GenomeNet

Database: Pfam
Entry: RE_HaeII
LinkDB: RE_HaeII
Original site: RE_HaeII 
#=GF ID   RE_HaeII
#=GF AC   PF09554.6
#=GF DE   HaeII restriction endonuclease
#=GF AU   Coggill P
#=GF SE   Bateman A
#=GF GA   25.00 25.00;
#=GF TC   91.90 91.60;
#=GF NC   20.20 19.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11852561
#=GF RT   [Testing and isolation of high-purity restriction
#=GF RT   endonucleases]. 
#=GF RA   Puchkova LI, Ushakova TA, Mikhailova VK, Serov GD, Krivopalova
#=GF RA   GN, Repin VE; 
#=GF RL   Prikl Biokhim Mikrobiol. 2002;38:20-24.
#=GF RN   [2]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR019058;
#=GF CC   This family includes the HaeII (recognises and cleaves RGCGC^Y)
#=GF CC   restriction endonuclease.
#=GF SQ   39
#=GS D6H9Y8_NEIGO/3-271    AC D6H9Y8.1
#=GS I4FGS1_MICAE/7-342    AC I4FGS1.1
#=GS E6KAK0_9BACT/7-342    AC E6KAK0.1
#=GS D1DL07_NEIGO/8-343    AC D1DL07.1
#=GS Q5F5D7_NEIG1/8-343    AC Q5F5D7.1
#=GS U7QAW8_9CYAN/8-345    AC U7QAW8.1
#=GS K9UB28_9CHRO/6-342    AC K9UB28.1
#=GS A7BSW8_9GAMM/8-347    AC A7BSW8.1
#=GS T2B1_NEIGO/8-343      AC Q50973.2
#=GS E8SMT7_NEIGO/8-343    AC E8SMT7.1
#=GS D1DSS4_NEIGO/8-343    AC D1DSS4.1
#=GS C1HUQ0_NEIGO/8-343    AC C1HUQ0.1
#=GS D1EBK0_NEIGO/8-343    AC D1EBK0.1
#=GS I3CC74_9GAMM/7-344    AC I3CC74.1
#=GS N2BN65_9HELI/5-338    AC N2BN65.1
#=GS E7AH90_HAEIF/7-344    AC E7AH90.1
#=GS A3IJ86_9CHRO/8-199    AC A3IJ86.1
#=GS C6S4J2_NEIML/8-343    AC C6S4J2.1
#=GS A0YZ87_LYNSP/342-679  AC A0YZ87.1
#=GS V8C922_9HELI/13-346   AC V8C922.1
#=GS D1DZQ0_NEIGO/8-343    AC D1DZQ0.1
#=GS K9SQV9_9SYNE/7-342    AC K9SQV9.1
#=GS F2C206_HAEAE/7-344    AC F2C206.1
#=GS D1D894_NEIGO/8-343    AC D1D894.1
#=GS A4N0A4_HAEIF/7-344    AC A4N0A4.1
#=GS R6DEP8_9BACE/7-342    AC R6DEP8.1
#=GS T2H2_HAEAE/7-344      AC O30869.1
#=GS Q4QK84_HAEI8/7-344    AC Q4QK84.1
#=GS I4HC46_MICAE/7-342    AC I4HC46.1
#=GS W4PB60_9BACE/6-343    AC W4PB60.1
#=GS B1WXK7_CYAA5/1-260    AC B1WXK7.1
#=GS W4PH33_9BACE/9-346    AC W4PH33.1
#=GS D6JJ57_NEIGO/8-343    AC D6JJ57.1
#=GS D1ECI0_NEIGO/8-343    AC D1ECI0.1
#=GS B4RQP2_NEIG2/8-343    AC B4RQP2.1
#=GS F0F9N4_9BACT/3-86     AC F0F9N4.1
#=GS D1DEK7_NEIGO/8-343    AC D1DEK7.1
#=GS D1DLE2_NEIGO/8-343    AC D1DLE2.1
#=GS E2PD56_NEIPO/8-343    AC E2PD56.1
D6H9Y8_NEIGO/3-271               nskiic-----------------------------------..--------------------------------------LKKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
I4FGS1_MICAE/7-342               ......AKMRLDSIIAKARIDLYKPIQIAEVLRKSRLEKNI..KILDLKTYQNQSIRWRDEVTIRLLNKVSTSSARYQHDVWSTTAMSPELLEILDRENKRTRGGVERYIYLKFSERQATVSSLID..YIDSQNEKSFDLKYLLYEFSAKAGIRRSIDKAYEIIAYSLFETIVVSLEAEITMSIPSIKQDLLNEFSDLAKALLGLDKNQNKRVFKAHIYRVGVTNAADRGLDMWANFGIAIQIKHLTLDEEIAQNIIDKVESDHIVIVCRDAHADVIKIIAQQISWGQRVRGIILESELINWYDRCLRGEFSNLLAKPLLQYLSDNFRKEFPQ.--SIALIDFLEERKY...................
E6KAK0_9BACT/7-342               ......AKAALDTVIKKSRVHLYKPIQIAEILYRDRIYKDI..NLLSLEDYRTKSKKWRDKVSIVLLGRVSTSSARFQDDLFNDNATPPAVLDVLGHENRRTNGAVEAYIYNKFDYKHEQLSNALS..YCLDADTESFEVKKFIDSFWNEPGLKRSLDKIYEIIVYALFSTLVDAMNLKVEVTVGEEAYPLLKEFEEFTKKIMCLDCSTPQHIQEAKVYRVGVTNAADRGLDMYSNWGPAIQIKHLSLDLTIAENIVNSVSSDRIVIVCKDAEKDVIVSLLTQIGWRSHIQSIVTENDLVTWYEKALRGSYSDMLGEKLLFCLANEIAEEFPS.VD--STPEIIKERH-y..................
D1DL07_NEIGO/8-343               ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
Q5F5D7_NEIG1/8-343               ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
U7QAW8_9CYAN/8-345               ......AKDALDNIINKARVHLYKPIQVAEILYHHRVFDDL..TLSNLNTYRKSSKKWRDIICKRFLGRITTSSSRYQDNLFDKNATPPEVLMVLGEDNKSKSGIVEAYIYRKFIERYSQMTSGLA..YCMKSDIENFKLTEFIGQFQNNPGLKRSIDKIYEIVVYALFKVLIEELNVTVKVQLDFNKLDLLKEFEEFTQKVLSINSQNPSFTASAKFYRVGVTNAADRGLDMWANYGPAVQIKYLSLNESLAEGIVSNITADRIVIVCRDSEERTIVSLLNQIGWKSRIQSIITQSHLEAWYEKALRGSFRNILGARLIEILIEEIKYEFPS.SESNDLVSFMEEREY...................
K9UB28_9CHRO/6-342               ......AKAALDRIIKISRVHLYKPIQIAEILYRDRVHRDL..DLSDLNTYRNTSKAWRNLITDRFVGRSSSSSAEYQEALFTK-AMPPQTLVILGEENRLKGGIIEAYIYRRFAERFTQLSSALN..YYDTHSTTDFEVREFIDLFWSEPGLRRSIDKVYEIVVYSLFSVLVEALEVTITISINESKLGLLEEFSDFTEMVIGLTQDKYLLNLPAKIYRVGVTNAADRGLDMYANFGMAIQIKHLSLTPELAENIVGSVTADRIVIVCRDSEQALIVSLLNQIGWKAKIQSIITENNLQGWYEKALRGSFSAAIGKRILLTLKEQIIAEFPA.SDNRDFTEFYESRNY...................
A7BSW8_9GAMM/8-347               ......AKNALDSIIKKSRVHLYKPIQIAEILYNARTQPDLeiELSNLESYRTRSKQWRDVVCIQFLGRVSTSSAKFQDNLFEENAMPPHLLSILGVENQKNNGIVEAYIYQAFEDKHLQLDNALN..YCLTSTKENFKLGEFLNQFWSEAGLKRSLDKIFEMVVYSLFEVLTTSIHVKIDIYYNTNNTDILNEFSEFSDKVLNLTASTNRKTLDAHFHRVGVTNAADRGLDMYANFGSVVQIKHLSLDKDLAENIVTSLTANRIIIVCKSAEEEVINSLLNQIGWQARIQSIITIDELIDWYDKALIGKYSELLGEKVIATLSEEIKNEFPS.VGNNDFQNFKKNRGY...................
T2B1_NEIGO/8-343                 ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSERLA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
E8SMT7_NEIGO/8-343               ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
D1DSS4_NEIGO/8-343               ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
C1HUQ0_NEIGO/8-343               ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
D1EBK0_NEIGO/8-343               ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
I3CC74_9GAMM/7-344               ......AKYALDKIIDKARVHFYKPIQIAEILYRDRVIQDI..NLIDLATYRISSKKWRDIICLQFLGRTSASSARYQDDLFNDNAIPPPILACLGEENRIHQGIVEAYIYHRFAQRIGQLSTGLD..YCQTHDANTFQLREFLALFWHEAGLRRSIDKVYEIIVYALFSTLVEVLEVNIDVSINTEKKTILQDFEDFTEAVIQLNAKKTHYRLKARINRTGVTNAADRGLDMWANFGLAIQVKHLSLTEELAENIVTAISADRIVIVCKDAEKKIIVSLLNQMGWKSKIQSILVESDLIRWYEKALRGEFANTIAHHILNKLSAEIQLEFPS.TDKTEFMAFLKTRGY...................
N2BN65_9HELI/5-338               ......AKNALDKVIIKSRIHFYKPIQIAEILYRDRIFGDI..DLSNLETYRTKSKAWRDEVCIALLGRISTSSAKFQDDLFN--AIPPKIIAELGKFNREHNGVVESYIYNKFIGKYIQLNNALN..YCLNTDKAHFEISHFINLFWYEAGLKRSLDKVYEIITHSLFDVLAQTLELSITLSINQDKLNILKEFEDFAQSVICLDSNNLFITQKAHIYRVGVTNAADRGLDMYANWGVAIQIKHLSLDSELAESIVSHIQSDRIVIVCKEAEKSVILSLLTQIGWKNKIQSIITESHLIAWYEKAMRGRYANLLGDKLLETLCLEITEEFPS.--VKELPEILKNRYY...................
E7AH90_HAEIF/7-344               ......AKESLDKIIKKARVHLYKPIQIAEILYQDRVNKNI..NLLDKETYRNISKKWRDVICIRFLGRVSTSSAKYQDDLFNDNAMPPKHLNILGEMNRKTNGGVESYIYKKFFERFNQMSSALE..YSYSRTPDNFHLSEFLALFWLEPGLKRSIDKVYEIVVYALFSSLIEALGVKVKIDLDLSNIDLLKEFEDFTRQIISLDSENTSLELNAKINRVGVTNASDRGLDMWANFGMAIQIKHLSLTEELAENIVSSVSSDRIVIVCKESEEKLILSLLNQIGWRSKIQSIITEADLIKWYDKALRGKSAYLVGSKILEHIRNEISLEFPA.TDIVDFNHFFHEREY...................
A3IJ86_9CHRO/8-199               ......AKMKLDKIINKSRTRFYKPIQIAEVLYHSRVDNNI..DTSNKEDYRIKSKLWRDQVTNRLLHQSSTSSSRFQDDIWNDNAMPPEMLKVLDDFNKKNSGIVEKYIYDKFKEKLGVISSIIQifLVGLSCPNNFQLDNLLSLFRQEAGIKRSIDKCYEIITYSLLETVINQLEAEIE--------------------------------------------------------------------------------------------------------------------------------------------------------.---------------efpevteiiefyqerqyte
C6S4J2_NEIML/8-343               ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAMPPEKLAVLGTLNRQLDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIVSIPQNGH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLIRWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQSRGY...................
A0YZ87_LYNSP/342-679             ......AKDALDNIINKARVHFYKPIQVAEILYHHRVFDDL..TLSNLNTYRKSSKKWRDIICKRFLGRITTSSSRYQDNLFEQNATPPEVLMVLGEENKSKLGIVEAYIYRKFIERYSQMTSGLA..YCMKSDIENFKLTEFIGQFQNNPGLKRSIDKIYEIVVYALFKVLIEELNVTVKVQLDFNKLDLLKEFEDFTQKVLSINSQNPSFTASAKFYRVGVTNAADRGLDMWANYGSAVQIKYLSLNEGLAEGIVSNITADRIVIVCRDSEERTIVSLLNQIGWKSRIQSIITQSHLEAWYEKALRGSFRNILGARLIEILIEEIKYEFPS.SESNDLVSFMEEREY...................
V8C922_9HELI/13-346              ......AKTALDVVIKKSRIHLYKPIQIAEILYRDRVFGDI..DLARLETYRNKSKVWRDEMCIALLGRVSTSSAKFQDDLFN--AIPPHLLSALGAHNKNHNGIIEAYIYNQFLHKYTQLKNALS..YCINANKETFQIKEFIDLFWREAGLKRSIDKIYEIIVYALFESITKALEITITVNMNPQKAPLLEEFSDFAKSVIGIDETTLKSTQNAHFYRLGVTNAADRGLDMYANFGAAVQIKHLSLEVQMAQNITQGVRSDKIIIVCKEAEKDIISSLLAQIGYASKIVSIITESDLTKWYEKALRGKYANKLGDEVLKNLQVEIMEEFPP.--TKDLPKMLTDRHY...................
D1DZQ0_NEIGO/8-343               ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
K9SQV9_9SYNE/7-342               ......AKERLDSIVRKARVDMYKPIQIAEVLRRSRIQKDI..QILKQDTYQNPSIHWRNKVTRRLIGKVSTSSANYQHDIWNQKAMPPDLLAVLDHENKRTNGGVEYYIYLRFSERQNTVASVIT..FIETSLPENFDLSELLIKFTSQSEIRRSVDKAYEIVVYSLFETIVNALETTVKVSIPVKNTNLLAEFSDLTKVLLGLELGSNSWEVPAHIYRVGVTNAADRGLDMWANFGAAIQVKHLTLNQERAQSITNQVESDNVVIVCRDADARVIETIANQISWGSRVRGIVKESELIDWYERCLRGKFSKQLSKALLERLVYGFKSEFPQ.--ASTISDFLSERNY...................
F2C206_HAEAE/7-344               ......AKESLDKIIKKARVHLYKPIQIAEILYQDRVNKNI..NLLDKETYRNISKKWRDVICIRFLGRVSTSSAKYQDDLFNDNAMPPKHLNILGEMNRKTNGGVESYIYKKFFERFNQMSSALE..YSYSRTPDNFHLSEFLALFWLEPGLKRSIDKVYEIVVYALFSSLIEALGVKVKIDLDLSNIDLLKEFEDFTRQIISLDSENTSLELNAKINRVGVTNASDRGLDMWANFGMAIQIKHLSLTEELAENIVSSVSSDRIVIVCKESEEKLILSLLNQIGWRSKIQSIITEADLIKWYDKALRGKSAYLVGSKILEHIRNEISLEFPA.TDIVDFNHFFHEREY...................
D1D894_NEIGO/8-343               ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
A4N0A4_HAEIF/7-344               ......AKESLDKIIKKARVHLYKPIQIAEILYQDRVNKNI..NLLDKETYRNISKKWRDVICIRFLGRVSTSSAKYQDDLFNDNAMPPKHLNILGEMNRKTNGGVESYIYKKFFERFNQMSSALE..YSYSRTPDNFHLSEFLALFWLEPGLKRSIDKVYEIVVYALFSSLIEALGVKVKIDLDLSNIDLLKEFEDFTRQIISLDSENTSLELNAKINRVGVTNASDRGLDMWANFGMAIQIKHLSLTEELAENIVSSVSSDRIVIVCKESEEKLILSLLNQIGWRSKIQSIITEADLIKWYDKALRGKSAYLVGSKILEHIRNEISLEFPA.TDIVDFNHFFHEREY...................
R6DEP8_9BACE/7-342               ......AKAALDNVIKKSRVHLYKPIQVAEILYRDRVFKDI..NLLSLEDYRTKSKKWRDEVSIVLLGRVSTSSARFQDDLFNDNATPPAVLDVLGRENRRTNGAVEAYIYSKFDNKHEQLSNALA..YCLDASVETFEVKKFIDSFWNEPGLKRSLDKIYEIIVYALFSTLVEAMNLEVEVTVKEDAYPLLKEFEDFTQKVMCLDCSTPQHIQEARVYRVGVTNAADRGLDMYSNWGPAIQIKHLSLDISLAESIVNSVSSDRIVIVCKDAEKDVIVSLLSQIGWRSHIQSIVTENDLIKWYEKALRGSYSEQLGEKLLYCLASEIAEEFPS.VD-------------ytpeiikkrhy........
T2H2_HAEAE/7-344                 ......AKESLDKIIKKARVHLYKPIQIAEILYQDRVNKNI..NLLDKETYRNISKKWRDVICIRFLGRVSTSSAKYQDDLFNDNAMPPKHLNILGEMNRKTNGGVESYIYKKFFERFNQMSSALE..YSYSRTPDNFHLSEFLALFWLEPGLKRSIDKVYEIVVYALFSSLIEALGVKVKIDLDLSNIDLLKEFEDFTRQIISLDSENTSLELNAKINRVGVTNASDRGLDMWANFGMAIQIKHLSLTEELAENIVSSVSSDRIVIVCKESEEKLILSLLNQIGWRSKIQSIITEADLIKWYDKALRGKSAYLVGSKILEHIRNEINLEFPA.TDIVDFNHFFHEREY...................
Q4QK84_HAEI8/7-344               ......AKESLDKIIKKARVHLYKPIQIAEILYQDRVNKNI..NLLDKETYRNISKKWRDVICIRFLGRVSTSSAKYQDDLFNDNAMPPKHLNILGEMNRKTNGGVESYIYKKFFERFNQMSSALE..YSYSRTPDNFHLSEFLALFWLEPGLKRSIDKVYEIVVYALFSSLIEALGVKVKIDLDLSNIDLLKEFEDFTRQIISLDSENTSLELNAKINRVGVTNASDRGLDMWANFGMAIQIKHLSLTEELAENIVSSVSSDRIVIVCKESEEKLILSLLNQIGWRSKIQSIITEADLIKWYDKALRGKSAYLVGSKILEHIRNEISLEFPA.TDIVDFNHFFHECEY...................
I4HC46_MICAE/7-342               ......AKMRLDSIIAKARIDLYKPIQIAEVLRKSRLEKNI..KILDLKTYQNQSIRWRDEVTIRLLNKVSTSSARYQHDVWSTTAMSPELLEILDRENKRTRGGVERYIYLKFSERQATVSSLID..YIDSQNEKSFDLKYLLDEFSAKAGIRRSIDKAYEIIAYSLFETIVVSLEAEITMSIPSIKQDLLNEFSDLAKALLGLDKNQNKRVFKAHIYRVGVTNAADRGLDMWANFGIAIQIKHLTLDEEIAQNIIDKVESDHIVIVCRDAHADVIKIIAQQISWGQRVRGIILESELINWYNRCLRGEFSNLLAKPLLQYLSDNFRKEFPQ.--SIALIDFLEERKY...................
W4PB60_9BACE/6-343               ......AKQALDKIISKGRVHLYKPIQIAEILYRDRVRGDI..DLADLDTYRNASKRWRDVVCLRFLGRTSTSSARYQDDVFNENAVPPSVLEVLGAENRQNNGVVEKYIYDRFEQRFSQMSSGLD..YCSTHDKSNFQVIEFINLFWNEPGLRRSVDKIYEIVVYALFSALIECLKVKVTVEADKAKQKLLEEFSDFSERVIGLSKERSTVTVNARINRVGVTNAADRGLDMWANFGMAIQIKHLSLTEELAENIVSSVSSDRIVIVCKDSEEKLIVSLLTQIGWKSRIQSIVTEDDLILWYEKALRGTFAEEIGDKVLSTLYDEILLEFPA.TNSDDFNDFKHSRGY...................
B1WXK7_CYAA5/1-260               ......-----------------------------------..-------------------------------------------MPPEILKVLDDFNKKNLGIVEKYIYDKFKEKLGIISSIIQivLVGVSCPNNFQLDNLLSLFRQEAGIKRSIDKCYEIITYSLLETVVNQLEAEITVKIPEKNYLLLQEFSDLSKVLLNVNPDKPEWTELAHIYRVGVTNAADRGLDMWANFGPVIQVKHLTLNSAQVETIVDQIESDHIIIVCRDADASVISILMKQIGWGKRVRGIVKESQLIEWYNRCLRGKFSHQISQPLMNLLQKSFEEEFPE.--VTEIIEFYQERQY...................
W4PH33_9BACE/9-346               ......AKQALDKIISKGRVHLYKPIQIAEILYRDRVRGDI..DLADLDTYRNASKRWRDVVCLRFLGRTSTSSARYQDDVFNENAVPPSVLEVLGAENRQNNGVVEKYIYDRFEQRFSQMSSGLD..YCSTHDKSNFQVIEFINLFWNEPGLRRSVDKIYEIVVYALFSALIECLKVKVTVEADKAKQKLLEEFSDFSERVIGLSKERSTVTVNARINRVGVTNAADRGLDMWANFGMAIQIKHLSLTEELAENIVSSVSSDRIVIVCKDSEEKLIVSLLTQIGWKSRIQSIVTEDDLILWYEKALRGTFAEEIGDKVLSTLYDEILLEFPA.TNSDDFNDFKHSRGY...................
D6JJ57_NEIGO/8-343               ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
D1ECI0_NEIGO/8-343               ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
B4RQP2_NEIG2/8-343               ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
F0F9N4_9BACT/3-86                .....f-----------------------------------..-----------------------------------------------------------------------------------..---------------------------------------------------------------------------------------------------------------------------------------NIYLVCKDAEEKTIVSLLNQIGWKSKIQNIVTEKELIKWYKKALTGTYSELLASKLLNTLSEEMQLEFPS.LDA--LPDALTQR--hy.................
D1DEK7_NEIGO/8-343               ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
D1DLE2_NEIGO/8-343               ......AKEALDGIIKKSRVHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAIPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIITMPKNEH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
E2PD56_NEIPO/8-343               ......AKEALDGIIKKSRIHLYKPIQIAEILYHDRCIKQL..DFLNLDTYRNQSKRWRDEICRRFLGRISTSSAKFQDNLFEKNAMPPEKLAVLGTLNRQSDGGVESYIYKQFFNRFSQMSEALA..YVGNTDRYSFQLSEFLNLFWLEPGLKRSIDKIYEIVVYALFDALVSELGITVSIDFPKENLFLWEEYQDFAEKIVSIPQNGH-LKLPAKIHRVGVTNAADRGLDMWSNFGLAIQVKHLSLDEELAEDIVSSISADRIVIVCKKAEQSVIVSLLTQIGWKSRIQNIVTEDDLISWYEKALRGQYP--IAEALLENIKTEIMREFPAvNEANEFLDFAQNRGY...................
#=GC seq_cons                    ......AK-ALDsIIKKuRVHLYKPIQIAEILY+DRshKpl..chLsL-TYRNpSK+WRDpIChRFLGRlSTSSAKaQDsLFpcNAhPP-hLsVLGphNRposGGVEuYIY+pFhpRFuQMSpALs..YsssoDc.sFpLSEFLsLFWhEPGLKRSIDKIYEIVVYALF-uLVspLslsVoI-hsppNl.LhcEapDFuc+lIohspspp.lcLsAKIaRVGVTNAADRGLDMWuNFGhAIQlKHLSL-EELAEsIVSSlSuDRIVIVCKcAEpsVIVSLLsQIGWKSRIQsIVTEsDLIsWYEKALRGpas..lu-tLLEslpsEIhcEFPA.s-us-Fh-FhpsRtY...................
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