GenomeNet

Database: Pfam
Entry: RE_NgoPII
LinkDB: RE_NgoPII
Original site: RE_NgoPII 
#=GF ID   RE_NgoPII
#=GF AC   PF09521.8
#=GF DE   NgoPII restriction endonuclease
#=GF AU   Bateman A
#=GF SE   Bateman A
#=GF GA   25.00 25.00;
#=GF TC   40.10 40.10;
#=GF NC   18.80 18.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR019046;
#=GF CC   This family includes the NgoPII (recognises and cleaves GG^CC)
#=GF CC   restriction endonuclease.
#=GF SQ   19
#=GS F0S2I4_DESTD/5-277      AC F0S2I4.1
#=GS D5ERM8_PRER2/4-268      AC D5ERM8.1
#=GS K0C131_CYCSP/2-261      AC K0C131.1
#=GS G8X6Y9_FLACA/2-263      AC G8X6Y9.1
#=GS A0A0H4IT76_NEIG1/3-153  AC A0A0H4IT76.1
#=GS I3CCM7_9GAMM/2-265      AC I3CCM7.1
#=GS D1B3R6_SULD5/2-265      AC D1B3R6.1
#=GS A8MHW4_ALKOO/3-264      AC A8MHW4.1
#=GS K9VY48_9CYAN/2-266      AC K9VY48.1
#=GS K9RKZ4_9CYAN/2-259      AC K9RKZ4.1
#=GS A6EU95_9BACT/2-262      AC A6EU95.1
#=GS I4AHT4_FLELS/2-262      AC I4AHT4.1
#=GS X2H1I1_9GAMM/3-266      AC X2H1I1.1
#=GS A0A0G0MVU1_9BACT/2-262  AC A0A0G0MVU1.1
#=GS D5VBE5_MORCR/1-47       AC D5VBE5.1
#=GS A0A0G0CFJ1_9BACT/3-264  AC A0A0G0CFJ1.1
#=GS V5XUW6_ENTMU/3-264      AC V5XUW6.1
#=GS R7P700_9CLOT/3-265      AC R7P700.1
#=GS A0A0G1RJ76_9BACT/2-266  AC A0A0G1RJ76.1
F0S2I4_DESTD/5-277                 tiidfivnlssyikafgyglpsid--------------------VSVYR..SRVNSSGEALEHFVRDMFAGTYNLESESEKIKIFSEVFSYLGNQNNPPDLMIKGGDAVEVKKIESDGlrKKIPLNSSYPKNKLYRTDPRITNSCRKAE...DWEEKDLIYSIGVVKRML..IHRLYMIYGDLYAADKEVYERCFNVIKKAVKHSltdIGLEMKKTKELAKIDRVDPLGITDLRIRGMWNILSPKGT..FGDI.NGIEEFKdeNNKVLILLRKEKLQRILQETEEEI----..------------lekyfelreegfirer
D5ERM8_PRER2/4-268                 .......................y-NIITAIINIIKDNRRVIGNSPNSN..NRLHSLGEPLEEYIKDAFSNSLGLSGVD-KTRKRAEALSYGGGKNNPPDAVLKRGAAIEVKKVESIG..N-INLNSSYPKSHLFKNDSKISKACREIEn.gDWDVKDIIYAIGCVEKKKnnLKSLALVYGSVYCASKECYENVFNSVKQSIEES...SELDLEETKELAHINAVDPLRITFFRARGMWGISHPFKVgsFADI.YRYDESN..-FELMAIIPSDKYNSFENID--ELSELSqrIDNLTIEDTFV-q...............
K0C131_CYCSP/2-261                 ........................SNIIKAIINIANEPIVQLRDSYTSR..NTINNIGQALEAYMQDAFANTISEPSPQKRNERINEVFSYLGNQNNPPDIILKDGDAIEVKKIQSKG..AAIALNSSYPKSKLHSDDSKITDACRDCE...DWTAKDIIYAIGVTSDQN..LKHLWLVYGDCYAASREIYTRIGKTIKEGVKEI...EDIEFSETKELGRVNRVDPLGITNLRIRGMWHIDNPLKV..YKDY.YEANETK..TFSLACIIREDKFLSFNSSDIDSLYS--..HNDIAIKDIEIK................
G8X6Y9_FLACA/2-263                 ........................TNILDAIYNISLIQDLSIDEIIFGN..NRANNMGEGLESFIKDSFANTFNEDNNRILSEKYSVFFSYEGSKNNPPDLMIKNGDALEIKKVESLT..SELQLNSSHPKSKLYSSSPLINKHCKNCE...IWDEKDFIYTIGHIPNGTkkLSSLWFVYGSIYSADEEIYLSIKNELAKSLEEN...QNLHFSVTNEIGRLNFVDPLKITNLRIRGMWLLQPPFKV..FKDY.YEYKKES..NFQCFAFIPNDKYISFPIESRNKVEN--..SNNIKIENIKVK................
A0A0H4IT76_NEIG1/3-153             ...........aclqkpakmrkng-------------------------..-------------------------------------------------------------------..-----------------------------...--KRKTLSIIVGVVDKKK.nLKHLAMVYGIDYCADAECYLKIKNQIKEGIGNI...GGIQFAETKELGRVNRIDPLNITYLRVRGMWGIENPWFV..FNYI.YQRNMEK..SFNFMAIINEDKWNSFNNTD--KLLAIQ..DSKLAISDIKIK................
I3CCM7_9GAMM/2-265                 ........................TNLIIALKNLIQNPITDLNSFYQGS..NRANSMGDALETYIKDIFCNSLHLSDTE-KDKLYSQNFSYIGNQNNPPDIIIKGGDAIEVKKIESIS..SAIALNSSYPKSKLFRNDSRITNACKECEgavSWEQKDIIYIIGVAPKST..LKALWFVYGDCYAAESEIYHRVANKISQGISEI...SGVELVATNELAKVKKVDPLGITDLRVRGMWHIENPIKV..FQHI.ASITELH..QLTVHTILLEEKYNTFPQSDREQLEQLQ..SEHFTIRNVAI-r...............
D1B3R6_SULD5/2-265                 ........................TNILSAFRTIISNYQTNVQHVTNGS..NRANNMGDGLEAFIKDAFANTFNETNEQTKLEVFSRIYSYSGNKNNPPDLILQNSDAIEIKKLESAS..TAIALNSSYPKAKLFSNSTMITTACRTCE...AWSEKDMLYAIGNVPKTTnqLKSLWLVYGDCFCADKEVYERIQQTISSGITSI...PNVEFTQTNELGKVKKVDPLGITDLRIRGMWHIENPTKI..FNYL.YHYDETA..TFQLICLMKKEKYEALPLEDRNAIENLS..NLHVTLSDIRIK................
A8MHW4_ALKOO/3-264                 ........................TNIIRAIINLVNTPVVELKEYADSH..NRVNSMGGALEEYIKDIFAGTVGEIDEKKRLLKIQECFSYLGNQNNPPDSMLWGGDAIEVKKIESKD..AQLALNSSYPKAKLFSNSKMIKKACRACE...DWTVKDMIYTVGVVKDSK..LSSLCMVYGIDYAADAETYEQIKEVIKDGVESI...NGVEFAETKELGRVNRVDPLGITYLRVRGMWGIENPFKV..FNYV.YERDSSK..NFNFMALINNEKYDTLEYTD--ELEKLVgvKEGLELKEVNIK................
K9VY48_9CYAN/2-266                 ........................TNILQAINTIINNPIPDLVSYYQSKsqNKINAIGEALEEFIKDVFADTISETDTIKKSKKYEQVFSHQGSQNNPPDLMIKNGDAIEVKKINKIG..SGIALNSSYPTAKLYQDSPMITADCRNCE...TWTEKDIIYAIGCTPEQK..LRLLWFVYGDCYAASKETYKRISQQIAIGVNQI...PNVVFSKTKELGKVNQVDPLKITDLRIRGMWSIKNPLKV..YKYInLDYDNSS..QFQLNVVMRQTKYLSFPEKERIKLESLS..KPGFSIADNKIK................
K9RKZ4_9CYAN/2-259                 .......................a-DILQAIKAIIDNTIPDIVSYSQGK..NRINSAGDALEDFIKDIFSEALKDSDLTLKNKKYSEAFSYIGNQNNPPDIILKNGDAIEVKKIESLK..SSIALNSSYPKSKLYFDEPMITNSCRNCE...DWQEKDIIYAIGVVKEKK..LQLLWLIYGDCYAADREIYQRIRNKINSGITEI...PNVEFSETKELGRVNKVDPLGITYLRIRGMWGIKNPVVV..YDYL.FENLDIN..TFKLIVVMKEEKYLSFPYEKRMLLEGIS..NQNFTIR-----k...............
A6EU95_9BACT/2-262                 ........................TNILEAIYNIVNHKNFAIREFYSGR..NRANSMGEALENYIKDAFADTFDSDDEQSRLKTYNQEFSWLGSQNNPPDIMIKGGDAIEVKKTQSAN..SSLALNSSYPKTDLRHTSPMITSECRDCE...EWTVKDLIYCVGHTSDTN..IKSLWMVYGSSYAAKHETYQRIKTTISDGIKTI...PDVVFADTKELGRVNQVDPLGITNLRIRGMWQIENPRKV..FNYL.HEPTDKD..-FELVCIIPLEKYNSFPNESKSKLEGIT..EKGFSIEDKQIK................
I4AHT4_FLELS/2-262                 ........................TNILEAIYAIIQNPIFEIKSFYTGR..NRANSVGDALENYIKDAFANSFHINDEKERMKLFNENFSWLGSQNNPPDIMIKGGDAIEVKKTQTAN..TNLALNSSYPKSNINSSSPMITQSCKNCE...EWTEKDLIYCVGHTTDTT..LKSLWMVYGNIYAAGHETYERIKNTISEGIDTI...PNVEFAETKELGRVNKVDALGITNLRIRGMWQIQNPRKV..FSYL.HIPTEKK..-FELICIIPTSNYNSFDKSSKNKIESIN..KVGFTIQDEKVK................
X2H1I1_9GAMM/3-266                 ........................TNLIKAILHLIKLPAIQISEMSDGK..NRVNNQGRGLEEFIIDLFCGTVNEPNERIRLEKRNELFSYIGNQNNPPDAMINAGDAIEIKKIETAG..AAIALNSSYPKAKLYSNSSMLAKACISCE...DWDEKDMIYVIGQIYKHS..LKSLCFVYGVDYAASLEIYERIKLKIKQGILTI...DGVEFSETKELGRVNKVDPLGITNLRIRGMWHIDNPIKV..FNYI.YKPKEIS..SFNLMVLINNDKYLTFSEEDRNKLEKAEkyLENFMIEDVMIK................
A0A0G0MVU1_9BACT/2-262             ........................TNLLIALKNLIMIQSADIEAYSKSS..NRANSMGDALEIYIRDLFCGSSNAKREE-KDLIYNNHFSYLGNQNNPPDLIIKGGDALEVKKIESLR..SGIALNSSYPKDKLYVDSPMITKDCRLCE...AWKEKDIIYCIGIIKNNR..LIALWFVYGNCYAANKDIYERIKTRISTGLNEL...DGVELSDTEELGRVNKVDPLGITYLRIRGMWGIENPAKV..FDYI.AGIESNK..ELTVNAIMLKEKYDSFPEKDRVGLEKLV..NSSLSISDIKIK................
D5VBE5_MORCR/1-47                  .......................m-NIINAIFNIVTDFSYELTRDLHGL..NRANQMGGALEEWVKDIFAK-----------------------------------------------..-----------------------------...------------------..---------------------------------...---------------------------------------..----.-------..----------------------------..------------ly..............
A0A0G0CFJ1_9BACT/3-264             ........................TNILIALKNLVKDPVTNLVSRYRGV..NRANSMGDALEFYIKDLFCNSLNEENLVKKDEAYSKYFSYLGNQNNPPDIMIKSGDAIEVKKVEGLD..AGIALNSSYPKDKLFSDSSMITTACRNAE...NWREKDLIYTIGVVKEDK..LKALWFIYGNCYSANKEVYERIRDKISKGVNEL...QSVEFSETNELGRVNKVDPLGITYLRIRGMWGIENPIKV..FNYV.APVNRNV..ELSVNALMLKEKYLSFPEKDRKNLEKLV..GDKFTIKDIKIK................
V5XUW6_ENTMU/3-264                 .......................v-NIIDAIINIVHSGVYDLQDSYVRS..NRANSMGDALEKYIIDSFSGLINEFDENIRMNKIGEVFSYLGNDSNPPDAMLRGGAGIETKKIESRG..STLQLNSSHPKSKLYVTDPRINRHAVSAE...EWDIKDFIYAIGWVQQKK..LKELALIDASVYCADTSIYSDTFEAIKLGIASI...PNVDFSPTKELGRVNKVDPLGITNLRIRGMWLLENPFNV..FRYI.YIPEENK..SFNLFGLVSEEKYNSFSNTD--ELEKLSneKQSLNIVDVQVK................
R7P700_9CLOT/3-265                 ........................SNILKMINNISLYGSNEIIRDYVGN..NRANNEGNALELFVKDAFCNSFGLEDEEAK-KKYNEVFSYIGNNKNPPDAIIRNGDAIEVKK-NNQS..NKVQLNSSYPSKKLNNNSMMINKRCRECEgvnGWTEKDLVYFVGELGNNK..LKYLTITYGDCFAANEDVYFSVKNTIKEKVNGI...EGFTFEETNELGKINNIDKLSITDLRIRGMWIMDNPRSI..FSYV.LDEYNNVlsDMNVFLIMLTEKYNSFSSEDRALVEQ--..NNLLHIHDIRIK................
A0A0G1RJ76_9BACT/2-266             ........................TNILNAILNINHFRQNNLKGYATQY.lNRINAVGEQLEYYVKDAFTNSFIVDQSQ-KESAYQRVFAYLGNQNNPPDAILLQGDAFEIKKMGTPR..SILALNSSYPKDKLYRTDNRLTAECKRCDg.gRWLKKDIFYVVGYVASGI..LKHLFLIQGLCYAADKSIYENMHANLKSQIGSIirdAGLEAVNTVELGRVRRVDPLGITEFRLRGMWEIENPMSV..FSGI.YEFNKEH..NFSLCAILKRDKYALYSAVDRNTIEH--..TENISVSDVSV-r...............
#=GC seq_cons                      ........................oNIlpAIhNIlpp..hplpphhpup..NRsNuhG-ALEpaIKDhFusohs.pspp.+.ctaschFSYlGNQNNPPDhhl+sGDAIEVKKlpohs..utlALNSSYPKsKLapssshIopsC+pCE...sWpcKDlIYsIGhltcpp..LKpLahVYGssYAAscElYp+IpspIppGlppI...ssl-FucTcELGRVN+VDPLGITpLRIRGMWtI-NPhKV..FsYl.aphpcpp..pFplhsll.p-KYtSFsppD+.pLEpl...ppshsIpDlplK................
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