GenomeNet

Database: Pfam
Entry: RE_HindVP
LinkDB: RE_HindVP
Original site: RE_HindVP 
#=GF ID   RE_HindVP
#=GF AC   PF09519.8
#=GF DE   HindVP restriction endonuclease
#=GF AU   Bateman A
#=GF SE   Bateman A
#=GF GA   25.00 25.00;
#=GF TC   94.40 65.40;
#=GF NC   18.40 18.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR019044;
#=GF CC   This family includes the HindVP (recognises GRCGYC bu the
#=GF CC   cleavage site is unknown) restriction endonucleases.
#=GF SQ   27
#=GS B6GAI4_9ACTN/2-178       AC B6GAI4.1
#=GS K1LVP4_9BACT/24-357      AC K1LVP4.1
#=GS R7HRJ4_9BACT/1-140       AC R7HRJ4.1
#=GS A0A077DF45_9BURK/22-350  AC A0A077DF45.1
#=GS A0A0M2Q267_PROHO/24-349  AC A0A0M2Q267.1
#=GS A0A087ZTH5_APIME/24-347  AC A0A087ZTH5.1
#=GS K9YGZ7_HALP7/27-362      AC K9YGZ7.1
#=GS K9W1X6_9CYAN/27-361      AC K9W1X6.1
#=GS I3WFP7_BIFBI/46-384      AC I3WFP7.1
#=GS K9V6T6_9CYAN/28-362      AC K9V6T6.1
#=GS K9RQK0_SYNP3/22-361      AC K9RQK0.1
#=GS Q4CAI1_CROWT/75-205      AC Q4CAI1.1
#=GS K9ZBE3_ANACC/26-359      AC K9ZBE3.1
#=GS A0A075JTS7_9BACI/24-360  AC A0A075JTS7.1
#=GS T2D5_HAEIN/95-333        AC P44999.1
#=GS T2D5_HAEIN/35-99         AC P44999.1
#=GS A7BNK2_9GAMM/1-80        AC A7BNK2.1
#=GS A7C1H2_9GAMM/29-360      AC A7C1H2.1
#=GS D5EYH7_PRER2/36-367      AC D5EYH7.1
#=GS D4ZXW4_ARTPN/27-360      AC D4ZXW4.1
#=GS R7HTQ3_9BACT/35-149      AC R7HTQ3.1
#=GS R7JVX4_9CLOT/19-348      AC R7JVX4.1
#=GS Q4CAI1_CROWT/27-78       AC Q4CAI1.1
#=GS R6RHP0_9FIRM/19-349      AC R6RHP0.1
#=GS C0EI87_9FIRM/1-313       AC C0EI87.1
#=GS B1WX28_CYAA5/25-357      AC B1WX28.1
#=GS R5ACP9_9FIRM/23-350      AC R5ACP9.1
B6GAI4_9ACTN/2-178                  .dy----------------------------...-----..----------------..-----------------------.------------....--------------------------------------------------------..--------------..-EWKNETFMLKHLQCVISAAEEIAL......KGIPSQAPFALTAIWRTKGQASILDTECFDAFVWSDMAFVQLFIDAARRNDKP....-PISRPSRSLIWLIKALFDYSAQGIVTFEKTRSEITYGAQTDKAGSFSGESLSPFLQGNTFLHPRIPDVDYSKIVDPSGIDLLKPERRLDGALVSA----ktl.
K1LVP4_9BACT/24-357                 ...WGKNQFNSSFPAGLTNFLASKNLDNVYL...YLDKE..LKVKHKKISAKELYGI..EPNSDDLFFSFESPYTPYQQLVI.GTLPRVDLVTQL....RSNGQCLRPIEVKLTALPDNSTCNLSEEYYGCEIVIRPDTIVYLACSIASNFKDNK..KELASLIGNKFEKI..SDWTDGASVWSHITEMIAAIDRVIL......SVLDKQEPLLMQPIWKTNGKSPKLSDNCLDVFIWSNFAFTQLFVDVARGELSEg..aNRITRQVRTIIWLFRMLYDFAKQGQINHHKIIDELSYNTKNDKAFAVSGRITHRYMTCAELTKPRIEKKEIRKIILGGGQNLLSPERRFDAIIYNSPELF....
R7HRJ4_9BACT/1-140                  ...----------------------------...-----..----------------..-----------------------.------------....--------------------------------------------------------..--------------..-------------------------......----------MQPIWKTDKKMSDLDNNCLDVFVWSNLAVIQMALRENSSD---....DDISRNQRTIIWLYKMLWDFTQYGKFNYTDIVNSLSYKYKTDKAFAISGKLTSPFLRCAELEKPRISKYEIKNIILGDGQKLLRPERRFDAYLVSHPELF....
A0A077DF45_9BURK/22-350             ...WGKNQFNSSFPVALCCYMSHKNIEANYL...IVQNN..-KIIHTTIDIPSILNI..DPKDKNTFFAFETAHSPFTKYVV.GSLPRTDVVIQN....KNTGVCLRGLEIKLTALPDHTTCHLTDAEFGCEIVIRPDTICYLACSLAELFADNL..QQY-IILPKVSKKI..-NWSDPAQVITLFPDIKRTLENLCQ......VPESLQKPFLLQPIWKTEGKSSRLANNCLDVFVWSEIAFVQFILSISNLNTNI....FSINRQTRTAIWLYKMLVEIIQQGQFNHHRIIDECSYNTKNDKAFASSGQITNPFMQCKRLENPIISKSEIKEIILGGGQELLSPERRFDAIIYNSPELF....
A0A0M2Q267_PROHO/24-349             ...WGKNQFNTSFPASLCCYLNAKSIDANYL...SVQNG..-KLGFTSLPISDLFGI..DVESDDLYFAFEAQHTPYQKYVV.GSLPRTDLVIQR....ESTGECLRGLEIKLTALPDHTTCNCLDQDYGSELVVRPDTIIYLACSIAT---SQI..NNLRINIPNL--SI..SDWSDPREVLPHIKTIIESIYCLSD......FLSKQQTPFLIQPIWKTKGKSPSLADQCLDVFVWSDAGFSYFISQIANISPRA....NHITRQTRTAIWLFKMLLDISLNGKFNHQKIIDHLSYNTKNDKAFASAGTITNPYMACSRLTNPIIAKSEIQNIILGGGQNLLSPERRFDAIIYNSPELF....
A0A087ZTH5_APIME/24-347             ...WGKNQFNSSFPAALCNYLAYKNMNANFL...IMKNN..-QHKVSEISINEIYNS..SVIDTNLFFAFESQYTPYSSKVI.GSLPRIDLVL--....QKDGVCLRGLEIKLTALPDNTTYTFSDEHYGCELVVRPDTIVYLACSIAKHFYSK-..-IIKEIP---KINI..IDWSDPQEVLHSIDLIIFRLKKLVL......DFELKQTPFLLQPIWKTKGKKAELADYCLDVFVWSDIAFTSFITNISNSNIKA....KFITRQTRTAIWLYKMLEDILHNGRCCADTIIDKLAYNNKNDKAFASSGRITNPYMKCDCLTTPRIHKSEIKKIILGGGQNLLSPERRFDAIIVNSPNLF....
K9YGZ7_HALP7/27-362                 ...WGKNQFNTAFPTALGCYMHQKEIDPIYL...VLNSD..LEVEKKTIKVNSIYGI..NPLANETFYAFENQYNCYQHLVN.NGLPRIDLVINRi..qNKQLSPLRGIEIKLTALPDHTTFSESDENYGCEIVIRPDTIVYLALSIALKFQEEA..NALKDLISPHLEDIreNNWYDPDVMRQNSDKIISAIDAVLL......SRLSQQEPFLLQPIWKTEGKTLILHENCLDIFVWSDYALTRLFIDVCKSSSNR....QKITRHYRTAIWLAKMLVDFSKKGKIDQRGVIDNLTYDTKNDKAFAVSGKITRRYMKCDQITSPRIKRNEIKNIILNEGERMLSPERRFDAAILGTSEIF....
K9W1X6_9CYAN/27-361                 ...WGKNQFNNSFPTALACYMQSKELEPVYL...TLDQQ..LSINHTKINVSQLFGI..NPSSPHLFFAFESDYVPYRKTVI.GKLPRVDLVTQD...tSQSDSCLRGLEIKLTALPDSSTCNLTHEQYGCEIVTRPDTIVYLALSIANNFQQSQ..QELLNYLDPVCSKI..NDWSSAKSVLPVIPLLIQAIDRLLS......DNIEIQQPLVIQPIWKTQGKTFTLYENCLDIFVWSDFAFTRLFFDISKNFTKEn..lEVIQRPMRSVVWLAKMLYEFATNGKMNHKLIIDSLTYHTKNDKAFALSGNVTRLYMNCPELITPRVNKSEIKNIILGGGQNFLSPERRFDAVVLSNSEIF....
I3WFP7_BIFBI/46-384                 .mt--KNNFTTEAPISFLMYIDEVLKKPTVLiegTLNDKkqLSTHQAYVPLAEVFGA..DPC--NVGFRFEESFEGYDKYAT.NKANRSDVVVVD....RETGDHKSAFEVKLVVVPNSGTARKSHDDQSCEIVVRPPSIEQLTFSIADTYGKTGmeELRKIIVKFLGDSIqyFKWEDESFMLRRLPQIREAAEAIAK......AKLAQQKPFAITGLWRTQGQRGLLDENCFDSFVWTNLAFLQLFLVSAANRNDP...nAEITRPERSLIWLVRSLYDYACQGKVKFDWAHSAITYNQQTDKAGSFAGNIPFQFMNGPRLRKPAIPRDQLDDVIPMEALDLFMPERRLDATLFY-----gaqi
K9V6T6_9CYAN/28-362                 ...WGKNQFNSSFPASLACYMHSIQVQPVYL...KLNSS..LNIIQEQITVTELFGE..VPLSEKLFFAFESDYLPYRKIVI.GKLPRVDLVTQDi..kTNKDSCLKSLEIKLTALPDNSTYRLSDDRYGCEIVVRPDTIVYLALSIADKLQHNK..ETILEYLDPVFQTI..DNLTSIRSVLPKISEIVVSMDNLLL......NYLDIQSPLVMQPVWKTVGKTSKLFTNCLDMFIWSDFAFTRLFFDVAKKAAKN...aETITRSTRSVVWLAKMLYDFASNGKINHQFIIDNYTYNTKNDKAFAINGIGTYGYMKSPQLINPRIKKEEIKNIILGGGQNYLSPERRFDGIILSNPEIF....
K9RQK0_SYNP3/22-361                 ...WGKNCFNSSFPMALCCYMSHMNISPVYI...SIDNK..LNIKHEKESVSQLFGI..PSNSSDLFFGFETVYLPYQNFVH.GIYYSADVVLSN....KITRHQFRCFEIKLTALPDNTTCSLSDSEFSCEIVVRPSTIAFVALGIVNHISNTGlvQIFSRLLSPICSQI..QNWQDKNEILIHLSHFKQAMIDVISfllnqkQKIYTQQPLVIQPVWKTLGKSSTLHDNCLDTFIWSDLALILLPLHQINTSRRT....QNISRPARTIIWLIKMLYDFIINGQINIAQVIDTLTYDTKNDKAFAASGRVTHPFLSSPELTQPRIKKSEIKNIILNGGQNLLSPERRFDAIIVNTPGLF....
Q4CAI1_CROWT/75-205                 .lh----------------------------...-----..----------------..-----------------------.------------....--------------------------------------------------------..--------------..-------------------------......------------------------YDNCLDIFMWSNLAFTRLFIDAAKSELNS....DKITRHKMCVVWLAKMLYDFANTSKINHTATIDEISLNTKNDKAFALSGSKTHQYMKSPELTKPRIKQEEINNIILGGGEKLLSPERRFDAIILNTPNLF....
K9ZBE3_ANACC/26-359                 ...WGKNQFNNSFPASLACYMYQKGMKLNYL...VLDEN..LTIQHQEIDVSEIFGI..PPLSPNLFFSFESDYVPYRKIVI.GKLPRVDLVTHD...iNRDNACLRSIEIKLTALPDNSTYRLPDNQYGCEIVTRPDTIIYLALSIAHEFENSR..DKLLNYLQPVCSQI..EDWLSIRQVLPFVSQLVECLDNLLA......DYIEIQSPLVMQPIWKTVGKTSKLYQNCLDIFVWSNFGFTRLFFDITKRLAKS...eETIQRPMRSVVWLAKMLYEFALVGKINHKLIIDTLTYNTKNDKAFALSGSNTRRYMTCDNLIHPRITKEEIKNIILGGGQNFLSPERRFDAIILSNPEIF....
A0A075JTS7_9BACI/24-360             ...WGKNQFNSSFPAALACYMDSKNINPVYLklgSEDSS..LKVYKDYITVRNLFRIpeDKTIDDVYYEFEGLYEPHNELDR.-SLLRSDLVIKSltdgEEPPEYYSHHEVKLTAIPDSATYHKDEVQYGSEIVIRTVSIIHLAINIVEIYKHDK..LSLERLLNPVTDRI..TDWTDEYTLLELLPDMIYTLNSILS......ANLDKQSPLIMNPVWKTKGKTPALEDNCLDMFVWSDFALTRLFIDSINVN--R....TKIDRYSRALVWLLYLLHQSTFNDRIDSSKIY-TMPFHNQTDKAFASNGNKTNPYMRSNELLTPRIKREEIANIVLGGGQKMLSPERRFDAAISASTDIF....
T2D5_HAEIN/95-333                   tsh----------------------------...-----..----------------..-----------------------.------------....----------SIKLTALPDHTTCDLTDADFGSEIVIRPDSIVYLACSLAEILKESL..ANCMDIPNNVD--H..LDWSEPKQVIPLFPHILSTLNNLCS......RADTIQTPFLLQPVWKTLGKSPRLADNCLDIFIWSDVAFVKFILEISNLNVNV....LSINRQTRTAIWLYKMLVDIVKYGRFNHHKIIDLCSYNTKNDKAFASSGMITNVFMKSERLERPIIMKSEIKNIILGGGQELLSPERRFDAIIYNSSELF....
T2D5_HAEIN/35-99                    ...WGKNQFNSSFPVSLCCYMSSKGILANYL...SIENA..-EIKCSSIDIKDVFEI..EPENENTFFAFETSH--------.------------....--------------------------------------------------------..--------------..-------------------------......-----------------------------------------------------....----------------------------------------------------------------------------------------------------si..
A7BNK2_9GAMM/1-80                   ...----------------------------...-----..----------------..-----------------------.------------....--------------------------------------------------------..--------------..-------------------------......-----------------------------------------MFLEMATEPITQ....--INRPIRTLIWLFKMLYDFSQLGQIDYRYIIDALSFNTKNDKAFAVNGRITHPHMKSPFLTQPRIQQ--------------------------------ag..
A7C1H2_9GAMM/29-360                 ...WGKNQFNSSFPVALACYMSEKGFENIYL...QLDKN..LKIIHNRITSESLFGI..CPKSDDLFFAFETPYTPYQQLLI.GNMPRADVVIQN....SISGNCLRGLEIKLTALPDNVTCDLPENQYGCELVIRPDTIVYLACSIAMQYKNKRerKKLTTYIDNKFESI..SDWTEPKEVLPYVSEMVKVIEKITQ......DKILSQEPLIIQPVWKTLGKSPILAHDCLEVFVWSNLAFTRLFLDMATEPITQ....--INRSIRTIIWFFKMLYDFSVMGQIDYRCIIDKLSFNTKNDKAFATNGKITHSYMQSQFLTQPRILKSEIKNIILDGGQNLLSPERRFDAIIYNSPNLF....
D5EYH7_PRER2/36-367                 ...WGKNQFNSSFPASLVAYMGSKGVNPIYI...CTNKK..NEVVHKTINTTDLFGV..NPLGEDAYYNYEAEYYPYEQFYYaAKKEKIDLVMIN....RSTEVAASGLEVKLTTLPDNTTKDLEESEYGSEIVVRSPTILFLACSICSCYNSEKgkNRLHSILNTIGSEI..KNWSEIRQVLPHYKAICKAILDVSI......DLSNKQIPLIIQPIWKTDKKLKDFADDCLDVFVWSNLSVIQMCLRETNAD---....NDISRNQRTIIWLYKMLWDFSLYGSFNYTGIVNELAYNYKTDKAFSISGKLTNPLMRCPELTKPRISKYEIKNIILGDGQKLLSPERRFDAFIVSHPELF....
D4ZXW4_ARTPN/27-360                 ...WGKNCFNSSFPTALCCYLHDINLENIYI...KVNSN..LEIEHTKIATEDVFGI..NPQSDLAFYAFESPFTPYQQYLI.GTLPRVDLVT--....QTNGLCLRPMEIKLTALPDNTTCELPENEYGCEIVVRPDTIVYLACSIASTLRQQG..TNIAELLKLTFPQD..LDWTEPLSVIPYVSTMIEAIDNLMS......HIVLGQKPFLMQPIWKTQGKSPQLSTNCLDVFIWSDICFSRLFVNLAKQEIKTfgkiIKISRYTRTVIWLYKMLSDFADRGLFDYVSIIDSCSYNTKNDKAFAVNGKITHEYMKSEYLRKPRILKQEIKNIILGDGQNLLSPERRFDAIIYNSPDLF....
R7HTQ3_9BACT/35-149                 ...WGKNQFNSSFPASLVAYMSSKNMSPVFI...CTNKN..NEIVHKYISAIDLLGI..DPLSEDAYYDYEAGYYPYEQYYTaNRKEKIDLVMIN....RSTQSPMSGLEVKLTTLPDNTTKDLPDAEY--------------------------..--------------..-------------------------......-----------------------------------------------------....----------------------------------------------------------------------------------------------------....
R7JVX4_9CLOT/19-348                 ...WGKNCFNSSYPTATAAYMLHNNIPAIYIhlaDVNGQ..LQVVADEIPIKDVFNC.gSTQSEDLYFSFESIYEPYQQYSF.DTIDGIDLVVKD....L-SGNFLSPLEVKLTVLPTDSTCKQPEEKWGCELVIRSATTSYCALGMFDSVKNKS..QHIREIFENSCSSI..QMWDNDFEMTHKMATICQSINDFQS......QYYQHQKPLLMQTIWKTQGKSPLLAEQAFDIVIWSDYAFSRLFVDSSTSPANT....--MSRPMRATARLARCLWELSKSGKIRVADIYRQMAFGNQTDKEFAISGSKWRQYVKSDRILRPILSKTVVNDIIEPGYIQKLSPERRFDQTLY------ftv.
Q4CAI1_CROWT/27-78                  ...WGKNQFNSSFPAALACYMSCKNLQPVYL...KLNHD..LTVNHGKIDVSSLFGL..H----------------------.------------....--------------------------------------------------------..--------------..-------------------------......-----------------------------------------------------....----------------------------------------------------------------------------------------------------yd..
R6RHP0_9FIRM/19-349                 ...WGKNCFNSSFPTSLACYMLDNDIKAIYItlaVKDNK..LVIEPKEISISEVFNC.tNKSLRDLYFSFESIYEPYQQYSF.DAIDGIDLVVKD....I-NGNYLSPLEVKLTVIPTSQTSTLSEEKWGSEIVVRSATTSYCALGMFDSIKESA..QDVREIFEDACSSI..QMWDNDYEMTHKMPLLCQAVDDFQL......KYYSHQKPLLMQTLWKTQGQSPILADQAFDIVIWSDYAFSRLFLDHSAEPAET....--MRRGMRASARLARCLWELSKSGKIRVVDIYRQMAFGNQTDKEFAVGGSLWRKYVTPNRIQNLALKKDIVYQIIEPGYIDRLMPERRFDQTLY------ftmr
C0EI87_9FIRM/1-313                  ...-----------------MLDHNISAVYNkleEVNGR..LQVVPTEISIRDLFNC.gASSLNELYFSFETAFTPYQQYSF.DTVDGIDLVIKD....I-HDNFLAPLEVKLTVLPTAATSHLPEHKWGCELVVRSATTSYCALGMFDAVKEES..RAVREIFEESCASI..QSWDNDYEMTHKTPMLSECINQFQT......KYLTKQKPLLMQTIWKTQGQSPVLADDAFDIIVWSDYAFSRLFVDSAFKVERT....--MSRYMRASARLARCLWELSKSGKIRLADIYRQMAFGNQTDKEFAIQGPKWRKYVTTERIAQPILQKDVISEIIQPGYIEHLMPERRFDQTLY------ftv.
B1WX28_CYAA5/25-357                 ...WGKNQFNSSFPSALTCYMSYKNIQPVYL...TLDHK..LTVKHGKISVSSLFGL..DYSSPHLFFAFERDYIPYQDIVI.GNLPRIDLVTID...iSKNNLCLRGLEIKLTALPDNTTCELSDDKYGSEIVVRPPTIVYLSISIARAYQQDR..KILKDYLNPICNFI..TDWTSPSCILPIIDEIISVIDVVIS......SCLDSQIPLIMQPIWKTEGKSAQLHDNCLDIFMWSNLAFTRLFIDAAKLELNS....EKITRHKRCVVWLAKMLYDFANTSKINHTVTIDEISLNTKNDKAFALSGSRTHKYMKSPELTNPRIKREEINNIILGGGEKLLSPERRFDAIILNTPNLF....
R5ACP9_9FIRM/23-350                 ...WGKNQFNSSFPASLACYLHSKGMKAVYI...KAKPD..MKRDLQYIGIDELYGI..DPLGDDIFFSFETQYTPFQKYVI.GAIPRDDLVI--....LSDGQCVSSIEIKLVALPDNPTCNLSEDKFGSEIVVRPDTIIYLACSFIQSYEDNP..EALRNVIRDAGRNV..RDWTEAGEVLPYMDEIYWAIRRMVS......EKNECQSPIIMEPVWKTEGKSPRLADHCLDLFVWSNFGMLNLFMPEENEEFRT....--ITRHTRTMIWLFKMLQEYAEKGRFNGAKIIDTLSYNLKNDKAFASNGLRTHPIMTCAELTKPRITKGEIRKVILGGGQYLLSPERRFDAIIYNSPDLF....
#=GC seq_cons                       ...WGKNpFNoSFPsuLssYhtppshpshYl....hspp...pl.tppIslpplash..ss.spphaauFEs.a.PYpph.h.sth.phDlVh........st.hhpshElKLTsLPDssThphs-ppaGsElVlRssTI.alAhuhhp.htpp...p.hhphht.hh.pI...sWpp..phh.hhsthhtslppl........ph...QpPhlhQPlWKTpGKos.LtcsCLDlFlWSshAFspLFlc.uppt.pt......IsR.hRohlWLhKMLa-huppGphshptIlcphoassKsDKAFAhuGphTp.aMpsspLppPRIpKpEIppIILsGGpphLSPERRFDAhlhsssplF....
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