GenomeNet

Database: Pfam
Entry: RE_Eco47II
LinkDB: RE_Eco47II
Original site: RE_Eco47II 
#=GF ID   RE_Eco47II
#=GF AC   PF09553.5
#=GF DE   Eco47II restriction endonuclease
#=GF AU   Coggill P
#=GF SE   Bateman A
#=GF GA   25.00 25.00;
#=GF TC   27.00 27.00;
#=GF NC   20.90 19.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   7607524
#=GF RT   Cloning and characterization of the unusual
#=GF RT   restriction-modification system comprising two restriction
#=GF RT   endonucleases and one methyltransferase. 
#=GF RA   Stankevicius K, Povilionis P, Lubys A, Menkevicius S, Janulaitis
#=GF RA   A; 
#=GF RL   Gene. 1995;157:49-53.
#=GF RN   [2]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR019057;
#=GF CC   This family includes the Eco47II (which recognises GGNCC, but
#=GF CC   the cleavage site unknown) restriction endonuclease.
#=GF SQ   64
#=GS F7R394_9LACO/1-68     AC F7R394.1
#=GS H7PBB7_STRPN/4-218    AC H7PBB7.1
#=GS C0B3B5_9ENTR/1-150    AC C0B3B5.1
#=GS D9QWM8_MYCMG/7-215    AC D9QWM8.1
#=GS G2Z687_FLABF/6-209    AC G2Z687.1
#=GS B6FL64_9CLOT/5-219    AC B6FL64.1
#=GS F0VUH1_STRG2/4-222    AC F0VUH1.1
#=GS H7JWL5_STRPN/4-218    AC H7JWL5.1
#=GS F5ZK20_STRPW/2-131    AC F5ZK20.1
#=GS D4LCI8_RUMC1/4-222    AC D4LCI8.1
#=GS Q6MU28_MYCMS/7-215    AC Q6MU28.1
#=GS G6VPG7_STRPN/4-218    AC G6VPG7.1
#=GS B7AWL7_9FIRM/5-223    AC B7AWL7.1
#=GS D3VQL5_MYCA6/5-199    AC D3VQL5.1
#=GS D4BU19_PRORE/4-215    AC D4BU19.1
#=GS A9E2M7_9FLAO/6-208    AC A9E2M7.1
#=GS G9XEH6_9FIRM/4-222    AC G9XEH6.1
#=GS E4KME8_9LACT/5-223    AC E4KME8.1
#=GS H7EJD8_9SPIO/1-147    AC H7EJD8.1
#=GS C2L0T9_9FIRM/5-136    AC C2L0T9.1
#=GS C3WLL6_9FUSO/4-222    AC C3WLL6.1
#=GS F9S6I5_9VIBR/1-37     AC F9S6I5.1
#=GS F6FFU2_MYCHI/12-221   AC F6FFU2.1
#=GS A7VX93_9CLOT/5-223    AC A7VX93.1
#=GS T2E8_ECOLX/4-215      AC P50195.1
#=GS F8K769_MYCL9/7-203    AC F8K769.1
#=GS B8CH65_SHEPW/7-206    AC B8CH65.1
#=GS F3SHI9_STRSA/5-219    AC F3SHI9.1
#=GS F9S6J1_9VIBR/16-190   AC F9S6J1.1
#=GS C0B3B4_9ENTR/4-72     AC C0B3B4.1
#=GS E1KSX9_9BACT/6-210    AC E1KSX9.1
#=GS Q5ZW50_LEGPH/18-230   AC Q5ZW50.1
#=GS E8ZJ77_MYCHL/12-51    AC E8ZJ77.1
#=GS D0K1E2_HELP5/7-212    AC D0K1E2.1
#=GS D4JJV6_9FIRM/5-223    AC D4JJV6.1
#=GS F3TL34_STAAU/6-218    AC F3TL34.1
#=GS G5EPA7_9MICC/6-222    AC G5EPA7.1
#=GS I0T9W0_9BACT/8-208    AC I0T9W0.1
#=GS E4PTM4_MYCLG/7-203    AC E4PTM4.1
#=GS D6YSJ0_WADCW/5-205    AC D6YSJ0.1
#=GS F3BBJ9_9FIRM/5-219    AC F3BBJ9.1
#=GS E4TRM8_MARTH/6-209    AC E4TRM8.1
#=GS G6V5P1_STRPN/4-218    AC G6V5P1.1
#=GS H8BW37_CAMJU/7-212    AC H8BW37.1
#=GS F4MP99_MYCML/7-215    AC F4MP99.1
#=GS H7K9F6_STRPN/4-218    AC H7K9F6.1
#=GS F7JFS2_9FIRM/3-110    AC F7JFS2.1
#=GS G5EPA8_9MICC/6-224    AC G5EPA8.1
#=GS G1WDB9_9BACT/6-215    AC G1WDB9.1
#=GS F5W392_STAAU/6-218    AC F5W392.1
#=GS F3AQK1_9FIRM/5-219    AC F3AQK1.1
#=GS F2Y147_9PHYC/4-168    AC F2Y147.1
#=GS T2S9_STAAU/6-218      AC P23736.1
#=GS E5XE96_9FIRM/5-219    AC E5XE96.1
#=GS F0RE65_CELLC/6-209    AC F0RE65.1
#=GS Q3D667_STRAG/4-222    AC Q3D667.1
#=GS D0GVW4_VIBMI/2-210    AC D0GVW4.1
#=GS F7JFS3_9FIRM/5-115    AC F7JFS3.1
#=GS D4M4D1_9FIRM/5-219    AC D4M4D1.1
#=GS G5KZ23_STRSU/4-222    AC G5KZ23.1
#=GS C2L0T8_9FIRM/1-87     AC C2L0T8.1
#=GS E6UEZ3_RUMA7/4-222    AC E6UEZ3.1
#=GS I0SCJ8_STRAP/5-223    AC I0SCJ8.1
#=GS D1J7H6_MYCHP/343-548  AC D1J7H6.1
F7R394_9LACO/1-68                ........................................mh-----------------.--.----.-------------------------------------------------------------.--.------....---..-----.--............-----------------------------------------VFLVEAIAKKSQNIKWETSVDNQKV-----...GHMLIHRVSMDKFYALVTGQDDAFYQICMPLPEVIQKVVE-t..................
H7PBB7_STRPN/4-218               ..........................................LSFISEKD----VQLTI.DK.YREK.LQSFDLKRFNKNIVDPIKLIFDKSVYRSSWEQIISNEIFRQRDKSNNNDIGYFHQTIFKYI.EH.CRVPNNgedgGWD..VIFEN.TNgiimp..dgsrvSRVYVEMKNKHNTMNSASSGKTFIKIQNQLLQD----DDCECFLVKAIAKNSQNIKWEPKVDGQKM-----...GHKYIRRVSLDQFYSLVTGQKDALYNMCMVLPEVINKAVSE...................
C0B3B5_9ENTR/1-150               ........................................mp-----------------.--.----.-------------------------------------------KTIQNHVGTFHQRVLGYV.DG.WEDMGT....GGI..VDLVN.RE............KKIIAESKNKFNTVTGGSLSGVYHSLDAQVSPKHSQFKGFTAYFVNIIPKKPIRYNDPFTPSNKDTGAKCP...ENPLIRIIDGASFYHIVTERVDALKELHKALPKVIEHVYQ-e..................
D9QWM8_MYCMG/7-215               ..........................................LDFISKQDFEKHVTDTI.NQ.YKES.LKSISLKKLNRNIVDPIKLIFDKNIFNKEFKEIIELEISRQRDKTNNNVIGYFHQNIFKYI.KN.CKVPPQ....GWD..VIFQS.SE............YTYYVEMKNKHNTMNSVTASGIYMKMQNHLLNYDNN-EKSVCALVEVIAKRSQNIPWVMKIKNQKPI----...GNRRIKRISIDKFYEIVTGIKDSFKNLCLQLPITLEKLVSE...................
G2Z687_FLABF/6-209               ..........................................VDFVSDDHFLKCVANLH.IA.YLKA.KNNVTKKHFYSNKVDTIKLTFDAKFNAIDEESLIRAEILRQIDKSINNSIGTFHEQILGGI.AG.FEVGNL...sGF-..-DIKA.TD............NSLFADIKNKHNTMNSSSAEALFQK----LSRYADDYKKSKCYWVQVLAKTSFCELWKGDINGKEY-----...GHSRVYKISGDQFYALLSGQKDALFQLYKSLPIAINDYLE-s..................
B6FL64_9CLOT/5-219               ..........................................LDFLSEEDFRNHVRATI.MK.YGEK.LESYDLKKFNSNLIDPIKLIFDKSVYRTSWEEIVNNEIFRQRDKSNNNDIGYFHQNIFAYF.KG.CEVPQE....GWD..VIYKN.PDgiqmp..dgdivHTVYVEMKNKHNTMNSASSAKTYIKMQGQILED----DDCACLLVEAIAKKSQNIKWTTKVDGKNV-----...QHRLIRRVSMDQFYSILTGDENAFYKMCMALPEVINSVVNE...................
F0VUH1_STRG2/4-222               .........................................l-LFISEDDFYNHVQLTI.DK.YGEK.LQSFDLKRFNKNIVDPIKLIFDKSVYRSSWEQIISNEIFRQRDKSNNNDIGYFHQTIFKYI.EN.CRVPNNgeegGWD..VIFEN.PNgitmp..dgsrvSRVYVEMKNKHNTMNSASSGKTFIKMQNQLLQD----DDCACFLVEAIAKNSQNIKWEPKVDGQKM-----...GHKYIRRVSLDKFYALVTGEEDAFYKMCMVLPEVISKAVSE...................
H7JWL5_STRPN/4-218               ..........................................LSFISEKD----VQLTI.DK.YREK.LQSFDLKRFNKNIVDPIKLIFDKSVYRSSWEQIISNEIFRQRDKSNNNDIGYFHQTIFKYI.EH.CRVPNNgedgGWD..VIFEN.TNgiimp..dgsrvSRVYVEMKNKHNTMNSASSGKTFIKIQNQLLQD----DDCECFLVKAIAKNSQNIKWEPKVDGQKM-----...GHKYIRRVSLDQFYSLVTGQKDALYNMCMVLPEVINKAVSE...................
F5ZK20_STRPW/2-131               ....................................plkgkd-----------------.--.----.-------------------------------------------------------------.--.-----G....GWD..VILED.DHnille..dgskeSRVYVEMKNKHNTMNSASSGKTFIKMQNQLLND----DDCACFLVEAIAKKSQNIKWQPKVYGKNM-----...GHKYIRRVSLDKFYYLVTGEEDAFYKLCMVLPDILKKALN-k..................
D4LCI8_RUMC1/4-222               ..........................................LSFISEEDFTKHVKKTI.EK.YGEK.LESFDLKRFNKNIIDPIKLIFDKTVYQASWEEIVSNEIFRQRDKSNNNDIGYFHQRIFNYI.DK.CHVPDNgkegGWD..VIFEN.PDgialp..dgsvvHTIYVEMKNKHNTMNSASAGKTFIKMQNQLLTD----DDCACFLVEAIAQRSQNIKWETTVDKKKV-----...GHKLIRRVSLDQFYALVTGQEDAFYQLCMVLPSIIQKAVDE...................
Q6MU28_MYCMS/7-215               ..........................................LDFISKQDFEKHVTDTI.NQ.YKES.LKSISLKKLNRNIVDPIKLIFDKNIFNKEFKEIIELEISRQRDKTNNNVIGYFHQNIFKYI.KN.CKVPPQ....GWD..VIFQS.SE............YTYYVEMKNKHNTMNSVTASGIYMKMQNHLLNYDNN-EKSVCALVEVIAKRSQNIPWVMKIKNQKPI----...GNRRIKRISIDKFYEIVTGIKDSFKNLCLQLPITLEKLVSE...................
G6VPG7_STRPN/4-218               ..........................................LSFISEKD----VQLTI.DK.YREK.LQSFDLKRFNKNIVDPIKLIFDKSVYRSSWEQIISNEIFRQRDKSNNNDIGYFHQTIFKYI.EH.CRVPNNgedgGWD..VIFEN.TNgiimp..dgsrvSRVYVEMKNKHNTMNSASSGKTFIKIQNQLLQD----DDCECFLVKAIAKNSQNIKWEPKVDGQKM-----...GHKYIRRVSLDQFYSLVTGQKDALYNMCMVLPEVINKAVSE...................
B7AWL7_9FIRM/5-223               ..........................................LKFISQENFVKHVEATI.DK.YGEK.LESFDIKRFNKNIIDPIKLIFDKTVYQSTWEEMVGNEIFRQRDKSNNNDIGYFHQTIFQYM.KN.CHVPENgkegGWD..VIYEN.ADgiqlp..egdvvHKIYVEMKNKHNTMNSASTGKTYMKMQNQLLND----DDCACFLVEAIAQKSQNITWNPTVDGKKI-----...SHKRIRRVSIDQFYALVTGEEDAFYQMCMVLPEVIESVV--vk.................
D3VQL5_MYCA6/5-199               ................................fryskkalft-----------------.--.----.LRIYNLKRFNKNLIDPIKLVFDKNVFNKTFEEIIELEILRQRDKTNNNLIGYFHQNIFKYI.KN.CTVPKH....GWD..IIFKN.NI............TTYYVELKNKHNTLNSSSSSNTFIKMQDKLLSEGNK-DNVICALVEVIAAYSQDIPWIRNINNKRI-----...VNQKIRRISIDKFYEIVTGEKDAFKNLCLQLPITIEKIVN-n..................
D4BU19_PRORE/4-215               ..........................................LEYIPDDNLIKEVKYLL.DK.AVEK.RQDAE-KSFNKNVIDPFGALFEASDFK-SHEEWRNSEMARQCQKTIQNHVGTFHQRVLGYV.DG.WEDLGT....GGI..VDLIN.RE............KKIIAESKNKFNTVTGGSLSGVYHSLDAQVSPKHSQFKDFTAYFVNIIPKKPIRYNEPFTPSNKDTGARCP...VNPLIRIIDGASFYHIVTGRKDALKELHEALPKVIETV---yqq................
A9E2M7_9FLAO/6-208               ..........................................VDFVSDEHLISCISELY.TK.YLKA.KASYTKTDFNKNKVDVFKMLFDKKFNNLNDEDLIEKEISRQVDRTIVNAIGDFHENILNGV.HG.YSKVPA....GI-..-DIKS.ED............NKVFIELKNKHNTVKGEDNKSIFTKLKGEINKN----PGSKAYFARILDKKSTNKQWCFSHKKTEY-----...TDKNVLIISGDQLYKIITGKDNSLFELYQNLPQAIDDFLA-t..................
G9XEH6_9FIRM/4-222               ..........................................LTFITEEDFTNHVKSTI.EK.YGEK.LESFDLKRFNKNIIDPIKLIFDKTVYQSSWEEIVSNEIFRQRDKSNNNDIGYFHQRIFQYV.AN.CHVPPNgeegGWD..VIYEN.DNgieip..dagsvHTVYVEMKNKHNTMNSASAGKTFIKMQNQLLND----DDCACFLVEAIAQRSQNIKWETTVDKKKV-----...GHKLIRRVSLDQFYALVTGQEDAFYQMCMVLPTVIEKAVKD...................
E4KME8_9LACT/5-223               ..........................................IDFISQEDFKKHVKNTI.KH.YGTK.LVSYDVKKFNRNFIDPVKMIFDKAVYGEDWETIIANEIFRQRDKSNTNEIGYFHQRIFNYI.EH.CRVPDNgkegGWD..VIYES.PEgyvld..ngnevAKVCVELKNKHNTMNSSSAGKTYMKMQNQLLHD----DNCVCFLVEAIAARSQNIIWQTTVDGQKV-----...SHNRIRRVSIDRFYEIVTGQSDAFYQICKVLPEIVKEVIDE...................
H7EJD8_9SPIO/1-147               .....................................mekyr-----------------.--.----.-YHIDLAEFNKNPIDPIKLTFDSKVCNQIIQQTIEAECIRRIGKTNTNHIGCFHQNMFKLAgNG.WEVPKN....GADgaFYVAS.HK............KHIFCELKNKRNTMNSASSQKTYIEMQSKILED----DKAVCYEAEAIAAKYKDIPR--------------...-----------------------------------------aknkweek...........
C2L0T9_9FIRM/5-136               ..........................................LQFISQENLIKHVKATI.DK.YGEK.LESFDIVRFNKNIIDPVKMIFDKTVYQSSWEEIIGNEIFRQRDKSNNNDIGYFHQRIFQYI.SG.CHVPDNgtegGWD..VVFKK.ESgidlp..egdkvGTIYVEMKNKHNTMNS-------------------------------------------------------...-----------------------------------------...................
C3WLL6_9FUSO/4-222               ..........................................LKFISKENFYKHIQDTI.EK.YGEK.LESYDLKKFNKNIIDPIKLIFDKTVYSSSWNEIINSEIFRQRDKSNNNDIGYFHQRIFQYI.DN.CKVPENgedgGWD..VIYED.KDgitlp..egttvHKIYVEMKNKHNTMNSSSASKTFIKMQNQLLND----DDCACFLVEAIAQHSQNIKWETTVDKQKV-----...SHKLIRRVSMDQFWSLVTGEEDAFYKICMLLPEVIKEVIQD...................
F9S6I5_9VIBR/1-37                ..........................................-----------------.--.----.-------------------------------------------------------------.--.------....---..-----.--............-----------------------------------------------------------------------...----MRVIDGASFYDLATGRRDALKELHEVLPRVIEKVYQ-e..................
F6FFU2_MYCHI/12-221              ..........................................LSFISQKDFENHIKDTI.AG.YSEA.LKSINLKRFNSNLIDPIKLIFDKNVFGTTYEELIQLELHRQRDKTNSNIIGHFHQNIFKFI.SN.CTVPKQ....GWD..VIVKS.PK...........gNTFYVEIKNKHNTMNSSSASKTYMKFQSHLLTAADK-NESICMLVEVIAKESRDIPRVVSIDGVRQ----P...EHSRIRRVSVDKFYEYVTGDRLAFWKLCEQLPRTIEMLI--gk.................
A7VX93_9CLOT/5-223               ..........................................LTFISEEDFSNHVKATI.EK.YGEK.LESFDLKRFNKNIIDPIKLIFDKTVYQSSWEEIVSNEIFRQRDKSNNNDIGYFHQRIFQYI.KN.CHVPPNgeegGWD..VIYEN.ADgipip..dagnvHTVYVEMKNKHNTMNSASAGKTFIKMQNQLLND----DDCACFLVEAIAQRSQNIKWETTVDKKKV-----...GHKLIRRVSLDQFYALVTGQNDAFYQMCMVLPSVIEKAVKE...................
T2E8_ECOLX/4-215                 ..........................................LEYISDEDLFNEVETLL.TK.AKKK.KDAAE-KTFTSNVIDPFGALFEAPGFS-SHEEWRNSELARQQQKTIQNHVGTFHQKILGHV.EG.WRDMGI....GGI..VDLLN.EE............RRIIAEVKNKYSTVTGGDLADKYKGLDELVSPKHSRFKDYCAYFVNIIPRKPTRYNSPFTPSNKGSGTLCP...SNPNIRIIDGASFYELVTGRPDALQELHSALPHAIEYILSE...................
F8K769_MYCL9/7-203               ..........................................LDFIKQEDFEKHAIDTI.NQ.YRET.LKSINLKKFNRNIIDPIKLIFDKNIFNKEFKEIIELEISRQRDKTNNNVIGYFHQNIFKYI.KN.CKVPSQ....GWD..IIFQG.DE............NTYYVEMKNKHNTMNSVAASGIYMKMQNHLLNYDND-EKSICALVEVIAKHSQNIPWVMKIENQKLI----...GNRRIKRMSIDKFYEIVTGNKNSFKNLC-------------l..................
B8CH65_SHEPW/7-206               ..........................................LEFISDEDLFAHVKKTV.DK.YRF-.--SINLKEFNKNLIDPIKLTFDSKVYRKSIEEVIEAEALRQIDKSNTNHIGYFHQNIFEYF.EG.WEVPSK....GFD..VI--N.TE............KKVFVEMKNKHNTMNSASSQKTYIKMQSKILRD----DESTCYLVEVIAKDSQDFPWKISLDGESV-----...SNKNIRRMSIDKFYQLVTNNKDAFKLICQKLPLVIDDVISE...................
F3SHI9_STRSA/5-219               ..........................................LNFISEKDFYNHVKATI.EK.YGEK.LQSFDLKRFNKNIIDPIKLIFDKTVYHNSWDEIIKSEIFRQRDKSNNNDIGYFHQKIFRYI.EH.CKVPKE....GWD..VIYKN.PKgitlp..dgsivSSIYVEMKNKHNTMNAASSGKTFIKMQNQILKD----DDCACFLVEAIAKKSQNIKWEPKVDGKKM-----...GHKFIRRVSLDQFYALVTGQDDAFYQMCMILPKVIKNVVSE...................
F9S6J1_9VIBR/16-190              ..........................................LKFISDDDLFHEVRLLV.KK.TIIK.RNKAE-KDFNKNVVDPFCSLFEAPAFA-NHEAWRSAELMRQTQKTIQNHVGTFHQQILGHV.VG.WEDLGV....GAV..VDLKN.ID............RKIIAEVKNKYSTVTGGDLSNKYKSLENLVKPKHSGFKGFTAYFVQIIPRKPERYNEPFTPSDKETGDLCP...AN---------------------------------------dl.................
C0B3B4_9ENTR/4-72                ..........................................LEYISDENLIREVKYLL.DK.AVQK.RQDAE-KSFNKNVIDPFGALFEASDFK-SHEEWRNSEMARQCQKL----------------.--.------....---..-----.--............-----------------------------------------------------------------------...-----------------------------------------fkt................
E1KSX9_9BACT/6-210               ..........................................LGFISDKDIYNHVRATV.KQ.YRR-.--SINMKEFNKNIIDPIKLTFDAKIYNQSLEETIKSECIRQIDKTNNNRIGYFHQYLSKYAgNG.WEVPAN....GVKggFDVIN.DE............LHIYAEMKNKHNTMNSASASKTYMKMQNKLLRD----DKATCVLVEVISRKSQDITWKVTVDKEQF-----...NNNRIRKMSIDKFYEMVFHDSKAFFKLCMALPKILDDILE-a..................
Q5ZW50_LEGPH/18-230              ..........................................VSFIDDNTFENIVSDTI.NV.ASNA.MSNSK-KKFEKNVIDPFLTIFEISGFRIDSTEWLEHEKWRQAQKSLSNSIGIFHQKLLGSI.NG.WECLPT....GHI..VDIVN.HE............KRIIAEIKNKYNTIKGSAKAKLYHDLDDLVMQKKQEYKEYTAYYVEIIPKKPERYNQPFTPSDSRKGAKCA...ANEKIRVIDGYSFYSLASGIQNALEAIYQALPLVIQKILP-d..................
E8ZJ77_MYCHL/12-51               ..........................................LSFISQKDFENHIKDTV.AG.YSEA.LKPINLRRFNG--------------------------------------------------.--.------....---..-----.--............-----------------------------------------------------------------------...-----------------------------------------lfiinf.............
D0K1E2_HELP5/7-212               ..........................................LTFIKQKDFEEHVFNTI.KE.YKDT.LKSIDLAKFNANVIDPIKLCFDKNIFNLPYEKIIQKEIERQRDKSNNNSIGYFHQNIFKYI.KN.CEVPKN....GWD..VIVHK.ND............VNYYIEMKNKHNTMNSAASSKTYMRMQNTLLSE----PNCICVLVEVIAKFSSDKEWVITLDGEKQ----S...FNPRLRRISIDKFYHLVTDDNLAFKKLCLQLPITLKALL--hs.................
D4JJV6_9FIRM/5-223               ..........................................LKFISQENFVKHVEATI.DK.YGEK.LESFDIKRFNKNIIDPIKLIFDKTVYQSTWEEMVGNEIFRQRDKSNNNDIGYFHQTIFQYM.KN.CHVPENgkegGWD..VIYEN.ADgiqlp..egdvvHKIYVEMKNKHNTMNSASTGKTYMKMQNQLLND----DDCACFLVEAIAQKSQNITWNPTVDGKKI-----...SHKRIRRVSIDQFYALVTGEEDAFYQMCMVLPEVIESVV--vk.................
F3TL34_STAAU/6-218               ..........................................LSFITDEDLFECIEFLY.TE.YEKA.LEGIDFDKFFKNRIDTFKMTFDMGINNLSEQDWLAAELQRQVEKTITNHVGTFHEKLIGKI.EG.YTNYPV....GYD..YDVAK.DD............NTLFAEIKNKHNTLTGTHTKSLFQK----ICGYAEKYPDAICYYVRIIDTKSRNDIWEFRSGSIDENTREKprfSHPRVRIASGDQFYKIVTGEEDAFKQLAYNIPIALDDWIE-t..................
G5EPA7_9MICC/6-222               ..........................................LSWIDNEKLYNVTKDTLvSS.FKKQ.KEEFD-PYNNKNVIDPVSAVFHMFVLGLDFEEWESYERLRQVGKTLQNAIGNWHQKVLGLA.KN.WEDKGT....KGV..YDLES.KTkltgfepkpenpKIVIAEVKNKFNTIKGDTQHNYHEKLREQIGSR---GKDATAYLIQIVPKNKERYNKPWVPPNSKE-----...-NIYIRHIDGHSAYDLLFSHPGALKELYDALPNILSDIVSE...................
I0T9W0_9BACT/8-208               ..........................................LGFISDVDIFNHVKNTV.LK.YKA-.--LIDLARFNKNVIDPIKLTFDAKVYGKTFEEIIESECIRQIDKANNNHIEYFHQNLFSYAgNG.WYVPET....GFD..V--AN.DR............RKIYVEMKNKYNTMNSDTAQTTYIKMQDQLLRV----SNSTCMLVEVIAKQSQDRPWKITLDNQQY-----...EHDNIRRVSIDKFYDIVFGDPNAFMKLCKALPRILDDVISD...................
E4PTM4_MYCLG/7-203               ..........................................LDFIKQEDFEKHAIDTI.NQ.YRET.LKSINLKKFNRNIIDPIKLIFDKNIFNKEFKEIIELEISRQRDKTNNNVIGYFHQNIFKYI.KN.CKVPSQ....GWD..IIFQG.DE............NTYYVEMKNKHNTMNSVAASGIYMKMQNHLLNYDND-EKSICALVEVIAKHSQNIPWVMKIENQKLI----...GNRRIKRMSIDKFYEIVTGNKNSFKNLC-------------l..................
D6YSJ0_WADCW/5-205               ..........................................LGFIRDSDLYDHVKKTV.LN.YRF-.--DIDLKSFNKSLVDPIKLTFDSKIYQRSIESVVEDEVFRQLDKSNTNQIGYFHQNIFKYLhQG.WKVPEK....GFD..VI--N.EE............KKVFVEMKNKHNTMNSSSAKSTYIRMQNKILSC----PDSVCYLVEVIAKESQDIVWKISNDGSIL-----...SDPRIRRMSIDKFYGLVTNDPQSFKNLCSVLPSVLDDVVC-e..................
F3BBJ9_9FIRM/5-219               ..........................................LDFISEEDFKKHVRATI.MK.YGEK.LESYDLKRFNSNLIDPIKLIFDKSVYRTSWEEIVNNEIFRQRDKSNNNDIGYFHQNIFSYF.KG.CEVPQA....GWD..VIYRN.PDgiqmp..dgdivHTIYVEMKNKHNTMNSASSAKTYIKMQGQILED----DDCACLLVEAIAKKSQNIKWSTKVDGKNV-----...QHRLIRRVSMDQFYAILTGEEDAFYKMCMALPEVINSVVNE...................
E4TRM8_MARTH/6-209               ..........................................LDFVADEHLLKCVENLH.NS.YLKA.KENISKKTFYKNKVDTIKLIFDSKFNNLDEEEIIETEVLRQIDKSINNSIGTFHEELLGGI.DG.YEKGDL...sGF-..-DIKA.ED............DTLFADIKNKHNTMNSSSSESLFQK----LARYADDYKQAKCYWVQILAKKSFNEKWFAEINGKEY-----...SHSRVYKISGDQFYSLLTGQEDAFFKLYKNLPLAISDYL--gs.................
G6V5P1_STRPN/4-218               ..........................................LSFISEKD----VQLTI.DK.YREK.LQSFDLKRFNKNIVDPIKLIFDKSVYRSSWEQIISNEIFRQRDKSNNNDIGYFHQTIFKYI.EH.CRVPNNgedgGWD..VIFEN.TNgiimp..dgsrvSRVYVEMKNKHNTMNSASSGKTFIKIQNQLLQD----DDCECFLVKAIAKNSQNIKWEPKVDGQKM-----...GHKYIRRVSLDQFYSLVTGQKDALYNMCMVLPEVINKAVSE...................
H8BW37_CAMJU/7-212               ..........................................LEFINQRDFENHILNTV.KG.YQEV.LKKIDLRKFNENIIDPIKLTFDKTVFDYSFEKLIELELHRQRDKTNTNIIGYFHQNIFKYI.QK.CEAPKE....GWD..IIFKD.GM............ITYFIEMKNKHNTMNSSSASKTFIRMQNQLLKD----KECICALVEIIAKKSDNKPWVVSVDKKKQ----A...ECERLRRISIDKFYELVTKDKFAFQKLCLQIPITLNKVLKE...................
F4MP99_MYCML/7-215               ..........................................LDFIKQEDFEKHVIDTI.NQ.YRES.LKSINLKKFNRNIIDPIKLIFDKNIFNKEFKEIIELEISRQRDKTNNNVIGYFHQNIFKYI.KN.CKVPSQ....GWD..VIFQG.DE............NTYYVEMKNKHNTMNSVSASGIYMKMQNHLLNYDND-EKSICALVEVIAKHSQNIPWVMKIENQKLI----...GNRRIKRISIDKFYEIVTGNKNSFKNLCLQLPITLEKLVNE...................
H7K9F6_STRPN/4-218               ..........................................LSFISEKD----VQLTI.DK.YREK.LQSFDLKRFNKNIVDPIKLIFDKSVYRSSWEQIISNEIFRQRDKSNNNDIGYFHQTIFKYI.EH.CRVPNNgedgGWD..VIFEN.TNgiimp..dgsrvSRVYVEMKNKHNTMNSASSGKTFIKIQNQLLQD----DDCECFLVKAIAKNSQNIKWEPKVDGQKM-----...GHKYIRRVSLDQFYSLVTGQKDALYNMCMVLPEVINKAVSE...................
F7JFS2_9FIRM/3-110               .....................................dgdiv-----------------.--.----.-------------------------------------------------------------.--.------....---..-----.--............HTIYVEMKNKHNTMNSASSAKTYIKMQGQILED----DDCACLLVEAIAKKSQNIKWSTKVDGKNV-----...QHRLIRRVSMDQFYAILTGEEDAFYKMCMALPEVINSVVNE...................
G5EPA8_9MICC/6-224               ..........................................LTWIDNEELYKVTYETF.KKpFEKA.YDGFD-PYNSKNSVDPLGALFYMAALNISFDAWVDIERSRQIGKTLQNAVGTWHQRVLGLA.ED.WKDKGA...nGGV..FDLES.ISpiygyepypdkpKTIIAEVKNKFNTIKASDEKALHLKMYEQVSSRGK--KSTVAYLIQIIPKDGEKYNKPWVPSKAFE-----...-TPLVRHIDGYSAYNLVFKHNGALEELYNALPSILKDVIH-n..................
G1WDB9_9BACT/6-215               ..........................................LGFISNEAIFEHVQNTV.EQ.YRR-.--VIDLKAFNHNIIDPIKLTFDAKIYGQSIRQTIESECIRQIDKTNNNKIGYFHQYIFKYA.GGeWQVPDN....GERggFDVIN.DA............LGIYAEVKNKHNTMNSSSASATYLKMLDKIMRSGN---QACCYLVEAIAKQSQDLVWEPTIVQNGHK-ERY...SWPSIHKISMDRFYGVVFGDNHAFFKLCKALPQILDDVI--aa.................
F5W392_STAAU/6-218               ..........................................LSFITDEDLFECIEFLY.TE.YEKA.LEGIDFDKFFKNRIDTFKMTFDMGINNLSEQDWLAAELQRQVEKTITNHVGTFHEKLIGKI.EG.YTNYPV....GYD..YDVAK.DD............NTLFAEIKNKHNTLTGTHTKSLFQK----ICGYAEKYPDAICYYVRIIDTKSRNDIWEFRSGSIDENTREKprfSHPRVRIASGDQFYKIVTGEEDAFKQLAYNIPIALDDWIE-t..................
F3AQK1_9FIRM/5-219               ..........................................LDFISEEDFKKHVRATI.MK.YGEK.LESYDLKRFNSNLIDPIKLIFDKSVYRTSWEEIVNNEIFRQRDKSNNNDIGYFHQNIFSYF.KG.CEVPQA....GWD..VIYRN.PDgiqmp..dgdivHTIYVEMKNKHNTMNSASSAKTYIKMQGQILED----DDCACLLVEAIAKKSQNIKWSTKVDGKNV-----...QHRLIRRVSMDQFYAILTGEEDAFYKMCMALPEVINSVVNE...................
F2Y147_9PHYC/4-168               innqtensecgfclskycelidstihnillrpennvltydil-----------------.--.----.----------------------------DTEKLKTNKLLALKEKQRQMKVGEIWQEVLGNY.NG.CVNLKI....GHEtgLDILS.HT............KKFAIELKNRTNTDNASSKKSNLDK----LAKFKKHNPDYVCIYANINANTEQKT----------------...-----------------------------------------lqgsiqkllhdgveidhqi
T2S9_STAAU/6-218                 ..........................................LSFITDEDLFECIEFLY.TE.YEKA.LEGIDFDKFFKNRIDTFKMTFDMGINNLSEQDWLAAELQRQVEKTITNHVGTFHEKLIGKI.EG.YTNYPV....GYD..YDVAK.DD............NTLFAEIKNKHNTLTGTHTKSLFQK----ICGYAEKYPDAICYYVRIIDTKSRNDIWEFRSGSIDENTREKprfSHPRVRIASGDQFYKIVTGEEDAFKQLAYNIPIALDDWIE-t..................
E5XE96_9FIRM/5-219               ..........................................LDFISEEDFKKHVRATI.MK.YGEK.LESYDLKRFNSNLIDPIKLIFDKSVYRTSWEEIVNNEIFRQRDKSNNNDIGYFHQNIFSYF.KG.CEVPQA....GWD..VIYRN.PDgiqmp..dgdivHTIYVEMKNKHNTMNSASSAKTYIKMQGQILED----DDCACLLVEAIAKKSQNIKWSTKVDGKNV-----...QHRLIRRVSMDQFYAILTGEEDAFYKMCMALPEVINSVVNE...................
F0RE65_CELLC/6-209               ..........................................LSFISDEHLLSCIENLH.RS.YLKA.KVNVTKKKFYKNKIDTIKLTFDAKFNDLDEETLIKTEINRQIDKSINNSIGTFHEQILGGI.TG.FEIGNL...sGF-..-DIKA.TD............DTLFADIKNKHNTMNSSSAESLFQK----LAKYADTYKKANCYWVQILAKNSFNEKWFSEINGKEY-----...SHSRVYKISGDQFYKLLSGKENALFELYQVLPQAISDYLS-k..................
Q3D667_STRAG/4-222               ..........................................LSFISEEDFYNHVQLTI.DK.YGKK.LQSFDLKRFNKNIVDPIKLIFDKSVYRSSWEQIISNEIFRQRDKSNNNDIGYFHQTIFQYI.EH.CRVPNNgeegGWD..VIFEN.PNgitmp..dgsqvSRVYVEMKNKHNTMNSASSGKTFMKMQNQLLQD----DDCACFLVEAIAKNSQNIQWEPKVDGRKM-----...GHKYIRRVSLDQFYSLVTGQEDAFYNMCMVLPEVINKAVSE...................
D0GVW4_VIBMI/2-210               .....................................kafnr------ENLKNSIKESV.CQ.LYRAqTKKN---DLYRNTIDCFSASIDCVVQGITIDEWKREERQRQIQKTKQNAIGTLHEMIMSSI.DG.VTHYKVg..sGAL..VDIEC.EQ............KKLIAEIKNKHNTTKGNHKVAIYDDLEQRLASR----PDYTGYYVEILPPKKKVYNTPFTPSDNKTGQRRN...ANEKIRQIDGKSFYALLTGHNDAIRELYENLPDIVSEIINE...................
F7JFS3_9FIRM/5-115               ..........................................LDFISEEDFKKHVRATI.MK.YGEK.LESYDLKRFNSNLIDPIKLIFDKSVYRTSWEEIVNNEIFRQRDKSNNNDIGYFHQNIFLIS.KA.VKSHRQ....---..-----.--............-----------------------------------------------------------------------...-----------------------------------------agmlfteiqmeykcqmeil
D4M4D1_9FIRM/5-219               ..........................................LDFISEEDFKNHVRATI.MK.YGEK.LESYDLKRFNSNLIDPIKLIFDKSVYRTSWEEIVNNEIFRQRDKSNNNDIGYFHQNIFSYF.KG.CEVPQA....GWD..VIYRN.PDgiqms..egdvvHTLYIEMKNKHNTMNSASSAKTYIKMQSQILED----DDCACLLVEAIAKKSQNIKWSTKVDGKNV-----...QHRLIRRVSMDQFYAILTGEEDAFYKMCMALPEVINSVVNE...................
G5KZ23_STRSU/4-222               ..........................................LSFISEEDFYNHVQLTI.DK.YGEK.LKSFDLKRFNKNIVDPIKLIFDKSVYRSSWEQIISNEIFRQRDKSNNNDIGYFHQTIFKYI.EN.CRVPNNgeegGWD..VIFEN.TNgitmp..dgsrvSRVYVEMKNKHNTMNSASSGKTFIKMQNQLLQD----DDCACFLVEAIAKNSQNIKWEPKVDGQKM-----...GHKYIRRVSLDKFYALVTGEEDAFYKMCMVLPEVISKAVSE...................
C2L0T8_9FIRM/1-87                .........................................s-----------------.--.----.-------------------------------------------------------------.--.------....---..-----.--............-----------------ASGKTYIKMQNQLLND----DDCACFLVEAIAKKSQNIKWSTTVDGRSV-----...SHRRIRRVSMDQFYALVTGQEDAFYQICMVLPSIISQVIAE...................
E6UEZ3_RUMA7/4-222               ..........................................LSFISEEDFTKHVKKTI.EK.YGEK.LESFDLKRFNKNIIDPIKLIFDKTVYQASWEEIVCNEIFRQRDKSNNNDIGYFHQRIFQYI.AN.CRVPDNgkegGWD..VIFEN.PDgivvt..dgisvHTVYVEMKNKHNTMNSASAGKTFIKMQNQLLTD----DDCACFLVEAIAQRSQNIKWETTVDKKKV-----...GHKLIRRVSLDQFYALVTGQEDAFYQMCMVLPSIIQKAVDE...................
I0SCJ8_STRAP/5-223               ..........................................LDFISEEDFYNHVQATI.EK.YGEK.LKSFDLKRFNKNIIDPIKLIFDKTVYHNSWDEIIKSEIFRQRDKSNNNDIGYFHQRIFQYI.NN.CSVPDNghegGWD..VIYEN.PNgivlp..enskvSKIYVEMKNKHNTMNSASSGKTFIKMQNQLLQD----DNCACFLVEAIAKKSQNIKWEPKVDGKKM-----...GHKLIRRVSLDQFYALVTGQDDAFYQLCMVLPEVIENVVS-k..................
D1J7H6_MYCHP/343-548             ..........................................LDFIKQNDFEEHVKETI.KS.YNET.LKKIDLRKFNANVIDPIKLTFDKNLFKKTWEEVVESEIARQRDKSNTNAIGYFHQYMFKYI.KN.CIVPKT....GFD..VIYTDfNN............HKICVEMKNKHNTMNSSSSQKTYINMQNHIINH----SNDECFLVEVIAPKSRNIPWELSVNGNHC-----...KAENIRRVSIDKFYEIVTGESDAFYKLCKQLPITIEKLIG-e..................
#=GC seq_cons                    ..........................................LsFIoccDh.pcVptTl.pp.Ytct.Lpuh-lK+FN+NlIDPIKLlFDpslaptoaEcllpsElhRQpDKoNsNsIGYFHQpIFpYl.cs.hcVPps....GaD..V.hps.sp............pplalEhKNKHNTMNSuSuupsahKhQsplLpc....ccssCaLVEsIAK+SQNlpW.hplcspch........upphIRRlShDpFYtlVTGpcDAFhphChsLPpllpchlp....................
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