LFWKDDMTQEVMTQKMGHTSK..L.HP.....EDPCVRSG......PAAFPT.RTPGVR........GKQEEKLRLLFPK.....SPMVKVNKDQC...............................................
I3J8R2_ORENI/47-147              .................GQCRS-SKQDQVQYQVSVPVLKRMQEVLKQLM...LEG...LSWQDDITQYILSKELKRVPH..T.TL....pSKPNTSSL......SQQV--.------........-------------.....-----------hhqssksasaspsgkyvdymiveppqsplr.................
H2R644_PANTR/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPHPRDR......SGLAPK.RPGPAG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
H3DG99_TETNG/22-108              .................GQCL-SSKQDKVQYQVSVPVLKRMQEVLKQLM...LQG...LSWQDDITQYILSKELKRVPH..TsRA.....SKPSSSSP......SSHSPQ.DLCKF-........-------------.....-----------grssskips......................................
Q925J7_MOUSE/1-53                .................--------------------------------...---...--------QHVISQEMERIPR..L.RP.....PEPHPRDR......SGLVPR.KPGPAG........-------ELLTQG.....NP---------tgsspaaqg......................................
PTPR2_RAT/58-145                 ...............gr--CQKVPALDTYRYEVSPGALLHLRIILQKLS...RTG...FTWQDDYTQRVIAQELSNLPK..A.YL.....--------......------.------........-------------.....-----------wheeassparslqqnadnekwfsleseva..................
H2UFW6_TAKRU/27-98               .................GQCL-SSKQDKVQYQVSVQVLKRMQEVLKQLM...LQG...LSWQDDITQYILSKELKRVPH..T.--.....--------......------.------........-------------.....-----------srtskssssfpsshsp...............................
G5C8S2_HETGA/42-128              .................GRCQKVPGLDISRYEVSPVALQHLRATLQALS...RTG...FMWQEDDTQRIMAQELAGLLR..A.HP.....QHMET---......------.------........-------------.....-----------ssparvsqqnvdterqyslendv........................
L5L2A3_PTEAL/60-156              .................GQCQVGVGQARPLLQVTSPILQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PELHPRDR......SGSVPR.RPGPAG........-------------.....-----------elllqgiptgsapaaqpr.............................
F6RCL7_MONDO/54-153              .................GQCQTGAGRVRPLLQVTSPILQRLQGVLRQLM...SQG...LSWQDDLTQYVISQEMERIPR..L.RP.....PDPGSKDR......SSLAAR.RPALPG........-------ELLPPDpptgsAPAAQ------hrlpr..........................................
RES18_BOVIN/37-139               .................GQSQVGVGQLWPLPGFTTPVFKHLQVLLQQIM...PHD...LFWKDDMTQEVMTQKMGRTSK..L.HP.....EDPCVRSG......PAAFPT.RTPGVR........GKQEEKLRLLFPK.....SPMVKVNKDQC...............................................
F1SR77_PIG/37-139                .................GQGQVGVGQLWPLQGFTTPIFQHLQVVLQQIV...PQG...LFWKDDMTQNVMTQKMGHISQ..L.HP.....QDPCVRVG......QAASPT.KTTGAR........GKQEEKLRLLFPK.....SPVVKVNRDQC...............................................
T1DHQ2_CROHD/64-144              .................GQCQESSLRDQPYFQVTASVLQRLQAILRHLM...AQG...LSWQDDFTQYVIAQEMEHIPR..L.YL.....PSS-----......------.------........-------------.....-----------wnsaaedrlpphhlvprrp............................
Q8BT93_MOUSE/37-142              .................GQGQVGSEQLWTFQGLIASVFQYLQLIFHQIV...PEG...MFWADDIAYELMTKG-GAPQQ..T.PP.....PVSMQEGY......EGSFPHgKRWGEE........QARGETSTLISPK.....-----------esnsqgeqgpmlyh.................................
K7E663_MONDO/4-84                .............myry--------------EVTPPILEHLRTILQKLS...HRG...FTWQDDFTQGTVAQELANIPK..I.YQ.....WHPESLAS......DGVNSI.RTSKP-........-------------.....-----------kvdnkrpstlend..................................
U3FVJ4_CALJA/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQSVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RL.....PEPRPRDR......SGLAPR.RPGPTG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
PTPRN_RAT/66-163                 .................GQCQAGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPHPRDR......SGSVPR.RAGPAG........-------ELLSQG.....-----------nptgsspavqgls..................................
I2CY08_MACMU/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPR.RPGPAG........-------ELLLQD.....-----------iptgsapasqhrlpqp...............................
G7PK47_MACFA/37-137              .................GQDQVGVGQLWPLQGFATPVFQHLQVVFQQIL...PQG...LFWKDDITQDAMIQKMEHTSR..L.HP.....QDPCLKDG......KAVFPT.KTAGSP........LAKVNRDQCFTSK.....-----------vvskvlkqe......................................
W5MXD0_LEPOC/48-133              .................GQCQDSSVRERVTYEVSVPVLHRLQEVLKHLT...MQG...LSWQDDITQYIISQEMIHVPR..T.YS.....--------......------.------........-------------.....-----------stspkeafldqvpksaqssgklsysss....................
G7PK46_MACFA/25-125              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPR.RPGPAG........-------ELLLQD.....-----------iptgsapasqhrlpqp...............................
C9JCQ0_HUMAN/1-75                .................-------------------------------M...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPK.RPGPAG........-------ELLLQDiptgsAPAAQH-----rlpqppvgkg.....................................
E1BYQ1_CHICK/62-157              ...............gr--CQRVPVRDIYKYDISPPVLQRLRIILEKLS...HRG...FTWQDDYTQHVIGQELSNIHR..V.HN.....RRPDIFVS......EAS---.------........-------------.....-----------dtgrileqnednerkshlendvnlae.....................
B9W0B0_MOUSE/37-120              .................GQGQVGSEQLWTFQGLIASVFQYLQLIFHQIV...PEG...MFWADDIAYELMTKKVEHLSR..L.HP.....QYPCRKDM......KAVSPT.ANAGVR........VQQ----------.....-----------sr.............................................
W5K3K7_ASTMX/22-91               .............gqcl-----GPQQDRFRYRVNASLLDRLQSLLQMLM...KEG...LTWRDDVTQSLIDKELSKVVK..-.--.....--------......------.------........-------------.....-----------ipvlsavknapspgs................................
G3R874_GORGO/73-173              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPK.RPGPAE........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
G1U816_RABIT/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGVVPR.QPGPAG........-------ELLSQG.....-----------iptgsapaaqlglprp...............................
G3INC6_CRIGR/1-65                .................-------------------------------M...SQG...LSWHDDLTQHVISQEMERIPR..L.RP.....PEPHPRDR......SSLVPR.RPGPAG........-------ELLSQG.....NP---------tgsspaaqg......................................
C0HAC4_SALSA/47-138              ...........gqcllp-------QQERVLYEVSVPVLHRLQEVLKELM...MQG...LSWQDDITQYVIRKELSRVSL..T.RP.....SSGRHDNP......SSQS--.------........-------------.....-----------sepvqnahlskmqyppssrtka.........................
F6PIZ6_CALJA/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQSVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RL.....PEPRPRDR......SGLAPR.RPGPTG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
F6TF72_CALJA/33-132              .................GQDQVGMGNFGPPR-IAIPVFQHLQ-VLQQII...PRG...LFWKDDITQDVMTQKMEHVSR..L.HP.....QDPCLKDG......KAVFPT.KTTG--........--QGERLQLLFPGe..thSLLAKLNRDRC...............................................
A3KN68_MOUSE/58-128              .......grcqkvpvmd----------TYRYEVPPGALLHLKVTLQKLS...RTG...FTWQDDYTQRVIAQELANLPK..A.--.....--------......------.------........-------------.....-----------ylwhgetsgpprsl.................................
Q925J6_MOUSE/1-53                .................--------------------------------...---...--------QHVISQEMERIPR..L.RP.....PEPHPRDR......SGLVPR.KPGPAG........-------ELLTQG.....NP---------tgsspaaqg......................................
G3QNU1_GORGO/79-166              .................GQDQVGVGQLWPLQGFATPVFQHLQVVLQQII...PQG...LFWKDDITQDAMIQKMEHASR..L.HP.....QDPCLKDG......KALFPT.KTTE--........-------------.....SPLAKVNRDQC...............................................
G7N8Z8_MACMU/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPR.RPGPAG........-------ELLLQD.....-----------iptgsapasqhrlpqp...............................
G1PAU4_MYOLU/66-162              .................GQCQVGVGQARPLFQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPHPRDR......SGLVPR.RPGPAE........-------------.....-----------elllqgiptgpapaaphr.............................
G1MEF3_AILME/37-140              .................GQGQVGAEQLWTLQGFATPVFQHMQVVLQQIV...PQG...LFWKDGITQDVMAQK--HISR..F.HP.....QDPCLRHG......QAAFPT.KTTGIR........GKQKEKLRLLFPKp..sqSPVAKVNSEQC...............................................
A8MW94_HUMAN/1-56                .................--------------------------------...---...-----------MIQKMEHASR..L.HP.....QEPCLKDG......KALFPT.KTTE--........--QEEKLQLLFPSe..thSPLAKVNRDQC...............................................
U3JNT8_FICAL/1-49                .................-------------------------------M...AQG...LSWQDGITQYVISQEMERIPR..L.RLp..psLEPVARDR......------.------........-------------.....-----------flplrsehrr.....................................
L8IW25_9CETA/69-169              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPHPRDR......SGLVPR.RPGPAG........-------------.....-----------elllqgiptgsapalqhrlprp.........................
G1T8W0_RABIT/37-139              .................GQGQVGAGQLWSLQGFTTPVFWHLQVVLQQIV...PQG...LFWKDDITQDVMTQKMEHISR..L.HP.....QDPCMKDG......KAVFPT.KTSGVR........GKKEDKLRLLFPK.....SPVAKMNKEQC...............................................
H0XDJ7_OTOGA/60-156              .................GQCQVGMGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.HP.....PESRSRDR......SGLAPR.RPGPAG........-------QLLLQG.....-----------iptgsvpaaqqr...................................
I3MHI7_SPETR/37-139              ................c-KSQVGAEQPWPVQGFTASVFRQLQVILHQIV...PQG...LFWKEDTTQDVMIQKMKHISL..L.HP.....QDACMKDG......KAVFPT.KTTAMR........GKQEEKLQLLFPK.....SPVSKLNRDQC...............................................
S9Y636_9CETA/457-529             ttgvlqtltlfkspvtk--------------------------------...---...---------------VNREQR..L.NSe..vvSEALSREA......TSPSKA.LLCVFR........GKQEEKLRLLFPK.....SPMAKVNKDQC...............................................
Q59FU1_HUMAN/32-132              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPK.RPGPAG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
G3NSZ9_GASAC/22-121              .................GQCRTSKQ-DLVQYQVTVPVLKRMQEVLKQLMlgaRTG...LSWQNDITQYILSKELKRVPH.tT.HP.....SRPNPSSS......SSHSSQ.SVPS--........-------------.....-----------syrdphhhlftagpglsslp...........................
Q571D4_MOUSE/82-164              ......grcqkvpvmdt-----------YRYEVPPGALLHLKVTLQKLS...RTG...FTWQDDYTQRVIAQELANLPK..A.YL.....--------......------.------........-------------.....-----------whgeasgparslqqnadnekwfsl.......................
Q3UU93_MOUSE/58-140              ......grcqkvpvmdt-----------YRYEVPPGALLHLKVTLQKLS...RTG...FTWQDDYTQRVIAQELANLPK..A.YL.....--------......------.------........-------------.....-----------whgeasgparslqqnadnekwfsl.......................
PTPRN_MOUSE/63-158               .................GQCQAGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQHVISQEMERIPR..L.RP.....PEPHPRDR......SGLVPR.KPGPAG........-------ELLTQG.....-----------nptgsspaaqg....................................
H9EW26_MACMU/60-160              .................GQCQVGVGQARPLLQVTSPVLQRLQGVLRQLM...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPR.RPGPAG........-------ELLLQD.....-----------iptgsapasqhrlpqp...............................
C9J392_HUMAN/1-66                .................-------------------------------M...SQG...LSWHDDLTQYVISQEMERIPR..L.RP.....PEPRPRDR......SGLAPK.RPGPAG........-------ELLLQDiptgsAPAAQ------hr.............................................
F7GFM0_CALJA/67-166              .................GQDQVGMGNFGPPR-IAIPVFQHLQ-VLQQII...PRG...LFWKDDITQDVMTQKMEHVSR..L.HP.....QDPCLKDG......KAVFPT.KTTESL........-------------.....-----------laklnrdrcftskviskalkqev........................
F7GWZ3_CALJA/1-70                .................-------------------------------M...SQG...LSWHDDLTQYVISQEMERIPR..L.RL.....PEPRPRDR......SGLAPR.RPGPTG........-------ELLLQDiptgsAPAAQH-----rlpqp..........................................
#=GC seq_cons                    .................GQsQsustQ.hshhpVosPVLQRLQsVLppLh...sQG...LoW+DDlTQaVloQEMc+lPR..L.+s......-Pp.+ct......puh.Pp.+.s........................................th..s..........................................
//
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