GenomeNet

Database: Pfam
Entry: RE_HaeII
LinkDB: RE_HaeII
Original site: RE_HaeII 
#=GF ID   RE_HaeII
#=GF AC   PF09554.8
#=GF DE   HaeII restriction endonuclease
#=GF AU   Coggill P
#=GF SE   Bateman A
#=GF GA   25.00 25.00;
#=GF TC   240.20 240.10;
#=GF NC   19.30 18.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11852561
#=GF RT   [Testing and isolation of high-purity restriction
#=GF RT   endonucleases]. 
#=GF RA   Puchkova LI, Ushakova TA, Mikhailova VK, Serov GD, Krivopalova
#=GF RA   GN, Repin VE; 
#=GF RL   Prikl Biokhim Mikrobiol. 2002;38:20-24.
#=GF RN   [2]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR019058;
#=GF CC   This family includes the HaeII (recognises and cleaves RGCGC^Y)
#=GF CC   restriction endonuclease.
#=GF SQ   14
#=GS A0A0A2FJY0_9PORP/6-343  AC A0A0A2FJY0.1
#=GS A0A0F5YJ57_9CYAN/1-173  AC A0A0F5YJ57.1
#=GS K9SQV9_9SYNE/7-342      AC K9SQV9.1
#=GS B1WXK7_CYAA5/1-260      AC B1WXK7.1
#=GS A0A0G1ZDU2_9BACT/8-343  AC A0A0G1ZDU2.1
#=GS R6DEP8_9BACE/7-342      AC R6DEP8.1
#=GS I3CC74_9GAMM/7-344      AC I3CC74.1
#=GS A0A0G1LHA2_9BACT/7-342  AC A0A0G1LHA2.1
#=GS A0YZ87_LYNSP/342-679    AC A0YZ87.1
#=GS E6KAK0_9BACT/7-342      AC E6KAK0.1
#=GS A0A0J9EYL5_9CYAN/8-181  AC A0A0J9EYL5.1
#=GS K9UB28_9CHRO/6-342      AC K9UB28.1
#=GS Q5F5D7_NEIG1/8-343      AC Q5F5D7.1
#=GS A7BSW8_9GAMM/8-347      AC A7BSW8.1
A0A0A2FJY0_9PORP/6-343             .AKLALDRLISKARVHLYKPIQIAEILHRDRVYGDI..DLVDLESYRNASKKWRDEVCLRFLGRTSSSSARYQDDLFNENAIPPSILRILGEENRAGGGIVEKYIYDCFEERFSQMSQGLR..YCKIHDKQSFLVKDFIDIFWNEPGLRRSIDKIYEIVVYALFSTLVESLKVKITIESDTDKQDLLHEFSDFAERVIGLSDQQSKITMSARINRVGVTNAADRGLDMWANFGMAIQIKHLSLTEELAENIVSSVSSDRIVIVCKDSEEKIIVSLLTQIGWKSKIQSIVTENDLVYWYNKALTGAFSKEIGDRVLSTLYHEILREFPA.TNFDDLNEFKKSRGY...........
A0A0F5YJ57_9CYAN/1-173             .-----------------------------------..-----------------------------------------------------------------------------------..-----------------------------------------------LNVTVKVELDINKLDILQEFEDFTQKVLSINSQNPSFTANAKFYRVGVTNAADRGLDMWANYGPAIQIKHLSLNESLAEGIVSHITADRIVIVCRDSEEKTIISLLNQIGWKSRIQSIITQSHLEAWYEKALRGSFRHILGAKLIQVLIEEIKYEFPS.SESNDLVSFMENRGY...........
K9SQV9_9SYNE/7-342                 .AKERLDSIVRKARVDMYKPIQIAEVLRRSRIQKDI..QILKQDTYQNPSIHWRNKVTRRLIGKVSTSSANYQHDIWNQKAMPPDLLAVLDHENKRTNGGVEYYIYLRFSERQNTVASVIT..FIETSLPENFDLSELLIKFTSQSEIRRSVDKAYEIVVYSLFETIVNALETTVKVSIPVKNTNLLAEFSDLTKVLLGLELGSNSWEVPAHIYRVGVTNAADRGLDMWANFGAAIQVKHLTLNQERAQSITNQVESDNVVIVCRDADARVIETIANQISWGSRVRGIVKESELIDWYERCLRGKFSKQLSKALLERLVYGFKSEFPQ.--ASTISDFLSERNY...........
B1WXK7_CYAA5/1-260                 .-----------------------------------..-------------------------------------------MPPEILKVLDDFNKKNLGIVEKYIYDKFKEKLGIISSIIQivLVGVSCPNNFQLDNLLSLFRQEAGIKRSIDKCYEIITYSLLETVVNQLEAEITVKIPEKNYLLLQEFSDLSKVLLNVNPDKPEWTELAHIYRVGVTNAADRGLDMWANFGPVIQVKHLTLNSAQVETIVDQIESDHIIIVCRDADASVISILMKQIGWGKRVRGIVKESQLIEWYNRCLRGKFSHQISQPLMNLLQKSFEEEFPE.--VTEIIEFYQERQY...........
A0A0G1ZDU2_9BACT/8-343             s-KKALDLVIRKSRVHLYKPIQIAEILYHHRTERGL..DLSDLQSYRNISKRWRDEVSLLLVGRRSTSSQKYQDNVFEANAMPPELLTKLGEINKKSKGVVEAYIYKALEARLSSVREVED..YIRKSTPDTFDLKKLVSIFQTTPGLRRSVDKMYEILVYALFTTIVRALKAQVTLEIGNKDKEILKDFERFIKMVLGIDAKQTRLVSPAALYRVGVTNASDRGLDIWANFGPAIQVKHLTLTPELMEDIADDITSDRIVIVCIDTERETIETLLKQVGWSERIQGVITINDLDDWYKLCLSKKYRANLGAKLLQDVGREFAAEFPS.--SKEIAPFMAKRGY...........
R6DEP8_9BACE/7-342                 .AKAALDNVIKKSRVHLYKPIQVAEILYRDRVFKDI..NLLSLEDYRTKSKKWRDEVSIVLLGRVSTSSARFQDDLFNDNATPPAVLDVLGRENRRTNGAVEAYIYSKFDNKHEQLSNALA..YCLDASVETFEVKKFIDSFWNEPGLKRSLDKIYEIIVYALFSTLVEAMNLEVEVTVKEDAYPLLKEFEDFTQKVMCLDCSTPQHIQEARVYRVGVTNAADRGLDMYSNWGPAIQIKHLSLDISLAESIVNSVSSDRIVIVCKDAEKDVIVSLLSQIGWRSHIQSIVTENDLIKWYEKALRGSYSEQLGEKLLYCLASEIAEEFPS.VD-------------ytpeiikkrhy
I3CC74_9GAMM/7-344                 .AKYALDKIIDKARVHFYKPIQIAEILYRDRVIQDI..NLIDLATYRISSKKWRDIICLQFLGRTSASSARYQDDLFNDNAIPPPILACLGEENRIHQGIVEAYIYHRFAQRIGQLSTGLD..YCQTHDANTFQLREFLALFWHEAGLRRSIDKVYEIIVYALFSTLVEVLEVNIDVSINTEKKTILQDFEDFTEAVIQLNAKKTHYRLKARINRTGVTNAADRGLDMWANFGLAIQVKHLSLTEELAENIVTAISADRIVIVCKDAEKKIIVSLLNQMGWKSKIQSILVESDLIRWYEKALRGEFANTIAHHILNKLSAEIQLEFPS.TDKTEFMAFLKTRGY...........
A0A0G1LHA2_9BACT/7-342             s-KIALDTIIRKSRVHFYKPIQIAEILYYHRTQKGL..NLKNLETYRNISKRWRDEVSIRLVGRKSTSSQKYQDNVFEQNAMPPNLLAALGEANKNGGGFIEAYIYKSLRVKLGSVHKVRK..YIKNSTEDAFSIQGLVDRFVKTPGLRRSIDKMYEIGVHGLFATIVRALQAQITLEIKNEDKDILIDFERFIKMVLGINAKQTKLILPAALYRVGVTNAADRGLDMWANFGAAVQVKHLTLTPETVEEIAENIAADRIVIVCLDAEKKSIESLLKQVGWGERIQGIITLNDLDEWYRLCLNKKYRDRLGGTLLKDLLREFDAEFPS.--SAEITPFLRERGY...........
A0YZ87_LYNSP/342-679               .AKDALDNIINKARVHFYKPIQVAEILYHHRVFDDL..TLSNLNTYRKSSKKWRDIICKRFLGRITTSSSRYQDNLFEQNATPPEVLMVLGEENKSKLGIVEAYIYRKFIERYSQMTSGLA..YCMKSDIENFKLTEFIGQFQNNPGLKRSIDKIYEIVVYALFKVLIEELNVTVKVQLDFNKLDLLKEFEDFTQKVLSINSQNPSFTASAKFYRVGVTNAADRGLDMWANYGSAVQIKYLSLNEGLAEGIVSNITADRIVIVCRDSEERTIVSLLNQIGWKSRIQSIITQSHLEAWYEKALRGSFRNILGARLIEILIEEIKYEFPS.SESNDLVSFMEEREY...........
E6KAK0_9BACT/7-342                 .AKAALDTVIKKSRVHLYKPIQIAEILYRDRIYKDI..NLLSLEDYRTKSKKWRDKVSIVLLGRVSTSSARFQDDLFNDNATPPAVLDVLGHENRRTNGAVEAYIYNKFDYKHEQLSNALS..YCLDADTESFEVKKFIDSFWNEPGLKRSLDKIYEIIVYALFSTLVDAMNLKVEVTVGEEAYPLLKEFEEFTKKIMCLDCSTPQHIQEAKVYRVGVTNAADRGLDMYSNWGPAIQIKHLSLDLTIAENIVNSVSSDRIVIVCKDAEKDVIVSLLTQIGWRSHIQSIVTENDLVTWYEKALRGSYSDMLGEKLLFCLANEIAEEFPS.VD--STPEIIKERH-y..........
A0A0J9EYL5_9CYAN/8-181             .AKNALDNIINKARVHFYKPIQVAEILYHHRVFDDL..TLADINTYRTASKRWRDVICKRFLGRITNSSSRYQDNLFEQNATPPEVLMLLGEENKNKSGIVEAYIYRKFIERYSQMTSGLA..YCMKSDIENFELTEFIGQFQNNPGLKRSIDKIYEIVVYALFKVLIEELNVTVKVE------------------------------------------------------------------------------------------------------------------------------------------------------.---------------l..........
K9UB28_9CHRO/6-342                 .AKAALDRIIKISRVHLYKPIQIAEILYRDRVHRDL..DLSDLNTYRNTSKAWRNLITDRFVGRSSSSSAEYQEALFTK-AMPPQTLVILGEENRLKGGIIEAYIYRRFAERFTQLSSALN..YYDTHSTTDFEVREFIDLFWSEPGLRRSIDKVYEIVVYSLFSVLVEALEVTITISINESKLGLLEEFSDFTEMVIGLTQDKYLLNLPAKIYRVGVTNAADRGLDMYANFGMAIQIKHLSLTPELAENIVGSVTADRIVIVCRDSEQALIVSLLNQIGWKAKIQSIITENNLQGWYEKALRGSFSAAIGKRILLTLKEQIIAEFPA.SDNRDFTEFYESRNY...........
Q5F5D7_NEIG1/8-343                 .AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...........
A7BSW8_9GAMM/8-347                 .AKNALDSIIKKSRVHLYKPIQIAEILYNARTQPDLeiELSNLESYRTRSKQWRDVVCIQFLGRVSTSSAKFQDNLFEENAMPPHLLSILGVENQKNNGIVEAYIYQAFEDKHLQLDNALN..YCLTSTKENFKLGEFLNQFWSEAGLKRSLDKIFEMVVYSLFEVLTTSIHVKIDIYYNTNNTDILNEFSEFSDKVLNLTASTNRKTLDAHFHRVGVTNAADRGLDMYANFGSVVQIKHLSLDKDLAENIVTSLTANRIIIVCKSAEEEVINSLLNQIGWQARIQSIITIDELIDWYDKALIGKYSELLGEKVIATLSEEIKNEFPS.VGNNDFQNFKKNRGY...........
#=GC seq_cons                      .AKtALDplIcKuRVHhYKPIQIAEILY+cRs.cDl..sL.sLpoYRstSK+WRD.lshphlGRhSoSSu+aQDsLFppNAhPPplLslLGcEN+pssGhVEAYIYcpFtp+hsQlosuLs..YshsushpsFplpcFls.FhspPGL+RSlDKlYEIlVYuLFpsLVcsLplplplplspcphslLpEFpDFochVlslssppsphphsA+lYRVGVTNAADRGLDMWANFGsAIQlKHLSLs.pLAEsIVsslouDRIVIVC+DuEcclIsSLLsQIGWpu+IQuIlTps-L.pWY-KALRGpasp.lGp+LLpsLhpEIttEFPu.stss-h.pFhppRsY...........
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