GenomeNet

Database: Pfam
Entry: RE_XamI
LinkDB: RE_XamI
Original site: RE_XamI 
#=GF ID   RE_XamI
#=GF AC   PF09572.8
#=GF DE   XamI restriction endonuclease
#=GF AU   Coggill P
#=GF SE   Bateman A
#=GF GA   25.00 25.00;
#=GF TC   55.20 54.70;
#=GF NC   23.20 19.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   415144
#=GF RT   A new restriction endonuclease from Streptomyces albus G. 
#=GF RA   Arrand JR, Myers PA, Roberts RJ; 
#=GF RL   J Mol Biol. 1978;118:127-135.
#=GF RN   [2]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR019072;
#=GF CC   This family includes the XamI (recognises GTCGAC but cleavage
#=GF CC   site unknown) restriction endonuclease.
#=GF SQ   23
#=GS G5F5M4_9ACTN/1-208       AC G5F5M4.1
#=GS W8X8B5_CASDE/1-199       AC W8X8B5.1
#=GS K9W514_9CYAN/53-308      AC K9W514.1
#=GS W5TLJ5_9NOCA/56-291      AC W5TLJ5.1
#=GS A5USP4_ROSS1/56-179      AC A5USP4.1
#=GS I4EKI5_9CHLR/52-303      AC I4EKI5.1
#=GS D2UFF2_XANAP/54-290      AC D2UFF2.1
#=GS B4VV75_9CYAN/1-208       AC B4VV75.1
#=GS D8FT64_9CYAN/53-308      AC D8FT64.1
#=GS K9U9Q7_9CYAN/53-309      AC K9U9Q7.1
#=GS E1T7P5_BURSG/88-319      AC E1T7P5.1
#=GS D0WLN5_9ACTO/59-290      AC D0WLN5.1
#=GS A1BGJ7_CHLPD/15-270      AC A1BGJ7.1
#=GS K9T9V4_9CYAN/53-309      AC K9T9V4.1
#=GS L7LQC5_9ACTN/57-290      AC L7LQC5.1
#=GS U5QC54_9CYAN/53-306      AC U5QC54.1
#=GS A0A0D5LT20_9RHIZ/61-291  AC A0A0D5LT20.1
#=GS E5AMB6_BURRH/54-290      AC E5AMB6.1
#=GS E4NPA7_HALBP/50-271      AC E4NPA7.1
#=GS J1GS95_9ACTO/55-288      AC J1GS95.1
#=GS A0A073CCG9_PLAAG/62-317  AC A0A073CCG9.1
#=GS U1YI14_9BURK/53-311      AC U1YI14.1
#=GS D4JUQ2_9FIRM/53-309      AC D4JUQ2.1
G5F5M4_9ACTN/1-208                  ..............m----..-------.--------.-----------------------------E..-EGRLPTRNRQRFIDEQIPALLGVIDRLLDRQLINWLGYEHDPLSMDMYVAKSVVADRLCGTT.SDPIIRNAQEAR......QLAVIAAYLEPKGYTLIDDA.S-VGPF.EM..PRGTFAYHKNVRMYqnarDDS-NgyVNTPVDVVIMPMDPS-IDTPLLVECKSAGDFANTNKRRKEEDTKVTQLRST.YGD..-VTL.YLFLCGYFDSTYLGYEAA.NHMDWVW.......
W8X8B5_CASDE/1-199                  ..............m----..-------.--------.------------------------------..---------SSVKADQELEKIAAVIERLADPDIFVWLNRAASATKAEIHRAATIIADRLCGAV.TNPIIRNAQEQR......QLAVIQAYLEQRGYRRLHPG.DGIKFN.SM..PSGTFSFRMNVPIK...qTNGVQ.sINIPIDAVIMPKAAKRGDLPLFFEAKSAGDFTNTNKRRKEEAVKMAQLRHT.YGP..NVRF.NLFLCGYFDSGYLGYEAA.EGIDWAW.......
K9W514_9CYAN/53-308                 ..............t-NLT..NITPDVL.RQHPSVLP.ILRMAAAPPIARDRLIGLAGVSPNLVKNME..EQQRLPPRMNSATLDAELMKISQIIMRLTDKDIFSWLDTRQPPTDAEVHRAATIVADRLCGAV.SDPIIRNAQERR......QLATIRQWLEQRGYSYIGAG.TGLSFE.RI..QPGTFAFRLNIPVL...lQGGSK.qVNIPIDVVVMPLQSNFGQLPLLIEAKSAGDYTNPNKRRKEEAIKIAQLKSN.YGD..NVRF.ILFLCGYFDSGYLGYEAA.EGIDWLW.......
W5TLJ5_9NOCA/56-291                 ...........vdls-QLA..DQASDLL.TQSEDTLT.TIRYLASPPISADDLKELAE------TTLS..-RSRLIAEGGV-----AARRVIETVLLGLDRNRFPWIGEDREPTDAERN-AAVISTAALIAT-.----QKVQTARRneakdeQESLAASYLVSQGFRQVPTR.KIV--S.VM.dMPQPGEFCRESMF-....--GDR..---KADLVVRVWDGR----IMPIECKVSNSSTNSVKRLNNDAAVKAKAWIEqFGN..RTTIpAALLSGVFKVHNLESAQT.AGLTIIW.......
A5USP4_ROSS1/56-179                 ..............d-DLR..RLDVTTL.RSNPGILP.TLRMCTAPPLAVDRLVGLAGVSKNLIERME..-QGNLPGKTTSADLDRALTKICDILSQLLDRDIFPWLVNGTALDDRERDRSATIIADRLCSAV.ANPIIRNAQEQ-......--------------------.------.--..--------------....-----..---------------------------------------------------.---..----.------------------.-------lg.....
I4EKI5_9CHLR/52-303                 ...............NDLE..SIAPETL.LVSPQVLP.ILRMCTAPPLARDRLVGLSNTTKNLVGNLE..-AGRLPPRMPKDQLQAALTKISETILRLLDVDLFPWLSEHSLPSEQMRDRSAMVVADRLTGAN.ADPLIRNAQEQR......QLDKLRQFLVERGYKEEQPP.PGSLPT.AM..PRGTFWFRLNVRV-....--GAEleVNIPIDAVIQPKGAPLGAMPILIEAKSAGDFTNVNKRRKEEATKNRQLQER.YGD..QTKI.ILLLAGYFDAPYLGYEAA.EGLDWVW.......
D2UFF2_XANAP/54-290                 .............sd--LNpgAITDDNLaEAYGLGLGeALRYLAGPPISDDDLQVIAD-----VESIA..-PGVLKKNSEA------LRKVFEVIERVIDPHRFPWMEAGGAPTDQQRE-AALLASSVLLAA-.----QRIATERRnegkqnQETTVKDYLRSLGFTEAPAV.A---IN.TIvkGPQAMQFCAECQL-....--GER..---KADVVVRLHDTR----LMAIECKVSNSATNSVKRLNNDAAVKAEYWIKqFGT..AQVVpAAALAGVFKVLNLEQAQT.RGLSLFW.......
B4VV75_9CYAN/1-208                  ...............----..-------.--------.----------------------------ME..KEKKLPIRLQGNALDIELRKIGKIIERMADPDIFTWLNRSESPSQTDIYRAATIVADRLCGSV.TNPIIRNAQERR......QLAAIQNWLETRQYRKLVGQ.DGVKFD.QM..PPGTFCFRMNVPIN...lETGKV..INIPVDVAIKPKSSSMDELPVFLEAKSAGDFTNVNKRRKEEAIKMSQLRST.YGD..QVQF.NLFLCGYFDSGYLGYEAA.EGIDWVW.......
D8FT64_9CYAN/53-308                 ..............a-NLT..NITSALL.QQHPEVLP.ILRMAAAPPIARDRLIGLAGVSPNLVKNME..EKQRIPPRADIATLDAELTKISQIIARLLDKDIFPWLESRQQPTDSEVQRAATIVADRLCGAI.SDPIVRNAQERR......QLTMIRQWLEQRGYSYVRGG.AGLSFE.TM..QPGTFSFRLNIPVL...lQSGTK.qINIPIDVALVPIDSSPGEFPLLIEAKSAGDYTNPNKRRKEEAIKMTQLRSN.YGN..NVRF.ILFLCGYFDSGYLGYEAA.EGIDWVW.......
K9U9Q7_9CYAN/53-309                 ...............NNLK..NLQPEIL.RQNPSILP.TLRMCTCPPIARDRLIGLAGVAKSVVERME..VEGKLPVRLTGDRLDEQLRKITNIVSRLADRDIFTWLDTEQKPTESEIYRAATIVADRLCGSS.ADPIVRNAQEAR......QLREIAAWLNRRGYRLLPAD.RRVRFD.EM..LPGTYSFRLNIPVNl.ssEDGKT..VNIPVDAVIMRNTARRGDRPLLVEAKSAGDFTNVNKRRKEEARKIQQLQAT.YGN..TIEF.VLFLCGYFDSGYLGYEAA.EGIDWVW.......
E1T7P5_BURSG/88-319                 ...igaarsilldde----..-------.------LSdALRYLSGPPVSEDDLGVLVT---RSIGGIS..-KGAIK-RSES-----LALDILSLVRKLADPSRFPWIGQNRRPSFGEIR-TAVRSTTALQAS-.----QSLQTERRgy.gkvVERRLENRLVELGFARTPAP.HRALINdPI.dYPTYPNFYGECTV-....-HGRK..----VDLFIALPTGR----MIALEAKDSSSALNSVKRLNNDTAAKAKHFAVeGGK..NIIN.VALLSGVFKPEHLIRAQE.AGLHIVW.......
D0WLN5_9ACTO/59-290                 .....ltrlrdqahe----..-----L-.LTRHGYLT.EIRYLTSPSVSEDDLKVLTD------AKLS..-HSYLEKNPDA------TRNIIDVVLLGLDRERFPWLGENRMPTAEENT-AAIVSTAALIAN-.----QKVQTARRsaaknlQEDEVAKALLASGYVEVERR.SVDNFS.RI..-PGPGEFCKESLF-....--GGR..---KADLVIGLWDGR----AMPTECKVSNSSTNSVKRLNNDAAVKAKVWLReFGT..ASCIpAAVLSGVFKVHNLLSAQK.NDLTIFW.......
A1BGJ7_CHLPD/15-270                 ..............g-NMT..AVTPAVI.CDHPDILP.TLRMSTCPPLAVDRLIGLSGVSSNLVKSLE..LRKKLPSKMNSGLLDEDLHRIAAIIVKMADPDIFVWLGRKTQPDNDEIHRAATIVADRLCGAV.ANPIIRNAQEKR......QLAAIKSWLEARGYRQLQNG.EAVRFD.SM..PPGTFTFRMNVPVD...lEGGVK.rVNIPVDAVVMPGKSKKGALPVFFEAKSTGDFTNTNKRRKEEAMKMSQLRST.YGR..NVRF.NLFLCGYFDSGYLGYEAA.EGIDWVW.......
K9T9V4_9CYAN/53-309                 ...............NNLK..TLHPEIL.RQNPGILP.TLRMCTCPPIARDRLIGLANVAKSVVDCME..VLGKLPVRLTEARLDEELRKITDIVARLADRDIFPWLDSNQTPLESEIYRAATIVADRLCGSS.ADPIVRNAQEAR......QLREIAAWLDSRGYRLLPAS.QRVKFD.EM..PPGTYSFRLNIPVNl.aeEGGKT..VNIPVDAVIMRKAAQPGDRPLLVEAKSAGDFTNVNKRRKEEARKVQQLNAT.YGN..TIEF.VLFLCGYFDSGYLGYEAA.EGIDWVW.......
L7LQC5_9ACTN/57-290                 dltllkehavdllvr----..-------.---SEMRT.AIRFLASPWISEDDLKVLAN------TTLS..-AQRLRAEDGA-----GAQRVIDTILMGLDRSRFPWVSEDREPTQTERE-VAVISTAALIAT-.----QKMQTARRneskneQEELVTDYLIGQDWTQVPTR.T---IS.TLndAPAPGEFCRESKF-....--GTR..---KADLIVRLQDGR----VMPIECKVSNSFTNSVKRLNNDAAVKAKAWIAeFGT..LGAVpTAVIAGVFKVHNLKAAQD.DGLTILW.......
U5QC54_9CYAN/53-306                 ...............ENLT..DIKPSTI.RNSPAILP.TLRMSTCPPLAVDRLIGLARVSPGLVKTME..QGKRLPPQMNVAQADTELARVADVIERLADPDIFVWIGRPAPATTQEIHRAAIIVADRLCGAV.TNPIIRNAQEAR......QLAAIKAWLEARGYTPAPNG.I--RFN.TM..QPGTFSFRMNVPVT....QSGRVqsINIPIDAVIMPRTAAPGSLPIFFEAKSAGDFTNTNKRRKEEAVKMAQLRTT.HGL..GVQF.NLFLCGYFDSGYLGYEAA.EGIDWVW.......
A0A0D5LT20_9RHIZ/61-291             ....vdasviadlmr----..-------.--NDDSRR.AFCYLTAPPISEDDLKTLVE------ASIA..-PTRLEEHPDS------AEKLRGIIFRILDPHRFPWVKEGRDPDPHERS-AAIIASAALVSAKkVETFRRNDAKDR......QEEKVKELLRSLGYTEIPKR.DIL-NA.SA..APAVGEFMGETPL-....-AGAK..----ADVVATVPSGR----IMAIECKVSNSKVNSYKRIVHDTGGKATIWHDqLGR..ANVLaSAVLSGVFSVSNCETVQNdKGVYLFW.......
E5AMB6_BURRH/54-290                 .............sd--LNpgAITDDNLaEAYNLGLGeALRYLAGPPISDDDLQVIAD-----VDSIA..-PGVLKKNPEA------LRKVFKVIERVIDLHRFPWIEAGGAPTEQQRE-AALLASSVLLAA-.----QRIATERRnegkenQETKVKDYLRSLGFTEAPAV.A---IN.TIvkGPQAMQFCAECQL-....--GER..---KADVVVRLHDTR----LMAIECKVSNSATNSVKRLNNDAAVKAEYWIKqFGI..AQVVpAAALAGVFKVLNLEQAQA.RGLSLFW.......
E4NPA7_HALBP/50-271                 ..............n-NFR..DIEKEDI.REDPRIVR.ILRYLVKPKISQMKFGQFAGVNS--TNNYE..-EYTLAEASTP--NHQIAQDLADFTAANLDPEKVPWLSDPTIDEEEEIEYSRRWICDKIAEQE.ATTHYRNWRKDK......QEQTVAEMLDDAGYTDSGYSgKISSTN.DI..PVGT--YAEESKV-....-AGAD..V-QKADFIVRPTEDT----VIFIEAKAIGVRVDSHKRVKEIRNKASDWKDE.FEG..AET-.------------------.-------vaviegw
J1GS95_9ACTO/55-288                 ..........vdltr--LS..NLAVELL.-TNPQRLT.AIRYLASPAISEDDLKVLAD------AALT..-PKRLNADPDM------ARRVIETVLMGLDRERFPWVAESREPTESERA-TAVVSTAALIAT-.----QKVQTGRRneakktQEGAVADALRAAGFTEAPTR.AVT---.NMshLPAHGEFCAEALF-....--GSR..---KADLIVRLWDGR----VMPTECKVSNSSTNSVKRLNNDAAVKARTWIQeFGT..VTCVpAAVLSGVFKTHNLTSAQA.DGLTLFW.......
A0A073CCG9_PLAAG/62-317             ..............a-NIT..NITPAIL.QQYPSVLP.ILRMATAPPIARDRLIGLAGVSSNLVKNME..EKERIPPRIDRGTLDTELAKIGKIIARLVDKDIFSWLDTGRQPTDTEVHRAAIIIADRLCGAI.SDPIIRNAQERR......QLATIRQWLEQHGYSYIGGG.TRLSFE.RM..LPGTFSFRLNIPIL...lQGGTK.qINIPIDIVIKPIQSSPSQLPLLIEAKSAGDYTNPNKRRKEEAVKMAQLRNN.YGE..NVRF.ILFLCGYFDSGYLGYEAA.EGIDWVW.......
U1YI14_9BURK/53-311                 ...............ENLT..NIRPEIL.RKWPGVLP.TLRMSTCPPLAVDRLIGLAGVSSSMVKRME..KEKQLPVRMAAANIDHELVKIAAVIERLADPDIFVWIKRSDPATEAEIHRAATIVADRLCGSV.ANPIIRNAQEQR......QLAYIGQWLEARGYTKLPDR.SNVTFD.TM..PPGTYSFRMNVPVAk..gVGGDE.sINIPVDAVVMRKTAAKGDYPLLIEAKSAGDFTNTNKRRKEEAQKVNQLRAT.YGHirPIEF.ILFLCGYFDSGYLGYEAA.EGIDWVW.......
D4JUQ2_9FIRM/53-309                 ...............NYLN..NVSPAIL.IEHPEVLP.ILRMSTCPPIARDRLVGLAGVSKSLVQNMEdsENPHISPRMQRAKLIEELQSISDIIIKMADPDIFTWLSERRNPDETEIMRSSTIVADRLCGAV.ADPIIRNAQEKR......QLAAITTLLESKGYTLAESG.V--HYD.EM..KPGSFSFHTNVPVYv.agEQGDQ..VNIPVDVAILPLTANTGDMPLLLEAKSAGDFTNVNKRRKEEAVKMQQLRNT.YGV..DVSY.SLFLCGYFDSGYLGYEAA.EGIDWIW.......
#=GC seq_cons                       ..............t..lp..sltsthl..ppsthLs.tLRhhssPPlucDcLhsLAs.....lpshE...pt+Lss+.ss..hpttLp+IsclItRlhD.-lFsWLspsppPo-sEhphAAsIlADRLsuu..ssPllRNAQEcR......Q.stlpsaLcspGYsplsss.shhths.sM...PGohpFphps.l......tGsc..l...lDlVlh.hsup....slhlEAKuuGsaTNosKRhKE-AsKhuplpts.aGs..ssph.shhLsGhFcssaLshttA.-GlchlW.......
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