GenomeNet

Database: Pfam
Entry: RE_NgoPII
LinkDB: RE_NgoPII
Original site: RE_NgoPII 
#=GF ID   RE_NgoPII
#=GF AC   PF09521.7
#=GF DE   NgoPII restriction endonuclease
#=GF AU   Bateman A
#=GF SE   Bateman A
#=GF GA   25.00 25.00;
#=GF TC   40.10 40.10;
#=GF NC   18.30 17.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR019046;
#=GF CC   This family includes the NgoPII (recognises and cleaves GG^CC)
#=GF CC   restriction endonuclease.
#=GF SQ   13
#=GS F0S2I4_DESTD/5-277  AC F0S2I4.1
#=GS I4AHT4_FLELS/2-262  AC I4AHT4.1
#=GS D5ERM8_PRER2/4-268  AC D5ERM8.1
#=GS X2H1I1_9GAMM/3-266  AC X2H1I1.1
#=GS G8X6Y9_FLACA/2-263  AC G8X6Y9.1
#=GS K0C131_CYCSP/2-261  AC K0C131.1
#=GS D5VBE5_MORCR/1-47   AC D5VBE5.1
#=GS V5XUW6_ENTMU/3-264  AC V5XUW6.1
#=GS D1B3R6_SULD5/2-265  AC D1B3R6.1
#=GS R7P700_9CLOT/3-265  AC R7P700.1
#=GS A8MHW4_ALKOO/3-264  AC A8MHW4.1
#=GS K9VY48_9CYAN/2-266  AC K9VY48.1
#=GS K9RKZ4_9CYAN/2-259  AC K9RKZ4.1
F0S2I4_DESTD/5-277             tiidfivnlssyikafgyglpsid--------------------VSVYR..SRVNSSGEALEHFVRDMFAGTYNLESESEKIKIFSEVFSYLGNQNNPPDLMIKGGDAVEVKKIESDGlrKKIPLNSSYPKNKLYRTDPRITNSCRKAE...DWEEKDLIYSIGVVKRML..IHRLYMIYGDLYAADKEVYERCFNVIKKAVKHSltdIGLEMKKTKELAKIDRVDPLGITDLRIRGMWNILSPKGT..FGDI.NGIEEFKdeNNKVLILLRKEKLQRILQETEEEI----..------------lekyfelreegfirer
I4AHT4_FLELS/2-262             ........................TNILEAIYAIIQNPIFEIKSFYTGR..NRANSVGDALENYIKDAFANSFHINDEKERMKLFNENFSWLGSQNNPPDIMIKGGDAIEVKKTQTAN..TNLALNSSYPKSNINSSSPMITQSCKNCE...EWTEKDLIYCVGHTTDTT..LKSLWMVYGNIYAAGHETYERIKNTISEGIDTI...PNVEFAETKELGRVNKVDALGITNLRIRGMWQIQNPRKV..FSYL.HIPTEKK..-FELICIIPTSNYNSFDKSSKNKIESIN..KVGFTIQDEKVK................
D5ERM8_PRER2/4-268             .......................y-NIITAIINIIKDNRRVIGNSPNSN..NRLHSLGEPLEEYIKDAFSNSLGLSGVD-KTRKRAEALSYGGGKNNPPDAVLKRGAAIEVKKVESIG..N-INLNSSYPKSHLFKNDSKISKACREIEn.gDWDVKDIIYAIGCVEKKKnnLKSLALVYGSVYCASKECYENVFNSVKQSIEES...SELDLEETKELAHINAVDPLRITFFRARGMWGISHPFKVgsFADI.YRYDESN..-FELMAIIPSDKYNSFENID--ELSELSqrIDNLTIEDTFV-q...............
X2H1I1_9GAMM/3-266             ........................TNLIKAILHLIKLPAIQISEMSDGK..NRVNNQGRGLEEFIIDLFCGTVNEPNERIRLEKRNELFSYIGNQNNPPDAMINAGDAIEIKKIETAG..AAIALNSSYPKAKLYSNSSMLAKACISCE...DWDEKDMIYVIGQIYKHS..LKSLCFVYGVDYAASLEIYERIKLKIKQGILTI...DGVEFSETKELGRVNKVDPLGITNLRIRGMWHIDNPIKV..FNYI.YKPKEIS..SFNLMVLINNDKYLTFSEEDRNKLEKAEkyLENFMIEDVMIK................
G8X6Y9_FLACA/2-263             ........................TNILDAIYNISLIQDLSIDEIIFGN..NRANNMGEGLESFIKDSFANTFNEDNNRILSEKYSVFFSYEGSKNNPPDLMIKNGDALEIKKVESLT..SELQLNSSHPKSKLYSSSPLINKHCKNCE...IWDEKDFIYTIGHIPNGTkkLSSLWFVYGSIYSADEEIYLSIKNELAKSLEEN...QNLHFSVTNEIGRLNFVDPLKITNLRIRGMWLLQPPFKV..FKDY.YEYKKES..NFQCFAFIPNDKYISFPIESRNKVEN--..SNNIKIENIKVK................
K0C131_CYCSP/2-261             ........................SNIIKAIINIANEPIVQLRDSYTSR..NTINNIGQALEAYMQDAFANTISEPSPQKRNERINEVFSYLGNQNNPPDIILKDGDAIEVKKIQSKG..AAIALNSSYPKSKLHSDDSKITDACRDCE...DWTAKDIIYAIGVTSDQN..LKHLWLVYGDCYAASREIYTRIGKTIKEGVKEI...EDIEFSETKELGRVNRVDPLGITNLRIRGMWHIDNPLKV..YKDY.YEANETK..TFSLACIIREDKFLSFNSSDIDSLYS--..HNDIAIKDIEIK................
D5VBE5_MORCR/1-47              .......................m-NIINAIFNIVTDFSYELTRDLHGL..NRANQMGGALEEWVKDIFAK-----------------------------------------------..-----------------------------...------------------..---------------------------------...---------------------------------------..----.-------..----------------------------..------------ly..............
V5XUW6_ENTMU/3-264             .......................v-NIIDAIINIVHSGVYDLQDSYVRS..NRANSMGDALEKYIIDSFSGLINEFDENIRMNKIGEVFSYLGNDSNPPDAMLRGGAGIETKKIESRG..STLQLNSSHPKSKLYVTDPRINRHAVSAE...EWDIKDFIYAIGWVQQKK..LKELALIDASVYCADTSIYSDTFEAIKLGIASI...PNVDFSPTKELGRVNKVDPLGITNLRIRGMWLLENPFNV..FRYI.YIPEENK..SFNLFGLVSEEKYNSFSNTD--ELEKLSneKQSLNIVDVQVK................
D1B3R6_SULD5/2-265             ........................TNILSAFRTIISNYQTNVQHVTNGS..NRANNMGDGLEAFIKDAFANTFNETNEQTKLEVFSRIYSYSGNKNNPPDLILQNSDAIEIKKLESAS..TAIALNSSYPKAKLFSNSTMITTACRTCE...AWSEKDMLYAIGNVPKTTnqLKSLWLVYGDCFCADKEVYERIQQTISSGITSI...PNVEFTQTNELGKVKKVDPLGITDLRIRGMWHIENPTKI..FNYL.YHYDETA..TFQLICLMKKEKYEALPLEDRNAIENLS..NLHVTLSDIRIK................
R7P700_9CLOT/3-265             ........................SNILKMINNISLYGSNEIIRDYVGN..NRANNEGNALELFVKDAFCNSFGLEDEEAK-KKYNEVFSYIGNNKNPPDAIIRNGDAIEVKK-NNQS..NKVQLNSSYPSKKLNNNSMMINKRCRECEgvnGWTEKDLVYFVGELGNNK..LKYLTITYGDCFAANEDVYFSVKNTIKEKVNGI...EGFTFEETNELGKINNIDKLSITDLRIRGMWIMDNPRSI..FSYV.LDEYNNVlsDMNVFLIMLTEKYNSFSSEDRALVEQ--..NNLLHIHDIRIK................
A8MHW4_ALKOO/3-264             ........................TNIIRAIINLVNTPVVELKEYADSH..NRVNSMGGALEEYIKDIFAGTVGEIDEKKRLLKIQECFSYLGNQNNPPDSMLWGGDAIEVKKIESKD..AQLALNSSYPKAKLFSNSKMIKKACRACE...DWTVKDMIYTVGVVKDSK..LSSLCMVYGIDYAADAETYEQIKEVIKDGVESI...NGVEFAETKELGRVNRVDPLGITYLRVRGMWGIENPFKV..FNYV.YERDSSK..NFNFMALINNEKYDTLEYTD--ELEKLVgvKEGLELKEVNIK................
K9VY48_9CYAN/2-266             ........................TNILQAINTIINNPIPDLVSYYQSKsqNKINAIGEALEEFIKDVFADTISETDTIKKSKKYEQVFSHQGSQNNPPDLMIKNGDAIEVKKINKIG..SGIALNSSYPTAKLYQDSPMITADCRNCE...TWTEKDIIYAIGCTPEQK..LRLLWFVYGDCYAASKETYKRISQQIAIGVNQI...PNVVFSKTKELGKVNQVDPLKITDLRIRGMWSIKNPLKV..YKYInLDYDNSS..QFQLNVVMRQTKYLSFPEKERIKLESLS..KPGFSIADNKIK................
K9RKZ4_9CYAN/2-259             .......................a-DILQAIKAIIDNTIPDIVSYSQGK..NRINSAGDALEDFIKDIFSEALKDSDLTLKNKKYSEAFSYIGNQNNPPDIILKNGDAIEVKKIESLK..SSIALNSSYPKSKLYFDEPMITNSCRNCE...DWQEKDIIYAIGVVKEKK..LQLLWLIYGDCYAADREIYQRIRNKINSGITEI...PNVEFSETKELGRVNKVDPLGITYLRIRGMWGIKNPVVV..YDYL.FENLDIN..TFKLIVVMKEEKYLSFPYEKRMLLEGIS..NQNFTIR-----k...............
#=GC seq_cons                  ........................oNIlpAIhsIlpsshhplpchhsup..NRsNshG-ALEcaIKDsFAsohs-sspph+.cKhsEsFSYlGNpNNPPDhhl+sGDAIEVKKlEStu..stlsLNSSYPKuKLasssshIspuCRsCE...-WsEKDhIYsIGhltcpp..L+pLhhVYGssYAAscElYpcIppsIppGlppI...ssl-FucTKELG+VN+VDPLGITsLRIRGMWtIcNPhKV..FsYl.ac.c-pp..sFpLhsllpp-KY.SFspp-c.clEph...ppshpIpDhplK................
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