GenomeNet

Database: Pfam
Entry: RP1-2
LinkDB: RP1-2
Original site: RP1-2 
#=GF ID   RP1-2
#=GF AC   PF12042.7
#=GF DE   Tubuliform egg casing silk strands structural domain
#=GF AU   Mistry J, Gavin OL
#=GF SE   pdb_2k3n
#=GF GA   21.10 21.10;
#=GF TC   23.30 23.60;
#=GF NC   19.90 20.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   19458259
#=GF RT   Solution structure of eggcase silk protein and its implications
#=GF RT   for silk fiber formation.
#=GF RA   Lin Z, Huang W, Zhang J, Fan JS, Yang D;
#=GF RL   Proc Natl Acad Sci U S A. 2009;106:8906-8911.
#=GF DR   INTERPRO; IPR021915;
#=GF CC   Spiders use fibroins to make silk strands. This family includes
#=GF CC   tubuliform silk fibroins which are used to protect egg cases.
#=GF CC   This domain is a structural domain which is found in repeats of
#=GF CC   up to 20 in many individuals (although this is not necessarily
#=GF CC   the case). RP1 makes up structural domains in the N terminal
#=GF CC   while RP2 makes up structural domains in the C terminal. [1]
#=GF SQ   37
#=GS A0A087URD1_9ARAC/3529-3695  AC A0A087URD1.1
#=GS A0A087URD1_9ARAC/1398-1565  AC A0A087URD1.1
#=GS A0A087TBY8_9ARAC/1504-1662  AC A0A087TBY8.1
#=GS A0A087URD1_9ARAC/623-793    AC A0A087URD1.1
#=GS A0A087URD1_9ARAC/2175-2345  AC A0A087URD1.1
#=GS A0A087URD1_9ARAC/816-983    AC A0A087URD1.1
#=GS A0A087U004_9ARAC/192-357    AC A0A087U004.1
#=GS A0A087URD1_9ARAC/1013-1177  AC A0A087URD1.1
#=GS A0A087TBY8_9ARAC/899-1066   AC A0A087TBY8.1
#=GS A0A087URD1_9ARAC/2945-3114  AC A0A087URD1.1
#=GS A0A087TBY8_9ARAC/1102-1274  AC A0A087TBY8.1
#=GS A0A087URD1_9ARAC/1790-1953  AC A0A087URD1.1
#=GS A0A087TBZ4_9ARAC/231-382    AC A0A087TBZ4.1
#=GS A0A087U004_9ARAC/834-991    AC A0A087U004.1
#=GS A0A087UQ25_9ARAC/559-680    AC A0A087UQ25.1
#=GS A0A087URD1_9ARAC/235-407    AC A0A087URD1.1
#=GS A0A087U004_9ARAC/3231-3394  AC A0A087U004.1
#=GS A0A087U004_9ARAC/683-839    AC A0A087U004.1
#=GS A0A087UJV0_9ARAC/60-194     AC A0A087UJV0.1
#=GS A0A087U004_9ARAC/3895-4061  AC A0A087U004.1
#=GS A0A087URD1_9ARAC/3723-3886  AC A0A087URD1.1
#=GS A0A087URD1_9ARAC/433-595    AC A0A087URD1.1
#=GS A0A087URD1_9ARAC/2561-2752  AC A0A087URD1.1
#=GS A0A087URD1_9ARAC/1589-1758  AC A0A087URD1.1
#=GS A0A087TBY8_9ARAC/696-874    AC A0A087TBY8.1
#=GS A0A087URD1_9ARAC/1979-2146  AC A0A087URD1.1
#=GS A0A087URD1_9ARAC/3336-3501  AC A0A087URD1.1
#=GS A0A087TBY8_9ARAC/1301-1462  AC A0A087TBY8.1
#=GS A0A087URD1_9ARAC/1203-1372  AC A0A087URD1.1
#=GS A0A087URD1_9ARAC/3139-3306  AC A0A087URD1.1
#=GS A0A087UPZ6_9ARAC/42-158     AC A0A087UPZ6.1
#=GS A0A087U004_9ARAC/1772-1936  AC A0A087U004.1
#=GS A0A087TBY8_9ARAC/334-498    AC A0A087TBY8.1
#=GS A0A087URD1_9ARAC/2754-2919  AC A0A087URD1.1
#=GS A0A087URD1_9ARAC/3911-4079  AC A0A087URD1.1
#=GS A0A087URD1_9ARAC/2362-2532  AC A0A087URD1.1
#=GS A0A087TBY8_9ARAC/522-695    AC A0A087TBY8.1
A0A087URD1_9ARAC/3529-3695             ...............ypapsg--------AAVPSRV.................ISEVANKLASALLRSSVFQRAFNTRVSSSVANRIASALAQSIASSLQLDyATASKCRNAIMQALSGVRSGSDTSVYALAIASALAGQLAATGRLS..ASNAS.GIGSSLLSGVVQGSYSGARQAGV.......DLSGVDVSSDISSSLSAYGADSSAGQDIAP-s...........................
A0A087URD1_9ARAC/1398-1565             ..................dyg-----APSAGAAPSV.................VSDVANTLASGLLTSNAFQRAFNSRISSSVANRIAAALAQSVASSMQLDyGTASKCRNAIMQALSSVRSGSDTRVYALTIASSLATQLANAGVLN..ASNMS.SIGSSLLSSVVQGAYSGARQAGI.......DVSGIDVSSDISSSISAYGG-----------srtggqetgist................
A0A087TBY8_9ARAC/1504-1662             .......qdatsaastaagga--------------Qvagtss....tatdigvISKFTNTVSSSLLSSNDFTSIFGSGLPVTTAFNLASNLAQSLATQIGLDeAGINSLLSLLSQYISAIGSSADASAYANALSLAIGNTLAKAGNLS..PILTA.SLASADAQPIANLVNSVTSSTL-.......-------------------------------iaqqpnlir...................
A0A087URD1_9ARAC/623-793               ..............ygalsgg---------AVPSAV.................ISDVANNLASALLRSNIFQRSFNARISASVANRIAAALAQSIASSFQLDyATASKCRNAIMQALSSVRSGSDTRTYATAIATTLASQLAAAGRLN..TSNAS.GIGTTLLSGVLQGAYSGARQAGV.......DVSGVDVSTDISSSVSAY-------------aggpaagqvpamsaqya...........
A0A087URD1_9ARAC/2175-2345             ............gepsaavlp------------SSI.................ISDVANNLASALLRSNIFQRAFNARISSSVANRIAAALAQSISSSMQLDyATASKCRNAIMQALSGVRSGSDTRVYALAIASALVAQLAAAGRLN..ASNAS.GIGSSVLPGVVQGAYSGARQAGV.......DVTGVDLSSDISSSISAFGGSSIGGQGI---aaapqfae....................
A0A087URD1_9ARAC/816-983               ................dygap------SSGAVPSSL.................ISDVANNIASALLRSNIFQRAFNARVSTSVANRIAVALTQSIASTFQLDyGTASKCRNAVMQALSSVRSGSDTRVYALAIASALAAQLAAAGRLN..ASNAS.SIGSSLLSGVVQGAYSGARQAGV.......DVSGVDVSSDISSSISAYGAGSAAGQD----ivaa........................
A0A087U004_9ARAC/192-357               ...............aastdk-----ETTSQQVTSA.................SSSFIEQLYNALINDSGFQSAFSGTVSTNIINAFATAIAGSVASASEFSsVGYSSLVKAYLQALSSEKDGATIEDYARAIATATSNVLEQNGIFS..EGVAS.GHITAAVNAITSGISSTHITESA.......VTTTSV--GSQTTVSSDAG------------tssgvghipa..................
A0A087URD1_9ARAC/1013-1177             .............apapgvap------------SGV.................ISDVANNLASALLRSNIFQRAFNARVSSSVANRISAALAQTIASSLQLDyATAVKCRNAIMQAISGVRSGSDTRAYALAIASALAAQLGNAGRLN..ASNAS.GIGSSLLSGVVQGAYSGARQAGV.......DMSGVDVSSDISSSISAYSAG----------ptagqvpavt..................
A0A087TBY8_9ARAC/899-1066              ...................pg----QSASAAASAAAgggqgvgtsstttdidvISKFTNAITSTLLSSNDFTSLFKSGLPVTAAVNLASNLALSLANQIGLDqAGINSLLSLLSQYISTIDSSADASAYANALSLAIVNTLANAESLS..PTLAS.YLASADTQPFANFVSSVTSRTL-.......-------------------------------naqqpkivrngrtssf............
A0A087URD1_9ARAC/2945-3114             .........adfsvasggalp------------SDV.................ISDVANNLASALLRSNVFQRSFNPRVSSSVTNRIAAALAQSICTSLQLDyRTASKCRSAIMQALSSVRTGSDTRVYALAIASALAAQLAASGRLN..ASNAS.SIGSSLLSGVVQGAYSGARQAGV.......DVSGVDVSTDISSSISAYGAGSTAAQDISA-aa..........................
A0A087TBY8_9ARAC/1102-1274             .............qgaiaaas--------AAAGGAQvagtsn....satdidvISKFINTISSSLLSSNDFTSIFGSGLPVTSALNLASNLAHSLATQIGLDeAGINSLLSLLSQYISAIDSSADASAYANALSLAIGSTLASAGSLS..PALAS.SLASADTQRIANFVSSVTSRTLN.......-------------------------------tqqpnlvrsgvastfrnaplaa......
A0A087URD1_9ARAC/1790-1953             ...........svpavptgii---------------.................-SDVANNIASALLRSNIFQRAFNARVSTSVANRIAAALAQTIASSLQLDnATAAKCRNAIMQALSGVRSGSDTRIYALAIASALAGQLAAAGRLN..ASNAS.GIGSSLLSGVVQGAYSGARQTGI.......DVSGVDVSSDISSSISAFAAGSTAGQDVAS-aq..........................
A0A087TBZ4_9ARAC/231-382               ............ymstdeiqk---------------.................AKKFSETLFVALLKSNLFRETFVRTISKVRAQYLAFKMAFHAITNYGYS.EYAKETAYACAASIKLLPKNSAPQAFGGKISKAITSIFYQKGLIQenTREQAqYLASEMLNYLSNII---------.......-------------------------------svqldsdslilnltrqssrsiddkqgd.
A0A087U004_9ARAC/834-991               ............tfssfvkqs-------------GI.................ASKFASSLYNSLLSNELFQAIFSHIQNTEHLDSYGKALIKNVF-SLGN-.INVSELSDNLLKAFQTIPLGSSLSQYAQVIVNTVAEAFIKHEVLI..PGNEE.SLAASTLNVLISGLREQSEEEAA.......QVSISK-ATAAIPVVAK--------------vetaerpysap.................
A0A087UQ25_9ARAC/559-680               ..................ria---------------.................-------LENALVSSEPFLEIFNPSTTSEDAAIYATLIAREALSEYGA-.PVVEDVDTVVRDAMSNLPPGSSSSDYASSLVNSIIATLNMYGLTT..DIQPE.FLASTMLLNLDS-----------.......-------------------------------eiqkfmasgddsftet............
A0A087URD1_9ARAC/235-407               ................ygtps-------AAVTPSGI.................ISEVTNNLASALLRSNVFQRVFNNRVPSSISTRIASELAQSIISKLQLDyTTASKCRNSIIQAVSGIRSGSDTRVYAQAIASVLTSELATTGRLN..ASNAS.VIGSSILSGILQGAYSAARQAGLdlsgidvTSDISSSLSAYSSSSAAPQTVAET-------qqltav......................
A0A087U004_9ARAC/3231-3394             ................dvgfq-------AAAGTSSY.................AAEFGRQIYDALLSNPRFTETFAGEITLLRIRPFFTVLAENIIAIPVFSsLTLNDLVDPYISAVLRIERGSSLRAYAQEIAGLTVEILLSRNLLT..AEAAS.LARTSVQRAISTALESTSTRTET......sTTTAVETAESES-------------------glaageeegvatgfv.............
A0A087U004_9ARAC/683-839               ................vgstp--------------V.................ARNFGRLIYNSLLADEKFSSVFGIGNSFVNIRLFLTTLATSICSFPQFSsVTVSELVGKYIQAITPIPQGSDIHQYAQAIAQATAEIMSSRKLLS..LQGVT.ALSSSLESAISSALESSSKST--.......SVTQKSSSEIITTATAESGET----------teitfssfv...................
A0A087UJV0_9ARAC/60-194                .................agin-----------AQDT.................TAAFSDSLYFQLMNSMAFRNIFDGRATPDFIINVGRNIAQGIALELRL-.QDVSSVINFIVNTLSSVYPGAGPEEYASAIADSILQIMLTNNILT..GNNPL.TFAGRLASIIDNALS--------.......-------------------------------lnlsagasldnfgs..............
A0A087U004_9ARAC/3895-4061             ................nvgfq-------AAAGTTSY.................AAEFGRQIYDALLSNPRFTETFAGEITLLRIRPFFTVLAENIIAIPVFSsLTLNDLVDPYISAVLRIERGSSLRAYAQEIAGLTVEILLSRNLLT..AEAAS.LARTSVQRAISTALESTSTRTET......sTTTAVETAESES-------------------glaageeegvatgfvara..........
A0A087URD1_9ARAC/3723-3886             ..........ygapsggavps-------------GV.................ISDVANNLASALLRSNIFQRAFNGRVSSSVANRIGAALAQSIASTLQLDyGTAAKCRNAIMQALSGVRSGSDTRVYALAIASAVVAQLAAAGRLN..TSNAS.GIGSSLLSGVVQGTYSGAKQAGV.......DVSGVDVSSDISSSISAYGA-----------gpmgevss....................
A0A087URD1_9ARAC/433-595               .............savnvpsg--------------V.................ISNVANNLVTALLRSNVFQRAFNSRVPSSVVNRIAVALAQSIASSLQLDyGTASKCRNAITQALAGVRSGSDTRAYAVAIASAVSGQLAAVGRLN..SSNAS.SIGSSLLSSVVQGAYSAARQAGI.......DVSGVDVSSDISSSISAYGTGPAVAFDTA--it..........................
A0A087URD1_9ARAC/2561-2752             .........epsaavlpsgii---------------.................-SDVGNNLASALLRSNVFQRAFNARISSSVVSRIATALTQSISSSMQLDyATASKCRNAIMQALSGVRSGSDTRTYALAIASALVAQLAAAGRLN..ASNAS.GIGSSLLSGVVQGAYSGARQAGV.......DVTGVDVSSDISSSISAFGGSSTGGQGIAA-aqqfaesisdisqgvsgvseaiagsgad
A0A087URD1_9ARAC/1589-1758             .................gady----GASSTGAAQSA................vVSDVANKIASALLRSNLFQRVFNTRISSSVASRIATTLAQTTASSLQLDyGTASKCRNAIMQALSGVRTGSDTRVYALAIASALAAQLAASGRLN..ASNAS.GIGSSVISGVVQGTYSGASQAGV.......DVSGVDVSSDISSSISAYGRGSAVGQDIA--gp..........................
A0A087TBY8_9ARAC/696-874               .......fpgqsgasaaataa--------------AgggqgagtsstttdievISKFTNTVISSLLSSNDFTSIFGSGLPVTTALNLASNLAQSLATQIGLDeAGINSVLSLLNQYISAIDPSADASTYANALSLAIGNTLASAGSLS..PALAS.SLASVDAQPIANFVSSVASKTLN.......-------------------------------aqqpnlvrsggtstfrnvpfkqvq....
A0A087URD1_9ARAC/1979-2146             ........dygaptsgavpsg--------------I.................ISDVANNLASALLRSNVFKRAFNVRVSSNVANRIAGALAQSIASSLQLDfGTASKCRNAITQALSGVRSGSDTRVYALAISSALTAQLAAAGRLN..ASNAS.GIGSSLLSGVVQGTYSGAKQAGV.......DVSGVDVSSDISSSVSAYGAGPTGAQE----sdvs........................
A0A087URD1_9ARAC/3336-3501             .........gapsgsvvpsgl---------------.................ISEVASKLASALLRSNIFQLAFNARVSSSVASRIAAVLVQSIASSLQLDyGTASKCRNAIMQALSGVRTGSETRAYALTVASALATQLAGAGRLN..ASNAS.DIGSSVLSAAVQGAYSGASQAGV.......DVSGVDVSSDISSSISAYGAGPTGGSET---glt.........................
A0A087TBY8_9ARAC/1301-1462             ...................pg----QSASAATSTAAggaqgagtygtatdidvISKFTNTISSSLLSSNDFTSIFGSELPVATAFNLASNLAQSLATQIGLDeAGINSLLSLLSQYISAIGSSGDASAYANALSLAIGNTLASAGSLS..PALAS.SLASANAQAIANFVRSVTSR---.......-------------------------------tlnvqqpilvgs................
A0A087URD1_9ARAC/1203-1372             ...............aeygap------SSGAVPSAL.................ISDLANNLASALLRSNVFQRAFNARNSSAVTNRIAAALAQSIVSSLQLDyGTASKFRNAITQALSSVRSGSNTRVYALAIASALAAQLAAAGRLN..ASNAS.SIGSSLLSGVVQGAYSGARQAGV.......DVSGVDVSSDISSSISAYGAGSAAGQ-----dvvaaq......................
A0A087URD1_9ARAC/3139-3306             .......sdygapssggvpsg--------------L.................ISDIASNLASALVRSKIFQRAFNARVSSSIANRIASALTQSIASSLQLDnTTASKCRIAVTQALSSVRSGSDTRAYALSIASALARQLAAVGRLN..SSNAS.SIGSSLLSGVVQGAYSGARQAGV.......DVSGVDVSSDISSSVSAYGAGRTVSSE----tdv.........................
A0A087UPZ6_9ARAC/42-158                ..............aidgtve---------------.................-ESFRESLYSQIINSASFSIKFGGSVTDVDIINVGRNIATGIASELNL-.QDYDSVSNFMISALGSVYPVGKLEDYASIIVEAVLELLSTYNILN..EYN--.-----------------------.......-------------------------------yfdlslrigniidst.............
A0A087U004_9ARAC/1772-1936             .................gyqa--------AAGTSVF.................AADFGRQIYEALLSNPKFAEAFTGAITILRIRPFFTVLAENIIAIPVFSsLTLNELVDPYISAVLRIERGSSLRAYAQEIAGLTVEILLSRNLLT..AEAAS.LARTSVQSAISTALESTSTTTET.......-STTSAVATAESEGVVA--------------agaeegvatgfvara.............
A0A087TBY8_9ARAC/334-498               ................dreil-------SSSSDIDV.................ISKFTNSITSSLLSSNDFTSTFRTGLPATTAVNLASSLARSFATQMALDeTTINTLLPLVSQYVSEISSSADVSAYANAISRAVGDALASTGNVP..PVLTA.SLAPADTQPIANLVNSVTSTNVNe.....qQ------------------------------snlvrrgggstlrniaakqvqenrqn..
A0A087URD1_9ARAC/2754-2919             .........gapsgvvvpsgi---------------.................ISDVANNLASALLRSNVFQRAFNARISSSIANKVAAALTQTLASSLQLDySTAAKCRNAIMQALSAVRSGSDTRVYALAIASSLVAQLAAAGRLD..ASNAS.GIGSSLLSGVVQGAYSGARQAGV.......DVSGIDVSTDISSSISTYGAGSPAGQDIAA-t...........................
A0A087URD1_9ARAC/3911-4079             ...............adygap------SAAAVPSGV.................ISDVVNNLASALLRSNSFQRAFNARVSSSVANRIVVALSQSIASNLQLDyGTASKLRNAVVQALSGVRSGSDTRVYAVTIASSLAAQLANAGLLK..ASNAS.SIGSSLLSSIVQGSYSGARQAGV.......DVSGIDIRSDISTSASAYSSSASSIQTSS--vs..........................
A0A087URD1_9ARAC/2362-2532             .........sadygaltsgav-----------PSGV.................ISDVANNLASALLRSNVFQRAFNVRVSSSVANRIAGVLAQSIASSLQLDyGTASKCRNAIMQALSGVRSGSDTRVYALAIASALTTQLAAAGRLN..ESNAS.GIGSSLLSGVVQGTYSGAKQAGV.......DVSGVDVSSDISSSVSAYGAGPTGAQES---vvss........................
A0A087TBY8_9ARAC/522-695               asaaanggsggaqatditsta--------------Rni.............dvISQFTNTITSSLLSSNEFTSIFGSGLPVTTALNLASNLAQSLAAQIGLDeTGINYLLSLLRQYISAIDLSADASAYANAVSRAIGNALASAGNLS..PALAS.SLASADTQPIANLVNSVTSSTLI.......-------------------------------aqqpkligsggastvgtkpepslsg...
#=GC seq_cons                          ................sssss..............h.................ISchuNsLsSALLpSNhFpcsFsuclososAsplAssLAQSIASplpLD.sTsucspsslhQAlSulcoGSDs+sYA.AIAsAlsspLAusGpLs..suNAS.uluSSllsulspus.Ssuppsss.......ssos.s.uss.Sss.ut..............st..........................
//
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