GenomeNet

Database: Pfam
Entry: RE_HpaII
LinkDB: RE_HpaII
Original site: RE_HpaII 
#=GF ID   RE_HpaII
#=GF AC   PF09561.8
#=GF DE   HpaII restriction endonuclease
#=GF AU   Coggill P
#=GF SE   Bateman A
#=GF GA   25.00 25.00;
#=GF TC   33.10 33.00;
#=GF NC   20.50 20.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   16723432
#=GF RT   DNA looping by two-site restriction endonucleases: heterogeneous
#=GF RT   probability distributions for loop size and unbinding force. 
#=GF RA   Gemmen GJ, Millin R, Smith DE; 
#=GF RL   Nucleic Acids Res. 2006;34:2864-2877.
#=GF RN   [2]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR019062;
#=GF CC   This family includes the HpaII (recognises and cleaves C^CGG)
#=GF CC   restriction endonuclease.
#=GF SQ   65
#=GS R6MXH0_9BACE/6-358      AC R6MXH0.1
#=GS B0VVC8_ACIBS/5-362      AC B0VVC8.1
#=GS I4Z845_9BACT/6-355      AC I4Z845.1
#=GS R6YJ11_9BACE/6-358      AC R6YJ11.1
#=GS B3JQJ7_9BACE/6-358      AC B3JQJ7.1
#=GS R5C7L1_9BACE/1-363      AC R5C7L1.1
#=GS A5Z803_9FIRM/5-355      AC A5Z803.1
#=GS R5IE26_9PORP/6-338      AC R5IE26.1
#=GS R7HTD5_9BACT/6-356      AC R7HTD5.1
#=GS F3PYR4_9BACE/6-371      AC F3PYR4.1
#=GS J5UCE0_9FIRM/1-186      AC J5UCE0.1
#=GS R7EB45_9BACE/6-371      AC R7EB45.1
#=GS H8XP00_FLAIG/5-357      AC H8XP00.1
#=GS D6D7C4_9BACE/6-358      AC D6D7C4.1
#=GS R6ULC0_9CLOT/7-361      AC R6ULC0.1
#=GS R5VD76_9BACE/6-358      AC R5VD76.1
#=GS R6D981_9BACE/6-358      AC R6D981.1
#=GS R5JIK7_9BACE/6-359      AC R5JIK7.1
#=GS R6FNR1_9BACE/6-369      AC R6FNR1.1
#=GS A0A0G0DUP5_9BACT/5-359  AC A0A0G0DUP5.1
#=GS R5W5Y4_9DELT/11-379     AC R5W5Y4.1
#=GS R5NWS1_9BACT/5-359      AC R5NWS1.1
#=GS K2ESG9_9BACT/1-249      AC K2ESG9.1
#=GS Q8A8L8_BACTN/6-358      AC Q8A8L8.1
#=GS K9YHI2_CYASC/304-651    AC K9YHI2.1
#=GS D4JS74_9FIRM/339-694    AC D4JS74.1
#=GS B1C827_9FIRM/8-374      AC B1C827.1
#=GS A0A0A2DWA8_9PORP/6-355  AC A0A0A2DWA8.1
#=GS J5UCZ2_9FIRM/2-82       AC J5UCZ2.1
#=GS R7DGX5_9PORP/1-284      AC R7DGX5.1
#=GS D1AWC1_STRM9/1-334      AC D1AWC1.1
#=GS F9VKB6_ARTSS/5-352      AC F9VKB6.1
#=GS R6MCC1_9BACE/22-388     AC R6MCC1.1
#=GS M9SEV7_9EURY/1-91       AC M9SEV7.1
#=GS S5ZY30_9SPIO/9-364      AC S5ZY30.1
#=GS A0A0G0HBE8_9BACT/5-208  AC A0A0G0HBE8.1
#=GS D4S662_9FIRM/13-362     AC D4S662.1
#=GS R7CYI9_9BACE/6-358      AC R7CYI9.1
#=GS A6H1V5_FLAPJ/5-356      AC A6H1V5.1
#=GS F0R0L7_BACSH/6-358      AC F0R0L7.1
#=GS R6RWP7_9BACE/6-358      AC R6RWP7.1
#=GS H6L4Y2_SAPGL/5-356      AC H6L4Y2.1
#=GS R5ULD7_9BACE/6-358      AC R5ULD7.1
#=GS F3ZUA3_9BACE/6-359      AC F3ZUA3.1
#=GS Q5LDN4_BACFN/6-359      AC Q5LDN4.1
#=GS A0A0G0H8K6_9BACT/1-157  AC A0A0G0H8K6.1
#=GS R5K7I8_9BACE/6-372      AC R5K7I8.1
#=GS R6SP07_9BACE/6-358      AC R6SP07.1
#=GS E8UDZ8_TAYEM/10-68      AC E8UDZ8.1
#=GS J5GMI7_9FIRM/5-360      AC J5GMI7.1
#=GS R6LHT0_9BACE/6-372      AC R6LHT0.1
#=GS E4TNH7_MARTH/5-363      AC E4TNH7.1
#=GS R5M6B8_9BACE/6-372      AC R5M6B8.1
#=GS E6SVX9_BACT6/6-371      AC E6SVX9.1
#=GS M4YJ48_9EURY/2-148      AC M4YJ48.1
#=GS R6A1Q5_9BACT/6-358      AC R6A1Q5.1
#=GS A0A075U4K6_9LACT/6-354  AC A0A075U4K6.1
#=GS R6CPC7_9BACE/6-358      AC R6CPC7.1
#=GS E8LGK0_9FIRM/1-130      AC E8LGK0.1
#=GS A6L7D1_BACV8/6-359      AC A6L7D1.1
#=GS W8VRS3_9FLAO/5-357      AC W8VRS3.1
#=GS Q30PG8_SULDN/306-657    AC Q30PG8.1
#=GS R7NP11_9BACE/6-359      AC R7NP11.1
#=GS A6ELS9_9BACT/5-357      AC A6ELS9.1
#=GS R7A9M9_9BACE/6-358      AC R7A9M9.1
R6MXH0_9BACE/6-358                 .........TKREWGELYAFFRLLADGYVYAGTPDVKRNEQQRIPVAM.VQREEHDGT.RQYIVEKD.-NIHIKGEKMDKL...........--VPREDFETVAELILQAI..RSS.KQ..DDVTSpDGVEEFLDEV.AIY.DLEAKT........DDRTDFSVAFYDVV-..--APLTGFCVRSRLGMMFPLLDGGR.TANFKFEQTGV.....KFAVPTINKINA...........EGE...E.DD....VISR.....MLMIERL.GGVLKYSDVADKIFRSNLAMIDLHMGRLLAEMTRLMWL..DGITKVSELTEEVKR..LNPLKIKdeLINKHGFYEYKIKEFLLALATGMRPAKLYNGTE.SAICGFLFVTGEGEVLCY.Q.RAYRQTFADFLFYNSRLEKGSTE..KDKYGYLERE.NGVYYFKLNLKIGL.......
B0VVC8_ACIBS/5-362                 .........NKGEWSEVYALFKLLSEGKLYAGDKDLNKIPNLIYPIIS.ILRQESQDL.LTYSPEPN.-HGVVHIQNGTST...........FTISQSDFKGITELLLTEI..KKKqPT..ASFSI.PEVETFISQY.NSK.KIKAKS........SAKSDIRIIIYDQKI..GTTPELGFSIKSKLGKASTLLNASQ.ATNFVYKVKNL.....TLSPQEIDDFNQ...........LEF...T.VP...iIQGR.....IHHLESL.GGSVEFSHITNDVFNNNLILLDSLLPNIISEALYKYYT..SPITSVKEIFEQVAS..ANPIHYS..LQHQHPFYEYKVKKLLCEIAIGMMPSTVWTGNNiDATGGYLVIKEDGDVICY.H.LYHRHEFEEYLYNNTRFEAASKS..RHNYGNLFIE.NGELYMTLNLQIRF.......
I4Z845_9BACT/6-355                 .........NKGEWSELYAFLKLLGEGKLYCGDGALNRYDDKCYPILK.IFRNDDEDR.NSYIIKTS.SKEISIQGEHINT...........-TLSQQRFKEEAQTLLAHI..KG-.ME..ATANF.PYLYEFLQEI.DIQ.HIKAKS........KDKADIRIVIHNLNT..GSKPELGYSIKSKLGAPSTLINANKnGTNFIYEIQNI.....--SEADVATFNN...........LDN...-.--....FKKK.....FEFLDTT.SAKIVFHKVANHTLHNNLMLLDLGMERIIAETLLAYYT..KKGKEVDEITQIISQ..TDPLEIA..KNTDQPMYEYKMKQWLLAFALGMTCTTPWYGNF.NANGGYIIVKEDGDIVCY.H.FFDRNDLENYLFHNTKFESPSTS..RHLFGNIYQE.GKLYFMKLNLQVRF.......
R6YJ11_9BACE/6-358                 .........TKREWGELYAFFRLLADGYVQAGTPDAKADETVRFPVAM.IQREEHDGT.RRYTIEKE.-MIHIQGEDMDKR...........--VPREDFETVADLILEGI..RQA.DT..DEVTSpDGVEEFLDEV.AIF.NLEAQT........DDRTDFSVAFYQPD-..--APLTGFCVRSRFGKMFPLMDGGR.AANFKFEQTGVk..faVPTVNKINA---...........EGA...E.DD....VISR.....MLMIERL.GGVLKYNDVADKIFRSNLSMIDLHMGRLLGEMTRLMWL..DGITKVSELTEEIKK..LNPLKIKdeLISKHGFYEYKIKEFLLALAGGMRPAKLYNGKD.SAIAGFLFVTADGQVLCY.Q.RAYRQTFAEFLFQNTRLEKGSTE..KDKYGFLERE.NGVYYLKLNLKIGL.......
B3JQJ7_9BACE/6-358                 .........TKREWGELYAFFRLLANGYVYAGTSDVKKNEQQCIPIAM.VQREEHDGT.RQYVIEKN.-NIHIKGEKIDKL...........--VPREDFETVAELILHAI..RNS.RQ..DDVTSpDGVEEFLDEV.AIY.DLEAKT........DDRTDFSVAFYDES-..--APLTGFCVRSRLGMMLPLLDGGR.TANFKFEQTGV.....KFAVPTINKINA...........EGE...E.DD....VISR.....MLMIERL.GGVLKYNDVADKIFRSNLSMIDLHMGRLLAEMTRLMWL..DGITKVSELTEAIKQ..LNPLKIKdeLINKHGFYEYKIKEFLLALATGMRPAKLYNGIE.SAICGFLFVTGDGDVLCY.Q.RAYRQVFADSLFYNSRLEKGSTE..KDKYGYLERE.NGVYYFKLNLKIGL.......
R5C7L1_9BACE/1-363                 ........m-----GEIYAFFRLLADGSVYMGTPQVQKDMNRCWPVAL.VQREEHDGT.RRYYIEED.-EIRMVSGEVDRSgqfvpkeeaesVTFPRADFGEAADYVLDIL..KHS.SG..EEVEVpDGLEGFLDAV.RIY.DLEAKT........DDRTDFKIAFWQKD-..--APLTGFCVRCRLSPMNPLLDGGR.TANLKLEQTGVk..faVPTVNKVNALP-...........-ES...P.NE....VAER.....MLMIERL.GGVLKYSDVADRVFRCNLLMIDLHFPRMLAEMVRLMHL..EGITRVSELTERIKE..LNPLKIKdeLIQKHGFYEYKMKQFLLALALGMRPAKIFRGTD.SAVEGMLLVDGQGEVLCY.H.QSCRQDFAEFLYQNTRFEKGALE..KDKYGFLERE.NGSWYFKLNVKIGL.......
A5Z803_9FIRM/5-355                 .........NKGEWSELYVLLRLLAYGRIYAADDQVKKIENVYFPILK.IMREEVKGKkLEYRIGTN.EDIEIYNNDIKIK...........-SVSREQLKKEADYLYNEI..VNM.KS..RSFEI.EHTEKFANAI.ECY.RLAAPS........SDKTDITMQIHDIHT..GFEPICGFSIKSELGSAPTLLNASG.ATNFAFEVEGI.....--NDEQMEQINA...........LNN...PkSK....IMDR.....MEQIFSL.G-IVKYSKPLNEKFANNLMLIDSRMEEIIAQVLICYYR..DNISDCKDIINKLEE..ENPLRFP..---NKGFYEFKFKKFLCSVALGMMPSKEWDGHD.EANGGYIIVSSDGDVLAY.H.IYNRDYFEKYLLDNTKLERGSTS..RHGFASLYKE.DGKIYMNLNLQVRF.......
R5IE26_9PORP/6-338                 .........TKQDWSKIYALIQLLLKGTIENTD------------IQK.IIRKDESGE.IVYHISSD.---IIHIKQGEEY...........VQISRQACKDFSSFLFSAI..QKS.NE..KEFII.PEAETMLHTL.RYN.QFYSIS........SDKRDFTISLSD---..--STHIPIMVKSRI-PYYKLLPANR.AANIKYDILNIk..fsNPEANKINRIDN...........LDT...-.--....---R.....LYEIKRL.GGKLKYTTTENKIFLYNLSIIDLHLPKLLSEITRLFYI..TKTCSIKKLIEEIKH..INPYKIKeeLISQYQFYEYKTIQFLLSLIDGMKPSKIYKGYG.NSLS-QLFVQPDGSIALF.H.NSDKKYLGSFLLDNAYLSIPDCE..SYRFGFIEKE.NNQWYIKLNLEI--fi.....
R7HTD5_9BACT/6-356                 .........NRGEWSELYALLKLLADGRLYCGDASQNRQDDRFFPILK.IFRNDQIDR.TAYTVNAA.KKEILVSRTNDCT...........IDVSQEEMQTKAHSILNVI..KT-.HT..GTFDI.PEIHNFLERI.DCK.TIKAKS........TDKADIRIVIHDLNT..GSKPELGYSIKSKLGGNSTLINANKdSTNFIYQVINV.....--DHSQMSEFNK...........LG-...-.-K....FGAK.....FNYLEEI.GAKLSFIGTARKETHNNLTLLDLGLERILADELLLYYS..TNLSSLEEITRQETN..DDPLILT..QNTTQPMYEYKIKQFLLAFALGMTCSKPWHGTF.NANGGYIVIKEDGDIICY.H.FFDRNDLENYLFYNTKFDTPSTS..RHLFGKIYEQ.GGHFFIKLNLQVRF.......
F3PYR4_9BACE/6-371                 .........TKRELGELYTFFRLLADGAVSLGTPKAEKDGKQSWPVAL.IQREEHDGT.RRYYIEEE.-DVRIVSGAIGKDgtfip.gskeeHCFPREDFGDASEMILHLL..KTV.SG..EEVEVsEGLEAFLDAV.NIY.DLESRT........EDRTDFSVAFWHPE-..--APLTGFNVRCRLAPMNPLLDGGR.TANLKLEQSGVk..faVPTVNKVNALP-...........-ES...P.TE....VAER.....MMMIERL.GGVLKYADVADRVFRCNLLMIDLHFPRMLVEMVRLMHL..DGITRISELTERIKE..MNPLKIKdeLINKHGFYEFKMKQFLLVLALGMRPAKIYNGTD.SAVEGMFLTNGDGQVLCY.H.KSRPQVFADFLYQNTRLEKGAID..KDKYGFLERE.NGVWYFKLNVKIGL.......
J5UCE0_9FIRM/1-186                 .......mv---------------------------------------.---------.--------.-------------...........-------------------..---.--..-----.----------.---.------........---------------..-------------------------.-----------.....-REANEIYIVSA...........GKT...H.TD....VRGR.....INKIIDE.NGQLKYYKMNNQTFSDNLVLIYSNMDRIIAETLLYFYK..DGISNCDEMIEKLER..ENPMNYG..NVNA---YKYKFKKFLTAVALGMKPATVWDGVD.EATGGYIVVTKEGNVLAY.H.IYNRNYFEEYLLKNTKYETASTS..RHDFGEVYSE.NGEDFIKLNLQVRF.......
R7EB45_9BACE/6-371                 .........TKRELGELYTFFRLLADGAVSPGTPKAEKDETLRWPVAL.IQREEHDGT.RRYYIEEQ.-EVRIVSGTTGKDgsfvp.gekeeLRFPREDFGDAAELVLHLL..KNV.SG..EEVEVtEGLEAFLDAV.NIF.DLEAKT........EDRTDFSVAFWHPE-..--APLTGFNVRCRLTPMNPLLDGGR.TANLKLEQSGVk..faVPTVNKVNALP-...........-ES...P.TE....VAER.....MMMIERL.GGVLKYADVADRVFRCNLLMIDLHFPRMLAEMVRLMHL..DGITRISELTERIKE..MNPLKIKdeLINKHRFYEFKMKQFLLALALGMRPAKIYNGTD.SAVEGIFLTDGSGQVLCY.H.KSRPQVFADFLYQNTRLEKGAVE..KDKYGFLERE.NGVWYFKLNVKIGL.......
H8XP00_FLAIG/5-357                 .........NKGEWSEVYTLLKVISDKQLFAGDSNLNKIETLIFPIIK.VLRDETNGT.FEFSYDND.---LVIVKNGEEE...........IRISVLEFQKQAHFLLTKL..KEK.TN..ATFSI.PEIESFINSF.DSH.SLKAKS........SVKSDIRIVIHDLRT..GTNPELGFSIKSQLGGASTLLNAGK.TTNFIFKIQNL.....TLTQNQISEINA...........IET...R.SK....IKDR.....IEKISEF.GGSLEFQKTESSIFGNNLILIDSALPKIIAESLKLFYT..STFSTTIELTNQIST..TNPLDYN..LETNHPFYSYKIKRFLTDIALGMMPSKVWTGEL.DATGGYLVVKENGEVLCY.H.IYNRNEFEDYLYSNTKLETASST..RHEFGKVYEE.NGQLYFKLNLQIRF.......
D6D7C4_9BACE/6-358                 .........TKKEWCELYSFFRLLTDGKVVLGTADAKAGET-SWPIAM.IQREEHDGT.RQYYIEED.-TIRIEAESGTKF...........--MPREDFGIVADLILRAV..KSS.SE..EDVTSpEGVEEFLDEA.AIF.DLEAKT........EDRTDFSIAFWHPE-..--APFRGFNVRSRLGVMNPLLDGGR.AANLKLEQSGVk..faTPTVNKINALP-...........-ES...P.NE....VAER.....MMMIERL.GGVLKYSDVADRVFRSNLLMIDLHFPRVLTEMVRIMHL..DGISRISELTEVIKQ..MNPLKIKdeLINKHKFYEFKMKQFLLALALGMRPAKIYNGLD.SAVEGILLVGGSGEVLCY.H.KSEKQVMEDFLFQNTRLEKGSLE..KDKYGFLERE.NGVYYFKLNAKIGL.......
R6ULC0_9CLOT/7-361                 .........NKGEWSEIYAFLRLLEIKKLYAADAELNKKDDMFYNIIS.IIRTEPIGT.LEFRINKA.DDTVSVIKTDTEDv.........lLTLPRDEFKTAADNLYNEI..INA.NK..SSFES.QDTEEFLEQL.NIG.VLKAKS........TDKADIRIKIHDINT..GYETVQGFSIKSRLGSPSTLVNAGK.TTNFVFEVIG-.....---NINDDVMNG...........FNT...C.SK...kFKDR.....FDFLSGY.DCDIEYCSMDNDIFESNLQLIDGDLPKICAYMLKEYYS..SGVNTVTNSLESLNV..NNPIGYN..LSKGHPFYEYKFKKFLAECALGMLPSKVWDGTA.DATGGYIIVREDGEVLCY.H.LFNRNEFETYLINNTKFETASTS..RHEFGSIYKE.NGKFYIKLNLQVRF.......
R5VD76_9BACE/6-358                 .........TKREWGELYAFFRLLADGYVYGGTPDVKKNEALRLPVAM.VQREEHDGT.RQYILEKD.-TVHLKGENIDKR...........--IPREDFATVAELIYAAI..RQS.RE..DDVTSpDGVEEFLDEV.AIF.DLEAKT........DDRTDFSVAFYSVD-..--APLTGFCVRSRLGMMIPLLDGGR.TANFKFEQTGVk..faTPTVNKINAE--...........-GE...E.DD....VISR.....MLMIERL.GGTLKYSDVADKIFRSNLSMIDLHMGRLMAEMTRLMWL..DGITKVSELTEEIKK..LNPLKIKdeLITKHGFYEYKVKELLLALAMGLRPAKLYNGTD.SAIAGFLFVTGDGEVLCY.Q.RAFRQTFADFLFQNSRLEKGSTE..KDKYGYLERE.NGVYYFKLNLKIGL.......
R6D981_9BACE/6-358                 .........TKKEWCELYTFFRLLVDGKVVLGTAEAKAGE-ISWPVAM.IQREEHDGT.RRYYIEEE.-TIRIEGETGIKS...........--MPREDFGIVAELILQAV..KSS.SE..NDVTSpDGVEEFLDEA.GIF.DLEAKT........EDRTDFSVAFWHPE-..--APLRGFNVRSRLSAMNPLLDGGR.AANLKLEQSGIk..faTPTVNKINALP-...........-ES...P.NE....VAER.....MMMIERL.GGVLKYSDVADRVFRSNLLMIDLHFPRVLTEMVRIMHL..DGVSRISELTEIIKQ..INPLKIKdeLINKHKFYEFKMKQFLMALALGMRPAKIYNGQD.SAVEGILLVDGNGNVLCY.H.KSEKQVMEDFLFLNTRLEKGSLD..KDKYGFLERE.NGVYYFKLNAKIGL.......
R5JIK7_9BACE/6-359                 .........TKREWSELYAFFHLLADGQVALGTPQVKADEERCWPIAM.IQREEHDGT.RRYYIEKE.-DIHIVGENIDKR...........--IAREDFDIVSGLILTAM..KSS.SE..DDVTSpDGVEEFLDEV.AIL.DLEAKT........DDRTDFSVAFWHPE-..--APLTGLNVRSRLSAMNPLLDGGR.SANLKLEQTGVk..faVPTVNKINALP-...........-ES...P.TE....VAER.....MMMIERL.GGILKYSDVADRVFRCNLSMIDLHFPRVLAEMVRIMHL..DGITRISELTEEIKA..INPLKIKdeLINKHGFYEFKMKQFLLALALGMRPAKIYNGTD.SAVEGILLVDGSGQVLCY.H.KSEKKVFEDFLYLNTRLEKGSLD..KDKYGFLERE.NGVYYFKLNVKIGL.......
R6FNR1_9BACE/6-369                 .........TKRELGEIYTFFRLLADGVVAMGTPQAVADEGERWPVAM.IQREEHDGT.RRYYVGED.--IRTVSGSLEKNgnflp.rpdseRHFPREDFATAATLVLDLL..KL-.PG..EEVEVdDSLEAFLDAV.CIY.DLEART........DDRTDFSIAFWHAD-..--APLMGFAVRCRLSPMNPLLDGGR.TANLKFEQTGIk..faVPTVNKINALP-...........-EA...P.NE....VADR.....MLMIERL.GGVLKYADVADRVFRCNLLMIDLHFPRMLAEMVRLMHL..EGITRVSELTERIRE..INPLKIKdeLIQKHHFYEYKMKQFLMALALGMRPAKIYNGTD.SAVEGMLLTDGKGEVICY.H.RSRYQVFADFLFQNTRFEKGSLD..KDKYGFLERE.NGSYYFKLNAKIGL.......
A0A0G0DUP5_9BACT/5-359             .........NKGEWSEFYAFLKILTDGKMFTADKDLEILRDNFYIVLK.IIREETNGK.KSYDISKG.DGKIVIKDDVVSGl.........nDVVEIEKIKNRVVDIFEKM..KNS.RN..TTFEI.SLAEKTMKDL.HCS.QIKASS........GRKADLMIVLHDKKS..PAFPELGFSIKSMLGSPSTLLNASG.ATNFIYSVIDY.....-SDVNEDSAS--...........CNG...A.LT....VRDK.....ASHIYGS.GGCLKYCGMDSEGFRKNLRKIDSKFPEIIAEIIKSYYN..GKGSKISDLVNYISE..DTEFCAK..LDFNKSDFVFKVKRFLSDVALGMTPKKEWDGYA.KAHGGYIIVKENGEIVCY.H.IYNRDEFEEYLYNNTKLDTPSTT..RHKFGYVYKE.NEEKKIKYNLQIRF.......
R5W5Y4_9DELT/11-379                .........NKGEWAEFYVMLKLLGEGKLYAADNKLKKKLDSYLDVLK.IIRQEYETQvLEYIVDRD.DSSVIVKPQGAETv.........lATIPMTEFEKCATTLFQGI..KHA.KG..MSVAApDSVCEFAKVI.YVG.KPKAPAvkalkrqfGGKNDIFIEVRDGQT..AIVSVMGFSIKSKFGHNPTLFNAGS.SSQYLFRLSGC.....-----DDTIMKK...........FNG...I.TD...gKGGRawgccVQYLRSH.RIGTEFARTQYPIYGENLYLVRESMARIMAWCVHDRLLagEPEHRVKETVERMAA..ANPLGVG..--NPDIYYEKAIKDFLIAGFTGMTAGSKWDGKE.QVNGGYIVVMDDGDVICY.H.SNDRESFRDYLYRNTYFEYVSAD..KYNWGYIVKI.DGEYYLPLNISVRF.......
R5NWS1_9BACT/5-359                 .........TRREWNELYVFFNLLAQGGIVLGNEEGLPSGR-VLPIFQ.VTRQEHDGE.RRYTVEET.-DIHVEGEQMDER...........--FPREDFGTVAAMILDTL..KRE.RN..EEVEApEGVEGFLDAL.KIY.DMEART........DDRTDFYITFHDSS-..--FPPVGFRIYSRLCAMMPLLDGGR.TANLKFEQGGIr..fsQPAVNKINYTDD...........PDN...P.NE....VARR.....MLYIESM.GGVLKYNDVADKVFRSNLCMIDLNLPRVLAEMVRLMHL..DNISRVDELTELIEE..RNPLKIKeeLIRKHRYYRYKMKEFLLALALGMRPAKQYNGTD.SAVAGFVMVDAEGRMVAY.R.KTERQVFADFLFKHTRLEKGHPE..KDKYGYLERE.NRAYYLKLNLKISF.......
K2ESG9_9BACT/1-249                 ........m---------------------------------------.---------.--------.-------------...........-------------------..---.--..-----.-------SDL.KCT.QIKAGN........ADKADLTAKIKEQGS..PMIIDLGFSIKSMLGGAATLLNASG.ATNFVYKIENF.....---NGNIEEVNA...........IEG...R.SK....VRDR.....IKAIEDA.GGRISFDSLAKIIFKNNLRMIDIALPEIMAKALLNFYK..GNGSIISDACASLPN..DAELKEK..YDLSQRDFEYKIKAFLRAVALGMVPNKEWNGLS.AAHGGYLIVKENGDVVCY.H.LHNMDAFQEYLFRNTKFDTASTR..RHGFGKIYEK.DGNLFINLNLQIRF.......
Q8A8L8_BACTN/6-358                 .........TKREWCELYTFFRLLTEGKVTLGTAKAKKGE-IDWPIAM.IQREEHDGT.RCYYIEKE.-MVRIKGENSEKF...........--VPREDFGIVADLILQAV..KSS.SE..DEVTSpDGVEEFLDEV.AIF.DLEAKT........EDRTDFYIAFWHPE-..--APLSGFSVRSRLGAMNPLLDGGR.AANLKLEQSGVk..faTPTVNKINALP-...........-EA...P.NE....VAER.....MLLIERL.GGVLKYSDVADRVFRSNLLMIDLHFPRVLTEMVRIMHL..DDITRISELTEVIKQ..MNPLKIKdeLVNKHGFYEFKVKQFLMALALGMRPAKIYTGQD.SAVEGILLMDGSGEVLCY.H.KSEKPVMEDFLFLNTRLEKGSLD..KDKYGFLERE.NGTYYFKLNAKIGL.......
K9YHI2_CYASC/304-651               .........NKGEWTERYSFFKIINDQRINLADKTLQKNNS-YFNVTK.ISTLNLD--.ENIILVDK.DSIIVENKITKSKk.........eINISELINQNVLDNLVNQI..KD-.NK..GTFEI.NEMIAIQNKL.GIS.IIKGGQ.......sNQKSDVILDI-NKDH..FFKVNEGFGIKSYLGNKPTLLNASG.NTNFIFRVNNL.....--SSYSLDEINN...........IK-...-.-K....LKDR.....INKIINL.GGIFSFYKIEKETMAYNLRIIDSMMPNLLAEMLLEFFV..HRNNLISENLLTIYQ..-KQLAQT..MIDDLPSLTIKLKRFLVGVLLGFFAETKWDGKY.-SSNGTIVVKENGEQLAF.H.IIDIVSLEDYLFENIVFDTPSTT..RHRYGKLILEnDGCLYFKLNLQLRF.......
D4JS74_9FIRM/339-694               .........NKGEWSEIYVFLRLLAIGKLYAADAELNKLSDVFYNILN.ILRSENTGN.MEFRVERA.ANRISVYNTDTESi.........iADLPANEFKLAADELYNEI..AAA.NK..ASFEV.RNIESFLETI.KIE.TLKAKS........TDKADIRIKIHDINT..GYESVQGFSIKSRLGGASTLINAGK.TTNFIFEVTG-.....---NVDDEVMDE...........FNN...C.SK...lFKNK.....FTYLRGTaGCDIKYFGMENETFEDNLSLIDGDLPEICAYMLAEYYS..SGVNTVSKSLEAIAG..RNPMNYR..LDKGQPFYQYKFKKFLTDSALGMLPSKPWDGTA.DATGGYIIVREDGEVLCY.H.LFNRNEFENYLINNTKFETASTG..RHEFGSIYKD.CGKYYLKLNLQIRF.......
B1C827_9FIRM/8-374                 .........NKGEWSEVYTFLYLLSKGRLYGADSELNRLEDVFYDIIK.IIRHEKKGV.LNFIVSENeKDIEIVDGNDNHL...........ITLQMSEFDKKANLLLNKI.iNQK.TA..GAFEV.PEITDFLNKI.NCF.KLKAPS........KDKSDITLKVHDFHT..GIDPTLGFSIKSRLGKPSTLLNAGK.NTNFIYKLNGNftdddM---NKVNSMVH...........IKKtkkG.EKvetaIGER.....LSYILSK.DIKLTHFDISGKNFKNNLILIDTMLPNIISNMLLEYYS..TGVSNIKILLDKIIE..ENPLNFD..LSENHPFYSYKFKKFITESALGMLPGTVWTGKA.NATGGYIVVKEDGDVLCY.H.LYNRNEFEDYLLNNTRFERASAS..RHDFAKVYKI.NNDYFINLNLQIRF.......
A0A0A2DWA8_9PORP/6-355             .........NKGEWSELYAFFKLLADGCLYCGDGELNRYDDKFYPILK.IFRDDNKNR.NTYEVKKE.-KILISGQ--NIY...........IEVSQEEFKAEAGKLLKLI..KN-.LN..KESDF.SDTEKFMNRM.DIH.SIKAKS........SDKADIRIVIHNLVT..GSKPELGYSIKSKLGGDPTLINANKnGTNFIFKVTGI.....KFSGQQIEKCNS...........YK-...-.-Y....FKQK.....FKYLESI.GASIEYYKVAGDILHNNLLLLDLGLEKIIAEALYLYYS..GKGSNIKEITDCISK..KDPLGIM..NDVRQPMYAYKVKQFLLAFALGMTSTTPWYGKF.HANGGYIIVKQDGDVVCY.H.FFDRNDLEDYLFYNTYFDTPSKN..RHEFGKIYCE.NGEYFIKLNLQIRF.......
J5UCZ2_9FIRM/2-82                  .....hyph-------------------VYKTENFLESDAIVYFPIIK.IIREENKGE.IKEYAAGE.IISIYINGSKVKE...........--LPATEFETQSKLLLNEI..NSKtSK..-----.----------.---.------........---------------..-------------------------.-----------.....------------...........---...-.--....----.....-------.--------------------------------------..---------------..-------..---------------------------------.------------------.-.-----------------------..----------.--------------gdfl...
R7DGX5_9PORP/1-284                 ........m---------------------------------------.---------.--------.-------------...........---PRIKCKNAATEILSTL..QET.KE..NDYSV.PSCDPILETL.HYT.WFQSTA........DDKSDFSVIYFDPEKeiAQRQEITVCIKSKW----NILPANR.ANNLKYDIQNV.....KFSNPESNRINR...........IDG...A.QE....VQQR.....LTEIYRL.GGKLKYTTAENKFFLENLCMIDLHFPKLLAEITRLFYT..TGLSAIPEIITEIKN..TNPYKIKeeLIYKNNFYEYKVQQLLYALATGLRSTKRYRGYG.HTRT-FAIIDTCGEIELL.D.STKRTEFDRYLYQNAKLSMGNSK..THKFGFVEKE.NGQWFIKLNIEI--ii.....
D1AWC1_STRM9/1-334                 .......mv----------------NKQLKLVNCKLEIVNDSIFTVKS.IISENKKGN.IIFEIKDN.KVYPIIYDNKLEA...........--IDIDDIKQFYELMYNEI..YNS.NNgiGSFNI.TSINSLLFKL.GIEnNFKSIA........NKKDDITLINLDNNK..NINVKLSYSIKSQLGRPAIILNASK.HTNFIYKITNI.....--SEDDVKRINS...........INT...P.SK....LKDR.....IHELEKI.NANIEFVGLTSDAFEKNLKMIDYKLPDVLAEVLLNSYK..NDEKFLKKLFSESSIyeTNELSI-..---------KKLKDFLEAISFGIMPSKEWNGIN.NVNGGIIIVSNDKKIYVL.DmIYFSDEVRKYLLENTKLDSPSST..RYNMLNIYKK.NNEFYFTLNLQVRY.......
F9VKB6_ARTSS/5-352                 .........NKGEWNEFYALLYLLENNNISIVDSDLCVIDSAIFFINKlVTQGETS--.LTYQKVDD.EIIIFKNTQKIGV...........--VSLDAVIKAKEFLLKTLinKKPlNG..GSIKL.PSLNEFIENFtDGY.SIKGKA........KSKADLGANVKDNKI..CKDVNITYSLKSQFGSPATLLNASK.HTNFMHKVQGF.....--DKDKMQEVNR...........IKT...K.KK....LLDR.....IYKIKEL.EGKIEFYKIVSNTLERNIRLIDSSMDKLLANALLYSYV..ENEKDLQKAFLKSNH..-------..-GNDEVFLRKKLIDFLYGICFGFFPSEEWDGKY.SVNGGIMVTKNSGEVVLLdK.IYHNEILENYLYYKSKFDSPSTS..RYHMLEIFED.SGDFFFTLNLQIR-s......
R6MCC1_9BACE/22-388                .........TKRELGELYTFFRLLADGKVFPGTPNAQREDKKCWPVAL.IQREEHDGT.RRYYIGEE.-DVRIVSGTVEKDgtftassekeeLSFPRADFGDAAEIILHLL..RNE.QG..EEVEVsEGLEAFLDAV.NIY.DLESKT........DDRTDFSVAFWSAD-..--APLTGFTVRCRLGRMNPLLDGGR.TANLKLEQSGVk..faVPTVNKVNALP-...........-ES...P.AE....VAER.....MLMIERL.GGVLKYSDVADRVFRCNLLMIDLHFPRMLAEMVRIMHL..DGITRVAELTERIKE..MNPLKIKdeLINKHCFYEFKMKQFLLALALGMRPAKIYNGTD.SAVEGLLLTNGDGEVLCY.H.KSDRQMFADFLYRNTRFEKGSVD..KDKYGFLERE.NGVYYFKLNVKIGL.......
M9SEV7_9EURY/1-91                  .........---------------------------------------.---------.--------.-------------...........-------------------..---.--..-----.----------.---.------........---------------..-------------------------.-----------.....------------...........---...-.--....----.....MRYMRKR.GLGFRFLRMEDRAFEDTLRSYDPDMPEILAWMVSEAYL..NGTCRASDILDNIES..VNPLGYD..RPRANGTYRKKVVGLLSRY--------------.------------------.-.-----------------------..----------.--------------segae..
S5ZY30_9SPIO/9-364                 .........NKGEWSEIYVLLRLLADGKIYAADSELNKLKDVYFPIIK.IIREENKGE.IKEYSTGE.IVAIYINGSKVKE...........--LPATEFEMQSELLLNEI..NSKiSK..GAFSV.EKTQNFMDKI.LCY.KLSAPA........TDKSDITIKIIDINT..GYSPTVGFSIKSELGSSPTLLNAGK.TTNFIYKIIHGyp.dlVREANEIYIVSA...........GKN...H.TD....VRGR.....INKIIDE.NGQLKYWKMNNQTFRDNLVLIDSNMDKIIAETLLYFYR..DGISNCDEMVEKLER..ENPMNYG..NVNA---YRYKFKKFLTAVALGMKPATVWDGVD.EATGGYIVVTKEGYVLAY.H.IYNRNYFEEYLLKNTKYETASTS..RHDFGEIYSE.NGKDFINLNLQVRF.......
A0A0G0HBE8_9BACT/5-208             .........NKGEWSEFYVLIKLIADKRLVGADDDLKKIESIFFPILK.IVREDSTGK.YEYELLAG.EKIKLLCPNGQKF...........-IVNVSDLKSKVAQIFGFV..KK-.SH..KTFSV.PAAKELFRRF.RIK.SLNAGN........SRKEDLVLKIHDHTI..NRNHEVGFSIKSKLGSPATLLNAST.ATNFTFKINRL.....--NDNQVEKINR...........IST...K.AK....IRDR.....LSAIGAA.GGVIEFKKVD----------------------------..---------------..-------..---------------------------------.------------------.-.-----------------------..----------.--------------s......
D4S662_9FIRM/13-362                .........NQGEWSELYVLVHLLGTGRLYAADAELNALADCFFPILK.VMRSEDEDRqIDMTVRDH.-GVEITCNGMAVH...........-TVKRSLLTSYAKALLDAI..RV-.GR..GAFAI.PLAAEVMEHL.SIC.KVKASS........AEKADITMLLHDIHT..GIENVFAFSIKSYIGAAPTLLNASK.STNFVFAVEGL.....--DGADISRINA...........IEG...R.KK....LLER.....MQEISAA.GGSLRYIRPASDMFRNNLSFIDMSFDRLLAALLLESYH..SGELNCRKLLQTVAE..ANPFHVA..--DPQKLYEYKFKKFLCAVALGMQPAKAWSGTE.DASGGYIIARADGAVVAY.H.IYNRNFFEEYLLCSTRLERASSS..RNDYCCIYEV.DGIHYINLNLQIRF.......
R7CYI9_9BACE/6-358                 .........TKREWGEVQSFLRLLADGYVCAGTPTGEACTERPYRIAV.VQREEHDGT.RRYLIEGD.-DIHIVGEKMDKR...........--VPREYFKAAAELIADAM..KRT.HT..DGMESpDGVEEFLDEI.AVY.DLEAKT........DDRTDYHIGFWTVE-..--APLVGFRVCSRLAPMNPLLDGGR.TANLKFEQTGV.....KFATPTVNKINA...........LES...P.NE....VIDR.....MRMIDRL.GGVLKYSDVADKVFRSNLSMIDLHFPRLLAEMVRTMYV..EDMTRVSELTERIRE..INPLKIKeeLITKHRFYEYKMKQFLLALALGMRPAKLFNGTD.SAVEGFIMVDTEGCPVCY.Q.KADKGTFEDFLFRNTRFEKGSLE..KDKYGYLERE.NGAYFFKLNAKIGF.......
A6H1V5_FLAPJ/5-356                 .........NKGEWSEVYALFKLLGDKQLFAGDANLNKVEELFYPIIK.IIRNESGGN.FQYEINGD.---LVIISGGKEE...........LRIPVKTFTEQSAKLLSTI..KG-.ST..GAFNI.PEIETFMNSI.NCS.SLKAKS........TSKSDIRIVIHDQRI..SQTAELGFSIKSQLGGQATLLNAGK.TTNFVYQVSGF.....QPIENEIQTINE...........IDT...K.SK....IKDR.....IESVKQF.GGNLDYLSLEQDVFKNNLVLIDSLLPNILAEIVKTFYT..SNLSSIKDLTENINK..TNPLNYD..NQFAHTFYEYKIKRFLTDVALGMTPSKVWNGIY.DATGGYLIVKENGDVLCY.H.IYNRNQFEDYLFQNTKLETASSS..RHEFGKIYPE.NGKTYFKLNLQIRF.......
F0R0L7_BACSH/6-358                 .........TKKEWSELYAFFRLLADGYVYAGTPDVKQNETCCLPVAR.VQREEHDGT.RNYIVGKN.-DVRIWGETIDKR...........--IPREDFGTVADLILQAL..RET.EG..ENVTSpDGVEGFLDEA.AIY.DLEAKT........DDRTDLKVAFYSEE-..--APLTGLCVRSRIGTLYPLLDGGR.TANFKFEQTGI.....KFASPTINKINA...........FGE...E.DD....VLGR.....MQMIERL.GGILKYNDVADKIFRSNLSMLDLHMGRMLGEMTRLMWL..NGITKVSELTEAVKQ..LNPLKIKdeLITKHGYYEYKVKEFLLAIATGMRPAKVYTGIE.SAIDGCLFVTGDGGVLCY.Q.RAFRQVFADFLFQNTRLEKGPVQ..KDKYGYLERE.NGAYYFKLNLKVGL.......
R6RWP7_9BACE/6-358                 .........TKKEWCELYTFFRLLADGRVALGTAEAKAGD-IFWPVAM.IQREEHDGT.RRYYIEEE.-TIRIEGETGVKT...........--MSREDFGIVADLILKAV..KSS.SE..NDVTSpDGVEEFLDEA.AIF.DLEAKT........EDRTDFSIAFWHSE-..--APLRGFNVRSRLSAMNPLLDGGR.AANLKLEQTGIk..faTPTVNKINALP-...........-ES...P.NE....VAER.....MMMIERL.GGVLKYSDVADRVFRSNLLMIDLHFPRVLTEMVRIMHL..DGISRVSELTEIIKQ..MNPLKIKdeLINKHKFYEFKIKQFLMALALGMRPAKIYTGLD.SAVEGILLVDGNGDVLCY.H.KSEKQVMEDFLFLNTRFEKGSLE..KDKYGFLERE.NGVYYFKLNAKIGL.......
H6L4Y2_SAPGL/5-356                 .........NKGEWSEIYTLLKLISDGVLPQGDAHLVATDF-EYIVEA.VYRSEKDGL.KEYHINSD.QKSVLLIDGEEQ-...........VEIPLEEFEAIKTVVLDGI..RQA.PK..GTFLI.EEAIPFLSTI.HCL.SLKAKS........SSKKDIEVLIYDYRV..ARSSKLGFSIKSQLGNPSTLLNASK.ATNFQFWL---.....-PQEVNAESINK...........IST...S.SK....IKKR.....IEAIYEE.VGQLVFTTIQNQTFANNLCLIDSALPQIIAALLLIYYSgrAKSSKITDLVEQLRI..ENPLGFP..EIEGQHFYEYKIKRFLTDVALGMTPNTVWDGRF.DAGGGYIVVRNDGELVCY.H.IYDRNQFEDYLFHNTKLDTPSSS..RHGFGLIYRE.GGENYFNLNIQIRF.......
R5ULD7_9BACE/6-358                 .........TKKEWCELYTFFRLLADGKVVLGTAEAKIGET-SWPIAM.IQREEHDGT.RRYYIEEE.-SVRIEGETGVKS...........--MPREDFGIVADLILQAV..KSS.SE..NDVTSpEGVEEFLDEA.GIF.DLEAKT........EDRTDFSVAFWHPE-..--APVRGFNVRSRLSAMNPLLDGGR.AANLKLEQSGIk..faTPTVNKINALP-...........-ES...P.NE....VSER.....MMLIERL.GGVLKYSDVADRVFRSNLLMIDLHFPRVLTEMIRIMHL..DGISRISELTEVIKQ..MNPLKIKdeLINKHCFYEFKIKQFLMALALGMRPAKIYNGQD.SAVEGILLVGGNGEVLCY.H.KSEKQVMEDFLFRNTRLEKGSLD..KDKYGFLEKE.NGVYYFKLNAKIGL.......
F3ZUA3_9BACE/6-359                 .........NKSEWSELYVFLRLLTDGKLYLGNHRGEKSERSFWPISV.IEREEHDGP.RRYYIEED.-KVRVEGKEDYIK...........--LHRVALAVMADKVLDLI..KSN.NE..EEIECpEDIEKFLDTA.KIL.YLEPET........QDRTDLKISFWSPH-..--KIPTGFIIQSKLAPMRPLLDGGR.SANLKLELTGA....rKFAQPEIENINA...........LET...N.ET....VRDR.....MLLIQEM.DGVLRYSDVADRVFRCNLSMIDLHFARILAEMVRTFHV..EGKSRVYEVMNLIKK..ENPIKIKedLIQKHRFYEYKMKQFLMAATCGMRPAKIFNGED.SAVEGMLVVGSEGQIIGY.H.KDERKAFEDFLYLNTRFIKGSQE..KDKYGFLERE.HGTYFFKLNVKIGL.......
Q5LDN4_BACFN/6-359                 .........TKREWSELYVFFRLLADGKVSLGTPQAKKEDEKYRPIAM.IQREEHDGT.RRYYIEEE.-VIRMEGEKVEKS...........--IPREDFTTVADLILDAI..KNS.SA..DEVTSpDGVEEFLDEA.GIF.DLEART........EDRTDFSIAFWHPE-..--APLAGFNVRSRLSAMNPLLDGGR.AANLKLEQSGIk..faTPTVNKINALP-...........-ES...P.TE....VAER.....MMMIERL.GGVLKYSDVADRVFRCNLLMIDLHFPRVLAEMVRMMHL..DGITRVSELTEQMKI..INPLKIKeeLISKHGFYEFKMKQFLLALALGMRPAKIYNGTD.SAVEGILLVDGKGEVLCY.H.KSEKKTFEDFLYLNSRLEKGAVD..KDKYGFLERE.NGVYYFKLNVKIGL.......
A0A0G0H8K6_9BACT/1-157             ........v---------------------------------------.---------.--------.-------------...........-------------------..---.--..-----.----------.---.------........---------------..-------------------------.-----------.....------------...........---...-.--....----.....-------.---IEFKKVDSDIFEKNLRKIDTVMPEIIAEIILAYYS..DKGSKFPELIQSIMSsgTKILHFN..LTS--EDYAYKIKSLLNNSALGMVPASYWDGNL.RAHGGVIIVREDGEIVCY.H.LYNAEAFRNYLYNNTRIDSPSAT..RHGYGKIYKE.KGDMFIKLNFQIRF.......
R5K7I8_9BACE/6-372                 .........TKRELGELYTFFRLLADGKVFGGTPKAQKDDRKCWPIAL.IQREEHDGT.RRYYIEEE.-DVRIVSGVVEKDgtfiasaekevLSFPRADFGDAAEIILHLL..RNE.PG..EEVEVsEGLEAFLDAV.NIY.DLESKT........EDRTDFSVAFWSVD-..--APLTGFTVRCRLSRMNPLLDGGR.TANLKLEQSGVk..faVPTVNKVNALP-...........-ES...P.TE....VAER.....MMMIERL.GGVLKYSDVADRVFRCNLLMIDLHFPRMLAEMVRTMHL..DGITRVSELTERIKE..MNPLKIKdeLINKHCFYEFKMKQFLLALALGMRPAKIYNGTD.SAVEGLLLTNGEGEVLCY.H.KSERQTFADFLYQNSRFEKGSVD..KDKYGFLERE.NGVYYFKLNVKIGL.......
R6SP07_9BACE/6-358                 .........TKREWGELYAFFRLLADGCVYAGTPEVKRNEGQCLPVAM.VQREEHDGT.RRYIVEKE.-MIHIVGEQMDKR...........--IPREDFGTVADLVLEAI..RNS.RE..DDVTSpDGVEEFLDEV.AIY.DLEAKT........DDRTDFSVAFYQED-..--APLTGFCVRSRLGMMFPLLDGGR.SANFKFEQTGV.....KFAVPTINKINA...........FGE...E.DD....VIGR.....MLMIERL.GGVLKYNDVADKIFRSNLSMIDLHMGRMLAEMTRLMWL..DGITKVSELTEELKK..LNPLKIKdeLISKHGFYEYKIKELLLALATGMRPAKLYNGTD.SAICGFLFVTGEGEVLCY.Q.RAFRQTFADFLFQNSRLEKGSTE..KDKYGYLERE.NGVYYFKLNLKIGL.......
E8UDZ8_TAYEM/10-68                 ...eginys---------------------------------------.---------.--------.-------------...........-------------------..---.--..-----.----------.---.------........---------------..-------------------------.-----------.....------------...........---...-.--....----.....-------.--------------------------------------..---VKLNDILEKLSK..LNPLNLL..---NLRTYEYKFKNFLRSLALGMKPTVPWD---.------------------.-.-----------------------..----------.--------------vkvklme
J5GMI7_9FIRM/5-360                 .........NKWEWSEVYVLLRLLAEEKIYANDNELNKLEDVYFPIIK.VLREENKGE.IKEYTAGE.MISIYIDGAKVKE...........--LPVTEFESEYGNLLNEI..NSKdSK..CTFPV.ESTQNFIDKI.LCY.KIFTPA........TDKSDIKVKIIDADT..VYSPTIGSSMKSELGSSPTLLNAGK.TTNFIYKIVHNhp.dlIREANGIYKVSG...........GKN...H.TD....VRGR.....INKIIKE.NGTLEYRKMNNQIFEDNLVLIDSNMDKIIAETLLYFYK..DGISNCNEMVEKLEQ..ENPMNYG..NVNA---YKYKFKKFLTAVALGMKPATVWDGLD.EATGGYIVVTKEGNVLAY.H.IYNRNHFEEYLLSNTKYETASTS..RHDFGEVYSE.NGEDFIKLNLQVRF.......
R6LHT0_9BACE/6-372                 .........TKRELGELYTFFRLLADGKVSLGTPQVRKDETKCWPVAL.IQREEHDGT.RRYYIEQG.-NVRIVSGVIEKEgafva.adkeeQVIPREDFGGAAEFILELL..KTTsGT..DAIEVpEGLEAFLDAV.NIY.DLEAKT........EDRTDFSVAFWHPE-..--APLTGFNVRCRLSSMNPLLDGGR.TANLKLEQSGVk..faTPTVNKVNALP-...........-ES...P.TE....VAER.....MLMIERL.GGVLKYSDVADRVFRCNLLMIDLHFPRMLAEMVRMMHL..DGIARISELTERIKE..INPLKIKdeLINKHGFYEFKMKQFLLALALGMRPAKIYNGTD.SAVEGILLVDAEGEVLCY.H.KSEHRTFADFLFLNTRLEKGSVD..KDKYGFLEKE.NGVYYFRLNVKIGL.......
E4TNH7_MARTH/5-363                 .........NKGEWSELYVFFQLLSEGKLYSADEKLERNGN-FVEVQS.IKRNDFGKP.KDYKIETS.GNVNIVDSETGNI..........lRAIPRAEIVDITRNLIREL..KQG.KG..KAFGVsSSLEANINSF.MIE.KVSESY........GLKGDINLYIYDPVN..SILTDQKFSIKSLLGSNPTAFNANP.TTNIIYEILTKd..gkPLEENEIIEINE...........IDT...R.HK....YIDR.....VRFILD-.NYSIHYRDYQGEVFKLNLQLIDSSLPEIIASAVLNKYA..FGITKFNEVIEKLND..ANPCNYN..LKHGHSFYEYRLINFMVESSLGMTSATVWSGEY.DVIGGIIIVKGNEEVVSY.H.LIDFNKFKKYLLDNCRLDNPSGS..KMGYGTAYIE.EGKSYIKLNFQVK-v......
R5M6B8_9BACE/6-372                 .........TKRELGELYTFFRLLADGKVSLGTPQVRKDEAKCWPIAM.VQREEHDGT.RRYYIEQE.-NIRIVSGTVEKTgtftv.adkeeQNIPREDFGGAAEIILELL..KTTaGS..DTIEVpEGLEGFLDAI.NIY.DLEAKT........EDRTDFSVAFWHAE-..--APLTGFNVRCRLSSMNPLLDGGR.TANLKLEQSGIk..faTPTVNKVNALP-...........-ES...P.TE....VTER.....MLMIERL.GGVLKYSDVADRVFRCNLLMIDLHFPRMLAEMVRMMHL..DGISRVSELTERIKE..INPLKIKdeLINKHGFYEFKMKQFLLALALGMRPAKIYNGTD.SAVEGILLVNAEGEVLCY.H.KSERQVFADFLYQNTRFEKGSVD..KDKYGFLEKE.NGVYYFRLNVKIGL.......
E6SVX9_BACT6/6-371                 .........TKRELGELYTFFRLLADGKVSMGTSEARKDETKYWLIAL.IQREEHDGT.RRYYIEEE.-GVRIVGGTLEKDgafta.sdkepQLIPRRDFSDAAEIVLHLL..KNV.PG..EEIEIsEGLEAFLDAI.NIY.DLEAKT........GDRTDFSIAFWHSD-..--APLTGFNVRCRLSPMNPLLDGGR.TANLKLEQSGVk..faVPTVNKVNALP-...........-ES...P.AE....VAER.....MLMIERL.GGVLKYSDVADRVFRCNLLMIDLHFPRMLAEMVRIMHL..DGITRVSELTARVKE..MNVLKIKdeLINKHGFYEFKMKQFLLALALGMRPAKIYNGTD.SAVEGILFTDADGGVLCY.H.RSQYRVFADFLYQNSRFEKSSVD..KDKYGFLERE.NGVYYFKLNVKIGL.......
M4YJ48_9EURY/2-148                 .....asdl---------------------------------------.---------.--------.-------------...........-------------------..---.--..-----.----------.---.------........---------------..-------------------ILPGSE.RTSFVYRIEGGm...dDRDRDEMEAMDSgyvmgenwpaiVSD...S.VD....IGHR.....MRYMRKR.NLGLRFLRVESKDYLSELSALDPDLPAILGWMVSEAYL..GGTPRIDDIIDNLES..VNPLRYP..RPAVSGIYREKVGRFLESVGA------------.------------------.-.-----------------------..----------.--------------ged....
R6A1Q5_9BACT/6-358                 .........NKGEWSEIYTLFKLLGEGKVHAGDADMNKLE-LYYPILN.VIREESK-K.YEYKPNVD.QHIVVIDEDGNEF...........ARISMNKFLEESSKLLTEI..KAA.ND..PAFEI.PATESFMTEI.GCS.KLKAPS........KDKADIHIVIHDLRT..NMTPLLGFSIKSQLGSASTLLNAGT.TTNITYKVIGT.....ELSDEDIEEVNS...........IKG...-.--....HLPR.....MQAILDK.GCNLKYSDIEHTIFKNNLLFLDSCMPQFVADCLLINSL.pSSKSSIKECVAEIAK..RNPFNFN..GKNIEAFYAHKMKVLLLDAALGMTPAKEWTGRY.DANGGYLVVRKDGEIVCY.H.FYNRNDVEDYLYNNTRFERASRS..RYGFGYVYREkDGCIYIKLNLQIRF.......
A0A075U4K6_9LACT/6-354             .........NKGEWSELYVFLSVLATGKLFAADEDLNKMEDVYYTVLK.AINQVEKTD.SEYLRDTN.RNVIVIYNNGTHK...........LSIPISEFVKHAPLVLEGI..RNG.KG..RSFEI.PEIESFLETI.LLD.KIKAPS........DSKKDLVFQVHDEYT..GLTPNVGFSVKSYIGGEPTLVNSSG.ATVFTYQTSKS.....FPTSFEA-EVNA...........INT...P.SK....IKDR.....IQKIYEK.QIHLNYSQVSSQIFHRNLQMIDFRLPEILSYLVLSSYF..VKGKRMPEVVKYYSE..----KY-..-EEDRELIEHKIKDFLVATALGMEPNTIWNGLE.DANGGYIVVKNDGEILCY.H.IYDRNKLRSYLYNHTKFDTPSTG..RTGSGMLESI.EDGGMFKLSVQIRF.......
R6CPC7_9BACE/6-358                 .........TKREWSELYAVFRLLSDGQVYAGTPQVKKDETNRLPVAM.IQREEHDGT.RQYIIEGD.-QIRVKSENGEKL...........--FPREDFQTVAELILQAI..KNS.RE..DEVTSpDGVEEFLDEV.AIF.DLEAKT........DDRTDFSVAFYSAD-..--APLTGLVVRSRLSPMFPLLDGGR.SANFKFEQTGI.....KFANPTVNKINA...........EGE...E.DD....VLSR.....MLMIERL.GGVLKYNDVADKVFRSNLSMIDLHAGRLFGEMVRLMWL..DGITKVSELTEEIKK..LNPLKIKdeLITKHSFYEYKVKELLLALMNGMRPAKLYNGTD.SAIAGILYVNTDGEVLCY.Q.RAYRQTLADFLYYNTRLTKGSTE..KDKYGYLERE.NGVYYFKLNLKIE-l......
E8LGK0_9FIRM/1-130                 mlynyfflg---------------------------------------.---------.--------.-------------...........-------------------..---.--..-----.----------.---.------........---------------..-------------------------.-----------.....------------...........---...-.--....----.....-------.--------------------------------------..FSEVDLNKVVERVIQ..DNPAGLK..--RPEIKYPYMVKNFLYAAYCGMTASTLWDGKS.NVNGGFITVCNNGDVLAH.Y.ALESDAFKTYLYNNCYLEFPSTSpnHGNYGVVYKE.FSRYYFRLNFQIRY.......
A6L7D1_BACV8/6-359                 .........TKREWGELYAFFRLLADGYVYAGTPDVKRNEVQKLPVAM.VQREEHDGT.RRYILEDE.ATVRICGEKIDKQ...........--IPREDFAAVAELVFAAV..KES.RE..NDVMSpDGVEEFLDEV.AIY.DLEAKT........DDRTDFYVAFYSIE-..--APLVGFCVRSRLGTMFPLLDGGR.TANLKFEQTGVk..faTPTVNKINAF--...........-GE...E.DD....VAGR.....MLMIERL.GGILKYNDVADKVFRSNLCMIDLHFPRMLGEMLRVMHL..DGISKVSDLTEAIKQ..INPLKIKdeLIHKHSYYEYKMKQFLMALALGMRPAKIFNGID.SAISGFLFVNGNGEVLCY.Q.KADRQVFADFLFVNSRFEKSSTE..KDKYGYLERE.NGVYYFKLNLKIGL.......
W8VRS3_9FLAO/5-357                 .........NKGEWSEVYALFKLLGDKQLFLGNKDIEKLEGLVYPIIK.ILRTENNGK.FDYSIQGE.---IILVSGDEEV...........LKIHISDFKDKALFLLNAI..KQN.KE..RTFSV.PEIEEFMQSI.NCI.SLKASS........YAKTDITIVVHDQRT..NQQPTLGFSIKSQLGSPSTLLNAGK.TTNFIYKIVGA.....NLTENEIEKINS...........IAS...R.SK....IMDR.....IVQIQKN.GGQFDFIKTERQIFSNNLVLIDSLLPEILSQIVFDFYS..SEFSHLTDLVNKTAD..QNPLNFD..IENEHKFYEYKIKRFLTDVALGMMPSQVWTGKY.DATGGYLIVKEDGDILCY.H.IYNRNEFEDYLLNNTKLDTASSS..RHRFGEIYKK.NRELYFNLNLQIRF.......
Q30PG8_SULDN/306-657               .........NKGEWSELFAFIKILLEQKLLLSDKELNPTGD-FFKINK.ITTENLD--.LEFIPVSD.FKIKSIHTKTKEEa.........eIDISSIITDETLTNILNQI..KA-.GS..GTFEI.NDFEIIQTAL.GFS.IVKGGN.......sSQKADIVLDI-EHNT..FVKENEGFGIKSYLGSKPTLLNASG.NTNFMFEIDGL.....--DNSKISEINQ...........IST...A.TK....LRDR.....IVAINKN.GGTFRYLKAEKDTMNYNLKMVDNVLPEIIGYLLMAFYG..NRISNLSDIVNYLCD.yTDILTHL..DIDDKAMLINKLKKFLVDILLGFFAGEKWNGSY.-ASNGTIVVKENGDLITF.H.IINMENLKNYLFENIKLDTPSTS..RHKFGTIIQD.KTKNYFKLNLQLRF.......
R7NP11_9BACE/6-359                 .........TKREWGELYAFFRLLADGYVYAGTPEVKKNEAQRLPVAM.IQREEHDGT.RRYIIESE.ENIHICGEKIDKL...........--VAREDFSAVAELILSAV..KAS.RE..NDVMSpDGVEEFLDEV.AIF.DLEAKT........DDRTDFYVAFYSAD-..--APLTGFCVRSRLSSMFPLLDGGR.TANLKFEQTGIk..faTPTVNKINAF--...........-GE...E.DD....VAER.....MLMIERL.GGVLKYNDVADKVFRSNLSMIDLHFPRMLGEMLRIMHL..DGITRVSELTEVMKQ..VNPLKIKeeLITKHHYYEYKMKQFLLALALGMRPAKLFTGVD.SAVSGFLLVDGSGEILCY.Q.KADRQTFADFLFNNSRFEKGSTE..KDKYGYLERE.NGVYYFKLNAKIGL.......
A6ELS9_9BACT/5-357                 .........NKGEWSEIYTLFKLLGDKELFLGNKDIEKLEGLVYPIIK.ILRSENNGD.FEYSIKDE.---IIIISGNEEV...........VKIPISQFKNKAQLLLDAI..KIN.KE..RTFSV.PNIENFMQSI.NCM.SLKAGS........SSKTDITIVVHDQRT..KQQPTLGFSIKSQLGSPSTLLNAGK.TTNFIFKLKDL.....NLDRKEIDQINA...........IST...R.SK....IKDR.....ISEIIDK.GGEFEFIKTEHKIFSNNLILIDSLLPKLLSNIVLDFYS..TEFSHLKDLTKEIAK..KNPLEFD..IENEHKFYDYKIKRFLTDVALGMMPSKVWSGKY.DATGGYLIVKDNGEVLCY.H.IYNRNQFEEYLFNNTKLETASSS..RHGFGEVYYK.NGELYFNLNLQIRF.......
R7A9M9_9BACE/6-358                 .........TKREWGELYAFFRLLADGYVYGGTPDVKKNETLRLPVAM.VQREEHDGT.RQYILEKD.-SIHLKGEHIDKR...........--IPREDFATVAELIYAAI..RQS.RE..DDVTSpDGVEEFLDEV.AIF.DLEART........DDRTDFSVAFYSVD-..--APLTGFCVRSRLGMMIPLLDGGR.TANFKFEQTGVk..faTPTVNKINAE--...........-GE...E.DD....VVSR.....MLMIERL.GGVLKYSDVADKIFRSNLSMIDLHMGRLLAEMTRLMWL..DGLTKVSDLTEELKK..LNPLKIKdeLITKHRFYEYKVKELLLALAMGMRPAKLYNGTD.SAIAGFLFVTGDGEVLCY.Q.RAFRQTFADFLFQNSRLEKGPTE..KDKYGYLERE.NGVYYFKLNLKIGL.......
#=GC seq_cons                      .........sKtEWuElYshh+LLu-GplhhGsschp+.-s.haPlhh.I.R-EpcGp.hpYhlppc..plhlhspphpcp.............lspp-FtphAchlLptl..+ps.pp..pshps.sslEpFLcpl.slh.sLcApo........sD+oDhplshac.c.....sPhhGFsl+S+LushssLLsuG+.ssNhhac.sGl.......sssclstls.............ps.....sc....ltcR.....hhhIcch.GGsL+YsclssclF+sNLhhIDhphP+lLAEhlthhah..sulo+lsELsEplpp..hNPLclc..Lhsp+tFYEaKhKpFLhAlALGMpPuKlasGps.sAssGhllVpscG-VLCY.H.hhp+phFp-aLapNT+hEpuSss..+ccaGhl.+E.NGhaYhKLNlpIth.......
//
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