GenomeNet

Database: Pfam
Entry: RMP
LinkDB: RMP
Original site: RMP 
#=GF ID   RMP
#=GF AC   PF14996.1
#=GF DE   Retinal Maintenance
#=GF AU   Coggill P, Hetherington K
#=GF SE   Jackhmmer:Q96NL8
#=GF GA   27.00 27.00;
#=GF TC   27.70 27.70;
#=GF NC   23.10 23.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22177090
#=GF RT   Mutations in C8orf37, encoding a ciliary protein, are associated
#=GF RT   with autosomal-recessive retinal dystrophies with early macular
#=GF RT   involvement.
#=GF RA   Estrada-Cuzcano A, Neveling K, Kohl S, Banin E, Rotenstreich Y,
#=GF RA   Sharon D, Falik-Zaccai TC, Hipp S, Roepman R, Wissinger B,
#=GF RA   Letteboer SJ, Mans DA, Blokland EA, Kwint MP, Gijsen SJ, van
#=GF RA   Huet RA, Collin RW, Scheffer H, Veltman JA, Zrenner E, den
#=GF RA   Hollander AI, Klevering BJ, Cremers FP;
#=GF RL   Am J Hum Genet. 2012;90:102-109.
#=GF CC   RMP is encoded for by a gene, C8orf37. Mutations in the gene
#=GF CC   cause two types of retinal dystrophies: cone-rod dystrophy type
#=GF CC   16 (CORD16) and retinitis pigmentosa type 64 (RP64). CORD16
#=GF CC   affects the cone receptors which detect red, green or blue
#=GF CC   wavelengths of light and RP64 affects the cone receptors first
#=GF CC   and then the rod receptors. Both of these affect the
#=GF CC   photo-receptors in the eye leading to colour blindness or
#=GF CC   blindness respectively [1].
#=GF SQ   77
#=GS G3Q0Q9_GASAC/61-207   AC G3Q0Q9.1
#=GS G3VLR7_SARHA/70-213   AC G3VLR7.1
#=GS F4Y588_HUMAN/63-207   AC F4Y588.1
#=GS B3RIN7_TRIAD/57-204   AC B3RIN7.1
#=GS H0WVV6_OTOGA/63-207   AC H0WVV6.1
#=GS Q4DSD7_TRYCC/161-277  AC Q4DSD7.1
#=GS D2UZA0_NAEGR/99-252   AC D2UZA0.1
#=GS H0VLD9_CAVPO/65-211   AC H0VLD9.1
#=GS G1NWH7_MYOLU/42-187   AC G1NWH7.1
#=GS H0ZNY8_TAEGU/1-104    AC H0ZNY8.1
#=GS G0TU39_TRYVI/144-278  AC G0TU39.1
#=GS F6UB70_HORSE/64-209   AC F6UB70.1
#=GS F1RY59_PIG/63-207     AC F1RY59.1
#=GS F1P3N5_CHICK/1-104    AC F1P3N5.1
#=GS H2SZY5_TAKRU/1-83     AC H2SZY5.1
#=GS C3YFQ9_BRAFL/53-195   AC C3YFQ9.1
#=GS F6QAP7_MONDO/57-202   AC F6QAP7.1
#=GS A8Y7Q4_9EUKA/113-226  AC A8Y7Q4.1
#=GS F1PMK6_CANFA/13-157   AC F1PMK6.1
#=GS G1QTN2_NOMLE/63-207   AC G1QTN2.1
#=GS CH037_BOVIN/63-207    AC E1BC52.1
#=GS D8THF8_VOLCA/1-140    AC D8THF8.1
#=GS C1E9Y7_MICSR/77-280   AC C1E9Y7.1
#=GS G5C4B2_HETGA/64-208   AC G5C4B2.1
#=GS F2U5I5_SALS5/119-218  AC F2U5I5.1
#=GS E9B592_LEIMU/171-313  AC E9B592.1
#=GS CH037_MOUSE/64-209    AC Q3UJP5.1
#=GS A0E4E2_PARTE/7-140    AC A0E4E2.1
#=GS CH037_HUMAN/63-207    AC Q96NL8.1
#=GS A4IA79_LEIIN/163-313  AC A4IA79.1
#=GS D2HVB4_AILME/63-207   AC D2HVB4.1
#=GS A9UU67_MONBE/156-235  AC A9UU67.1
#=GS E9HLA0_DAPPU/214-286  AC E9HLA0.1
#=GS G5A9W7_PHYSP/54-204   AC G5A9W7.1
#=GS B1AV75_MOUSE/64-210   AC B1AV75.1
#=GS H2ZFB3_CIOSA/1-97     AC H2ZFB3.1
#=GS E7LNU6_TRYCR/149-264  AC E7LNU6.1
#=GS Q23E95_TETTS/114-263  AC Q23E95.2
#=GS Q581R2_TRYB2/164-279  AC Q581R2.1
#=GS G3VLR8_SARHA/70-211   AC G3VLR8.1
#=GS G3UQI6_MELGA/66-210   AC G3UQI6.1
#=GS F7ELY2_ORNAN/1-48     AC F7ELY2.1
#=GS G1KX11_ANOCA/52-198   AC G1KX11.1
#=GS G7PC93_MACFA/63-207   AC G7PC93.1
#=GS C9ZM30_TRYB9/164-278  AC C9ZM30.1
#=GS F7I023_CALJA/63-207   AC F7I023.1
#=GS D0N9B8_PHYIT/56-206   AC D0N9B8.1
#=GS Q4S482_TETNG/60-142   AC Q4S482.1
#=GS E4X424_OIKDI/50-190   AC E4X424.1
#=GS G3SS75_LOXAF/59-203   AC G3SS75.1
#=GS F6QMY3_MONDO/43-184   AC F6QMY3.1
#=GS F7G484_MACMU/63-207   AC F7G484.1
#=GS G9L4X2_MUSPF/1-126    AC G9L4X2.1
#=GS G7YPV7_CLOSI/2-118    AC G7YPV7.1
#=GS A8J6H2_CHLRE/89-254   AC A8J6H2.1
#=GS A2EVS0_TRIVA/14-156   AC A2EVS0.1
#=GS H3HD94_PHYRM/318-471  AC H3HD94.1
#=GS G3MNW2_9ACAR/28-195   AC G3MNW2.1
#=GS F0VZV9_9STRA/44-200   AC F0VZV9.1
#=GS G1NHP4_MELGA/64-208   AC G1NHP4.2
#=GS A7RHF6_NEMVE/52-194   AC A7RHF6.1
#=GS H0ZUB4_TAEGU/1-83     AC H0ZUB4.1
#=GS G3QXT9_GORGO/63-207   AC G3QXT9.1
#=GS A4HB22_LEIBR/160-314  AC A4HB22.1
#=GS Q4Q2P1_LEIMA/170-313  AC Q4Q2P1.1
#=GS CH037_RAT/65-210      AC Q6AY71.1
#=GS G1SEN4_RABIT/63-207   AC G1SEN4.1
#=GS H2PQU8_PONAB/63-207   AC H2PQU8.1
#=GS A2DWY6_TRIVA/59-213   AC A2DWY6.1
#=GS H2MKU7_ORYLA/64-210   AC H2MKU7.1
#=GS G1KCI3_ANOCA/64-212   AC G1KCI3.1
#=GS H2QWG3_PANTR/63-207   AC H2QWG3.1
#=GS C1MI95_MICPC/83-248   AC C1MI95.1
#=GS H2MKU8_ORYLA/70-216   AC H2MKU8.1
#=GS A0DZL1_PARTE/10-140   AC A0DZL1.1
#=GS D8LN08_ECTSI/147-298  AC D8LN08.1
#=GS E9BR84_LEIDB/163-313  AC E9BR84.1
G3Q0Q9_GASAC/61-207              .........................................................i-DVLLEE..........LLAEDFPQLKREAFPEGPQ.VETKPSAQSGGR..N..................................SSRCCPV.FVGGSAVASGVGTATSK........RSCDQLRCTSCDFRVLTFDDRAWDP........S...CD.YLFL.RrNNVPDREKLGA.......R...............LRRSGGSRAFACQCSWFSA.....DEPTDLREQ...PRLRWVCGKH...............
G3VLR7_SARHA/70-213              ..........................................................LDGLINE..........IFEEPCFDKKPIVQNLKSK.SSNHTSVRTSIQ.vL..................................GKRCSPV.YIGGSSTPCGIGTNTSQ........RTCDQLRCTACDFRVLNFDDYIWDK........S...CD.YLFF.R.NNMPEFNKLKA.......K...............MTKRKGTRAYACQCSWRNV.....EELTDLQTD...QQLRWC----p..............
F4Y588_HUMAN/63-207              ..........................................................LDSLINE..........ILEEPNLDKKPS-KLKSKS.SGNTSVRASIEG..L..................................GKSCSPV.YLGGSSIPCGIGTNISW........RACDHLRCIACDFLVVSYDDYMWDK........S...CD.YLFF.R.NNMPEFHKLKA.......K...............LIKKKGTRAYACQCSWRTI.....EEVTDLQTD...HQLRWVCGKH...............
B3RIN7_TRIAD/57-204              ..........................................................LSRMIED..........ICSVEDESDIEKRRREVNK.IAEKKSVTKQQSldC..................................SKRCYQV.YLGGSKSLIGLATISSQ........RACNQLRCTACDFRVSYYDDYEWHQ........R...SN.YIFF.R.NNMPDFEKIRV.......N...............LLRKLGTRAYACQCSWKSI.....ADVVPVDNY...TDLKWVCGRH...............
H0WVV6_OTOGA/63-207              ..........................................................LDNLINE..........IFEEPNFDKKPC-KLKSKS.SGNTSVKASIQA..F..................................GKSCSPV.YLGGSAIPCGIGTNTSW........RACDHLRCVACDFCIVSYNDYMWDK........S...CD.YLFF.R.NNMPEFHKLKA.......K...............LIKKKGSRAYACQCSWRTI.....EELTDLQTD...HQLRWVCGKH...............
Q4DSD7_TRYCC/161-277             .......................................dakfgngasdryaenmgcs-------..........-------------------.------------..-..................................-------.-----------------........GGCPVMVCRKCNYGVIRLQGAAWNDg.....egR...IDlYLTV.R.NYYPDWSRLANsfpvgkaKgae........ndrvLGPSVGCAAYCCQCSWLTV.....KSAQEIIE-...----------trlshtvg.......
D2UZA0_NAEGR/99-252              ..........................................................LDDFMNE..........LIEDSPTSPIIKRKNSIPK.NASVGAFTTSSP..Vsslt..........................sprvSKKCSTT.YLSNRHDSFGINTFLTP........KRCSDLRCMKCDFKVINFDGKKWKE........D...VN.YLFF.R.NNYPETVKKGF.......E...............EKEFPDHTSYCCQCSWITV.....SDRTSAKNL...TSLNWYCGGH...............
H0VLD9_CAVPO/65-211              ..........................................................LDSLINE..........IFEEPSFDQKPLQKLKSKS.SGHTSVRASLQD..P..................................HKSCSPV.YLGGSTVLSGIGTHTSQ.......sRACDHLRCIACDFRVVSYNDYMWDK........S...CD.YLFF.R.NNMPEFHKLKT.......K...............LVKKKGTRAYACQCSWRTI.....EDLTDLQAD...HQLRWVCGKH...............
G1NWH7_MYOLU/42-187              ..........................................................LDSLINE..........IFEDPNFDKKSFQKLKPKS.SGNTSVSAPIQG..R..................................GKSCNPV.YLGGSTAPCGIGTTTSQ........RSCDHLRCTACDFWVVSYDDYMWDK........S...CD.YLFF.R.NNMPEFHKLKT.......K...............LVKKKGARAYACQCSWRTI.....VELTDLQTD...HQLRWVCGKH...............
H0ZNY8_TAEGU/1-104               ..........................................................-------..........-------------------.------------..-..................................---CCPV.YLGGSLSPSGIGTNISK........RTCDQLRCTACDFRVSLFNDYIWDQ........S...CD.YLFF.R.NNMPELSKLRA.......K...............MIKKKGARAYACQCSWRSI.....DELTDLQTE...QQLRWVCGKH...............
G0TU39_TRYVI/144-278             ...................nelssqqqlldrkgafhtsnpnagngavdkladetgfrg-------..........-------------------.------------..-..................................-------.-----------------........-GCPFLQCRKCNYVVIRLQGASWQDg.....dgK...LDlYLTV.R.NFYPDWSRLAS.......Sypvgipk.ssdrkkvLQPSSDCAAYCCQCSWLTV....kSEQEKVET-...----------hltdlt.........
F6UB70_HORSE/64-209              ..........................................................LDSLINE..........IFEEPNFDRKSFQKLKSKS.SGNTSVRASVPG..L..................................GKSCSPV.YLGGSAAPCGIGTNTSQ........RACDHLRCIACDFWIVSYDDYMWDK........S...CD.YLFF.R.NNMPEFHKLKT.......K...............LVKKKGTRAYACQCSWRTI.....EELTDLQTD...HQLRWVCGKH...............
F1RY59_PIG/63-207                ..........................................................LDSLINE..........IFEKPNFDKKHFK-LKSTS.SGNASVRAPTQG..L..................................GKSCSPV.YLGGSAVPCGIGTNTSQ........RACDHLRCIACDFWIVSYDDHRWDT........S...CD.YLFF.R.NNMPEFHKLKT.......K...............LVKKKGTRAYACQCSWRTI.....EALTDLQND...HQLRWVCGKH...............
F1P3N5_CHICK/1-104               ..........................................................-------..........-------------------.------------..-..................................---CCPV.YLGGSSSPNGIGTNISK........RTCDQLRCTACDFCVSLFNDYIWDQ........S...CD.YLFF.R.NNMPELSKLRA.......K...............MIKKKGSRAYACQCSWRSI.....DELTDLQAD...QQLRWVCGKH...............
H2SZY5_TAKRU/1-83                ..........................................................-------..........-------------------.------------..-..................................-------.-----------------........RSCDQLRCTSCDFRVLMFDDCEWDS........S...CD.YLFL.R.NNTPDGHKLRA.......R...............LNRRRGVRAYACQCSWFSV.....LEPTDLREL...PQLMWVCSKH...............
C3YFQ9_BRAFL/53-195              ..........................................................LDAMIDD..........ICEAPEPLEPLVDKAPAQN.SPRTPRGAEG--..-..................................KRRCAVL.YLGGSKHAMGLGSSMNQ........RSCDQLRCTDCDFRVVFYDNYEWDA........S...CE.YLFF.R.NNVPDFGKLKA.......K...............LNKRKGSRAYACQCKWTSV.....QDLVDIQKK...TDFKWVCGKH...............
F6QAP7_MONDO/57-202              ..........................................................LDGLINE..........IFEEPCFHRNPV-KLKSKS.SNNTSVRTSIQM..L..................................GKRCSPV.YLGGSSAPCGIGTNTSQ.......sRTCDQLRCTACDFRVLSFDDYMWDK........S...CD.YLFF.R.NNMPEFSKLKA.......K...............MIKQKGTRAYACQCSWRDI.....KELTDLRTD...QQLRWVCGKH...............
A8Y7Q4_9EUKA/113-226             ..............................dtaaldaplstpvkgdsgfrkctvvmlg-------..........-------------------.------------..-..................................-------.----------------Qt......pAACSNLRCTMCDHAVVRIVKREWDP........S...CD.YFFF.R.NNVPDLTKLGR.......K...............LRDAPRSTAYACQCSWTTA.....TNTVAITSS...SPHKWVCAGH...............
F1PMK6_CANFA/13-157              ..........................................................LDSLINE..........IFEEPNLDKKPV-KLKSKS.SGNPSVRASTQS..L..................................GKSCSPV.YLGGSTAPCGIGTNTSQ........RACDRLRCVACDFRVVSYDDYMWDH........S...CD.YLFF.R.NNMPEFQKLRT.......K...............LVKKPGARAYACQCSWRTA.....EALTALQAD...PQLRWVCGRH...............
G1QTN2_NOMLE/63-207              ..........................................................LDSLINE..........IFEEPNLDKKPS-KLKSKS.SGNTSVRASIQG..L..................................GKSCSPV.YLGGSSIPCGIGTNISW........RACDHLRCIACDFLVVSYDDCMWDE........S...CD.YLFF.R.NNMPEFHKLKA.......K...............LIKKKGTRAYACQCSWRTI.....EEVTDLQTD...HQLRWVCGKH...............
CH037_BOVIN/63-207               ..........................................................LDSLINE..........IFEEPHFDKKHF-KLKSKS.SGNTSVRASIQG..L..................................GKSCSPV.YIGGSTVPCGIGTNASP........RACDHLRCTACDFWVESYDDYRWDK........S...CD.YLFF.R.NNMPEFHKLKT.......K...............LVKKKGTRAYACQCSWKAV.....EELTDLQTD...HQLRWVCGKH...............
D8THF8_VOLCA/1-140               .......................................................mng-------..........---RNNPRAVAAAEAAVQK.LAGPSRKSSVIG..S..................................KQKCTGV.FIGGTSFVRGRMGAVGS.......lTCCDALRCTKCDFRVEQFHNRDWSD........D...VD.YLFF.R.NNFPTEAKLAA.......K...............MRARPGSVAYCCQCSWMST.....VEESKLDFS...SDVRWVCAGH...............
C1E9Y7_MICSR/77-280              .....................................lddllgeldavmgsgvsplte-------..........---RPKPASSSATTTTSQK.SNAPSSSSSSAP..RvaafdpsrvrtgdpsdprggahlapnprgggtggGARCAPCaIVGGSDAKLGRASFMSP.......dAPCDALRCVSCDFDVVSFDGVAWCSgeggvkgpG...VD.YMFF.R.NNYPDASAMGA.......R...............ATERTGWRAYCCQCSWRSLg...vGGREKVDGV..gGELRWVCGGH...............
G5C4B2_HETGA/64-208              ..........................................................LDSLINE..........IFEEPNFDKKPFKLK-SKS.SGDTSVRASLQV..S..................................HKSCSPV.YLGGSTVPYGIGTHTSQ........RACDHLRCIACDFRVVSYSDYLWDK........S...CD.YLFF.R.NNMPEFHRLKI.......K...............LVEKKGTRAYACQCSWRTV.....EELMDLQTD...HRLRWVCGKH...............
F2U5I5_SALS5/119-218             ...........................vdtllmdlessvparapahrvssrppaials-------..........-------------------.---TTSAQGSSS..Slnd............................ngrPTKCAHI.VLTDAGQPRGIATSSQA........CTCSTLRCTSCDHSVCCFDSVRWDD........K...V-.----.-.-----------.......-...............-------------------.....---------...----------lh.............
E9B592_LEIMU/171-313             ...........qlraiavneqanldtsriqamlrkgafhaaiaklgngcldhhgdftv-------..........-------------------.------------..-..................................-------.----------------D........GGCPNILCRQCNYMVVRLQGAEWDD........D..gVNlYLTL.R.NYYPDWCRLAS.......AtpvgvedgaeasrsvLRSSLAAAAYCCQCSWVTV.....RSIKAV---...----------ietrltdi.......
CH037_MOUSE/64-209               ..........................................................LDSLINE..........IFEEPDFDRKSFQKFKSKS.SSNTCVRAPMQG..V..................................SKSCSPV.YLSGSAIPCGIGTNTSQ........RACDRLRCVACDFRIVSYNDYMWDK........S...CD.YLFF.R.NNMPEFHKLKT.......K...............LIEKKGARAYACQCSWRTV.....EELTDLQTD...HQLRWVCGKH...............
A0E4E2_PARTE/7-140               .......................................................dddLDDLIND..........INSVMDNPQSKPISQQNYQ.PQPQPNQGQQ--..Q..................................KRKCLSP.QIGNQA---------QY........RICTNLRCLKCDLQVQCHINQKWNK........D...AD.YLIF.R.NYFNNMSILCK.......Y...............LTQDNQCNAYNCQCTSAN-.....-ALESIAA-...-PQNWVCSGH...............
CH037_HUMAN/63-207               ..........................................................LDSLINE..........ILEEPNLDKKPS-KLKSKS.SGNTSVRASIEG..L..................................GKSCSPV.YLGGSSIPCGIGTNISW........RACDHLRCIACDFLVVSYDDYMWDK........S...CD.YLFF.R.NNMPEFHKLKA.......K...............LIKKKGTRAYACQCSWRTI.....EEVTDLQTD...HQLRWVCGKH...............
A4IA79_LEIIN/163-313             ....daghptlqqlraiaaneqasldtsriqamlrkgafhaaiaklgngcldhhgdft-------..........-------------------.------------..-..................................-------.---------------VD........GGCPNILCRQCNYMVVRLQGAEWDD........D..gVNlYLTL.R.NYYPDWCRLAS.......AtpvgvedgaeasrgvLRSSSAAAAYCCQCSWVTV.....RSAKM----...----------vietrltdi......
D2HVB4_AILME/63-207              ..........................................................LDSLINE..........IFEEPTFDKKPF-KLKSKS.SGNTSVRASIQG..L..................................GKSCSPV.YLGGSTAPCGIGTNTSQ........RACDHLRCIACDFWVVSYDDHMWDK........S...CD.YLFF.R.NNMPEFHKLRT.......K...............LVKKKGTRAYACQCSWRTV.....EDLTDLQTD...QQLRWVCGKH...............
A9UU67_MONBE/156-235             ................................lecanrivaapclfklmmimawclpi-------..........-------------------.------------..-..................................-------.----------------S........RACDRARCTKCDHAVLHFEDARWQS........D...CE.VLFF.R.NYVPNRVKLST.......K...............IDA----------------.....---------...----------lpvta..........
E9HLA0_DAPPU/214-286             ......................................................nsqs-------..........-------------------.------------..-..................................-------.-----------------........-----------------VRHYRWRP........G...TD.YLFL.R.NHMPEFDRVRV.......K...............LSTAKFCRAYACQCKFVTV.....KDLVDLTKLgpeFASTWICLGH...............
G5A9W7_PHYSP/54-204              ..........................................................LDDLLDM.........lGDEDSKPAAVHPRPMSTTR.AGAYNSSETKTT..-..................................RTECPQA.LMDGGRATRGLSTAFSRkyv..tvfIVCSNLRCNECDFTVVQFPGKKWDA........S...AD.YMFF.R.ENVPSEVKLRA.......K...............MEIAPEFAAYACQCKWLSI.....SSQTRVDH-...CQVKWSCAGH...............
B1AV75_MOUSE/64-210              ..........................................................LDSLINE..........IFEEPDFDRKSFQKFKSKS.SSNTCVRAPMQG..V..................................SKSCSPV.YLSGSAIPCGIGTNTSQ........RACDRLRCVACDFRIVSYNDYMWDK........S...CD.YLFFsR.NNMPEFHKLKT.......K...............LIEKKGARAYACQCSWRTV.....EELTDLQTD...HQLRWVCGKH...............
H2ZFB3_CIOSA/1-97                .............................................mkntrtpkipvdk-------..........-------------------.RKCSTILLSSGS..K..................................TKKCSAI.YLGGSTTTRGLCSVSVK........RCCDQLRCTNCDFHVEQYNNYKWDN........T...VD.YLFL.R.NNMPDFQKVAS.......K...............L------------------.....---------...----------i..............
E7LNU6_TRYCR/149-264             .......................................akfgngasdryaenmgcsg-------..........-------------------.------------..-..................................-------.-----------------........-GCPVMVCRKCNYGVIRLQGAAWNDg.....egR...IDlYLTV.R.NYYPDWSRLANscpvgkaKgae........ndrvLGPSVGCAAYCCQCSWLTV.....KSAQEIIE-...----------trlshtvg.......
Q23E95_TETTS/114-263             ..........................................................IDDLLD-..........ILNQEDYKVQKGQTKVAQQ.DISQPIKQSDAP..Kan..............................qkLTTCLNPyLCNGNSDYASDEFNMRK........RVCNALRCSLCNIMITKLVDYKWAQ........D...AD.LLFF.R.NNFSRKEKLIT.......K...............AISDSSYSAYSCQCRGTSV.....NKLTTLAEC...NMKEWRCTGH...............
Q581R2_TRYB2/164-279             .........................................agngctdktadedgrkg-------..........-------------------.------------..-..................................-------.-----------------........-GCPFILCRKCNYTVIRLQDAEWDD........EegkMDlYLTV.R.NFYPDWSRLAS.......Slpvgqmr.rgeqntvLKTCPDSAAYCCQCSWLTV....kCAQEVID--...----------trvtdhtkfv.....
G3VLR8_SARHA/70-211              ..........................................................LDGLINE..........IFEEPCFDKK-PINLKSKS.SNHTSVRTSIQV..L..................................GKRCSPV.YIGGSSTPCGIGTNTSQ........RTCDQLRCTACDFRVLNFDDYIWDK........S...CD.YLFF.R.NNMPEFNKLKA.......K...............MTKRKGTRAYACQCSWRNV.....EELTDLQTD...QQLRWC----p..............
G3UQI6_MELGA/66-210              ..........................................................IDDIIDE..........ICNDSSFARTPLKLKSNYP.SVRPGSSSAVVQ.aH..................................RKRCCPV.YLGGSSSPNGIGTNISK........RTCDQLRCTACDFRVSLFNDYIWDQ........S...CD.YLFF.R.NNMPELNKLRA.......K...............MIKKKGSRAYACQCSWRSI.....SELTDLQAD...QQLRY-----ifs............
F7ELY2_ORNAN/1-48                ..........................................................-------..........-------------------.------------..-..................................-------.-----------------........-------------------------........-...--.----.-.--MPELGKLKA.......R...............LVKKKGTRAYACQCSWRSV.....EELIDLQTA...QRLHWVCGQH...............
G1KX11_ANOCA/52-198              ..........................................................LDDIIKD.........iIDEKSSAQSLVKQTSELSS.PASRNNITSVQA..H..................................GKRCCPV.YLGGSTAPYGIGTSISQ........RTCDRLRCTACDFRVSHYDDYQWDK........S...CD.YLFF.R.NNMPEFSKLRA.......K...............MLKKKGSRAYACQCAWRSI.....DGLTDLSTD...RQLRWVCSEH...............
G7PC93_MACFA/63-207              ..........................................................LDSLINE..........IFEEPNLDKKPS-KLKSKS.SGNTSVRASIQG..L..................................GKSCSPV.YLGGSSIPCGIGTNISW........RACDHLRCIACDFLVVSYDDYMWDK........S...CD.YLFF.R.NNMPEFHKLKA.......K...............LVKKKGTRAYACQCSWRTI.....EEVTDLQTD...HQLRWVCGKH...............
C9ZM30_TRYB9/164-278             .........................................agngctdktadedgrkg-------..........-------------------.------------..-..................................-------.-----------------........-GCPFILCRKCNYTVIRLQDAEWDD........EegkMDlYLTV.R.NFYPDWSRLAS.......Slpvgqmr.rgeqntvLKTCPDSAAYCCQCSWLTV.....KSAQEV---...----------idtrvtdhtkf....
F7I023_CALJA/63-207              ..........................................................LDSLINE..........IFEEPNLDKKPS-KLKSKS.SGNTSVRASIQG..L..................................GKSCSPV.YLGGSSIPCGIGTSISW........RACDHLRCIACDFLVVSYDDYMWDK........S...CD.YLFF.R.NNIPEFHKLKA.......K...............LIKKKGTRAYACQCSWRTI.....EELTDLQTD...RQLRWVCGKH...............
D0N9B8_PHYIT/56-206              ..........................................................LDDLLDM.........lGDEDSKPTAVHPRPKSSSR.AGAYNSPDSKIS..-..................................RTECPQV.LLDGGHASRGLSTAFSSrha..ysfSSCSNLRCNECDFTVVQFPGKKWDA........S...VD.YMFF.R.ENVPSEAKLRV.......K...............MEIAPDFTAYACQCKWLSI.....CSQTRMDN-...CQVKWSCAGH...............
Q4S482_TETNG/60-142              ..........................................................IDAFLEE..........LLDAKDDGCQQLKTK--SE.GCSEEKKTSSSA..G..................................QRKCCPV.FLGGSSVMNGVGTVTSK........RSCDQLR------------------........-...--.----.-.-----------.......-...............-------------------.....---------...----------aplatsvccclrtvs
E4X424_OIKDI/50-190              ..........................................................IDDFLKE..........FSDDDNEDWKSSSKVNSFK.KNKESSASA---..-..................................TKKCSPF.VYISASDPEGLTKPSQV........MSCDRLRCFSCDFDVVGFRGYRWTS........D...TD.YLFL.R.NNHPLKEKLKA.......N...............LVVDPSSSAFCCQCESISI.....SKRTKLDS-...TSLSWSCRSH...............
G3SS75_LOXAF/59-203              ..........................................................LDSLINE..........IFEEPNFDKKPF-KLKSKS.SGNTSVKASIQG..L..................................GKSCSPV.YLGGSTAPRGIGTNISQ........RACDHLRCIACDFWIVSYDDYMWDK........S...CN.YLFF.R.NNMPEFHKLKT.......K...............LVKKAGARAYACQCSWRTV.....EELTDLQTD...HQLRWVCGKH...............
F6QMY3_MONDO/43-184              ..........................................................LDGLINE..........IFEEPCFHRNPV-KLKSKS.SNNTSVRTSIQM..L..................................GKRCSPV.YLGGSSAPCGIGTNTAQ........KTCDQLRCTACDFC---FDDYMWDK........S...CD.YLFF.R.NNMPEFSKLRA.......K...............MIKQKGTRAYACQCSWRDI.....KELTDLRTD...QQLRWVCGKH...............
F7G484_MACMU/63-207              ..........................................................LDSLINE..........IFEEPNLDKKPS-KLKSKS.SGNTSVRASIQG..L..................................GKSCSPV.YLGGSSIPCGIGTNISW........RACDHLRCIACDFLVVSYDDYMWDK........S...CD.YLFF.R.NNMPEFHKLKA.......K...............LVKKKGTRAYACQCSWRTI.....EEVTDLQTD...HQLRWVCGKH...............
G9L4X2_MUSPF/1-126               ........................................................ks-------..........-----------------KS.SGNTSVRASIQG..L..................................GKSCSPV.YLGGTAAPCGIGTNTSQ........RACDHLRCIACDFWVVSYDDYMWDK........S...CD.YLFF.R.NNMPEFHKLKT.......K...............LVKKKGTRAYACQCSWRSIedlsiEDLTDLQTD...QQLRWVC---...............
G7YPV7_CLOSI/2-118               .....................................................sichr-------..........-------------------.------------..-..................................---CSVP.CIAGVEMSLGWNKYKVHitdqpmtsRACNTLRCIACDNAVVIFDNSSWSS........D...VD.YYFL.R.TNYPNTKRLQA.......K...............MKRKGGSRAYCCQCSSTEA.....TKLTCLDGI...PSLQWVCGKH...............
A8J6H2_CHLRE/89-254              ........................................................ld--NLLGEldfggtpynsMNGRQGASALGTVTAAAAK.LSSTTSTGTPPP.pSrgss..........................viasKQKCTGV.FTGGTSFPRGRMGAVGA.......lTCCDALRCTKCDFRVEQFNNREWHA........D...VD.YLFF.R.NNFPNEEKLAP.......K...............MRSRQGSVAYCCQCSWLNS.....TEQAKLDFS...SELRWVCAGH...............
A2EVS0_TRIVA/14-156              .........................................qldrelgplsipsptks-------..........----------HSKSSLNRS.ANSAMRHSP---..Si................................pSLKCAVA.CIGGPDLPSGRTSDVTT.......pHFCSNLICVSCDHKVIRFPNYKWSP........N...TD.YLFL.R.NNYPD--TVEQ.......N...............LIPAPGRCAYCCQCTFCDE.....TDVKHLNS-...FNSTWACRGH...............
H3HD94_PHYRM/318-471             ..........................................................LDDLLDM.........lGDDDSKPAAIHPRPMSSSR.AGAYNSSDSKTS..Rtef...........................qaggTKKCPQV.LMDGGRATRGLSTAFSS.......rNVCSNLRCNECDFTVVQFPGKKWDA........S...AD.YMFF.R.ENVPNEAKLRV.......K...............MEISPEFAAYACQCKWLSV.....SSQIRVDN-...CQVKWSCAGH...............
G3MNW2_9ACAR/28-195              ........ldillddveakfckqvnravstsavkassddsiedaindickapehnvpn-------..........-------------------.--NVLTENKLFS.cR..................................TTQCFVV.YLAGTDVALGVSTSASK........RACSHVHCCRCDFQVAIFEDFAWDQ........S...AD.YLFF.R.NSTPDMNKLRS.......K...............LVWKLGWRAYCCQCQWRSV.....AALSSVQQ-...EKLPWTCAHH...............
F0VZV9_9STRA/44-200              ..........................................................IDDLLD-..........LVSSSGPMSLPTRNPVVHT.PFNRQGVDAIFP..Lpagr.........................cfasvNKKCARV.TLGGSRMKRGHSSAFMT.......sCVCSNLRCIDCDFTVIQFQDRIWNK........S...AD.YMFF.R.ENMPNERKLQA.......K...............LDEIFGFTAYACQCKWTSA....gSEPVSIENN..gTMARWTCAGH...............
G1NHP4_MELGA/64-208              ..........................................................IDDIIDE..........ICNDSSFARTPLKLKSNYP.SVRPGSSSAVVQ.aH..................................RKRCCPV.YLGGSSSPNGIGTNISK........RTCDQLRCTACDFRVSLFNDYIWDQ........S...CD.YLFF.R.NNMPELNKLRA.......K...............MIKKKGSRAYACQCSWRSI.....SELTDLQAD...QQLRY-----ifs............
A7RHF6_NEMVE/52-194              ..........................................................LSDIIRD..........ICEDDGPDLPPVVPPPTGS.PSSTPGLTAH--..-..................................KSKCFTL.LLGGTRFSKGLCTVSEQ........RTCDKLRCTSCDFKVVVFDNYAWDG........D...CD.YLFF.R.NNVPDFHKLKV.......K...............LKTRKGTRAYACQCCWRSI.....VDLMDLQTD...ATLKWVCGKH...............
H0ZUB4_TAEGU/1-83                ..........................................................-------..........-------------------.------------..-..................................-------.-----------------........RTCDQLRCTACDFRVSLFNDYIWDQ........S...CD.YLFF.R.NNMPELSKLRA.......K...............MIKKKGARAYACQCSWRSI.....DELTDLQTE...QQLRWVCGKH...............
G3QXT9_GORGO/63-207              ..........................................................LDSLINE..........IFEEPNLDKKPS-KLKSKS.SGNTSVRASIQG..L..................................GKSCSPV.YLGGSSIPCGIGTNISW........RACDHLRCIACDFLVVSYDDYMWDK........S...CD.YLFF.R.NNMPEFHKLKA.......K...............LIKKKGTRAYACQCSWRTI.....EEVTDLQTD...HQLRWVCGKH...............
A4HB22_LEIBR/160-314             fltsdtdhptlqelraiavdeqanagssriqamlrkgafhaakanlgngcldhhgdft-------..........-------------------.------------..-..................................-------.---------------VD........GGCPHILCRHCNYMVVRLQGAQWED........D..gVNlYLTL.R.NYYPDWCRLAS.......AtpvgvedgaeasrcvLRTSLPAAAYCCQCSWVTV.....RCAK-----...----------avvetrltdi.....
Q4Q2P1_LEIMA/170-313             ..........hqlraiaaneqasldtsriqamlrkgafhaaiaklgngcldhhgdftv-------..........-------------------.------------..-..................................-------.----------------D........GGCPNILCRQCNYMIVRLQGAEWAD........S..gVNlYLTL.R.NYYPDWCRLAS.......AtpvgveagaeatrsvLRSSSAAAAYCCQCSWVTV.....RSA------...----------kvfietrltdi....
CH037_RAT/65-210                 ..........................................................LDSLINE..........IFEEPNFDKKSFQKFKSKS.SSNTSVRAPIQG..L..................................SKSCSPV.YLSGSAIPCGIGTNTSQ........RACDRLRCVACDFQIVSYNDYMWDK........S...CD.YLFF.R.NNMPEFHKLKT.......K...............LIEKKGARAYACQCSWRTV.....EELTDLQAD...HELRWVCGKH...............
G1SEN4_RABIT/63-207              ..........................................................LDTLIKE..........IFEEPTFDKKPF-KVKSKS.SGNTSIRASIQG..L..................................GKSCSPV.YLGGSSVPCGIGTNISQ........RACDHLRCITCDFRVVSYNDCMWDK........S...CD.YLFF.R.NSMPDFHKLKT.......K...............LVKKKGTRAYACQCSWRTI.....EELTELHSD...HLLRWVCGKH...............
H2PQU8_PONAB/63-207              ..........................................................LDSLINE..........IFEEPNLDKKPS-KLKSKS.SGNTSVRASIQG..L..................................GKSCSPV.YLGGSSIPCGIGTNISW........RACDHLRCIACDFLVVSYDDYMWDK........S...CD.YLFF.R.NNMPEFHKLKA.......K...............LIKKKGTRAYACQCSWRTI.....EEVTDLQTD...HQLRWVCGKH...............
A2DWY6_TRIVA/59-213              .............................................mnfieelihstdl----DKE..........NITDENKEGQFQIDSYNHV.GLSPSPRSPVKStdA..................................SKHCADI.FIGPPSLLPGITISPLE.......pHFCKNLQCINCDHIVLRFPDRKWAS........N...VD.YLFL.R.NNYPN--KVDS.......R...............LVPSPGFCAFCCQCTFKDT.....DKLERLGH-...FDSDWVCRGH...............
H2MKU7_ORYLA/64-210              ..........................................................IDALLEE..........LLEDKDTYSPQSKSQQNRP.KETQVENKLSFQ.iG..................................RRKCCPV.FVGGSSVTNGVGTATSK........RSCDQLRCVSCDFRVVMFDDCEWDQ........S...CD.YLFL.R.NNMPDCQKLRK.......K...............LKKKRGQRAYACQCSWFSA.....SEPADLRDQ...PQLRWVCGKH...............
G1KCI3_ANOCA/64-212              ..........................................................LDDIIKD..........IIDEKMFSKKQTSELSSPAsRNNITSVQAHEVqgS..................................LKRCCPV.YLGGSTAPYGIGTSISQ........RTCDRLRCTACDFRVSHYDDYQWDK........S...CD.YLFF.R.NNMPEFSKLRA.......K...............MLKKKGSRAYACQCAWRSI.....DGLTDLSTD...RQLRWVCSEH...............
H2QWG3_PANTR/63-207              ..........................................................LDSLINE..........IFEEPNLDKKPS-KLKSKS.SGNTSVRASIEG..L..................................GKSCSPV.YLGGSSIPCGIGTNISW........RACDHLRCIACDFLVVSYDDYMWDK........S...CD.YLFF.R.NNMPEFHKLKA.......K...............LIKKKGTRAYACQCSWRTI.....EEVTDLQTD...HQLRWVCGKH...............
C1MI95_MICPC/83-248              ....................................................vddlla------Didgv..lgsgASTSARPPSGRPIPIAPRV.ADRGSERSAAVA..Vggg...........................gragGVRCAPCpSIAGARLPLGGPSSHFD.......aKACDAMRCTGCDFDVLSFERAAWRD........G...VD.YMFF.R.NAYPDAGKLSA.......A...............TATRRGGRAYCCQCSWRSAr...eEDVEEIKAM..sGTLRWVCGGH...............
H2MKU8_ORYLA/70-216              ..........................................................IDALLEE..........LLEDKDTYSPQSKSQQNRP.KETQVENKLSFQ.iG..................................RRKCCPV.FVGGSSVTNGVGTATSK........RSCDQLRCVSCDFRVVMFDDCEWDQ........S...CD.YLFL.R.NNMPDCQKLRK.......K...............LKKKRGQRAYACQCSWFSA.....SEPADLRDQ...PQLRWVCGKH...............
A0DZL1_PARTE/10-140              ..........................................................LDDLIND..........INSVMDNPKSKPVSQQNYQ.LEQQPNQSQQ--..Q..................................KRKCLSP.QIGNQQ---------QF........RTCTNLRCLKCDLQVKCHINQKWNK........D...AD.YLIF.R.NYFNNMAILQK.......Y...............LTEDNQCNAYNCQCTN--I.....NALESIDA-...-PQNWVCSGH...............
D8LN08_ECTSI/147-298             .....................ptiteiaseqtaatimvtpstmpgegrcaggtttaav-------..........-------------------.------------..Avpp............................tkkRRRCGTV.FVGGVATDRGFCASSLS.......qRACDKLRCTDCNFEVLCFHGRAWDD........Q...TD.YMFL.R.NNVPDTDKLSA.......R...............LTPCSDSCAYACQCSWQNV.....KDVRALSPT...ERPRWACGGH...............
E9BR84_LEIDB/163-313             ....daghptlqqlraiaaneqasldtsriqamlrkgafhaaiaklgngcldhhgdft-------..........-------------------.------------..-..................................-------.---------------VD........GGCPNILCRQCNYMVVRLQGAEWDD........D..gVNlYLTL.R.NYYPDWCRLAS.......AtpvgvedgaeasrgvLRSSSAAAAYCCQCSWVTV.....RSAKM----...----------vietrltdi......
#=GC seq_cons                    ...........................................................sshlp...........h.pp.t..t.......s.p..ts.sstss........................................tppCssl.alGGoshspGluoshsp........RuCDpLRChsCDFtVlpasDhhWDc........S...sD.YLFF.R.NNhP-hpKL+s.......K...............LhccpGsRAYACQCSWpol.....p-lscLpst...ppL+WVCutH...............
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